Identifiera nya molekylära mål för behandling av motorneuronsjukdomar – Eva Hedlunds forskargrupp

Publikationer

Utvalda publikationer

• Article: GENOME RESEARCH. 2020;30(8):1083-1096

  LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy

  Nichterwitz S; Nijssen J; Storvall H; Schweingruber C; Comley LH; Allodi I; van der Lee M; Deng Q; Sandberg R; Hedlund E
• Article: ACTA NEUROPATHOLOGICA. 2020;139(5):837-853

  Synaptotagmin 13 is neuroprotective across motor neuron diseases

  Nizzardo M; Taiana M; Rizzo F; Benitez JA; Nijssen J; Allodi I; Melzi V; Bresolin N; Comi GP; Hedlund E; Corti S
• Article: STEM CELL REPORTS. 2019;12(6):1329-1341

  Modeling Motor Neuron Resilience in ALS Using Stem Cells

  Allodi I; Nijssen J; Benitez JA; Schweingruber C; Fuchs A; Bonvicini G; Cao M; Kiehn O; Hedlund E
• Article: STEM CELL REPORTS. 2018;11(6):1565-1578

  Axon-Seq Decodes the Motor Axon Transcriptome and Its Modulation in Response to ALS

  Nijssen J; Aguila J; Hoogstraaten R; Kee N; Hedlund E
• Review: MOLECULAR ASPECTS OF MEDICINE. 2018;59:36-46

  Single-cell RNA sequencing: Technical advancements and biological applications

  Hedlund E; Deng Q
• Review: ACTA NEUROPATHOLOGICA. 2017;133(6):863-885

  Motor neuron vulnerability and resistance in amyotrophic lateral sclerosis

  Nijssen J; Comley LH; Hedlund E
• Article: NATURE COMMUNICATIONS. 2016;7:12139

  Laser capture microscopy coupled with Smart-seq2 for precise spatial transcriptomic profiling

  Nichterwitz S; Chen G; Benitez JA; Yilmaz M; Storvall H; Cao M; Sandberg R; Deng Q; Hedlund E
• Article: SCIENTIFIC REPORTS. 2016;6:25960

  Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS

  Allodi I; Comley L; Nichterwitz S; Nizzardo M; Simone C; Benitez JA; Cao M; Corti S; Hedlund E

Medarbetare och kontakt

Gruppledare

• 

  Eva Hedlund

  Senior Forskare | Docent

  E-postadress eva.hedlund@ki.se

Alla medarbetare i gruppen

• Shangli Cheng

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  E-postadress shangli.cheng@ki.se
• Nils Dennhag

  Laboratorietekniker

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• Larissa Kahnwald

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  E-postadress larissa.kahnwald@ki.se
• Mélanie Leboeuf

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  E-postadress melanie.leboeuf@ki.se
• Tina Noreng Karlsson

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  E-postadress tina.noreng.karlsson@ki.se
• Christina Toumpa

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  E-postadress christina.toumpa@ki.se
• Sagar Verma

  Postdoktorala Studier

  E-postadress sagar.verma@ki.se
• Yan Wu

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  E-postadress yan.wu@ki.se
• Rianne de Jongh

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  E-postadress rianne.de.jongh@ki.se