Gilad Silberbergs grupp

Vi studerar de strukturella och funktionella egenskaperna hos neokortikala och striatala mikrokretsar samt interaktionen mellan dessa två hjärnområden (kortiko-striatal väg).

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Institutionen för neurovetenskap

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Publikationer

Utvalda publikationer

Article: CURRENT OPINION IN NEUROBIOLOGY. 2023;83:102781
Corticostriatal pathways for bilateral sensorimotor functions
Gomez-Ocadiz R; Silberberg G
Article: NATURE COMMUNICATIONS. 2023;14(1):1004
Ongoing movement controls sensory integration in the dorsolateral striatum
de la Torre-Martinez R; Ketzef M; Silberberg G
Article: CELL REPORTS. 2022;39(8):110842
GABAergic interneurons expressing the α2 nicotinic receptor subunit are functionally integrated in the striatal microcircuit
Tokarska A; Silberberg G
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(33):e2104119118
Astrocyte-derived neurons provide excitatory input to the adult striatal circuitry
Dorst MC; Diaz-Moreno M; Dias DO; Guimaraes EL; Holl D; Kalkitsas J; Silberberg G; Goritz C
Article: NEURON. 2021;109(3):516-529.e4
Differential Synaptic Input to External Globus Pallidus Neuronal Subpopulations In Vivo
Ketzef M; Silberberg G
Article: NATURE COMMUNICATIONS. 2020;11(1):5113
Polysynaptic inhibition between striatal cholinergic interneurons shapes their network activity patterns in a dopamine-dependent manner
Dorst MC; Tokarska A; Zhou M; Lee K; Stagkourakis S; Broberger C; Masmanidis S; Silberberg G
Article: CURRENT BIOLOGY. 2020;30(14):2777-2790.e4
Synaptic Connectivity between the Cortex and Claustrum Is Organized into Functional Modules
Chia Z; Augustine GJ; Silberberg G
Article: CELL REPORTS. 2020;30(4):1178-1194.e3
The Functional Organization of Cortical and Thalamic Inputs onto Five Types of Striatal Neurons Is Determined by Source and Target Cell Identities
Johansson Y; Silberberg G
Article: NEURON. 2017;94(4):855-865.e5
Dopamine Depletion Impairs Bilateral Sensory Processing in the Striatum in a Pathway-Dependent Manner
Ketzef M; Spigolon G; Johansson Y; Bonito-Oliva A; Fisone G; Silberberg G
Review: CURRENT OPINION IN NEUROBIOLOGY. 2015;33:182-187
Local and afferent synaptic pathways in the striatal microcircuitry
Silberberg G; Bolam JP
Article: NEURON. 2014;83(5):1200-1212
Multisensory Integration in the Mouse Striatum
Reig R; Silberberg G

Alla gruppmedlemmars publikationer

Preprint: BIORXIV. 2024
A Prefrontal Cortex Map based on Single Neuron Activity
Le Merre P; Heining K; Slashcheva M; Jung F; Moysiadou E; Guyon N; Yahya R; Park H; Wernstal F; Carlén M
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024;121(45):e2403325121
Learning-dependent gating of hippocampal inputs by frontal interneurons.
Zhang C-L; Sontag L; Gómez-Ocádiz R; Schmidt-Hieber C
Preprint: BIORXIV. 2024
Nicotine engages a VTA-NAc feedback loop to inhibit amygdala-projecting dopamine neurons and induce anxiety
Le Borgne T; Nguyen C; Vicq E; Jehl J; Solié C; Guyon N; Daussy L; Gulmez A; Reynolds LM; Mondoloni S; Tolu S; Pons S; Maskos U; Valjent E; Mourot A; Faure P; Marti F
Journal article: ELIFE. 2024;12
Serotonergic and dopaminergic neurons in the dorsal raphe are differentially altered in a mouse model for parkinsonism
Boi L; Johansson Y; Tonini R; Moratalla R; Fisone G; Silberberg G
Preprint: ELIFE. 2024
Serotonergic and dopaminergic neurons in the dorsal raphe are differentially altered in a mouse model for parkinsonism
Boi L; Johansson Y; Tonini R; Moratalla R; Fisone G; Silberberg G
Preprint: ELIFE SCIENCES PUBLICATIONS, LTD. 2024
Serotonergic and dopaminergic neurons in the dorsal raphe are differentially altered in a mouse model for parkinsonism
Boi L; Johansson Y; Tonini R; Moratalla R; Fisone G; Silberberg G
Article: ISCIENCE. 2024;27(4):109583
The single D380 amino acid substitution increases pneumolysin cytotoxicity towards neuronal cells
Serra S; Iannotti V; Ferrante M; Tofiño-Vian M; Baxendale J; Silberberg G; Kohler TP; Hammerschmidt S; Ulijasz AT; Iovino F
Preprint: ELIFE SCIENCES PUBLICATIONS, LTD. 2024
Serotonergic and dopaminergic neurons in the dorsal raphe are differentially altered in a mouse model for parkinsonism
Boi L; Johansson Y; Tonini R; Moratalla R; Fisone G; Silberberg G
Preprint: BIORXIV. 2024
Motor cortex directly excites the output nucleus of the basal ganglia, the substantia nigra pars reticulata
Thompson WS; Grillner S; Silberberg G
Newspaper article: NATIONAL GEOGRAPHIC. 2023
Por qué consumimos más en Navidad (y cómo evitarlo con neurociencia)
Perez Fernandez J; De La Torre Martinez R
Article: CURRENT OPINION IN NEUROBIOLOGY. 2023;83:102781
Corticostriatal pathways for bilateral sensorimotor functions
Gomez-Ocadiz R; Silberberg G
Preprint: BIORXIV. 2023
The interpeduncular nucleus blunts the rewarding effect of nicotine
Jehl J; Ciscato M; Vicq E; Dejean de la Batie G; Guyon N; Mondoloni S; Frangieh J; Nguyen C; Hardelin J-P; Marti F; Corringer P-J; Faure P; Mourot A
Preprint: BIORXIV. 2023
Dopamine enhances multisensory responses in the dorsomedial striatum
Sáez M; Alegre-Cortés J; Morgenstern NA; García-Frigola C; de la Torre-Martínez R; Reig R
Newspaper article: CNN. 2023
Why a vacation is good for you – even before you take time off
Perez Fernandez J; De La Torre Martinez R
Preprint: ELIFE SCIENCES PUBLICATIONS, LTD. 2023
Serotonergic and dopaminergic neurons in the dorsal raphe are differentially altered in a mouse model for Parkinson’s disease
Boi L; Johansson Y; Tonini R; Moratalla R; Fisone G; Silberberg G
Preprint: AUTHOREA, INC.. 2023
Oxaliplatin reversibly and differentially affects electrogenic activity of small IB4(+) of male and female rat sensory neurons
Villalba-Riquelme E; Martínez RDLT; Fernandez-Carvajal A; Ferrer-Montiel A
Preprint: BIORXIV. 2023
Serotonergic and dopaminergic neurons in the dorsal raphe are differentially altered in a mouse model for parkinsonism
Boi L; Johansson Y; Tonini R; Moratalla R; Fisone G; Silberberg G
Preprint: BIORXIV. 2023
Presynaptic and Postsynaptic Determinants of the Functional Connectivity Between the Claustrum and Anterior Cingulate Cortex
de la Torre-Martínez R; Chia Z; Tokarska A; Frost-Nylén J; Augustine G; Silberberg G
Article: NATURE COMMUNICATIONS. 2023;14(1):1004
Ongoing movement controls sensory integration in the dorsolateral striatum
de la Torre-Martinez R; Ketzef M; Silberberg G
Article: CELL REPORTS. 2023;42(1):111952
Sensory processing in external globus pallidus neurons
Johansson Y; Ketzef M
Preprint: BIORXIV. 2022
Action prediction error: a value-free dopaminergic teaching signal that drives stable learning
Greenstreet F; Vergara HM; Johansson Y; Pati S; Schwarz L; Lenzi SC; Wisdom M; Gubanova A; Marbach F; Rollik L; Kaur J; Moskovitz T; Cohen J; Thompson E; Margrie TW; Clopath C; Stephenson-Jones M
Journal article: NATURE COMMUNICATIONS. 2022;13(1):4122
A synaptic signal for novelty processing in the hippocampus
Gomez-Ocadiz R; Trippa M; Zhang C-L; Posani L; Cocco S; Monasson R; Schmidt-Hieber C
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2022;179(14):3693-3710
Paclitaxel in vitro reversibly sensitizes the excitability of IB4(-) and IB4(+) sensory neurons from male and female rats
Villalba-Riquelme E; De La Torre-Martinez R; Fernandez-Carvajal A; Ferrer-Montiel A
Article: CELL REPORTS. 2022;39(8):110842
GABAergic interneurons expressing the α2 nicotinic receptor subunit are functionally integrated in the striatal microcircuit
Tokarska A; Silberberg G
Article: ELIFE. 2022;11:e75829
A tonic nicotinic brake controls spike timing in striatal spiny projection neurons
Matityahu L; Malgady JM; Schirelman M; Johansson Y; Wilking JA; Silberberg G; Goldberg JA; Plotkin JL; Ding J
Preprint: BIORXIV. 2022
Sensory responses in dorsolateral striatum are modulated by motor activity in a dopamine-dependent manner
de la Torre-Martinez R; Ketzef M; Silberberg G
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(5):2692
β-Lactam TRPM8 Antagonist RGM8-51 Displays Antinociceptive Activity in Different Animal Models.
Martín-Escura C; Medina-Peris A; Spear LA; de la Torre Martínez R; Olivos-Oré LA; Barahona MV; González-Rodríguez S; Fernández-Ballester G; Fernández-Carvajal A; Artalejo AR; Ferrer-Montiel A; González-Muñiz R
Article: FRONTIERS IN COMPUTATIONAL NEUROSCIENCE. 2022;16:806086

Data-Driven Model of Postsynaptic Currents Mediated by NMDA or AMPA Receptors in Striatal Neurons

Carannante I; Johansson Y; Silberberg G; Hellgren Kotaleski J
Preprint: BIORXIV. 2021
A tonic nicotinic brake controls spike timing in striatal spiny projection neurons
Matityahu L; Malgady J; Schirelman M; Johansson Y; Wilking J; Silberberg G; Goldberg J; Plotkin J
Newspaper article: BBC NEWS. 2021
Día Mundial de la Salud Mental: qué hacer cuando sentimos que no podemos más
De La Torre Martinez R; Perez Fernandez J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(33):e2104119118
Astrocyte-derived neurons provide excitatory input to the adult striatal circuitry
Dorst MC; Diaz-Moreno M; Dias DO; Guimaraes EL; Holl D; Kalkitsas J; Silberberg G; Goritz C
Thesis / dissertation: 2021
On the role of parvalbumin interneurons in neuronal network activity in the prefrontal cortex
Guyon, Nicolas Gustavo
Article: JOURNAL OF NEUROSCIENCE. 2021;41(14):3120-3141
Adult trkB Signaling in Parvalbumin Interneurons is Essential to Prefrontal Network Dynamics.
Guyon N; Zacharias LR; van Lunteren JA; Immenschuh J; Fuzik J; Märtin A; Xuan Y; Zilberter M; Kim H; Meletis K; Lopes-Aguiar C; Carlén M
Article: JOURNAL OF NEUROSCIENCE. 2021;41(13):2944-2963
Network Asynchrony Underlying Increased Broadband Gamma Power.
Guyon N; Zacharias LR; Fermino de Oliveira E; Kim H; Leite JP; Lopes-Aguiar C; Carlén M
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(5):2370
Phenylalanine-Derived β-Lactam TRPM8 Modulators. Configuration Effect on the Antagonist Activity.
Bonache MÁ; Llabrés PJ; Martín-Escura C; De la Torre-Martínez R; Medina-Peris A; Butrón L; Gómez-Monterrey I; Roa AM; Fernández-Ballester G; Ferrer-Montiel A; Fernández-Carvajal A; González-Muñiz R
Preprint: BIORXIV. 2021
A synaptic novelty signal to switch hippocampal attractor networks from generalization to discrimination
Gómez-Ocádiz R; Trippa M; Posani L; Cocco S; Monasson R; Schmidt-Hieber C
Article: NEURON. 2021;109(3):516-529.e4
Differential Synaptic Input to External Globus Pallidus Neuronal Subpopulations In Vivo
Ketzef M; Silberberg G
Conference publication: EUROPEAN BIOPHYSICS JOURNAL. 2021;50(SUPPL 1):111
Alterations of TRP and Nav channels in chemotherapy-induced peripheral neuropathy: Studying their role using in vitro pre-clinical nociceptor models
Villalba-Riquelme E; de la Torre-Martinez R; Fernandez-Carvajal A; Ferrer-Montiel A
Journal article: NEURON. 2020;108(6):1103-1112.e6
Differential Relation between Neuronal and Behavioral Discrimination during Hippocampal Memory Encoding
Allegra M; Posani L; Gomez-Ocadiz R; Schmidt-Hieber C
Article: NATURE COMMUNICATIONS. 2020;11(1):5113
Polysynaptic inhibition between striatal cholinergic interneurons shapes their network activity patterns in a dopamine-dependent manner
Dorst MC; Tokarska A; Zhou M; Lee K; Stagkourakis S; Broberger C; Masmanidis S; Silberberg G
Preprint: BIORXIV. 2020
Network asynchrony underlying increased broadband gamma power
Guyon N; Zacharias LR; de Oliveira EF; Kim H; Leite JP; Lopes-Aguiar C; Carlén M
Article: SCIENTIFIC REPORTS. 2020;10(1):14154
Highly functionalized β-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity.
Bonache MÁ; Martín-Escura C; de la Torre Martínez R; Medina A; González-Rodríguez S; Francesch A; Cuevas C; Roa AM; Fernández-Ballester G; Ferrer-Montiel A; Fernández-Carvajal A; González-Muñiz R
Thesis / dissertation: 2020
Neuromodulation shapes interneuron communication in the mouse striatum
Dorst, Matthijs Constantijn
Article: CURRENT BIOLOGY. 2020;30(14):2777-2790.e4
Synaptic Connectivity between the Cortex and Claustrum Is Organized into Functional Modules
Chia Z; Augustine GJ; Silberberg G
Preprint: BIORXIV. 2020
A critical role for trkB signaling in the adult function of parvalbumin interneurons and prefrontal network dynamics
Guyon N; Zacharias LR; van Lunteren JA; Immenschuh J; Fuzik J; Märtin A; Xuan Y; Zilberter M; Kim H; Meletis K; Lopes-Aguiar C; Carlén M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(17):9554-9565
The microcircuits of striatum in silico
Hjorth JJJ; Kozlov A; Carannante I; Nylen JF; Lindroos R; Johansson Y; Tokarska A; Dorst MC; Suryanarayana SM; Silberberg G; Kotaleski JH; Grillner S
Thesis / dissertation: 2020
The functional organisation of basal ganglia inputs
Johansson, Yvonne
Preprint: BIORXIV. 2020
Differential Synaptic Input to External Globus Pallidus Neuronal SubpopulationsIn Vivo
Ketzef M; Silberberg G
Article: CELL REPORTS. 2020;30(4):1178-1194.e3
The Functional Organization of Cortical and Thalamic Inputs onto Five Types of Striatal Neurons Is Determined by Source and Target Cell Identities
Johansson Y; Silberberg G
Article: JOURNAL OF NEUROPHYSIOLOGY. 2019;122(6):2294-2303
Direct pathway neurons in mouse dorsolateral striatum in vivo receive stronger synaptic input than indirect pathway neurons
Filipovic M; Ketzef M; Reig R; Aertsen A; Silberberg G; Kumar A
Article: MOLECULAR PSYCHIATRY. 2019;24(9):1351-1368
A hypothalamus-habenula circuit controls aversion
Lazaridis I; Tzortzi O; Weglage M; Martin A; Xuan Y; Parent M; Johansson Y; Fuzik J; Furth D; Fenno LE; Ramakrishnan C; Silberberg G; Deisseroth K; Carlen M; Meletis K
Article: ACS CHEMICAL NEUROSCIENCE. 2019;10(8):3900-3909
1-(2',5'-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (RGM079): A Positive Allosteric Modulator of α7 Nicotinic Receptors with Analgesic and Neuroprotective Activity.
Pérez de Vega MJ; Fernandez-Mendivil C; de la Torre Martínez R; González-Rodríguez S; Mullet J; Sala F; Sala S; Criado M; Moreno-Fernández S; Miguel M; Fernández-Carvajal A; Ferrer-Montiel A; López MG; González-Muñiz R
Article: CELL REPORTS. 2019;27(11):3182-3198.e9
The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons
Ruud J; Alber J; Tokarska A; Ruud LE; Nolte H; Biglari N; Lippert R; Lautenschlager A; Ciealak PE; Szumiec L; Hess ME; Broenneke HS; Krueger M; Nissbrandt H; Korotkova T; Silberberg G; Parkitna JR; Bruening JC
Preprint: BIORXIV. 2019
Direct Pathway Neurons in Mouse Dorsolateral Striatum In Vivo Receive Stronger Synaptic Input than Indirect Pathway Neurons
Filipović M; Ketzef M; Reig R; Aertsen A; Silberberg G; Kumar A
Article: NATURE COMMUNICATIONS. 2018;9(1):3691
Neuronal heterogeneity and stereotyped connectivity in the auditory afferent system
Petitpre C; Wu H; Sharma A; Tokarska A; Fontanet P; Wang Y; Helmbacher F; Yackle K; Silberberg G; Hadjab S; Lallemend F
Article: NEUROSCIENCE. 2018;381:115-123
A New Micro-holder Device for Local Drug Delivery during In Vivo Whole-cell Recordings
Saez M; Ketzef M; Alegre-Cortes J; Reig R; Silberberg G
Article: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2018;143:157-165
Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of α7 nicotinic receptors with analgesic activity.
Balsera B; Mulet J; Sala S; Sala F; de la Torre-Martínez R; González-Rodríguez S; Plata A; Naesens L; Fernández-Carvajal A; Ferrer-Montiel A; Criado M; Pérez de Vega MJ; González-Muñiz R
Article: FRONTIERS IN NEURAL CIRCUITS. 2018;12:64
Targeting VGLUT2 in Mature Dopamine Neurons Decreases Mesoaccumbal Glutamatergic Transmission and Identifies a Role for Glutamate Co-release in Synaptic Plasticity by Increasing Baseline AMPA/NMDA Ratio
Papathanou M; Creed M; Dorst MC; Bimpisidis Z; Dumas S; Pettersson H; Bellone C; Silberberg G; Luscher C; Wallen-Mackenzie A
Article: FRONTIERS IN NEURAL CIRCUITS. 2018;12:3
Basal Ganglia Neuromodulation Over Multiple Temporal and Structural Scales-Simulations of Direct Pathway MSNs Investigate the Fast Onset of Dopaminergic Effects and Predict the Role of Kv4.2
Lindroos R; Dorst MC; Du K; Filipovic M; Keller D; Ketzef M; Kozlov AK; Kumar A; Lindahl M; Nair AG; Perez-Fernandez J; Grillner S; Silberberg G; Kotaleski JH
Journal article: CLAUSTRUM. 2017;2(1):1357412
Functional properties, topological organization and sexual dimorphism of claustrum neurons projecting to anterior cingulate cortex
Chia Z; Silberberg G; Augustine GJ
Article: SCIENTIFIC REPORTS. 2017;7(1):10766
Synthesis, high-throughput screening and pharmacological characterization of β-lactam derivatives as TRPM8 antagonists.
de la Torre-Martínez R; Bonache MA; Llabrés-Campaner PJ; Balsera B; Fernández-Carvajal A; Fernández-Ballester G; Ferrer-Montiel A; Pérez de Vega MJ; González-Muñiz R
Article: NEURON. 2017;94(4):855-865.e5
Dopamine Depletion Impairs Bilateral Sensory Processing in the Striatum in a Pathway-Dependent Manner
Ketzef M; Spigolon G; Johansson Y; Bonito-Oliva A; Fisone G; Silberberg G
Article: CEREBRAL CORTEX. 2016;26(12):4405-4415
Distinct Corticostriatal and Intracortical Pathways Mediate Bilateral Sensory Responses in the Striatum
Reig R; Silberberg G
Article: JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. 2016;67(6):851-858
Effect of econazole and benzydamine on sensory neurons in culture.
Mathivanan S; de la Torre-Martinez R; Wolf C; Mangano G; Polenzani L; Milanese C; Ferrer-Montiel A
Article: ELIFE. 2016;5:e16088
Secretagogin expression delineates functionally-specialized populations of striatal parvalbumin-containing interneurons
Garas FN; Shah RS; Kormann E; Doig NM; Vinciati F; Nakamura KC; Dorst MC; Smith Y; Magill PJ; Sharott A
Journal article: BMC NEUROSCIENCE. 2016;17(Suppl 1):54
25th Annual Computational Neuroscience Meeting CNS-2016, Seogwipo City, South Korea, July 2-7, 2016 Abstracts
Article: ELIFE. 2016;5:e14170
CO₂-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture
Forsberg D; Horn Z; Tserga E; Smedler E; Silberberg G; Shvarev Y; Kaila K; Uhlen P; Herlenius E
Article: FUTURE MEDICINAL CHEMISTRY. 2016;8(7):731-749
1,3-diphenylpropan-1-ones as allosteric modulators of α7 nACh receptors with analgesic and antioxidant properties.
Criado M; Balsera B; Mulet J; Sala S; Sala F; de la Torre-Martínez R; Fernández-Carvajal A; Ferrer-Montiel A; Moreno-Fernández S; Miguel M; Pérez de Vega MJ; González-Muñiz R
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2016;59(5):2179-2191
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators.
Bertamino A; Ostacolo C; Ambrosino P; Musella S; Di Sarno V; Ciaglia T; Soldovieri MV; Iraci N; Fernandez Carvajal A; de la Torre-Martinez R; Ferrer-Montiel A; Gonzalez Muniz R; Novellino E; Taglialatela M; Campiglia P; Gomez-Monterrey I
Article: RSC ADVANCES. 2016;6(9):6868-6877
New transient receptor potential TRPV1, TRPM8 and TRPA1 channel antagonists from a single linear β,γ-diamino ester scaffold
Perez-Faginas P; Aranda MT; de la Torre-Martinez R; Quirce S; Fernandez-Carvajal A; Ferrer-Montiel A; Gonzalez-Muniz R
Book chapter: ADVANCED PATCH-CLAMP ANALYSIS FOR NEUROSCIENTISTS: NEUROMETHODS. 2016;p. 151-170
Optogenetic Dissection of the Striatal Microcircuitry
Silberberg G; Planert H
Article: CEREBRAL CORTEX. 2016;26(1):96-105
Novel Striatal GABAergic Interneuron Populations Labeled in the 5HT3a^EGFP Mouse
Munoz-Manchado AB; Foldi C; Szydlowski S; Sjulson L; Farries M; Wilson C; Silberberg G; Hjerling-Leffler J
Journal article: AMERICAN JOURNAL OF PHYSIOLOGY - RENAL PHYSIOLOGY. 2015;309(10):F836-F842
Increased phosphorylation of the renal Na⁺-Cl^- cotransporter in male kidney transplant recipient patients with hypertension: a prospective cohort
Rojas-Vega L; Jimenez-Vega AR; Bazua-Valenti S; Arroyo-Garza I; Victor Jimenez J; Gomez-Ocadiz R; Luis Carrillo-Perez D; Moreno E; Morales-Buenrostro LE; Alberu J; Gamba G
Article: CELL. 2015;163(2):456-492
Reconstruction and Simulation of Neocortical Microcircuitry
Markram H; Muller E; Ramaswamy S; Reimann MW; Abdellah M; Sanchez CA; Ailamaki A; Alonso-Nanclares L; Antille N; Arsever S; Kahou GAA; Berger TK; Bilgili A; Buncic N; Chalimourda A; Chindemi G; Courcol J-D; Delalondre F; Delattre V; Druckmann S; Dumusc R; Dynes J; Eilemann S; Gal E; Gevaert ME; Ghobril J-P; Gidon A; Graham JW; Gupta A; Haenel V; Hay E; Heinis T; Hernando JB; Hines M; Kanari L; Keller D; Kenyon J; Khazen G; Kim Y; King JG; Kisvarday Z; Kumbhar P; Lasserre S; Le Be J-V; Magalhaes BRC; Merchan-Perez A; Meystre J; Morrice BR; Muller J; Munoz-Cespedes A; Muralidhar S; Muthurasa K; Nachbaur D; Newton TH; Nolte M; Ovcharenko A; Palacios J; Pastor L; Perin R; Ranjan R; Riachi I; Rodriguez J-R; Riquelme JL; Roessert C; Sfyrakis K; Shi Y; Shillcock JC; Silberberg G; Silva R; Tauheed F; Telefont M; Toledo-Rodriguez M; Traenkler T; Van Geit W; Diaz JV; Walker R; Wang Y; Zaninetta SM; DeFelipe J; Hill SL; Segev I; Schuermann F
Article: NEUROBIOLOGY OF DISEASE. 2015;81:4-13
Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures.
Gilad D; Shorer S; Ketzef M; Friedman A; Sekler I; Aizenman E; Hershfinkel M
Article: JOURNAL OF IMMUNOLOGY. 2015;195(4):1713-1722
Differential TGF-β Signaling in Glial Subsets Underlies IL-6-Mediated Epileptogenesis in Mice.
Levy N; Milikovsky DZ; Baranauskas G; Vinogradov E; David Y; Ketzef M; Abutbul S; Weissberg I; Kamintsky L; Fleidervish I; Friedman A; Monsonego A
Review: CURRENT OPINION IN NEUROBIOLOGY. 2015;33:182-187
Local and afferent synaptic pathways in the striatal microcircuitry
Silberberg G; Bolam JP
Article: FRONTIERS IN NEURAL CIRCUITS. 2015;9:60
Long-range recruitment of Martinotti cells causes surround suppression and promotes saliency in an attractor network model
Krishnamurthy P; Silberberg G; Lansner A
Article: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2014;86:724-739
Chalcones as positive allosteric modulators of α7 nicotinic acetylcholine receptors: a new target for a privileged structure.
Balsera B; Mulet J; Fernández-Carvajal A; de la Torre-Martínez R; Ferrer-Montiel A; Hernández-Jiménez JG; Estévez-Herrera J; Borges R; Freitas AE; López MG; García-López MT; González-Muñiz R; Pérez de Vega MJ; Valor LM; Svobodová L; Sala S; Sala F; Criado M
Article: NEURON. 2014;83(5):1200-1212
Multisensory Integration in the Mouse Striatum
Reig R; Silberberg G
Article: NATURE NEUROSCIENCE. 2014;17(9):1233-1239
Cerebellum involvement in cortical sensorimotor circuits for the control of voluntary movements
Proville RD; Spolidoro M; Guyon N; Dugue GP; Selimi F; Isope P; Popa D; Lena C
Article: NEURON. 2014;83(3):663-678
A Whole-Brain Atlas of Inputs to Serotonergic Neurons of the Dorsal and Median Raphe Nuclei
Dorocic IP; Furth D; Xuan Y; Johansson Y; Pozzi L; Silberberg G; Carlen M; Meletis K
Article: ACS COMBINATORIAL SCIENCE. 2014;16(5):250-258
De novo designed library of linear helical peptides: an exploratory tool in the discovery of protein-protein interaction modulators.
Bonache MÁ; Balsera B; López-Méndez B; Millet O; Brancaccio D; Gómez-Monterrey I; Carotenuto A; Pavone LM; Reille-Seroussi M; Gagey-Eilstein N; Vidal M; de la Torre-Martinez R; Fernández-Carvajal A; Ferrer-Montiel A; García-López MT; Martín-Martínez M; de Vega MJP; González-Muñiz R
Article: CEREBRAL CORTEX. 2014;24(4):996-1008
Epileptic synapsin triple knockout mice exhibit progressive long-term aberrant plasticity in the entorhinal cortex.
Ketzef M; Gitler D
Article: PLOS ONE. 2014;9(12):e113841
Adamantyl analogues of paracetamol as potent analgesic drugs via inhibition of TRPA1.
Fresno N; Pérez-Fernández R; Goicoechea C; Alkorta I; Fernández-Carvajal A; de la Torre-Martínez R; Quirce S; Ferrer-Montiel A; Martín MI; Goya P; Elguero J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(40):16223-16228
Clusters of cerebellar Purkinje cells control their afferent climbing fiber discharge
Chaumont J; Guyon N; Valera AM; Dugue GP; Popa D; Marcaggi P; Gautheron V; Reibel-Foisset S; Dieudonne S; Stephan A; Barrot M; Cassel J-C; Dupont J-L; Doussau F; Poulain B; Selimi F; Lena C; Isope P
Article: JOURNAL OF NEUROSCIENCE. 2013;33(18):8045-8054
Dopamine Differentially Modulates the Excitability of Striatal Neurons of the Direct and Indirect Pathways in Lamprey
Ericsson J; Stephenson-Jones M; Perez-Fernandez J; Robertson B; Silberberg G; Grillner S
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(16):E1524-E1532
Neural progenitors organize in small-world networks to promote cell proliferation
Malmersjo S; Rebellato P; Smedler E; Planert H; Kanatani S; Liste I; Nanou E; Sunner H; Abdelhady S; Zhang S; Andang M; El Manira A; Silberberg G; Arenas E; Uhlen P
Article: JOURNAL OF NEUROSCIENCE. 2013;33(15):6552-6556
Functional Role of the Cerebellum in Gamma-Band Synchronization of the Sensory and Motor Cortices
Popa D; Spolidoro M; Proville RD; Guyon N; Belliveau L; Lena C
Article: JOURNAL OF PHYSIOLOGY. 2013;591(4):859-874
Evolutionarily conserved differences in pallial and thalamic short-term synaptic plasticity in striatum
Ericsson J; Stephenson-Jones M; Kardamakis A; Robertson B; Silberberg G; Grillner S
Article: JOURNAL OF NEUROSCIENCE. 2013;33(4):1678-1683
Target Selectivity of Feedforward Inhibition by Striatal Fast-Spiking Interneurons
Szydlowski SN; Dorocic IP; Planert H; Carlen M; Meletis K; Silberberg G
Article: FRONTIERS IN NEURAL CIRCUITS. 2013;7:118
The first mecp2-null zebrafish model shows altered motor behaviors
Pietri T; Roman A-C; Guyon N; Romano SA; Washbourne P; Moens CB; de Polavieja GG; Sumbre G
Article: PLOS ONE. 2013;8(3):e57054
Membrane Properties of Striatal Direct and Indirect Pathway Neurons in Mouse and Rat Slices and Their Modulation by Dopamine
Planert H; Berger TK; Silberberg G
Article: EMBO MOLECULAR MEDICINE. 2012;4(8):730-742
Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice.
Berson A; Barbash S; Shaltiel G; Goll Y; Hanin G; Greenberg DS; Ketzef M; Becker AJ; Friedman A; Soreq H
Article: FRONTIERS IN PSYCHOLOGY. 2012;3:291
Behavioral evidence for differences in social and non-social category learning
Gamond L; Tallon-Baudry C; Guyon N; Lemarechal J-D; Hugueville L; George N
Article: PLOS ONE. 2012;7(4):e30752
A Cortical Attractor Network with Martinotti Cells Driven by Facilitating Synapses
Krishnamurthy P; Silberberg G; Lansner A
Journal article: BMC NEUROSCIENCE. 2011;12(Suppl 1):p187
A cortical attractor network with dynamic synapses
Krishnamurthy P; Silberberg G; Lansner A
Article: NEUROSCIENCE. 2011;189:108-122
Compensatory network alterations upon onset of epilepsy in synapsin triple knock-out mice.
Ketzef M; Kahn J; Weissberg I; Becker AJ; Friedman A; Gitler D
Article: JOURNAL OF PHYSIOLOGY. 2011;589(12):2979-2992
Striatal cellular properties conserved from lampreys to mammals
Ericsson J; Silberberg G; Robertson B; Wikstrom MA; Grillner S
Article: FRONTIERS IN SYSTEMS NEUROSCIENCE. 2011;5:57
Striatal fast-spiking interneurons: from firing patterns to postsynaptic impact.
Klaus A; Planert H; Hjorth JJJ; Berke JD; Silberberg G; Kotaleski JH
Article: FRONTIERS IN BEHAVIORAL NEUROSCIENCE. 2011;5:89
Time determines the neural circuit underlying associative fear learning
Guimarais M; Gregorio A; Cruz A; Guyon N; Moita MA
Article: EMBO JOURNAL. 2010;29(22):3869-3878
Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis
Norberg E; Karlsson M; Korenovska O; Szydlowski S; Silberberg G; Uhlen P; Orrenius S; Zhivotovsky B
Article: PLOS BIOLOGY. 2010;8(9):e1000473
Brief Bursts Self-Inhibit and Correlate the Pyramidal Network
Berger TK; Silberberg G; Perin R; Markram H
Article: JOURNAL OF NEUROSCIENCE. 2010;30(9):3499-3507
Dynamics of Synaptic Transmission between Fast-Spiking Interneurons and Striatal Projection Neurons of the Direct and Indirect Pathways
Planert H; Szydlowski SN; Hjorth JJJ; Grillner S; Silberberg G
Article: JOURNAL OF PHYSIOLOGY. 2009;587(22):5411-5425
Frequency-dependent disynaptic inhibition in the pyramidal network: a ubiquitous pathway in the developing rat neocortex
Berger TK; Perin R; Silberberg G; Markram H
Article: CEREBRAL CORTEX. 2009;19(10):2308-2320
Input Specificity and Dependence of Spike Timing-Dependent Plasticity on Preceding Postsynaptic Activity at Unitary Connections between Neocortical Layer 2/3 Pyramidal Cells
Zilberter M; Holmgren C; Shemer I; Silberberg G; Grillner S; Harkany T; Zilberter Y
Article: FRONTIERS IN COMPUTATIONAL NEUROSCIENCE. 2009;3:27
Multiquantal release underlies the distribution of synaptic efficacies in the neocortex
Loebel A; Silberberg G; Helbig D; Markram H; Tsodyks M; Richardson MJE
Article: JOURNAL OF COMPUTATIONAL NEUROSCIENCE. 2008;25(2):308-316
Slow oscillations in neural networks with facilitating synapses
Melamed O; Barak O; Silberberg G; Markram H; Tsodyks M
Thesis / dissertation: 2008
Extra- and intracellular electronic conductance of signals and its significance for synaptic plasticity
Shemer, Isaac
Review: CURRENT OPINION IN NEUROBIOLOGY. 2008;18(3):332-337
Polysynaptic subcircuits in the neocortex: spatial and temporal diversity
Silberberg G
Article: CEREBRAL CORTEX. 2008;18(4):763-770
Hyperconnectivity of local neocortical microcircuitry induced by prenatal exposure to valproic acid
Rinaldi T; Silberberg G; Markram H
Article: JOURNAL OF NEUROSCIENCE. 2008;28(8):1904-1915
Locomotor deficiencies and aberrant development of subtype-specific GABAergic Interneurons caused by an unliganded thyroid hormone receptor α1
Wallis K; Sjogren M; Van Hogerlinden M; Silberberg G; Fisahn A; Nordstrom K; Larsson L; Westerblad H; De Escobar GM; Shupliakov O; Vennstrom B
Article: JOURNAL OF NEUROPHYSIOLOGY. 2008;99(2):1020-1031
Measurement and analysis of postsynaptic potentials using a novel voltage-deconvolution method
Richardson MJE; Silberberg G
Article: CEREBRAL CORTEX. 2007;17(9):2204-2213
Morphological, electrophysiological, and synaptic properties of corticocallosal pyramidal cells in the neonatal rat neocortex
Le Be J-V; Silberberg G; Wang Y; Markram H
Article: NEURON. 2007;53(5):735-746
Disynaptic inhibition between neocortical pyramidal cells mediated by martinotti cells
Silberberg G; Markram H
Review: TRENDS IN NEUROSCIENCES. 2005;28(10):541-551
Synaptic pathways in neural microcircuits
Silberberg G; Grillner S; LeBeau FEN; Maex R; Markram H
Review: TRENDS IN NEUROSCIENCES. 2005;28(10):525-533
Microcircuits in action - from CPGs to neocortex
Grillner S; Markram H; De Schutter E; Silberberg G; LeBeau FEN
Published conference paper: NEUROCOMPUTING. 2005;65:685-690
Subthreshold cross-correlations between cortical neurons: A reference model with static synapses
Melamed O; Silberberg G; Markram H; Gerstner W; Richardson MJE
Published conference paper: JOURNAL OF COMPUTATIONAL NEUROSCIENCE. 2005;18(3):323-331
Short-term synaptic plasticity orchestrates the response of pyramidal cells and interneurons to population bursts
Richardson MJE; Melamed O; Silberberg G; Gerstner W; Markram H
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(3):880-885
The neocortical microcircuit as a tabula rasa
Kalisman N; Silberberg G; Markram H
Article: JOURNAL OF PHYSIOLOGY. 2004;561(1):65-90
Anatomical, physiological and molecular properties of Martinotti cells in the somatosensory cortex of the juvenile rat
Wang Y; Toledo-Rodriguez M; Gupta A; Wu CZ; Silberberg G; Luo JY; Markram H
Review: NATURE REVIEWS NEUROSCIENCE. 2004;5(10):793-807
Interneurons of the neocortical inhibitory system
Markram H; Toledo-Rodriguez M; Wang Y; Gupta A; Silberberg G; Wu CZ
Article: JOURNAL OF PHYSIOLOGY. 2004;556(1):19-27
Synaptic dynamics control the timing of neuronal excitation in the activated neocortical microcircuit
Silberberg G; Wu CZ; Markram H
Article: JOURNAL OF NEUROPHYSIOLOGY. 2004;91(2):704-709
Dynamics of population rate codes in ensembles of neocortical neurons
Silberberg G; Bethge M; Markram H; Pawelzik K; Tsodyks M
Article: BIOLOGICAL CYBERNETICS. 2003;88(3):210-218
Deriving physical connectivity from neuronal morphology
Kalisman N; Silberberg G; Markram H
Article: TRENDS IN NEUROSCIENCES. 2002;25(5):227-230
Stereotypy in neocortical microcircuits
Silberberg G; Gupta A; Markram H
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Medarbetare och kontakt

Gruppledare

Gilad Silberberg
Professor | Docent
Telefon +46852487345
E-postadress gilad.silberberg@ki.se

Alla medarbetare i gruppen

Joseph Baxendale
Doktorand
E-postadress joseph.baxendale@ki.se
Jingjing Chen
Postdoktorala Studier
E-postadress jingjing.chen@ki.se
Matthijs Dorst
Postdoktor
E-postadress matthijs.dorst@ki.se
Feng Du
Postdoktorala Studier
E-postadress feng.du@ki.se
Ruy Gomez Ocadiz
Postdoktor
E-postadress ruy.gomez.ocadiz@ki.se
Nicolas Gustavo Guyon
Postdoktor
E-postadress nicolas.guyon@ki.se
Yvonne Johansson
Postdoktor
E-postadress yvonne.johansson@ki.se
Maya Ketzef
Biträdande Lektor
E-postadress maya.ketzef@ki.se
Linda Koene
Postdoktor
E-postadress linda.koene@ki.se
Movitz Lenninger
Forskningsassistent
E-postadress movitz.lenninger@ki.se
Alessia Ricci
Doktorand
E-postadress alessia.ricci@ki.se
Inês Santos
Doktorand
E-postadress ines.santos@ki.se
Gilad Silberberg
Professor | Docent
Telefon +46852487345
E-postadress gilad.silberberg@ki.se
Roberto de la Torre Martinez
Forskningsspecialist
E-postadress roberto.de.la.torre.martinez@ki.se

Karolinska Institutet, Biomedicum, Solnavägen 9