Lemmens Group

Publikationer

Utvalda publikationer

• Preprint: BIORXIV. 2025

  Spatial mapping of DNA synthesis reveals dynamics and geometry of human replication nanostructures

  Hawgood M; González BU; Agostinho A; Thiagarajan P; Yang Y; Zhang X; Giglio G; Quijada G; Fonseca M; Bartek J; Blom H; Lemmens B
• Article: JOURNAL OF MEDICINAL CHEMISTRY. 2024;67(11):8609-8629

  Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε

  Gama FHDS; Dutra LA; Hawgood M; dos Reis CV; Serafim RAM; Ferreira Jr MA; Teodoro BVM; Takarada J; Santiago AS; Balourdas D-I; Nilsson A-S; Urien B; Almeida VM; Gileadi C; Ramos PZ; Salmazo A; Vasconcelos SNS; Cunha MR; Mueller S; Knapp S; Massirer KB; Elkins JM; Gileadi O; Mascarello A; Lemmens BBLG; Guimaraes CRW; Azevedo H; Counago RM
• Article: CELL DEATH AND DIFFERENTIATION. 2023;30(7):1666-1678

  Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET

  Kanellis DC; Zisi A; Skrott Z; Lemmens B; Espinoza JA; Kosar M; Bjorkman A; Li X; Arampatzis S; Bartkova J; Andujar-Sanchez M; Fernandez-Capetillo O; Mistrik M; Lindstrom MS; Bartek J
• Article: NUCLEIC ACIDS RESEARCH. 2022;50(11):6235-6250

  THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1

  Kamp JA; Lemmens BBLG; Romeijn RJ; Gonzalez-Prieto R; Olsen JV; Vertegaal ACO; van Schendel R; Tijsterman M
• Article: NATURE COMMUNICATIONS. 2021;12(1):7126

  Helicase Q promotes homology-driven DNA double-strand break repair and prevents tandem duplications.

  Kamp JA; Lemmens BBLG; Romeijn RJ; Changoer SC; van Schendel R; Tijsterman M
• Review: JOURNAL OF CELL BIOLOGY. 2019;218(12):3892-3902

  DNA replication and mitotic entry: A brake model for cell cycle progression

  Lemmens B; Lindqvist A
• Article: MOLECULAR CELL. 2018;71(1):117-128.e3

  DNA Replication Determines Timing of Mitosis by Restricting CDK1 and PLK1 Activation

  Lemmens B; Hegarat N; Akopyan K; Sala-Gaston J; Bartek J; Hochegger H; Lindqvist A
• Article: NATURE COMMUNICATIONS. 2015;6:8909

  Mutagenic consequences of a single G-quadruplex demonstrate mitotic inheritance of DNA replication fork barriers.

  Lemmens B; van Schendel R; Tijsterman M
• Article: PLOS GENETICS. 2013;9(2):e1003276

  COM-1 promotes homologous recombination during Caenorhabditis elegans meiosis by antagonizing Ku-mediated non-homologous end joining.

  Lemmens BBLG; Johnson NM; Tijsterman M
• Article: PLOS GENETICS. 2013;9(3):e1003339

  A role for the malignant brain tumour (MBT) domain protein LIN-61 in DNA double-strand break repair by homologous recombination.

  Johnson NM; Lemmens BBLG; Tijsterman M
• Review: CHROMOSOMA. 2011;120(1):1-21

  DNA double-strand break repair in Caenorhabditis elegans.

  Lemmens BBLG; Tijsterman M
• Article: CURRENT BIOLOGY. 2006;16(19):1950-1955

  Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery.

  Mamely I; van Vugt MA; Smits VAJ; Semple JI; Lemmens B; Perrakis A; Medema RH; Freire R

Medarbetare och kontakt

Gruppledare

• 

  Bennie Lemmens

  Forskare | Biträdande Lektor

  E-postadress bennie.lemmens@ki.se

Alla medarbetare i gruppen

• Giovanni Giglio

  Forskningsassistent

  E-postadress giovanni.giglio@ki.se
• 

  Michael Hawgood

  Doktorand-L

  E-postadress michael.hawgood@ki.se
• 

  Bennie Lemmens

  Forskare | Biträdande Lektor

  E-postadress bennie.lemmens@ki.se
• Bruno Urien

  Doktorand

  E-postadress bruno.urien@ki.se
• Xue Zhang

  Postdoktor

  E-postadress xue.zhang@ki.se