Proteinbiokemi för utveckling av nya medicinska behandlingar – Janne Johanssons forskargrupp

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Article: COMMUNICATIONS BIOLOGY. 2020;3(1):32
Augmentation of Bri2 molecular chaperone activity against amyloid-β reduces neurotoxicity in mouse hippocampus in vitro
Chen G; Andrade-Talavera Y; Tambaro S; Leppert A; Nilsson HE; Zhong X; Landreh M; Nilsson P; Hebert H; Biverstal H; Fisahn A; Abelein A; Johansson J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2019;294(8):2606-2615
Blood-brain and blood-cerebrospinal fluid passage of BRICHOS domains from two molecular chaperones in mice
Tambaro S; Galan-Acosta L; Leppert A; Chen G; Biverstal H; Presto J; Nilsson P; Johansson J
Review: JOURNAL OF INTERNAL MEDICINE. 2019;285(2):165-186
Synthetic surfactants with SP-B and SP-C analogues to enable worldwide treatment of neonatal respiratory distress syndrome and other lung diseases
Johansson J; Curstedt T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2018;115(12):E2752-E2761
BRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cells
Oskarsson ME; Hermansson E; Wang Y; Welsh N; Presto J; Johansson J; Westermark GT
Article: NATURE COMMUNICATIONS. 2017;8(1):2081
Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state
Chen G; Abelein A; Nilsson HE; Leppert A; Andrade-Talavera Y; Tambaro S; Hemmingsson L; Roshan F; Landreh M; Biverstal H; Koeck PJB; Presto J; Hebert H; Fisahn A; Johansson J
Article: NATURE COMMUNICATIONS. 2017;8:15504
Efficient protein production inspired by how spiders make silk
Kronqvist N; Sarr M; Lindqvist A; Nordling K; Otikovs M; Venturi L; Pioselli B; Purhonen P; Landreh M; Biverstal H; Toleikis Z; Sjoberg L; Robinson CV; Pelizzi N; Jornvall H; Hebert H; Jaudzems K; Curstedt T; Rising A; Johansson J
Article: NATURE STRUCTURAL & MOLECULAR BIOLOGY. 2015;22(3):207-213
A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
Cohen SIA; Arosio P; Presto J; Kurudenkandy FR; Biverstal H; Dolfe L; Dunning C; Yang X; Frohm B; Vendruscolo M; Johansson J; Dobson CM; Fisahn A; Knowles TPJ; Linse S
Article: NATURE COMMUNICATIONS. 2014;5:3254
Sequential pH-driven dimerization and stabilization of the N-terminal domain enables rapid spider silk formation
Kronqvist N; Otikovs M; Chmyrov V; Chen G; Andersson M; Nordling K; Landreh M; Sarr M; Jornvall H; Wennmalm S; Widengren J; Meng Q; Rising A; Otzen D; Knight SD; Jaudzems K; Johansson J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(7):2325-2329
High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C
Willander H; Askarieh G; Landreh M; Westermark P; Nordling K; Keranen H; Hermansson E; Hamvas A; Nogee LM; Bergman T; Saenz A; Casals C; Aqvist J; Jornvall H; Berglund H; Presto J; Knight SD; Johansson J
Article: NATURE. 2010;465(7295):236-U125
Self-assembly of spider silk proteins is controlled by a pH-sensitive relay
Askarieh G; Hedhammar M; Nordling K; Saenz A; Casals C; Rising A; Johansson J; Knight SD
Article: PROTEIN SCIENCE. 1998;7(12):2533-2540
Pulmonary surfactant-associated polypeptide C in a mixed organic solvent transforms from a monomeric α-helical state into insoluble β-sheet aggregates
Szyperski T; Vandenbussche G; Curstedt T; Ruysschaert JM; Wüthrich K; Johansson J

Proteinbiokemi för utveckling av nya medicinska behandlingar – Janne Johanssons forskargrupp

Janne Johansson

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