Ninib Baryawno forskargrupp

Vår forskning

Stöd forskning inom Institutionen för Kvinnor och barns hälsa

Foto: -

Ninib Baryawno forskargrupp

Stöd forskning inom Institutionen för Kvinnor och barns hälsa

För att ge din gåva via Swish, följ anvisningarna nedan:

Ange mottagare Swish-nummer: 123 066 26 84

Ange valfritt belopp

Viktigt! I fältet för meddelande ange forskargruppsledare (Baryawno) för det forskningsområde du vill stödja annars går ditt stöd som en allmän donation till vår forskning inom Kvinnor och barns hälsa.

Swisha, klar!

Publikationer

Alla gruppmedlemmars publikationer

Article: CANCER LETTERS. 2025;625:217769
Gain of chromosome 17 is an early genetic abnormality in neuroblastoma with PPM1D emerging as a strong candidate oncogene driving tumor progression
Milosevic J; Fransson S; Svensson J; Otte J; Olsen TK; Sveinbjornsson B; Hertwig F; Bartenhagen C; Abel F; Reinsbach SE; Djos A; Javanmardi N; Shi Y; Hehir-Kwa JY; Mensenkamp A; Tytgat GAM; Holmberg J; Molenaar JJ; Jongmans M; Fischer M; Baryawno N; Gisselsson D; Martinsson T; Kogner P; Johnsen JI
Article: MOLECULAR CANCER RESEARCH. 2025;23(7):653-665
Single-Cell and Spatial Transcriptomics Reveal a Tumor-Associated Macrophage Subpopulation that Mediates Prostate Cancer Progression and Metastasis
Mei S; Zhang H; Hirz T; Jeffries NE; Xu Y; Baryawno N; Wu S; Wu C-L; Patnaik A; Saylor PJ; Sykes DB; Dahl DM
Article: PLOS ONE. 2025;20(4):e0321020
Solute carrier family 2 member 2 (glucose transporter 2): a common factor of hepatocyte and hepatocellular carcinoma differentiation
Kim Y; Yeuni Y; Heo HJ; Kim ES; Myung K; Baryawno N; Kim YH; Oh C-K
Doctoral thesis: 2025
Delineating cellular heterogeneity of neuroblastoma for identifying therapeutically targetable vulnerabilities
Embaie BT
Article: CANCER RESEARCH. 2025;85(6):1015-1034
Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell State
Embaie BT; Sarkar H; Alchahin AM; Otte J; Olsen TK; Tummler C; Kameneva P; Artemov AV; Akkuratova N; Adameyko I; Stukenborg J-B; Wickstrom M; Kogner P; Johnsen JI; Mei S; Kharchenko PV; Baryawno N
Doctoral thesis: 2025
Characterization of the immune cell landscape in neuroblastoma : for the discovery of novel therapeutics
Verhoeven M
Article: PLOS ONE. 2025;20(1):e0315981
Uncovering NK cell sabotage in gut diseases via single cell transcriptomics
Lee H; Ko DS; Heo HJ; Baek SE; Kim EK; Kwon EJ; Kang J; Yu Y; Baryawno N; Kim K; Lee D; Kim YH
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2024;741:151075
ERRα is dispensable for hematopoietic stem cell function in the bone marrow
Bae HE; Baryawno N; Kim BS; Yoon S; Oh S-O; Jo E-K; Kim CD; Lee D
Article: CANCERS. 2024;16(24):4162
DHODH Inhibition Suppresses MYC and Inhibits the Growth of Medulloblastoma in a Novel In Vivo Zebrafish Model
Tsea I; Olsen TK; Polychronopoulos PA; Tummler C; Sykes DB; Baryawno N; Dyberg C
Journal article: NEURO-ONCOLOGY ADVANCES. 2024;6(1):vdae172
Genomic tumor evolution dictates human medulloblastoma progression
Ruchiy Y; Tsea I; Preka E; Verhoeven BM; Olsen TK; Mei S; Sinha I; Blomgren K; Carlson L-M; Dyberg C; Johnsen JI; Baryawno N
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024;25(19):10517
27-Hydroxycholesterol Negatively Affects the Function of Bone Marrow Endothelial Cells in the Bone Marrow
Woo S-Y; Shim W-S; Lee H; Baryawno N; Song P; Kim BS; Yoon S; Oh S-O; Lee D
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024;25(19):10381
Blockade of mTORC1 via Rapamycin Suppresses 27-Hydroxycholestrol-Induced Inflammatory Responses
Kang N; Kim J; Kwon M; Son Y; Eo S-K; Baryawno N; Kim BS; Yoon S; Oh S-O; Lee D; Kim K
Article: JOURNAL OF CLINICAL INVESTIGATION. 2024;134(21):e175310
Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastoma
Nagarajan D; Parracho RT; Corujo D; Xie M; Kutkaite G; Olsen TK; Bedos MR; Salehi M; Baryawno N; Menden MP; Chen X; Buschbeck M; Mao Y
Journal article: CANCER RESEARCH. 2024;84(17):b060
Clonal composition of αβ and γδ T cells in primary human neuroblastoma tumors - Is every child unique?
Verhoeven BM; Ye K; Stenman J; Kogner P; Johnsen JI; Reina OB; Kreslavskiy T; Baryawno N
Article: CANCER RESEARCH COMMUNICATIONS. 2024;4(9):2553-2564
Long-Lasting Response to Lorlatinib in Patients with ALK-Driven Relapsed or Refractory Neuroblastoma Monitored with Circulating Tumor DNA Analysis
Ek T; Ibrahim RR; Vogt H; Georgantzi K; Trager C; Gaarder J; Djos A; Rahmqvist I; Mellstroem E; Pujol-Calderon F; Vannas C; Hansson L; Fagman H; Treis D; Fransson S; Osterlund T; Chuang T-P; Verhoeven BM; Stahlberg A; Palmer RH; Hallberg B; Martinsson T; Kogner P; Dalin M
Article: MOLECULAR CANCER. 2024;23(1):180
Joint single-cell genetic and transcriptomic analysis reveal pre-malignant SCP-like subclones in human neuroblastoma
Olsen TK; Otte J; Mei S; Embaie BT; Kameneva P; Cheng H; Gao T; Zachariadis V; Tsea I; Bjorklund A; Kryukov E; Hou Z; Johansson A; Sundstrom E; Martinsson T; Fransson S; Stenman J; Fard SS; Johnsen JI; Kogner P; Adameyko I; Enge M; Kharchenko PV; Baryawno N
Article: JCI INSIGHT. 2024;9(6):e173337
Single-cell analyses of metastatic bone marrow in human neuroblastoma reveals microenvironmental remodeling and metastatic
Mei S; Alchahin AM; Embaie BT; Gavriliuc IM; Verhoeven BM; Zhao T; Li X; Jeffries NE; Pepich A; Sarkar H; Olsen TK; Wickstrom M; Stenman J; Reina-Bedoya O; Kharchenko PV; Saylor PJ; Johnsen JI; Sykes DB; Kogner P; Baryawno N
Article: CANCER CELL. 2024;42(2):283-300.e8
Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy
Wienke J; Visser LL; Kholosy WM; Keller KM; Barisa M; Poon E; Munnings-Tomes S; Himsworth C; Calton E; Rodriguez A; Bernardi R; Ham FVD; Hooff SRV; Matser YAH; Tas ML; Langenberg KPS; Lijnzaad P; Borst AL; Zappa E; Bergsma FJ; Strijker JGM; Verhoeven BM; Mei S; Kramdi A; Restuadi R; Sanchez-Bernabeu A; Cornel AM; Holstege FCP; Gray JC; Tytgat GAM; Scheijde-Vermeulen MA; Wijnen MHWA; Dierselhuis MP; Straathof K; Behjati S; Wu W; Heck AJR; Koster J; Nierkens S; Janoueix-Lerosey I; Krijger RRD; Baryawno N; Chesler L; Anderson J; Caron HN; Margaritis T; Noesel MMV; Molenaar JJ
Article: JOURNAL OF NUCLEAR MEDICINE. 2024;65(2):294-299
Noninvasive PET Detection of CD69-Positive Immune Cells Before Signs of Clinical Disease in Inflammatory Arthritis
Puuvuori E; Shen Y; Hulsart-Billstrom G; Mitran B; Zhang B; Cheung P; Wegrzyniak O; Ingvast S; Persson J; Stahl S; Korsgren O; Lofblom J; Wermeling F; Eriksson O
Article: GENOME MEDICINE. 2024;16(1):1
Single-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions
Mei S; Alchahin AM; Tsea I; Kfoury Y; Hirz T; Jeffries NE; Zhao T; Xu Y; Zhang H; Sarkar H; Wu S; Subtelny AO; Johnsen JI; Zhang Y; Salari K; Wu C-L; Randolph MA; Scadden DT; Dahl DM; Shin J; Kharchenko PV; Saylor PJ; Sykes DB; Baryawno N
Article: NEURO-ONCOLOGY ADVANCES. 2024;6(1):vdae172
Genomic tumor evolution dictates human medulloblastoma progression.
Ruchiy Y; Tsea I; Preka E; Verhoeven BM; Olsen TK; Mei S; Sinha I; Blomgren K; Carlson L-M; Dyberg C; Johnsen JI; Baryawno N
Article: ONCOIMMUNOLOGY. 2023;12(1):2184130
Macrophage infiltration promotes regrowth in MYCN-amplified neuroblastoma after chemotherapy
Valind A; Verhoeven BM; Enoksson J; Karlsson J; Christensson G; Manas A; Aaltonen K; Jansson C; Bexell D; Baryawno N; Gisselsson D; Hagerling C
Review: CANCERS. 2023;15(19):4734
Recent Advances in Single-Cell RNA-Sequencing of Primary and Metastatic Clear Cell Renal Cell Carcinoma
Alchahin AM; Tsea I; Baryawno N
Article: JCI INSIGHT. 2023;8(17):e167858
Adult Prg4+ progenitors repair long-term articular cartilage wounds in vivo.
Massengale M; Massengale JL; Benson CR; Baryawno N; Oki T; Steinhauser ML; Wang A; Balani D; Oh LS; Randolph MA; Gill TJ; Kronenberg HM; Scadden DT
Article: JOURNAL OF NUCLEAR MEDICINE. 2023;64(3):423-429
PET Imaging of Neutrophil Elastase with 11C-GW457427 in Acute Respiratory Distress Syndrome in Pigs
Puuvuori E; Chiodaroli E; Estrada S; Cheung P; Lubenow N; Sigfridsson J; Romelin H; Ingvast S; Elgland M; Liggieri F; Korsgren O; Perchiazzi G; Eriksson O; Antoni G
Article: NATURE COMMUNICATIONS. 2023;14(1):663
Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses
Hirz T; Mei S; Sarkar H; Kfoury Y; Wu S; Verhoeven BM; Subtelny AO; Zlatev DV; Wszolek MW; Salari K; Murray E; Chen F; Macosko EZ; Wu C-L; Scadden DT; Dahl DM; Baryawno N; Saylor PJ; Kharchenko PV; Sykes DB
Conference publication: PEDIATRIC BLOOD & CANCER. 2022;69:S211-S212
SINGLE CELL ANALYSIS OF HUMAN BONE METASTATIC NEUROBLASTOMA UNRAVELS EMERGING IMMUNE CELL POPULATIONS IN THE BONE MARROW
Alchahin A; Embaie BT; Mei S; Verhoeven BM; Olsen T; Kharchenko P; Johnsen JI; Kogner P; Baryawno N
Conference publication: PEDIATRIC BLOOD & CANCER. 2022;69:S215
SINGLE-CELL TRANSCRIPTOMICS REVEAL TUMOR CELL DIVERSITY IN NEUROBLASTOMA TRANSGENIC MOUSE AND ORGANOID MODELS
Embaie BT; Sarkar H; Alchahin A; Otte J; Olsen T; Mei S; Kharchenko P; Baryawno N
Conference publication: PEDIATRIC BLOOD & CANCER. 2022;69:S226
SCHWANN CELL PRECURSORS IS THE CELL-OF-ORIGIN IN HUMAN NEUROBLASTOMA
Otte J; Olsen T; Mei S; Kameneva P; Embaie BT; Bjorklund A; Johansson A; Sundstrom E; Martinsson T; Fransson S; Stenman J; Cheng H; Zachariadis V; Enge M; Johnsen JI; Kogner P; Adameyko I; Kharchenko P; Baryawno N
Conference publication: PEDIATRIC BLOOD & CANCER. 2022;69:S229-S230
INVESTIGATING THE INTERACTIONS OF DISTINCT TUMOR SUBPOPULATIONS IN HUMAN NEUROBLASTOMA USING SINGLE-CELL RNASEQ AND NOVEL SPATIAL MULTI-OMICS
Tsea I; Olsen T; Otte J; Mei S; Embaie BT; Kogner P; Johnsen JI; Baryawno N; Fard S
Article: CELL DEATH & DISEASE. 2022;13(10):916
Role of reactive oxygen species in regulating 27-hydroxycholesterol-induced apoptosis of hematopoietic progenitor cells and myeloid cell lines
Woo S-Y; Lee H; Park SM; Choi H-S; Kim J; Kwon M; Sohn J; Nam JH; Kim H-S; Song P; Baryawno N; Kim Y-H; Kim K; Lee D
Article: NATURE COMMUNICATIONS. 2022;13(1):5747
A transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma
Alchahin AM; Mei S; Tsea I; Hirz T; Kfoury Y; Dahl D; Wu C-L; Subtelny AO; Wu S; Scadden DT; Shin JH; Saylor PJ; Sykes DB; Kharchenko PV; Baryawno N
Book chapter: NANOTECHNOLOGY FOR DIABETES MANAGEMENT. 2022;p. 262-291
In Vivo Imaging of the Pancreas and Gut Hormone Receptors
Eriksson O; Hulsart-Billström G; Mitran B; Puuvuori E; Velikyan I
Article: JCI INSIGHT. 2022;7(17):e153836
DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma
Olsen TK; Dyberg C; Embaie BT; Alchahin A; Milosevic J; Ding J; Otte J; Tummler C; Myrberg IH; Westerhout EM; Koster J; Versteeg R; Ding H-F; Kogner P; Johnsen JI; Sykes DB; Baryawno N
Preprint: BIORXIV. 2022
A new transcriptional metastatic signature predicts survival in clear cell renal cell carcinoma
Alchahin AM; Mei S; Tsea I; Hirz T; Kfoury Y; Dahl D; Wu C-L; Subtelny AO; Wu S; Scadden DT; Shin JH; Saylor PJ; Sykes DB; Kharchenko PV; Baryawno N
Article: CELL REPORTS MEDICINE. 2022;3(6):100657
The immune cell atlas of human neuroblastoma
Verhoeven BM; Mei S; Olsen TK; Gustafsson K; Valind A; Lindstrom A; Gisselsson D; Fard SS; Hagerling C; Kharchenko PV; Kogner P; Johnsen JI; Baryawno N
Conference publication: CANCER RESEARCH. 2022;82(12)
Single-cell landscape of the TH-MYCN neuroblastoma mouse model
Embaie BT; Alchahin A; Olsen TK; Sarkar H; Mei S; Baryawno N
Conference publication: CANCER RESEARCH. 2022;82(12)
Transcriptomic landscape of medulloblastoma reveals pathways of tumor-stroma remodelling
Tsea I; Ruchiy Y; Verhoeven M; Sinha I; Blomgren K; Carlson LM; Johnsen JI; Dyberg C; Baryawno N
Journal article: CANCER RESEARCH. 2022;82(12_Supplement):1677
Abstract 1677: Transcriptomic landscape of medulloblastoma reveals pathways of tumor-stroma remodelling
Tsea I; Ruchiy Y; Verhoeven M; Sinha I; Blomgren K; Carlson LM; Johnsen JI; Dyberg C; Baryawno N
Article: SCIENTIFIC REPORTS. 2022;12(1):7519
Oxime derivative TFOBO promotes cell death by modulating reactive oxygen species and regulating NADPH oxidase activity in myeloid leukemia
Jo A; Kwak J-H; Woo S-Y; Kim B-Y; Son Y; Choi H-S; Kim J; Kwon M; Cho H-R; Eo S-K; Nam JH; Kim H-S; Baryawno N; Lee D; Kim K
Journal article: EJNMMI RESEARCH. 2022;12(1):19
PET-CT imaging of pulmonary inflammation using [⁶⁸Ga]Ga-DOTA-TATE
Puuvuori E; Liggieri F; Velikyan I; Chiodaroli E; Sigfridsson J; Romelin H; Ingvast S; Korsgren O; Hulsart-Billstrom G; Perchiazzi G; Eriksson O
Article: AMERICAN JOURNAL OF CANCER RESEARCH. 2022;12(12):5532-5551
Original Risk stratification of patients with right-sided colorectal cancer based on the tumor-infiltrating M1 macrophage
Lim DM; Kang J; Woo S-Y; Choi H-S; Kwon M; Kim J; Park HR; Jung K; Baryawno N; Kim H-S; Lee D; Kim YH
Journal article: SCIENTIFIC REPORTS. 2021;11(1):24466
Potential of [¹¹C]UCB-J as a PET tracer for islets of Langerhans
Puuvuori E; Rokka J; Carlsson P-O; Li Z; Eriksson J; Eriksson O
Article: ELIFE. 2021;10:e66512
External signals regulate continuous transcriptional states in hematopoietic stem cells
Fast EM; Sporrij A; Manning M; Rocha EL; Yang S; Zhou Y; Guo J; Baryawno N; Barkas N; Scadden D; Camargo F; Zon LI
Article: CANCER CELL. 2021;39(11):1464-1478.e8
Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment
Kfoury Y; Baryawno N; Severe N; Mei S; Gustafsson K; Hirz T; Brouse T; Scadden EW; Igolkina AA; Kokkaliaris K; Choi BD; Barkas N; Randolph MA; Shin JH; Saylor PJ; Scadden DT; Sykes DB; Kharchenko PV
Conference publication: PEDIATRIC BLOOD & CANCER. 2021;68:S224-S225
Single-Cell Transcriptomic Landscape of Transgenic Mouse Model of Neuroblastoma
Embaie BT; Alchahin A; Olsen T; Mei S; Gavriliuc I; Baryawno N
Article: CANCERS. 2021;13(21):5493
High Expression of PPM1D Induces Tumors Phenotypically Similar to TP53 Loss-of-Function Mutations in Mice
Milosevic J; Fransson S; Gulyas M; Olsen TK; Gallo-Oller G; Treis D; Elfman LHM; Wilhelm M; Martinsson T; Baryawno N; Kogner P; Johnsen JI
Journal article: SCIENTIFIC REPORTS. 2021;11(1):19151
Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69
Persson J; Puuvuori E; Zhang B; Velikyan I; Aberg O; Muller M; Nygren P-A; Stahl S; Korsgren O; Eriksson O; Lofblom J
Article: NATURE METHODS. 2021;18(8):912-920
An unsupervised method for physical cell interaction profiling of complex tissues
Andrews N; Serviss JT; Geyer N; Andersson AB; Dzwonkowska E; Sutevski I; Heijboer R; Baryawno N; Gerling M; Enge M
Article: NATURE GENETICS. 2021;53(5):694-706
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin
Kameneva P; Artemov AV; Kastriti ME; Faure L; Olsen TK; Otte J; Erickson A; Semsch B; Andersson ER; Ratz M; Frisen J; Tischler AS; de Krijger RR; Bouderlique T; Akkuratova N; Vorontsova M; Gusev O; Fried K; Sundstrom E; Mei S; Kogner P; Baryawno N; Kharchenko PV; Adameyko I
Article: BIOMEDICINES. 2021;9(4):434
PET Imaging of GPR44 by Antagonist [¹¹C]MK-7246 in Pigs
Cheung P; Zhang B; Puuvuori E; Estrada S; Amin MA; Ye S; Korsgren O; Odell LR; Eriksson J; Eriksson O
Journal article: BMJ OPEN DIABETES RESEARCH & CARE. 2021;9(1):e002083
Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography
Manell E; Puuvuori E; Svensson A; Velikyan I; Hulsart-Billstrom G; Hedenqvist P; Holst JJ; Waern MJ; Eriksson O
Review: FRONTIERS IN ONCOLOGY. 2021;10:624079
MYCN Function in Neuroblastoma Development
Otte J; Dyberg C; Pepich A; Johnsen JI
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2020;117(49):31386-31397
Capillary leakage provides nutrients and antioxidants for rapid pneumococcal proliferation in influenza-infected lower airways
Sender V; Hentrich K; Pathak A; Ler ATQ; Embaie BT; Lundstrom SL; Gaetani M; Bergstrand J; Nakamoto R; Sham L-T; Widengren J; Normark S; Henriques-Normark B
Article: CLINICAL CANCER RESEARCH. 2020;26(21):5747-5758
The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia.
Verbeke D; Demeyer S; Prieto C; de Bock CE; De Bie J; Gielen O; Jacobs K; Mentens N; Verhoeven BM; Uyttebroeck A; Boeckx N; De Keersmaecker K; Maertens J; Segers H; Cools J
Article: BLOOD. 2020;136(11):1303-1316
Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers.
Yusuf RZ; Saez B; Sharda A; van Gastel N; Yu VWC; Baryawno N; Scadden EW; Acharya S; Chattophadhyay S; Huang C; Viswanathan V; S'aulis D; Cobert J; Sykes DB; Keibler MA; Das S; Hutchinson JN; Churchill M; Mukherjee S; Lee D; Mercier F; Doench J; Bullinger L; Logan DJ; Schreiber S; Stephanopoulos G; Rizzo WB; Scadden DT
Article: CELL METABOLISM. 2020;32(3):391-403.e6
Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance
van Gastel N; Spinelli JB; Sharda A; Schajnovitz A; Baryawno N; Rhee C; Oki T; Grace E; Soled HJ; Milosevic J; Sykes DB; Hsu PP; Vander Heiden MG; Vidoudez C; Trauger SA; Haigis MC; Scadden DT
Article: NATURE. 2020;579(7797):111-117
Lipid availability determines fate of skeletal progenitor cells via SOX9
van Gastel N; Stegen S; Eelen G; Schoors S; Carlier A; Daniels VW; Baryawno N; Przybylski D; Depypere M; Stiers P-J; Lambrechts D; Van Looveren R; Torrekens S; Sharda A; Agostinis P; Lambrechts D; Maes F; Swinnen JV; Geris L; Van Oosterwyck H; Thienpont B; Carmeliet P; Scadden DT; Carmeliet G
Article: SCIENTIFIC REPORTS. 2019;9(1):17365
FGF Signalling in the Self-Renewal of Colon Cancer Organoids.
Otte J; Dizdar L; Behrens B; Goering W; Knoefel WT; Wruck W; Stoecklein NH; Adjaye J
Article: CELL STEM CELL. 2019;25(4):570-583.e7
Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping
Severe N; Karabacak NM; Gustafsson K; Baryawno N; Courties G; Kfoury Y; Kokkaliaris KD; Rhee C; Lee D; Scadden EW; Garcia-Robledo JE; Brouse T; Nahrendorf M; Toner M; Scadden DT
Article: CANCERS. 2019;11(9):E1371-1371
Bispecific GRPR-Antagonistic Anti-PSMA/GRPR Heterodimer for PET and SPECT Diagnostic Imaging of Prostate Cancer
Mitran B; Varasteh Z; Abouzayed A; Rinne SS; Puuvuori E; De Rosa M; Larhed M; Tolmachev V; Orlova A; Rosenstrom U
Article: CELL. 2019;177(7):1915-1932.e16
A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia
Baryawno N; Przybylski D; Kowalczyk MS; Kfoury Y; Severe N; Gustafsson K; Kokkaliaris KD; Mercier F; Tabaka M; Hofree M; Dionne D; Papazian A; Lee D; Ashenberg O; Subramanian A; Vaishnav ED; Rozenblatt-Rosen O; Regev A; Scadden DT
Article: BRITISH JOURNAL OF DERMATOLOGY. 2019;180(5):1150-1160
Gene expression profiling in aggressive digital papillary adenocarcinoma sheds light on the architecture of a rare sweat gland carcinoma.
Surowy HM; Giesen AK; Otte J; Büttner R; Falkenstein D; Friedl H; Meier F; Petzsch P; Wachtmeister T; Westphal D; Wieczorek D; Wruck W; Adjaye J; Rütten A; Redler S
Article: STEM CELL RESEARCH & THERAPY. 2019;10(1):100
Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature.
Spitzhorn L-S; Megges M; Wruck W; Rahman MS; Otte J; Degistirici Ö; Meisel R; Sorg RV; Oreffo ROC; Adjaye J
Article: CANCER RESEARCH. 2018;78(18):5300-5314
Modulating Bone Marrow Hematopoietic Lineage Potential to Prevent Bone Metastasis in Breast Cancer
Ubellacker JM; Baryawno N; Severe N; DeCristo MJ; Sceneay J; Hutchinson JN; Haider M-T; Rhee CS; Qin Y; Gregory WM; Garrido-Castro AC; Holen I; Brown JE; Coleman RE; Scadden DT; McAllister SS
Article: GENOME BIOLOGY. 2018;19(1):78
dropEst: pipeline for accurate estimation of molecular counts in droplet-based single-cell RNA-seq experiments
Petukhov V; Guo J; Baryawno N; Severe N; Scadden DT; Samsonova MG; Kharchenko PV
Journal article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(6):2651
Bone marrow drives central nervous system regeneration after radiation injury (vol 128, pg 281, 2018)
Dietrich J; Baryawno N; Nayyar N; Valtis YK; Yang B; Ly I; Besnard A; Severe N; Gustafsson KU; Andronesi OC; Batchelor TT; Sahay A; Scadden DT
Journal article: NEUROLOGY. 2018;90(15_supplement)
Bone Marrow is a Critical Mediator of Central Nervous System Regeneration after Radiation Injury (S23.003)
Dietrich J; Baryawno N; Nayyar N; Valtis Y; Yang B; Ly I; Besnard A; Severe N; Gustafsson K; Andronesi O; Batchelor T; Sahay A; Scadden D
Article: CURRENT PROTOCOLS IN MOLECULAR BIOLOGY. 2018;122(1):e57
Introduction to Single-Cell RNA Sequencing.
Olsen TK; Baryawno N
Article: CELL. 2018;172(1-2):191-204.e10
Rapid Mobilization Reveals a Highly Engraftable Hematopoietic Stem Cell
Hoggatt J; Singh P; Tate TA; Chou B-K; Datari SR; Fukuda S; Liu L; Kharchenko PV; Schajnovitz A; Baryawno N; Mercier FE; Boyer J; Gardner J; Morrow DM; Scadden DT; Pelus LM
Article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(1):281-293
Bone marrow drives central nervous system regeneration after radiation injury
Dietrich J; Baryawno N; Nayyar N; Valtis YK; Yang B; Ly I; Besnard A; Severe N; Gustafsson KU; Andronesi OC; Batchelor TT; Sahay A; Scadden DT
Article: SCIENCE. 2017;358(6367):eaal5081
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecF^high neutrophils
Engblom C; Pfirschke C; Zilionis R; Martins JDS; Bos SA; Courties G; Rickelt S; Severe N; Baryawno N; Faget J; Savova V; Zemmour D; Kline J; Siwicki M; Garris C; Pucci F; Liao H-W; Lin Y-J; Newton A; Yaghi OK; Iwamoto Y; Tricot B; Wojtkiewicz GR; Nahrendorf M; Cortez-Retamozo V; Meylan E; Hynes RO; Demay M; Klein A; Bredella MA; Scadden DT; Weissleder R; Pittet MJ
Review: FEBS LETTERS. 2017;591(15):2226-2240
New insights into human primordial germ cells and early embryonic development from single-cell analysis.
Otte J; Wruck W; Adjaye J
Editorial comment: CELL STEM CELL. 2017;20(5):590-592
Hematopoiesis: Reconciling Historic Controversies about the Niche
Baryawno N; Severe N; Scadden DT
Article: JOURNAL OF CLINICAL INVESTIGATION. 2017;127(4):1405-1413
Amino acid-insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells
Kalaitzidis D; Lee D; Efeyan A; Kfoury Y; Nayyar N; Sykes DB; Mercier FE; Papazian A; Baryawno N; Victora GD; Neuberg D; Sabatini DM; Scadden DT
Journal article: CELL. 2017;168(5):944-945
Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells (vol 167, pg 1310, 2016)
Yu VWC; Yusuf RZ; Oki T; Wu J; Saez B; Wang X; Cook C; Baryawno N; Ziller MJ; Lee E; Gu H; Meissner A; Lin CP; Kharchenko PV; Scadden DT
Journal article: BLOOD. 2016;128(22):430
Distinct Stress Responses of Bone Marrow Stromal Cell Subgroups Defined by Unbiased Single-Cell Mass-Cytometry Analysis
Severe N; Karabacak M; Baryawno N; Gustafsson K; Kfoury YS; Toner M; Scadden DT
Article: CELL. 2016;167(5):1310-1322.e17
Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells
Yu VWC; Yusuf RZ; Oki T; Wu J; Saez B; Wang X; Cook C; Baryawno N; Ziller MJ; Lee E; Gu H; Meissner A; Lin CP; Kharchenko PV; Scadden DT
Article: CELL STEM CELL. 2016;19(4):530-543
Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators
Silberstein L; Goncalves KA; Kharchenko PV; Turcotte R; Kfoury Y; Mercier F; Baryawno N; Severe N; Bachand J; Spencer JA; Papazian A; Lee D; Chitteti BR; Srour EF; Hoggatt J; Tate T; Lo Celso C; Ono N; Nutt S; Heino J; Sipila K; Shioda T; Osawa M; Lin CP; Hu G-F; Scadden DT
Article: MOLECULAR & CELLULAR ONCOLOGY. 2016;3(2):e1131356
Wingless/β-catenin signaling as a modulator of chemoresistance in cancer
Johnsen JI; Wickstrom M; Baryawno N
Article: NATURE COMMUNICATIONS. 2015;6:8904
Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance
Wickstrom M; Dyberg C; Milosevic J; Einvik C; Calero R; Sveinbjornsson B; Sanden E; Darabi A; Siesjo P; Kool M; Kogner P; Baryawno N; Johnsen JI
Article: BMC GENOMICS. 2015;16:925
Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells.
Mertes F; Lichtner B; Kuhl H; Blattner M; Otte J; Wruck W; Timmermann B; Lehrach H; Adjaye J
Review: COCHRANE DATABASE OF SYSTEMATIC REVIEWS. 2015;2015(5):CD009863
Water infusion versus air insufflation for colonoscopy.
Hafner S; Zolk K; Radaelli F; Otte J; Rabenstein T; Zolk O
Journal article: CELL RESEARCH. 2014;24(10):1151-1152
Blood loses it when nerves go bad
Baryawno N; Scadden DT
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2014;450(4):1600-1605
Effects of epigenetic modificators in combination with small molecule inhibitors of receptor tyrosine kinases on medulloblastoma growth
Marino A-M; Frijhoff J; Calero R; Baryawno N; Ostman A; Johnsen JI
Article: INTERNATIONAL JOURNAL OF CANCER. 2013;133(10):2351-2361
Frequent detection of human cytomegalovirus in neuroblastoma: A novel therapeutic target?
Wolmer-Solberg N; Baryawno N; Rahbar A; Fuchs D; Odeberg J; Taher C; Wilhelmi V; Milosevic J; Mohammad A-A; Martinsson T; Sveinbjornsson B; Johnsen JI; Kogner P; Soederberg-Naucler C
Article: INTERNATIONAL JOURNAL OF CANCER. 2013;132(7):1516-1524
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo
Wickstrom M; Dyberg C; Shimokawa T; Milosevic J; Baryawno N; Fuskevag OM; Larsson R; Kogner P; Zaphiropoulos PG; Johnsen JI
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2013;42(4):1239-1248
Expression of TWEAK/Fn14 in neuroblastoma: Implications in tumorigenesis
Pettersen I; Baryawno N; Abel F; Bakkelund WH; Zykova SN; Winberg J-O; Moens U; Rasmuson A; Kogner P; Johnsen JI; Sveinbjornsson B
Article: ONCOTARGET. 2011;2(12):1329-1338
Is human cytomegalovirus a target in cancer therapy?
Johnsen JI; Baryawno N; Soderberg-Naucler C
Article: INTERNATIONAL JOURNAL OF CANCER. 2011;129(12):2958-2965
Effects of small molecule inhibitors of PI3K/Akt/mTOR signaling on neuroblastoma growth in vitro and in vivo
Segerstrom L; Baryawno N; Sveinbjornsson B; Wickstrom M; Elfman L; Kogner P; Johnsen JI
Article: JOURNAL OF CLINICAL INVESTIGATION. 2011;121(10):4043-4055
Detection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic target
Baryawno N; Rahbar A; Wolmer-Solberg N; Taher C; Odeberg J; Darabi A; Khan Z; Sveinbjornsson B; Fuskevag O-M; Segerstrom L; Nordenskjold M; Siesjo P; Kogner P; Johnsen JI; Soderberg-Naucler C
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011;411(1):208-212
Enhanced effects by 4-phenylbutyrate in combination with RTK inhibitors on proliferation in brain tumor cell models
Marino A-M; Sofiadis A; Baryawno N; Johnsen JI; Larsson C; Vukojevic V; Ekstrom TJ
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2011;38(3):843-849
Differential forms of p53 in medulloblastoma primary tumors, cell lines and xenografts
Philipova T; Baryawno N; Hartmann W; Pietsch T; Drud H; Johnsen JI; Ekstrom TJ
Article: CELL CYCLE. 2010;9(13):2548-2554
Medulloblastoma A disease with disorganized developmental signaling cascades
Baryawno N; Sveinbjornsson B; Kogner P; Johnsen JI
Doctoral thesis: 2010
New potential targets in medulloblastoma therapy : studies on cellular mechanisms and mediators
Baryawno N
Article: CANCER RESEARCH. 2010;70(1):266-276
Small-Molecule Inhibitors of Phosphatidylinositol 3-Kinase/Akt Signaling Inhibit Wnt/β-Catenin Pathway Cross-Talk and Suppress Medulloblastoma Growth
Baryawno N; Sveinbjornsson B; Eksborg S; Chen C-S; Kogner P; Johnsen JI
Article: NEURO-ONCOLOGY. 2008;10(5):661-674
Tumor-growth-promoting cyclooxygenase-2 prostaglandin E₂ pathway provides medulloblastoma therapeutic targets
Baryawno N; Sveinbjornsson B; Eksborg S; Orrego A; Segerstrom L; Oqvist CO; Holm S; Gustavsson B; Kagedal B; Kogner P; Johnsen JI
Article: FASEB JOURNAL. 2008;22(10):3525-3536
Expression of enzymes and receptors of the leukotriene pathway in human neuroblastoma promotes tumor survival and provides a target for therapy
Sveinbjornsson B; Rasmuson A; Baryawno N; Wan M; Pettersen I; Ponthan F; Orrego A; Haeggstrom JZ; Johnsen JI; Kogner P
Visa fler

Ninib Baryawno forskargrupp

Vår forskning

Publikationer

Alla gruppmedlemmars publikationer

Finansiering

Medarbetare och kontakt

Gruppledare

Alla medarbetare i gruppen

Ninib Baryawno forskargrupp

Vår forskning

Stöd forskning inom Institutionen för Kvinnor och barns hälsa

Publikationer

Alla gruppmedlemmars publikationer

Finansiering

Medarbetare och kontakt

Gruppledare

Alla medarbetare i gruppen

Träffa oss