Florian Rosenbergers forskargrupp

We seek to understand how mitochondria contribute to disease across cell types. What are the principal mitochondrial disease signatures? How do they differ across biological perturbations? To answer these questions, we apply spatial single-cell proteomics by mass spectrometry to unfold proteomes one cell at a time.

Publikationer
Medarbetare och kontakt

Publikationer

Utvalda publikationer

Article: NATURE METABOLISM. 2026;8(3):741-756
Single-cell spatial proteomics maps human liver zonation patterns and their vulnerability to disruption in tissue architecture
Weiss CAM; Brown LA; Miranda L; Pellizzoni P; Steigerwald S; Remmert K; Hernandez JM; Borgwardt K; Kleiner DE; Ben-Moshe S; Rosenberger FA; Porat-Shliom N; Mann M
Article: NATURE. 2025;642(8067):484-491
Deep Visual Proteomics maps proteotoxicity in a genetic liver disease
Rosenberger FA; Maedler SC; Thorhauge KH; Steigerwald S; Fromme M; Lebedev M; Weiss CAM; Oeller M; Wahle M; Metousis A; Zwiebel M; Schmacke NA; Detlefsen S; Boor P; Fabian O; Frankova S; Krag A; Strnad P; Mann M
Article: NATURE METHODS. 2023;20(10):1530-1536
Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome
Rosenberger FA; Thielert M; Strauss MT; Schweizer L; Ammar C; Maedler SC; Metousis A; Skowronek P; Wahle M; Madden K; Gote-Schniering J; Semenova A; Schiller HB; Rodriguez E; Nordmann TM; Mund A; Mann M
Editorial: NATURE METHODS. 2023;20(3):320-323
Making single-cell proteomics biologically relevant
Rosenberger FA; Thielert M; Mann M

Medarbetare och kontakt

Gruppledare

Florian Andreas Rosenberger
Biträdande Lektor
Telefon +46852486619
E-postadress florian.rosenberger@ki.se

Alla medarbetare i gruppen

Kathakali De
Postdoktorala Studier
E-postadress kathakali.de@ki.se
Kilian Preussner
Forskningsassistent
E-postadress kilian.preussner@ki.se
Charu Sharma
Forskningsassistent
E-postadress charu.sharma@ki.se
Ákos Végvári
Senior Forskningsspecialist
Telefon +46852487707
E-postadress akos.vegvari@ki.se
Simon Theobald Wetzel
Doktorand
E-postadress simon.wetzel@ki.se
Jéssica Guedes
Postdoktor
E-postadress jessica.guedes@ki.se

Besöksadress

Karolinska Institutet, Medical Biochemistry and Biophysics, Solnavägen 9, Stockholm, Sweden