Rymd- och omgivningsfysiologi – Rodrigo Fernandez-Gonzalos grupp

Publikationer

Utvalda publikationer

• Article: JOURNAL OF PHYSIOLOGY-LONDON. 2025;603(14):3973-3986

  Long non-coding RNAs Kcnq1ot1 and Lncpint are involved in skeletal muscle atrophy induced by the space exposome

  Perez-Diaz S; Baselet B; Lovric A; Lundberg TR; Neefs M; Daenen L; Rullman E; Fernandez-Gonzalo R
• Journal article: RESULTS IN ENGINEERING. 2025;26:105570

  A single-step three-dimensional human skeletal muscle model for enhanced translational research

  Perez-Diaz S; Leon JG; Lopez-Ortiz S; Mandic M; Altun M; Rundqvist H; Gustafsson T; Fernandez-Gonzalo R
• Journal article: EXPERIMENTAL PHYSIOLOGY. 2025

  The search for the ultimate exercise countermeasure to preserve crew health and ensure mission success in long-duration spaceflight

  Fernandez-Gonzalo R; Schneider S; Heer M; Liphardt A-M
• Article: EMBO REPORTS. 2024;25(12):5810-5837

  The 24-hour molecular landscape after exercise in humans reveals MYC is sufficient for muscle growth

  Edman S; Jones RGIII; Jannig PR; Fernandez-Gonzalo R; Norrbom J; Thomas NT; Khadgi S; Koopmans PJ; Morena F; Chambers TL; Peterson CS; Scott LN; Greene NP; Figueiredo VC; Fry CS; Zhengye L; Lanner JT; Wen Y; Alkner B; Murach KA; von Walden F
• Journal article: GAIT & POSTURE. 2024;113:240-241

  Disproportional ventilatory response to acute incremental exercise in individuals with cerebral palsy

  Corell L; Hjalmarsson E; Fernandez-Gonzalo R; Edman S; Kizyte A; Wang R; Kruse A; Pontén E; Norrbom J; Von Walden F
• Article: DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY. 2024;66(7):902-909

  Circulating immune cell populations at rest and in response to acute endurance exercise in young adults with cerebral palsy

  Kruse A; Imery I; Corell L; Hjalmarsson E; Fernandez-Gonzalo R; Von Walden F; Reitzner SM
• Journal article: BRAIN STRUCTURE & FUNCTION. 2024;229(5):1265-1277

  Shades of gravity - effects of planetary gravity levels on electrocortical activity and neurocognitive performance

  Badali C; Wollseiffen P; Schneider S
• Article: EXPERIMENTAL PHYSIOLOGY. 2024;109(5):647-649

  Experimental bed rest as a model to investigate mechanisms of, and countermeasures against, microgravity and disease-free inactivity

  Fernandez-Gonzalo R; Deane CS; Bailey D
• Review: SPORTS MEDICINE. 2024;54(3):541-556

  Current Guidelines for the Implementation of Flywheel Resistance Training Technology in Sports: A Consensus Statement

  Beato M; de Keijzer KL; Munoz-Lopez A; Raya-Gonzalez J; Pozzo M; Alkner BA; Dello Iacono A; Vicens-Bordas J; Coratella G; Maroto-Izquierdo S; Gonzalo-Skok O; McErlain-Naylor SA; Martin-Rivera F; Hernandez-Davo JL; Arrones LS; Sabido R; de Hoyo M; Fernandez-Gonzalo R; Norrbrand L
• Article: BMC SPORTS SCIENCE MEDICINE AND REHABILITATION. 2024;16(1):45

  Relationship between maximal oxygen uptake, within-set fatigue and between-set recovery during resistance exercise in resistance-trained men and women

  Lundberg TR; Larsson G; Alstermark R; Mandic M; Fernandez-Gonzalo R
• Article: AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION. 2024;103(1):79-86

  Determinants of Frame Running Capacity in Athletes With Cerebral Palsy to Improve Training Routines and Classification Strategies

  Hjalmarsson E; Lidbeck C; Barrero Santiago L; Pingel J; Norrbom J; Sanz G; Palmcrantz A; Ponten E; von Walden F; Fernandez-Gonzalo R
• Article: NPJ MICROGRAVITY. 2023;9(1):40

  Myeloid cell infiltration in skeletal muscle after combined hindlimb unloading and radiation exposure in mice

  Emanuelsson EB; Baselet B; Neefs M; Baatout S; Proesmans B; Daenen L; Sundberg CJ; Rundqvist H; Fernandez-Gonzalo R
• Article: NPJ MICROGRAVITY. 2023;9(1):9

  Musculoskeletal research in human space flight - unmet needs for the success of crewed deep space exploration

  Liphardt A-M; Fernandez-Gonzalo R; Albracht K; Rittweger J; Vico L
• Article: FRONTIERS IN PHYSIOLOGY. 2022;13:1072040

  Extracellular vesicle characteristics and microRNA content in cerebral palsy and typically developed individuals at rest and in response to aerobic exercise

  Vechetti IJ; Norrbom J; Alkner B; Hjalmarsson E; Palmcrantz A; Ponten E; Pingel J; von Walden F; Fernandez-Gonzalo R
• Journal article: PHYSIOLOGIA. 2022;2(4):164-179

  RNA-Sequencing Muscle Plasticity to Resistance Exercise Training and Disuse in Youth and Older Age

  Fernandez-Gonzalo R; Willis CRG; Etheridge T; Deane CS
• Article: COMMUNICATIONS BIOLOGY. 2022;5(1):1121

  Single-cell sequencing deconvolutes cellular responses to exercise in human skeletal muscle

  Lovric A; Rassolie A; Alam S; Mandic M; Saini A; Altun M; Fernandez-Gonzalo R; Gustafsson T; Rullman E
• Article: DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY. 2021;63(10):1204-1212

  Reduced mitochondrial DNA and OXPHOS protein content in skeletal muscle of children with cerebral palsy

  von Walden F; Vechetti IJJ; Englund D; Figueiredo VC; Fernandez-Gonzalo R; Murach K; Pingel J; Mccarthy JJ; Stal P; Ponten E
• Article: JOURNAL OF APPLIED PHYSIOLOGY. 2021;131(3):1035-1042

  Acute endurance exercise stimulates circulating levels of mitochondrial-derived peptides in humans

  von Walden F; Fernandez-Gonzalo R; Norrbom J; Emanuelsson EB; Figueiredo VC; Gidlund E-K; Norrbrand L; Liu C; Sandstrom P; Hansson B; Wan J; Cohen P; Alkner B
• Article: FRONTIERS IN PHYSIOLOGY. 2021;12:676501

  Substantial and Reproducible Individual Variability in Skeletal Muscle Outcomes in the Cross-Over Designed Planica Bed Rest Program

  Fernandez-Gonzalo R; McDonnell AC; Simpson EJ; Macdonald IA; Rullman E; Mekjavic IB
• Article: JOURNAL OF PHYSIOLOGY-LONDON. 2021;599(13):3363-3384

  Genetic and epigenetic regulation of skeletal muscle ribosome biogenesis with exercise

  Figueiredo VC; Wen Y; Alkner B; Fernandez-Gonzalo R; Norrbom J; Vechetti IJJ; Valentino T; Mobley CB; Zentner GE; Peterson CA; McCarthy JJ; Murach KA; von Walden F
• Article: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2020;319(1):R50-R58

  Early accentuated muscle hypertrophy is strongly associated with myonuclear accretion

  Lundberg TR; Martinez-Aranda LM; Sanz G; Hansson B; von Walden F; Tesch PA; Fernandez-Gonzalo R
• Article: FRONTIERS IN PEDIATRICS. 2020;8:236

  Epigenetic Marks at the Ribosomal DNA Promoter in Skeletal Muscle Are Negatively Associated With Degree of Impairment in Cerebral Palsy

  von Walden F; Fernandez-Gonzalo R; Pingel J; McCarthy J; Stal P; Ponten E
• Article: FASEB JOURNAL. 2020;34(6):7958-7969

  Three months of bed rest induce a residual transcriptomic signature resilient to resistance exercise countermeasures

  Fernandez-Gonzalo R; Tesch PA; Lundberg TR; Alkner BA; Rullman E; Gustafsson T
• Article: CLINICAL RESEARCH IN CARDIOLOGY. 2020;109(6):655-672

  Circulatory factors associated with function and prognosis in patients with severe heart failure

  Rullman E; Melin M; Mandic M; Gonon A; Fernandez-Gonzalo R; Gustafsson T
• Article: JOURNAL OF REHABILITATION MEDICINE. 2020;52(5):jrm00060-0

  COMPARATIVE ANALYSIS OF POWER, WORK AND MUSCLE ACTIVATION DURING WEIGHT-STACK AND ISO-INERTIAL FLYWHEEL RESISTANCE EXERCISE IN YOUNG ADULTS WITH CEREBRAL PALSY

  Von Walden F; Hjalmarsson E; Reimeringer M; Kvist O; Raffalt PC; Ponten E; Fernandez-Gonzalo R
• Article: JOURNAL OF APPLIED PHYSIOLOGY. 2019;127(6):1698-1709

  Muscle2View, a CellProfiler pipeline for detection of the capillary-to-muscle fiber interface and high-content quantification of fiber type-specific histology

  Sanz G; Manuel Martinez-Aranda L; Tesch PA; Fernandez-Gonzalo R; Lundberg TR
• Article: EUROPEAN JOURNAL OF SPORT SCIENCE. 2019;19(9):1184-1194

  Comparison of the musculoskeletal effects of different iso-inertial resistance training modalities: Flywheel vs. electric-motor

  Maroto-Izquierdo S; Fernandez-Gonzalo R; Magdi HR; Manzano-Rodriguez S; Gonzalez-Gallego J; de Paz JA
• Article: APPLIED PHYSIOLOGY NUTRITION AND METABOLISM. 2019;44(8):827-833

  Regional and muscle-specific adaptations in knee extensor hypertrophy using flywheel versus conventional weight-stack resistance exercise

  Lundberg TR; Garcia-Gutierrez MT; Mandic M; Lilja M; Fernandez-Gonzalo R
• Article: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2019;317(1):R83-R92

  Skeletal muscle signaling responses to resistance exercise of the elbow extensors are not compromised by a preceding bout of aerobic exercise

  Hansson B; Olsen LA; Nicoll JX; von Walden F; Melin M; Stromberg A; Rullman E; Gustafsson T; Fry AC; Fernandez-Gonzalo R; Lundberg TR
• Review: CHROMATIN AND GENOMIC INSTABILITY IN CANCER. 2019;346:157-200

  Healthy skeletal muscle aging: The role of satellite cells, somatic mutations and exercise

  Franco I; Fernandez-Gonzalo R; Vrtacnik P; Lundberg TR; Eriksson M; Gustafsson T
• Article: AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY. 2018;315(4):R799-R809

  MEF2 as upstream regulator of the transcriptome signature in human skeletal muscle during unloading

  Rullman E; Fernandez-Gonzalo R; Mekjavic IB; Gustafsson T; Eiken O
• Article: JOURNAL OF INTERFERON AND CYTOKINE RESEARCH. 2017;37(12):531-540

  Gravity-Related Immunological Changes in Human Whole Blood Cultured Under Simulated Microgravity Using an In Vitro Cytokine Release Assay

  Van Walleghem M; Tabury K; Fernandez-Gonzalo R; Janssen A; Buchheim J-I; Chouker A; Baatout S; Moreels M
• Review: JOURNAL OF SCIENCE AND MEDICINE IN SPORT. 2017;20(10):943-951

  Skeletal muscle functional and structural adaptations after eccentric overload flywheel resistance training: a systematic review and meta-analysis

  Maroto-Izquierdo S; Garcia-Lopez D; Fernandez-Gonzalo R; Moreira OC; Gonzalez-Gallego J; de Paz JA
• Article: JOURNAL OF STRENGTH AND CONDITIONING RESEARCH. 2017;31(6):1653-1661

  EFFECTS OF INERTIAL SETTING ON POWER, FORCE, WORK, AND ECCENTRIC OVERLOAD DURING FLYWHEEL RESISTANCE EXERCISE IN WOMEN AND MEN

  Martinez-Aranda LM; Fernandez-Gonzalo R
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Finansiering

Forskningsbidrag

• Rollen av mekanotransduktion och ubiquitin-proteosomsystemet på skelettmuskelatrofi

  Karolinska Institutet

  1 January 2024 - 31 December 2027
• Sekvensering av enstaka kärnar i human skelettmuskel efter tyngdlöshet

  Gösta Fraenckels stiftelse - KI Fonder

  1 August 2023 - 31 December 2024
• Mekanismer bakom skelettmuskel- och immunsystemförändrigar vid rymdfärds

  Rymdstyrelsen

  13 April 2022 - 31 December 2024
• Transkriptomets roll i reglering av muskel- och immunsystemsförändringar vid avlastning

  Rymdstyrelsen & European Space Agency

  1 January 2021 - 31 December 2026

Medarbetare och kontakt

Gruppledare

• 

  Rodrigo Fernandez Gonzalo

  Senior Forskare | Docent

  E-postadress rodrigo.fernandez-gonzalo@ki.se

Alla medarbetare i gruppen

• 

  Constance Sophia Badali

  Anknuten till Forskning

  E-postadress constance.sophia.badali@ki.se
• 

  Rodrigo Fernandez Gonzalo

  Senior Forskare | Docent

  E-postadress rodrigo.fernandez-gonzalo@ki.se
• 

  Mirko Mandić

  Postdoktor

  E-postadress mirko.mandic@ki.se
• 

  Saul Martin Rodriguez

  Postdoktorala Studier

  E-postadress saul.martin.rodriguez@ki.se
• 

  Aikaterini Papadimitropoulou

  Doktorand

  E-postadress aikaterini.papadimitropoulou@ki.se
• 

  Sergio Pérez-Díaz

  Anknuten till Forskning

  E-postadress sergio.perez.diaz@ki.se

Andra personer med koppling till gruppen

• Zhang, Qi