Reglering av genuttryck under virusinfektion – Gerald McInerney

Publikationer

Utvalda publikationer

• Article: NATURE COMMUNICATIONS. 2024;15(1):10607

  SARS-CoV-2 N protein recruits G3BP to double membrane vesicles to promote translation of viral mRNAs

  Long S; Guzyk M; Vidakovics LP; Han X; Sun R; Wang M; Panas MD; Urgard E; Coquet JM; Merits A; Achour A; Mcinerney GM
• Article: OPEN BIOLOGY. 2023;13(5):220369

  Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH

  Schulte T; Panas MD; Han X; Williams L; Kedersha N; Fleck JS; Tan TJC; Dopico XC; Olsson A; Morro AM; Hanke L; Nilvebrant J; Giang KA; Nygren P-A; Anderson P; Achour A; McInerney GM
• Article: SCIENCE ADVANCES. 2022;8(12):eabm0220

  Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies

  Hanke L; Sheward DJ; Pankow A; Vidakovics LP; Karl V; Kim C; Urgard E; Smith NL; Astorga-Wells J; Ekstrom S; Coquet JM; McInerney GM; Murrell B
• Article: NATURE COMMUNICATIONS. 2022;13(1):155

  A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo

  Hanke L; Das H; Sheward DJ; Vidakovics LP; Urgard E; Moliner-Morro A; Kim C; Karl V; Pankow A; Smith NL; Porebski B; Fernandez-Capetillo O; Sezgin E; Pedersen GK; Coquet JM; Hallberg BM; Murrell B; McInerney GM
• Article: SCIENTIFIC REPORTS. 2021;11(1):3125

  DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in mice

  Szurgot I; Hanke L; Sheward DJ; Vidakovics LP; Murrell B; McInerney GM; Liljestrom P
• Review: ADVANCES IN VIRUS RESEARCH, VOL 111. 2021;111:111-156

  Alphavirus RNA replication in vertebrate cells.

  Ahola T; McInerney G; Merits A
• Article: NATURE COMMUNICATIONS. 2020;11(1):4420

  An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction

  Hanke L; Perez LV; Sheward DJ; Das H; Schulte T; Moliner-Morro A; Corcoran M; Achour A; Hedestam GBK; Haellberg BM; Murrell B; McInerney GM
• Article: JOURNAL OF VIROLOGY. 2020;94(7):e01681-e01619

  Sensitivity of Alphaviruses to G3BP Deletion Correlates with Efficiency of Replicase Polyprotein Processing

  Gotte B; Utt A; Fragkoudis R; Merits A; McInerney GM
• Article: JOURNAL OF GENERAL VIROLOGY. 2019;100(10):1375-1389

  RNA processing bodies are disassembled during Old World alphavirus infection

  Liu L; Weiss E; Panas MD; Gotte B; Sellberg S; Thaa B; McInerney GM
• Article: PLOS PATHOGENS. 2019;15(6):e1007842

  Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery

  Gotte B; Panas MD; Hellstrom K; Liu L; Samreen B; Larsson O; Ahola T; McInerney GM
• Article: PLOS PATHOGENS. 2018;14(1):e1006835

  Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes

  Mazzon M; Castro C; Thaa B; Liu L; Mutso M; Liu X; Mahalingam S; Griffin JL; Marsh M; McInerney GM
• Article: OPEN BIOLOGY. 2016;6(7):160078

  Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication

  Schulte T; Liu L; Panas MD; Thaa B; Dickson N; Gotte B; Achour A; McInerney GM
• Article: JOURNAL OF CELL BIOLOGY. 2016;212(7):845-860

  G3BP-Caprin 1-USP10 complexes mediate stress granule condensation and associate with 40S subunits

  Kedersha N; Panas MD; Achorn CA; Lyons S; Tisdale S; Hickman T; Thomas M; Lieberman J; McInerney GM; Ivanov P; Anderson P
• Review: METHODS. 2015;90:57-64

  Methods for the characterization of stress granules in virus infected cells

  Panas MD; Kedersha N; McInerney GM
• Article: JOURNAL OF VIROLOGY. 2015;89(22):11420-11437

  Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization

  Thaa B; Biasiotto R; Eng K; Neuvonen M; Gotte B; Rheinemann L; Mutso M; Utt A; Varghese F; Balistreri G; Merits A; Ahola T; McInerney GM
• Article: PLOS PATHOGENS. 2015;11(2):e1004659

  Viral and Cellular Proteins Containing FGDF Motifs Bind G3BP to Block Stress Granule Formation

  Panas MD; Schulte T; Thaa B; Sandalova T; Kedersha N; Achour A; McInerney GM
• Article: JOURNAL OF VIROLOGY. 2014;88(10):5888-5893

  The C-Terminal Repeat Domains of nsP3 from the Old World Alphaviruses Bind Directly to G3BP

  Panas MD; Ahola T; McInerney GM
• Article: MOLECULAR BIOLOGY OF THE CELL. 2012;23(24):4701-4712

  Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection

  Panas MD; Varjak M; Lulla A; Eng KE; Merits A; Hedestam GBK; McInerney GM
• Article: JOURNAL OF VIROLOGY. 2012;86(10):5674-5685

  Accumulation of Autophagosomes in Semliki Forest Virus-Infected Cells Is Dependent on Expression of the Viral Glycoproteins

  Eng KE; Panas MD; Murphy D; Hedestam GBK; McInerney GM
• Article: AUTOPHAGY. 2010;6(5):634-641

  A novel quantitative flow cytometry-based assay for autophagy

  Eng KE; Panas MD; Hedestam GBK; McInerney GM
• Article: JOURNAL OF VIROLOGY. 2007;81(16):8677-8684

  Semliki forest virus nonstructural protein 2 is involved in suppression of the type I interferon response

  Breakwell L; Dosenovic P; Hedestam GBK; D'Amato M; Liljestrom P; Fazakerley J; McInerney GM
• Article: MOLECULAR BIOLOGY OF THE CELL. 2005;16(8):3753-3763

  Importance of eIF2α phosphorylation assembly in alphavirus translation and stress granule regulation

  McInerney GM; Kedersha NL; Kaufman RJ; Anderson P; Liljeström P
• Visa fler

Medarbetare och kontakt

Gruppledare

• 

  Gerald Mc Inerney

  Professor

  E-postadress gerald.mcinerney@ki.se

Alla medarbetare i gruppen

• 

  Javiera Alvarez

  Anknuten till Forskning

  E-postadress javiera.alvarez@ki.se
• 

  Hanna Bley

  Postdoktor

  E-postadress hanna.bley@ki.se
• 

  Shirley Braspenning

  Postdoktorala Studier

  E-postadress shirley.braspenning@ki.se
• Wanda Franziska Christ

  Postdoktor

  E-postadress wanda.christ@ki.se
• 

  Jonathan Marie Christian Coquet

  Senior Forskare | Docent

  Telefon +46852486952

  E-postadress jonathan.coquet@ki.se
• 

  Gonzalo Fernandez Lahore

  Anknuten till Forskning

  E-postadress gonzalo.ariel.fernandez.lahore@ki.se
• 

  Mykhailo Guzyk

  Postdoktor

  E-postadress mykhailo.guzyk@ki.se
• 

  Daniel Roy Labuz

  Postdoktor

  E-postadress daniel.labuz@ki.se
• 

  Peter Liljeström

  Professor Emeritus

  Telefon +46852485990

  E-postadress peter.liljestrom@ki.se
• 

  Siwen Long

  Anknuten till Forskning

  E-postadress siwen.long@ki.se
• 

  Junjie Ma

  Anknuten till Forskning

  E-postadress junjie.ma@ki.se
• 

  Benjamin Nilsson-Payant

  Biträdande Lektor

  E-postadress benjamin.nilssonpayant@ki.se
• Albert Nylén

  Annan Grund

  E-postadress albert.nylen@ki.se
• 

  Maria Laura Anabella Perez Vidakovics

  Forskningsspecialist

  E-postadress laura.perez.vidakovics@ki.se
• 

  Marie Berit Akpiroro Peters

  Postdoktor

  E-postadress marie.peters@ki.se
• 

  Egon Urgard

  Anknuten till Forskning

  E-postadress egon.urgard@ki.se
• Léna Vandenabeele

  Doktorand

  E-postadress lena.vandenabeele@ki.se
• 

  Juliana de Oliveira Faria

  Doktorand

  E-postadress juliana.faria@ki.se