Reglering av genuttryck under virusinfektion – Gerald McInerney

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Article: NATURE COMMUNICATIONS. 2024;15(1):10607
SARS-CoV-2 N protein recruits G3BP to double membrane vesicles to promote translation of viral mRNAs
Long S; Guzyk M; Vidakovics LP; Han X; Sun R; Wang M; Panas MD; Urgard E; Coquet JM; Merits A; Achour A; Mcinerney GM
Article: OPEN BIOLOGY. 2023;13(5):220369
Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH
Schulte T; Panas MD; Han X; Williams L; Kedersha N; Fleck JS; Tan TJC; Dopico XC; Olsson A; Morro AM; Hanke L; Nilvebrant J; Giang KA; Nygren P-A; Anderson P; Achour A; McInerney GM
Article: SCIENCE ADVANCES. 2022;8(12):eabm0220
Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies
Hanke L; Sheward DJ; Pankow A; Vidakovics LP; Karl V; Kim C; Urgard E; Smith NL; Astorga-Wells J; Ekstrom S; Coquet JM; McInerney GM; Murrell B
Article: NATURE COMMUNICATIONS. 2022;13(1):155
A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo
Hanke L; Das H; Sheward DJ; Vidakovics LP; Urgard E; Moliner-Morro A; Kim C; Karl V; Pankow A; Smith NL; Porebski B; Fernandez-Capetillo O; Sezgin E; Pedersen GK; Coquet JM; Hallberg BM; Murrell B; McInerney GM
Article: SCIENTIFIC REPORTS. 2021;11(1):3125
DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in mice
Szurgot I; Hanke L; Sheward DJ; Vidakovics LP; Murrell B; McInerney GM; Liljestrom P
Review: ADVANCES IN VIRUS RESEARCH, VOL 111. 2021;111:111-156
Alphavirus RNA replication in vertebrate cells.
Ahola T; McInerney G; Merits A
Article: NATURE COMMUNICATIONS. 2020;11(1):4420
An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction
Hanke L; Perez LV; Sheward DJ; Das H; Schulte T; Moliner-Morro A; Corcoran M; Achour A; Hedestam GBK; Haellberg BM; Murrell B; McInerney GM
Article: JOURNAL OF VIROLOGY. 2020;94(7):e01681-e01619
Sensitivity of Alphaviruses to G3BP Deletion Correlates with Efficiency of Replicase Polyprotein Processing.
Götte B; Utt A; Fragkoudis R; Merits A; McInerney GM
Article: JOURNAL OF GENERAL VIROLOGY. 2019;100(10):1375-1389
RNA processing bodies are disassembled during Old World alphavirus infection
Liu L; Weiss E; Panas MD; Gotte B; Sellberg S; Thaa B; McInerney GM
Article: PLOS PATHOGENS. 2019;15(6):e1007842
Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery
Gotte B; Panas MD; Hellstrom K; Liu L; Samreen B; Larsson O; Ahola T; McInerney GM
Article: PLOS PATHOGENS. 2018;14(1):e1006835
Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes
Mazzon M; Castro C; Thaa B; Liu L; Mutso M; Liu X; Mahalingam S; Griffin JL; Marsh M; McInerney GM
Article: OPEN BIOLOGY. 2016;6(7):160078
Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication
Schulte T; Liu L; Panas MD; Thaa B; Dickson N; Gotte B; Achour A; McInerney GM
Article: JOURNAL OF CELL BIOLOGY. 2016;212(7):845-860
G3BP-Caprin 1-USP10 complexes mediate stress granule condensation and associate with 40S subunits
Kedersha N; Panas MD; Achorn CA; Lyons S; Tisdale S; Hickman T; Thomas M; Lieberman J; McInerney GM; Ivanov P; Anderson P
Review: METHODS. 2015;90:57-64
Methods for the characterization of stress granules in virus infected cells
Panas MD; Kedersha N; McInerney GM
Article: JOURNAL OF VIROLOGY. 2015;89(22):11420-11437
Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization
Thaa B; Biasiotto R; Eng K; Neuvonen M; Gotte B; Rheinemann L; Mutso M; Utt A; Varghese F; Balistreri G; Merits A; Ahola T; McInerney GM
Article: PLOS PATHOGENS. 2015;11(2):e1004659
Viral and Cellular Proteins Containing FGDF Motifs Bind G3BP to Block Stress Granule Formation
Panas MD; Schulte T; Thaa B; Sandalova T; Kedersha N; Achour A; McInerney GM
Article: JOURNAL OF VIROLOGY. 2014;88(10):5888-5893
The C-Terminal Repeat Domains of nsP3 from the Old World Alphaviruses Bind Directly to G3BP
Panas MD; Ahola T; McInerney GM
Article: MOLECULAR BIOLOGY OF THE CELL. 2012;23(24):4701-4712
Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection
Panas MD; Varjak M; Lulla A; Eng KE; Merits A; Hedestam GBK; McInerney GM
Article: JOURNAL OF VIROLOGY. 2012;86(10):5674-5685
Accumulation of Autophagosomes in Semliki Forest Virus-Infected Cells Is Dependent on Expression of the Viral Glycoproteins
Eng KE; Panas MD; Murphy D; Hedestam GBK; McInerney GM
Article: AUTOPHAGY. 2010;6(5):634-641
A novel quantitative flow cytometry-based assay for autophagy
Eng KE; Panas MD; Hedestam GBK; McInerney GM
Article: JOURNAL OF VIROLOGY. 2007;81(16):8677-8684
Semliki forest virus nonstructural protein 2 is involved in suppression of the type I interferon response
Breakwell L; Dosenovic P; Hedestam GBK; D'Amato M; Liljestrom P; Fazakerley J; McInerney GM
Article: MOLECULAR BIOLOGY OF THE CELL. 2005;16(8):3753-3763
Importance of eIF2α phosphorylation assembly in alphavirus translation and stress granule regulation
McInerney GM; Kedersha NL; Kaufman RJ; Anderson P; Liljeström P
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Reglering av genuttryck under virusinfektion – Gerald McInerney

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