Neuroinfektioner and neuroinflammation – Federico Iovinos grupp

Vi undersöker molekylära mekanismer för neuronal skada och hjärnans immunsvar under bakteriell meningit och utnyttjar den grundläggande kunskapen för att utveckla nya terapeutiska metoder för att skydda neuroner från bakteriell interaktion.

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Institutionen för neurovetenskap

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Publikationer
Medarbetare och kontakt

Publikationer

Utvalda publikationer

Article: NEUROBIOLOGY OF DISEASE. 2024;195:106484
Spatio-temporal brain invasion pattern of Streptococcus pneumoniae and dynamic changes in the cellular environment in bacteremia-derived meningitis.
Farmen K; Tofiño-Vian M; Wellfelt K; Olsson L; Iovino F
Article: ISCIENCE. 2024;27(4):109583
The single D380 amino acid substitution increases pneumolysin cytotoxicity towards neuronal cells
Serra S; Iannotti V; Ferrante M; Tofiño-Vian M; Baxendale J; Silberberg G; Kohler TP; Hammerschmidt S; Ulijasz AT; Iovino F
Article: JAMA NETWORK OPEN. 2024;7(1):e2352402
Increased Risk of Long-Term Disabilities Following Childhood Bacterial Meningitis in Sweden.
Mohanty S; Johansson Kostenniemi U; Silfverdal SA; Salomonsson S; Iovino F; Sarpong EM; Bencina G; Bruze G
Review: FRONTIERS IN NEUROLOGY. 2023;14:822575
Bacterial meningitis in Africa.
Barichello T; Rocha Catalão CH; Rohlwink UK; van der Kuip M; Zaharie D; Solomons RS; van Toorn R; Tutu van Furth M; Hasbun R; Iovino F; Namale VS
Article: MBIO. 2022;13(5):e0188622-e01822
Dysfunctional Glymphatic System with Disrupted Aquaporin 4 Expression Pattern on Astrocytes Causes Bacterial Product Accumulation in the CSF during Pneumococcal Meningitis
Generoso JS; Thorsdottir S; Collodel A; Dominguini D; Santo RRE; Petronilho F; Barichello T; Iovino F
Article: PLOS PATHOGENS. 2021;17(3):e1009432
Neuronal death in pneumococcal meningitis is triggered by pneumolysin and RrgA interactions with β-actin
Tabusi M; Thorsdottir S; Lysandrou M; Narciso AR; Minoia M; Srambickal CV; Widengren J; Henriques-Normark B; Iovino F
Editorial comment: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2021;11:790761
Editorial: Host-Pathogen Interaction in the Central Nervous System
Barichello T; Iovino F
Review: FRONTIERS IN CELLULAR NEUROSCIENCE. 2021;15:680858
Neuronal Damage and Neuroinflammation, a Bridge Between Bacterial Meningitis and Neurodegenerative Diseases
Farmen K; Tofino-Vian M; Iovino F
Review: FRONTIERS IN MICROBIOLOGY. 2019;10:576
The Role of Microglia in Bacterial Meningitis: Inflammatory Response, Experimental Models and New Neuroprotective Therapeutic Strategies
Thorsdottir S; Henriques-Normark B; Iovino F

Medarbetare och kontakt

Gruppledare

Federico Iovino
Senior Forskare | Docent
Telefon +46852487121
E-postadress federico.iovino@ki.se

Alla medarbetare i gruppen

Kristine Farmen
Doktorand
E-postadress kristine.farmen@ki.se
Federico Iovino
Senior Forskare | Docent
Telefon +46852487121
E-postadress federico.iovino@ki.se
Simona Serra
Doktorand
E-postadress simona.serra@ki.se
Niels Vander Elst
Postdoktorala Studier
E-postadress niels.vander.elst@ki.se

Besöksadress

Karolinska Institutet, Neuroscience, Solnavägen 9, Stockholm, 17165, Sweden

Lotte Merlijn

E-post: lotte.merlijn@stud.ki.se

Georgia Yfanti

E-post: georgia.yfanti@stud.ki.se

Kontakta oss

Kontaktinformation för Federico Iovinos grupp vid institutionen för neurovetenskap.

Post

Karolinska Institutet
Department of Neuroscience
171 77 Stockholm

Leveranser (varor, större paket, etc.)

Tomtebodavägen 16
171 65 Solna