Genetisk modifiering av NK-celler för optimerade funktioner mot cancer – Arnika Wagner forskarteam

Publikationer

Utvalda publikationer

• Article: CYTOTHERAPY. 2023;25(7):763-772

  Challenges in αCD38-chimeric antigen receptor (CAR)-expressing natural killer (NK) cell-based immunotherapy in multiple myeloma: Harnessing the CD38dim phenotype of cytokine-stimulated NK cells as a strategy to prevent fratricide

  Karvouni M; Vidal-Manrique M; Susek KH; Hussain A; Gilljam M; Zhang Y; Gray JD; Lund J; Kaufmann G; Ljunggren H-G; Ji H; Lundqvist A; Wagner AK; Guo W; Alici E
• Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2023;72(5):1153-1167

  Generation of NK cells with chimeric-switch receptors to overcome PD1-mediated inhibition in cancer immunotherapy

  Susek KH; Schwietzer YA; Karvouni M; Gilljam M; Keszei M; Hussain A; Lund J; Kashif M; Lundqvist A; Ljunggren H-G; Nahi H; Wagner AK; Alici E
• Article: BIOMOLECULAR INTERACTIONS, PT A. 2023;178:43-61

  A tractable microscopy- and flow cytometry-based method to measure natural killer cell-mediated killing and infiltration of tumor spheroids.

  Schwietzer YA; Susek KH; Chen Z; Alici E; Wagner AK
• Article: ISCIENCE. 2022;25(10):105137

  PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype

  Wagner AK; Kadri N; Tibbitt C; van de Ven K; Bagawath-Singh S; Oliinyk D; LeGresley E; Campbell N; Trittel S; Riese P; Ribacke U; Sandalova T; Achour A; Karre K; Chambers BJ
• Article: CELL REPORTS MEDICINE. 2022;3(2):100508

  Autologous NK cells as consolidation therapy following stem cell transplantation in multiple myeloma

  Nahi H; Chrobok M; Meinke S; Gran C; Marquardt N; Afram G; Sutlu T; Gilljam M; Stellan B; Wagner AK; Blomberg P; Holmqvist P-H; Walther-Jallow L; Mellstrom K; Liwing J; Gustafsson C; Mansson R; Klimkowska M; Gahrton G; Lund J; Ljungman P; Ljunggren H-G; Alici E
• Article: FRONTIERS IN IMMUNOLOGY. 2022;13:896242

  Process Development for Adoptive Cell Therapy in Academia: A Pipeline for Clinical-Scale Manufacturing of Multiple TCR-T Cell Products

  Silva DN; Chrobok M; Rovesti G; Healy K; Wagner AK; Maravelia P; Gatto F; Mazza M; Mazzotti L; Lohmann V; Chen MS; Sallberg M; Buggert M; Pasetto A
• Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2020;50(4):494-504

  IL-15 and CD155 expression regulate LAT expression in murine DNAM1⁺ NK cells, enhancing their effectors functions

  Luu TT; Wagner AK; Schmied L; Meinke S; Freund JE; Kambayashi T; Ravens I; Achour A; Bernhardt G; Chambers BJ; Hoglund P; Kadri N
• Article: PLOS ONE. 2019;14(2):e0211927

  Infectious complications and NK cell depletion following daratumumab treatment of Multiple Myeloma

  Nahi H; Chrobok M; Gran C; Lund J; Gruber A; Gahrton G; Ljungman P; Wagner AK; Alici E
• Article: NATURE COMMUNICATIONS. 2017;8:15627

  Expression of CD226 is associated to but not required for NK cell education

  Wagner AK; Kadri N; Snall J; Brodin P; Gilfillan S; Colonna M; Bernhardt GN; Hoglund P; Karre K; Chambers BJ
• Article: CANCER IMMUNOLOGY RESEARCH. 2016;4(2):113-123

  Retuning of Mouse NK Cells after Interference with MHC Class I Sensing Adjusts Self-Tolerance but Preserves Anticancer Response

  Wagner AK; Wickstrom SL; Tallerico R; Salam S; Lakshmikanth T; Brauner H; Hoglund P; Carbone E; Johansson MH; Karre K

Medarbetare och kontakt

Gruppledare

• 

  Arnika Kathleen Wagner

  Senior Forskare

  E-postadress arnika.wagner@ki.se

Alla medarbetare i gruppen

• 

  Anna Pumpe

  Doktorand

  E-postadress anna.pumpe@ki.se
• 

  Arnika Kathleen Wagner

  Senior Forskare

  E-postadress arnika.wagner@ki.se

Anders Norman

Forskningsingenjör

E-post: anders.norman@ki.se

Nutsa Burduli

Assistent Klinisk

E-post: nutsa.burduli@ki.se