Molekylär och cellulär neuroendokrinologi – Tibor Harkanys grupp

Article: NATURE. 2024;628(8009):826-834

A brainstem-hypothalamus neuronal circuit reduces feeding upon heat exposure.

Benevento M; Alpár A; Gundacker A; Afjehi L; Balueva K; Hevesi Z; Hanics J; Rehman S; Pollak DD; Lubec G; Wulff P; Prevot V; Horvath TL; Harkany T

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2024;121(16):e2309211121

A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues.

Szodorai E; Hevesi Z; Wagner L; Hökfelt TGM; Harkany T; Schnell R

Article: MOLECULAR PSYCHIATRY. 2024;29(4):859-873

Gestational immune activation disrupts hypothalamic neurocircuits of maternal care behavior.

Zambon A; Rico LC; Herman M; Gundacker A; Telalovic A; Hartenberger L-M; Kuehn R; Romanov RA; Hussaini SA; Harkany T; Pollak DD

Article: NATURE COMMUNICATIONS. 2024;15(1):2762

Transient expression of the neuropeptide galanin modulates peripheral‑to‑central connectivity in the somatosensory thalamus during whisker development in mice.

Hevesi Z; Bakker J; Tretiakov EO; Adori C; Raabgrund A; Barde SS; Caramia M; Krausgruber T; Ladstätter S; Bock C; Hökfelt T; Harkany T

Editorial comment: SCIENCE. 2023;382(6672):764-765

Grabbing neuropeptide signals in the brain.

Romanov RA; Harkany T

Editorial comment: ACTA PHYSIOLOGICA. 2023;239(2):e14033

Neuroglia: Function and Pathology by Alexei Verkhratsky and Arthur M. Butt.

Harkany T; Hökfelt T

Review: JOURNAL OF NEUROENDOCRINOLOGY. 2023;35(9):e13320

Adverse effects of gestational ω-3 and ω-6 polyunsaturated fatty acid imbalance on the programming of fetal brain development.

Cinquina V; Keimpema E; Pollak DD; Harkany T

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(31):e2222095120

Neuronal diversity of neuropeptide signaling, including galanin, in the mouse locus coeruleus.

Caramia M; Romanov RA; Sideromenos S; Hevesi Z; Zhao M; Krasniakova M; Xu Z-QD; Harkany T; Hökfelt TGM

Article: ACTA PHYSIOLOGICA. 2023;238(3):e13973

Brain-wide mapping of efferent projections of glutamatergic (Onecut3+ ) neurons in the lateral mouse hypothalamus.

Zupančič M; Tretiakov E; Máté Z; Erdélyi F; Szabó G; Clotman F; Hökfelt T; Harkany T; Keimpema E

Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):3565

Author Correction: A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology.

Petersen J; Englmaier L; Artemov AV; Poverennaya I; Mahmoud R; Bouderlique T; Tesarova M; Deviatiiarov R; Szilvásy-Szabó A; Akkuratov EE; Pajuelo Reguera D; Zeberg H; Kaucka M; Kastriti ME; Krivanek J; Radaszkiewicz T; Gömöryová K; Knauth S; Potesil D; Zdrahal Z; Ganji RS; Grabowski A; Buhl ME; Zikmund T; Kavkova M; Axelson H; Lindgren D; Kramann R; Kuppe C; Erdélyi F; Máté Z; Szabó G; Koehne T; Harkany T; Fried K; Kaiser J; Boor P; Fekete C; Rozman J; Kasparek P; Prochazka J; Sedlacek R; Bryja V; Gusev O; Adameyko I

Article: NATURE COMMUNICATIONS. 2023;14(1):3092

A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology.

Petersen J; Englmaier L; Artemov AV; Poverennaya I; Mahmoud R; Bouderlique T; Tesarova M; Deviatiiarov R; Szilvásy-Szabó A; Akkuratov EE; Pajuelo Reguera D; Zeberg H; Kaucka M; Kastriti ME; Krivanek J; Radaszkiewicz T; Gömöryová K; Knauth S; Potesil D; Zdrahal Z; Ganji RS; Grabowski A; Buhl ME; Zikmund T; Kavkova M; Axelson H; Lindgren D; Kramann R; Kuppe C; Erdélyi F; Máté Z; Szabó G; Koehne T; Harkany T; Fried K; Kaiser J; Boor P; Fekete C; Rozman J; Kasparek P; Prochazka J; Sedlacek R; Bryja V; Gusev O; Adameyko I

Preprint: BIORXIV. 2023;BIORXIV

Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons.

Cronin SJF; Yu W; Hale A; Licht-Mayer S; Crabtree MJ; Korecka JA; Tretiakov EO; Sealey-Cardona M; Somlyay M; Onji M; An M; Fox JD; Turnes BL; Gomez-Diaz C; da Luz Scheffer D; Cikes D; Nagy V; Weidinger A; Wolf A; Reither H; Chabloz A; Kavirayani A; Rao S; Andrews N; Latremoliere A; Costigan M; Douglas G; Freitas FC; Pifl C; Walz R; Konrat R; Mahad DJ; Koslov AV; Latini A; Isacson O; Harkany T; Hallett PJ; Bagby S; Woolf CJ; Channon KM; Je HS; Penninger JM

Article: NEUROCHEMICAL RESEARCH. 2023;48(4):1242-1253

Resident Astrocytes can Limit Injury to Developing Hippocampal Neurons upon THC Exposure.

Krassnitzer M; Boisvert B; Beiersdorf J; Harkany T; Keimpema E

Article: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. 2023;49(1):e12887

Regional redistribution of CB1 cannabinoid receptors in human foetal brains with Down's syndrome and their functional modifications in Ts65Dn+/+ mice.

Patthy Á; Hanics J; Zachar G; Kovács GG; Harkany T; Alpár A

Article: EMBO JOURNAL. 2022;41(24):e111648

An accessory prefrontal cortex-thalamus circuit sculpts maternal behavior in virgin female mice.

Glat M; Gundacker A; Cuenca Rico L; Czuczu B; Ben-Simon Y; Harkany T; Pollak DD

Article: NATURE COMMUNICATIONS. 2022;13(1):5944

A hypothalamic dopamine locus for psychostimulant-induced hyperlocomotion in mice.

Korchynska S; Rebernik P; Pende M; Boi L; Alpár A; Tasan R; Becker K; Balueva K; Saghafi S; Wulff P; Horvath TL; Fisone G; Dodt H-U; Hökfelt T; Harkany T; Romanov RA

Review: NATURE REVIEWS NEUROSCIENCE. 2022;23(10):611-627

Ontogenetic rules for the molecular diversification of hypothalamic neurons.

Benevento M; Hökfelt T; Harkany T

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(16):e2200476119

A hypothalamic pathway for Augmentor α-controlled body weight regulation.

Ahmed M; Kaur N; Cheng Q; Shanabrough M; Tretiakov EO; Harkany T; Horvath TL; Schlessinger J

Article: VACCINES. 2022;10(4):516

Preclinical Establishment of a Divalent Vaccine against SARS-CoV-2.

Hevesi Z; Gerges DA; Kapps S; Freire R; Schmidt S; Pollak DD; Schmetterer K; Frey T; Lang R; Winnicki W; Schmidt A; Harkany T; Wagner L

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(7):e2108768119

Disrupted Cacna1c gene expression perturbs spontaneous Ca2+ activity causing abnormal brain development and increased anxiety.

Smedler E; Louhivuori L; Romanov RA; Masini D; Dehnisch Ellström I; Wang C; Caramia M; West Z; Zhang S; Rebellato P; Malmersjö S; Brusini I; Kanatani S; Fisone G; Harkany T; Uhlén P

Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2022;55(3):725-732

3D-printed design of a stereotaxic adaptor for the precision targeting of brain structures in infant mice.

Steffens S; Bakker J; Glat M; Keimpema E; Pollak DD; Hökfelt T; Harkany T

Editorial comment: SCIENCE. 2021;374(6574):1449-1450

Biological basis of cannabinoid medicines.

Keimpema E; Di Marzo V; Harkany T

Article: CELL REPORTS. 2021;37(2):109800

Functional heterogeneity of POMC neurons relies on mTORC1 signaling.

Saucisse N; Mazier W; Simon V; Binder E; Catania C; Bellocchio L; Romanov RA; Léon S; Matias I; Zizzari P; Quarta C; Cannich A; Meece K; Gonzales D; Clark S; Becker JM; Yeo GSH; Fioramonti X; Merkle FT; Wardlaw SL; Harkany T; Massa F; Marsicano G; Cota D

Article: CANNABIS AND CANNABINOID RESEARCH. 2021;6(5):381-388

Physiological Rules of Endocannabinoid Action During Fetal and Neonatal Brain Development.

Harkany T; Cinquina V

Review: JOURNAL OF CLINICAL MEDICINE. 2021;10(8):1555

Neuropathology of the Brainstem to Mechanistically Understand and to Treat Alzheimer's Disease.

Patthy Á; Murai J; Hanics J; Pintér A; Zahola P; Hökfelt TGM; Harkany T; Alpár A

Article: CANNABIS AND CANNABINOID RESEARCH. 2021;6(2):119-136

Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB1 Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in Drosophila melanogaster.

Tortoriello G; Beiersdorf J; Romani S; Williams G; Cameron GA; Mackie K; Williams MJ; Di Marzo V; Keimpema E; Doherty P; Harkany T

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(7):e1921123118

Secretagogin marks amygdaloid PKCδ interneurons and modulates NMDA receptor availability.

Hevesi Z; Zelena D; Romanov RA; Hanics J; Ignácz A; Zambon A; Pollak DD; Lendvai D; Schlett K; Palkovits M; Harkany T; Hökfelt TGM; Alpár A

Article: JCI INSIGHT. 2020;5(23):135418

Adverse effects of Δ9-tetrahydrocannabinol on neuronal bioenergetics during postnatal development.

Beiersdorf J; Hevesi Z; Calvigioni D; Pyszkowski J; Romanov R; Szodorai E; Lubec G; Shirran S; Botting CH; Kasper S; Guy GW; Gray R; Di Marzo V; Harkany T; Keimpema E

Article: MOLECULAR CANCER RESEARCH. 2020;18(10):1522-1533

HCN Channel Activity Balances Quiescence and Proliferation in Neural Stem Cells and Is a Selective Target for Neuroprotection During Cancer Treatment.

Johard H; Omelyanenko A; Fei G; Zilberter M; Dave Z; Abu-Youssef R; Schmidt L; Harisankar A; Vincent CT; Walfridsson J; Nelander S; Harkany T; Blomgren K; Andäng M

Article: NATURE COMMUNICATIONS. 2020;11(1):4816

Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth.

Krivanek J; Soldatov RA; Kastriti ME; Chontorotzea T; Herdina AN; Petersen J; Szarowska B; Landova M; Matejova VK; Holla LI; Kuchler U; Zdrilic IV; Vijaykumar A; Balic A; Marangoni P; Klein OD; Neves VCM; Yianni V; Sharpe PT; Harkany T; Metscher BD; Bajénoff M; Mina M; Fried K; Kharchenko PV; Adameyko I

Editorial comment: SIGNAL TRANSDUCTION AND TARGETED THERAPY. 2020;5(1):189

The p(l)ot thickens: cannabinoid receptors on astroglial mitochondria coordinate animal behaviors by regulating lactate availability for neurons.

Keimpema E; Harkany T; Alpár A

Article: CELL. 2020;182(4):960-975.e15

A Neuro-hormonal Circuit for Paternal Behavior Controlled by a Hypothalamic Network Oscillation.

Stagkourakis S; Smiley KO; Williams P; Kakadellis S; Ziegler K; Bakker J; Brown RSE; Harkany T; Grattan DR; Broberger C

Article: NATURE. 2020;582(7811):246-252

Molecular design of hypothalamus development.

Romanov RA; Tretiakov EO; Kastriti ME; Zupancic M; Häring M; Korchynska S; Popadin K; Benevento M; Rebernik P; Lallemend F; Nishimori K; Clotman F; Andrews WD; Parnavelas JG; Farlik M; Bock C; Adameyko I; Hökfelt T; Keimpema E; Harkany T

Article: CELL. 2020;181(6):1246-1262.e22

Identification of ALK in Thinness.

Orthofer M; Valsesia A; Mägi R; Wang Q-P; Kaczanowska J; Kozieradzki I; Leopoldi A; Cikes D; Zopf LM; Tretiakov EO; Demetz E; Hilbe R; Boehm A; Ticevic M; Nõukas M; Jais A; Spirk K; Clark T; Amann S; Lepamets M; Neumayr C; Arnold C; Dou Z; Kuhn V; Novatchkova M; Cronin SJF; Tietge UJF; Müller S; Pospisilik JA; Nagy V; Hui C-C; Lazovic J; Esterbauer H; Hagelkruys A; Tancevski I; Kiefer FW; Harkany T; Haubensak W; Neely GG; Metspalu A; Hager J; Gheldof N; Penninger JM

Article: EMBO JOURNAL. 2020;39(1):e100882

Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants.

Korchynska S; Krassnitzer M; Malenczyk K; Prasad RB; Tretiakov EO; Rehman S; Cinquina V; Gernedl V; Farlik M; Petersen J; Hannes S; Schachenhofer J; Reisinger SN; Zambon A; Asplund O; Artner I; Keimpema E; Lubec G; Mulder J; Bock C; Pollak DD; Romanov RA; Pifl C; Groop L; Hökfelt TG; Harkany T

Article: MOLECULAR PSYCHIATRY. 2020;25(1):22-36

Life-long epigenetic programming of cortical architecture by maternal 'Western' diet during pregnancy.

Cinquina V; Calvigioni D; Farlik M; Halbritter F; Fife-Gernedl V; Shirran SL; Fuszard MA; Botting CH; Poullet P; Piscitelli F; Máté Z; Szabó G; Yanagawa Y; Kasper S; Di Marzo V; Mackie K; McBain CJ; Bock C; Keimpema E; Harkany T

Article: CEREBRAL CORTEX. 2019;29(12):5166-5179

The Glutamine Transporter Slc38a1 Regulates GABAergic Neurotransmission and Synaptic Plasticity.

Qureshi T; Sørensen C; Berghuis P; Jensen V; Dobszay MB; Farkas T; Dalen KT; Guo C; Hassel B; Utheim TP; Hvalby Ø; Hafting T; Harkany T; Fyhn M; Chaudhry FA

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(51):25958-25967

Brain-wide genetic mapping identifies the indusium griseum as a prenatal target of pharmacologically unrelated psychostimulants.

Fuzik J; Rehman S; Girach F; Miklosi AG; Korchynska S; Arque G; Romanov RA; Hanics J; Wagner L; Meletis K; Yanagawa Y; Kovacs GG; Alpár A; Hökfelt TGM; Harkany T

Review: ANNUAL REVIEW OF NEUROSCIENCE. 2019;42:1-26

Unified Classification of Molecular, Network, and Endocrine Features of Hypothalamic Neurons.

Romanov RA; Alpár A; Hökfelt T; Harkany T

Article: BRAIN STRUCTURE & FUNCTION. 2019;224(6):2061-2078

Secretagogin expression in the vertebrate brainstem with focus on the noradrenergic system and implications for Alzheimer's disease.

Zahola P; Hanics J; Pintér A; Máté Z; Gáspárdy A; Hevesi Z; Echevarria D; Adori C; Barde S; Törőcsik B; Erdélyi F; Szabó G; Wagner L; Kovacs GG; Hökfelt T; Harkany T; Alpár A

Article: CURRENT OPINION IN NEUROBIOLOGY. 2019;56:16-23

Hypothalamic cell diversity: non-neuronal codes for long-distance volume transmission by neuropeptides.

Alpár A; Benevento M; Romanov RA; Hökfelt T; Harkany T

Article: JCI INSIGHT. 2019;4(4):122947

GPR55 controls functional differentiation of self-renewing epithelial progenitors for salivation.

Korchynska S; Lutz MI; Borók E; Pammer J; Cinquina V; Fedirko N; Irving AJ; Mackie K; Harkany T; Keimpema E

Published conference paper: JOURNAL OF INTERNAL MEDICINE. 2018;284(6):568-580

Novel insights into the spatial and temporal complexity of hypothalamic organization through precision methods allowing nanoscale resolution.

Alpár A; Harkany T

Article: EMBO JOURNAL. 2018;37(21):e100087

Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress.

Alpár A; Zahola P; Hanics J; Hevesi Z; Korchynska S; Benevento M; Pifl C; Zachar G; Perugini J; Severi I; Leitgeb P; Bakker J; Miklosi AG; Tretiakov E; Keimpema E; Arque G; Tasan RO; Sperk G; Malenczyk K; Máté Z; Erdélyi F; Szabó G; Lubec G; Palkovits M; Giordano A; Hökfelt TG; Romanov RA; Horvath TL; Harkany T

Article: CELL. 2018;175(4):1031-1044.e18

Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting.

Cohen M; Giladi A; Gorki A-D; Solodkin DG; Zada M; Hladik A; Miklosi A; Salame T-M; Halpern KB; David E; Itzkovitz S; Harkany T; Knapp S; Amit I

Review: CELLULAR SIGNALLING. 2018;50:142-159

Diversity matters: combinatorial information coding by GABAA receptor subunits during spatial learning and its allosteric modulation.

Szodorai E; Bampali K; Romanov RA; Kasper S; Hökfelt T; Ernst M; Lubec G; Harkany T

Article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(9):3757-3768

Ca2+-binding protein NECAB2 facilitates inflammatory pain hypersensitivity.

Zhang M-D; Su J; Adori C; Cinquina V; Malenczyk K; Girach F; Peng C; Ernfors P; Löw P; Borgius L; Kiehn O; Watanabe M; Uhlén M; Mitsios N; Mulder J; Harkany T; Hökfelt T

Article: MOLECULAR METABOLISM. 2018;14:108-120

Secretagogin protects Pdx1 from proteasomal degradation to control a transcriptional program required for β cell specification.

Malenczyk K; Szodorai E; Schnell R; Lubec G; Szabó G; Hökfelt T; Harkany T

Article: PROTEOMICS. 2018;18(14):e1800139

Resolution Matters: Correlating Quantitative Proteomics and Nanoscale-Precision Microscopy for Reconstructing Synapse Identity.

Miklosi AG; Del Favero G; Marko D; Harkany T; Lubec G

Article: SCIENCE SIGNALING. 2018;11(529):eaao1815

Chemical synapses without synaptic vesicles: Purinergic neurotransmission through a CALHM1 channel-mitochondrial signaling complex.

Romanov RA; Lasher RS; High B; Savidge LE; Lawson A; Rogachevskaja OA; Zhao H; Rogachevsky VV; Bystrova MF; Churbanov GD; Adameyko I; Harkany T; Yang R; Kidd GJ; Marambaud P; Kinnamon JC; Kolesnikov SS; Finger TE

Article: BRAIN STRUCTURE & FUNCTION. 2018;223(3):1501-1518

GABAA receptor subunit deregulation in the hippocampus of human foetuses with Down syndrome.

Milenkovic I; Stojanovic T; Aronica E; Fülöp L; Bozsó Z; Máté Z; Yanagawa Y; Adle-Biassette H; Lubec G; Szabó G; Harkany T; Kovács GG; Keimpema E

Article: JOURNAL OF NEUROSCIENCE. 2017;37(34):8166-8179

Selective Silencing of Hippocampal Parvalbumin Interneurons Induces Development of Recurrent Spontaneous Limbic Seizures in Mice.

Drexel M; Romanov RA; Wood J; Weger S; Heilbronn R; Wulff P; Tasan RO; Harkany T; Sperk G

Article: EMBO JOURNAL. 2017;36(14):2107-2125

A TRPV1-to-secretagogin regulatory axis controls pancreatic β-cell survival by modulating protein turnover.

Malenczyk K; Girach F; Szodorai E; Storm P; Segerstolpe Å; Tortoriello G; Schnell R; Mulder J; Romanov RA; Borók E; Piscitelli F; Di Marzo V; Szabó G; Sandberg R; Kubicek S; Lubec G; Hökfelt T; Wagner L; Groop L; Harkany T

Article: SCIENCE. 2017;356(6343):1168-1171

miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes.

Peng C; Li L; Zhang M-D; Bengtsson Gonzales C; Parisien M; Belfer I; Usoskin D; Abdo H; Furlan A; Häring M; Lallemend F; Harkany T; Diatchenko L; Hökfelt T; Hjerling-Leffler J; Ernfors P

Article: NATURE BIOTECHNOLOGY. 2017;35(5):444-452

Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model.

Rivetti di Val Cervo P; Romanov RA; Spigolon G; Masini D; Martín-Montañez E; Toledo EM; La Manno G; Feyder M; Pifl C; Ng Y-H; Sánchez SP; Linnarsson S; Wernig M; Harkany T; Fisone G; Arenas E

Article: CEREBRAL CORTEX. 2017;27(4):2453-2468

Functional Differentiation of Cholecystokinin-Containing Interneurons Destined for the Cerebral Cortex.

Calvigioni D; Máté Z; Fuzik J; Girach F; Zhang M-D; Varro A; Beiersdorf J; Schwindling C; Yanagawa Y; Dockray GJ; McBain CJ; Hökfelt T; Szabó G; Keimpema E; Harkany T

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(10):E2006-E2015

Secretagogin-dependent matrix metalloprotease-2 release from neurons regulates neuroblast migration.

Hanics J; Szodorai E; Tortoriello G; Malenczyk K; Keimpema E; Lubec G; Hevesi Z; Lutz MI; Kozsurek M; Puskár Z; Tóth ZE; Wagner L; Kovács GG; Hökfelt TGM; Harkany T; Alpár A

Review: JOURNAL OF ENDOCRINOLOGY. 2017;232(3):R161-R172

Molecular diversity of corticotropin-releasing hormone mRNA-containing neurons in the hypothalamus.

Romanov RA; Alpár A; Hökfelt T; Harkany T

Article: ONCOGENE. 2017;36(6):777-786

Endogenous GABAA receptor activity suppresses glioma growth.

Blanchart A; Fernando R; Häring M; Assaife-Lopes N; Romanov RA; Andäng M; Harkany T; Ernfors P

Article: NATURE NEUROSCIENCE. 2017;20(2):176-188

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.

Romanov RA; Zeisel A; Bakker J; Girach F; Hellysaz A; Tomer R; Alpár A; Mulder J; Clotman F; Keimpema E; Hsueh B; Crow AK; Martens H; Schwindling C; Calvigioni D; Bains JS; Máté Z; Szabó G; Yanagawa Y; Zhang M-D; Rendeiro A; Farlik M; Uhlén M; Wulff P; Bock C; Broberger C; Deisseroth K; Hökfelt T; Linnarsson S; Horvath TL; Harkany T

Article: CELL. 2017;168(1-2):86-100.e15

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity.

Li J; Casteels T; Frogne T; Ingvorsen C; Honoré C; Courtney M; Huber KVM; Schmitner N; Kimmel RA; Romanov RA; Sturtzel C; Lardeau C-H; Klughammer J; Farlik M; Sdelci S; Vieira A; Avolio F; Briand F; Baburin I; Májek P; Pauler FM; Penz T; Stukalov A; Gridling M; Parapatics K; Barbieux C; Berishvili E; Spittler A; Colinge J; Bennett KL; Hering S; Sulpice T; Bock C; Distel M; Harkany T; Meyer D; Superti-Furga G; Collombat P; Hecksher-Sørensen J; Kubicek S

Editorial comment: CELL METABOLISM. 2017;25(1):8-10

(S)Pot on Mitochondria: Cannabinoids Disrupt Cellular Respiration to Limit Neuronal Activity.

Harkany T; Horvath TL

Article: NEUROPEPTIDES. 2016;60:37-44

Nonsulfated cholecystokinins in cerebral neurons.

Agersnap M; Zhang M-D; Harkany T; Hökfelt T; Rehfeld JF

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(43):E6686-E6695

Orthopedic surgery modulates neuropeptides and BDNF expression at the spinal and hippocampal levels.

Zhang M-D; Barde S; Yang T; Lei B; Eriksson LI; Mathew JP; Andreska T; Akassoglou K; Harkany T; Hökfelt TGM; Terrando N

Corrigendum: BRAIN STRUCTURE & FUNCTION. 2016;221(7):3843

Erratum to: Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord.

Zhang M-D; Barde S; Szodorai E; Josephson A; Mitsios N; Watanabe M; Attems J; Lubec G; Kovács GG; Uhlén M; Mulder J; Harkany T; Hökfelt T

Article: BRAIN STRUCTURE & FUNCTION. 2016;221(7):3803-3823

Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord.

Zhang M-D; Barde S; Szodorai E; Josephson A; Mitsios N; Watanabe M; Attems J; Lubec G; Kovács GG; Uhlén M; Mulder J; Harkany T; Hökfelt T

Article: SCIENCE. 2016;352(6291):1326-1329

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system.

Marques S; Zeisel A; Codeluppi S; van Bruggen D; Mendanha Falcão A; Xiao L; Li H; Häring M; Hochgerner H; Romanov RA; Gyllborg D; Muñoz Manchado A; La Manno G; Lönnerberg P; Floriddia EM; Rezayee F; Ernfors P; Arenas E; Hjerling-Leffler J; Harkany T; Richardson WD; Linnarsson S; Castelo-Branco G

Article: BRAIN STRUCTURE & FUNCTION. 2016;221(4):2061-2074

Cannabinoid receptor-interacting protein Crip1a modulates CB1 receptor signaling in mouse hippocampus.

Guggenhuber S; Alpar A; Chen R; Schmitz N; Wickert M; Mattheus T; Harasta AE; Purrio M; Kaiser N; Elphick MR; Monory K; Kilb W; Luhmann HJ; Harkany T; Lutz B; Klugmann M

Review: BIOLOGICAL PSYCHIATRY. 2016;79(7):e33-e45

At the Tip of an Iceberg: Prenatal Marijuana and Its Possible Relation to Neuropsychiatric Outcome in the Offspring.

Alpár A; Di Marzo V; Harkany T

Article: NATURE BIOTECHNOLOGY. 2016;34(2):175-183

Integration of electrophysiological recordings with single-cell RNA-seq data identifies neuronal subtypes.

Fuzik J; Zeisel A; Máté Z; Calvigioni D; Yanagawa Y; Szabó G; Linnarsson S; Harkany T

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016;113(3):E368-E377

H1N1 influenza virus induces narcolepsy-like sleep disruption and targets sleep-wake regulatory neurons in mice.

Tesoriero C; Codita A; Zhang M-D; Cherninsky A; Karlsson H; Grassi-Zucconi G; Bertini G; Harkany T; Ljungberg K; Liljeström P; Hökfelt TGM; Bentivoglio M; Kristensson K

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(45):E6185-E6194

Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture.

Malenczyk K; Keimpema E; Piscitelli F; Calvigioni D; Björklund P; Mackie K; Di Marzo V; Hökfelt TGM; Dobrzyn A; Harkany T

Article: NEUROCHEMISTRY INTERNATIONAL. 2015;90:72-84

Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents.

Bitencourt RM; Alpár A; Cinquina V; Ferreira SG; Pinheiro BS; Lemos C; Ledent C; Takahashi RN; Sialana FJ; Lubec G; Cunha RA; Harkany T; Köfalvi A

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2015;112(31):E4326-E4335

Replacing SNAP-25b with SNAP-25a expression results in metabolic disease.

Valladolid-Acebes I; Daraio T; Brismar K; Harkany T; Ögren SO; Hökfelt TGM; Bark C

Article: JOURNAL OF DENTAL RESEARCH. 2015;94(7):945-954

Three-dimensional Imaging Reveals New Compartments and Structural Adaptations in Odontoblasts.

Khatibi Shahidi M; Krivanek J; Kaukua N; Ernfors P; Hladik L; Kostal V; Masich S; Hampl A; Chubanov V; Gudermann T; Romanov RA; Harkany T; Adameyko I; Fried K

Article: SCIENTIFIC REPORTS. 2015;5:11592

Protracted brain development in a rodent model of extreme longevity.

Penz OK; Fuzik J; Kurek AB; Romanov R; Larson J; Park TJ; Harkany T; Keimpema E

Article: ACTA NEUROPATHOLOGICA. 2015;129(4):541-563

Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer's disease.

Ádori C; Glück L; Barde S; Yoshitake T; Kovacs GG; Mulder J; Maglóczky Z; Havas L; Bölcskei K; Mitsios N; Uhlén M; Szolcsányi J; Kehr J; Rönnbäck A; Schwartz T; Rehfeld JF; Harkany T; Palkovits M; Schulz S; Hökfelt T

Article: BRITISH JOURNAL OF PHARMACOLOGY. 2015;172(4):1074-1086

Presynaptic adenosine A2A receptors dampen cannabinoid CB1 receptor-mediated inhibition of corticostriatal glutamatergic transmission.

Ferreira SG; Gonçalves FQ; Marques JM; Tomé ÂR; Rodrigues RJ; Nunes-Correia I; Ledent C; Harkany T; Venance L; Cunha RA; Köfalvi A

Article: EMBO JOURNAL. 2015;34(1):36-54

A secretagogin locus of the mammalian hypothalamus controls stress hormone release.

Romanov RA; Alpár A; Zhang M-D; Zeisel A; Calas A; Landry M; Fuszard M; Shirran SL; Schnell R; Dobolyi Á; Oláh M; Spence L; Mulder J; Martens H; Palkovits M; Uhlen M; Sitte HH; Botting CH; Wagner L; Linnarsson S; Hökfelt T; Harkany T

Article: CEREBRAL CORTEX. 2014;24(12):3277-3288

GABAergic terminals are a source of galanin to modulate cholinergic neuron development in the neonatal forebrain.

Keimpema E; Zheng K; Barde SS; Berghuis P; Dobszay MB; Schnell R; Mulder J; Luiten PGM; Xu ZD; Runesson J; Langel Ü; Lu B; Hökfelt T; Harkany T

Review: NATURE REVIEWS NEUROSCIENCE. 2014;15(12):786-801

Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies.

Maccarrone M; Guzmán M; Mackie K; Doherty P; Harkany T

Review: EUROPEAN CHILD & ADOLESCENT PSYCHIATRY. 2014;23(10):931-941

Neuronal substrates and functional consequences of prenatal cannabis exposure.

Calvigioni D; Hurd YL; Harkany T; Keimpema E

Article: NATURE COMMUNICATIONS. 2014;5:4421

Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling.

Alpár A; Tortoriello G; Calvigioni D; Niphakis MJ; Milenkovic I; Bakker J; Cameron GA; Hanics J; Morris CV; Fuzik J; Kovacs GG; Cravatt BF; Parnavelas JG; Andrews WD; Hurd YL; Keimpema E; Harkany T

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(24):E2472-E2481

The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels.

Iannotti FA; Silvestri C; Mazzarella E; Martella A; Calvigioni D; Piscitelli F; Ambrosino P; Petrosino S; Czifra G; Bíró T; Harkany T; Taglialatela M; Di Marzo V

Article: EMBO JOURNAL. 2014;33(7):668-685

Miswiring the brain: Δ9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway.

Tortoriello G; Morris CV; Alpar A; Fuzik J; Shirran SL; Calvigioni D; Keimpema E; Botting CH; Reinecke K; Herdegen T; Courtney M; Hurd YL; Harkany T

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(12):E1149-E1158

Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury.

Zhang M-D; Tortoriello G; Hsueh B; Tomer R; Ye L; Mitsios N; Borgius L; Grant G; Kiehn O; Watanabe M; Uhlén M; Mulder J; Deisseroth K; Harkany T; Hökfelt TGM

Editorial comment: EUROPEAN JOURNAL OF NEUROSCIENCE. 2014;39(3):331-333

Neurotrophin and endocannabinoid interactions in the neurobiology of pain.

Harkany T; Zeilhofer HU; Cattaneo A

Review: EUROPEAN JOURNAL OF NEUROSCIENCE. 2014;39(3):334-343

The molecular interplay between endocannabinoid and neurotrophin signals in the nervous system and beyond.

Keimpema E; Hökfelt T; Harkany T; Doherty P

Article: BRAIN BEHAVIOR AND EVOLUTION. 2014;83(2):82-92

Revival of calcium-binding proteins for neuromorphology: secretagogin typifies distinct cell populations in the avian brain.

Gáti G; Lendvai D; Hökfelt T; Harkany T; Alpár A

Article: BIOCHEMICAL SOCIETY TRANSACTIONS. 2013;41(6):1569-1576

Endocannabinoid signals in the developmental programming of delayed-onset neuropsychiatric and metabolic illnesses.

Keimpema E; Calvigioni D; Harkany T

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(45):32685-32699

CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release.

Malenczyk K; Jazurek M; Keimpema E; Silvestri C; Janikiewicz J; Mackie K; Di Marzo V; Redowicz MJ; Harkany T; Dobrzyn A

Editorial comment: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(24):9625-9626

Orexin neurons use endocannabinoids to break obesity-induced inhibition.

Alpár A; Harkany T

Article: JOURNAL OF NEUROCHEMISTRY. 2013;125(1):157-171

Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease.

Zilberter M; Ivanov A; Ziyatdinova S; Mukhtarov M; Malkov A; Alpár A; Tortoriello G; Botting CH; Fülöp L; Osypov AA; Pitkänen A; Tanila H; Harkany T; Zilberter Y

Article: ACTA NEUROPATHOLOGICA. 2013;125(2):215-229

Neurochemical mapping of the human hippocampus reveals perisynaptic matrix around functional synapses in Alzheimer's disease.

Lendvai D; Morawski M; Négyessy L; Gáti G; Jäger C; Baksa G; Glasz T; Attems J; Tanila H; Arendt T; Harkany T; Alpár A

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(5):1935-1940

Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons.

Keimpema E; Tortoriello G; Alpár A; Capsoni S; Arisi I; Calvigioni D; Hu SS-J; Cattaneo A; Doherty P; Mackie K; Harkany T

Article: PLOS ONE. 2013;8(7):e67865

Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides.

Tortoriello G; Rhodes BP; Takacs SM; Stuart JM; Basnet A; Raboune S; Widlanski TS; Doherty P; Harkany T; Bradshaw HB

Article: SCIENTIFIC REPORTS. 2013;3:2093

Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling.

Keimpema E; Alpár A; Howell F; Malenczyk K; Hobbs C; Hurd YL; Watanabe M; Sakimura K; Kano M; Doherty P; Harkany T

Article: MOLECULAR PAIN. 2012;8:80

Secretagogin is expressed in sensory CGRP neurons and in spinal cord of mouse and complements other calcium-binding proteins, with a note on rat and human.

Shi T-JS; Xiang Q; Zhang M-D; Tortoriello G; Hammarberg H; Mulder J; Fried K; Wagner L; Josephson A; Uhlén M; Harkany T; Hökfelt T

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(16):6259-6264

Clusters of secretagogin-expressing neurons in the aged human olfactory tract lack terminal differentiation.

Attems J; Alpar A; Spence L; McParland S; Heikenwalder M; Uhlén M; Tanila H; Hökfelt TGM; Harkany T

Article: BRAIN RESEARCH BULLETIN. 2012;87(6):504-510

The decrease of dopamine D₂/D₃ receptor densities in the putamen and nucleus caudatus goes parallel with maintained levels of CB₁ cannabinoid receptors in Parkinson's disease: a preliminary autoradiographic study with the selective dopamine D₂/D₃ antagonist [³H]raclopride and the novel CB₁ inverse agonist [¹²⁵I]SD7015.

Farkas S; Nagy K; Jia Z; Harkany T; Palkovits M; Donohou SR; Pike VW; Halldin C; Máthé D; Csiba L; Gulyás B

Review: JOURNAL OF PHYSIOLOGY-LONDON. 2012;590(4):703-714

Sticking out of the crowd: the molecular identity and development of cholecystokinin-containing basket cells.

Keimpema E; Straiker A; Mackie K; Harkany T; Hjerling-Leffler J

Article: JOURNAL OF NEUROSCIENCE. 2012;32(6):1989-2001

Cracking down on inhibition: selective removal of GABAergic interneurons from hippocampal networks.

Antonucci F; Alpár A; Kacza J; Caleo M; Verderio C; Giani A; Martens H; Chaudhry FA; Allegra M; Grosche J; Michalski D; Erck C; Hoffmann A; Harkany T; Matteoli M; Härtig W

Article: NEUROCHEMISTRY INTERNATIONAL. 2012;60(3):286-291

[¹²⁵I]SD-7015 reveals fine modalities of CB₁ cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer's disease.

Farkas S; Nagy K; Palkovits M; Kovács GG; Jia Z; Donohue S; Pike V; Halldin C; Máthé D; Harkany T; Gulyás B; Csiba L

Review: CELLULAR SIGNALLING. 2012;24(2):378-387

The renaissance of Ca2+-binding proteins in the nervous system: secretagogin takes center stage.

Alpár A; Attems J; Mulder J; Hökfelt T; Harkany T

Editorial comment: EUROPEAN JOURNAL OF NEUROSCIENCE. 2011;34(10):1513-1515

Molecular mechanisms of neuronal specification.

Harkany T

Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2011;32(9):551-561

Molecular model of cannabis sensitivity in developing neuronal circuits.

Keimpema E; Mackie K; Harkany T

Article: BRAIN. 2011;134(Pt 4):1041-1060

Molecular reorganization of endocannabinoid signalling in Alzheimer's disease.

Mulder J; Zilberter M; Pasquaré SJ; Alpár A; Schulte G; Ferreira SG; Köfalvi A; Martín-Moreno AM; Keimpema E; Tanila H; Watanabe M; Mackie K; Hortobágyi T; de Ceballos ML; Harkany T

Article: GLIA. 2011;59(1):119-131

WNT signaling in activated microglia is proinflammatory.

Halleskog C; Mulder J; Dahlström J; Mackie K; Hortobágyi T; Tanila H; Kumar Puli L; Färber K; Harkany T; Schulte G

Article: JOURNAL OF NEUROSCIENCE. 2010;30(42):13992-14007

Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding.

Keimpema E; Barabas K; Morozov YM; Tortoriello G; Torii M; Cameron G; Yanagawa Y; Watanabe M; Mackie K; Harkany T

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(37):16336-16341

En masse in vitro functional profiling of the axonal mechanosensitivity of sensory neurons.

Usoskin D; Zilberter M; Linnarsson S; Hjerling-Leffler J; Uhlén P; Harkany T; Ernfors P

Published conference paper: EUROPEAN JOURNAL OF NEUROSCIENCE. 2010;31(12):2166-2177

Secretagogin is a Ca2+-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon.

Mulder J; Spence L; Tortoriello G; Dinieri JA; Uhlén M; Shui B; Kotlikoff MI; Yanagawa Y; Aujard F; Hökfelt T; Hurd YL; Harkany T

Editorial comment: EUROPEAN JOURNAL OF NEUROSCIENCE. 2010;31(9):1519-1520

HDAC9 links epigenetics to dendrite development (commentary on Sugo et al.).

Harkany T

Article: FRONTIERS IN NEUROANATOMY. 2010;4:1

SAT1, A Glutamine Transporter, is Preferentially Expressed in GABAergic Neurons.

Solbu TT; Bjørkmo M; Berghuis P; Harkany T; Chaudhry FA

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(52):22492-22497

Secretagogin is a Ca2+-binding protein specifying subpopulations of telencephalic neurons.

Mulder J; Zilberter M; Spence L; Tortoriello G; Uhlén M; Yanagawa Y; Aujard F; Hökfelt T; Harkany T

Article: CEREBRAL CORTEX. 2009;19(10):2308-2320

Input specificity and dependence of spike timing-dependent plasticity on preceding postsynaptic activity at unitary connections between neocortical layer 2/3 pyramidal cells.

Zilberter M; Holmgren C; Shemer I; Silberberg G; Grillner S; Harkany T; Zilberter Y

Review: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE. 2009;259(7):395-412

Neurobiological consequences of maternal cannabis on human fetal development and its neuropsychiatric outcome.

Jutras-Aswad D; DiNieri JA; Harkany T; Hurd YL

Review: CEREBRAL CORTEX. 2009;19(5):1092-1106

System A transporter SAT2 mediates replenishment of dendritic glutamate pools controlling retrograde signaling by glutamate.

Jenstad M; Quazi AZ; Zilberter M; Haglerød C; Berghuis P; Saddique N; Goiny M; Buntup D; Davanger S; S Haug F-M; Barnes CA; McNaughton BL; Ottersen OP; Storm-Mathisen J; Harkany T; Chaudhry FA

Article: JOURNAL OF NEUROSCIENCE. 2009;29(11):3453-3462

Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy.

Minkeviciene R; Rheims S; Dobszay MB; Zilberter M; Hartikainen J; Fülöp L; Penke B; Zilberter Y; Harkany T; Pitkänen A; Tanila H

Review: JOURNAL OF COMPARATIVE NEUROLOGY. 2009;513(1):1-20

Autoantibodies in autoimmune polyglandular syndrome type I patients react with major brain neurotransmitter systems.

Fetissov SO; Bensing S; Mulder J; Le Maitre E; Hulting A-L; Harkany T; Ekwall O; Sköldberg F; Husebye ES; Perheentupa J; Rorsman F; Kämpe O; Hökfelt T

Review: NEUROSCIENCE. 2009;158(1):223-230

The synaptic split of SNAP-25: different roles in glutamatergic and GABAergic neurons?

Matteoli M; Pozzi D; Grumelli C; Condliffe SB; Frassoni C; Harkany T; Verderio C

Article: JOURNAL OF NEUROSCIENCE. 2008;28(49):13125-13131

Unique luminal localization of VGAT-C terminus allows for selective labeling of active cortical GABAergic synapses.

Martens H; Weston MC; Boulland J-L; Grønborg M; Grosche J; Kacza J; Hoffmann A; Matteoli M; Takamori S; Harkany T; Chaudhry FA; Rosenmund C; Erck C; Jahn R; Härtig W

Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 2008;39(3):314-323

Calpain activity contributes to the control of SNAP-25 levels in neurons.

Grumelli C; Berghuis P; Pozzi D; Caleo M; Antonucci F; Bonanno G; Carmignoto G; Dobszay MB; Harkany T; Matteoli M; Verderio C

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(25):8760-8765

Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning.

Mulder J; Aguado T; Keimpema E; Barabás K; Ballester Rosado CJ; Nguyen L; Monory K; Marsicano G; Di Marzo V; Hurd YL; Guillemot F; Mackie K; Lutz B; Guzmán M; Lu H-C; Galve-Roperh I; Harkany T

Review: CURRENT OPINION IN NEUROBIOLOGY. 2008;18(3):338-345

Wiring and firing neuronal networks: endocannabinoids take center stage.

Harkany T; Mackie K; Doherty P

Article: MOLECULAR BIOLOGY OF THE CELL. 2008;19(5):2101-2112

Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro.

Martin MG; Perga S; Trovò L; Rasola A; Holm P; Rantamäki T; Harkany T; Castrén E; Chiara F; Dotti CG

Published conference paper: MOLECULAR AND CELLULAR ENDOCRINOLOGY. 2008;286(1-2 Suppl 1):S84-S90

Endocannabinoid functions controlling neuronal specification during brain development.

Harkany T; Keimpema E; Barabás K; Mulder J

Article: SCIENCE. 2007;316(5828):1212-1216

Hardwiring the brain: endocannabinoids shape neuronal connectivity.

Berghuis P; Rajnicek AM; Morozov YM; Ross RA; Mulder J; Urbán GM; Monory K; Marsicano G; Matteoli M; Canty A; Irving AJ; Katona I; Yanagawa Y; Rakic P; Lutz B; Mackie K; Harkany T

Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2007;28(2):83-92

The emerging functions of endocannabinoid signaling during CNS development.

Harkany T; Guzmán M; Galve-Roperh I; Berghuis P; Devi LA; Mackie K

Article: DEVELOPMENTAL NEUROBIOLOGY. 2006;66(13):1437-1451

Brain-derived neurotrophic factor selectively regulates dendritogenesis of parvalbumin-containing interneurons in the main olfactory bulb through the PLCgamma pathway.

Berghuis P; Agerman K; Dobszay MB; Minichiello L; Harkany T; Ernfors P

Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2006;23(8):2035-2047

Non-fibrillar beta-amyloid abates spike-timing-dependent synaptic potentiation at excitatory synapses in layer 2/3 of the neocortex by targeting postsynaptic AMPA receptors.

Shemer I; Holmgren C; Min R; Fülöp L; Zilberter M; Sousa KM; Farkas T; Härtig W; Penke B; Burnashev N; Tanila H; Zilberter Y; Harkany T

Published conference paper: INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. 2006;24(2-3):195-201

Thioflavins released from nanoparticles target fibrillar amyloid beta in the hippocampus of APP/PS1 transgenic mice.

Siegemund T; Paulke B-R; Schmiedel H; Bordag N; Hoffmann A; Harkany T; Tanila H; Kacza J; Härtig W

Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2006;23(4):1063-1070

Vesicular glutamate transporter 3 (VGLUT3) identifies spatially segregated excitatory terminals in the rat substantia nigra.

Martín-Ibañez R; Jenstad M; Berghuis P; Edwards RH; Hioki H; Kaneko T; Mulder J; Canals JM; Ernfors P; Chaudhry FA; Harkany T

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(52):19115-19120

Endocannabinoids regulate interneuron migration and morphogenesis by transactivating the TrkB receptor.

Berghuis P; Dobszay MB; Wang X; Spano S; Ledda F; Sousa KM; Schulte G; Ernfors P; Mackie K; Paratcha G; Hurd YL; Harkany T

Article: BEHAVIOURAL BRAIN RESEARCH. 2005;163(1):33-41

Galantamine-induced behavioral recovery after sublethal excitotoxic lesions to the rat medial septum.

Mulder J; Harkany T; Czollner K; Cremers TIFH; Keijser JN; Nyakas C; Luiten PGM

Review: NEUROSCIENTIST. 2005;11(4):334-344

Dendritic release of retrograde messengers controls synaptic transmission in local neocortical networks.

Zilberter Y; Harkany T; Holmgren CD

Article: NEUROSCIENCE. 2005;135(2):595-609

Redistribution of CB1 cannabinoid receptors during evolution of cholinergic basal forebrain territories and their cortical projection areas: a comparison between the gray mouse lemur (Microcebus murinus, primates) and rat.

Harkany T; Dobszay MB; Cayetanot F; Härtig W; Siegemund T; Aujard F; Mackie K

Published conference paper: INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE. 2004;22(7):533-543

Turning the heterogeneous into homogeneous: studies on selectively isolated GABAergic interneuron subsets.

Berghuis P; Dobszay MB; Ibanez RM; Ernfors P; Harkany T

Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2004;20(5):1290-1306

Brain-derived neurotrophic factor controls functional differentiation and microcircuit formation of selectively isolated fast-spiking GABAergic interneurons.

Berghuis P; Dobszay MB; Sousa KM; Schulte G; Mager PP; Härtig W; Görcs TJ; Zilberter Y; Ernfors P; Harkany T

Article: JOURNAL OF NEUROSCIENCE. 2004;24(21):4978-4988

Endocannabinoid-independent retrograde signaling at inhibitory synapses in layer 2/3 of neocortex: involvement of vesicular glutamate transporter 3.

Harkany T; Holmgren C; Härtig W; Qureshi T; Chaudhry FA; Storm-Mathisen J; Dobszay MB; Berghuis P; Schulte G; Sousa KM; Fremeau RT; Edwards RH; Mackie K; Ernfors P; Zilberter Y

Article: JOURNAL OF NEUROCHEMISTRY. 2004;88(5):1229-1239

Region-specific generation of functional neurons from naive embryonic stem cells in adult brain.

Harkany T; Andäng M; Kingma HJ; Görcs TJ; Holmgren CD; Zilberter Y; Ernfors P

Article: JOURNAL OF COMPARATIVE NEUROLOGY. 2003;465(1):1-10

Complementary distribution of vesicular glutamate transporters 1 and 2 in the nucleus accumbens of rat: Relationship to calretinin-containing extrinsic innervation and calbindin-immunoreactive neurons.

Härtig W; Riedel A; Grosche J; Edwards RH; Fremeau RT; Harkany T; Brauer K; Arendt T

Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2003;18(7):1979-1992

Complementary distribution of type 1 cannabinoid receptors and vesicular glutamate transporter 3 in basal forebrain suggests input-specific retrograde signalling by cholinergic neurons.

Harkany T; Härtig W; Berghuis P; Dobszay MB; Zilberter Y; Edwards RH; Mackie K; Ernfors P

Article: JOURNAL OF PHYSIOLOGY-LONDON. 2003;551(Pt 1):139-153

Pyramidal cell communication within local networks in layer 2/3 of rat neocortex.

Holmgren C; Harkany T; Svennenfors B; Zilberter Y