Genetiska mekanismer för åldrande – Maria Erikssons forskargrupp

Publikationer

Utvalda publikationer

• Editorial comment: EUROPEAN HEART JOURNAL. 2023;44(40):4208-4210

  Somatic mutations in vascular wall function and age-associated disease

  Revechon G; Merino LG; Machtel P; Eriksson M
• Editorial comment: CIRCULATION. 2023;147(23):1745-1747

  Readily Available Tools to Detect Progerin and Cardiac Disease Progression in Hutchinson-Gilford Progeria Syndrome

  Eriksson M; Haugaa K; Revechon G
• Editorial comment: NATURE REVIEWS GENETICS. 2022;23(11):645-646

  Reverting to old theories of ageing with new evidence for the role of somatic mutations

  Franco I; Eriksson M
• Article: NATURE COMMUNICATIONS. 2022;13(1):3068

  Transient expression of an adenine base editor corrects the Hutchinson-Gilford progeria syndrome mutation and improves the skin phenotype in mice

  Whisenant D; Lim K; Revechon G; Yao H; Bergo MO; Machtel P; Kim J-S; Eriksson M
• Editorial comment: AGING CELL. 2022;21(5):e13613

  Challenges of proving a causal role of somatic mutations in the aging process

  Franco I; Revechon G; Eriksson M
• Editorial comment: NEW ENGLAND JOURNAL OF MEDICINE. 2021;384(14):1364-1366

  Base Editing in Progeria

  Kim J-S; Eriksson M
• Editorial comment: NATURE MEDICINE. 2021;27(3):377-379

  Splice-inhibition therapy targets progeria

  Revechon G; Whisenant D; Eriksson M
• Article: GENOME BIOLOGY. 2019;20(1):285

  Whole genome DNA sequencing provides an atlas of somatic mutagenesis in healthy human cells and identifies a tumor-prone cell type

  Franco I; Helgadottir HT; Moggio A; Larsson M; Vrtacnik P; Johansson A; Norgren N; Lundin P; Mas-Ponte D; Nordstrom J; Lundgren T; Stenvinkel P; Wennberg L; Supek F; Eriksson M
• Article: AGING CELL. 2019;18(6):e13010

  Analysis of somatic mutations identifies signs of selection during in vitro aging of primary dermal fibroblasts

  Narisu N; Rothwell R; Vrtacnik P; Rodriguez S; Didion J; Zollner S; Erdos MR; Collins FS; Eriksson M
• Article: NATURE COMMUNICATIONS. 2019;10(1):4990

  Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson-Gilford Progeria Syndrome

  Aguado J; Sola-Carvajal A; Cancila V; Revechon G; Ong PF; Jones-Weinert CW; Arzt EW; Lattanzi G; Dreesen O; Tripodo C; Rossiello F; Eriksson M; di Fagagna FD
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(11):2272-2280.e12

  Accumulation of Progerin Affects the Symmetry of Cell Division and Is Associated with Impaired Wnt Signaling and the Mislocalization of Nuclear Envelope Proteins

  Sola-Carvajal A; Revechon G; Helgadottir HT; Whisenant D; Hagblom R; Dohla J; Katajisto P; Brodin D; Fagerstrom-Billai F; Viceconte N; Eriksson M
• Article: HUMAN MOLECULAR GENETICS. 2019;28(16):2675-2685

  Somatic mutation that affects transcription factor binding upstream of CD55 in the temporal cortex of a late-onset Alzheimer disease patient

  Helgadottir H; Lundin P; Arzt EW; Lindstrom A-K; Graff C; Eriksson M
• Article: JOURNAL OF CLINICAL INVESTIGATION. 2019;129(2):531-545

  Endothelial progerin expression causes cardiovascular pathology through an impaired mechanoresponse

  Osmanagic-Myers S; Kiss A; Manakanatas C; Hamza O; Sedlmayer F; Szabo PL; Fischer I; Fichtinger P; Podesser BK; Eriksson M; Foisner R
• Review: INTERNATIONAL REVIEW OF CELL AND MOLECULAR BIOLOGY. 2019;346:157-200

  Healthy skeletal muscle aging: The role of satellite cells, somatic mutations and exercise

  Franco I; Fernandez-Gonzalo R; Vrtacnik P; Lundberg TR; Eriksson M; Gustafsson T
• Article: NATURE COMMUNICATIONS. 2018;9(1):800

  Somatic mutagenesis in satellite cells associates with human skeletal muscle aging

  Franco I; Johansson A; Olsson K; Vrtacnik P; Lundin P; Helgadottir HT; Larsson M; Revechon G; Bosia C; Pagnani A; Provero P; Gustafsson T; Fischer H; Eriksson M
• Review: BIOCHEMICAL SOCIETY TRANSACTIONS. 2017;45(6):1279-1293

  Emerging candidate treatment strategies for Hutchinson-Gilford progeria syndrome

  Strandgren C; Revechon G; Sola-Carvajal A; Eriksson M
• Article: SCIENTIFIC REPORTS. 2017;7(1):4405

  Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time

  Revechon G; Viceconte N; McKenna T; Sola-Carvajal A; Vrtacnik P; Stenvinkel P; Lundgren T; Hultenby K; Franco I; Eriksson M

Medarbetare och kontakt

Gruppledare

• 

  Maria Eriksson

  Professor | Docent

  E-postadress maria.eriksson.2@ki.se

Alla medarbetare i gruppen

• 

  Matthieu Bardin

  Postdoktor

  E-postadress matthieu.bardin@ki.se
• 

  Maria Eriksson

  Professor | Docent

  E-postadress maria.eriksson.2@ki.se
• 

  Lara Garcia Merino

  Doktorand

  E-postadress lara.garcia.merino@ki.se
• 

  Quentin Giraud

  Postdoktorala Studier

  E-postadress quentin.giraud@ki.se
• 

  Gwladys Revêchon

  Anknuten till Forskning

  E-postadress gwladys.revechon@ki.se
• 

  Marianna Skipitari

  Postdoktor

  E-postadress marianna.skipitari@ki.se
• 

  Fabiana Stefani

  Doktorand

  E-postadress fabiana.stefani@ki.se