Molekylär neurovetenskap – Carlos Ibáñezs grupp

Publikationer

Utvalda publikationer

Article: EMBO JOURNAL. 2022;41(15):e110721
Convergent dopamine and ALK4 signaling to PCBP1 controls FosB alternative splicing and cocaine behavioral sensitization
Krapacher FA; Fernandez-Suarez D; Andersson A; Carrier-Ruiz A; Ibanez CF
Article: PLOS BIOLOGY. 2021;19(11):e3001350
Adult medial habenula neurons require GDNF receptor GFRα1 for synaptic stability and function
Fernandez-Suarez D; Krapacher FA; Pietrajtis K; Andersson A; Kisiswa L; Carrier-Ruiz A; Diana MA; Ibanez CF
Article: THE FASEB JOURNAL. 2021;35(8):e21759
Sustained anti-obesity effects of life-style change and anti-inflammatory interventions after conditional inactivation of the activin receptor ALK7.
Srivastava RK; Lee E-S; Sim E; Sheng NC; Ibáñez CF
Article: EMBO JOURNAL. 2021;40(2):e104450
Inactive variants of death receptor p75^NTR reduce Alzheimer's neuropathology by interfering with APP internalization
Yi C; Goh KY; Wong L-W; Ramanujan A; Tanaka K; Sajikumar S; Ibanez CF
Article: ELIFE. 2020;9:e54721
Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7.
Marmol P; Krapacher F; Ibáñez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2020;295(7):2034-2042
CD137 negatively affects ?browning? of white adipose tissue during cold exposure
Srivastava RK; Moliner A; Lee E-S; Nickles E; Sim E; Liu C; Schwarz H; Ibanez CF
Article: JOURNAL OF CELL BIOLOGY. 2020;219(1):e201905002
ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons
Gongrich C; Krapacher FA; Munguba H; Fernandez-Suarez D; Andersson A; Hjerling-Leffler J; Ibanez CF
Article: EMBO JOURNAL. 2019;38(5):e100989
Abnormal TDP-43 function impairs activity-dependent BDNF secretion, synaptic plasticity, and cognitive behavior through altered Sortilin splicing.
Tann JY; Wong L-W; Sajikumar S; Ibáñez CF
Article: CELL CHEMICAL BIOLOGY. 2018;25(12):1485-1494.e5
A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTR Induces Melanoma Cell Death and Reduces Tumor Growth.
Goh ETH; Lin Z; Ahn BY; Lopes-Rodrigues V; Dang NH; Salim S; Berger B; Dymock B; Senger DL; Ibáñez CF

Alla gruppmedlemmars publikationer

Review: THE FEBS JOURNAL. 2022;289(19):5776-5797
Regulation of metabolic homeostasis by the TGF-β superfamily receptor ALK7.
Ibáñez CF
Article: PLOS BIOLOGY. 2021;19(11):e3001350
Adult medial habenula neurons require GDNF receptor GFRα1 for synaptic stability and function
Fernandez-Suarez D; Krapacher FA; Pietrajtis K; Andersson A; Kisiswa L; Carrier-Ruiz A; Diana MA; Ibanez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2021;297(2):100916
Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains
Zhang N; Kisiswa L; Ramanujan A; Li Z; Sim EW; Tian X; Yuan W; Ibanez CF; Lin Z
Article: THE FASEB JOURNAL. 2021;35(8):e21759
Sustained anti-obesity effects of life-style change and anti-inflammatory interventions after conditional inactivation of the activin receptor ALK7.
Srivastava RK; Lee E-S; Sim E; Sheng NC; Ibáñez CF
Article: AGING CELL. 2021;20(2):e13305
Age-related changes in hippocampal-dependent synaptic plasticity and memory mediated by p75 neurotrophin receptor
Wong L-W; Chong YS; Lin W; Kisiswa L; Sim E; Ibanez CF; Sajikumar S
Article: EMBO JOURNAL. 2021;40(2):e104450
Inactive variants of death receptor p75^NTR reduce Alzheimer's neuropathology by interfering with APP internalization
Yi C; Goh KY; Wong L-W; Ramanujan A; Tanaka K; Sajikumar S; Ibanez CF
Review: CELL AND TISSUE RESEARCH. 2020;382(1):71-82
RET-independent signaling by GDNF ligands and GFRα receptors
Ibanez CF; Paratcha G; Ledda F
Article: ELIFE. 2020;9:e54721
Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7.
Marmol P; Krapacher F; Ibáñez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2020;295(7):2034-2042
CD137 negatively affects ?browning? of white adipose tissue during cold exposure
Srivastava RK; Moliner A; Lee E-S; Nickles E; Sim E; Liu C; Schwarz H; Ibanez CF
Article: JOURNAL OF CELL BIOLOGY. 2020;219(1):e201905002
ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons
Gongrich C; Krapacher FA; Munguba H; Fernandez-Suarez D; Andersson A; Hjerling-Leffler J; Ibanez CF
Corrigendum: CELL DEATH AND DISEASE. 2019;10(11):824
MAG induces apoptosis in cerebellar granule neurons through p75^NTR demarcating granule layer/white matter boundary (vol 10, 732, 2019)
Fernandez-Suarez D; Krapacher FA; Andersson A; Ibanez CF; Kisiswa L
Article: CELL DEATH AND DISEASE. 2019;10(10):732
MAG induces apoptosis in cerebellar granule neurons through p75^NTR demarcating granule layer/white matter boundary
Fernandez-Suarez D; Krapacher FA; Andersson A; Ibanez CF; Kisiswa L
Article: BIOLOGICAL REVIEWS. 2019;94(4):1282-1293
Death domain of p75 neurotrophin receptor: a structural perspective on an intracellular signalling hub.
Yuan W; Ibáñez CF; Lin Z
Article: JOURNAL OF NEUROSCIENCE. 2019;39(28):5452-5465
The p75 Neurotrophin Receptor Is an Essential Mediator of Impairments in Hippocampal-Dependent Associative Plasticity and Memory Induced by Sleep Deprivation.
Wong L-W; Tann JY; Ibanez CF; Sajikumar S
Article: EMBO JOURNAL. 2019;38(5):e100989
Abnormal TDP-43 function impairs activity-dependent BDNF secretion, synaptic plasticity, and cognitive behavior through altered Sortilin splicing.
Tann JY; Wong L-W; Sajikumar S; Ibáñez CF
Article: CELL CHEMICAL BIOLOGY. 2018;25(12):1485-1494.e5
A Small Molecule Targeting the Transmembrane Domain of Death Receptor p75NTR Induces Melanoma Cell Death and Reduces Tumor Growth.
Goh ETH; Lin Z; Ahn BY; Lopes-Rodrigues V; Dang NH; Salim S; Berger B; Dymock B; Senger DL; Ibáñez CF
Letter: DIABETES. 2018;67(12):e1
Comment on Bu et al. Insulin Regulates Lipolysis and Fat Mass by Upregulating Growth/Differentiation Factor 3 in Adipose Tissue Macrophages. Diabetes 2018;67:1761-1772.
Ibáñez CF
Article: CELL REPORTS. 2018;24(4):1013-1024
RIP2 Gates TRAF6 Interaction with Death Receptor p75^NTR to Regulate Cerebellar Granule Neuron Survival
Kisiswa L; Fernandez-Suarez D; Sergaki MC; Ibanez CF
Article: BIOLOGY OPEN. 2018;7(5):bio033753
Cell-autonomous role of GFRα1 in the development of olfactory bulb GABAergic interneurons
Zechel S; Fernandez-Suarez D; Ibanez CF
Article: CELL REPORTS. 2017;19(10):1977-1986
Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning
Sergaki MC; Carlos Lopez-Ramos J; Stagkourakis S; Gruart A; Broberger C; Maria Delgado-Garcia J; Ibanez CF
Article: CELL REPORTS. 2017;18(2):367-379
GFRα1 Regulates Purkinje Cell Migration by Counteracting NCAM Function.
Sergaki MC; Ibáñez CF
Review: NEUROBIOLOGY OF DISEASE. 2017;97(Pt B):80-89
Biology of GDNF and its receptors - Relevance for disorders of the central nervous system
Ibanez CF; Andressoo J-O
Article: ELIFE. 2016;5:e20770
Thalamo-cortical axons regulate the radial dispersion of neocortical GABAergic interneurons
Zechel S; Nakagawa Y; Ibanez CF
Article: JOURNAL OF NEUROSCIENCE. 2016;36(20):5587-5595
Death Domain Signaling by Disulfide-Linked Dimers of the p75 Neurotrophin Receptor Mediates Neuronal Death in the CNS.
Tanaka K; Kelly CE; Goh KY; Lim KB; Ibáñez CF
Article: ELIFE. 2015;4:e11692
Structural basis of death domain signaling in the p75 neurotrophin receptor.
Lin Z; Tann JY; Goh ETH; Kelly C; Lim KB; Gao JF; Ibanez CF
Article: JOURNAL OF CELL SCIENCE. 2015;128(8):1507-1517
Neuron-type-specific signaling by the p75NTR death receptor is regulated by differential proteolytic cleavage.
Vicario A; Kisiswa L; Tann JY; Kelly CE; Ibáñez CF
Article: ELIFE. 2014;3:e03245
Adipocyte ALK7 links nutrient overload to catecholamine resistance in obesity
Guo T; Marmol P; Moliner A; Bjornholm M; Zhang C; Shokat KM; Ibanez CF
Article: GENOME BIOLOGY. 2014;15(10):486
Topographical transcriptome mapping of the mouse medial ganglionic eminence by spatially resolved RNA-seq
Zechel S; Zajac P; Lonnerberg P; Ibanez CF; Linnarsson S
Article: DIABETOLOGIA. 2014;57(1):148-156
Differential regulation of mouse pancreatic islet insulin secretion and Smad proteins by activin ligands
Wu H; Mezghenna K; Marmol P; Guo T; Moliner A; Yang S-N; Berggren P-O; Ibanez CF
Article: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 2013;5(2):a009134
Structure and physiology of the RET receptor tyrosine kinase.
Ibáñez CF
Article: CELL REPORTS. 2012;2(6):1563-1570
Genetic dissection of neurotrophin signaling through the p75 neurotrophin receptor.
Charalampopoulos I; Vicario A; Pediaditakis I; Gravanis A; Simi A; Ibáñez CF
Article: THE FASEB JOURNAL. 2012;26(12):4966-4976
Neuroendocrine control of female reproductive function by the activin receptor ALK7
Sandoval-Guzman T; Gongrich C; Moliner A; Guo T; Wu H; Broberger C; Ibanez CF
Article: JOURNAL OF NEUROSCIENCE. 2012;32(48):17306-17320
Critical Role of GFRα1 in the Development and Function of the Main Olfactory System
Marks C; Belluscio L; Ibanez CF
Review: TRENDS IN NEUROSCIENCES. 2012;35(7):431-440
p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity.
Ibáñez CF; Simi A
Article: JOURNAL OF CELL SCIENCE. 2011;124(16):2797-2805
MET signaling in GABAergic neuronal precursors of the medial ganglionic eminence restricts GDNF activity in cells that express GFRα1 and a new transmembrane receptor partner
Perrinjaquet M; Sjostrand D; Moliner A; Zechel S; Lamballe F; Maina F; Ibanez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(41):31867-31875
Protein-tyrosine Phosphatase SHP2 Contributes to GDNF Neurotrophic Activity through Direct Binding to Phospho-Tyr⁶⁸⁷ in the RET Receptor Tyrosine Kinase
Perrinjaquet M; Vilar M; Ibanez CF
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):24-27
Beyond the cell surface: new mechanisms of receptor function.
Ibáñez CF
Article: DEVELOPMENTAL NEUROBIOLOGY. 2010;70(5):323-331
Assembly and activation of neurotrophic factor receptor complexes.
Simi A; Ibáñez CF
Article: JOURNAL OF CELL SCIENCE. 2009;122(18):3351-3357
Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor
Vilar M; Charalampopoulos I; Kenchappa RS; Reversi A; Klos-Applequist JM; Karaca E; Simi A; Spuch C; Choi S; Friedman WJ; Ericson J; Schiavo G; Carter BD; Ibanez CF
Article: JOURNAL OF NEUROSCIENCE. 2009;29(34):10695-10705
Regionalized loss of parvalbumin interneurons in the cerebral cortex of mice with deficits in GFRalpha1 signaling.
Canty AJ; Dietze J; Harvey M; Enomoto H; Milbrandt J; Ibáñez CF
Article: NEURON. 2009;62(1):72-83
Activation of the p75 Neurotrophin Receptor through Conformational Rearrangement of Disulphide-Linked Receptor Dimers
Vilar M; Charalampopoulos I; Kenchappa RS; Simi A; Karaca E; Reversi A; Choi S; Bothwell M; Mingarro I; Friedman WJ; Schiavo G; Bastiaens PIH; Verveer PJ; Carter BD; Ibanez CF
Editorial comment: NATURE NEUROSCIENCE. 2008;11(7):735-736
Catecholaminergic neuron survival: getting hooked on GDNF.
Ibáñez CF
Editorial comment: CURRENT OPINION IN NEUROBIOLOGY. 2008;18(3):229-231
Signalling mechanisms.
Ibanez CF; Häusser M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(20):7252-7256
Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity
Andersson O; Korach-Andre M; Reissmann E; Ibanez CF; Bertolino P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008;105(20):7246-7251
Activin B receptor ALK7 is a negative regulator of pancreatic β-cell function
Bertolino P; Holmberg R; Reissmann E; Andersson O; Berggren P-O; Ibanez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2008;283(20):13792-13798
Insights into GFRα1 regulation of neural cell adhesion molecule (NCAM) function from structure-function analysis of the NCAM/GFRα1 receptor complex
Sjostrand D; Ibanez CF
Article: STEM CELLS AND DEVELOPMENT. 2008;17(2):233-243
Mouse embryonic stem cell-derived spheres with distinct neurogenic potentials
Moliner A; Enfors P; Ibanez CF; Andang M
Article: NATURE. 2008;451(7177):460-464
Histone H2AX-dependent GABA_A receptor regulation of stem cell proliferation
Andang M; Hjerling-Leffler J; Moliner A; Lundgren TK; Castelo-Branco G; Nanou E; Pozas E; Bryja V; Halliez S; Nishimaru H; Wilbertz J; Arenas E; Koltzenburg M; Charnay P; El Manira A; Ibanez CF; Ernfors P
Article: NATURE PROTOCOLS. 2008;3(6):1013-1017
Optimized mouse ES cell culture system by suspension growth in a fully defined medium
Andang M; Moliner A; Doege CA; Ibanez CF; Ernfors P
Article: DEVELOPMENTAL BIOLOGY. 2007;311(2):500-511
Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development
Andersson O; Bertolino P; Ibanez CF
Review: TRENDS IN CELL BIOLOGY. 2007;17(11):519-528
Message in a bottle: long-range retrograde signaling in the nervous system.
Ibáñez CF
Editorial comment: NEURON. 2007;54(5):673-675
Hierarchical control of sensory neuron development by neurotrophic factors
Ibanez CF; Ernfors P
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2007;282(17):12734-12740
Disruption of the GDNF binding site in NCAM dissociates ligand binding and homophilic cell adhesion
Sjostrand D; Carlsson J; Paratcha G; Persson B; Ibanez CF
Article: NATURE NEUROSCIENCE. 2007;10(3):293-300
GDNF and GFRα1 promote formation of neuronal synapses by ligand-induced cell adhesion
Ledda F; Paratcha G; Sandoval-Guzman T; Ibanez CF
Article: ONCOGENE. 2006;25(53):7086-7095
Self-association of the transmembrane domain of RET underlies oncogenic activation by MEN2A mutations
Kjaer S; Kurokawa K; Perrinjaquet M; Abrescia C; Ibanez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(44):33577-33587
Structure and chemical inhibition of the RET tyrosine kinase domain.
Knowles PP; Murray-Rust J; Kjaer S; Scott RP; Hanrahan S; Santoro M; Ibáñez CF; McDonald NQ
Article: EMBO REPORTS. 2006;7(8):831-837
Growth differentiation factor 11 signals through the transforming growth factor-β receptor ALK5 to regionalize the anterior-posterior axis
Andersson O; Reissmann E; Ibanez CF
Article: DEVELOPMENTAL BIOLOGY. 2006;293(2):370-381
Synergistic interaction between Gdf1 and Nodal during anterior axis development
Andersson O; Reissmann E; Jornvall H; Ibanez CF
Article: CEREBRAL CORTEX. 2006;16(4):487-499
BDNF-modulated spatial organization of Cajal-Retzius and GABAergic neurons in the marginal zone plays a role in the development of cortical organization.
Alcántara S; Pozas E; Ibañez CF; Soriano E
Article: EMBO JOURNAL. 2006;25(6):1219-1230
Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle
Vilar M; Murillo-Carretero M; Mira H; Magnusson K; Besset V; Ibáñez CF
Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 2006;31(3):505-514
GDNF is a chemoattractant factor for neuronal precursor cells in the rostral migratory stream
Paratcha G; Ibáñez CF; Ledda F
Article: JOURNAL OF NEUROSCIENCE. 2005;25(37):8451-8456
Inhibitors of the mitogen-activated protein kinase kinase 1/2 signaling pathway clear prion-infected cells from PrP^Sc
Nordström EK; Luhr KM; Ibáñez C; Kristensson K
Article: FEBS LETTERS. 2005;579(17):3789-3796
Drosophila RET contains an active tyrosine kinase and elicits neurotrophic activities in mammalian cells
Abrescia C; Sjöstrand D; Kjaer S; Ibáñez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(14):13442-13449
Distinct turnover of alternatively spliced isoforms of the RET kinase receptor mediated by differential recruitment of the Cbl ubiquitin ligase
Scott RP; Eketjäll S; Aineskog H; Ibáñez CF
Article: NEURON. 2005;45(5):701-713
GDNF and GFRalpha1 promote differentiation and tangential migration of cortical GABAergic neurons.
Pozas E; Ibáñez CF
Article: NEUROSCIENCE. 2005;135(2):451-461
Disruption of ephrin-A/EphA binding alters synaptogenesis and neural connectivity in the hippocampus.
Martínez A; Otal R; Sieber B-A; Ibáñez C; Soriano E
Article: MOLECULAR AND CELLULAR BIOLOGY. 2004;24(21):9383-9389
ALK7, a receptor for nodal, is dispensable for embryogenesis and left-right patterning in the mouse
Jörnvall H; Reissmann E; Andersson O; Mehrkash M; Ibáñez CF
Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 2004;27(2):132-139
Retrograde propagation of GDNF-mediated signals in sympathetic neurons.
Coulpier M; Ibáñez CF
Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 2004;26(3):418-428
Disruption of EphA/ephrin-A signaling in the nigrostriatal system reduces dopaminergic innervation and dissociates behavioral responses to amphetamine and cocaine
Sieber BA; Kumin A; Canals JM; Danielsson A; Paratcha G; Arenas E; Alberch J; Ögren SO; Ibáñez CF
Editorial comment: NEURON. 2004;42(1):3-5
Lipid rafts as organizing platforms for cell chemotaxis and axon guidance.
Ibáñez CF
Letter: NATURE. 2004;427(6974):485
Framework reveals lack of basic-research funds.
Ibanez CF
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2004;61(4):488-496
Recent evolutionary origin within the primate lineage of two pseudogenes with similarity to members of the transforming growth factor-β superfamily
Eketjäll S; Jörnvall H; Lönnerberg P; Kobayashi S; Ibáñez CF
Article: DEVELOPMENT. 2003;130(24):6089-6099
Functional notch signaling is required for BMP4-induced inhibition of myogenic differentiation
Dahlqvist C; Blokzijl A; Chapman G; Falk A; Dannaeus K; Ibâñez CF; Lendahl U
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(48):47898-47904
Identification of a surface for binding to the GDNF-GFR alpha 1 complex in the first cadherin-like domain of RET.
Kjaer S; Ibáñez CF
Article: JOURNAL OF CELL BIOLOGY. 2003;163(4):723-728
Cross-talk between the Notch and TGF-β signaling pathways mediated by interaction of the Notch intracellular domain with Smad3
Blokzijl A; Dahlqvist C; Reissmann E; Falk A; Moliner A; Lendahl U; Ibáñez CF
Article: HUMAN MOLECULAR GENETICS. 2003;12(17):2133-2144
Intrinsic susceptibility to misfolding of a hot-spot for Hirschsprung disease mutations in the ectodomain of RET.
Kjaer S; Ibáñez CF
Article: CELL. 2003;113(7):867-879
The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family Ligands
Paratcha G; Ledda F; Ibáñez CF
Article: DEVELOPMENT. 2003;130(7):1267-1280
BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2.
Aguado F; Carmona MA; Pozas E; Aguiló A; Martínez-Guijarro FJ; Alcantara S; Borrell V; Yuste R; Ibañez CF; Soriano E
Article: NEURON. 2002;36(3):387-401
Target-derived GFRα1 as an attractive guidance signal for developing sensory and sympathetic axons via activation of Cdk5
Ledda F; Paratcha G; Ibáñez CF
Review: CURRENT OPINION IN NEUROBIOLOGY. 2002;12(5):542-549
Lipid rafts and the control of neurotrophic factor signaling in the nervous system:: variations on a theme
Paratcha G; Ibáñez CF
Article: TRENDS IN NEUROSCIENCES. 2002;25(6):284-286
Jekyll-Hyde neurotrophins: the story of proNGF.
Ibáñez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(20):18091-18097
Coaggregation, cointernalization, and codesensitization of adenosine A_2A receptors and dopamine D₂ receptors
Hillion J; Canals M; Torvinen M; Casadó V; Scott R; Terasmaa A; Hansson A; Watson S; Olah ME; Mallol J; Canela EI; Zoli M; Agnati LF; Ibáñez CF; Lluis C; Franco R; Ferré S; Fuxe K
Article: HUMAN MOLECULAR GENETICS. 2002;11(3):325-329
Functional characterization of mutations in the GDNF gene of patients with Hirschsprung disease
Eketjäll S; Ibáñez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(3):1991-1999
Coordinated activation of autophosphorylation sites in the RET receptor tyrosine kinase: importance of tyrosine 1062 for GDNF mediated neuronal differentiation and survival.
Coulpier M; Anders J; Ibáñez CF
Article: CURRENT BIOLOGY. 2002;12(1):35-45
Physical and functional interaction between GATA-3 and Smad3 allows TGF-beta regulation of GATA target genes.
Blokzijl A; ten Dijke P; Ibáñez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(38):35808-35817
Molecular modeling of the extracellular domain of the RET receptor tyrosine kinase reveals multiple cadherin-like domains and a calcium-binding site.
Anders J; Kjar S; Ibáñez CF
Other: TRENDS IN NEUROSCIENCES. 2001;24(8):429
Response:: GDNF recruits the signaling crew into lipid rafts
Ibáñez C
Article: GENES & DEVELOPMENT. 2001;15(15):2010-2022
The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development
Reissmann E; Jörnvall H; Blokzijl A; Andersson O; Chang C; Minchiotti G; Persico MG; Ibáñez CF; Brivanlou AH
Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 2001;18(1):56-67
Neuromuscular junction disassembly and muscle fatigue in mice lacking neurotrophin-4
Belluardo N; Westerblad H; Mudó G; Casabona A; Bruton J; Caniglia G; Pastoris O; Grassi F; Ibáñez CF
Article: THE FEBS JOURNAL. 2001;268(5):1382-1391
Structure-activity relationship of the p55 TNF receptor death domain and its lymphoproliferation mutants.
De Wilde G; Murray-Rust J; Boone E; Olerenshaw D; McDonald NQ; Ibanez C; Haegeman G; Wollmer A; Federwisch M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(7):5140-5146
The orphan receptor serine/threonine kinase ALK7 signals arrest of proliferation and morphological differentiation in a neuronal cell line
Jörnvall H; Blokzijl A; ten Dijke P; Ibáñez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(2):1450-1458
Determinants of ligand binding specificity in the glial cell line-derived neurotrophic factor family receptor alpha S.
Scott RP; Ibanez CF
Article: NEURON. 2001;29(1):171-184
Released GFRα1 potentiates downstream signaling, neuronal survival, and differentiation via a novel mechanism of recruitment of c-Ret to lipid rafts
Paratcha G; Ledda F; Baars L; Coulpier M; Besset V; Anders J; Scott R; Ibáñez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(50):39159-39166
Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
Besset V; Scott RP; Ibáñez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2000;275(50):39427-39434
Mammalian GFRalpha -4, a divergent member of the GFRalpha family of coreceptors for glial cell line-derived neurotrophic factor family ligands, is a receptor for the neurotrophic factor persephin.
Masure S; Cik M; Hoefnagel E; Nosrat CA; Van der Linden I; Scott R; Van Gompel P; Lesage AS; Verhasselt P; Ibáñez CF; Gordon RD
Article: DEVELOPMENT. 2000;127(21):4531-4540
Brain derived neurotrophic factor is an endothelial cell survival factor required for intramyocardial vessel stabilization
Donovan MJ; Lin MI; Wiegn P; Ringstedt T; Kraemer R; Hahn R; Wang S; Ibañez CF; Rafii S; Hempstead BL
Review: RESULTS AND PROBLEMS IN CELL DIFFERENTIATION. 2000;30:163-188
Neurotrophic factors: versatile signals for cell-cell communication in the nervous system.
Ibáñez CF
Article: EMBO JOURNAL. 1999;18(21):5901-5910
Distinct structure elements in GDNF mediate binding to GFRα1 and activation of the GFRα1-c-Ret receptor complex
Eketjäll S; Fainzilber M; Murray-Rust J; Ibáñez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(30):20885-20894
Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells.
Trupp M; Scott R; Whittemore SR; Ibáñez CF
Article: THE FEBS JOURNAL. 1999;263(2):305-311
An ethanol-inducible MDR ethanol dehydrogenase/acetaldehyde reductase in Escherichia coli -: Structural and enzymatic relationships to the eukaryotic protein forms
Shafqat J; Höög JO; Hjelmqvist L; Oppermann UCT; Ibáñez C; Jörnvall H
Article: MOLECULAR REPRODUCTION AND DEVELOPMENT. 1999;53(3):274-281
Novel, testis-specific mRNA transcripts encoding N-terminally truncated choline acetyltransferase
Lönnerberg P; Ibáñez CF
Article: JOURNAL OF NEUROSCIENCE. 1999;19(9):3507-3518
Role of brain-derived neurotrophic factor in target invasion in the gustatory system
Ringstedt T; Ibanez CF; Nosrat CA
Letter: NATURE. 1999;398(6725):280
Researchers face 'Catch-22' grants trap.
Ibáñez CF
Letter: TRENDS IN NEUROSCIENCES. 1999;22(3):109
Neurotrophic factors -: Reply
Ibáñez CF
Published conference paper: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 1999;463:285-293
Studies on variants of alcohol dehydrogenases and its domains
Shafqat J; Höög JO; Hjelmqvist L; Oppermann U; Ibanez C; Jörnvall H
Review: TRENDS IN NEUROSCIENCES. 1998;21(10):438-444
Emerging themes in structural biology of neurotrophic factors.
Ibáñez CF
Article: NEURON. 1998;21(2):305-315
BDNF regulates Reelin expression and Cajal-Retzius cell development in the cerebral cortex
Ringstedt T; Linnarsson S; Wagner J; Lendahl U; Kokaia Z; Arenas E; Ernfors P; Ibáñez CF
Article: MOLECULAR AND CELLULAR NEUROSCIENCE. 1998;11(1-2):47-63
Multiple GPI-anchored receptors control GDNF-dependent and independent activation of the c-Ret receptor tyrosine kinase.
Trupp M; Raynoschek C; Belluardo N; Ibáñez CF
Article: EMBO JOURNAL. 1998;17(9):2534-2542
Early evolutionary origin of the neurotrophin receptor family.
van Kesteren RE; Fainzilber M; Hauser G; van Minnen J; Vreugdenhil E; Smit AB; Ibáñez CF; Geraerts WP; Bulloch AG
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998;95(9):5269-5274
Targeted expression of a multifunctional chimeric neurotrophin in the lesioned sciatic nerve accelerates regeneration of sensory and motor axons
Funakoshi H; Risling M; Carlstedt T; Lendahl U; Timmusk T; Metsis M; Yamamoto Y; Ibáñez CF
Article: FEBS LETTERS. 1998;424(3):285-290
Neurotrophin-7:: a novel member of the neurotrophin family from the zebrafish
Nilsson AS; Fainzilber M; Falck P; Ibáñez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(52):33085-33091
A second determinant of binding to the p75 neurotrophin receptor revealed by alanine-scanning mutagenesis of a conserved loop in nerve growth factor
Rydén M; Ibáñez CF
Published conference paper: EUROPEAN JOURNAL OF CANCER. 1997;33(12):2058-2063
Coexpression of mRNA for the full-length neurotrophin receptor trk-C and trk-A in favourable neuroblastoma
Svensson T; Rydén M; Schilling FH; Dominici C; Sehgal R; Ibáñez CF; Kogner P
Letter: NEURON. 1997;19(3):485
Nomenclature of GPI-linked receptors for the GDNF ligand family
Davies AM; Dixon JE; Fox GM; Ibanez CF; Jing SQ; Johnson E; Milbrandt J; Phillips H; Rosenthal A; Saarma M; Sanicola M; Treanor J; Vega QC
Article: EMBO JOURNAL. 1997;16(16):4999-5005
NMR structure of the death domain of the p75 neurotrophin receptor.
Liepinsh E; Ilag LL; Otting G; Ibáñez CF
Article: DEVELOPMENT. 1997;124(13):2603-2613
Limb proprioceptive deficits without neuronal loss in transgenic mice overexpressing neurotrophin-3 in the developing nervous system
Ringstedt T; Kucera J; Lendahl U; Ernfors P; Ibanez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(26):16322-16328
Differential modulation of neuron survival during development by nerve growth factor binding to the p75 neurotrophin receptor
Ryden M; Hempstead B; Ibanez CF
Article: JOURNAL OF NEUROSCIENCE. 1997;17(10):3554-3567
Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS.
Trupp M; Belluardo N; Funakoshi H; Ibáñez CF
Article: JOURNAL OF MOLECULAR NEUROSCIENCE. 1997;8(1):29-44
On the role of the low-affinity neurotrophin receptor p75(LNTR) in nerve growth factor induction of differentiation and AP 1 binding activity in PC12 cells
Kontny E; Ciruela F; Svenningsson P; Ibanez CF; Fredholm BB
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(52):33358-33365
Cell type-specific regulation of choline acetyltransferase gene expression - Role of the neuron-restrictive silencer element and cholinergic-specific enhancer sequences
Lonnerberg P; Schoenherr CJ; Anderson DJ; Ibanez CF
Article: JOURNAL OF IMMUNOLOGY. 1996;157(12):5582-5588
Basophil priming by neurotrophic factors. Activation through the trk receptor.
Bürgi B; Otten UH; Ochensberger B; Rihs S; Heese K; Ehrhard PB; Ibanez CF; Dahinden CA
Article: SCIENCE. 1996;274(5292):1540-1543
CRNF, a molluscan neurotrophic factor that interacts with the p75 neurotrophin receptor.
Fainzilber M; Smit AB; Syed NI; Wildering WC; Hermann; van der Schors RC; Jiménez C; Li KW; van Minnen J; Bulloch AG; Ibáñez CF; Geraerts WP
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(48):30603-30609
A novel type I receptor serine-threonine kinase predominantly expressed in the adult central nervous system
Ryden M; Imamura T; Jornvall H; Belluardo N; Neveu I; Trupp M; Okadome T; tenDijke P; Ibanez CF
Article: BRITISH JOURNAL OF CANCER. 1996;74(5):773-779
Expression of mRNA for the neurotrophin receptor trkC in neuroblastomas with favourable tumour stage and good prognosis
Ryden M; Sehgal R; Dominici C; Schilling FH; Ibanez CF; Kogner P
Article: NEUROCHEMICAL RESEARCH. 1996;21(7):787-793
Neurotrophin-4: the odd one out in the neurotrophin family.
Ibáñez CF
Article: NATURE. 1996;381(6585):785-789
Functional receptor for GDNF encoded by the c-ret proto-oncogene
Trupp M; Arenas E; Fainzilber M; Nilsson AS; Sieber BA; Grigoriou M; Kilkenny C; SalazarGrueso E; Pachnis V; Arumae U; Sariola H; Saarma M; Ibanez CF
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(10):5623-5627
Binding of neurotrophin-3 to p75(LNGFR), TrkA, and TrkB mediated by a single functional epitope distinct from that recognized by TrkC
Ryden M; Ibanez CF
Article: NEURON. 1995;15(6):1465-1473
GDNF prevents degeneration and promotes the phenotype of brain noradrenergic neurons in vivo
Arenas E; Trupp M; Akerud P; Ibanez CF
Article: JOURNAL OF CELL BIOLOGY. 1995;130(1):137-148
PERIPHERAL EXPRESSION AND BIOLOGICAL-ACTIVITIES OF GDNF, A NEW NEUROTROPHIC FACTOR FOR AVIAN AND MAMMALIAN PERIPHERAL NEURONS
TRUPP M; RYDEN M; JORNVALL H; FUNAKOSHI H; TIMMUSK T; ARENAS E; IBANEZ CF
Article: SCIENCE. 1995;268(5216):1495-1499
MUSCLE-DERIVED NEUROTROPHIN-4 AS AN ACTIVITY-DEPENDENT TROPHIC SIGNAL FOR ADULT MOTOR-NEURONS
FUNAKOSHI H; BELLUARDO N; ARENAS E; YAMAMOTO Y; CASABONA A; PERSSON H; IBANEZ CF
Review: TRENDS IN BIOTECHNOLOGY. 1995;13(6):217-227
Neurotrophic factors: from structure-function studies to designing effective therapeutics.
Ibáñez CF
Review: LAKARTIDNINGEN. 1995;92(21):2191-2194
[Nerve growth factors in future therapies. Protein mutation broadens the range of therapeutic possibilities].
Ibáñez CF; Rydén M
Article: EMBO JOURNAL. 1995;14(9):1979-1990
FUNCTIONAL-ANALYSIS OF MUTANT NEUROTROPHINS DEFICIENT IN LOW-AFFINITY BINDING REVEALS A ROLE FOR P75(LNGFR) IN NT-4 SIGNALING
RYDEN M; MURRAYRUST J; GLASS D; ILAG LL; TRUPP M; YANCOPOULOS GD; MCDONALD NQ; IBANEZ CF
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995;92(9):4046-4050
REGULATORY REGION IN CHOLINE-ACETYLTRANSFERASE GENE DIRECTS DEVELOPMENTAL AND TISSUE-SPECIFIC EXPRESSION IN TRANSGENIC MICE
LONNERBERG P; LENDAHL U; FUNAKOSHI H; ARHLUNDRICHTER L; PERSSON H; IBANEZ CF
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1995;7(4):656-662
SYNERGISTIC TROPHIC ACTIONS ON RAT BASAL FOREBRAIN NEURONS REVEALED BY A SYNTHETIC NGF/BDNF CHIMERIC MOLECULE
FRIEDMAN WJ; BLACK IB; PERSSON H; IBANEZ CF
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995;92(2):607-611
PAN-NEUROTROPHIN-1 - A GENETICALLY-ENGINEERED NEUROTROPHIC FACTOR DISPLAYING MULTIPLE SPECIFICITIES IN PERIPHERAL NEURONS IN-VITRO AND IN-VIVO
ILAG LL; CURTIS R; GLASS D; FUNAKOSHI H; TOBKES NJ; RYAN TE; ACHESON A; LINDSAY RM; PERSSON H; YANCOPOULOS GD; DISTEFANO PS; IBANEZ CF
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