Extracellulära vesiklers roll i immunförsvaret – Forskargrupp Susanne Gabrielsson

Article: CANCER IMMUNOLOGY RESEARCH. 2023;11(2):217-227

Antigen-Loaded Extracellular Vesicles Induce Responsiveness to Anti-PD-1 and Anti-PD-L1 Treatment in a Checkpoint Refractory Melanoma Model.

Veerman RE; Akpinar GG; Offens A; Steiner L; Larssen P; Lundqvist A; Karlsson MCI; Gabrielsson S

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2021;10(9):e12128

Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin.

Veerman RE; Teeuwen L; Czarnewski P; Güclüler Akpinar G; Sandberg A; Cao X; Pernemalm M; Orre LM; Gabrielsson S; Eldh M

Article: CANCERS. 2021;13(13):3242

Proteomic Profiling of Tissue Exosomes Indicates Continuous Release of Malignant Exosomes in Urinary Bladder Cancer Patients, Even with Pathologically Undetectable Tumour.

Eldh M; Mints M; Hiltbrunner S; Ladjevardi S; Alamdari F; Johansson M; Jakubczyk T; Veerman RE; Winqvist O; Sherif A; Gabrielsson S

Article: SCIENTIFIC REPORTS. 2020;10(1):15328

Sarcoidosis exosomes stimulate monocytes to produce pro-inflammatory cytokines and CCL2.

Wahlund CJE; Gucluler Akpinar G; Steiner L; Ibrahim A; Bandeira E; Lepzien R; Lukic A; Smed-Sörensen A; Kullberg S; Eklund A; Grunewald J; Gabrielsson S

Article: SCIENTIFIC REPORTS. 2020;10(1):5960

Urinary Exosomes from Bladder Cancer Patients Show a Residual Cancer Phenotype despite Complete Pathological Downstaging.

Hiltbrunner S; Mints M; Eldh M; Rosenblatt R; Holmström B; Alamdari F; Johansson M; Veerman RE; Winqvist O; Sherif A; Gabrielsson S

Article: JOURNAL OF IMMUNOLOGY. 2019;203(4):825-834

Allogenicity Boosts Extracellular Vesicle-Induced Antigen-Specific Immunity and Mediates Tumor Protection and Long-Term Memory In Vivo.

Larssen P; Veerman RE; Akpinar GG; Hiltbrunner S; Karlsson MCI; Gabrielsson S

Article: CANCER LETTERS. 2019;444:1-8

Exosomes and cells from lung cancer pleural exudates transform LTC4 to LTD4, promoting cell migration and survival via CysLT1.

Lukic A; Wahlund CJE; Gómez C; Brodin D; Samuelsson B; Wheelock CE; Gabrielsson S; Rådmark O

Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(4):1186-1194

Pulmonary sarcoidosis is associated with exosomal vitamin D-binding protein and inflammatory molecules.

Martinez-Bravo M-J; Wahlund CJE; Qazi KR; Moulder R; Lukic A; Rådmark O; Lahesmaa R; Grunewald J; Eklund A; Gabrielsson S

Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):254

The impact of extracellular vesicles on inflammatory processes in pulmonary sarcoidosis

Wahlund C; Gucluler G; Lepzien R; Smed-Sorenssen A; Gabrielsson S

Conference publication: SCANDINAVIAN JOURNAL OF UROLOGY. 2017;51:38-39

Exosomes in urine retain a malignant protein profile after primary tumour ablation in patients with invasive urinary bladder cancer

Mints M; Hiltbrunner S; Eldh M; Rosenblatt R; Holmstrom B; Alamdari F; Johansson M; Hansson J; Vasko J; Winqvist O; Sherif A; Gabrielsson S

Article: JOURNAL OF LIPID RESEARCH. 2016;57(9):1659-1669

Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4.

Lukic A; Ji J; Idborg H; Samuelsson B; Palmberg L; Gabrielsson S; Rådmark O

Article: ONCOTARGET. 2016;7(25):38707-38717

Exosomal cancer immunotherapy is independent of MHC molecules on exosomes.

Hiltbrunner S; Larssen P; Eldh M; Martinez-Bravo M-J; Wagner AK; Karlsson MCI; Gabrielsson S

Article: CANCER RESEARCH. 2013;73(13):3865-3876

Synergistic induction of adaptive antitumor immunity by codelivery of antigen with α-galactosylceramide on exosomes.

Gehrmann U; Hiltbrunner S; Georgoudaki A-M; Karlsson MC; Näslund TI; Gabrielsson S

Conference publication: JOURNAL OF IMMUNOLOGY. 2013;190

Dendritic cell derived exosomes need to activate both T and B cells to induce antitumor immunity

Naslund T; Gehrmann U; Qazi K; Karlsson M; Gabrielsson S

Extracellulära vesiklers roll i immunförsvaret – Forskargrupp Susanne Gabrielsson

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