Forskargrupp Liv Eidsmo

Publikationer

Alla gruppmedlemmars publikationer

• Meeting abstract: BRITISH JOURNAL OF DERMATOLOGY. 2024;190(6):904-914

  Initial steps towards developing a predictive algorithm of disease progression for hidradenitis suppurativa (HS): results from a Cox proportional hazard regression analysis on disease progression among a cohort of 335 Danish patients with HS.

  Kjærsgaard Andersen R; Pedersen O; Eidsmo L; Jemec G; Saunte D
• Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54(1):e2350658

  The cellular microenvironment regulates CX3CR1 expression on CD8+ T cells and the maintenance of CX3CR1+ CD8+ T cells.

  Pokharel J; Shryki I; Zwijnenburg AJ; Sandu I; Krumm L; Bekiari C; Avramov V; Heinbäck R; Lysell J; Eidsmo L; Harris HE; Gerlach C
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;99(1):e13326

  Method for high-plex analysis of immune cells in human skin using the GeoMx system.

  Ignatov B; Sortebech D; Emmanuel T; Zhuravleva E; Eidsmo L
• Article: CLINICAL AND EXPERIMENTAL DERMATOLOGY. 2023;:llad329

  Investigation of plaque psoriasis relapse after secukinumab withdrawal in patients from two Phase 3 studies.

  Lebwohl M; Iversen L; Eidsmo L; Krueger JG; Suárez-Fariñas M; Tomalin L; Kolbinger F; You R; Milutinovic M
• Article: IMMUNITY. 2023;56(8):1955-1974.e10

  Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation.

  Zwijnenburg AJ; Pokharel J; Varnaitė R; Zheng W; Hoffer E; Shryki I; Comet NR; Ehrström M; Gredmark-Russ S; Eidsmo L; Gerlach C
• Article: IMMUNITY. 2023;56(6):1285-1302.e7

  Human skin-resident CD8+ T cells require RUNX2 and RUNX3 for induction of cytotoxicity and expression of the integrin CD49a.

  Zitti B; Hoffer E; Zheng W; Pandey RV; Schlums H; Perinetti Casoni G; Fusi I; Nguyen L; Kärner J; Kokkinou E; Carrasco A; Gahm J; Ehrström M; Happaniemi S; Keita ÅV; Hedin CRH; Mjösberg J; Eidsmo L; Bryceson YT
• Article: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2023;37(5):1004-1016

  Secukinumab demonstrates superiority over narrow-band ultraviolet B phototherapy in new-onset moderate to severe plaque psoriasis patients: Week 52 results from the STEPIn study.

  Iversen L; Conrad C; Eidsmo L; Costanzo A; Narbutt J; Pinter A; Kingo K; Rivera Diaz R; Kolbinger F; Nanna M; Frueh JA; Jagiello P
• Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1168684

  Skin infiltrating NK cells in cutaneous T-cell lymphoma are increased in number and display phenotypic alterations partially driven by the tumor.

  Scheffschick A; Nenonen J; Xiang M; Winther AH; Ehrström M; Wahren-Herlenius M; Eidsmo L; Brauner H
• Letter: ALLERGY. 2022;77(12):3680-3683

  T cells in resolved allergic contact dermatitis steer tissue inflammation and MMP-12-driven tissue modulation.

  Gallais Sérézal I; Tajpara P; Schonfeldt T; Ignatov B; Sortebech D; Hoffer E; Zhang T; Rooijackers E; Ehrström M; Nylén S; Matura M; Melican K; Eidsmo L
• Editorial comment: NEW ENGLAND JOURNAL OF MEDICINE. 2022;387(16):1515-1516

  New Hope for Patients with Vitiligo.

  Eidsmo L
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2022;142(3 Pt A):705-716

  Single-Cell Analysis Reveals Major Histocompatibility Complex II‒Expressing Keratinocytes in Pressure Ulcers with Worse Healing Outcomes.

  Li D; Cheng S; Pei Y; Sommar P; Kärner J; Herter EK; Toma MA; Zhang L; Pham K; Cheung YT; Liu Z; Chen X; Eidsmo L; Deng Q; Xu Landén N
• Article: MUCOSAL IMMUNOLOGY. 2022;15(2):257-267

  Intestinal helminth infection transforms the CD4+ T cell composition of the skin.

  Classon CH; Li M; Clavero AL; Ma J; Feng X; Tibbitt CA; Stark JM; Cardoso R; Ringqvist E; Boon L; Villablanca EJ; Rothfuchs AG; Eidsmo L; Coquet JM; Nylén S
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2022;142(2):333-342.e6

  IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation.

  Padhi A; Srivastava A; Ramesh A; Ehrström M; Simon M; Sonkoly E; Eidsmo L; Bergman P; Lysell J
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(51):e2100687118

  A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen.

  Landegren N; Ishii N; Aranda-Guillén M; Gunnarsson HI; Sardh F; Hallgren Å; Ståhle M; Hagforsen E; Bradley M; Edqvist P-HD; Pontén F; Mäkitie O; Eidsmo L; Norlén L; Achour A; Dahlbom I; Korponay-Szabó I; Agardh D; Alimohammadi M; Eriksson D; Hashimoto T; Kämpe O
• Article: ADVANCED MATERIALS TECHNOLOGIES. 2021;6(7):2001307

  Vancomycin-Loaded Microneedle Arrays against Methicillin-Resistant Staphylococcus Aureus Skin Infections.

  Ziesmer J; Tajpara P; Hempel N-J; Ehrström M; Melican K; Eidsmo L; Sotiriou GA
• Article: JAMA DERMATOLOGY. 2021;157(6):1-8

  Long-term Outcomes and Prognosis in New-Onset Psoriasis.

  Svedbom A; Mallbris L; Larsson P; Nikamo P; Wolk K; Kjellman P; Sonkoly E; Eidsmo L; Lindqvist U; Ståhle M
• Article: COMMUNICATIONS BIOLOGY. 2021;4(1):13

  Skin T cells maintain their diversity and functionality in the elderly.

  Koguchi-Yoshioka H; Hoffer E; Cheuk S; Matsumura Y; Vo S; Kjellman P; Grema L; Ishitsuka Y; Nakamura Y; Okiyama N; Fujisawa Y; Fujimoto M; Eidsmo L; Clark RA; Watanabe R
• Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2020;92(5):e12953

  Cellular scars and local crosstalk in relapsing psoriasis: an example of a skin sticking disease.

  Gallais Sérézal I; Cheuk S; Martini E; Eidsmo L
• Article: CELL REPORTS. 2019;29(5):1074-1081.e5

  Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization.

  Schulz A; Jiang L; de Vor L; Ehrström M; Wermeling F; Eidsmo L; Melican K
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(4):1444-1454

  A skewed pool of resident T cells triggers psoriasis-associated tissue responses in never-lesional skin from patients with psoriasis.

  Gallais Sérézal I; Hoffer E; Ignatov B; Martini E; Zitti B; Ehrström M; Eidsmo L
• Article: PARASITE IMMUNOLOGY. 2019;41(4):e12618

  Intestinal nematode infection exacerbates experimental visceral leishmaniasis.

  Classon C; Feng X; Eidsmo L; Nylén S
• Article: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2018;32(11):1930-1939

  Secukinumab treatment in new-onset psoriasis: aiming to understand the potential for disease modification - rationale and design of the randomized, multicenter STEPIn study.

  Iversen L; Eidsmo L; Austad J; de Rie M; Osmancevic A; Skov L; Talme T; Bachmann I; van de Kerkhof P; Stahle M; Banerjee R; Oliver J; Fasth AER; Frueh J
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018;138(8):1754-1763

  Resident T Cells in Resolved Psoriasis Steer Tissue Responses that Stratify Clinical Outcome.

  Gallais Sérézal I; Classon C; Cheuk S; Barrientos-Somarribas M; Wadman E; Martini E; Chang D; Xu Landén N; Ehrström M; Nylén S; Eidsmo L
• Article: JOURNAL OF INFECTIOUS DISEASES. 2018;218(3):453-465

  Human Immunodeficiency Virus-Infected Women Have High Numbers of CD103-CD8+ T Cells Residing Close to the Basal Membrane of the Ectocervical Epithelium.

  Gibbs A; Buggert M; Edfeldt G; Ranefall P; Introini A; Cheuk S; Martini E; Eidsmo L; Ball TB; Kimani J; Kaul R; Karlsson AC; Wählby C; Broliden K; Tjernlund A
• Editorial comment: TRENDS IN IMMUNOLOGY. 2018;39(3):170-172

  Heavy Water Shedding Light on Antigen-Specific T Cell Responses.

  Eidsmo L; Gerlach C
• Review: FRONTIERS IN IMMUNOLOGY. 2018;9:300

  Human Langerhans Cells with Pro-inflammatory Features Relocate within Psoriasis Lesions.

  Eidsmo L; Martini E
• Editorial comment: IMMUNITY. 2017;47(6):1012-1014

  The Skinny on Fat Trm Cells.

  Cheuk S; Eidsmo L
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(12):2630-2638

  MicroRNA-132 with Therapeutic Potential in Chronic Wounds.

  Li X; Li D; Wang A; Chu T; Lohcharoenkal W; Zheng X; Grünler J; Narayanan S; Eliasson S; Herter EK; Wang Y; Ma Y; Ehrström M; Eidsmo L; Kasper M; Pivarcsi A; Sonkoly E; Catrina S-B; Ståhle M; Xu Landén N
• Letter: EXPERIMENTAL DERMATOLOGY. 2017;26(9):824-827

  Granzyme A potentiates chemokine production in IL-17-stimulated keratinocytes.

  Cheuk S; Martini E; Bergh K; Chang D; Rethi B; Ståhle M; Eidsmo L
• Letter: EXPERIMENTAL DERMATOLOGY. 2017;26(5):444-446

  IL-22 binding protein regulates murine skin inflammation.

  Lindahl H; Martini E; Brauner S; Nikamo P; Gallais Serezal I; Guerreiro-Cacais AO; Jagodic M; Eidsmo L; Ståhle M; Olsson T
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(4):865-873

  Dynamic Changes in Resident and Infiltrating Epidermal Dendritic Cells in Active and Resolved Psoriasis.

  Martini E; Wikén M; Cheuk S; Gallais Sérézal I; Baharom F; Ståhle M; Smed-Sörensen A; Eidsmo L
• Article: SCIENTIFIC REPORTS. 2017;7:43989

  Immunogenicity is preferentially induced in sparse dendritic cell cultures.

  Nasi A; Bollampalli VP; Sun M; Chen Y; Amu S; Nylén S; Eidsmo L; Rothfuchs AG; Réthi B
• Article: IMMUNITY. 2017;46(2):287-300

  CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin.

  Cheuk S; Schlums H; Gallais Sérézal I; Martini E; Chiang SC; Marquardt N; Gibbs A; Detlofsson E; Introini A; Forkel M; Höög C; Tjernlund A; Michaëlsson J; Folkersen L; Mjösberg J; Blomqvist L; Ehrström M; Ståhle M; Bryceson YT; Eidsmo L
• Article: JOURNAL OF IMMUNOLOGY. 2016;197(8):3069-3075

  Fetal CD103+ IL-17-Producing Group 3 Innate Lymphoid Cells Represent the Dominant Lymphocyte Subset in Human Amniotic Fluid.

  Marquardt N; Ivarsson MA; Sundström E; Åkesson E; Martini E; Eidsmo L; Mjösberg J; Friberg D; Kublickas M; Ek S; Tegerstedt G; Seiger Å; Westgren M; Michaëlsson J
• Article: NATURE COMMUNICATIONS. 2016;7:12175

  Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells.

  Baptista MAP; Keszei M; Oliveira M; Sunahara KKS; Andersson J; Dahlberg CIM; Worth AJ; Liedén A; Kuo I-C; Wallin RPA; Snapper SB; Eidsmo L; Scheynius A; Karlsson MCI; Bouma G; Burns SO; Forsell MNE; Thrasher AJ; Nylén S; Westerberg LS
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(9):2351-2360

  Composition of innate lymphoid cell subsets in the human skin: enrichment of NCR(+) ILC3 in lesional skin and blood of psoriasis patients.

  Teunissen MBM; Munneke JM; Bernink JH; Spuls PI; Res PCM; Te Velde A; Cheuk S; Brouwer MWD; Menting SP; Eidsmo L; Spits H; Hazenberg MD; Mjösberg J
• Review: CLINICAL AND EXPERIMENTAL ALLERGY. 2014;44(8):1033-1043

  Update on innate lymphoid cells in atopic and non-atopic inflammation in the airways and skin.

  Mjösberg J; Eidsmo L
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(6):1535-1541

  Genetic variants of the IL22 promoter associate to onset of psoriasis before puberty and increased IL-22 production in T cells.

  Nikamo P; Cheuk S; Lysell J; Enerbäck C; Bergh K; Xu Landén N; Eidsmo L; Ståhle M
• Article: JOURNAL OF IMMUNOLOGY. 2014;192(7):3111-3120

  Epidermal Th22 and Tc17 cells form a localized disease memory in clinically healed psoriasis.

  Cheuk S; Wikén M; Blomqvist L; Nylén S; Talme T; Ståhle M; Eidsmo L
• Review: PARASITE IMMUNOLOGY. 2012;34(12):551-561

  Tissue damage and immunity in cutaneous leishmaniasis.

  Nylén S; Eidsmo L
• Article: JOURNAL OF PATHOLOGY. 2012;226(5):806-813

  Reactive murine lymph nodes uniquely permit parenchymal access for T cells that enter via the afferent lymphatics.

  Eidsmo L; Stock AT; Heath WR; Bedoui S; Carbone FR
• Review: FRONTIERS IN IMMUNOLOGY. 2012;3:163

  FasL and TRAIL signaling in the skin during cutaneous leishmaniasis - implications for tissue immunopathology and infectious control.

  Rethi B; Eidsmo L
• Article: PARASITOLOGY. 2011;138(14):1898-1909

  The interplay between Leishmania promastigotes and human Natural Killer cells in vitro leads to direct lysis of Leishmania by NK cells and modulation of NK cell activity by Leishmania promastigotes.

  Lieke T; Nylén S; Eidsmo L; Schmetz C; Berg L; Akuffo H
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2011;131(7):1521-1529

  MiR-125b, a microRNA downregulated in psoriasis, modulates keratinocyte proliferation by targeting FGFR2.

  Xu N; Brodin P; Wei T; Meisgen F; Eidsmo L; Nagy N; Kemeny L; Ståhle M; Sonkoly E; Pivarcsi A
• Article: PLOS NEGLECTED TROPICAL DISEASES. 2010;4(10):e844

  Systemic FasL and TRAIL neutralisation reduce leishmaniasis induced skin ulceration.

  Tasew G; Nylén S; Lieke T; Lemu B; Meless H; Ruffin N; Wolday D; Asseffa A; Yagita H; Britton S; Akuffo H; Chiodi F; Eidsmo L
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2010;126(3):581-9.e1-20-U306

  MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4.

  Sonkoly E; Janson P; Majuri M-L; Savinko T; Fyhrquist N; Eidsmo L; Xu N; Meisgen F; Wei T; Bradley M; Stenvang J; Kauppinen S; Alenius H; Lauerma A; Homey B; Winqvist O; Ståhle M; Pivarcsi A
• Article: GLOBAL HEALTH ACTION. 2009;2:2046

  Low-cost liquid medium for in vitro cultivation of Leishmania parasites in low-income countries.

  Tasew G; Kebede A; Wolday D; Gadisa E; Britton S; Eidsmo L; Akuffo H
• Article: JOURNAL OF IMMUNOLOGY. 2009;182(12):7587-7594

  The C-type lectin Clec12A present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses.

  Lahoud MH; Proietto AI; Ahmet F; Kitsoulis S; Eidsmo L; Wu L; Sathe P; Pietersz S; Chang H-W; Walker ID; Maraskovsky E; Braley H; Lew AM; Wright MD; Heath WR; Shortman K; Caminschi I
• Article: NATURE IMMUNOLOGY. 2009;10(5):488-495

  Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells.

  Bedoui S; Whitney PG; Waithman J; Eidsmo L; Wakim L; Caminschi I; Allan RS; Wojtasiak M; Shortman K; Carbone FR; Brooks AG; Heath WR
• Article: NATURE IMMUNOLOGY. 2009;10(5):524-530

  Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus.

  Gebhardt T; Wakim LM; Eidsmo L; Reading PC; Heath WR; Carbone FR
• Article: JOURNAL OF IMMUNOLOGY. 2009;182(5):3165-3172

  Differential migration of epidermal and dermal dendritic cells during skin infection.

  Eidsmo L; Allan R; Caminschi I; van Rooijen N; Heath WR; Carbone FR
• Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;153(2):221-230

  Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation.

  Lieke T; Nylén S; Eidsmo L; McMaster WR; Mohammadi AM; Khamesipour A; Berg L; Akuffo H
• Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2007;204(4):805-817

  Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis.

  Nylén S; Maurya R; Eidsmo L; Manandhar KD; Sundar S; Sacks D
• Article: JOURNAL OF IMMUNOLOGY. 2007;178(8):5340-5350

  Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection.

  Fluur C; De Milito A; Fry TJ; Vivar N; Eidsmo L; Atlas A; Federici C; Matarrese P; Logozzi M; Rajnavölgyi E; Mackall CL; Fais S; Chiodi F; Rethi B
• Article: AMERICAN JOURNAL OF PATHOLOGY. 2007;170(1):227-239

  FasL and TRAIL induce epidermal apoptosis and skin ulceration upon exposure to Leishmania major.

  Eidsmo L; Fluur C; Rethi B; Eriksson Ygberg S; Ruffin N; De Milito A; Akuffo H; Chiodi F
• Article: VACCINE. 2006;24(47-48):6944-6954

  Surrogate markers of immunity to Leishmania major in leishmanin skin test negative individuals from an endemic area re-visited.

  Nylén S; Khamesipour A; Mohammadi A; Jafari-Shakib R; Eidsmo L; Noazin S; Modabber F; Akuffo H
• Article: AMERICAN JOURNAL OF PATHOLOGY. 2005;166(4):1099-1108

  The contribution of the Fas/FasL apoptotic pathway in ulcer formation during Leishmania major-induced cutaneous Leishmaniasis.

  Eidsmo L; Nylen S; Khamesipour A; Hedblad M-A; Chiodi F; Akuffo H
• Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2002;130(2):307-313

  Alteration of Fas and Fas ligand expression during human visceral leishmaniasis.

  Eidsmo L; Wolday D; Berhe N; Sabri F; Satti I; El Hassan AM; Sundar S; Chiodi F; Akuffo H
• Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;117(3):529-534

  Natural killer cells in cross-regulation of IL-12 by IL-10 in Leishmania antigen-stimulated blood donor cells.

  Akuffo H; Alexis A; Eidsmo L; Saed A; Nylén S; Maasho K
• Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 1995;52(2):181-186

  Steroid 21-hydroxylase in the kidney: demonstration of levels of messenger RNA which correlate with the level of activity.

  Lajic S; Eidsmo L; Holst M
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Medarbetare och kontakt

Gruppledare

• 

  Liv Eidsmo

  Professor/Överläkare | Docent

  E-postadress liv.eidsmo@ki.se

Alla medlemmar i gruppen

• 

  Liv Eidsmo

  Professor/Överläkare | Docent

  E-postadress liv.eidsmo@ki.se
• Elena Hoffer

  Anknuten till Forskning

  E-postadress elena.hoffer@ki.se
• Wenning Zheng

  Postdoktorala Studier

  E-postadress wenning.zheng@ki.se
• Ekaterina Zhuravleva

  Anknuten till Forskning

  E-postadress ekaterina.zhuravleva@ki.se