Små RNA i cancerutveckling – Weng-Onn Luis team

Publikationer

Utvalda publikationer

• Review: DRUG RESISTANCE UPDATES. 2026;85:101355

  The hallmarks of oncogenic signaling: From pathways to resistance in cancer therapy

  Tufail M; Gong K; Ijaz B; Patel H; Lui W-O; Wang X; Li J
• Article: ONCOGENE. 2025;44(47):4615-4625

  High-resolution spatial transcriptomics uncover epidermal-dermal divergences in Merkel cell carcinoma: spatial context reshapes the gene expression landscape

  Lei KC; Srinivas N; Chandra M; Serobyan V; Ugurel S; Hoffmann D; Kervarrec T; Lui W-O; Becker JC
• Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2025;13(9):e012224

  Tertiary lymphoid structures in Merkel cell carcinoma facilitate naïve and central memory T-cell infiltration linked to immunotherapy response

  Srinivas N; Spassova I; Lei KC; Gao J; Pino MJ; Giglio G; Kitanovski S; Dalkoohi M; Livingstone E; Leiter U; Mohr P; Gambichler T; Stoffels I; Ugurel S; Cheung PF-Y; Engblom C; Lui W-O; Becker JC
• Article: NATURE COMMUNICATIONS. 2025;16(1):6610

  Targeting CD37 promotes macrophage-dependent phagocytosis of multiple cancer cell types and facilitates tumor clearance in mice

  Gao X; Zhang J; Zhang H; Liu X; Zeng B; Wang H; Zhang H; Lui W-O; Hui X; Miao H; Li J
• Article: AUTOPHAGY. 2025;21(7):1523-1543

  Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma

  Shi H; Yang Y; Gao J; Kumar S; Xie H; Chen Z; Lyu J; Sihto H; Koljonen V; Vega-Rubin-de-Celis S; Vukojevic V; Farnebo F; Bjornhagen V; Hoog A; Juhlin CC; Lee L; Wickstroem M; Becker JC; Johnsen JI; Larsson C; Lui W-O
• Other: LANCET ONCOLOGY. 2025;26(8):994-995

  Carcinogenicity of hepatitis D virus, human cytomegalovirus, and Merkel cell polyomavirus

  Karagas MR; Kaldor J; Michaelis M; Muchengeti MM; Alfaiate D; Argirion I; Chen X; Cunha C; Hantz S; Koljonen V; Laude HC; Lui W-O; Nevels MM; O'Brien TR; Scheurer ME; Touze A; Wiemels JL; Benbrahim-Tallaa L; de Conti A; Facchin C; Madia F; Pasqual E; Wedekind R; Aguilera-Buenosvinos I; Clifford G; Deng X; Dongoran RA; Ezzemni S; Huang Y; Suonio E; Zhai Y; Mattock H; Schubauer-Berigan MK; Kunzmann A

Alla gruppmedlemmars publikationer

• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2026;:S0022-202X(26)02812-5

  Differential c-KIT trafficking in Merkel cell carcinoma: Signaling and prognostic implications.

  Wang X; Sihto H; Yang Y; Larsson C; Shi H; Lui W-O
• Review: JOURNAL OF INTERNAL MEDICINE. 2026;299(5):538-569

  Perioperative immune checkpoint inhibitor therapy across tumors: Insights and shared lessons from a rapidly evolving field

  Bjorkstrom K; Matikas A; Svedman FC; Bjorgvinsson E; Zupancic M; Villabona L; Eriksson H; Skribek M; Fernebro J; Lindskog M; Frodin J-E; Ullen A; Ekman S; Helgadottir H
• Review: DRUG RESISTANCE UPDATES. 2026;85:101355

  The hallmarks of oncogenic signaling: From pathways to resistance in cancer therapy

  Tufail M; Gong K; Ijaz B; Patel H; Lui W-O; Wang X; Li J
• Article: ONCOGENE. 2025;44(47):4615-4625

  High-resolution spatial transcriptomics uncover epidermal-dermal divergences in Merkel cell carcinoma: spatial context reshapes the gene expression landscape

  Lei KC; Srinivas N; Chandra M; Serobyan V; Ugurel S; Hoffmann D; Kervarrec T; Lui W-O; Becker JC
• Article: MOLECULAR CARCINOGENESIS. 2025;64(11):1899-1912

  miR-150-5p Regulates Merkel Cell Carcinoma Progression by Targeting FTO That Stabilizes CTNNB1 via m6A Modification

  Zheng B; Li M; Gao Z; Yang Y; Guo K; Gao H; Zhao Y; Lui W-O; Xie H
• Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2025;13(9):e012224

  Tertiary lymphoid structures in Merkel cell carcinoma facilitate naïve and central memory T-cell infiltration linked to immunotherapy response

  Srinivas N; Spassova I; Lei KC; Gao J; Pino MJ; Giglio G; Kitanovski S; Dalkoohi M; Livingstone E; Leiter U; Mohr P; Gambichler T; Stoffels I; Ugurel S; Cheung PF-Y; Engblom C; Lui W-O; Becker JC
• Doctoral thesis: 2025

  Uncovering metastasis biomarkers and molecular mechanisms in Merkel cell carcinoma

  Yang Y
• Corrigendum: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2025;320(Pt 1):146595

  Molecular mechanism of long chain non coding RNA LINC00511 influencing breast cancer stem cells: Mechanism of VEGFR1 protein (Vol 302, 140437, 2025)

  Li J; Lu J; Liu G; Li J; Chen J; Wang X; Lui W-O; Lu G
• Article: NATURE COMMUNICATIONS. 2025;16(1):6610

  Targeting CD37 promotes macrophage-dependent phagocytosis of multiple cancer cell types and facilitates tumor clearance in mice

  Gao X; Zhang J; Zhang H; Liu X; Zeng B; Wang H; Zhang H; Lui W-O; Hui X; Miao H; Li J
• Article: AUTOPHAGY. 2025;21(7):1523-1543

  Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma

  Shi H; Yang Y; Gao J; Kumar S; Xie H; Chen Z; Lyu J; Sihto H; Koljonen V; Vega-Rubin-de-Celis S; Vukojevic V; Farnebo F; Bjornhagen V; Hoog A; Juhlin CC; Lee L; Wickstroem M; Becker JC; Johnsen JI; Larsson C; Lui W-O
• Other: LANCET ONCOLOGY. 2025;26(8):994-995

  Carcinogenicity of hepatitis D virus, human cytomegalovirus, and Merkel cell polyomavirus

  Karagas MR; Kaldor J; Michaelis M; Muchengeti MM; Alfaiate D; Argirion I; Chen X; Cunha C; Hantz S; Koljonen V; Laude HC; Lui W-O; Nevels MM; O'Brien TR; Scheurer ME; Touze A; Wiemels JL; Benbrahim-Tallaa L; de Conti A; Facchin C; Madia F; Pasqual E; Wedekind R; Aguilera-Buenosvinos I; Clifford G; Deng X; Dongoran RA; Ezzemni S; Huang Y; Suonio E; Zhai Y; Mattock H; Schubauer-Berigan MK; Kunzmann A
• Article: JID INNOVATIONS. 2025;5(3):100355

  IGF2BP3 As a Prognostic Biomarker and Regulator of Metastasis in Merkel Cell Carcinoma

  Yang Y; Gao J; Shi H; Sihto H; Kilpinen S; Vilcot F; Janska L; Jeschonneck J; Cvetanovic T; Hoog A; Siarov J; Paoli J; Juhlin CC; Villabona L; Larsson C; Lui W-O
• Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2025;110(3):693-705

  BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer

  Xu Y; Gao J; Wang N; Zedenius J; Nilsson I-L; Lui W-O; Xu D; Juhlin CC; Larsson C; Mu N
• Article: LIFE SCIENCE ALLIANCE. 2025;8(1):e202403053

  Direct visualization of emergent metastatic features within an ex vivo model of the tumor microenvironment.

  Anandi L; Garcia J; Ros M; Janská L; Liu J; Carmona-Fontaine C
• Article: AMERICAN JOURNAL OF CLINICAL DERMATOLOGY. 2024;25(6):987-996

  Pembrolizumab for the First-Line Treatment of Recurrent Locally Advanced or Metastatic Merkel Cell Carcinoma: Results from the Single-Arm, Open-Label, Phase III KEYNOTE-913 Study

  Mortier L; Villabona L; Lawrence B; Arance A; Butler MO; Beylot-Barry M; Saiag P; Samimi M; Ascierto PA; Spada F; De Pontville M; Maio M; Berrocal A; Espinosa E; Capdevila J; Levin M; Das D; Krepler C; Grebennik D; Chiarion-Sileni V
• Article: PLOS BIOLOGY. 2024;22(7):e3002698

  Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects.

  Plavskin Y; de Biase MS; Ziv N; Janská L; Zhu YO; Hall DW; Schwarz RF; Tranchina D; Siegal ML
• Article: CELLS. 2023;12(13):1682

  Modulation of E-Cadherin Function through the AmotL2 Isoforms Promotes Ameboid Cell Invasion

  Subramani A; Cui W; Zhang Y; Friman T; Zhao Z; Huang W; Fonseca P; Lui W-O; Narayanan V; Bobrowska J; Lekka M; Yan J; Conway DEE; Holmgren L
• Article: DEVELOPMENTAL CELL. 2023;58(6):450-460.e6

  A small noncoding RNA links ribosome recovery and translation control to dedifferentiation during salamander limb regeneration

  Subramanian E; Elewa A; Brito G; Kumar A; Segerstolpe A; Karampelias C; Bjorklund A; Sandberg R; Echeverri K; Lui W-O; Andersson O; Simon A
• Article: GLAND SURGERY. 2023;12(2):197-207

  Bioinformatics combined with clinical data to analyze clinical characteristics and prognosis in patients with HER2 low expression breast cancer.

  Chen Y; Ma Y; Li Y; Yu Y; Lu B; Liao L; Li F; Wen Z; Jiang W; Guo P; Fang D; Lu G
• Corrigendum: ONCOGENE. 2023;42(9):709

  Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3s (vol 33, pg 4407, 2014)

  Bersani C; Xu L-D; Vilborg A; Lui W-O; Wiman KG
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Finansiering

Medarbetare och kontakt

Gruppledare

• 

  Weng-Onn Lui

  Professor

  E-postadress weng-onn.lui@ki.se

Alla medarbetare i gruppen

• Hannah Björn Andtback

  Doktorand

  E-postadress hannah.bjorn.andtback@ki.se
• Zana Brilej

  Doktorand

  E-postadress zana.brilej@ki.se
• Jiwei Gao

  Anknuten till Forskning

  E-postadress jiwei.gao@ki.se
• Libuse Janská

  Doktorand

  E-postadress libuse.janska@ki.se
• Hao Shi

  Anknuten till Forskning

  E-postadress hao.shi@ki.se
• Lisa Elena Esther Villabona

  Adjungerad Adjunkt

  E-postadress lisa.villabona@ki.se
• Xiaohao Wang

  Doktorand

  E-postadress xiaohao.wang@ki.se
• 

  Yajie Yang

  Doktorand

  E-postadress yajie.yang@ki.se
• 

  Zhenhua Zhang

  Anknuten till Forskning

  E-postadress zhenhua.zhang@ki.se

Andra personer med koppling till gruppen

• Villabona, Lisa