Ulrika Marklunds grupp

Marklunds lab forskar kring nervcellerna i enteriska nervsystemet (ENS). Genom att ta reda på vilka olika typer av nervceller som existerar, vilken funktion var och en har, samt hur de bildas under fosterutvecklingen hoppas gruppen kunna bidra till att förbättra diagnostik och terapi för mag- och tarmsjukdomar som vi idag har otillräcklig kunskap om. Tekniker som labbet använder inkluderar transkriptomanalys och virus-medierad genmanipulation i musmodellen.

Part of the:

Institutionen för medicinsk biokemi och biofysik

Publications
Staff and contact

Publications

Selected publications

Journal article: NATURE NEUROSCIENCE. 2025;28(6):1146-1159
The transcriptomes, connections and development of submucosal neuron classes in the mouse small intestine
Li W; Morarach K; Liu Z; Banerjee S; Chen Y; Harb AL; Kosareff JM; Hall CR; Lopez-Redondo F; Jalalvand E; Mohamed SH; Mikhailova A; Linden DR; Marklund U
Editorial: NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY. 2022;19(2):85-86
Diversity, development and immunoregulation of enteric neurons
Marklund U
Article: NATURE NEUROSCIENCE. 2021;24(1):34-46
Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing
Morarach K; Mikhailova A; Knoflach V; Memic F; Kumar R; Li W; Ernfors P; Marklund U
Article: CELL. 2018;174(4):999-1014.e22
Molecular Architecture of the Mouse Nervous System
Zeisel A; Hochgerner H; Lonnerberg P; Johnsson A; Memic F; van der Zwan J; Haring M; Braun E; Borm LE; La Manno G; Codeluppi S; Furlan A; Lee K; Skene N; Harris KD; Hjerling-Leffler J; Arenas E; Ernfors P; Marklund U; Linnarsson S
Article: GASTROENTEROLOGY. 2018;154(3):624-636
Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System
Memic F; Knoflach V; Morarach K; Sadler R; Laranjeira C; Hjerling-Leffler J; Sundstrom E; Pachnis V; Marklund U
Article: JOURNAL OF NEUROSCIENCE. 2016;36(15):4339-4350
Ascl1 Is Required for the Development of Specific Neuronal Subtypes in the Enteric Nervous System
Memic F; Knoflach V; Sadler R; Tegerstedt G; Sundstrom E; Guillemot F; Pachnis V; Marklund U
Article: DEVELOPMENT. 2010;137(3):437-445
Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression
Marklund U; Hansson EM; Sundstrom E; de Angelis MH; Przemeck GKH; Lendahl U; Muhr J; Ericson J
Article: CELL. 2006;124(2):393-405
Identification of intrinsic determinants of midbrain dopamine neurons
Andersson E; Tryggvason U; Deng QL; Friling S; Alekseenko Z; Robert B; Perlmann T; Ericson J

Staff and contact

Group leader

Ulrika Marklund
Senior Forskare | Docent
Telephone +46852483519
E-mail ulrika.marklund@ki.se

All members of the group

Sanghita Banerjee
Anknuten till Forskning
E-mail sanghita.banerjee@ki.se
Yanan Chen
Postdoktor
E-mail yanan.chen@ki.se
Manuel Pinto
Doktorand
E-mail manuel.pinto@ki.se
Elham Jalalvand
Forskningssamordnare
Telephone +46852487166
E-mail elham.jalalvand@ki.se
Wei Li
Postdoktor
E-mail wei.li@ki.se
Ziwei Liu
Doktorand-L
E-mail ziwei.liu@ki.se
Khomgrit Morarach
Anknuten till Forskning
E-mail khomgrit.morarach@ki.se
Krishnanand Padmanabhan
Postdoktor
E-mail krishnanand.padmanabhan@ki.se
Siddharth Paliwal
Anknuten till Forskning
E-mail siddharth.paliwal@ki.se
Lauren Samantha Phipps
Postdoktor
E-mail lauren.phipps@ki.se
Chiara Tremolanti
Anknuten till Forskning
E-mail chiara.tremolanti@ki.se