Neurobiologi vid fetma – Alessandro Furlans grupp

In the Furlan lab we use transcriptomics, circuit-tracing methods and functional neural manipulation (i.e. opto- and chemo genetics) to identify and characterize the central and peripheral circuits through which the brain and the organs “talk”. Our goal is to understand how the brain and the body work together to regulate critical physiological processes, with a focus on weight regulation and obesity (see schematic).

Publikationer

Utvalda publikationer

Journal article: NATURE NEUROSCIENCE. 2022;25(11):1470-1480
Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis
Furlane A; Corona A; Boyle S; Sharma R; Rubino R; Habel J; Gablenze EC; Giovanniello J; Beyaz S; Janowitze T; Shea SD; Li B
Article: CELL. 2018;174(4):999-1014.e22
Molecular Architecture of the Mouse Nervous System
Zeisel A; Hochgerner H; Lonnerberg P; Johnsson A; Memic F; van der Zwan J; Haring M; Braun E; Borm LE; La Manno G; Codeluppi S; Furlan A; Lee K; Skene N; Harris KD; Hjerling-Leffler J; Arenas E; Ernfors P; Marklund U; Linnarsson S
Article: SCIENCE. 2017;357(6346):eaal3753
Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla
Furlan A; Dyachuk V; Kastriti ME; Calvo-Enrique L; Abdo H; Hadjab S; Chontorotzea T; Akkuratova N; Usoskin D; Kamenev D; Petersen J; Sunadome K; Memic F; Marklund U; Fried K; Topilko P; Lallemend F; Kharchenko PV; Ernfors P; Adameyko I
Article: NATURE NEUROSCIENCE. 2016;19(10):1331-1340
Visceral motor neuron diversity delineates a cellular basis for nipple- and pilo-erection muscle control
Furlan A; La Manno G; Lubke M; Haring M; Abdo H; Hochgerner H; Kupari J; Usoskin D; Airaksinen MS; Oliver G; Linnarsson S; Ernfors P
Article: NATURE NEUROSCIENCE. 2015;18(1):145-153
Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
Usoskin D; Furlan A; Islam S; Abdo H; Lonnerberg P; Lou D; Hjerling-Leffler J; Haeggstrom J; Kharchenko O; Kharchenko PV; Linnarsson S; Ernfors P
Article: SCIENCE. 2014;345(6192):82-87
Parasympathetic neurons originate from nerve-associated peripheral glial progenitors
Dyachuk V; Furlan A; Shahidi MK; Giovenco M; Kaukua N; Konstantinidou C; Pachnis V; Memic F; Marklund U; Mueller T; Birchmeier C; Fried K; Ernfors P; Adameyko I
Article: EMBO JOURNAL. 2013;32(11):1613-1625
The transcription factor Hmx1 and growth factor receptor activities control sympathetic neurons diversification
Furlan A; Lubke M; Adameyko I; Lallemend F; Ernfors P

Neurobiologi vid fetma – Alessandro Furlans grupp

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Neurobiologi vid fetma – Alessandro Furlans grupp

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