Neurobiologi vid stress och behandlingsreaktioner – Juan Pablo Lopez grupp

Article: CELL REPORTS. 2023;42(8):112874

Sex shapes cell-type-specific transcriptional signatures of stress exposure in the mouse hypothalamus.

Brivio E; Kos A; Ulivi AF; Karamihalev S; Ressle A; Stoffel R; Hirsch D; Stelzer G; Schmidt MV; Lopez JP; Chen A

Article: STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS. 2023;26(1):2186141

Increasing resolution in stress neurobiology: from single cells to complex group behaviors.

Miranda L; Bordes J; Gasperoni S; Lopez JP

Article: NEURON. 2022;110(14):2283-2298.e9

Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2.

Lopez JP; Lücken MD; Brivio E; Karamihalev S; Kos A; De Donno C; Benjamin A; Yang H; Dick ALW; Stoffel R; Flachskamm C; Ressle A; Roeh S; Huettl R-E; Parl A; Eggert C; Novak B; Yan Y; Yeoh K; Holzapfel M; Hauger B; Harbich D; Schmid B; Di Giaimo R; Turck CW; Schmidt MV; Deussing JM; Eder M; Dine J; Theis FJ; Chen A

Journal article: SCIENCE ADVANCES. 2021;7(5):eabe4497

Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation.

Lopez JP; Brivio E; Santambrogio A; De Donno C; Kos A; Peters M; Rost N; Czamara D; Brückl TM; Roeh S; Pöhlmann ML; Engelhardt C; Ressle A; Stoffel R; Tontsch A; Villamizar JM; Reincke M; Riester A; Sbiera S; Fassnacht M; Mayberg HS; Craighead WE; Dunlop BW; Nemeroff CB; Schmidt MV; Binder EB; Theis FJ; Beuschlein F; Andoniadou CL; Chen A

Journal article: GENES BRAIN AND BEHAVIOR. 2020;19(3):e12643

Sex differences: Transcriptional signatures of stress exposure in male and female brains.

Brivio E; Lopez JP; Chen A

Journal article: STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS. 2018;21(5):384-388

Preclinical stress research: where are we headed? An early career investigator's perspective.

Gururajan A; Kos A; Lopez JP

Journal article: CURRENT OPINION IN PSYCHIATRY. 2018;31(1):7-16

Major depression and its treatment: microRNAs as peripheral biomarkers of diagnosis and treatment response.

Lopez JP; Kos A; Turecki G

Journal article: NEUROPSYCHOPHARMACOLOGY. 2017;42(10):2043-2051

Co-Variation of Peripheral Levels of miR-1202 and Brain Activity and Connectivity During Antidepressant Treatment.

Lopez JP; Pereira F; Richard-Devantoy S; Berlim M; Chachamovich E; Fiori LM; Niola P; Turecki G; Jollant F

Letter: MOLECULAR PSYCHIATRY. 2017;22(9):1228-1229

Dysregulation of the glutamatergic receptors after antidepressant treatment in human neural progenitor cells.

Cruceanu C; Lopez JP; Tsai W-T; Turecki G

Journal article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2017;20(8):619-623

Investigation of miR-1202, miR-135a, and miR-16 in Major Depressive Disorder and Antidepressant Response.

Fiori LM; Lopez JP; Richard-Devantoy S; Berlim M; Chachamovich E; Jollant F; Foster J; Rotzinger S; Kennedy SH; Turecki G

Article: NATURE COMMUNICATIONS. 2017;8:15497

MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.

Lopez JP; Fiori LM; Cruceanu C; Lin R; Labonte B; Cates HM; Heller EA; Vialou V; Ku SM; Gerald C; Han M-H; Foster J; Frey BN; Soares CN; Müller DJ; Farzan F; Leri F; MacQueen GM; Feilotter H; Tyryshkin K; Evans KR; Giacobbe P; Blier P; Lam RW; Milev R; Parikh SV; Rotzinger S; Strother SC; Lewis CM; Aitchison KJ; Wittenberg GM; Mechawar N; Nestler EJ; Uher R; Kennedy SH; Turecki G

Journal article: BIOLOGICAL PSYCHIATRY. 2017;81(4):306-315

DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218.

Torres-Berrío A; Lopez JP; Bagot RC; Nouel D; Dal Bo G; Cuesta S; Zhu L; Manitt C; Eng C; Cooper HM; Storch K-F; Turecki G; Nestler EJ; Flores C

Article: BMC MEDICAL GENOMICS. 2015;8:35

Biomarker discovery: quantification of microRNAs and other small non-coding RNAs using next generation sequencing.

Lopez JP; Diallo A; Cruceanu C; Fiori LM; Laboissiere S; Guillet I; Fontaine J; Ragoussis J; Benes V; Turecki G; Ernst C

Article: NATURE MEDICINE. 2014;20(7):764-768

miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment.

Lopez JP; Lim R; Cruceanu C; Crapper L; Fasano C; Labonte B; Maussion G; Yang JP; Yerko V; Vigneault E; El Mestikawy S; Mechawar N; Pavlidis P; Turecki G

Journal article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2014;17(1):23-32

Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers.

Lopez JP; Fiori LM; Gross JA; Labonte B; Yerko V; Mechawar N; Turecki G

Journal article: MOLECULAR PSYCHIATRY. 2013;18(4):398-399

Epigenetic regulation of BDNF expression according to antidepressant response.

Lopez JP; Mamdani F; Labonte B; Beaulieu M-M; Yang JP; Berlim MT; Ernst C; Turecki G

Neurobiologi vid stress och behandlingsreaktioner – Juan Pablo Lopez grupp

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Neurobiologi vid stress och behandlingsreaktioner – Juan Pablo Lopez grupp

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