Nervceller och neurala nätverk – Ole Kiehns forskargrupp

Publikationer

Utvalda publikationer

• Journal article: NATURE NEUROSCIENCE. 2025;28(7):1473-1485

  A hypothalamus-brainstem circuit governs the prioritization of safety over essential needs

  Krauth N; Sach LK; Sitzia G; Clemmensen C; Kiehn O
• Article: NATURE NEUROSCIENCE. 2024;27(4):716-727

  Basal ganglia-spinal cord pathway that commands locomotor gait asymmetries in mice

  Cregg JM; Sidhu SK; Leiras R; Kiehn O
• Article: NATURE NEUROSCIENCE. 2023;26(9):1516-1528

  Pedunculopontine Chx10⁺ neurons control global motor arrest in mice

  Goni-Erro H; Selvan R; Leiras R; Kiehn O
• Article: NATURE COMMUNICATIONS. 2023;14(1):873

  Deconstructing the modular organization and real-time dynamics of mammalian spinal locomotor networks

  Hsu L-J; Bertho M; Kiehn O
• Article: NATURE COMMUNICATIONS. 2022;13(1):504

  Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism

  Masini D; Kiehn O
• Article: NATURE NEUROSCIENCE. 2020;23(6):730-740

  Brainstem neurons that command mammalian locomotor asymmetries

  Cregg JM; Leiras R; Montalant A; Wanken P; Wickersham IR; Kiehn O
• Article: SCIENCE TRANSLATIONAL MEDICINE. 2020;12(539):eaay0167

  Early delivery and prolonged treatment with nimodipine prevents the development of spasticity after spinal cord injury in mice

  Marcantoni M; Fuchs A; Low P; Bartsch D; Kiehn O; Bellardita C
• Article: NATURE. 2018;553(7689):455-460

  Midbrain circuits that set locomotor speed and gait selection

  Caggiano V; Leiras R; Goni-Erro H; Masini D; Bellardita C; Bouvier J; Caldeira V; Fisone G; Kiehn O
• Review: NATURE REVIEWS NEUROSCIENCE. 2016;17(4):224-238

  Decoding the organization of spinal circuits that control locomotion

  Kiehn O
• Article: CELL. 2015;163(5):1191-1203

  Descending Command Neurons in the Brainstem that Halt Locomotion

  Bouvier J; Caggiano V; Leiras R; Caldeira V; Bellardita C; Balueva K; Fuchs A; Kiehn O
• Article: NEURON. 2013;80(4):920-933

  Locomotor Rhythm Generation Linked to the Output of Spinal Shox2 Excitatory Interneurons

  Dougherty KJ; Zagoraiou L; Satoh D; Rozani I; Doobar S; Arber S; Jessell TM; Kiehn O
• Article: NATURE. 2013;500(7460):85-88

  Dual-mode operation of neuronal networks involved in left-right alternation

  Talpalar AE; Bouvier J; Borgius L; Fortin G; Pierani A; Kiehn O
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(28):11589-11594

  Optogenetic dissection reveals multiple rhythmogenic modules underlying locomotion

  Hagglund M; Dougherty KJ; Borgius L; Itohara S; Iwasato T; Kiehn O
• Article: NEURON. 2011;71(6):1071-1084

  Identification of Minimal Neuronal Networks Involved in Flexor-Extensor Alternation in the Mammalian Spinal Cord

  Talpalar AE; Endo T; Low P; Borgius L; Hagglund M; Dougherty KJ; Ryge J; Hnasko TS; Kiehn O
• Article: NATURE NEUROSCIENCE. 2010;13(2):246-252

  Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion

  Hagglund M; Borgius L; Dougherty KJ; Kiehn O

Alla gruppmedlemmars publikationer

• Article: JOURNAL OF NEUROSCIENCE. 2024;44(18):e1607232024

  Excitatory Spinal Lhx9-Derived Interneurons Modulate Locomotor Frequency in Mice

  Bertho M; Caldeira V; Hsu L-J; Loew P; Borgius L; Kiehn O
• Article: NATURE NEUROSCIENCE. 2024;27(4):716-727

  Basal ganglia-spinal cord pathway that commands locomotor gait asymmetries in mice

  Cregg JM; Sidhu SK; Leiras R; Kiehn O
• Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2024;59(6):1278-1295

  Dopamine and noradrenaline activate spinal astrocyte endfeet via D1-like receptors.

  Montalant A; Kiehn O; Perrier J-F
• Article: NATURE NEUROSCIENCE. 2023;26(9):1516-1528

  Pedunculopontine Chx10⁺ neurons control global motor arrest in mice

  Goni-Erro H; Selvan R; Leiras R; Kiehn O
• Article: NATURE COMMUNICATIONS. 2023;14(1):873

  Deconstructing the modular organization and real-time dynamics of mammalian spinal locomotor networks

  Hsu L-J; Bertho M; Kiehn O
• Review: ANNUAL REVIEW OF NEUROSCIENCE. 2022;45:63-85

  Brainstem Circuits for Locomotion

  Leiras R; Cregg JM; Kiehn O
• Article: BIOLOGICAL PSYCHIATRY. 2022;91(8):727-739

  Identification of Vulnerable Interneuron Subtypes in 15q13.3 Microdeletion Syndrome Using Single-Cell Transcriptomics.

  Malwade S; Gasthaus J; Bellardita C; Andelic M; Moric B; Korshunova I; Kiehn O; Vasistha NA; Khodosevich K
• Article: NATURE COMMUNICATIONS. 2022;13(1):504

  Targeted activation of midbrain neurons restores locomotor function in mouse models of parkinsonism

  Masini D; Kiehn O
• Article: NATURE COMMUNICATIONS. 2021;12(1):3251

  Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons

  Allodi I; Montanana-Rosell R; Selvan R; Low P; Kiehn O
• Article: JOURNAL OF NEUROSCIENCE. 2021;41(15):3432-3445

  Differential Contribution of V0 Interneurons to Execution of Rhythmic and Nonrhythmic Motor Behaviors

  Zelenin PV; Vemula MG; Lyalka VF; Kiehn O; Talpalar AE; Deliagina TG
• Article: NATURE COMMUNICATIONS. 2021;12(1):1026

  Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice

  Wu H; Petitpre C; Fontanet P; Sharma A; Bellardita C; Quadros RM; Jannig PR; Wang Y; Heimel JA; Cheung KKY; Wanderoy S; Xuan Y; Meletis K; Ruas J; Gurumurthy CB; Kiehn O; Hadjab S; Lallemend F
• Article: NATURE NEUROSCIENCE. 2020;23(12):1456-1468

  A community-based transcriptomics classification and nomenclature of neocortical cell types

  Yuste R; Hawrylycz M; Aalling N; Aguilar-Valles A; Arendt D; Arnedillo RA; Ascoli GA; Bielza C; Bokharaie V; Bergmann TB; Bystron I; Capogna M; Chang Y; Clemens A; de Kock CPJ; DeFelipe J; Dos Santos SE; Dunville K; Feldmeyer D; Fiath R; Fishell GJ; Foggetti A; Gao X; Ghaderi P; Goriounova NA; Guentuerkuen O; Hagihara K; Hall VJ; Helmstaedter M; Herculano S; Hilscher MM; Hirase H; Hjerling-Leffler J; Hodge R; Huang J; Huda R; Khodosevich K; Kiehn O; Koch H; Kuebler ES; Kuhnemund M; Larranaga P; Lelieveldt B; Louth EL; Lui JH; Mansvelder HD; Marin O; Martinez-Trujillo J; Moradi Chameh H; Nath A; Nedergaard M; Nemec P; Ofer N; Pfisterer UG; Pontes S; Redmond W; Rossier J; Sanes JR; Scheuermann R; Serrano-Saiz E; Steiger JF; Somogyi P; Tamas G; Tolias AS; Tosches MA; Garcia MT; Vieira HM; Wozny C; Wuttke TV; Yong L; Yuan J; Zeng H; Lein E
• Article: NATURE NEUROSCIENCE. 2020;23(6):730-740

  Brainstem neurons that command mammalian locomotor asymmetries

  Cregg JM; Leiras R; Montalant A; Wanken P; Wickersham IR; Kiehn O
• Article: SCIENCE TRANSLATIONAL MEDICINE. 2020;12(539):eaay0167

  Early delivery and prolonged treatment with nimodipine prevents the development of spasticity after spinal cord injury in mice

  Marcantoni M; Fuchs A; Low P; Bartsch D; Kiehn O; Bellardita C
• Article: DEVELOPMENT. 2019;146(20):dev181750

  Muscle-selective RUNX3 dependence of sensorimotor circuit development

  Wang Y; Wu H; Zelenin P; Fontanet P; Wanderoy S; Petitpre C; Comai G; Bellardita C; Xue-Franzen Y; Huettl R-E; Huber AB; Tajbakhsh S; Kiehn O; Ernfors P; Deliagina TG; Lallemend F; Hadjab S
• Article: STEM CELL REPORTS. 2019;12(6):1329-1341

  Modeling Motor Neuron Resilience in ALS Using Stem Cells

  Allodi I; Nijssen J; Benitez JA; Schweingruber C; Fuchs A; Bonvicini G; Cao M; Kiehn O; Hedlund E
• Article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(9):3757-3768

  Ca²⁺- binding protein NECAB2 facilitates inflammatory pain hypersensitivity

  Zhang M-D; Su J; Adori C; Cinquina V; Malenczyk K; Girach F; Peng C; Ernfors P; Low P; Borgius L; Kiehn O; Watanabe M; Uhlen M; Mitsios N; Mulder J; Harkany T; Hokfelt T
• Article: NATURE NEUROSCIENCE. 2018;21(6):869-880

  Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types

  Haring M; Zeisel A; Hochgerner H; Rinwa P; Jakobsson JET; Lonnerberg P; La Manno G; Sharma N; Borgius L; Kiehn O; Lagerstrom MC; Linnarsson S; Ernfors P
• Article: BIO-PROTOCOL. 2018;8(7):e2784

  Sacral Spinal Cord Transection and Isolated Sacral Cord Preparation to Study Chronic Spinal Cord Injury in Adult Mice

  Bellardita C; Marcantoni M; Low P; Kiehn O
• Article: NATURE. 2018;553(7689):455-460

  Midbrain circuits that set locomotor speed and gait selection

  Caggiano V; Leiras R; Goni-Erro H; Masini D; Bellardita C; Bouvier J; Caldeira V; Fisone G; Kiehn O
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Medarbetare och kontakt

Gruppledare

• 

  Ole Kiehn

  Professor

  Telefon +46852482903

  E-postadress ole.kiehn@ki.se