Översättning av mRNA i cancer – Ola Larssons forskargrupp

Publikationer

Utvalda publikationer

• Article: CELL REPORTS. 2022;40(3):111092

  Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR

  Krokowski D; Jobava R; Szkop KJ; Chen C-W; Fu X; Venus S; Guan B-J; Wu J; Gao Z; Banaszuk W; Tchorzewski M; Mu T; Ropelewski P; Merrick WC; Mao Y; Sevval AI; Miranda H; Qian S-B; Manifava M; Ktistakis NT; Vourekas A; Jankowsky E; Topisirovic I; Larsson O; Hatzoglou M
• Article: EMBO JOURNAL. 2019;38(23):e101323

  Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression

  Lorent J; Kusnadi EP; van Hoef V; Rebello RJ; Leibovitch M; Ristau J; Chen S; Lawrence MG; Szkop KJ; Samreen B; Balanathan P; Rapino F; Close P; Bukczynska P; Scharmann K; Takizawa I; Risbridger GP; Selth LA; Leidel SA; Lin Q; Topisirovic I; Larsson O; Furic L
• Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2019;200(3):348-358

  Distinct Cancer-Promoting Stromal Gene Expression Depending on Lung Function

  Sandri BJ; Masvidal L; Murie C; Bartish M; Avdulov S; Higgins L; Markowski T; Peterson M; Bergh J; Yang P; Rolny C; Limper AH; Griffin TJ; Bitterman PB; Wendt CH; Larsson O
• Article: NUCLEIC ACIDS RESEARCH. 2019;47(12):e70

  Generally applicable transcriptome-wide analysis of translation using anota2seq

  Oertlin C; Lorent J; Murie C; Furic L; Topisirovic I; Larsson O
• Article: NUCLEIC ACIDS RESEARCH. 2018;46(1):e3

  Polysome-profiling in small tissue samples

  Liang S; Bellato HM; Lorent J; Lupinacci FCS; Oertlin C; van Hoef V; Andrade VP; Roffe M; Masvidal L; Hajj GNM; Larsson O
• Article: MOLECULAR CELL. 2017;68(5):885-900.e6

  A Unique ISR Program Determines Cellular Responses to Chronic Stress

  Guan B-J; van Hoef V; Jobava R; Elroy-Stein O; Valasek LS; Cargnello M; Gao X-H; Krokowski D; Merrick WC; Kimball SR; Komar AA; Koromilas AE; Wynshaw-Boris A; Topisirovic I; Larsson O; Hatzoglou M
• Article: GENOME RESEARCH. 2016;26(5):636-648

  nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs

  Gandin V; Masvidal L; Hulea L; Gravel S-P; Cargnello M; McLaughlan S; Cai Y; Balanathan P; Morita M; Rajakumar A; Furic L; Pollak M; Porco JAJ; St-Pierre J; Pelletier J; Larsson O; Topisirovic I
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(23):8977-8982

  Distinct perturbation of the translatome by the antidiabetic drug metformin

  Larsson O; Morita M; Topisirovic I; Alain T; Blouin M-J; Pollak M; Sonenberg N
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(50):21487-21492

  Identification of differential translation in genome wide studies

  Larsson O; Sonenberg N; Nadon R
• Article: CANCER RESEARCH. 2007;67(14):6814-6824

  Eukaryotic translation initiation factor 4E-Induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors

  Larsson O; Li S; Issaenko OA; Avdulov S; Peterson M; Smith K; Bitterman PB; Polunovsky VA

Medarbetare och kontakt

Gruppledare

• 

  Ola Larsson

  Senior Forskare | Prefekt | Docent

  Telefon +46852481228

  E-postadress ola.larsson@ki.se

Alla medarbetare i gruppen

• Margarita Bartish

  Anknuten till Forskning

  E-postadress margarita.bartish@ki.se
• Solenne Bleuse

  Postdoktorala Studier

  E-postadress solenne.bleuse@ki.se
• 

  Sherwin Chan

  Biträdande Lektor

  E-postadress sherwin.chan@ki.se
• Arash Darzian Rostami

  Doktorand

  E-postadress arash.darzian.rostami@ki.se
• 

  Adrian Garcia Moreno

  Postdoktorala Studier

  E-postadress adrian.garcia.moreno@ki.se
• Kiana Hosseinpour Moghaddam

  Klinisk Assistent

  E-postadress kiana.hosseinpour.moghaddam@ki.se
• Krzysztof Szkop

  Anknuten till Forskning

  E-postadress krzysztof.szkop@ki.se
• Kathleen Watt

  Forskningsspecialist

  E-postadress kathleen.watt@ki.se
• 

  Alana Panzenhagen

  Postdoktor, Marie Curie

  E-postadress alana.panzenhagen@ki.se

Vår forskargrupp är en del av SciLifeLab

Foto: SciLifeLab

Vår forskargrupp är en del av SciLifeLab

SciLifeLab är ett nationellt samarbete mellan flera svenska lärosäten som samverkar med hälsovård, industri, myndigheter och internationella organisationer. Denna ledande nationella forskningsinfrastruktur och forskningsmiljö inom området molekylär biovetenskap tillhandahåller avancerade teknologier och expertis för grund- och tillämpad livsvetenskap.