Ziegenhain lab

I vår grupp undersöker vi centrala molekylära processer i mänskliga celler, med särskilt fokus på kontrollen av alternativ splicing av transkriberade mRNAs. För detta utvecklar och använder vi nya metoder inom sekvensering av enstaka celler och datorbaserad beräkningsbiologi.

Publikationer

Utvalda publikationer

Article: NATURE BIOTECHNOLOGY. 2022;40(10):1452-1457
Scalable single-cell RNA sequencing from full transcripts with Smart-seq3xpress
Hagemann-Jensen M; Ziegenhain C; Sandberg R
Article: NATURE METHODS. 2022;19(5):560-566
Molecular spikes: a gold standard for single-cell RNA counting
Ziegenhain C; Hendriks G-J; Hagemann-Jensen M; Sandberg R
Article: NATURE GENETICS. 2022;54(3):306-317
Transcriptional kinetics and molecular functions of long noncoding RNAs
Johnsson P; Ziegenhain C; Hartmanis L; Hendriks G-J; Hagemann-Jensen M; Reinius B; Sandberg R
Article: NATURE COMMUNICATIONS. 2021;12(1):6216
BAMboozle removes genetic variation from human sequence data for open data sharing
Ziegenhain C; Sandberg R
Article: NATURE BIOTECHNOLOGY. 2020;38(6):708-714
Single-cell RNA counting at allele and isoform resolution using Smart-seq3
Hagemann-Jensen M; Ziegenhain C; Chen P; Ramskold D; Hendriks G-J; Larsson AJM; Faridani OR; Sandberg R
Article: GIGASCIENCE. 2018;7(6):giy059
zUMIs - A fast and flexible pipeline to process RNA sequencing data with UMIs
Parekh S; Ziegenhain C; Vieth B; Enard W; Hellmann I
Article: MOLECULAR CELL. 2017;65(4):631-643.e4
Comparative Analysis of Single-Cell RNA Sequencing Methods
Ziegenhain C; Vieth B; Parekh S; Reinius B; Guillaumet-Adkins A; Smets M; Leonhardt H; Heyn H; Hellmann I; Enard W
Article: CANCER CELL. 2016;30(6):849-862
Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia
Ebinger S; Oezdemir EZ; Ziegenhain C; Tiedt S; Alves CC; Grunert M; Dworzak M; Lutz C; Turati VA; Enver T; Horny H-P; Sotlar K; Parekh S; Spiekermann K; Hiddemann W; Schepers A; Polzer B; Kirsch S; Hoffmann M; Knapp B; Hasenauer J; Pfeifer H; Panzer-Gruemayer R; Enard W; Gires O; Jeremias I

Ziegenhain lab

Publikationer

Utvalda publikationer

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