Mastcellsbiologi – Forskargrupp Gunnar Nilsson

Publikationer

Utvalda publikationer

• Article: EBIOMEDICINE. 2019;43:150-158

  Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosis.

  Grootens J; Ungerstedt JS; Ekoff M; Rönnberg E; Klimkowska M; Amini R-M; Arock M; Söderlund S; Mattsson M; Nilsson G; Dahlin JS
• Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1361

  Divergent Effects of Acute and Prolonged Interleukin 33 Exposure on Mast Cell IgE-Mediated Functions.

  Rönnberg E; Ghaib A; Ceriol C; Enoksson M; Arock M; Säfholm J; Ekoff M; Nilsson G
• Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2018;314(3):L484-L492

  Mast cell-dependent IL-33/ST2 signaling is protective against the development of airway hyperresponsiveness in a house dust mite mouse model of asthma.

  Zoltowska Nilsson AM; Lei Y; Adner M; Nilsson GP
• Article: FRONTIERS IN IMMUNOLOGY. 2018;9:2193

  An Optimized Protocol for the Isolation and Functional Analysis of Human Lung Mast Cells.

  Ravindran A; Rönnberg E; Dahlin JS; Mazzurana L; Säfholm J; Orre A-C; Al-Ameri M; Peachell P; Adner M; Dahlén S-E; Mjösberg J; Nilsson G
• Article: BLOOD. 2017;130(16):1785-1794

  KIT signaling is dispensable for human mast cell progenitor development.

  Dahlin JS; Ekoff M; Grootens J; Löf L; Amini R-M; Hagberg H; Ungerstedt JS; Olsson-Strömberg U; Nilsson G
• Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2017;47(7):909-917

  Assessment of in vivo mast cell reactivity in patients with systemic mastocytosis.

  Gülen T; Möller Westerberg C; Lyberg K; Ekoff M; Kolmert J; Bood J; Öhd J; James A; Dahlén S-E; Nilsson G; Dahlén B
• Article: ONCOTARGET. 2017;8(6):9647-9659

  Histone deacetylase inhibitor SAHA mediates mast cell death and epigenetic silencing of constitutively active D816V KIT in systemic mastocytosis.

  Lyberg K; Ali HA; Grootens J; Kjellander M; Tirfing M; Arock M; Hägglund H; Nilsson G; Ungerstedt J
• Letter: LEUKEMIA. 2016;30(9):1953-1956

  Detection of circulating mast cells in advanced systemic mastocytosis.

  Dahlin JS; Ungerstedt JS; Grootens J; Sander B; Gülen T; Hägglund H; Nilsson G
• Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2016;46(3):479-490

  The interleukin-33 receptor ST2 is important for the development of peripheral airway hyperresponsiveness and inflammation in a house dust mite mouse model of asthma.

  Zoltowska AM; Lei Y; Fuchs B; Rask C; Adner M; Nilsson GP
• Article: ALLERGY. 2015;70(5):514-521

  Interleukin-33 exacerbates allergic bronchoconstriction in the mice via activation of mast cells.

  Sjöberg LC; Gregory JA; Dahlén S-E; Nilsson GP; Adner M
• Article: JOURNAL OF IMMUNOLOGY. 2015;194(3):1316-1322

  Knockdown of the antiapoptotic Bcl-2 family member A1/Bfl-1 protects mice from anaphylaxis.

  Ottina E; Lyberg K; Sochalska M; Villunger A; Nilsson GP
• Article: PLOS ONE. 2015;10(7):e0133774

  Vaccination against IL-33 Inhibits Airway Hyperresponsiveness and Inflammation in a House Dust Mite Model of Asthma.

  Lei Y; Boinapally V; Zoltowska A; Adner M; Hellman L; Nilsson G
• Editorial comment: LANCET. 2014;383(9928):1608

  Flushing, fatigue, and recurrent anaphylaxis: a delayed diagnosis of mastocytosis.

  Gülen T; Hägglund H; Dahlén S-E; Sander B; Dahlén B; Nilsson G
• Article: BLOOD. 2013;121(3):530-536

  Intraperitoneal influx of neutrophils in response to IL-33 is mast cell-dependent.

  Enoksson M; Möller-Westerberg C; Wicher G; Fallon PG; Forsberg-Nilsson K; Lunderius-Andersson C; Nilsson G
• Article: IMMUNITY. 2011;34(2):258-268

  Mast cells increase vascular permeability by heparin-initiated bradykinin formation in vivo.

  Oschatz C; Maas C; Lecher B; Jansen T; Björkqvist J; Tradler T; Sedlmeier R; Burfeind P; Cichon S; Hammerschmidt S; Müller-Esterl W; Wuillemin WA; Nilsson G; Renné T
• Article: JOURNAL OF IMMUNOLOGY. 2011;186(4):2523-2528

  Mast cells as sensors of cell injury through IL-33 recognition.

  Enoksson M; Lyberg K; Möller-Westerberg C; Fallon PG; Nilsson G; Lunderius-Andersson C
• Article: JOURNAL OF CLINICAL INVESTIGATION. 2006;116(10):2748-2756

  Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion.

  Fischer M; Harvima IT; Carvalho RFS; Möller C; Naukkarinen A; Enblad G; Nilsson G
• Article: BLOOD. 2005;106(4):1330-1336

  Stem cell factor promotes mast cell survival via inactivation of FOXO3a-mediated transcriptional induction and MEK-regulated phosphorylation of the proapoptotic protein Bim.

  Möller C; Alfredsson J; Engström M; Wootz H; Xiang Z; Lennartsson J; Jönsson J-I; Nilsson G

Medlemmar och kontakt

Gruppledare

• 

  Gunnar Nilsson

  Professor | Docent

  E-postadress gunnar.p.nilsson@ki.se

Alla medlemmar i gruppen

• Danijela Apostolovic

  Forskningsspecialist

  E-postadress danijela.apostolovic@ki.se
• Ionut Atanasoai

  Forskningsassistent

  E-postadress ionut.atanasoai@ki.se
• Daryl Zhong Hao Boey

  Assistent Klinisk

  E-postadress daryl.boey.zhong.hao@ki.se
• Ilia Brooke

  Doktorand

  E-postadress ilia.brooke@ki.se
• Joakim Dahlin

  Senior Forskare

  E-postadress joakim.dahlin@ki.se
• Maria Ekoff

  Anknuten till Forskning

  E-postadress maria.ekoff@ki.se
• Yitao Gong

  Doktorand

  E-postadress yitao.gong@ki.se
• 

  Theo Gulen

  Anknuten till Forskning

  E-postadress theo.gulen@ki.se
• Carl Hamsten

  Forskningsspecialist

  E-postadress carl.hamsten@ki.se
• Cristina Iribarren Gomez

  Postdoktor

  E-postadress cristina.iribarren.gomez@ki.se
• Anna-Karin Johnsson

  Senior Lab Manager

  E-postadress anna-karin.johnsson@ki.se
• 

  Annika Jouper

  Administratör

  E-postadress annika.jouper@ki.se
• Jiezhen Mo

  Postdoktor

  E-postadress jiezhen.mo@ki.se
• 

  Gunnar Nilsson

  Professor | Docent

  E-postadress gunnar.p.nilsson@ki.se
• Sofia Papavasileiou

  Doktorand

  E-postadress sofia.papavasileiou@ki.se
• Yueling Peng

  Anknuten till Forskning

  E-postadress yueling.peng@ki.se
• Marija Perusko

  Postdoktor

  E-postadress marija.perusko@ki.se
• 

  Andor Pivarcsi

  Senior Forskare | Docent

  E-postadress andor.pivarcsi@ki.se
• Elin Rönnberg Höckerlind

  Forskningsspecialist

  E-postadress elin.ronnberg.hockerlind@ki.se
• Magnus Tronstad

  Doktorand

  E-postadress magnus.tronstad@ki.se
• 

  Marianne Van Hage

  Professor | Docent

  Telefon +46852483116

  E-postadress marianne.van.hage@ki.se
• Chenyan Wu

  Anknuten till Forskning

  E-postadress chenyan.wu@ki.se