Forskargrupp Liv Eidsmo

Publikationer

Alla gruppmedlemmars publikationer

• Article: CLINICAL AND EXPERIMENTAL DERMATOLOGY. 2024;49(8):793-800

  Investigation of plaque psoriasis relapse after secukinumab withdrawal in patients from two phase III studies

  Lebwohl M; Iversen L; Eidsmo L; Krueger JG; Suarez-Farinas M; Tomalin L; Kolbinger F; You R; Milutinovic M
• Article: BRITISH JOURNAL OF DERMATOLOGY. 2024;190(6):904-914

  Initial steps towards developing a predictive algorithm of disease progression for hidradenitis suppurativa (HS): results from a Cox proportional hazard regression analysis on disease progression among a cohort of 335 Danish patients with HS

  Kjaersgaard Andersen R; Pedersen O; Eidsmo L; Jemec G; Saunte D
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;99(1):e13326

  Method for high-plex analysis of immune cells in human skin using the GeoMx system

  Ignatov B; Sortebech D; Emmanuel T; Zhuravleva E; Eidsmo L
• Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54(1):e2350658

  The cellular microenvironment regulates CX3CR1 expression on CD8⁺ T cells and the maintenance of CX3CR1⁺ CD8⁺ T cells

  Pokharel J; Shryki I; Zwijnenburg AJ; Sandu I; Krumm L; Bekiari C; Avramov V; Heinback R; Lysell J; Eidsmo L; Harris HE; Gerlach C
• Article: IMMUNITY. 2023;56(8):1955-1974.e10

  Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation

  Zwijnenburg AJ; Pokharel J; Varnait R; Zheng W; Hoffer E; Shryki I; Comet NR; Ehrstrom M; Gredmark-Russ S; Eidsmo L; Gerlach C
• Article: IMMUNITY. 2023;56(6):1285-1302.e7

  Human skin-resident CD8+T cells require RUNX2 and RUNX3 for induction of cytotoxicity and expression of the integrin CD49a

  Zitti B; Hoffer E; Zheng W; Pandey RV; Schlums H; Casoni GP; Fusi I; Nguyen L; Karner J; Kokkinou E; Carrasco A; Gahm J; Ehrstrom M; Happaniemi S; Keita AV; Hedin CRH; Mjosberg J; Eidsmo L; Bryceson YT
• Article: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2023;37(5):1004-1016

  Secukinumab demonstrates superiority over narrow-band ultraviolet B phototherapy in new-onset moderate to severe plaque psoriasis patients: Week 52 results from the STEPIn study

  Iversen L; Conrad C; Eidsmo L; Costanzo A; Narbutt J; Pinter A; Kingo K; Rivera Diaz R; Kolbinger F; Nanna M; Frueh JA; Jagiello P
• Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1168684

  Skin infiltrating NK cells in cutaneous T-cell lymphoma are increased in number and display phenotypic alterations partially driven by the tumor

  Scheffschick A; Nenonen J; Xiang M; Winther AH; Ehrstrom M; Wahren-Herlenius M; Eidsmo L; Brauner H
• Letter: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;77(12):3680-3683

  T cells in resolved allergic contact dermatitis steer tissue inflammation and MMP-12-driven tissue modulation

  Gallais Serezal I; Tajpara P; Schonfeldt T; Ignatov B; Sortebech D; Hoffer E; Zhang T; Rooijackers E; Ehrstrom M; Nylen S; Matura M; Melican K; Eidsmo L
• Editorial comment: NEW ENGLAND JOURNAL OF MEDICINE. 2022;387(16):1515-1516

  New Hope for Patients with Vitiligo

  Eidsmo L
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2022;142(3 PT A):705-716

  Single-Cell Analysis Reveals Major Histocompatibility Complex II-Expressing Keratinocytes in Pressure Ulcers with Worse Healing Outcomes

  Li D; Cheng S; Pei Y; Sommar P; Karner J; Herter EK; Toma MA; Zhang L; Pham K; Cheung YT; Liu Z; Chen X; Eidsmo L; Deng Q; Landen NX
• Article: MUCOSAL IMMUNOLOGY. 2022;15(2):257-267

  Intestinal helminth infection transforms the CD4⁺ T cell composition of the skin

  Classon CH; Li M; Clavero AL; Ma J; Feng X; Tibbitt CA; Stark JM; Cardoso R; Ringqvist E; Boon L; Villablanca EJ; Rothfuchs AG; Eidsmo L; Coquet JM; Nylen S
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2022;142(2):333-342.e6

  IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation

  Padhi A; Srivastava A; Ramesh A; Ehrstrom M; Simon M; Sonkoly E; Eidsmo L; Bergman P; Lysell J
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(51):e2100687118

  A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen.

  Landegren N; Ishii N; Aranda-Guillén M; Gunnarsson HI; Sardh F; Hallgren Å; Ståhle M; Hagforsen E; Bradley M; Edqvist P-HD; Pontén F; Mäkitie O; Eidsmo L; Norlén L; Achour A; Dahlbom I; Korponay-Szabó I; Agardh D; Alimohammadi M; Eriksson D; Hashimoto T; Kämpe O
• Article: ADVANCED MATERIALS TECHNOLOGIES. 2021;6(7):2001307

  Vancomycin-Loaded Microneedle Arrays against Methicillin-Resistant Staphylococcus Aureus Skin Infections

  Ziesmer J; Tajpara P; Hempel N-J; Ehrstrom M; Melican K; Eidsmo L; Sotiriou GA
• Article: JAMA DERMATOLOGY. 2021;157(6):1-8

  Long-term Outcomes and Prognosis in New-Onset Psoriasis

  Svedbom A; Mallbris L; Larsson P; Nikamo P; Wolk K; Kjellman P; Sonkoly E; Eidsmo L; Lindqvist U; Stahle M
• Article: COMMUNICATIONS BIOLOGY. 2021;4(1):13

  Skin T cells maintain their diversity and functionality in the elderly

  Koguchi-Yoshioka H; Hoffer E; Cheuk S; Matsumura Y; Vo S; Kjellman P; Grema L; Ishitsuka Y; Nakamura Y; Okiyama N; Fujisawa Y; Fujimoto M; Eidsmo L; Clark RA; Watanabe R
• Review: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2020;92(5):e12953

  Cellular scars and local crosstalk in relapsing psoriasis: an example of a skin sticking disease

  Gallais Serezal I; Cheuk S; Martini E; Eidsmo L
• Article: CELL REPORTS. 2019;29(5):1074-1081.e5

  Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization

  Schulz A; Jiang L; de Vor L; Ehrstrom M; Wermeling F; Eidsmo L; Melican K
• Article: PARASITE IMMUNOLOGY. 2019;41(4):e12618

  Intestinal nematode infection exacerbates experimental visceral leishmaniasis

  Classon C; Feng X; Eidsmo L; Nylen S
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(4):1444-1454

  A skewed pool of resident T cells triggers psoriasis-associated tissue responses in never-lesional skin from patients with psoriasis

  Serezal IG; Hoffer E; Ignatov B; Martini E; Zitti B; Ehrstrom M; Eidsmo L
• Article: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2018;32(11):1930-1939

  Secukinumab treatment in new-onset psoriasis: aiming to understand the potential for disease modification - rationale and design of the randomized, multicenter STEPIn study

  Iversen L; Eidsmo L; Austad J; de Rie M; Osmancevic A; Skov L; Talme T; Bachmann I; van de Kerkhof P; Stahle M; Banerjee R; Oliver J; Fasth AER; Frueh J
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018;138(8):1754-1763

  Resident T Cells in Resolved Psoriasis Steer Tissue Responses that Stratify Clinical Outcome

  Serezal IG; Classon C; Cheuk S; Barrientos-Somarribas M; Wadman E; Martini E; Chang D; Landen NX; Ehrstrom M; Nylen S; Eidsmo L
• Article: JOURNAL OF INFECTIOUS DISEASES. 2018;218(3):453-465

  Human Immunodeficiency Virus-Infected Women Have High Numbers of CD103^-CD8⁺ T Cells Residing Close to the Basal Membrane of the Ectocervical Epithelium

  Gibbs A; Buggert M; Edfeldt G; Ranefall P; Introini A; Cheuk S; Martini E; Eidsmo L; Ball TB; Kimani J; Kaul R; Karlsson AC; Wahlby C; Broliden K; Tjernlund A
• Editorial comment: TRENDS IN IMMUNOLOGY. 2018;39(3):170-172

  Heavy Water Shedding Light on Antigen-Specific T Cell Responses

  Eidsmo L; Gerlach C
• Review: FRONTIERS IN IMMUNOLOGY. 2018;9:300

  Human Langerhans Cells with Pro-inflammatory Features Relocate within Psoriasis Lesions

  Eidsmo L; Martini E
• Editorial comment: IMMUNITY. 2017;47(6):1012-1014

  The Skinny on Fat Trm Cells

  Cheuk S; Eidsmo L
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(12):2630-2638

  MicroRNA-132 with Therapeutic Potential in Chronic Wounds

  Li X; Li D; Wang A; Chu T; Lohcharoenkal W; Zheng X; Grunler J; Narayanan S; Eliasson S; Herter EK; Wang Y; Ma Y; Ehrstrom M; Eidsmo L; Kasper M; Pivarcsi A; Sonkoly E; Catrina S-B; Stahle M; Landen NX
• Letter: EXPERIMENTAL DERMATOLOGY. 2017;26(9):824-827

  Granzyme A potentiates chemokine production in IL-17-stimulated keratinocytes

  Cheuk S; Martini E; Bergh K; Chang D; Rethi B; Stahle M; Eidsmo L
• Letter: EXPERIMENTAL DERMATOLOGY. 2017;26(5):444-446

  IL-22 binding protein regulates murine skin inflammation

  Lindahl H; Martini E; Brauner S; Nikamo P; Serezal IG; Guerreiro-Cacais AO; Jagodic M; Eidsmo L; Stahle M; Olsson T
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(4):865-873

  Dynamic Changes in Resident and Infiltrating Epidermal Dendritic Cells in Active and Resolved Psoriasis

  Martini E; Wiken M; Cheuk S; Serezal IG; Baharom F; Stahle M; Smed-Sorensen A; Eidsmo L
• Article: SCIENTIFIC REPORTS. 2017;7:43989

  Immunogenicity is preferentially induced in sparse dendritic cell cultures

  Nasi A; Bollampalli VP; Sun M; Chen Y; Amu S; Nylen S; Eidsmo L; Rothfuchs AG; Rethi B
• Article: IMMUNITY. 2017;46(2):287-300

  CD49a Expression Defines Tissue-Resident CD8⁺ T Cells Poised for Cytotoxic Function in Human Skin

  Cheuk S; Schlums H; Serezal IG; Martini E; Chiang SC; Marquardt N; Gibbs A; Detlofsson E; Introini A; Forkel M; Hoog C; Tjernlund A; Michaelsson J; Folkersen L; Mjosberg J; Blomqvist L; Ehrstrom M; Stahle M; Bryceson YT; Eidsmo L
• Article: JOURNAL OF IMMUNOLOGY. 2016;197(8):3069-3075

  Fetal CD103⁺ IL-17-Producing Group 3 Innate Lymphoid Cells Represent the Dominant Lymphocyte Subset in Human Amniotic Fluid

  Marquardt N; Ivarsson MA; Sundstrom E; Akesson E; Martini E; Eidsmo L; Mjosberg J; Friberg D; Kublickas M; Ek S; Tegerstedt G; Seiger A; Westgren M; Michaelsson J
• Article: NATURE COMMUNICATIONS. 2016;7:12175

  Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells

  Baptista MAP; Keszei M; Oliveira M; Sunahara KKS; Andersson J; Dahlberg CIM; Worth AJ; Lieden A; Kuo I-C; Wallin RPA; Snapper SB; Eidsmo L; Scheynius A; Karlsson MCI; Bouma G; Burns SO; Forsell MNE; Thrasher AJ; Nylen S; Westerberg LS
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(9):2351-2360

  Composition of Innate Lymphoid Cell Subsets in the Human Skin: Enrichment of NCR⁺ ILC3 in Lesional Skin and Blood of Psoriasis Patients

  Teunissen MBM; Munneke JM; Bernink JH; Spuls PI; Res PCM; te Velde A; Cheuk S; Brouwer MWD; Menting SP; Eidsmo L; Spits H; Hazenberg MD; Mjosberg J
• Review: CLINICAL AND EXPERIMENTAL ALLERGY. 2014;44(8):1033-1043

  Update on innate lymphoid cells in atopic and non-atopic inflammation in the airways and skin

  Mjosberg J; Eidsmo L
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(6):1535-1541

  Genetic Variants of the IL22 Promoter Associate to Onset of Psoriasis before Puberty and Increased IL-22 Production in T Cells

  Nikamo P; Cheuk S; Lysell J; Enerback C; Bergh K; Landen NX; Eidsmo L; Stahle M
• Article: JOURNAL OF IMMUNOLOGY. 2014;192(7):3111-3120

  Epidermal Th22 and Tc17 Cells Form a Localized Disease Memory in Clinically Healed Psoriasis

  Cheuk S; Wiken M; Blomqvist L; Nylen S; Talme T; Stahle M; Eidsmo L
• Review: PARASITE IMMUNOLOGY. 2012;34(12):551-561

  Tissue damage and immunity in cutaneous leishmaniasis

  Nylen S; Eidsmo L
• Article: JOURNAL OF PATHOLOGY. 2012;226(5):806-813

  Reactive murine lymph nodes uniquely permit parenchymal access for T cells that enter via the afferent lymphatics

  Eidsmo L; Stock AT; Heath WR; Bedoui S; Carbone FR
• Review: FRONTIERS IN IMMUNOLOGY. 2012;3:163

  FasL and TRAIL signaling in the skin during cutaneous leishmaniasis - implications for tissue immunopathology and infectious control

  Rethi B; Eidsmo L
• Article: PARASITOLOGY. 2011;138(14):1898-1909

  The interplay between Leishmania promastigotes and human Natural Killer cells in vitro leads to direct lysis of Leishmania by NK cells and modulation of NK cell activity by Leishmania promastigotes

  Lieke T; Nylen S; Eidsmo L; Schmetz C; Berg L; Akuffo H
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2011;131(7):1521-1529

  MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2

  Xu N; Brodin P; Wei T; Meisgen F; Eidsmo L; Nagy N; Kemeny L; Stahle M; Sonkoly E; Pivarcsi A
• Article: PLOS NEGLECTED TROPICAL DISEASES. 2010;4(10):e844

  Systemic FasL and TRAIL Neutralisation Reduce Leishmaniasis Induced Skin Ulceration

  Tasew G; Nylen S; Lieke T; Lemu B; Meless H; Ruffin N; Wolday D; Asseffa A; Yagita H; Britton S; Akuffo H; Chiodi F; Eidsmo L
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2010;126(3):581-9.e1-20-U306

  MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4

  Sonkoly E; Janson P; Majuri M-L; Savinko T; Fyhrquist N; Eidsmo L; Xu N; Meisgen F; Wei T; Bradley M; Stenvang J; Kauppinen S; Alenius H; Lauerma A; Homey B; Winqvist O; Stahle M; Pivarcsi A
• Article: GLOBAL HEALTH ACTION. 2009;2:2046

  Low-cost liquid medium for in vitro cultivation of Leishmania parasites in low-income countries

  Tasew G; Kebede A; Wolday D; Gadisa E; Britton S; Eidsmo L; Akuffo H
• Article: JOURNAL OF IMMUNOLOGY. 2009;182(12):7587-7594

  The C-Type Lectin Clec12A Present on Mouse and Human Dendritic Cells Can Serve as a Target for Antigen Delivery and Enhancement of Antibody Responses

  Lahoud MH; Proietto AI; Ahmet F; Kitsoulis S; Eidsmo L; Wu L; Sathe P; Pietersz S; Chang H-W; Walker ID; Maraskovsky E; Braley H; Lew AM; Wright MD; Heath WR; Shortman K; Caminschi I
• Article: NATURE IMMUNOLOGY. 2009;10(5):524-530

  Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

  Gebhardt T; Wakim LM; Eidsmo L; Reading PC; Heath WR; Carbone FR
• Article: NATURE IMMUNOLOGY. 2009;10(5):488-495

  Cross-presentation of viral and self antigens by skin-derived CD103⁺ dendritic cells

  Bedoui S; Whitney PG; Waithman J; Eidsmo L; Wakim L; Caminschi I; Allan RS; Wojtasiak M; Shortman K; Carbone FR; Brooks AG; Heath WR
• Article: JOURNAL OF IMMUNOLOGY. 2009;182(5):3165-3172

  Differential Migration of Epidermal and Dermal Dendritic Cells during Skin Infection

  Eidsmo L; Allan R; Caminschi I; van Rooijen N; Heath WR; Carbone FR
• Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;153(2):221-230

  Leishmania surface protein gp63 binds directly to human natural killer cells and inhibits proliferation

  Lieke T; Nylen S; Eidsmo L; McMaster WR; Mohammadi AM; Khamesipour A; Berg L; Akuffo H
• Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2007;204(4):805-817

  Splenic accumulation of IL-10 mRNA in T cells distinct from CD4⁺ CD25⁺ (Foxp3) regulatory T cells in human visceral leishmaniasis

  Nylen S; Maurya R; Eidsmo L; Das Manandhar K; Sundar S; Sacks D
• Article: JOURNAL OF IMMUNOLOGY. 2007;178(8):5340-5350

  Potential role for IL-7 in Fas-mediated T cell apoptosis during HIV infection

  Fluur C; De Milito A; Fry TJ; Vivar N; Eidsmo L; Atlas A; Federici C; Matarrese P; Logozzi M; Rajnavolgyi E; Mackall CL; Fais S; Chiodi F; Rethi B
• Article: AMERICAN JOURNAL OF PATHOLOGY. 2007;170(1):227-239

  FasL and TRAIL induce epidermal apoptosis and skin ulceration upon exposure to Leishmania major

  Eidsmo L; Fluur C; Rethi B; Ygberg SE; Ruffin N; De Milito A; Akuffo H; Chiodi F
• Article: VACCINE. 2006;24(47-48):6944-6954

  Surrogate markers of immunity to Leishmania major in leishmanin skin test negative individuals from an endemic area re-visited

  Nylen S; Khamesipour A; Mohammadi A; Jafari-Shakib R; Eidsmo L; Noazin S; Modabber F; Akuffo H
• Thesis / dissertation: 2006

  Dysregulation of receptor induced apoptosis during human leishmaniasis : a possible mechanism of skin ulceration

  Eidsmo, Liv
• Article: AMERICAN JOURNAL OF PATHOLOGY. 2005;166(4):1099-1108

  The contribution of the Fas/FasL apoptotic pathway in ulcer formation during Leishmania major-induced cutaneous leishmaniasis

  Eidsmo L; Nylen S; Khamesipour A; Hedblad MA; Chiodi F; Akuffo H
• Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2002;130(2):307-313

  Alteration of Fas and Fas ligand expression during human visceral leishmaniasis

  Eidsmo L; Wolday D; Berhe N; Sabri F; Satti I; El Hassan AM; Sundar S; Chiodi F; Akuffo H
• Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;117(3):529-534

  Natural killer cells in cross-regulation of IL-12 by IL-10 in Leishmania antigen-stimulated blood donor cells

  Akuffo H; Alexis A; Eidsmo L; Saed A; Nylén S; Maasho K
• Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 1995;52(2):181-186

  STEROID 21-HYDROXYLASE IN THE KIDNEY - DEMONSTRATION OF LEVELS OF MESSENGER-RNA WHICH CORRELATE WITH THE LEVEL OF ACTIVITY

  LAJIC S; EIDSMO L; HOLST M
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Medarbetare och kontakt

Gruppledare

• 

  Liv Eidsmo

  Professor/Överläkare | Docent

  E-postadress liv.eidsmo@ki.se

Alla medarbetare i gruppen

• Ester Bachar-Wikström

  Forskningsspecialist

  E-postadress ester.bachar-wikstrom@ki.se
• 

  Hanna Brauner

  Anknuten till Forskning | Docent

  E-postadress hanna.brauner@ki.se
• 

  Liv Eidsmo

  Professor/Överläkare | Docent

  E-postadress liv.eidsmo@ki.se
• 

  Jonathan Elton

  E-postadress jonathan.elton@ki.se
• Berenice Fischer

  Postdoktorala Studier

  E-postadress berenice.fischer@ki.se
• Elena Hoffer

  Anknuten till Forskning

  E-postadress elena.hoffer@ki.se
• Åsa Krantz

  Doktorand

  E-postadress asa.krantz@ki.se
• Lena Lundeberg

  Anknuten till Undervisning/Handledning | Docent

  E-postadress lena.lundeberg@ki.se
• Thi My Hanh Luong

  Anknuten till Forskning

  E-postadress thi.my.hanh.luong@ki.se
• Josefin Lysell

  Adjungerad Adjunkt

  E-postadress josefin.lysell@ki.se
• 

  Julia Nenonen

  Doktorand

  E-postadress julia.nenonen@ki.se
• 

  Andor Pivarcsi

  Senior Forskare | Docent

  E-postadress andor.pivarcsi@ki.se
• Dawei Song

  Anknuten till Forskning

  E-postadress dawei.song@ki.se
• Despoina Tsakona

  Anknuten till Forskning

  E-postadress despoina.tsakona@ki.se
• Wenning Zheng

  Postdoktorala Studier

  E-postadress wenning.zheng@ki.se
• Ekaterina Zhuravleva

  Anknuten till Forskning

  E-postadress ekaterina.zhuravleva@ki.se