Precision Cancer Medicine i lungcancer - preklinisk, translationell och klinisk forskning – Simon Ekmans forskargrupp

Publikationer

Utvalda publikationer

• Article: MOLECULAR ONCOLOGY. 2021;15(11):2941-2957

  Multiplex immune protein profiling of fine-needle aspirates from patients with non-small-cell lung cancer reveals signatures associated with PD-L1 expression and tumor stage.

  Franzén B; Viktorsson K; Kamali C; Darai-Ramqvist E; Grozman V; Arapi V; Hååg P; Kaminskyy VO; Hydbring P; Kanter L; Nyrén S; Ekman S; De Petris L; Lewensohn R
• Article: JOURNAL OF THORACIC ONCOLOGY. 2021;16(7):1200-1210

  The HILUS-Trial-a Prospective Nordic Multicenter Phase 2 Study of Ultracentral Lung Tumors Treated With Stereotactic Body Radiotherapy.

  Lindberg K; Grozman V; Karlsson K; Lindberg S; Lax I; Wersäll P; Persson GF; Josipovic M; Khalil AA; Moeller DS; Nyman J; Drugge N; Bergström P; Olofsson J; Rogg LV; Ramberg C; Kristiansen C; Jeppesen SS; Nielsen TB; Lödén B; Rosenbrand H-O; Engelholm S; Haraldsson A; Billiet C; Lewensohn R
• Article: ACTA ONCOLOGICA. 2021;60(3):305-311

  Extending hypofractionated stereotactic body radiotherapy to tumours larger than 70cc - effects and side effects.

  Grozman V; Onjukka E; Wersäll P; Lax I; Tsakonas G; Nyren S; Lewensohn R; Lindberg K
• Article: ANNALS OF DIAGNOSTIC PATHOLOGY. 2021;51:151701

  Clinicopathological significance of the expression of PD-L1 in non-small cell lung cancer.

  Montero MA; Aricak O; Kis L; Yoshikawa A; De Petris L; Grundberg O; Pham HHN; Roden AC; Fukuoka J; Attanoos R; Guijarro R; Alarcón F; Lindström K; Ortiz-Villalón C
• Article: EUROPEAN JOURNAL OF CANCER. 2021;145:245-254

  Effect of corticosteroids on the outcome of patients with advanced non-small cell lung cancer treated with immune-checkpoint inhibitors.

  Skribek M; Rounis K; Afshar S; Grundberg O; Friesland S; Tsakonas G; Ekman S; De Petris L
• Article: CANCERS. 2021;13(5):1010

  EPHA2 Interacts with DNA-PKcs in Cell Nucleus and Controls Ionizing Radiation Responses in Non-Small Cell Lung Cancer Cells.

  Kaminskyy VO; Hååg P; Novak M; Végvári Á; Arapi V; Lewensohn R; Viktorsson K
• Article: CANCERS. 2021;13(4):922

  Detection of Tumor-Associated Membrane Receptors on Extracellular Vesicles from Non-Small Cell Lung Cancer Patients via Immuno-PCR.

  Stiller C; Viktorsson K; Paz Gomero E; Hååg P; Arapi V; Kaminskyy VO; Kamali C; De Petris L; Ekman S; Lewensohn R; Karlström AE
• Article: CANCERS. 2020;12(7):E1804-1804

  ALK-Brain Prognostic Index-Preliminary Study of a Prognostic Tool for Patients with ALK-Rearranged, Non-small Cell Lung Cancer and Brain Metastases.

  Tsakonas G; Kamali C; De Petris L; Friesland S; Lewensohn R; Ekman S
• Article: EUROPEAN JOURNAL OF CANCER. 2020;132:24-34

  An immune gene expression signature distinguishes central nervous system metastases from primary tumours in non-small-cell lung cancer.

  Tsakonas G; Lewensohn R; Botling J; Ortiz-Villalon C; Micke P; Friesland S; Nord H; Lindskog M; Sandelin M; Hydbring P; Ekman S
• Article: RADIOTHERAPY AND ONCOLOGY. 2020;146:223-229

  Practice recommendations for lung cancer radiotherapy during the COVID-19 pandemic: An ESTRO-ASTRO consensus statement.

  Guckenberger M; Belka C; Bezjak A; Bradley J; Daly ME; DeRuysscher D; Dziadziuszko R; Faivre-Finn C; Flentje M; Gore E; Higgins KA; Iyengar P; Kavanagh BD; Kumar S; Le Pechoux C; Lievens Y; Lindberg K; McDonald F; Ramella S; Rengan R; Ricardi U; Rimner A; Rodrigues GB; Schild SE; Senan S; Simone CB; Slotman BJ; Stuschke M; Videtic G; Widder J; Yom SS; Palma D
• Article: NATURE MEDICINE. 2020;26(5):665-671

  Caring for patients with cancer in the COVID-19 era.

  van de Haar J; Hoes LR; Coles CE; Seamon K; Fröhling S; Jäger D; Valenza F; de Braud F; De Petris L; Bergh J; Ernberg I; Besse B; Barlesi F; Garralda E; Piris-Giménez A; Baumann M; Apolone G; Soria JC; Tabernero J; Caldas C; Voest EE
• Article: LUNG CANCER. 2020;139:111-117

  Educational level, management and outcomes in small-cell lung cancer (SCLC): A population-based cohort study.

  Tendler S; Holmqvist M; Wagenius G; Lewensohn R; Lambe M; De Petris L
• Article: PLOS ONE. 2020;15(10):e0240973

  The prognostic implications of Notch1, Hes1, Ascl1, and DLL3 protein expression in SCLC patients receiving platinum-based chemotherapy.

  Tendler S; Kanter L; Lewensohn R; Ortiz-Villalón C; Viktorsson K; De Petris L
• Article: ACTA ONCOLOGICA. 2019;58(8):1178-1186

  Radiation-induced brachial plexus toxicity after SBRT of apically located lung lesions.

  Lindberg K; Grozman V; Lindberg S; Onjukka E; Lax I; Lewensohn R; Wersäll P
• Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2019;511(2):260-265

  miR-100-5p confers resistance to ALK tyrosine kinase inhibitors Crizotinib and Lorlatinib in EML4-ALK positive NSCLC.

  Lai Y; Kacal M; Kanony M; Stukan I; Jatta K; Kis L; Norberg E; Vakifahmetoglu-Norberg H; Lewensohn R; Hydbring P; Ekman S
• Article: LUNG CANCER. 2018;124:45-52

  Exosomal RNA-profiling of pleural effusions identifies adenocarcinoma patients through elevated miR-200 and LCN2 expression.

  Hydbring P; De Petris L; Zhang Y; Brandén E; Koyi H; Novak M; Kanter L; Hååg P; Hurley J; Tadigotla V; Zhu B; Skog J; Viktorsson K; Ekman S; Lewensohn R
• Article: CANCER CELL. 2017;31(4):576-590.e8

  Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers.

  Hydbring P; Wang Y; Fassl A; Li X; Matia V; Otto T; Choi YJ; Sweeney KE; Suski JM; Yin H; Bogorad RL; Goel S; Yuzugullu H; Kauffman KJ; Yang J; Jin C; Li Y; Floris D; Swanson R; Ng K; Sicinska E; Anders L; Zhao JJ; Polyak K; Anderson DG; Li C; Sicinski P
• Review: NATURE REVIEWS MOLECULAR CELL BIOLOGY. 2016;17(5):280-292

  Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases.

  Hydbring P; Malumbres M; Sicinski P
• Article: ACTA ONCOLOGICA. 2016;55(2):140-148

  A novel oral insulin-like growth factor-1 receptor pathway modulator and its implications for patients with non-small cell lung carcinoma: A phase I clinical trial.

  Ekman S; Harmenberg J; Frödin J-E; Bergström S; Wassberg C; Eksborg S; Larsson O; Axelson M; Jerling M; Abrahmsen L; Hedlund Å; Alvfors C; Ståhl B; Bergqvist M

Medlemmar och kontakt

Gruppledare

• 

  Simon Ekman

  Professor/Överläkare

  E-postadress simon.ekman@ki.se

Alla medlemmar i gruppen

• Nupur Agarwal

  Anknuten till Forskning

  E-postadress nupur.agarwal@ki.se
• Eike-Benjamin Braune

  Forskare

  E-postadress eike-benjamin.braune@ki.se
• Albano Caceres Verschae

  Postdoktorala Studier

  E-postadress albano.caceres.verschae@ki.se
• Asaf Dan

  Doktorand

  E-postadress asaf.dan@ki.se
• Luigi De Petris

  Anknuten till Forskning

  E-postadress luigi.depetris@ki.se
• 

  Simon Ekman

  Professor/Överläkare

  E-postadress simon.ekman@ki.se
• 

  Bo Franzén

  Anknuten till Forskning

  E-postadress bo.franzen@ki.se
• Signe Friesland

  Anknuten till Forskning

  E-postadress signe.friesland@ki.se
• Ricardo Guijarro

  Anknuten till Forskning

  E-postadress ricardo.guijarro@ki.se
• 

  Maria Helde Frankling

  Anknuten till Forskning

  E-postadress maria.helde.frankling@ki.se
• Koyi Hirsh

  Anknuten till Forskning

  E-postadress hirsh.koyi@ki.se
• Olof Hjorthorn

  Anknuten till Forskning

  E-postadress olof.hjorthorn@ki.se
• 

  Per Hydbring

  Senior Forskningsspecialist | Adjunkt | Docent

  E-postadress per.hydbring@ki.se
• Petra Hååg

  Senior Forskningsinfrastrukturspecialist

  E-postadress petra.haag@ki.se
• Caroline Kamali

  Doktorand

  E-postadress caroline.kamali@ki.se
• 

  Andreas Koulouris

  Doktorand

  E-postadress andreas.koulouris@ki.se
• 

  Rolf Lewensohn

  Professor | Docent

  E-postadress rolf.lewensohn@ki.se
• 

  Karin Lindberg

  Anknuten till Forskning

  E-postadress karin.lindberg@ki.se
• Sara Lindberg

  Anknuten till Forskning

  E-postadress sara.lindberg@ki.se
• Suvesh Munakarmi

  Postdoktorala Studier

  E-postadress suvesh.munakarmi@ki.se
• Konstantinos Rounis

  Anknuten till Forskning

  E-postadress konstantinos.rounis@ki.se
• 

  Adam Sierakowiak

  Anknuten till Forskning

  E-postadress adam.sierakowiak@ki.se
• 

  Marcus Skribek

  Anknuten till Forskning

  E-postadress marcus.skribek@ki.se
• Asimina Talanti

  Forskningsassistent

  E-postadress asimina.talanti@ki.se
• Salomon Tendler

  Anknuten till Forskning

  E-postadress salomon.tendler@ki.se
• Georgios Tsakonas

  Postdoktorala Studier

  E-postadress georgios.tsakonas@ki.se
• 

  Helena Ullgren

  Anknuten till Forskning

  E-postadress helena.ullgren@ki.se
• 

  Kristina Viktorsson

  Senior Forskningsspecialist

  E-postadress kristina.viktorsson@ki.se
• Gunnar Wagenius

  Anknuten till Forskning

  E-postadress gunnar.wagenius@ki.se