Molekulär epidemiologi och åldrande – Sara Häggs forskargrupp

Publikationer

All publications from group members

• Article: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. 2024;95(5):481-484

  Clinical biomarker-based biological ageing and future risk of neurological disorders in the UK Biobank.

  Mak JKL; McMurran CE; Hägg S
• Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2024;:1-12

  Metabolic profiling of smoking, associations with type 2 diabetes and interaction with genetic susceptibility.

  Wei Y; Hägg S; Mak JKL; Tuomi T; Zhan Y; Carlsson S
• Article: AGING CELL. 2024;:e14132

  Effects from medications on functional biomarkers of aging in three longitudinal studies of aging in Sweden.

  Lopes De Oliveira T; Tang B; Bai G; Sjölander A; Jylhävä J; Finkel D; Pedersen NL; Hassing LB; Reynolds CA; Karlsson IK; Hägg S
• Article: AGING CELL. 2024;:e14135

  Epigenome-wide analysis of frailty: Results from two European twin cohorts.

  Mak JKL; Skovgaard AC; Nygaard M; Kananen L; Reynolds CA; Wang Y; Kuja-Halkola R; Karlsson IK; Pedersen NL; Hägg S; Soerensen M; Jylhävä J
• Article: STATISTICS IN MEDICINE. 2024;43(4):731-755

  Combining Mendelian randomization with the sibling comparison design.

  Sjölander A; Frisell T; Öberg S; Wang Y; Hägg S
• Article: GEROSCIENCE. 2024;46(1):961-968

  Associations between psychological resilience and epigenetic clocks in the health and retirement study.

  Zhang A; Zhang Y; Meng Y; Ji Q; Ye M; Zhou L; Liu M; Yi C; Karlsson IK; Fang F; Hägg S; Zhan Y
• Letter: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2024;17(1):e004232

  Associations Between Genetic Variation in the Targets of Low-Density Lipoprotein-Lowering Drugs and Rheumatoid Arthritis.

  Qin C; Hägg S
• Review: NATURE MEDICINE. 2024;30(2):360-372

  Validation of biomarkers of aging.

  Moqri M; Herzog C; Poganik JR; Ying K; Justice JN; Belsky DW; Higgins-Chen AT; Chen BH; Cohen AA; Fuellen G; Hägg S; Marioni RE; Widschwendter M; Fortney K; Fedichev PO; Zhavoronkov A; Barzilai N; Lasky-Su J; Kiel DP; Kennedy BK; Cummings S; Slagboom PE; Verdin E; Maier AB; Sebastiano V; Snyder MP; Gladyshev VN; Horvath S; Ferrucci L
• Preprint: MEDRXIV. 2024;MEDRXIV

  Distinct genomic signatures and modifiable risk factors underly the comorbidity between major depressive disorder and cardiovascular disease.

  Bergstedt J; Pasman JA; Ma Z; Harder A; Yao S; Parker N; Treur JL; Smit DJA; Frei O; Shadrin A; Meijsen JJ; Shen Q; Hägg S; Tornvall P; Buil A; Werge T; Hjerling-Leffler J; Als TD; Børglum AD; Lewis CM; McIntosh AM; Valdimarsdóttir UA; Andreassen OA; Sullivan PF; Lu Y; Fang F
• Article: HELIYON. 2024;10(1):e23415

  Genetically determined telomere length and its association with chronic obstructive pulmonary disease and interstitial lung disease in biobank Japan: A Mendelian randomization study.

  Zhu Y; Meng Y; Zhang Y; Karlsson IK; Hägg S; Zhan Y
• Article: EPIGENETICS. 2023;18(1):2158285

  Leukocyte DNA methylation in Alzheimer´s disease associated genes: replication of findings from neuronal cells.

  Karlsson IK; Ploner A; Wang Y; Gatz M; Pedersen NL; Hägg S
• Article: AMERICAN JOURNAL OF KIDNEY DISEASES. 2023;:S0272-6386(23)00994-0

  Kidney Function Measures and Mortality: A Mendelian Randomization Study.

  Shan Y; Zhang J; Lu Y; Liao J; Liu Y; Dai L; Li J; Song C; Su G; Hägg S; Xiong Z; Nitsch D; Carrero JJ; Huang X
• Article: MOLECULAR GENETICS & GENOMIC MEDICINE. 2023;11(12):e2255

  Rare functional variants in the CRP and G6PC genes modify the relationship between obesity and serum C-reactive protein in white British population.

  Li X; Ploner A; Wang Y; Mak JKL; Lu Y; Magnusson PKE; Jylhävä J; Hägg S
• Article: BRAIN. 2023;146(12):4891-4902

  Advanced biological ageing predicts future risk for neurological diagnoses and clinical examination findings.

  McMurran CE; Wang Y; Mak JKL; Karlsson IK; Tang B; Ploner A; Pedersen NL; Hägg S
• Article: HEALTH SCIENCE REPORTS. 2023;6(11):e1692

  Anticoagulant treatment and COVID-19 mortality among older adults living in nursing homes in Sweden.

  Kananen L; Molnár C; Ansker F; Kozlowska DJ; Hägg S; Jylhävä J; Religa D; Raaschou P
• Review: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2023;:glad251

  Temporal dynamics of epigenetic aging and frailty from midlife to old age.

  Mak JKL; Karlsson IK; Tang B; Wang Y; Pedersen NL; Hägg S; Jylhävä J; Reynolds CA
• Preprint: MEDRXIV. 2023

  Mapping the aetiological foundations of the heart failure spectrum using human genetics

  Henry A; Mo X; Finan C; Chaffin M; Speed D; Issa H; Denaxas S; Ware J; Zheng S; Malarstig A; Gratton J; Bond I; Roselli C; Miller D; Chopade S; Schmidt F; Abner E; Adams L; Andersson C; Aragam K; Ärnlöv J; Asselin G; Axelsson Raja A; Backman J; Bartz T; Biddinger K; Biggs M; Bloom H; Boersma E; Brandimarto J; Brown M; Brunak S; Bruun MT; Buckbinder L; Bundgaard H; Carey D; Chasman D; Chen X; Cook J; Czuba T; de Denus S; Dehghan A; Delgado G; Doney A; Dörr M; Dowsett J; Dudley S; Engström G; Erikstrup C; Esko T; Farber-Eger E; Felix S; Finer S; Ford I; Ghanbari M; Ghasemi S; Ghouse J; Giedraitis V; Giulianini F; Gottdiener J; Gross S; Guðbjartsson D; Gui H; Gutmann R; Hägg S; Haggerty C; Hedman Å; Helgadottir A; Hemingway H; Hillege H; Hyde C; Jensen BA; Jukema W; Kardys I; Karra R; Kavousi M; Kizer J; Kleber M; Køber L; Koekemoer A; Kuchenbaecker K; Lai Y-P; Lanfear D; Langenberg C; Lin H; Lind L; Lindgren C; Liu P; London B; Lowery B; Luan J; Lubitz S; Magnusson P; Margulies K; Marston N; Martin H; März W; Melander O; Mordi I; Morley M; Morris A; Morrison A; Morton L; Nagle M; Nelson C; Niessner A; Niiranen T; Noordam R; Nowak C; O’Donoghue M; Ostrowski SR; Owens A; Palmer C; Paré G; Pedersen OB; Perola M; Pigeyre M; Psaty B; Rice K; Ridker P; Romaine S; Rotter J; Ruff C; Sabatine M; Sallah N; Salomaa V; Sattar N; Shalaby A; Shekhar A; Smelser D; Smith N; Sørensen E; Srinivasan S; Stefansson K; Sveinbjörnsson G; Svensson P; Tammesoo M-L; Tardif J-C; Teder-Laving M; Teumer A; Thorgeirsson G; Thorsteinsdottir U; Torp-Pedersen C; Tragante V; Trompet S; Uitterlinden A; Ullum H; van der Harst P; van Heel D; van Setten J; van Vugt M; Veluchamy A; Verschuuren M; Verweij N; Vissing CR; Völker U; Voors A; Wallentin L; Wang Y; Weeke P; Wiggins K; Williams K; Yang Y; Yu B; Zannad F; Zheng C; Asselbergs F; Cappola T; Dubé M-P; Dunn M; Lang C; Samani N; Shah S; Vasan R; Smith G; Holm H; Shah S; Ellinor P; Hingorani A; Wells Q; Lumbers T; Genes & Health Research Team; DBDS Genomic Consortium; HERMES Consortium
• Preprint: MEDRXIV. 2023

  Deep learning-based prediction of one-year mortality in the entire Finnish population is an accurate but unfair digital marker of aging

  Vabalas A; Hartonen T; Vartiainen P; Jukarainen S; Viippola E; Rodosthenous RS; Liu A; Hägg S; Perola M; Ganna A
• Article: NEUROLOGY. 2023;101(5):e522-e532

  Polygenicity of Comorbid Depression in Multiple Sclerosis.

  Kowalec K; Fitzgerald KC; Salter A; Dolovich C; Harder A; Bernstein CN; Bolton J; Cutter GR; Graff LA; Hägg S; Hitchon CA; Lu Y; Lublin F; McKay KA; Patten SB; Patki A; Tiwari HK; Wolinsky JS; Marrie RA
• Article: AGING CELL. 2023;22(8):e13868

  Unraveling the metabolic underpinnings of frailty using multicohort observational and Mendelian randomization analyses.

  Mak JKL; Kananen L; Qin C; Kuja-Halkola R; Tang B; Lin J; Wang Y; Jääskeläinen T; Koskinen S; Lu Y; Magnusson PKE; Hägg S; Jylhävä J
• Article: BRITISH JOURNAL OF CANCER. 2023;129(1):94-103

  Clinical biomarker-based biological aging and risk of cancer in the UK Biobank.

  Mak JKL; McMurran CE; Kuja-Halkola R; Hall P; Czene K; Jylhävä J; Hägg S
• Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2023;38(7):809-819

  Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study.

  Qin C; Diaz-Gallo L-M; Tang B; Wang Y; Nguyen T-D; Harder A; Lu Y; Padyukov L; Askling J; Hägg S
• Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2023;51(4):587-594

  Comparison of two different frailty scales in the longitudinal Swedish Adoption/Twin Study of Aging (SATSA).

  Wennberg AM; Yin W; Fang F; Pedersen NL; Hägg S; Jylhävä J; Modig K
• Article: NEUROBIOLOGY OF AGING. 2023;126:103-112

  Independent role of Alzheimer's disease genetics and C-reactive protein on cognitive ability in aging.

  Supiyev A; Karlsson R; Wang Y; Koch E; Hägg S; Kauppi K
• Article: GEROSCIENCE. 2023;45(3):2051-2064

  Can frailty scores predict the incidence of cancer? Results from two large population-based studies.

  Mak JKL; Kuja-Halkola R; Wang Y; Hägg S; Jylhävä J
• Article: GEROSCIENCE. 2023;45(3):2065-2078

  Longitudinal associations between use of antihypertensive, antidiabetic, and lipid-lowering medications and biological aging.

  Tang B; Li X; Wang Y; Sjölander A; Johnell K; Thambisetty M; Ferrucci L; Reynolds CA; Finkel D; Jylhävä J; Pedersen NL; Hägg S
• Article: CARDIOVASCULAR RESEARCH. 2023;119(4):998-1007

  Low leukocyte mitochondrial DNA abundance drives atherosclerotic cardiovascular diseases: a cohort and Mendelian randomization study.

  Luo J; Noordam R; Jukema JW; van Dijk KW; Hägg S; Grassmann F; le Cessie S; van Heemst D
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(3):316-323

  Occupational inhalable agents constitute major risk factors for rheumatoid arthritis, particularly in the context of genetic predisposition and smoking.

  Tang B; Liu Q; Ilar A; Wiebert P; Hägg S; Padyukov L; Klareskog L; Alfredsson L; Jiang X
• Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2023;78(2):333-341

  Genetic and Environmental Influences on Longitudinal Frailty Trajectories From Adulthood into Old Age.

  Mak JKL; Kuja-Halkola R; Bai G; Hassing LB; Pedersen NL; Hägg S; Jylhävä J; Reynolds CA
• Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):716

  Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.

  de Rojas I; Moreno-Grau S; Tesi N; Grenier-Boley B; Andrade V; Jansen IE; Pedersen NL; Stringa N; Zettergren A; Hernández I; Montrreal L; Antúnez C; Antonell A; Tankard RM; Bis JC; Sims R; Bellenguez C; Quintela I; González-Perez A; Calero M; Franco-Macías E; Macías J; Blesa R; Cervera-Carles L; Menéndez-González M; Frank-García A; Royo JL; Moreno F; Huerto Vilas R; Baquero M; Diez-Fairen M; Lage C; García-Madrona S; García-González P; Alarcón-Martín E; Valero S; Sotolongo-Grau O; Ullgren A; Naj AC; Lemstra AW; Benaque A; Pérez-Cordón A; Benussi A; Rábano A; Padovani A; Squassina A; de Mendonça A; Arias Pastor A; Kok AAL; Meggy A; Pastor AB; Espinosa A; Corma-Gómez A; Martín Montes A; Sanabria Á; DeStefano AL; Schneider A; Haapasalo A; Kinhult Ståhlbom A; Tybjærg-Hansen A; Hartmann AM; Spottke A; Corbatón-Anchuelo A; Rongve A; Borroni B; Arosio B; Nacmias B; Nordestgaard BG; Kunkle BW; Charbonnier C; Abdelnour C; Masullo C; Martínez Rodríguez C; Muñoz-Fernandez C; Dufouil C; Graff C; Ferreira CB; Chillotti C; Reynolds CA; Fenoglio C; Van Broeckhoven C; Clark C; Pisanu C; Satizabal CL; Holmes C; Buiza-Rueda D; Aarsland D; Rujescu D; Alcolea D; Galimberti D; Wallon D; Seripa D; Grünblatt E; Dardiotis E; Düzel E; Scarpini E; Conti E; Rubino E; Gelpi E; Rodriguez-Rodriguez E; Duron E; Boerwinkle E; Ferri E; Tagliavini F; Küçükali F; Pasquier F; Sanchez-Garcia F; Mangialasche F; Jessen F; Nicolas G; Selbæk G; Ortega G; Chêne G; Hadjigeorgiou G; Rossi G; Spalletta G; Giaccone G; Grande G; Binetti G; Papenberg G; Hampel H; Bailly H; Zetterberg H; Soininen H; Karlsson IK; Alvarez I; Appollonio I; Giegling I; Skoog I; Saltvedt I; Rainero I; Rosas Allende I; Hort J; Diehl-Schmid J; Van Dongen J; Vidal J-S; Lehtisalo J; Wiltfang J; Thomassen JQ; Kornhuber J; Haines JL; Vogelgsang J; Pineda JA; Fortea J; Popp J; Deckert J; Buerger K; Morgan K; Fließbach K; Sleegers K; Molina-Porcel L; Kilander L; Weinhold L; Farrer LA; Wang L-S; Kleineidam L; Farotti L; Parnetti L; Tremolizzo L; Hausner L; Benussi L; Froelich L; Ikram MA; Deniz-Naranjo MC; Tsolaki M; Rosende-Roca M; Löwenmark M; Hulsman M; Spallazzi M; Pericak-Vance MA; Esiri M; Bernal Sánchez-Arjona M; Dalmasso MC; Martínez-Larrad MT; Arcaro M; Nöthen MM; Fernández-Fuertes M; Dichgans M; Ingelsson M; Herrmann MJ; Scherer M; Vyhnalek M; Kosmidis MH; Yannakoulia M; Schmid M; Ewers M; Heneka MT; Wagner M; Scamosci M; Kivipelto M; Hiltunen M; Zulaica M; Alegret M; Fornage M; Roberto N; van Schoor NM; Seidu NM; Banaj N; Armstrong NJ; Scarmeas N; Scherbaum N; Goldhardt O; Hanon O; Peters O; Skrobot OA; Quenez O; Lerch O; Bossù P; Caffarra P; Dionigi Rossi P; Sakka P; Mecocci P; Hoffmann P; Holmans PA; Fischer P; Riederer P; Yang Q; Marshall R; Kalaria RN; Mayeux R; Vandenberghe R; Cecchetti R; Ghidoni R; Frikke-Schmidt R; Sorbi S; Hägg S; Engelborghs S; Helisalmi S; Botne Sando S; Kern S; Archetti S; Boschi S; Fostinelli S; Gil S; Mendoza S; Mead S; Ciccone S; Djurovic S; Heilmann-Heimbach S; Riedel-Heller S; Kuulasmaa T; Del Ser T; Lebouvier T; Polak T; Ngandu T; Grimmer T; Bessi V; Escott-Price V; Giedraitis V; Deramecourt V; Maier W; Jian X; Pijnenburg YAL; EADB contributors; GR@ACE study group; DEGESCO consortium; IGAP (ADGC, CHARGE, EADI, GERAD); PGC-ALZ consortia; Kehoe PG; Garcia-Ribas G; Sánchez-Juan P; Pastor P; Pérez-Tur J; Piñol-Ripoll G; Lopez de Munain A; García-Alberca JM; Bullido MJ; Álvarez V; Lleó A; Real LM; Mir P; Medina M; Scheltens P; Holstege H; Marquié M; Sáez ME; Carracedo Á; Amouyel P; Schellenberg GD; Williams J; Seshadri S; van Duijn CM; Mather KA; Sánchez-Valle R; Serrano-Ríos M; Orellana A; Tárraga L; Blennow K; Huisman M; Andreassen OA; Posthuma D; Clarimón J; Boada M; van der Flier WM; Ramirez A; Lambert J-C; van der Lee SJ; Ruiz A
• Thesis / dissertation: 2023

  Epidemiological studies on frailty and its associations with mortality, dementia, and polypharmacy

  Bai, Ge
• Article: ALZHEIMERS RESEARCH & THERAPY. 2023;15(1):5

  Dementia and psychotropic medications are associated with significantly higher mortality in geriatric patients hospitalized with COVID-19: data from the StockholmGeroCovid project.

  Secnik J; Eriksdotter M; Xu H; Annetorp M; SweGeroCOVID Project; Rytarowski A; Johnell K; Hägg S; Religa D
• Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2023;31:311-312

  Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study

  Qin C; Diaz-Gallo LM; Tang B; Wang Y; Padyukov L; Askling J; Hagg S
• Article: GERONTOLOGY. 2023;69(4):396-405

  Two Years with COVID-19: The Electronic Frailty Index Identifies High-Risk Patients in the Stockholm GeroCovid Study.

  Mak JKL; Eriksdotter M; Annetorp M; Kuja-Halkola R; Kananen L; Boström A-M; Kivipelto M; Metzner C; Bäck Jerlardtz V; Engström M; Johnson P; Lundberg LG; Åkesson E; Sühl Öberg C; Olsson M; Cederholm T; Hägg S; Religa D; Jylhävä J
• Article: EPIGENETICS COMMUNICATIONS. 2023;3(1):7

  Connections between cross-tissue and intra-tissue biomarkers of aging biology in older adults.

  Waziry R; Gu Y; Williams O; Hägg S
• Conference publication: ANNALS OF NUTRITION AND METABOLISM. 2023;79:25

  The importance of nutrition for dementia and frailty: Evidence from epidemiological studies in aging

  Hagg S
• Article: GERONTOLOGY. 2023;69(12):1385-1393

  Is Frailty Different in Younger Adults Compared to Old? Prevalence, Characteristics, and Risk Factors of Early-Life and Late-Life Frailty in Samples from Sweden and UK.

  Bai G; Wang Y; Mak JKL; Ericsson M; Hägg S; Jylhävä J
• Article: PLOS ONE. 2023;18(3):e0283344

  Health progression for Covid-19 survivors hospitalized in geriatric clinics in Sweden.

  Kananen L; Hong X; Annetorp M; Mak JKL; Jylhävä J; Eriksdotter M; Hägg S; Religa D
• Conference publication: INNOVATION IN AGING. 2022;6:243

  FUNCTIONAL AGING TRAJECTORIES AND DRUG INTERACTIONS

  Deliveira TL; Hagg S
• Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2022;37(12):1261-1271

  Adiposity and the risk of dementia: mediating effects from inflammation and lipid levels.

  Karlsson IK; Zhan Y; Wang Y; Li X; Jylhävä J; Hägg S; Dahl Aslan AK; Gatz M; Pedersen NL; Reynolds CA
• Article: CLINICAL NUTRITION. 2022;41(12):2973-2979

  Body mass index and Mini Nutritional Assessment-Short Form as predictors of in-geriatric hospital mortality in older adults with COVID-19.

  Kananen L; Eriksdotter M; Boström AM; Kivipelto M; Annetorp M; Metzner C; Bäck Jerlardtz V; Engström M; Johnson P; Lundberg LG; Åkesson E; Sühl Öberg C; Hägg S; Religa D; Jylhävä J; Cederholm T
• Article: CLINICAL EPIGENETICS. 2022;14(1):153

  Dynamic patterns of blood lipids and DNA methylation in response to statin therapy.

  Qin X; Wang Y; Pedersen NL; Tang B; Hägg S
• Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2022;77(11):2311-2319

  Development of an Electronic Frailty Index for Hospitalized Older Adults in Sweden.

  Mak JKL; Hägg S; Eriksdotter M; Annetorp M; Kuja-Halkola R; Kananen L; Boström A-M; Kivipelto M; Metzner C; Bäck Jerlardtz V; Engström M; Johnson P; Lundberg LG; Åkesson E; Sühl Öberg C; Olsson M; Cederholm T; Jylhävä J; Religa D
• Article: DIABETOLOGIA. 2022;65(10):1676-1686

  Assessment of the bi-directional relationship between blood mitochondrial DNA copy number and type 2 diabetes mellitus: a multivariable-adjusted regression and Mendelian randomisation study.

  Wang W; Luo J; Willems van Dijk K; Hägg S; Grassmann F; T Hart LM; van Heemst D; Noordam R
• Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:e198

  T55. POLYGENICITY OF COMORBID DEPRESSION IN MULTIPLE SCLEROSIS

  Kowalec K; Salter A; Fitzgerald KC; Harder A; Lu Y; Dolovich C; Hägg S; Hitchon C; Bernstein CN; Cutter G; Bolton JM; McKay K; Graff LA; Patten S; Marrie RA
• Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2022;63:E50

  GENETIC EPIDEMIOLOGY AND POLYGENICITY OF PSYCHOTIC MAJOR DEPRESSIVE DISORDER

  Thi TDN; Kuja-Halkola R; Kowalec K; Harder A; Xiong Y; Landen M; Hagg S; Lichtenstein P; Larsson H; Buil A; Meijsen J; Sullivan P; Dalman C; Pasman J; Lu Y
• Article: EPIGENOMICS. 2022;14(18):1105-1124

  Methylation status of VTRNA2-1/nc886 is stable across populations, monozygotic twin pairs and in majority of tissues.

  Marttila S; Tamminen H; Rajić S; Mishra PP; Lehtimäki T; Raitakari O; Kähönen M; Kananen L; Jylhävä J; Hägg S; Delerue T; Peters A; Waldenberger M; Kleber ME; März W; Luoto R; Raitanen J; Sillanpää E; Laakkonen EK; Heikkinen A; Ollikainen M; Raitoharju E
• Article: NEUROLOGY. 2022;99(7):e650-e659

  Genetic Variation in Targets of Antidiabetic Drugs and Alzheimer Disease Risk: A Mendelian Randomization Study.

  Tang B; Wang Y; Jiang X; Thambisetty M; Ferrucci L; Johnell K; Hägg S
• Editorial comment: NATURE MICROBIOLOGY. 2022;7(8):1106-1107

  COVID vaccination in older adults.

  Hägg S; Religa D
• Article: ATHEROSCLEROSIS. 2022;354:1-7

  The association between mitochondrial DNA abundance and stroke: A combination of multivariable-adjusted survival and Mendelian randomization analyses.

  Martens LG; Luo J; Wermer MJH; Willems van Dijk K; Hägg S; Grassmann F; Noordam R; van Heemst D
• Article: NATURE AGING. 2022;2(7):644-661

  A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking.

  Higgins-Chen AT; Thrush KL; Wang Y; Minteer CJ; Kuo P-L; Wang M; Niimi P; Sturm G; Lin J; Moore AZ; Bandinelli S; Vinkers CH; Vermetten E; Rutten BPF; Geuze E; Okhuijsen-Pfeifer C; van der Horst MZ; Schreiter S; Gutwinski S; Luykx JJ; Picard M; Ferrucci L; Crimmins EM; Boks MP; Hägg S; Hu-Seliger TT; Levine ME
• Preprint: BIORXIV. 2022

  Methylation status of VTRNA2-1/nc886 is stable across human populations, monozygotic twin pairs and in majority of somatic tissues

  Marttila S; Tamminen H; Rajić S; Mishra P; Lehtimäki T; Raitakari O; Kähönen M; Kananen L; Jylhävä J; Hägg S; Delerue T; Peters A; Waldenberger M; Kleber M; März W; Luoto R; Raitanen J; Sillanpää E; Laakkonen E; Heikkinen A; Ollikainen M; Raitoharju E
• Article: NATURE GENETICS. 2022;54(5):581-592

  Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects.

  Howe LJ; Nivard MG; Morris TT; Hansen AF; Rasheed H; Cho Y; Chittoor G; Ahlskog R; Lind PA; Palviainen T; van der Zee MD; Cheesman R; Mangino M; Wang Y; Li S; Klaric L; Ratliff SM; Bielak LF; Nygaard M; Giannelis A; Willoughby EA; Reynolds CA; Balbona JV; Andreassen OA; Ask H; Baras A; Bauer CR; Boomsma DI; Campbell A; Campbell H; Chen Z; Christofidou P; Corfield E; Dahm CC; Dokuru DR; Evans LM; de Geus EJC; Giddaluru S; Gordon SD; Harden KP; Hill WD; Hughes A; Kerr SM; Kim Y; Kweon H; Latvala A; Lawlor DA; Li L; Lin K; Magnus P; Magnusson PKE; Mallard TT; Martikainen P; Mills MC; Njølstad PR; Overton JD; Pedersen NL; Porteous DJ; Reid J; Silventoinen K; Southey MC; Stoltenberg C; Tucker-Drob EM; Wright MJ; Social Science Genetic Association Consortium; Within Family Consortium; Hewitt JK; Keller MC; Stallings MC; Lee JJ; Christensen K; Kardia SLR; Peyser PA; Smith JA; Wilson JF; Hopper JL; Hägg S; Spector TD; Pingault J-B; Plomin R; Havdahl A; Bartels M; Martin NG; Oskarsson S; Justice AE; Millwood IY; Hveem K; Naess Ø; Willer CJ; Åsvold BO; Koellinger PD; Kaprio J; Medland SE; Walters RG; Benjamin DJ; Turley P; Evans DM; Davey Smith G; Hayward C; Brumpton B; Hemani G; Davies NM
• Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):124

  Genetics of age-at-onset in major depression.

  Harder A; Nguyen T-D; Pasman JA; Mosing MA; Hägg S; Lu Y
• Preprint: RESEARCH SQUARE. 2022

  Leukocyte DNA methylation in Alzheimer´s disease associated genes: replication of findings from neuronal cells

  Karlsson IK; Ploner A; Wang Y; Gatz M; Pedersen NL; Hägg S
• Preprint: MEDRXIV. 2022

  Adiposity and the risk of dementia: mediating effects from inflammation and lipid levels

  Karlsson I; Zhan Y; Wang Y; Li X; Jylhava J; Hagg S; Dahl Aslan A; Gatz M; Pedersen N; Reynolds C
• Article: MOLECULAR PSYCHIATRY. 2022;27(3):1667-1675

  Genetic heterogeneity and subtypes of major depression.

  Nguyen T-D; Harder A; Xiong Y; Kowalec K; Hägg S; Cai N; Kuja-Halkola R; Dalman C; Sullivan PF; Lu Y
• Journal article: NPJ PARKINSONS DISEASE. 2022;8(1):14

  Metabolite and lipoprotein profiles reveal sex-related oxidative stress imbalance in de novo drug-naive Parkinson's disease patients.

  Meoni G; Tenori L; Schade S; Licari C; Pirazzini C; Bacalini MG; Garagnani P; Turano P; PROPAG-AGEING Consortium; Trenkwalder C; Franceschi C; Mollenhauer B; Luchinat C
• Letter: CLINICAL NUTRITION. 2022;41(2):573-574

  Response to Letter to the Editor: Comment on "Body mass index and Mini Nutritional Assessment-Short Form as predictors of in-geriatric hospital mortality in older adults with COVID-19" (by Café Balcı, MD, Hacettepe University Faculty of Medicine Department of Internal Medicine Division of Geriatric Medicine).

  Kananen L; Religa D; Eriksdotter M; Hägg S; Julhävä J; Cederholm T
• Editorial comment: NATURE AGING. 2022;2(2):102-104

  Telomere research entering the big data era.

  Hägg S; Zhan Y
• Article: SCIENTIFIC REPORTS. 2022;12(1):1330

  Early downregulation of hsa-miR-144-3p in serum from drug-naïve Parkinson's disease patients.

  Zago E; Dal Molin A; Dimitri GM; Xumerle L; Pirazzini C; Bacalini MG; Maturo MG; Azevedo T; Spasov S; Gómez-Garre P; Periñán MT; Jesús S; Baldelli L; Sambati L; Calandra-Buonaura G; Garagnani P; Provini F; Cortelli P; Mir P; Trenkwalder C; Mollenhauer B; Franceschi C; Liò P; Nardini C; PROPAG-AGEING Consortium
• Article: JOURNAL OF NUTRITION. 2022;152(1):269-275

  Protein Nutritional Status and Frailty: A Mendelian Randomization Study.

  Tomata Y; Wang Y; Hägg S; Jylhävä J
• Article: PAIN. 2022;163(1):e40-e48

  Reciprocal interaction between depression and pain: results from a comprehensive bidirectional Mendelian randomization study and functional annotation analysis.

  Tang B; Meng W; Hägg S; Burgess S; Jiang X
• Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2022;29:146

  Dementia and antipsychotics are associated with significantly higher mortality in patients with COVID-19

  Secnik J; Eriksdotter M; Rytarowski A; Annetorp M; Johnell K; Hagg S; Religa D
• Conference publication: ARTHRITIS & RHEUMATOLOGY. 2022;74:1207-1209

  Occupational Inhaled Agents Constitute Major Risk Factors for Rheumatoid Arthritis, Particularly in the Context of Genetic Predisposition and Smoking

  Tang B; Liu Q; Ilar A; Wiebert P; Hagg S; Padyukov L; Klareskog L; Alfredsson L; Jiang X
• Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):212

  Polygenicity of comorbid depression in multiple sclerosis

  Kowalec K; Salter A; Fitzgerald KC; Harder A; Lu Y; Dolovich C; Hagg S; Hitchon C; Bernstein CN; Cutter G; Marriott JJ; Bolton JM; McKay K; Graff LA; Patten S; Marrie RA
• Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2022;29:692

  Clinical outcome of patients with hip fracture and dementia. Data on 7876 patients from Swedish registry SveDem

  Religa D; Hagg S; Gustavsson F; Hedstrom M
• Conference publication: INNOVATION IN AGING. 2021;5:5

  A COMPUTATIONAL SOLUTION TO BOLSTER EPIGENETIC CLOCK RELIABILITY FOR CLINICAL TRIALS AND LONGITUDINAL TRACKING

  Higgins-Chen A; Thrush K; Hu-Seliger T; Wang Y; Hagg S; Levine M
• Preprint: MEDRXIV. 2021

  Using an electronic frailty index to predict adverse outcomes in geriatric COVID-19 patients: data from the Stockholm GeroCovid study

  Mak J; Eriksdotter M; Annetorp M; Kuja-Halkola R; Kananen L; Boström A-M; Kivipelto M; Metzner C; Jerlardtz VB; Engström M; Johnson P; Lundberg LG; Åkesson E; Öberg CS; Olsson M; Cederholm T; Hägg S; Religa D; Jylhävä J
• Preprint: MEDRXIV. 2021

  Development of an electronic frailty index for hospitalized geriatric patients in Sweden

  Mak J; Hägg S; Eriksdotter M; Annetorp M; Kuja-Halkola R; Kananen L; Boström A-M; Kivipelto M; Metzner C; Jerlardtz VB; Engström M; Johnson P; Lundberg LG; Åkesson E; Öberg CS; Olsson M; Cederholm T; Jylhävä J; Religa D
• Article: AGE AND AGEING. 2021;50(6):2174-2182

  Frailty trajectories in three longitudinal studies of aging: Is the level or the rate of change more predictive of mortality?

  Bai G; Szwajda A; Wang Y; Li X; Bower H; Karlsson IK; Johansson B; Dahl Aslan AK; Pedersen NL; Hägg S; Jylhävä J
• Preprint: MEDRXIV. 2021

  The association between lymphocyte mitochondrial DNA abundance and Stroke: a combination of multivariable-adjusted survival and mendelian randomization analyses

  Martens L; Luo J; Wermer M; van Dijk KW; Hägg S; Grassmann F; Noordam R; van Heemst D
• Article: BMC MEDICINE. 2021;19(1):248

  Frailty and the risk of dementia: is the association explained by shared environmental and genetic factors?

  Bai G; Wang Y; Kuja-Halkola R; Li X; Tomata Y; Karlsson IK; Pedersen NL; Hägg S; Jylhävä J
• Article: NUTRIENTS. 2021;13(10):3539

  Fatty Acids and Frailty: A Mendelian Randomization Study.

  Tomata Y; Wang Y; Hägg S; Jylhävä J
• Thesis / dissertation: 2021

  Biological ages : correlations, genetic determinants, and health outcomes

  Li, Xia
• Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;51:E109-E110

  GENETICS OF AGE-AT-ONSET IN MAJOR DEPRESSION

  Harder A; Thi TDN; Mosing MA; Hagg S; Lu Y
• Journal article: NPJ PARKINSONS DISEASE. 2021;7(1):78

  Heterogeneity of prodromal Parkinson symptoms in siblings of Parkinson disease patients.

  Baldelli L; Schade S; Jesús S; Schreglmann SR; Sambati L; Gómez-Garre P; Halsband C; Calandra-Buonaura G; Adarmes-Gómez AD; Sixel-Döring F; Zenesini C; Pirazzini C; Garagnani P; Bacalini MG; Bhatia KP; Cortelli P; Mollenhauer B; Franceschi C; PROPAG-AGEING consortium; Mir P; Trenkwalder C; Provini F
• Review: JOURNAL OF INTERNAL MEDICINE. 2021;290(3):602-620

  Technological readiness and implementation of genomic-driven precision medicine for complex diseases.

  Franks PW; Melén E; Friedman M; Sundström J; Kockum I; Klareskog L; Almqvist C; Bergen SE; Czene K; Hägg S; Hall P; Johnell K; Malarstig A; Catrina A; Hagström H; Benson M; Gustav Smith J; Gomez MF; Orho-Melander M; Jacobsson B; Halfvarson J; Repsilber D; Oresic M; Jern C; Melin B; Ohlsson C; Fall T; Rönnblom L; Wadelius M; Nordmark G; Johansson Å; Rosenquist R; Sullivan PF
• Article: AGING CELL. 2021;20(9):e13459

  A genome-wide association study of the frailty index highlights brain pathways in ageing.

  Atkins JL; Jylhävä J; Pedersen NL; Magnusson PK; Lu Y; Wang Y; Hägg S; Melzer D; Williams DM; Pilling LC
• Article: AGING-US. 2021;13(13):16990-17023

  Sex differences in genetic and environmental influences on frailty and its relation to body mass index and education.

  Mak JKL; Reynolds CA; Hägg S; Li X; Ericsson M; Pedersen NL; Jylhävä J; Kuja-Halkola R
• Preprint: MEDRXIV. 2021

  Low mitochondrial copy number drives atherogenic cardiovascular disease: evidence from prospective cohort analyses in the UK Biobank combined with Mendelian Randomization

  Luo J; Noordam R; Jukema W; van Dijk KW; Hägg S; Grassmann F; Cessie SL; van Heemst D
• Article: GENOME BIOLOGY. 2021;22(1):194

  Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging.

  McCartney DL; Min JL; Richmond RC; Lu AT; Sobczyk MK; Davies G; Broer L; Guo X; Jeong A; Jung J; Kasela S; Katrinli S; Kuo P-L; Matias-Garcia PR; Mishra PP; Nygaard M; Palviainen T; Patki A; Raffield LM; Ratliff SM; Richardson TG; Robinson O; Soerensen M; Sun D; Tsai P-C; van der Zee MD; Walker RM; Wang X; Wang Y; Xia R; Xu Z; Yao J; Zhao W; Correa A; Boerwinkle E; Dugué P-A; Durda P; Elliott HR; Gieger C; Genetics of DNA Methylation Consortium; de Geus EJC; Harris SE; Hemani G; Imboden M; Kähönen M; Kardia SLR; Kresovich JK; Li S; Lunetta KL; Mangino M; Mason D; McIntosh AM; Mengel-From J; Moore AZ; Murabito JM; NHLBI Trans-Omics for Precision Medicine (TOPMed) ; Ollikainen M; Pankow JS; Pedersen NL; Peters A; Polidoro S; Porteous DJ; Raitakari O; Rich SS; Sandler DP; Sillanpää E; Smith AK; Southey MC; Strauch K; Tiwari H; Tanaka T; Tillin T; Uitterlinden AG; Van Den Berg DJ; van Dongen J; Wilson JG; Wright J; Yet I; Arnett D; Bandinelli S; Bell JT; Binder AM; Boomsma DI; Chen W; Christensen K; Conneely KN; Elliott P; Ferrucci L; Fornage M; Hägg S; Hayward C; Irvin M; Kaprio J; Lawlor DA; Lehtimäki T; Lohoff FW; Milani L; Milne RL; Probst-Hensch N; Reiner AP; Ritz B; Rotter JI; Smith JA; Taylor JA; van Meurs JBJ; Vineis P; Waldenberger M; Deary IJ; Relton CL; Horvath S; Marioni RE
• Article: CLINICAL EPIGENETICS. 2021;13(1):129

  The epigenetic etiology of cardiovascular disease in a longitudinal Swedish twin study.

  Qin X; Karlsson IK; Wang Y; Li X; Pedersen N; Reynolds CA; Hägg S
• Article: NATURE COMMUNICATIONS. 2021;12(1):3417

  Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.

  de Rojas I; Moreno-Grau S; Tesi N; Grenier-Boley B; Andrade V; Jansen IE; Pedersen NL; Stringa N; Zettergren A; Hernández I; Montrreal L; Antúnez C; Antonell A; Tankard RM; Bis JC; Sims R; Bellenguez C; Quintela I; González-Perez A; Calero M; Franco-Macías E; Macías J; Blesa R; Cervera-Carles L; Menéndez-González M; Frank-García A; Royo JL; Moreno F; Huerto Vilas R; Baquero M; Diez-Fairen M; Lage C; García-Madrona S; García-González P; Alarcón-Martín E; Valero S; Sotolongo-Grau O; Ullgren A; Naj AC; Lemstra AW; Benaque A; Pérez-Cordón A; Benussi A; Rábano A; Padovani A; Squassina A; de Mendonça A; Arias Pastor A; Kok AAL; Meggy A; Pastor AB; Espinosa A; Corma-Gómez A; Martín Montes A; Sanabria Á; DeStefano AL; Schneider A; Haapasalo A; Kinhult Ståhlbom A; Tybjærg-Hansen A; Hartmann AM; Spottke A; Corbatón-Anchuelo A; Rongve A; Borroni B; Arosio B; Nacmias B; Nordestgaard BG; Kunkle BW; Charbonnier C; Abdelnour C; Masullo C; Martínez Rodríguez C; Muñoz-Fernandez C; Dufouil C; Graff C; Ferreira CB; Chillotti C; Reynolds CA; Fenoglio C; Van Broeckhoven C; Clark C; Pisanu C; Satizabal CL; Holmes C; Buiza-Rueda D; Aarsland D; Rujescu D; Alcolea D; Galimberti D; Wallon D; Seripa D; Grünblatt E; Dardiotis E; Düzel E; Scarpini E; Conti E; Rubino E; Gelpi E; Rodriguez-Rodriguez E; Duron E; Boerwinkle E; Ferri E; Tagliavini F; Küçükali F; Pasquier F; Sanchez-Garcia F; Mangialasche F; Jessen F; Nicolas G; Selbæk G; Ortega G; Chêne G; Hadjigeorgiou G; Rossi G; Spalletta G; Giaccone G; Grande G; Binetti G; Papenberg G; Hampel H; Bailly H; Zetterberg H; Soininen H; Karlsson IK; Alvarez I; Appollonio I; Giegling I; Skoog I; Saltvedt I; Rainero I; Rosas Allende I; Hort J; Diehl-Schmid J; Van Dongen J; Vidal J-S; Lehtisalo J; Wiltfang J; Thomassen JQ; Kornhuber J; Haines JL; Vogelgsang J; Pineda JA; Fortea J; Popp J; Deckert J; Buerger K; Morgan K; Fließbach K; Sleegers K; Molina-Porcel L; Kilander L; Weinhold L; Farrer LA; Wang L-S; Kleineidam L; Farotti L; Parnetti L; Tremolizzo L; Hausner L; Benussi L; Froelich L; Ikram MA; Deniz-Naranjo MC; Tsolaki M; Rosende-Roca M; Löwenmark M; Hulsman M; Spallazzi M; Pericak-Vance MA; Esiri M; Bernal Sánchez-Arjona M; Dalmasso MC; Martínez-Larrad MT; Arcaro M; Nöthen MM; Fernández-Fuertes M; Dichgans M; Ingelsson M; Herrmann MJ; Scherer M; Vyhnalek M; Kosmidis MH; Yannakoulia M; Schmid M; Ewers M; Heneka MT; Wagner M; Scamosci M; Kivipelto M; Hiltunen M; Zulaica M; Alegret M; Fornage M; Roberto N; van Schoor NM; Seidu NM; Banaj N; Armstrong NJ; Scarmeas N; Scherbaum N; Goldhardt O; Hanon O; Peters O; Skrobot OA; Quenez O; Lerch O; Bossù P; Caffarra P; Dionigi Rossi P; Sakka P; Mecocci P; Hoffmann P; Holmans PA; Fischer P; Riederer P; Yang Q; Marshall R; Kalaria RN; Mayeux R; Vandenberghe R; Cecchetti R; Ghidoni R; Frikke-Schmidt R; Sorbi S; Hägg S; Engelborghs S; Helisalmi S; Botne Sando S; Kern S; Archetti S; Boschi S; Fostinelli S; Gil S; Mendoza S; Mead S; Ciccone S; Djurovic S; Heilmann-Heimbach S; Riedel-Heller S; Kuulasmaa T; Del Ser T; Lebouvier T; Polak T; Ngandu T; Grimmer T; Bessi V; Escott-Price V; Giedraitis V; Deramecourt V; Maier W; Jian X; Pijnenburg YAL; EADB contributors; GR@ACE study group; DEGESCO consortium; IGAP (ADGC, CHARGE, EADI, GERAD); PGC-ALZ consortia; Kehoe PG; Garcia-Ribas G; Sánchez-Juan P; Pastor P; Pérez-Tur J; Piñol-Ripoll G; Lopez de Munain A; García-Alberca JM; Bullido MJ; Álvarez V; Lleó A; Real LM; Mir P; Medina M; Scheltens P; Holstege H; Marquié M; Sáez ME; Carracedo Á; Amouyel P; Schellenberg GD; Williams J; Seshadri S; van Duijn CM; Mather KA; Sánchez-Valle R; Serrano-Ríos M; Orellana A; Tárraga L; Blennow K; Huisman M; Andreassen OA; Posthuma D; Clarimón J; Boada M; van der Flier WM; Ramirez A; Lambert J-C; van der Lee SJ; Ruiz A
• Article: HUMAN GENETICS. 2021;140(6):849-861

  Deciphering the genetic and epidemiological landscape of mitochondrial DNA abundance.

  Hägg S; Jylhävä J; Wang Y; Czene K; Grassmann F
• Corrigendum: HUMAN GENETICS. 2021;140(6):863

  Correction to: Deciphering the genetic and epidemiological landscape of mitochondrial DNA abundance.

  Hägg S; Jylhävä J; Wang Y; Czene K; Grassmann F
• Article: MOLECULAR PSYCHIATRY. 2021;26(6):2148-2162

  DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan.

  van Dongen J; Hagenbeek FA; Suderman M; Roetman PJ; Sugden K; Chiocchetti AG; Ismail K; Mulder RH; Hafferty JD; Adams MJ; Walker RM; Morris SW; Lahti J; Küpers LK; Escaramis G; Alemany S; Jan Bonder M; Meijer M; Ip HF; Jansen R; Baselmans BML; Parmar P; Lowry E; Streit F; Sirignano L; Send TS; Frank J; Jylhävä J; Wang Y; Mishra PP; Colins OF; Corcoran DL; Poulton R; Mill J; Hannon E; Arseneault L; Korhonen T; Vuoksimaa E; Felix JF; Bakermans-Kranenburg MJ; Campbell A; Czamara D; Binder E; Corpeleijn E; Gonzalez JR; Grazuleviciene R; Gutzkow KB; Evandt J; Vafeiadi M; Klein M; van der Meer D; Ligthart L; BIOS Consortium; Kluft C; Davies GE; Hakulinen C; Keltikangas-Järvinen L; Franke B; Freitag CM; Konrad K; Hervas A; Fernández-Rivas A; Vetro A; Raitakari O; Lehtimäki T; Vermeiren R; Strandberg T; Räikkönen K; Snieder H; Witt SH; Deuschle M; Pedersen NL; Hägg S; Sunyer J; Franke L; Kaprio J; Ollikainen M; Moffitt TE; Tiemeier H; van IJzendoorn MH; Relton C; Vrijheid M; Sebert S; Jarvelin M-R; Caspi A; Evans KL; McIntosh AM; Bartels M; Boomsma DI
• Article: GEROSCIENCE. 2021;43(3):1519-1525

  Association between genetically predicted telomere length and facial skin aging in the UK Biobank: a Mendelian randomization study.

  Zhan Y; Hägg S
• Article: EPIGENOMICS. 2021;13(12):939-951

  Genome-wide associations between alcohol consumption and blood DNA methylation: evidence from twin study.

  Lu M; Xueying Q; Hexiang P; Wenjing G; Hägg S; Weihua C; Chunxiao L; Canqing Y; Jun L; Zengchang P; Liming C; Hua W; Xianping W; Yunzhang W; Liming L
• Review: ELIFE. 2021;10:e63425

  Sex differences in biological aging with a focus on human studies.

  Hägg S; Jylhävä J
• Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2021;69(5):1128-1139

  Frailty and comorbidity in predicting community COVID-19 mortality in the U.K. Biobank: The effect of sampling.

  Mak JKL; Kuja-Halkola R; Wang Y; Hägg S; Jylhävä J
• Article: CLINICAL EPIGENETICS. 2021;13(1):85

  Epigenome-wide association study of level and change in cognitive abilities from midlife through late life.

  Karlsson IK; Ericsson M; Wang Y; Jylhävä J; Hägg S; Dahl Aslan AK; Reynolds CA; Pedersen NL
• Preprint: BIORXIV. 2021

  A computational solution for bolstering reliability of epigenetic clocks: Implications for clinical trials and longitudinal tracking

  Higgins-Chen A; Thrush K; Wang Y; Kuo P-L; Wang M; Minteer C; Moore AZ; Bandinelli S; Vinkers C; Vermetten E; Rutten BPF; Geuze E; Okhuijsen-Pfeifer C; van der Horst M; Schreiter S; Gutwinski S; Luykx J; Ferrucci L; Crimmins E; Boks M; Hägg S; Hu-Seliger T; Levine M
• Article: EBIOMEDICINE. 2021;66:103318

  Clinical biomarkers and associations with healthspan and lifespan: Evidence from observational and genetic data.

  Li X; Ploner A; Wang Y; Zhan Y; Pedersen NL; Magnusson PK; Jylhävä J; Hägg S
• Preprint: RESEARCH SQUARE. 2021

  Epigenome-wide association study of level and change in cognitive abilities from midlife through late-life

  Karlsson I; Ericsson M; Wang Y; Jylhävä J; Hägg S; Aslan AD; Reynolds C; Pedersen N
• Preprint: MEDRXIV. 2021

  Genetic heterogeneity and subtypes of major depression

  Nguyen T-D; Harder A; Xiong Y; Kowalec K; Hägg S; Cai N; Kuja-Halkola R; Dalman C; Sullivan P; Lu Y
• Preprint: BIORXIV. 2021

  Within-sibship GWAS improve estimates of direct genetic effects

  Howe L; Nivard M; Morris T; Hansen A; Rasheed H; Cho Y; Chittoor G; Lind P; Palviainen T; van der Zee M; Cheesman R; Mangino M; Wang Y; Li S; Klaric L; Ratliff S; Bielak L; Nygaard M; Reynolds C; Balbona J; Bauer C; Boomsma D; Baras A; Campbell A; Campbell H; Chen Z; Christofidou P; Dahm C; Dokuru D; Evans L; de Geus EJC; Giddaluru S; Gordon S; Harden P; Havdahl A; Hill D; Kerr S; Kim Y; Kweon H; Latvala A; Li L; Lin K; Martikainen P; Magnusson PKE; Mills M; Lawlor D; Overton J; Pedersen N; Porteous D; Reid J; Silventoinen K; Southey M; Mallard T; Tucker-Drob E; Wright M; Hewitt J; Keller M; Stallings M; Christensen K; Kardia SLR; Peyser P; Smith J; Wilson J; Hopper J; Hägg S; Spector T; Pingault J-B; Plomin R; Bartels M; Martin N; Justice A; Millwood I; Hveem K; Naess Ø; Willer C; Åsvold BO; Koellinger P; Kaprio J; Medland S; Walters R; Benjamin D; Turley P; Evans D; Smith GD; Hayward C; Brumpton B; Hemani G; Davies N; Social Science Genetic Association Consortium; Within Family Consortium
• Article: MECHANISMS OF AGEING AND DEVELOPMENT. 2021;194:111426

  A geroscience approach for Parkinson's disease: Conceptual framework and design of PROPAG-AGEING project.

  Pirazzini C; Azevedo T; Baldelli L; Bartoletti-Stella A; Calandra-Buonaura G; Dal Molin A; Dimitri GM; Doykov I; Gómez-Garre P; Hägg S; Hällqvist J; Halsband C; Heywood W; Jesús S; Jylhävä J; Kwiatkowska KM; Labrador-Espinosa MA; Licari C; Maturo MG; Mengozzi G; Meoni G; Milazzo M; Periñán-Tocino MT; Ravaioli F; Sala C; Sambati L; Schade S; Schreglmann S; Spasov S; Tenori L; Williams D; Xumerle L; Zago E; Bhatia KP; Capellari S; Cortelli P; Garagnani P; Houlden H; Liò P; Luchinat C; Delledonne M; Mills K; Mir P; Mollenhauer B; Nardini C; Pedersen NL; Provini F; Strom S; Trenkwalder C; Turano P; Bacalini MG; Franceschi C; PROPAG-AGEING Consortium
• Editorial comment: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2021;49(1):29-32

  COVID-19: Opportunities for interdisciplinary research to improve care for older people in Sweden.

  Baxter R; Jemberie WB; Li X; Naseer M; Pauelsen M; Shebehe J; Viklund EWE; Xia X; Zulka LE; Badache A
• Article: FRONTIERS IN RESEARCH METRICS AND ANALYTICS. 2021;6:594424

  Gender Bias Impacts Top-Merited Candidates.

  Andersson ER; Hagberg CE; Hägg S
• Preprint: MEDRXIV. 2020

  Sex differences in genetic and environmental influences on frailty and its relation to body mass index and education

  Mak J; Reynolds C; Hägg S; Li X; Ericsson M; Pedersen N; Jylhävä J; Kuja-Halkola R
• Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2020;21(11):1555-1559.e2

  Age, Frailty, and Comorbidity as Prognostic Factors for Short-Term Outcomes in Patients With Coronavirus Disease 2019 in Geriatric Care.

  Hägg S; Jylhävä J; Wang Y; Xu H; Metzner C; Annetorp M; Garcia-Ptacek S; Khedri M; Boström A-M; Kadir A; Johansson A; Kivipelto M; Eriksdotter M; Cederholm T; Religa D
• Preprint: MEDRXIV. 2020

  Frailty and comorbidity in predicting community COVID-19 mortality in the UK Biobank: the effect of sampling

  Mak J; Kuja-Halkola R; Wang Y; Hägg S; Jylhävä J
• Article: LIFE SCIENCE ALLIANCE. 2020;3(10):e202000817

  Profiles of histidine-rich glycoprotein associate with age and risk of all-cause mortality.

  Hong M-G; Dodig-Crnković T; Chen X; Drobin K; Lee W; Wang Y; Edfors F; Kotol D; Thomas CE; Sjöberg R; Odeberg J; Hamsten A; Silveira A; Hall P; Nilsson P; Pawitan Y; Uhlén M; Pedersen NL; Hägg S; Magnusson PK; Schwenk JM
• Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2020;75(10):1943-1950

  Drivers of Frailty from Adulthood into Old Age: Results from a 27-Year Longitudinal Population-Based Study in Sweden.

  Raymond E; Reynolds CA; Dahl Aslan AK; Finkel D; Ericsson M; Hägg S; Pedersen NL; Jylhävä J
• Preprint: BIORXIV. 2020

  Deciphering the genetic and epidemiological landscape of mitochondrial DNA abundance

  Hägg S; Jylhävä J; Wang Y; Czene K; Grassmann F
• Article: JOURNAL OF INTERNAL MEDICINE. 2020;288(2):234-247

  Joint impact of common risk factors on incident dementia: A cohort study of the Swedish Twin Registry.

  Tomata Y; Li X; Karlsson IK; Mosing MA; Pedersen NL; Hägg S
• Article: AGING CELL. 2020;19(8):e13197

  A decade of epigenetic change in aging twins: Genetic and environmental contributions to longitudinal DNA methylation.

  Reynolds CA; Tan Q; Munoz E; Jylhävä J; Hjelmborg J; Christiansen L; Hägg S; Pedersen NL
• Preprint: BIORXIV. 2020

  DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan

  van Dongen J; Hagenbeek F; Suderman M; Roetman P; Sugden K; Chiocchetti A; Ismail K; Mulder R; Hafferty J; Adams M; Walker R; Morris S; Lahti J; Küpers L; Escaramis G; Alemany S; Bonder MJ; Meijer M; Ip H; Jansen R; Baselmans B; Parmar P; Lowry E; Streit F; Sirignano L; Send T; Frank J; Jylhävä J; Wang Y; Mishra PP; Colins O; Corcoran D; Poulton R; Mill J; Hannon E; Arseneault L; Korhonen T; Vuoksimaa E; Felix J; Bakermans-Kranenburg M; Campbell A; Czamara D; Binder E; Corpeleijn E; González JR; Grazuleviciene R; Gutzkow K; Evandt J; Vafeiadi M; Klein M; van der Meer D; Ligthart L; Kluft C; Davies G; Hakulinen C; Keltikangas-Järvinen L; Franke B; Freitag C; Konrad K; Hervas A; Fernández-Rivas A; Vetro A; Raitakari O; Lehtimäki T; Vermeiren R; Strandberg T; Räikkönen K; Snieder H; Witt S; Deuschle M; Pedersen N; Hägg S; Sunyer J; Franke L; Kaprio J; Ollikainen M; Moffitt T; Tiemeier H; van Ijzendoorn M; Relton C; Vrijheid M; Sebert S; Jarvelin M-R; Caspi A; Evans K; McIntosh A; Bartels M; Boomsma D; BIOS Consortium
• Article: PSYCHOSOMATIC MEDICINE. 2020;82(6):614-622

  The Association of Individual Changes in Stressful Life Events and Telomere Length Over Time in Twins 50 Years and Older.

  Gerritsen L; Hägg S; Reynolds CA; Pedersen NL
• Preprint: BIORXIV. 2020

  Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing

  McCartney D; Min J; Richmond R; Lu A; Sobczyk M; Davies G; Broer L; Guo X; Jeong A; Jung J; Kasela S; Katrinli S; Kuo P-L; Matias-Garcia P; Mishra P; Nygaard M; Palviainen T; Patki A; Raffield L; Ratliff S; Richardson T; Robinson O; Soerensen M; Sun D; Tsai P-C; van der Zee M; Walker R; Wang X; Wang Y; Xia R; Xu Z; Yao J; Zhao W; Correa A; Boerwinkle E; Dugué P-A; Durda P; Elliott H; Gieger C; de Geus EJC; Harris S; Hemani G; Imboden M; Kähönen M; Kardia SLR; Kresovich J; Li S; Lunetta K; Mangino M; Mason D; McIntosh A; Mengel-From J; Moore AZ; Murabito J; Ollikainen M; Pankow J; Pedersen N; Peters A; Polidoro S; Porteous D; Raitakari O; Rich S; Sandler D; Sillanpää E; Smith A; Southey M; Strauch K; Tiwari H; Tanaka T; Tillin T; Uitterlinden A; Van Den Berg D; van Dongen J; Wilson J; Wright J; Yet I; Arnett D; Bandinelli S; Bell J; Binder A; Boomsma D; Chen W; Christensen K; Conneely K; Elliott P; Ferrucci L; Fornage M; Hägg S; Hayward C; Irvin M; Kaprio J; Lawlor D; Lehtimäki T; Lohoff F; Milani L; Milne R; Probst-Hensch N; Reiner A; Ritz B; Rotter J; Smith J; Taylor J; van Meurs JBJ; Vineis P; Waldenberger M; Deary I; Relton C; Horvath S; Marioni R; The Genetics of DNA Methylation Consortium; NHLBI Trans-Omics for Precision Medicine (TOPMed)
• Article: INTERNATIONAL JOURNAL OF OBESITY. 2020;44(6):1397-1405

  Replicating associations between DNA methylation and body mass index in a longitudinal sample of older twins.

  Karlsson IK; Ericsson M; Wang Y; Jylhävä J; Hägg S; Pedersen NL; Reynolds CA; Dahl Aslan AK
• Article: EUROPEAN JOURNAL OF NUTRITION. 2020;59(4):1763-1766

  Polyunsaturated fatty acids and risk of Alzheimer's disease: a Mendelian randomization study.

  Tomata Y; Larsson SC; Hägg S
• Article: BIOLOGICAL PSYCHIATRY. 2020;87(8):708-716

  Childhood Adoption and Mental Health in Adulthood: The Role of Gene-Environment Correlations and Interactions in the UK Biobank.

  Lehto K; Hägg S; Lu D; Karlsson R; Pedersen NL; Mosing MA
• Article: CLINICAL EPIGENETICS. 2020;12(1):49

  DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936.

  Seeboth A; McCartney DL; Wang Y; Hillary RF; Stevenson AJ; Walker RM; Campbell A; Evans KL; McIntosh AM; Hägg S; Deary IJ; Marioni RE
• Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2020;106(3):389-404

  Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length.

  Li C; Stoma S; Lotta LA; Warner S; Albrecht E; Allione A; Arp PP; Broer L; Buxton JL; Da Silva Couto Alves A; Deelen J; Fedko IO; Gordon SD; Jiang T; Karlsson R; Kerrison N; Loe TK; Mangino M; Milaneschi Y; Miraglio B; Pervjakova N; Russo A; Surakka I; van der Spek A; Verhoeven JE; Amin N; Beekman M; Blakemore AI; Canzian F; Hamby SE; Hottenga J-J; Jones PD; Jousilahti P; Mägi R; Medland SE; Montgomery GW; Nyholt DR; Perola M; Pietiläinen KH; Salomaa V; Sillanpää E; Suchiman HE; van Heemst D; Willemsen G; Agudo A; Boeing H; Boomsma DI; Chirlaque M-D; Fagherazzi G; Ferrari P; Franks P; Gieger C; Eriksson JG; Gunter M; Hägg S; Hovatta I; Imaz L; Kaprio J; Kaaks R; Key T; Krogh V; Martin NG; Melander O; Metspalu A; Moreno C; Onland-Moret NC; Nilsson P; Ong KK; Overvad K; Palli D; Panico S; Pedersen NL; Penninx BWJH; Quirós JR; Jarvelin MR; Rodríguez-Barranco M; Scott RA; Severi G; Slagboom PE; Spector TD; Tjonneland A; Trichopoulou A; Tumino R; Uitterlinden AG; van der Schouw YT; van Duijn CM; Weiderpass E; Denchi EL; Matullo G; Butterworth AS; Danesh J; Samani NJ; Wareham NJ; Nelson CP; Langenberg C; Codd V
• Corrigendum: NATURE GENETICS. 2020;52(3):354

  Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.

  Jansen IE; Savage JE; Watanabe K; Bryois J; Williams DM; Steinberg S; Sealock J; Karlsson IK; Hägg S; Athanasiu L; Voyle N; Proitsi P; Witoelar A; Stringer S; Aarsland D; Almdahl IS; Andersen F; Bergh S; Bettella F; Bjornsson S; Brækhus A; Bråthen G; de Leeuw C; Desikan RS; Djurovic S; Dumitrescu L; Fladby T; Hohman TJ; Jonsson PV; Kiddle SJ; Rongve A; Saltvedt I; Sando SB; Selbæk G; Shoai M; Skene NG; Snaedal J; Stordal E; Ulstein ID; Wang Y; White LR; Hardy J; Hjerling-Leffler J; Sullivan PF; van der Flier WM; Dobson R; Davis LK; Stefansson H; Stefansson K; Pedersen NL; Ripke S; Andreassen OA; Posthuma D
• Article: EJSO. 2020;46(3):316-320

  Should we invest in biological age predictors to treat colorectal cancer in older adults?

  Hägg S; Jylhävä J
• Article: ELIFE. 2020;9:e51507

  Longitudinal trajectories, correlations and mortality associations of nine biological ages across 20-years follow-up.

  Li X; Ploner A; Wang Y; Magnusson PK; Reynolds C; Finkel D; Pedersen NL; Jylhävä J; Hägg S
• Article: HEART. 2020;106(4):267-272

  Marital status, telomere length and cardiovascular disease risk in a Swedish prospective cohort.

  Chen R; Zhan Y; Pedersen N; Fall K; Valdimarsdóttir UA; Hägg S; Fang F
• Conference publication: BEHAVIOR GENETICS. 2020;50(6):485-487

  DNA methylation signatures of a broad spectrum of aggressive behavior: a meta-analysis of epigenome-wide studies across the lifespan

  van Dongen J; Hagenbeek FA; Suderman M; Roetman P; Sugden K; Chiocchetti AG; Ismail K; Mulder RH; Hafferty J; Adams MJ; Walker RM; Morris SW; Lahti J; Kupers LK; Escaramis G; Alemany S; Bonder MJ; Meijer M; Ip HF; Jansen R; Baselmans BML; Parmar P; Lowry E; Streit F; Sirignano L; Send T; Frank J; Jylhava J; Wang Y; Mishra PP; Colins OF; Corcoran D; Poulton R; Mill J; Hannon EJ; Arseneault L; Korhonen T; Vuoksimaa E; Felix J; Bakermans-Kranenburg M; Campbell A; Czamara D; Binder E; Corpeleijn E; Ramon Gonzalez J; Grazuleviciene R; Gutzkow KB; Evandt J; Vafeiadi M; Klein M; van der Meer D; Ligthart L; Kluft C; Davies GE; Hakulinen C; Keltikangas-Jarvinen L; Franke B; Freitag CM; Konrad K; Hervas A; Fernandez-Rivas A; Vetro A; Raitakari O; Lehtimaki T; Vermeiren R; Strandberg T; Raikkonen K; Snieder H; Witt SH; Deuschle M; Pedersen NL; Hagg S; Sunyer J; Franke L; Kaprio J; Ollikainen M; Moffitt TE; Tiemeier H; van Ijzendoorn MH; Relton C; Vrijheid M; Sebert S; Jarvelin M-R; Caspi A; Evans KL; McIntosh AM; Bartels M; Boomsma D
• Article: CLINICAL EPIGENETICS. 2019;11(1):187

  Comprehensive longitudinal study of epigenetic mutations in aging.

  Wang Y; Karlsson R; Jylhävä J; Hedman ÅK; Almqvist C; Karlsson IK; Pedersen NL; Almgren M; Hägg S
• Preprint: BIORXIV. 2019

  Implicit bias is strongest when assessing top candidates

  Andersson E; Hagberg C; Hägg S
• Preprint: MEDRXIV. 2019

  Drivers of Frailty from Adulthood into Old Age: Results from a 27-year Longitudinal Population-Based Study in Sweden

  Raymond E; Reynolds C; Dahl Aslan A; Finkel D; Ericsson M; Hägg S; Pedersen N; Jylhävä J
• Journal article: INNOVATION IN AGING. 2019;3(Supplement_1):s33

  LONGITUDINAL TRAJECTORIES OF EPIGENETIC CLOCKS IN HUMANS AND EFFECTS OF MEDICATION USE

  Hagg S
• Journal article: INNOVATION IN AGING. 2019;3(Supplement_1):s32-s33

  DNA METHYLATION: CAUSE OR CONSEQUENCE OF AGING?

  Levine ME; Hagg S
• Preprint: MEDRXIV. 2019

  DNA methylation outlier burden, health and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936

  Seeboth A; McCartney D; Wang Y; Hillary R; Stevenson A; Walker R; Evans K; McIntosh A; Hägg S; Deary I; Marioni R
• Article: PSYCHOSOMATIC MEDICINE. 2019;81(9):799-807

  Neuroticism as a Predictor of Frailty in Old Age: A Genetically Informative Approach.

  Daníelsdóttir HB; Jylhävä J; Hägg S; Lu Y; Colodro-Conde L; Martin NG; Pedersen NL; Mosing MA; Lehto K
• Article: EPIGENETICS. 2019;14(10):961-976

  Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts.

  Sturm G; Cardenas A; Bind M-A; Horvath S; Wang S; Wang Y; Hägg S; Hirano M; Picard M
• Preprint: BIORXIV. 2019

  A decade of epigenetic change in aging twins: genetic and environmental contributions to longitudinal DNA methylation

  Reynolds C; Tan Q; Munoz E; Jylhävä J; Hjelmborg J; Christiansen L; Hägg S; Pedersen N
• Preprint: MEDRXIV. 2019

  A Genome-Wide Association Study of the Frailty Index Highlights Synaptic Pathways in Aging

  Atkins J; Jylhävä J; Pedersen N; Magnusson P; Lu Y; Wang Y; Hägg S; Melzer D; Williams D; Pilling L
• Preprint: BIORXIV. 2019

  Comprehensive longitudinal study of epigenetic mutations in aging

  Wang Y; Karlsson R; Jylhävä J; Hedman Å; Almqvist C; Karlsson I; Pedersen N; Almgren M; Hägg S
• Article: EMERGING TOPICS IN LIFE SCIENCES. 2019;3(4):411-421

  Developments in molecular epidemiology of aging.

  Hägg S; Belsky DW; Cohen AA
• Article: BMJ OPEN. 2019;9(7):e026192

  Short-term and long-term case-fatality rates for myocardial infarction and ischaemic stroke by socioeconomic position and sex: a population-based cohort study in Sweden, 1990-1994 and 2005-2009.

  Malki N; Hägg S; Tiikkaja S; Koupil I; Sparén P; Ploner A
• Article: EBIOMEDICINE. 2019;45:487-494

  Genetically-predicted life-long lowering of low-density lipoprotein cholesterol is associated with decreased frailty: A Mendelian randomization study in UK biobank.

  Wang Q; Wang Y; Lehto K; Pedersen NL; Williams DM; Hägg S
• Article: ROYAL SOCIETY OPEN SCIENCE. 2019;6(6):190420

  Smoking does not accelerate leucocyte telomere attrition: a meta-analysis of 18 longitudinal cohorts.

  Bateson M; Aviv A; Bendix L; Benetos A; Ben-Shlomo Y; Bojesen SE; Cooper C; Cooper R; Deary IJ; Hägg S; Harris SE; Kark JD; Kronenberg F; Kuh D; Labat C; Martin-Ruiz CM; Meyer C; Nordestgaard BG; Penninx BWJH; Pepper GV; Révész D; Said MA; Starr JM; Syddall H; Thomson WM; van der Harst P; Whooley M; von Zglinicki T; Willeit P; Zhan Y; Nettle D
• Article: BIOGERONTOLOGY. 2019;20(3):321-329

  Can markers of biological age predict dependency in old age?

  Jylhävä J; Jiang M; Foebel AD; Pedersen NL; Hägg S
• Article: BMC MEDICINE. 2019;17(1):94

  The frailty index is a predictor of cause-specific mortality independent of familial effects from midlife onwards: a large cohort study.

  Li X; Ploner A; Karlsson IK; Liu X; Magnusson PKE; Pedersen NL; Hägg S; Jylhävä J
• Corrigendum: NATURE COMMUNICATIONS. 2019;10(1):2068

  Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

  Davies G; Lam M; Harris SE; Trampush JW; Luciano M; Hill WD; Hagenaars SP; Ritchie SJ; Marioni RE; Fawns-Ritchie C; Liewald DCM; Okely JA; Ahola-Olli AV; Barnes CLK; Bertram L; Bis JC; Burdick KE; Christoforou A; DeRosse P; Djurovic S; Espeseth T; Giakoumaki S; Giddaluru S; Gustavson DE; Hayward C; Hofer E; Ikram MA; Karlsson R; Knowles E; Lahti J; Leber M; Li S; Mather KA; Melle I; Morris D; Oldmeadow C; Palviainen T; Payton A; Pazoki R; Petrovic K; Reynolds CA; Sargurupremraj M; Scholz M; Smith JA; Smith AV; Terzikhan N; Thalamuthu A; Trompet S; van der Lee SJ; Ware EB; Windham BG; Wright MJ; Yang J; Yu J; Ames D; Amin N; Amouyel P; Andreassen OA; Armstrong NJ; Assareh AA; Attia JR; Attix D; Avramopoulos D; Bennett DA; Böhmer AC; Boyle PA; Brodaty H; Campbell H; Cannon TD; Cirulli ET; Congdon E; Conley ED; Corley J; Cox SR; Dale AM; Dehghan A; Dick D; Dickinson D; Eriksson JG; Evangelou E; Faul JD; Ford I; Freimer NA; Gao H; Giegling I; Gillespie NA; Gordon SD; Gottesman RF; Griswold ME; Gudnason V; Harris TB; Hartmann AM; Hatzimanolis A; Heiss G; Holliday EG; Joshi PK; Kähönen M; Kardia SLR; Karlsson I; Kleineidam L; Knopman DS; Kochan NA; Konte B; Kwok JB; Le Hellard S; Lee T; Lehtimäki T; Li S-C; Lill CM; Liu T; Koini M; London E; Longstreth WT; Lopez OL; Loukola A; Luck T; Lundervold AJ; Lundquist A; Lyytikäinen L-P; Martin NG; Montgomery GW; Murray AD; Need AC; Noordam R; Nyberg L; Ollier W; Papenberg G; Pattie A; Polasek O; Poldrack RA; Psaty BM; Reppermund S; Riedel-Heller SG; Rose RJ; Rotter JI; Roussos P; Rovio SP; Saba Y; Sabb FW; Sachdev PS; Satizabal CL; Schmid M; Scott RJ; Scult MA; Simino J; Slagboom PE; Smyrnis N; Soumaré A; Stefanis NC; Stott DJ; Straub RE; Sundet K; Taylor AM; Taylor KD; Tzoulaki I; Tzourio C; Uitterlinden A; Vitart V; Voineskos AN; Kaprio J; Wagner M; Wagner H; Weinhold L; Wen KH; Widen E; Yang Q; Zhao W; Adams HHH; Arking DE; Bilder RM; Bitsios P; Boerwinkle E; Chiba-Falek O; Corvin A; De Jager PL; Debette S; Donohoe G; Elliott P; Fitzpatrick AL; Gill M; Glahn DC; Hägg S; Hansell NK; Hariri AR; Ikram MK; Jukema JW; Vuoksimaa E; Keller MC; Kremen WS; Launer L; Lindenberger U; Palotie A; Pedersen NL; Pendleton N; Porteous DJ; Räikkönen K; Raitakari OT; Ramirez A; Reinvang I; Rudan I; Dan Rujescu; Schmidt R; Schmidt H; Schofield PW; Schofield PR; Starr JM; Steen VM; Trollor JN; Turner ST; Van Duijn CM; Villringer A; Weinberger DR; Weir DR; Wilson JF; Malhotra A; McIntosh AM; Gale CR; Seshadri S; Mosley TH; Bressler J; Lencz T; Deary IJ
• Review: CURRENT OPINION IN CARDIOLOGY. 2019;34(3):270-274

  Telomere length and cardiovascular disease risk.

  Zhan Y; Hägg S
• Preprint: BIORXIV. 2019

  Human Aging DNA Methylation Signatures are Conserved but Accelerated in Cultured Fibroblasts

  Sturm G; Cardenas A; Bind M-A; Horvath S; Wang S; Wang Y; Hägg S; Hirano M; Picard M
• Preprint: BIORXIV. 2019

  Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases

  Brumpton B; Sanderson E; Hartwig FP; Harrison S; Vie GÅ; Cho Y; Howe L; Hughes A; Boomsma D; Havdahl A; Hopper J; Neale M; Nivard M; Pedersen N; Reynolds C; Tucker-Drob E; Grotzinger A; Howe L; Morris T; Li S; Chen W-M; Bjørngaard JH; Hveem K; Willer C; Evans D; Kaprio J; Åsvol BO; Smith GD; Åsvold BO; Hemani G; Davies N; MR within-family Consortium
• Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2019;74(4):582-587

  A Frailty Index for UK Biobank Participants.

  Williams DM; Jylhävä J; Pedersen NL; Hägg S
• Article: NATURE GENETICS. 2019;51(3):404-413

  Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.

  Jansen IE; Savage JE; Watanabe K; Bryois J; Williams DM; Steinberg S; Sealock J; Karlsson IK; Hägg S; Athanasiu L; Voyle N; Proitsi P; Witoelar A; Stringer S; Aarsland D; Almdahl IS; Andersen F; Bergh S; Bettella F; Bjornsson S; Brækhus A; Bråthen G; de Leeuw C; Desikan RS; Djurovic S; Dumitrescu L; Fladby T; Hohman TJ; Jonsson PV; Kiddle SJ; Rongve A; Saltvedt I; Sando SB; Selbæk G; Shoai M; Skene NG; Snaedal J; Stordal E; Ulstein ID; Wang Y; White LR; Hardy J; Hjerling-Leffler J; Sullivan PF; van der Flier WM; Dobson R; Davis LK; Stefansson H; Stefansson K; Pedersen NL; Ripke S; Andreassen OA; Posthuma D
• Article: EBIOMEDICINE. 2019;40:710-716

  Longitudinal changes in the genetic and environmental influences on the epigenetic clocks across old age: Evidence from two twin cohorts.

  Jylhävä J; Hjelmborg J; Soerensen M; Munoz E; Tan Q; Kuja-Halkola R; Mengel-From J; Christensen K; Christiansen L; Hägg S; Pedersen NL; Reynolds CA
• Preprint: BIORXIV. 2019

  Neuroticism as a predictor of frailty in old age: a genetically informative approach

  Danielsdottir HB; Jylhävä J; Hägg S; Lu Y; Colodro-Conde L; Martin N; Pedersen N; Mosing M; Lehto K
• Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2019;74(1):57-61

  Tracking the Epigenetic Clock Across the Human Life Course: A Meta-analysis of Longitudinal Cohort Data.

  Marioni RE; Suderman M; Chen BH; Horvath S; Bandinelli S; Morris T; Beck S; Ferrucci L; Pedersen NL; Relton CL; Deary IJ; Hägg S
• Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S218-S219

  Early and late-life stress and longitudinal telomere length in old twins

  Gerritsen L; Hagg S; Reynolds C; Pedersen N
• Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:1114

  CHILDHOOD ADOPTION AND MENTAL HEALTH IN ADULTHOOD: GENE-ENVIRONMENT INTERPLAY AND CROSS-TRAIT GENETIC OVERLAP WITH AFFECTIVE TRAITS IN UK BIOBANK

  Lehto K; Hagg S; Karlsson R; Pedersen NL; Mosing MA
• Conference publication: BEHAVIOR GENETICS. 2019;49(6):532

  Loneliness and DNA methylation of variants in the conserved transcriptional response to adversity (CTRA) pathway

  Phillips D; Wang Y; Pedersen NL; Hagg S; Reynolds C
• Conference publication: BEHAVIOR GENETICS. 2019;49(6):527

  10-year epigenetic change: age-associated CpGs are differentially heritable

  Reynolds C; Tan Q; Munoz E; Jylhava J; Hjelmborg J; Christiansen L; Hagg S; Pedersen NL
• Conference publication: BEHAVIOR GENETICS. 2019;49(6):515

  Neuroticism as a predictor of frailty in old age: a genetically informative approach

  Bjork H; Jylhava J; Hagg S; Lu Y; Colodro-Conde L; Martin N; Pedersen NL; Mosing M; Lehto K
• Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2019;109(1):90-98

  Circulating antioxidants and Alzheimer disease prevention: a Mendelian randomization study.

  Williams DM; Hägg S; Pedersen NL
• Conference publication: BEHAVIOR GENETICS. 2019;49(6):503

  DNA methylation and change in late-life cognitive abilities

  Karlsson I; Ericsson M; Wang Y; Jylhava J; Hagg S; Aslan AD; Reynolds C; Pedersen NL
• Conference publication: BEHAVIOR GENETICS. 2019;49(6):508-509

  Childhood adoption and mental health in adulthood: the role of genetic confounding

  Lehto K; Hagg S; Lu D; Karlsson R; Pedersen NL; Mosing M
• Preprint: BIORXIV. 2018

  The frailty index is a predictor of cause-specific mortality independent of familial effects from midlife onwards

  Li X; Ploner A; Karlsson I; Liu X; Magnusson PKE; Pedersen N; Hägg S; Jylhävä J
• Article: NATURE COMMUNICATIONS. 2018;9(1):5141

  GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.

  Franceschini N; Giambartolomei C; de Vries PS; Finan C; Bis JC; Huntley RP; Lovering RC; Tajuddin SM; Winkler TW; Graff M; Kavousi M; Dale C; Smith AV; Hofer E; van Leeuwen EM; Nolte IM; Lu L; Scholz M; Sargurupremraj M; Pitkänen N; Franzén O; Joshi PK; Noordam R; Marioni RE; Hwang S-J; Musani SK; Schminke U; Palmas W; Isaacs A; Correa A; Zonderman AB; Hofman A; Teumer A; Cox AJ; Uitterlinden AG; Wong A; Smit AJ; Newman AB; Britton A; Ruusalepp A; Sennblad B; Hedblad B; Pasaniuc B; Penninx BW; Langefeld CD; Wassel CL; Tzourio C; Fava C; Baldassarre D; O'Leary DH; Teupser D; Kuh D; Tremoli E; Mannarino E; Grossi E; Boerwinkle E; Schadt EE; Ingelsson E; Veglia F; Rivadeneira F; Beutner F; Chauhan G; Heiss G; Snieder H; Campbell H; Völzke H; Markus HS; Deary IJ; Jukema JW; de Graaf J; Price J; Pott J; Hopewell JC; Liang J; Thiery J; Engmann J; Gertow K; Rice K; Taylor KD; Dhana K; Kiemeney LALM; Lind L; Raffield LM; Launer LJ; Holdt LM; Dörr M; Dichgans M; Traylor M; Sitzer M; Kumari M; Kivimaki M; Nalls MA; Melander O; Raitakari O; Franco OH; Rueda-Ochoa OL; Roussos P; Whincup PH; Amouyel P; Giral P; Anugu P; Wong Q; Malik R; Rauramaa R; Burkhardt R; Hardy R; Schmidt R; de Mutsert R; Morris RW; Strawbridge RJ; Wannamethee SG; Hägg S; Shah S; McLachlan S; Trompet S; Seshadri S; Kurl S; Heckbert SR; Ring S; Harris TB; Lehtimäki T; Galesloot TE; Shah T; de Faire U; Plagnol V; Rosamond WD; Post W; Zhu X; Zhang X; Guo X; Saba Y; MEGASTROKE Consortium; Dehghan A; Seldenrijk A; Morrison AC; Hamsten A; Psaty BM; van Duijn CM; Lawlor DA; Mook-Kanamori DO; Bowden DW; Schmidt H; Wilson JF; Wilson JG; Rotter JI; Wardlaw JM; Deanfield J; Halcox J; Lyytikäinen L-P; Loeffler M; Evans MK; Debette S; Humphries SE; Völker U; Gudnason V; Hingorani AD; Björkegren JLM; Casas JP; O'Donnell CJ
• Review: AGEING RESEARCH REVIEWS. 2018;48:11-20

  Telomere Length and All-Cause Mortality: A Meta-analysis.

  Wang Q; Zhan Y; Pedersen NL; Fang F; Hägg S
• Preprint: BIORXIV. 2018

  Profiles of circulating histidine-rich glycoprotein associate with chronological age and risk of all-cause mortality

  Hong M-G; Dodig-Crnković T; Chen X; Drobin K; Lee W; Wang Y; Edfors F; Kotol D; Thomas CE; Sjöberg R; Odeberg J; Hamsten A; Silveira A; Hall P; Nilsson P; Pawitan Y; Hägg S; Uhlén M; Pedersen N; Magnusson P; Schwenk J
• Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2018;187(10):2186-2191

  Leukocyte Telomere Length and All-Cause Mortality: A Between-Within Twin Study With Time-Dependent Effects Using Generalized Survival Models.

  Zhan Y; Liu X-R; Reynolds CA; Pedersen NL; Hägg S; Clements MS
• Article: EPIGENETICS. 2018;13(9):975-987

  Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins.

  Wang Y; Karlsson R; Lampa E; Zhang Q; Hedman ÅK; Almgren M; Almqvist C; McRae AF; Marioni RE; Ingelsson E; Visscher PM; Deary IJ; Lind L; Morris T; Beck S; Pedersen NL; Hägg S
• Article: NEUROBIOLOGY OF AGING. 2018;69:111-116

  Association of telomere length with general cognitive trajectories: a meta-analysis of four prospective cohort studies.

  Zhan Y; Clements MS; Roberts RO; Vassilaki M; Druliner BR; Boardman LA; Petersen RC; Reynolds CA; Pedersen NL; Hägg S
• Article: EPIGENETICS. 2018;13(8):866-874

  Implementing a method for studying longitudinal DNA methylation variability in association with age.

  Wang Y; Pedersen NL; Hägg S
• Article: NATURE GENETICS. 2018;50(7):912-919

  Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

  Savage JE; Jansen PR; Stringer S; Watanabe K; Bryois J; de Leeuw CA; Nagel M; Awasthi S; Barr PB; Coleman JRI; Grasby KL; Hammerschlag AR; Kaminski JA; Karlsson R; Krapohl E; Lam M; Nygaard M; Reynolds CA; Trampush JW; Young H; Zabaneh D; Hägg S; Hansell NK; Karlsson IK; Linnarsson S; Montgomery GW; Muñoz-Manchado AB; Quinlan EB; Schumann G; Skene NG; Webb BT; White T; Arking DE; Avramopoulos D; Bilder RM; Bitsios P; Burdick KE; Cannon TD; Chiba-Falek O; Christoforou A; Cirulli ET; Congdon E; Corvin A; Davies G; Deary IJ; DeRosse P; Dickinson D; Djurovic S; Donohoe G; Conley ED; Eriksson JG; Espeseth T; Freimer NA; Giakoumaki S; Giegling I; Gill M; Glahn DC; Hariri AR; Hatzimanolis A; Keller MC; Knowles E; Koltai D; Konte B; Lahti J; Le Hellard S; Lencz T; Liewald DC; London E; Lundervold AJ; Malhotra AK; Melle I; Morris D; Need AC; Ollier W; Palotie A; Payton A; Pendleton N; Poldrack RA; Räikkönen K; Reinvang I; Roussos P; Rujescu D; Sabb FW; Scult MA; Smeland OB; Smyrnis N; Starr JM; Steen VM; Stefanis NC; Straub RE; Sundet K; Tiemeier H; Voineskos AN; Weinberger DR; Widen E; Yu J; Abecasis G; Andreassen OA; Breen G; Christiansen L; Debrabant B; Dick DM; Heinz A; Hjerling-Leffler J; Ikram MA; Kendler KS; Martin NG; Medland SE; Pedersen NL; Plomin R; Polderman TJC; Ripke S; van der Sluis S; Sullivan PF; Vrieze SI; Wright MJ; Posthuma D
• Journal article: REVUE D EPIDEMIOLOGIE ET DE SANTE PUBLIQUE. 2018;66:s237

  Circulating antioxidants and Alzheimer's disease prevention: A Mendelian randomization study

  Williams D; Hägg S; Pedersen N
• Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2018;47(3):899-907

  Apolipoprotein E DNA methylation and late-life disease.

  Karlsson IK; Ploner A; Wang Y; Gatz M; Pedersen NL; Hägg S
• Article: NATURE COMMUNICATIONS. 2018;9(1):2098

  Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

  Davies G; Lam M; Harris SE; Trampush JW; Luciano M; Hill WD; Hagenaars SP; Ritchie SJ; Marioni RE; Fawns-Ritchie C; Liewald DCM; Okely JA; Ahola-Olli AV; Barnes CLK; Bertram L; Bis JC; Burdick KE; Christoforou A; DeRosse P; Djurovic S; Espeseth T; Giakoumaki S; Giddaluru S; Gustavson DE; Hayward C; Hofer E; Ikram MA; Karlsson R; Knowles E; Lahti J; Leber M; Li S; Mather KA; Melle I; Morris D; Oldmeadow C; Palviainen T; Payton A; Pazoki R; Petrovic K; Reynolds CA; Sargurupremraj M; Scholz M; Smith JA; Smith AV; Terzikhan N; Thalamuthu A; Trompet S; van der Lee SJ; Ware EB; Windham BG; Wright MJ; Yang J; Yu J; Ames D; Amin N; Amouyel P; Andreassen OA; Armstrong NJ; Assareh AA; Attia JR; Attix D; Avramopoulos D; Bennett DA; Böhmer AC; Boyle PA; Brodaty H; Campbell H; Cannon TD; Cirulli ET; Congdon E; Conley ED; Corley J; Cox SR; Dale AM; Dehghan A; Dick D; Dickinson D; Eriksson JG; Evangelou E; Faul JD; Ford I; Freimer NA; Gao H; Giegling I; Gillespie NA; Gordon SD; Gottesman RF; Griswold ME; Gudnason V; Harris TB; Hartmann AM; Hatzimanolis A; Heiss G; Holliday EG; Joshi PK; Kähönen M; Kardia SLR; Karlsson I; Kleineidam L; Knopman DS; Kochan NA; Konte B; Kwok JB; Le Hellard S; Lee T; Lehtimäki T; Li S-C; Lill CM; Liu T; Koini M; London E; Longstreth WT; Lopez OL; Loukola A; Luck T; Lundervold AJ; Lundquist A; Lyytikäinen L-P; Martin NG; Montgomery GW; Murray AD; Need AC; Noordam R; Nyberg L; Ollier W; Papenberg G; Pattie A; Polasek O; Poldrack RA; Psaty BM; Reppermund S; Riedel-Heller SG; Rose RJ; Rotter JI; Roussos P; Rovio SP; Saba Y; Sabb FW; Sachdev PS; Satizabal CL; Schmid M; Scott RJ; Scult MA; Simino J; Slagboom PE; Smyrnis N; Soumaré A; Stefanis NC; Stott DJ; Straub RE; Sundet K; Taylor AM; Taylor KD; Tzoulaki I; Tzourio C; Uitterlinden A; Vitart V; Voineskos AN; Kaprio J; Wagner M; Wagner H; Weinhold L; Wen KH; Widen E; Yang Q; Zhao W; Adams HHH; Arking DE; Bilder RM; Bitsios P; Boerwinkle E; Chiba-Falek O; Corvin A; De Jager PL; Debette S; Donohoe G; Elliott P; Fitzpatrick AL; Gill M; Glahn DC; Hägg S; Hansell NK; Hariri AR; Ikram MK; Jukema JW; Vuoksimaa E; Keller MC; Kremen WS; Launer L; Lindenberger U; Palotie A; Pedersen NL; Pendleton N; Porteous DJ; Räikkönen K; Raitakari OT; Ramirez A; Reinvang I; Rudan I; Dan Rujescu; Schmidt R; Schmidt H; Schofield PW; Schofield PR; Starr JM; Steen VM; Trollor JN; Turner ST; Van Duijn CM; Villringer A; Weinberger DR; Weir DR; Wilson JF; Malhotra A; McIntosh AM; Gale CR; Seshadri S; Mosley TH; Bressler J; Lencz T; Deary IJ
• Article: HUMAN MOLECULAR GENETICS. 2018;27(10):1809-1818

  A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia.

  Chen X; Gustafsson S; Whitington T; Borné Y; Lorentzen E; Sun J; Almgren P; Su J; Karlsson R; Song J; Lu Y; Zhan Y; Hägg S; Svensson P; Smedby KE; Slager SL; Ingelsson E; Lindgren CM; Morris AP; Melander O; Karlsson T; de Faire U; Caidahl K; Engström G; Lind L; Karlsson MCI; Pedersen NL; Frostegård J; Magnusson PKE
• Article: SCIENTIFIC REPORTS. 2018;8(1):7526

  Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants.

  Zhou A; Taylor AE; Karhunen V; Zhan Y; Rovio SP; Lahti J; Sjögren P; Byberg L; Lyall DM; Auvinen J; Lehtimäki T; Kähönen M; Hutri-Kähönen N; Perälä MM; Michaëlsson K; Mahajan A; Lind L; Power C; Eriksson JG; Raitakari OT; Hägg S; Pedersen NL; Veijola J; Järvelin M-R; Munafò MR; Ingelsson E; Llewellyn DJ; Hyppönen E
• Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2018;7(9):e007806

  Genetic and Environmental Contributions to the Covariation Between Cardiometabolic Traits.

  Chen X; Kuja-Halkola R; Chang Z; Karlsson R; Hägg S; Svensson P; Pedersen NL; Magnusson PKE
• Preprint: BIORXIV. 2018

  Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimer’s disease risk

  Jansen I; Savage J; Watanabe K; Bryois J; Williams D; Steinberg S; Sealock J; Karlsson I; Hägg S; Athanasiu L; Voyle N; Proitsi P; Witoelar A; Stringer S; Aarsland D; Almdahl I; Andersen F; Bergh S; Bettella F; Bjornsson S; Brækhus A; Bråthen G; de Leeuw C; Desikan R; Djurovic S; Dumitrescu L; Fladby T; Homan T; Jonsson P; Kiddle S; Rongve A; Saltvedt I; Sando S; Selbæk G; Skenne N; Snaedal J; Stordal E; Ulstein I; Wang Y; White L; Hjerling-Leffler J; Sullivan P; van der Flier W; Dobson R; Davis L; Stefansson H; Stefansson K; Pedersen N; Ripke S; Andreassen O; Posthuma D
• Editorial comment: CIRCULATION RESEARCH. 2018;122(4):546-547

  Telomere Length Dynamics and Atherosclerotic Disease.

  Hägg S
• Article: GENES. 2018;9(2):E78-78

  DNA Methylation and All-Cause Mortality in Middle-Aged and Elderly Danish Twins.

  Svane AM; Soerensen M; Lund J; Tan Q; Jylhävä J; Wang Y; Pedersen NL; Hägg S; Debrabant B; Deary IJ; Christensen K; Christiansen L; Hjelmborg JB
• Article: NEUROLOGY. 2018;90(4):e291-e297

  Circulating insulin-like growth factors and Alzheimer disease: A mendelian randomization study.

  Williams DM; Karlsson IK; Pedersen NL; Hägg S
• Article: METHODS IN MOLECULAR BIOLOGY. 2018;1750:293-306

  Telomere Length Shortening in Alzheimer's Disease: Procedures for a Causal Investigation Using Single Nucleotide Polymorphisms in a Mendelian Randomization Study.

  Zhan Y; Hägg S
• Conference publication: EUROPEAN JOURNAL OF HUMAN GENETICS. 2018;26:749-750

  Development of a robust method to study epigenetic changes in highly degraded FFPE DNA

  Hertoghs K; Wang Y; Behrouz F; Graff C; van Wezel T; van Iterson M; Pedersen N; Hagg S; Janssen B
• Preprint: F1000RES. 2018

  Positive bias for European men in peer reviewed applications for faculty position at Karolinska Institutet

  Holst S; Hägg S
• Conference publication: HUMAN GENOMICS. 2018;12

  GWAS meta-analysis (N=279,930) identifies new genes and functional links to general cognitive ability

  Savage JE; Jansen PR; Stringer S; Watanabe K; Bryois J; de Leeuw CA; Nagel M; Awasthi S; Barr PB; Coleman JRI; Grasby KL; Hammerschlag AR; Kaminski J; Karlsson R; Krapohl E; Lam M; Nygaard M; Reynolds CA; Trampush JW; Young H; Zabaneh D; Hagg S; Hansell NK; Karlsson IK; Linnarsson S; Montgomery GW; Munoz-Manchado AB; Quinlan EB; Schumann G; Skene N; Webb BT; White T; Arking DE; Attix DK; Avramopoulos D; Bilder RM; Bitsios P; Burdick KE; Cannon TD; Chiba-Falek O; Christoforou A; Cirulli ET; Congdon E; Corvin A; Davies G; Deary IJ; DeRosse P; Dickinson D; Djurovic S; Donohoe G; Conley ED; Eriksson JG; Espeseth T; Freimer NA; Giakoumaki S; Giegling I; Gill M; Glahn DC; Hariri AR; Hatzimanolis A; Keller MC; Knowles E; Konte B; Lahti J; Le Hellard S; Lencz T; Liewald DC; London E; Lundervold AJ; Malhotra AK; Melle I; Morris D; Need AC; Ollier W; Palotie A; Payton A; Pendleton N; Poldrack RA; Raikkonen K; Reinvang I; Roussos P; Rujescu D; Sabb FW; Scult MA; Smeland OB; Smyrnis N; Starr JM; Steen VM; Stefanis NC; Straub RE; Sundet K; Voineskos AN; Weinberger DR; Widen E; Yu J; Abecasis G; Andreassen OA; Breen G; Christiansen L; Debrabant B; Dick DM; Heinz A; Hjerling-Leffler J; Ikram MA; Kendler KS; Martin NG; Medland SE; Pedersen NL; Plomin R; Polderman TJC; Ripke S; van der Sluis S; Sullivan PF; Tiemeier H; Vrieze SI; Wright MJ; Posthuma D
• Article: AGING-US. 2017;9(12):2629-2646

  Frailty index as a predictor of all-cause and cause-specific mortality in a Swedish population-based cohort.

  Jiang M; Foebel AD; Kuja-Halkola R; Karlsson I; Pedersen NL; Hägg S; Jylhävä J
• Journal article: F1000RESEARCH. 2017;6:2145

  Positive bias for European men in peer reviewed applications for faculty position at Karolinska Institutet

  Holst S; Hägg S
• Preprint: BIORXIV. 2017

  A frailty index for UK Biobank participants

  Williams D; Jylhävä J; Pedersen N; Hägg S
• Article: MOLECULAR PSYCHIATRY. 2017;22(12):1680-1690

  An epigenome-wide association study meta-analysis of educational attainment.

  Karlsson Linnér R; Marioni RE; Rietveld CA; Simpkin AJ; Davies NM; Watanabe K; Armstrong NJ; Auro K; Baumbach C; Bonder MJ; Buchwald J; Fiorito G; Ismail K; Iurato S; Joensuu A; Karell P; Kasela S; Lahti J; McRae AF; Mandaviya PR; Seppälä I; Wang Y; Baglietto L; Binder EB; Harris SE; Hodge AM; Horvath S; Hurme M; Johannesson M; Latvala A; Mather KA; Medland SE; Metspalu A; Milani L; Milne RL; Pattie A; Pedersen NL; Peters A; Polidoro S; Räikkönen K; Severi G; Starr JM; Stolk L; Waldenberger M; Eriksson JG; Esko T; Franke L; Gieger C; Giles GG; Hägg S; Jousilahti P; Kaprio J; Kähönen M; Lehtimäki T; Martin NG; van Meurs JBC; Ollikainen M; Perola M; Posthuma D; Raitakari OT; Sachdev PS; Taskesen E; Uitterlinden AG; Vineis P; Wijmenga C; Wright MJ; Relton C; Davey Smith G; Deary IJ; Koellinger PD; Benjamin DJ
• Preprint: BIORXIV. 2017

  Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

  Wang Y; Karlsson R; Lampa E; Zhang Q; Hedman Å; Almgren M; Almqvist C; McRae A; Marioni R; Ingelsson E; Visscher P; Deary I; Lind L; Morris T; Beck S; Pedersen N; Hägg S
• Preprint: BIORXIV. 2017

  The frailty index is associated with the need for care in an aging Swedish population

  Jylhävä J; Jiang M; Foebel AD; Pedersen NL; Hägg S
• Preprint: BIORXIV. 2017

  Frailty index as a predictor of all-cause and cause-specific mortality in a Swedish population-based cohort

  Jiang M; Foebel AD; Kuja-Halkola R; Karlsson I; Pedersen NL; Hägg S; Jylhävä J
• Article: SCIENTIFIC REPORTS. 2017;7(1):13230

  Vitamin D and cognitive function: A Mendelian randomisation study.

  Maddock J; Zhou A; Cavadino A; Kuźma E; Bao Y; Smart MC; Saum K-U; Schöttker B; Engmann J; Kjærgaard M; Karhunen V; Zhan Y; Lehtimäki T; Rovio SP; Byberg L; Lahti J; Marques-Vidal P; Sen A; Perna L; Schirmer H; Singh-Manoux A; Auvinen J; Hutri-Kähönen N; Kähönen M; Kilander L; Räikkönen K; Melhus H; Ingelsson E; Guessous I; Petrovic KE; Schmidt H; Schmidt R; Vollenweider P; Lind L; Eriksson JG; Michaëlsson K; Raitakari OT; Hägg S; Pedersen NL; Herzig K-H; Järvelin M-R; Veijola J; Kivimaki M; Jorde R; Brenner H; Kumari M; Power C; Llewellyn DJ; Hyppönen E
• Preprint: BIORXIV. 2017

  GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

  Savage J; Jansen P; Stringer S; Watanabe K; Bryois J; de Leeuw C; Nagel M; Awasthi S; Barr P; Coleman J; Grasby K; Hammerschlag A; Kaminski J; Karlsson R; Krapohl E; Lam M; Nygaard M; Reynolds C; Trampush J; Young H; Zabaneh D; Hägg S; Hansell N; Karlsson I; Linnarsson S; Montgomery G; Muñoz-Manchado A; Quinlan E; Schumann G; Skene N; Webb B; White T; Arking D; Attix D; Avramopoulos D; Bilder R; Bitsios P; Burdick K; Cannon T; Chiba-Falek O; Christoforou A; Cirulli E; Congdon E; Corvin A; Davies G; Deary I; DeRosse P; Dickinson D; Djurovic S; Donohoe G; Conley ED; Eriksson J; Espeseth T; Freimer N; Giakoumaki S; Giegling I; Gill M; Glahn D; Hariri A; Hatzimanolis A; Keller M; Knowles E; Konte B; Lahti J; Hellard SL; Lencz T; Liewald D; London E; Lundervold A; Malhotra A; Melle I; Morris D; Need A; Ollier W; Palotie A; Payton A; Pendleton N; Poldrack R; Räikkönen K; Reinvang I; Roussos P; Rujescu D; Sabb F; Scult M; Smeland O; Smyrnis N; Starr J; Steen V; Stefanis N; Straub R; Sundet K; Voineskos A; Weinberger D; Widen E; Yu J; Abecasis G; Andreassen O; Breen G; Christiansen L; Debrabant B; Dick D; Heinz A; Hjerling-Leffler J; Ikram A; Kendler K; Martin N; Medland S; Pedersen N; Plomin R; Polderman TJC; Ripke S; Sluis SVD; Sullivan P; Tiemeier H; Vrieze S; Wright M; Posthuma D
• Preprint: BIORXIV. 2017

  Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

  Davies G; Lam M; Harris S; Trampush J; Luciano M; Hill D; Hagenaars S; Ritchie S; Marioni R; Fawns-Ritchie C; Liewald DCM; Okely J; Ahola-Olli A; Barnes CLK; Bertram L; Bis J; Burdick K; Christoforou A; DeRosse P; Djurovic S; Espeseth T; Giakoumaki S; Giddaluru S; Gustavson D; Hayward C; Hofer E; Ikram A; Karlsson R; Knowles E; Lahti J; Leber M; Li S; Mather K; Melle I; Morris D; Oldmeadow C; Palviainen T; Payton A; Pazoki R; Petrovic K; Reynolds C; Sargurupremraj M; Scholz M; Smith J; Smith A; Terzikhan N; Thalamuthu A; Trompet S; Lee SVD; Ware E; Windham G; Wright M; Yang J; Yu J; Ames D; Amin N; Amouyel P; Andreassen O; Armstrong N; Assareh A; Attia J; Attix D; Avramopoulos D; Bennett D; Böhmer A; Boyle P; Brodaty H; Campbell H; Cannon T; Cirulli E; Congdon E; Conley ED; Corley J; Cox S; Dale A; Dehghan A; Dick D; Dickinson D; Eriksson J; Evangelou E; Faul J; Ford I; Freimer N; Gao H; Giegling I; Gillespie N; Gordon S; Gottesman R; Griswold M; Gudnason V; Harris T; Hartmann A; Hatzimanolis A; Heiss G; Holliday E; Joshi P; Kähönen M; Kardia SLR; Karlsson I; Kleineidam L; Knopman D; Kochan N; Konte B; Kwok J; Hellard SL; Lee T; Lehtimäki T; Li S-C; Liu T; Koini M; London E; Longstreth W; Lopez O; Loukola A; Luck T; Lundervold A; Lundquist A; Lyytikäinen L-P; Martin N; Montgomery G; Murray A; Need A; Noordam R; Nyberg L; Ollier W; Papenberg G; Pattie A; Polasek O; Poldrack R; Psaty B; Reppermund S; Riedel-Heller S; Rose R; Rotter J; Roussos P; Rovio S; Saba Y; Sabb F; Sachdev P; Satizabal C; Schmid M; Scott R; Scult M; Simino J; Slagboom E; Smyrnis N; Soumaré A; Stefanis N; Stott D; Straub R; Sundet K; Taylor A; Taylor K; Tzoulaki I; Tzourio C; Uitterlinden A; Vitart V; Voineskos A; Kaprio J; Wagner M; Wagner H; Weinhold L; Wen H; Widen E; Yang Q; Zhao W; Adams HHH; Arking D; Bilder R; Bitsios P; Boerwinkle E; Chiba-Falek O; Corvin A; Jager PD; Debette S; Donohoe G; Elliott P; Fitzpatrick A; Gill M; Glahn D; Hägg S; Hansell N; Hariri A; Ikram K; Jukema W; Vuoksimaa E; Keller M; Kremen W; Launer L; Lindenberger U; Palotie A; Pedersen N; Pendleton N; Porteous D; Räikkönen K; Raitakari O; Ramirez A; Reinvang I; Rudan I; Rujescu D; Schmidt R; Schmidt H; Schofield P; Schofield P; Starr J; Steen V; Trollor J; Turner S; Duijn CV; Villringer A; Weinberger D; Weir D; Wilson J; Malhotra A; McIntosh A; Gale C; Seshadri S; Mosley T; Bressler J; Lencz T; Deary I
• Article: CIRCULATION RESEARCH. 2017;121(3):214-219

  Exploring the Causal Pathway From Telomere Length to Coronary Heart Disease: A Network Mendelian Randomization Study.

  Zhan Y; Karlsson IK; Karlsson R; Tillander A; Reynolds CA; Pedersen NL; Hägg S
• Journal article: INNOVATION IN AGING. 2017;1(suppl_1):1333-1334

  IS ALZHEIMER’S DISEASE INFLUENCED BY INSULIN-LIKE GROWTH FACTORS? A MENDELIAN RANDOMIZATION STUDY

  Williams D; Hägg S; Karlsson I; Pedersen NL
• Review: EBIOMEDICINE. 2017;21:29-36

  Biological Age Predictors.

  Jylhävä J; Pedersen NL; Hägg S
• Article: TRANSLATIONAL PSYCHIATRY. 2017;7(5):e1142

  Genetic susceptibility to cardiovascular disease and risk of dementia.

  Karlsson IK; Ploner A; Song C; Gatz M; Pedersen NL; Hägg S
• Article: TRANSLATIONAL PSYCHIATRY. 2017;7(4):e1100

  Short telomere length is associated with impaired cognitive performance in European ancestry cohorts.

  Hägg S; Zhan Y; Karlsson R; Gerritsen L; Ploner A; van der Lee SJ; Broer L; Deelen J; Marioni RE; Wong A; Lundquist A; Zhu G; Hansell NK; Sillanpää E; Fedko IO; Amin NA; Beekman M; de Craen AJM; Degerman S; Harris SE; Kan K-J; Martin-Ruiz CM; Montgomery GW; NeuroCHARGE Cognitive Working Group; Adolfsson AN; Reynolds CA; Samani NJ; Suchiman HED; Viljanen A; von Zglinicki T; Wright MJ; Hottenga J-J; Boomsma DI; Rantanen T; Kaprio JA; Nyholt DR; Martin NG; Nyberg L; Adolfsson R; Kuh D; Starr JM; Deary IJ; Slagboom PE; van Duijn CM; Codd V; Pedersen NL
• Preprint: BIORXIV. 2017

  An epigenome-wide association study of educational attainment (n = 10,767)

  Karlsson Linnér R; Marioni R; Rietveld C; Simpkin A; Davies N; Watanabe K; Armstrong N; Auro K; Baumbach C; Bonder MJ; Buchwald J; Fiorito G; Ismail K; Iurato S; Joensuu A; Karell P; Kasela S; Lahti J; McRae A; Mandaviya P; Seppälä I; Wang Y; Baglietto L; Binder E; Harris S; Hodge A; Horvath S; Hurme M; Johannesson M; Latvala A; Mather K; Medland S; Metspalu A; Milani L; Milne R; Pattie A; Pedersen N; Peters A; Polidoro S; Räikkönen K; Severi G; Starr J; Stolk L; Waldenberger M; Eriksson J; Esko T; Franke L; Gieger C; Giles G; Hägg S; Jousilahti P; Kaprio J; Kähönen M; Lehtimäki T; Martin N; van Meurs J; Ollikainen M; Perola M; Posthuma D; Raitakari O; Sachdev P; Taskesen E; Uitterlinden A; Vineis P; Wijmenga C; Wright M; Relton C; Davey Smith G; Deary I; Koellinger P; Benjamin D; BIOS Consortium
• Article: F1000RESEARCH. 2017;6:2145

  Positive bias for European men in peer reviewed applications for faculty position at Karolinska Institutet.

  Holst S; Hägg S
• Conference publication: BEHAVIOR GENETICS. 2017;47(6):709

  DNA methylation in Alzheimer's disease associated genes

  Karlsson I; Ploner A; Wang Y; Pedersen NL; Hagg S
• Conference publication: BEHAVIOR GENETICS. 2017;47(6):706

  Longitudinal variance components of the Horvath clock and its contributing CpGs

  Jylhava J; Reynolds C; Hjelmborg J; Munoz E; Tan Q; Christiansen L; Hagg S; Pedersen NL
• Article: AGING-US. 2016;8(7):1398-1415

  Longitudinal decline of leukocyte telomere length in old age and the association with sex and genetic risk.

  Berglund K; Reynolds CA; Ploner A; Gerritsen L; Hovatta I; Pedersen NL; Hägg S
• Article: METABOLOMICS. 2016;12(1):4

  Large-scale non-targeted metabolomic profiling in three human population-based studies

  Ganna A; Fall T; Salihovic S; Lee W; Broeckling CD; Kumar J; Hagg S; Stenemo M; Magnusson PKE; Prenni JE; Lind L; Pawitan Y; Ingelsson E
• Article: HUMAN MOLECULAR GENETICS. 2015;24(23):6849-6860

  Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity.

  Hägg S; Ganna A; Van Der Laan SW; Esko T; Pers TH; Locke AE; Berndt SI; Justice AE; Kahali B; Siemelink MA; Pasterkamp G; GIANT Consortium; Strachan DP; Speliotes EK; North KE; Loos RJF; Hirschhorn JN; Pawitan Y; Ingelsson E
• Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2015;97(5):708-714

  Dominant Genetic Variation and Missing Heritability for Human Complex Traits: Insights from Twin versus Genome-wide Common SNP Models.

  Chen X; Kuja-Halkola R; Rahman I; Arpegård J; Viktorin A; Karlsson R; Hägg S; Svensson P; Pedersen NL; Magnusson PKE
• Letter: JAMA NEUROLOGY. 2015;72(10):1202-1203

  Telomere Length Shortening and Alzheimer Disease--A Mendelian Randomization Study.

  Zhan Y; Song C; Karlsson R; Tillander A; Reynolds CA; Pedersen NL; Hägg S
• Article: PLOS GENETICS. 2015;11(7):e1005230

  Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.

  Horikoshi M; Mӓgi R; van de Bunt M; Surakka I; Sarin A-P; Mahajan A; Marullo L; Thorleifsson G; Hӓgg S; Hottenga J-J; Ladenvall C; Ried JS; Winkler TW; Willems SM; Pervjakova N; Esko T; Beekman M; Nelson CP; Willenborg C; Wiltshire S; Ferreira T; Fernandez J; Gaulton KJ; Steinthorsdottir V; Hamsten A; Magnusson PKE; Willemsen G; Milaneschi Y; Robertson NR; Groves CJ; Bennett AJ; Lehtimӓki T; Viikari JS; Rung J; Lyssenko V; Perola M; Heid IM; Herder C; Grallert H; Müller-Nurasyid M; Roden M; Hypponen E; Isaacs A; van Leeuwen EM; Karssen LC; Mihailov E; Houwing-Duistermaat JJ; de Craen AJM; Deelen J; Havulinna AS; Blades M; Hengstenberg C; Erdmann J; Schunkert H; Kaprio J; Tobin MD; Samani NJ; Lind L; Salomaa V; Lindgren CM; Slagboom PE; Metspalu A; van Duijn CM; Eriksson JG; Peters A; Gieger C; Jula A; Groop L; Raitakari OT; Power C; Penninx BWJH; de Geus E; Smit JH; Boomsma DI; Pedersen NL; Ingelsson E; Thorsteinsdottir U; Stefansson K; Ripatti S; Prokopenko I; McCarthy MI; Morris AP; ENGAGE Consortium
• Article: MOLECULAR PSYCHIATRY. 2015;20(6):735-743

  The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.

  Peyrot WJ; Lee SH; Milaneschi Y; Abdellaoui A; Byrne EM; Esko T; de Geus EJC; Hemani G; Hottenga JJ; Kloiber S; Levinson DF; Lucae S; Major Depressive Disorder Working Group of the Psy; Martin NG; Medland SE; Metspalu A; Milani L; Noethen MM; Potash JB; Rietschel M; Rietveld CA; Ripke S; Shi J; Social Science Genetic Association Consortium Corp; Willemsen G; Zhu Z; Boomsma DI; Wray NR; Penninx BWJH; Major Depressive Disorder Working Group of the Psy; Social Science Genetic Association Consortium Corp
• Article: NATURE GENETICS. 2015;47(6):589-597

  The impact of low-frequency and rare variants on lipid levels.

  Surakka I; Horikoshi M; Mägi R; Sarin A-P; Mahajan A; Lagou V; Marullo L; Ferreira T; Miraglio B; Timonen S; Kettunen J; Pirinen M; Karjalainen J; Thorleifsson G; Hägg S; Hottenga J-J; Isaacs A; Ladenvall C; Beekman M; Esko T; Ried JS; Nelson CP; Willenborg C; Gustafsson S; Westra H-J; Blades M; de Craen AJM; de Geus EJ; Deelen J; Grallert H; Hamsten A; Havulinna AS; Hengstenberg C; Houwing-Duistermaat JJ; Hyppönen E; Karssen LC; Lehtimäki T; Lyssenko V; Magnusson PKE; Mihailov E; Müller-Nurasyid M; Mpindi J-P; Pedersen NL; Penninx BWJH; Perola M; Pers TH; Peters A; Rung J; Smit JH; Steinthorsdottir V; Tobin MD; Tsernikova N; van Leeuwen EM; Viikari JS; Willems SM; Willemsen G; Schunkert H; Erdmann J; Samani NJ; Kaprio J; Lind L; Gieger C; Metspalu A; Slagboom PE; Groop L; van Duijn CM; Eriksson JG; Jula A; Salomaa V; Boomsma DI; Power C; Raitakari OT; Ingelsson E; Järvelin M-R; Thorsteinsdottir U; Franke L; Ikonen E; Kallioniemi O; Pietiäinen V; Lindgren CM; Stefansson K; Palotie A; McCarthy MI; Morris AP; Prokopenko I; Ripatti S; ENGAGE Consortium
• Article: DIABETES. 2015;64(5):1841-1852

  Age- and sex-specific causal effects of adiposity on cardiovascular risk factors.

  Fall T; Hägg S; Ploner A; Mägi R; Fischer K; Draisma HHM; Sarin A-P; Benyamin B; Ladenvall C; Åkerlund M; Kals M; Esko T; Nelson CP; Kaakinen M; Huikari V; Mangino M; Meirhaeghe A; Kristiansson K; Nuotio M-L; Kobl M; Grallert H; Dehghan A; Kuningas M; de Vries PS; de Bruijn RFAG; Willems SM; Heikkilä K; Silventoinen K; Pietiläinen KH; Legry V; Giedraitis V; Goumidi L; Syvänen A-C; Strauch K; Koenig W; Lichtner P; Herder C; Palotie A; Menni C; Uitterlinden AG; Kuulasmaa K; Havulinna AS; Moreno LA; Gonzalez-Gross M; Evans A; Tregouet D-A; Yarnell JWG; Virtamo J; Ferrières J; Veronesi G; Perola M; Arveiler D; Brambilla P; Lind L; Kaprio J; Hofman A; Stricker BH; van Duijn CM; Ikram MA; Franco OH; Cottel D; Dallongeville J; Hall AS; Jula A; Tobin MD; Penninx BW; Peters A; Gieger C; Samani NJ; Montgomery GW; Whitfield JB; Martin NG; Groop L; Spector TD; Magnusson PK; Amouyel P; Boomsma DI; Nilsson PM; Järvelin M-R; Lyssenko V; Metspalu A; Strachan DP; Salomaa V; Ripatti S; Pedersen NL; Prokopenko I; McCarthy MI; Ingelsson E; ENGAGE Consortium
• Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2015;44(2):578-586

  Adiposity as a cause of cardiovascular disease: a Mendelian randomization study.

  Hägg S; Fall T; Ploner A; Mägi R; Fischer K; Draisma HHM; Kals M; de Vries PS; Dehghan A; Willems SM; Sarin A-P; Kristiansson K; Nuotio M-L; Havulinna AS; de Bruijn RFAG; Ikram MA; Kuningas M; Stricker BH; Franco OH; Benyamin B; Gieger C; Hall AS; Huikari V; Jula A; Järvelin M-R; Kaakinen M; Kaprio J; Kobl M; Mangino M; Nelson CP; Palotie A; Samani NJ; Spector TD; Strachan DP; Tobin MD; Whitfield JB; Uitterlinden AG; Salomaa V; Syvänen A-C; Kuulasmaa K; Magnusson PK; Esko T; Hofman A; de Geus EJC; Lind L; Giedraitis V; Perola M; Evans A; Ferrières J; Virtamo J; Kee F; Tregouet D-A; Arveiler D; Amouyel P; Gianfagna F; Brambilla P; Ripatti S; van Duijn CM; Metspalu A; Prokopenko I; McCarthy MI; Pedersen NL; Ingelsson E; European Network for Genetic and Genomic Epidemiol
• Conference publication: BEHAVIOR GENETICS. 2015;45(6):664

  Genetic susceptibility to cardiovascular disease and risk of dementia

  Karlsson I; Haegg S; Ploner A; Song C; Gatz M; Pedersen N
• Conference publication: GERONTOLOGIST. 2015;55

  Apolipoprotein E DNA Methylation in Dementia and Cardiovascular Disease

  Karlsson IK; Hagg S; Pedersen NL
• Journal article: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2014;165B(6):510-520

  Polygenic scores associated with educational attainment in adults predict educational achievement and ADHD symptoms in children.

  de Zeeuw EL; van Beijsterveldt CEM; Glasner TJ; Bartels M; Ehli EA; Davies GE; Hudziak JJ; Social Science Genetic Association Consortium; Rietveld CA; Groen-Blokhuis MM; Hottenga JJ; de Geus EJC; Boomsma DI
• Conference publication: ATHEROSCLEROSIS. 2014;235(2):E29

  PLASMA CHOLESTEROL-INDUCED REGRESSION OF EARLY, MATURE, AND ADVANCED ATHEROSCLEROSIS

  Bjorkegren JLM; Hagg S; Talukdar HA; Asl HF; Jain RK; Cedergren C; Shang MM; Rossignoli A; Takolander R; Melander O; Hamsten A; Michoel T; Skogsberg J
• Article: DIABETIC MEDICINE. 2014;31(7):787-793

  Serum selenium in relation to measures of glucose metabolism and incidence of Type 2 diabetes in an older Swedish population.

  Gao H; Hägg S; Sjögren P; Lambert PC; Ingelsson E; van Dam RM
• Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2014;43(3):878-886

  Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers.

  Deelen J; Beekman M; Codd V; Trompet S; Broer L; Hägg S; Fischer K; Thijssen PE; Suchiman HED; Postmus I; Uitterlinden AG; Hofman A; de Craen AJM; Metspalu A; Pedersen NL; van Duijn CM; Jukema JW; Houwing-Duistermaat JJ; Samani NJ; Slagboom PE
• Article: HUMAN MOLECULAR GENETICS. 2014;23(9):2490-2497

  DNA mismatch repair gene MSH6 implicated in determining age at natural menopause.

  Perry JRB; Hsu Y-H; Chasman DI; Johnson AD; Elks C; Albrecht E; Andrulis IL; Beesley J; Berenson GS; Bergmann S; Bojesen SE; Bolla MK; Brown J; Buring JE; Campbell H; Chang-Claude J; Chenevix-Trench G; Corre T; Couch FJ; Cox A; Czene K; D'adamo AP; Davies G; Deary IJ; Dennis J; Easton DF; Engelhardt EG; Eriksson JG; Esko T; Fasching PA; Figueroa JD; Flyger H; Fraser A; Garcia-Closas M; Gasparini P; Gieger C; Giles G; Guenel P; Hägg S; Hall P; Hayward C; Hopper J; Ingelsson E; kConFab investigators; Kardia SLR; Kasiman K; Knight JA; Lahti J; Lawlor DA; Magnusson PKE; Margolin S; Marsh JA; Metspalu A; Olson JE; Pennell CE; Polasek O; Rahman I; Ridker PM; Robino A; Rudan I; Rudolph A; Salumets A; Schmidt MK; Schoemaker MJ; Smith EN; Smith JA; Southey M; Stöckl D; Swerdlow AJ; Thompson DJ; Truong T; Ulivi S; Waldenberger M; Wang Q; Wild S; Wilson JF; Wright AF; Zgaga L; ReproGen Consortium; Ong KK; Murabito JM; Karasik D; Murray A
• Article: EUROPEAN RESPIRATORY JOURNAL. 2014;43(4):983-992

  Telomere length in circulating leukocytes is associated with lung function and disease.

  Albrecht E; Sillanpää E; Karrasch S; Alves AC; Codd V; Hovatta I; Buxton JL; Nelson CP; Broer L; Hägg S; Mangino M; Willemsen G; Surakka I; Ferreira MAR; Amin N; Oostra BA; Bäckmand HM; Peltonen M; Sarna S; Rantanen T; Sipilä S; Korhonen T; Madden PAF; Gieger C; Jörres RA; Heinrich J; Behr J; Huber RM; Peters A; Strauch K; Wichmann HE; Waldenberger M; Blakemore AIF; de Geus EJC; Nyholt DR; Henders AK; Piirilä PL; Rissanen A; Magnusson PKE; Viñuela A; Pietiläinen KH; Martin NG; Pedersen NL; Boomsma DI; Spector TD; van Duijn CM; Kaprio J; Samani NJ; Jarvelin M-R; Schulz H
• Preprint: BIORXIV. 2014

  A workflow for UPLC-MS non-targeted metabolomic profiling in large human population-based studies

  Ganna A; Fall T; Lee W; Broeckling CD; Kumar J; Hägg S; Magnusson PKE; Prenni J; Lind L; Pawitan Y; Ingelsson E
• Article: PLOS GENETICS. 2014;10(2):e1004201

  Plasma cholesterol-induced lesion networks activated before regression of early, mature, and advanced atherosclerosis.

  Björkegren JLM; Hägg S; Talukdar HA; Foroughi Asl H; Jain RK; Cedergren C; Shang M-M; Rossignoli A; Takolander R; Melander O; Hamsten A; Michoel T; Skogsberg J
• Article: CELL CYCLE. 2014;13(23):3645-3658

  Inactivation of the budding yeast cohesin loader Scc2 alters gene expression both globally and in response to a single DNA double strand break.

  Lindgren E; Hägg S; Giordano F; Björkegren J; Ström L
• Journal article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2013;23(suppl_1)

  Temporal trends in case-fatality of myocardial infarction and stroke by socioeconomic position in Sweden 1987-2010Ninoa Malki

  Malki N; Plone A; Koupil I; Hägg S; Tiikkaja S; Lambert P; Sparen P
• Article: SCIENCE. 2013;340(6139):1467-1471

  GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.

  Rietveld CA; Medland SE; Derringer J; Yang J; Esko T; Martin NW; Westra H-J; Shakhbazov K; Abdellaoui A; Agrawal A; Albrecht E; Alizadeh BZ; Amin N; Barnard J; Baumeister SE; Benke KS; Bielak LF; Boatman JA; Boyle PA; Davies G; de Leeuw C; Eklund N; Evans DS; Ferhmann R; Fischer K; Gieger C; Gjessing HK; Hägg S; Harris JR; Hayward C; Holzapfel C; Ibrahim-Verbaas CA; Ingelsson E; Jacobsson B; Joshi PK; Jugessur A; Kaakinen M; Kanoni S; Karjalainen J; Kolcic I; Kristiansson K; Kutalik Z; Lahti J; Lee SH; Lin P; Lind PA; Liu Y; Lohman K; Loitfelder M; McMahon G; Vidal PM; Meirelles O; Milani L; Myhre R; Nuotio M-L; Oldmeadow CJ; Petrovic KE; Peyrot WJ; Polasek O; Quaye L; Reinmaa E; Rice JP; Rizzi TS; Schmidt H; Schmidt R; Smith AV; Smith JA; Tanaka T; Terracciano A; van der Loos MJHM; Vitart V; Völzke H; Wellmann J; Yu L; Zhao W; Allik J; Attia JR; Bandinelli S; Bastardot F; Beauchamp J; Bennett DA; Berger K; Bierut LJ; Boomsma DI; Bültmann U; Campbell H; Chabris CF; Cherkas L; Chung MK; Cucca F; de Andrade M; De Jager PL; De Neve J-E; Deary IJ; Dedoussis GV; Deloukas P; Dimitriou M; Eiríksdóttir G; Elderson MF; Eriksson JG; Evans DM; Faul JD; Ferrucci L; Garcia ME; Grönberg H; Guðnason V; Hall P; Harris JM; Harris TB; Hastie ND; Heath AC; Hernandez DG; Hoffmann W; Hofman A; Holle R; Holliday EG; Hottenga J-J; Iacono WG; Illig T; Järvelin M-R; Kähönen M; Kaprio J; Kirkpatrick RM; Kowgier M; Latvala A; Launer LJ; Lawlor DA; Lehtimäki T; Li J; Lichtenstein P; Lichtner P; Liewald DC; Madden PA; Magnusson PKE; Mäkinen TE; Masala M; McGue M; Metspalu A; Mielck A; Miller MB; Montgomery GW; Mukherjee S; Nyholt DR; Oostra BA; Palmer LJ; Palotie A; Penninx BWJH; Perola M; Peyser PA; Preisig M; Räikkönen K; Raitakari OT; Realo A; Ring SM; Ripatti S; Rivadeneira F; Rudan I; Rustichini A; Salomaa V; Sarin A-P; Schlessinger D; Scott RJ; Snieder H; St Pourcain B; Starr JM; Sul JH; Surakka I; Svento R; Teumer A; LifeLines Cohort Study; Tiemeier H; van Rooij FJA; Van Wagoner DR; Vartiainen E; Viikari J; Vollenweider P; Vonk JM; Waeber G; Weir DR; Wichmann H-E; Widen E; Willemsen G; Wilson JF; Wright AF; Conley D; Davey-Smith G; Franke L; Groenen PJF; Hofman A; Johannesson M; Kardia SLR; Krueger RF; Laibson D; Martin NG; Meyer MN; Posthuma D; Thurik AR; Timpson NJ; Uitterlinden AG; van Duijn CM; Visscher PM; Benjamin DJ; Cesarini D; Koellinger PD
• Article: ACTA PHYSIOLOGICA. 2013;208(1):88-94

  Variation in genes in the endothelin pathway and endothelium-dependent and endothelium-independent vasodilation in an elderly population.

  Lind L; Syvänen A-C; Axelsson T; Lundmark P; Hägg S; Larsson A
• Article: DIABETES. 2013;62(4):1338-1344

  Evidence of a causal relationship between adiponectin levels and insulin sensitivity: a Mendelian randomization study.

  Gao H; Fall T; van Dam RM; Flyvbjerg A; Zethelius B; Ingelsson E; Hägg S
• Article: NATURE GENETICS. 2013;45(4):422-427e2

  Identification of seven loci affecting mean telomere length and their association with disease.

  Codd V; Nelson CP; Albrecht E; Mangino M; Deelen J; Buxton JL; Hottenga JJ; Fischer K; Esko T; Surakka I; Broer L; Nyholt DR; Mateo Leach I; Salo P; Hägg S; Matthews MK; Palmen J; Norata GD; O'Reilly PF; Saleheen D; Amin N; Balmforth AJ; Beekman M; de Boer RA; Böhringer S; Braund PS; Burton PR; de Craen AJM; Denniff M; Dong Y; Douroudis K; Dubinina E; Eriksson JG; Garlaschelli K; Guo D; Hartikainen A-L; Henders AK; Houwing-Duistermaat JJ; Kananen L; Karssen LC; Kettunen J; Klopp N; Lagou V; van Leeuwen EM; Madden PA; Mägi R; Magnusson PKE; Männistö S; McCarthy MI; Medland SE; Mihailov E; Montgomery GW; Oostra BA; Palotie A; Peters A; Pollard H; Pouta A; Prokopenko I; Ripatti S; Salomaa V; Suchiman HED; Valdes AM; Verweij N; Viñuela A; Wang X; Wichmann H-E; Widen E; Willemsen G; Wright MJ; Xia K; Xiao X; van Veldhuisen DJ; Catapano AL; Tobin MD; Hall AS; Blakemore AIF; van Gilst WH; Zhu H; CARDIoGRAM consortium; Erdmann J; Reilly MP; Kathiresan S; Schunkert H; Talmud PJ; Pedersen NL; Perola M; Ouwehand W; Kaprio J; Martin NG; van Duijn CM; Hovatta I; Gieger C; Metspalu A; Boomsma DI; Jarvelin M-R; Slagboom PE; Thompson JR; Spector TD; van der Harst P; Samani NJ
• Article: PLOS MEDICINE. 2013;10(6):e1001474

  The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.

  Fall T; Hägg S; Mägi R; Ploner A; Fischer K; Horikoshi M; Sarin A-P; Thorleifsson G; Ladenvall C; Kals M; Kuningas M; Draisma HHM; Ried JS; van Zuydam NR; Huikari V; Mangino M; Sonestedt E; Benyamin B; Nelson CP; Rivera NV; Kristiansson K; Shen H-Y; Havulinna AS; Dehghan A; Donnelly LA; Kaakinen M; Nuotio M-L; Robertson N; de Bruijn RFAG; Ikram MA; Amin N; Balmforth AJ; Braund PS; Doney ASF; Döring A; Elliott P; Esko T; Franco OH; Gretarsdottir S; Hartikainen A-L; Heikkilä K; Herzig K-H; Holm H; Hottenga JJ; Hyppönen E; Illig T; Isaacs A; Isomaa B; Karssen LC; Kettunen J; Koenig W; Kuulasmaa K; Laatikainen T; Laitinen J; Lindgren C; Lyssenko V; Läärä E; Rayner NW; Männistö S; Pouta A; Rathmann W; Rivadeneira F; Ruokonen A; Savolainen MJ; Sijbrands EJG; Small KS; Smit JH; Steinthorsdottir V; Syvänen A-C; Taanila A; Tobin MD; Uitterlinden AG; Willems SM; Willemsen G; Witteman J; Perola M; Evans A; Ferrières J; Virtamo J; Kee F; Tregouet D-A; Arveiler D; Amouyel P; Ferrario MM; Brambilla P; Hall AS; Heath AC; Madden PAF; Martin NG; Montgomery GW; Whitfield JB; Jula A; Knekt P; Oostra B; van Duijn CM; Penninx BWJH; Smith GD; Kaprio J; Samani NJ; Gieger C; Peters A; Wichmann HE; Boomsma DI; de Geus EJC; Tuomi T; Power C; Hammond CJ; Spector TD; Lind L; Orho-Melander M; Palmer CNA; Morris AD; Groop L; Järvelin M-R; Salomaa V; Vartiainen E; Hofman A; Ripatti S; Metspalu A; Thorsteinsdottir U; Stefansson K; Pedersen NL; McCarthy MI; Ingelsson E; Prokopenko I; European Network for Genetic and Genomic Epidemiol
• Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2013;42

  Telomere length in circulating leukocytes is associated with lung function and disease

  Schulz H; Sillanpaa E; Karrasch S; Alves AC; Codd V; Hovatta I; Buxton JL; Nelson CP; Broer L; Hagg S; Mangino M; Willemsen G; Pietilainen KH; Ferreira MAR; Amin N; Oostra BA; Backmand HM; Peltonen M; Sarna S; Rantanen T; Sipila S; Korhonen T; Madden PAF; Gieger C; Joerres RA; Heinrich J; Behr J; Huber RM; Peters A; Strauch K; Wichmann H-E; Waldenberger M; Blakemore AIF; de Geus EJC; Nyholt N; Henders AK; Piirila PL; Surakka I; Rissanen A; Magnusson PKE; Vinuela A; Martin NG; Pedersen NL; Boomsma DI; Spector TD; van Duijn CM; Kaprio J; Samani NJ; Jarvelin M-R; Albrecht E
• Conference publication: DIABETOLOGIA. 2013;56:S60

  Pleiotropic effects on lipid levels and obesity identified in multi-trait meta-analysis of genome-wide association studies (GWAS) of type 2 diabetes related traits

  Lagou V; Maegi R; Surakka I; Sarin A-P; Horikoshi M; Thorleifsson G; Hagg S; Beekman M; Ladenvall C; Hottenga J-J; Ried JS; McCarthy MI; Morris A; Ripatti S; Prokopenko I
• Article: BMC PUBLIC HEALTH. 2012;12:664

  Relative deprivation and mortality--a longitudinal study in a Swedish population of 4.7 million, 1990-2006.

  Åberg Yngwe M; Kondo N; Hägg S; Kawachi I
• Conference publication: CIRCULATION. 2012;126(21)

  Evidence of a Causal Relationship between Adiponectin Levels and Insulin Sensitivity: A Mendelian Randomization Study

  Gao H; Fall T; van Dam RM; Flyvbjerg A; Zethelius B; Ingelsson E; Hagg S
• Conference publication: GENETIC EPIDEMIOLOGY. 2012;36(7):776-777

  Large-scale Genome-wide Association Meta-analysis Using Imputation from 2188-haplotype 1000 Genomes Reference Panel Identifies Novel Susceptibility Loci for Anthropometric and Glycemic Traits

  Magi R; Horikoshi M; Surakka I; Wiltshire S; Sarin A-P; Mahajan A; Marullo L; Ferreira T; Hagg S; Ried JS; Winkler T; Thorleifsson G; Tsernikova N; Esko T; Willenborg C; Nelson CP; Beekman M; Willems SM; McCarthy MI; Morris AP; Lindgren CM; Ripatti S; Prokopenko I
• Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2011;27(6):851-857

  Blood levels of dual-specificity phosphatase-1 independently predict risk for post-operative morbidities causing prolonged hospitalization after coronary artery bypass grafting.

  Hägg S; Alserius T; Noori P; Ruusalepp A; Ivert T; Tegnér J; Björkegren J; Skogsberg J
• Journal article: [TITLE FIELD MISSING]. 2011;12(1):64

  295 ATHEROSCLEROSIS REGRESSION IN A MOUSE MODEL WITH HUMAN-LIKE HYPERCHOLESTEROLEMIA

  Björkegren J; Hägg S; Maleki S; Shang M; Michoel T; Skogsberg J
• Article: PLOS ONE. 2011;6(4):e18248

  Carotid plaque age is a feature of plaque stability inversely related to levels of plasma insulin.

  Hägg S; Salehpour M; Noori P; Lundström J; Possnert G; Takolander R; Konrad P; Rosfors S; Ruusalepp A; Skogsberg J; Tegnér J; Björkegren J
• Conference publication: ATHEROSCLEROSIS SUPPLEMENTS. 2011;12(1):64

  ATHEROSCLEROSIS REGRESSION IN A MOUSE MODEL WITH HUMAN-LIKE HYPERCHOLESTEROLEMIA

  Bjoerkegren J; Haegg S; Maleki S; Shang M; Michoel T; Skogsberg J
• Article: PLOS GENETICS. 2009;5(12):e1000754

  Multi-organ expression profiling uncovers a gene module in coronary artery disease involving transendothelial migration of leukocytes and LIM domain binding 2: the Stockholm Atherosclerosis Gene Expression (STAGE) study.

  Hägg S; Skogsberg J; Lundström J; Noori P; Nilsson R; Zhong H; Maleki S; Shang M-M; Brinne B; Bradshaw M; Bajic VB; Samnegård A; Silveira A; Kaplan LM; Gigante B; Leander K; de Faire U; Rosfors S; Lockowandt U; Liska J; Konrad P; Takolander R; Franco-Cereceda A; Schadt EE; Ivert T; Hamsten A; Tegnér J; Björkegren J
• Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):357

  The Stockholm atherosclerosis gene expression (stage) study -: Multiorgan expression profiling in well-characterized coronary artery disease patients

  Hägg S; Lundström J; Skogsberg J; Nilsson R; Hallén K; Noori P; Ivert T; Hamsten A; Tegnér J; Björkegren J
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  Doktorand

  E-postadress katalin.vincze@ki.se
• Daniel Wikström Shemer

  Anknuten till Forskning

  E-postadress daniel.wikstrom.shemer@ki.se

Besöksadress

Karolinska Institute, Department of Medical Epidemiology and Biostatistics, Nobels väg 12A, Stockholm, 171 77, Sweden

Postadress

Karolinska Institutet, Department of Medical Epidemiology and Biostatistics, PO Box 281, Stockholm, 171 77, Sweden