Tanskriptionell grund för icke-genetisk cellulär heterogenitet – Vicent Pelechanos grupp

Publikationer

Utvalda publikationer

• Article: SCIENCE ADVANCES. 2023;9(36):eadi4997

  Digital assay for rapid electronic quantification of clinical pathogens using DNA nanoballs.

  Tayyab M; Barrett D; van Riel G; Liu S; Reinius B; Scharfe C; Griffin P; Steinmetz LM; Javanmard M; Pelechano V
• Article: NATURE MICROBIOLOGY. 2023;8(6):1123-1136

  Atlas of mRNA translation and decay for bacteria.

  Huch S; Nersisyan L; Ropat M; Barrett D; Wu M; Wang J; Valeriano VD; Vardazaryan N; Huerta-Cepas J; Wei W; Du J; Steinmetz LM; Engstrand L; Pelechano V
• Article: NATURE COMMUNICATIONS. 2023;14(1):910

  Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation.

  Li B; Zeis P; Zhang Y; Alekseenko A; Fürst E; Sanchez YP; Lin G; Tekkedil MM; Piazza I; Steinmetz LM; Pelechano V
• Article: NAR GENOMICS AND BIOINFORMATICS. 2022;4(2):lqac048

  OPUSeq simplifies detection of low-frequency DNA variants and uncovers fragmentase-associated artifacts.

  Alekseenko A; Wang J; Barrett D; Pelechano V
• Article: CELL REPORTS METHODS. 2021;1(1):100001

  High-throughput 5'P sequencing enables the study of degradation-associated ribosome stalls.

  Zhang Y; Pelechano V
• Article: SCIENTIFIC REPORTS. 2021;11(1):1820

  Direct detection of SARS-CoV-2 using non-commercial RT-LAMP reagents on heat-inactivated samples.

  Alekseenko A; Barrett D; Pareja-Sanchez Y; Howard RJ; Strandback E; Ampah-Korsah H; Rovšnik U; Zuniga-Veliz S; Klenov A; Malloo J; Ye S; Liu X; Reinius B; Elsässer SJ; Nyman T; Sandh G; Yin X; Pelechano V
• Article: NAR GENOMICS AND BIOINFORMATICS. 2020;2(4):lqaa099

  Improved computational analysis of ribosome dynamics from 5'P degradome data using fivepseq.

  Nersisyan L; Ropat M; Pelechano V
• Article: NUCLEIC ACIDS RESEARCH. 2020;48(18):e104

  TIF-Seq2 disentangles overlapping isoforms in complex human transcriptomes.

  Wang J; Li B; Marques S; Steinmetz LM; Wei W; Pelechano V
• Article: GENOME RESEARCH. 2019;29(12):1974-1984

  Chromatin-sensitive cryptic promoters putatively drive expression of alternative protein isoforms in yeast.

  Wei W; Hennig BP; Wang J; Zhang Y; Piazza I; Pareja Sanchez Y; Chabbert CD; Adjalley SH; Steinmetz LM; Pelechano V
• Article: CELL. 2015;161(6):1400-1412

  Widespread Co-translational RNA Decay Reveals Ribosome Dynamics.

  Pelechano V; Wei W; Steinmetz LM
• Article: NATURE. 2013;497(7447):127-131

  Extensive transcriptional heterogeneity revealed by isoform profiling.

  Pelechano V; Wei W; Steinmetz LM

Medarbetare och kontakt

Gruppledare

• 

  Vicente Pelechano Garcia

  Senior Forskare | Docent

  E-postadress vicente.pelechano.garcia@ki.se

Alla medlemmar i gruppen

• 

  Donal Barrett

  Doktorand | Laboratorietekniker

  E-postadress donal.barrett@ki.se
• Guido Baselli

  Postdoktor

  E-postadress guido.baselli@ki.se
• 

  Eva Brinkman

  Postdoktor

  E-postadress eva.brinkman@ki.se
• Adriana Carvajal Jimenez

  Doktorand

  E-postadress adriana.carvajal.jimenez@ki.se
• 

  Susanne Huch

  Forskningsspecialist

  E-postadress susanne.huch@ki.se
• Ryan Hull

  Postdoktor

  E-postadress ryan.hull@ki.se
• Honglian Liu

  Doktorand

  E-postadress honglian.liu@ki.se
• Mandy Meijer

  Anknuten till Forskning | Postdoktor

  E-postadress mandy.meijer@ki.se
• 

  Yerma Pareja Sanchez

  Forskningsingenjör

  E-postadress yerma.pareja.sanchez@ki.se
• 

  Vicente Pelechano Garcia

  Senior Forskare | Docent

  E-postadress vicente.pelechano.garcia@ki.se
• Ilaria Piazza

  Senior Forskare

  E-postadress ilaria.piazza@ki.se
• Carlos Santolaria Bello

  Postdoktorala Studier

  E-postadress carlos.santolaria.bello@ki.se
• 

  Irene Stevens

  Doktorand

  E-postadress irene.stevens@ki.se
• 

  Marcel Tarbier

  Postdoktor

  E-postadress marcel.tarbier@ki.se
• Anna Toldrá Filella

  Postdoktor

  E-postadress anna.toldra.filella@ki.se
• Yujie Zhang

  Postdoktor

  E-postadress yujie.zhang@ki.se
• Hui Zhou

  Postdoktor

  E-postadress hui.zhou@ki.se
• Nynke Boukje van Eijk

  Annan Grund

  E-postadress nynke.boukje.van.eijk@ki.se