Ortopedi – Anders Enocsons forskargrupp

Trauma

Ansvarig Anders Enocson

• Epidemiology and mortality of pelvic fractures
• Bleeding in pelvic fractures
• Arthroplasty for acetabular fractures
• Clinical and radiological outcome of pelvic fractures
• 3D computer tomography (CT) with motion analysis (CTMA) of pelvic fractures
• National epidemiology of trauma patients
• Artificial intelligence (AI)/machine learning analysis of trauma patients
• Computer tomography (CT) analysis of fracture healing
• Epidemiology and mortality of hip and femoral fractures
• Epidemiology and outcome of open tibial fractures
• Development of a clinical CT-based method for assessment of SI-joint instability
• Surgical treatment of chronic and acute acromioclavicular dislocations
• Validation of the Rockwood radiological classification for acromioclavicular dislocations
• A machine learning model for analysis of risk factors for mortality in hip fracture patients
• D-vitamin deficiency and its effect on fracture healing
• Muscle mass and tendon function after ankle fractures
• Clinical function, osteoporosis and sarcopenia 10 years after a femoral neck fracture in patients younger than 70 years

Artroplastik

• Mortality and patient reported outcome after acute deep infection after primary total hip replacement
• Effect of a national improvement program (PRISS) on the incidence of periprosthetic infection after total hip replacement
• Is an automated registry data analysis as good as medical records analysis in estimating deep infection after total hip replacement
• Development of a clinical CT-based method for assessment of total knee replacement loosening
• Clinical and qualitative long-term follow-up of ASR hip arthroplasty
• National long-term follow-up of BHR and ASR hip arthroplasty
• Evaluation of multiple hip- and knee-prosthesis surgery within the national prosthesis registers
• Socioeconomic factors related to multiple hip- and knee-prosthesis surgery
• Complications in patients after cancellation of elective orthopedic surgery compared with patients having their planned surgery
• Patients participation and evaluation of preoperative information on risk of complication after elective surgery

Pedagogik

Ansvarig Wilhelmina Ekström

• Person-centered ward round – students and patients’ perception on content
• Students perception on the value of anatomical workshop in the course of surgery

Integrativ ortopedi

Ansvarig Paul Ackermann

STOP Leg Clots - nationell multicenterstudie (webbplats). En nationell studie som undersöker om risken för att drabbas av djup ventrombos vid underbensimmobilisering kan minskas genom en mekanisk pump, s.k. intermittent pneumatisk muskelkompression.

• Decreased levels of SP after denervation are correlated with reduced mechanical properties in healing Achilles tendon
• Neuronal pathways in tendon healing
• Inflammatoriska geners/molekylers mönster vid traumatisk ledskada, med fokus på ledhinna
• Immobilization Up-regulates Early Expression of Sensory Neuropeptides
• Impaired Expression of the Growth Associated Protein-43 in Peripheral Tissues of A Diabetic Animal Model-the Leptin Receptor Knockout Mice
• Diabetes Mellitus Impairs Proliferative Tendon Repair
• Diabetes Mellitus Hampers Nerve Growth Factor Receptor in Tendon Repair
• IGF1-R Downregulated in Diabetic Tendon Repair
• HA Gels for Delivery of SP in Tendon Repair
• Chemokine Expression In Tendon Repair
• Compression Therapy Promotes Tissue Perfusion And Gene Expression
• Intermittent Foot Compression under Plaster Cast for prevention of Venous Thromboembolism remains questionable
• Metabolic Activity in Early Human Achilles Tendon Repair Can Be Enhanced by Intermittent Pneumatic Compression
• Improved Functional Outcome After Compression Treatment During Tendon Immobilization
• Decreased Thrombosis Incidence Correlates to Improved Healing and Function After Immobilization
• Interleukin 6 is up-regulated by Intermittent Pneumatic Compression during Achilles Tendon Repair
• Stem cells in Achilles tendon repair
• Glutamate Receptors In Tendinopathic Patients
• Injection Of NMDA-Receptor Antagonists Inhibit Tendinopathic Pain
• Resistance exercise using flywheel technology promotes higher quadriceps activation

Tumör

Ansvarig Henrik Bauer

• Indication for post-operative radiotherapy after surgical treatment of a pathological fracture.
• Functional outcome after surgery for a pathological fracture of the femur.
• Outcome of surgery of skeletal metastases in patients with colorectal cancer.
• Outcome of surgery for acral skeletal metastases.
• Use and validation of the PathFx for prognostication of patients with bone metastases.
• Characterization of the immune cell presence and interactions in soft-tissue sarcomas.
• Ewing sarcoma: when is adjuvant radiotherapy needed.
• The role of fine needle aspiration in diagnosis of soft tissue tumors.
• Scandinavian sarcoma group Registry.
• In vitro evaluation of the chemotherapy response of bone sarcomas.
• Cytogenetic analysis of bone and soft-tissue sarcomas.
• The use of CT-guided fine-needle aspiration in the diagnosis of bone tumours.
• Validation of secondary opinion by musculoskeletal radiologists.
• Pathological pulmonary nodules in sarcoma patients: characteristics associated with metastatic disease.
• How doctor’s and patient’s delay affect the clinical outcome in sarcomas.