Petter Brodins forskargrupp

Publikationer

Alla gruppmedlemmars publikationer

• Article: CELL. 2025;:S0092-8674(24)01427-2

  Systems-level immunomonitoring in children with solid tumors to enable precision medicine.

  Chen Q; Zhao B; Tan Z; Hedberg G; Wang J; Gonzalez L; Mugabo CH; Johnsson A; Negrini E; Páez LP; Rodriguez L; James A; Chen Y; Mikeš J; Bernhardsson AK; Reitzner SM; von Walden F; O'Neill O; Barcenilla H; Wang C; Davis MM; Carlson L-M; Pal N; Blomgren K; Repsilber D; Herold N; Lakshmikanth T; Kogner P; Ljungblad L; Brodin P
• Journal article: NATURE IMMUNOLOGY. 2025;26(1):7-8

  Platelet partnerships and lasting memories

  Brodin P
• Journal article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2025;121(1):60-73

  Human milk feeding practices and serum immune profiles of one-year-old infants in the CHILD birth cohort study

  Ames SR; Lotoski LC; Rodriguez L; Brodin P; Mandhane PJ; Moraes TJ; Simons E; Turvey SE; Subbarao P; Azad MB
• Article: PEDIATRIC INFECTIOUS DISEASE JOURNAL. 2025;44(1):54-57

  Cytokine Profile in Children Following SARS-CoV-2 Infection: Preliminary Findings

  Buonsenso D; Camporesi A; Di Sante G; Sali M; Boza MDCP; Morello R; Valentini P; Raffaelli F; Rodriguez L; Gonzalez L; Johnsson A; Mugabo CH; Lakshmikanth T; Brodin P
• Review: RHEUMATOLOGY. 2025;64(1):32-44

  Current treatment in macrophage activation syndrome worldwide: a systematic literature review to inform the METAPHOR project

  Baldo F; Erkens RGA; Mizuta M; Rogani G; Lucioni F; Bracaglia C; Foell D; Gattorno M; Jelusic M; Anton J; Brogan P; Canna S; Chandrakasan S; Cron RQ; De Benedetti F; Grom A; Heshin-Bekenstein M; Horne A; Khubchandani R; Ozen S; Quartier P; Ravelli A; Shimizu M; Schulert G; Scott C; Sinha R; Ruperto N; Swart JF; Vastert S; Minoia F
• Article: NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION. 2025;12(1):e200327

  Spectrum of Clinical and Imaging Features of Children With GFAP Astrocytopathy

  Sommer S; Panzer A; Bertolini A; Cleaveland R; Jain V; Kapanci T; Derichs U; Geis T; Neu A; Loehr-Nilles C; Aeschimann-Huhn R; Flotats-Bastardas M; Deiva K; Armangue T; Olive-Cirera G; Kannoth S; Koy A; Meirson H; Fattal-Valevski A; Ganelin-Cohen E; Losch H; Horne A; Wickstroem R; Dargvainiene J; Leypoldt F; Rostasy K
• Article: RHEUMATOLOGY. 2025;64(1):117-125

  Hydroxychloroquine in lupus or rheumatoid arthritis pregnancy and risk of major congenital malformations: a population-based cohort study

  Nguyen NV; Svenungsson E; Dominicus A; Altman M; Hellgren K; Simard JF; Arkema EV
• Article: BMJ OPEN. 2024;14(12):e090555

  Association between maternal systemic lupus erythematosus and infant infection: a population-based cohort study in Sweden

  Gernaat SAM; Simard JF; Altman M; Svenungsson E; Arkema EV
• Article: ALLERGY. 2024;79(12):3464-3474

  Biomarkers for a less invasive strategy to predict children with eosinophilic esophagitis

  Thulin H; Mansouri L; Altman M; Merid SK; Lundahl J; Nilsson C; Safholm J
• Article: BLOOD. 2024;144(22):2308-2318

  Diagnostic guidelines for familial hemophagocytic lymphohistiocytosis revisited

  Henter J-I; Sieni E; Eriksson J; Bergsten E; Myrberg IH; Canna SW; Coniglio ML; Cron RQ; Kernan KF; Kumar AR; Lehmberg K; Minoia F; Naqvi A; Ravelli A; Tang Y-M; Bottai M; Bryceson YT; Horne A; Jordan MB; Histiocyte S
• Journal article: JOURNAL OF IMMUNOLOGY. 2024;213(10):1452-1466

  NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children

  Dick JK; Sangala JA; Krishna VD; Khaimraj A; Hamel L; Erickson SM; Hicks D; Soigner Y; Covill LE; Johnson AK; Ehrhardt MJ; Ernste K; Brodin P; Koup RA; Khaitan A; Baehr C; Thielen BK; Henzler CM; Skipper C; Miller JS; Bryceson YT; Wu J; John CC; Panoskaltsis-Mortari A; Orioles A; Steiner ME; Cheeran MCJ; Pravetoni M; Hart GT
• Conference publication: 2024;:a217

  189 Genomic landscape and systemic immune states across pediatric solid tumors

  Zhao B; Chen Q; Tan Z; Hedberg G; Wang J; Gonzalez L; Mugabo C; Johansson A; Rodriguez L; Paez LP; James A; Chen Y; Mikes J; Barcenilla H; Wang C; Davis M; Carlson LM; Pal N; Blomgren K; Repsilber D; Lakshmikanth T; Kogner P; Ljungblad L; Brodin P
• Conference publication: 2024;:a41

  37 Systems-level immunity in children with solid tumors

  Chen Q; Zhao B; Tan Z; Hedberg G; Wang J; Gonzalez L; Mugabo C; Johnsson A; Paez LP; Rodriguez L; James A; Chen Y; Mikes J; Barcenilla H; Wang C; Davis M; Carlson LM; Pal N; Blomgren K; Repsilber D; Lakshmikanth T; Kogner P; Ljungblad L; Brodin P
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2024;12(11):2996-3013.e7

  Interleukin (IL)-1/IL-6-Inhibitor-Associated Drug Reaction With Eosinophilia and Systemic Symptoms (DReSS) in Systemic Inflammatory Illnesses

  Saper VE; Tian L; Verstegen RHJ; Conrad CK; Cidon M; Hopper RK; Kuo CS; Osoegawa K; Baszis K; Bingham CA; Ferguson I; Hahn T; Horne A; Isupova EA; Jones JT; Kasapcopur O; Klein-Gitelman MS; Kostik MM; Ozen S; Phadke O; Prahalad S; Randell RL; Sener S; Stingl C; Abdul-Aziz R; Akoghlanian S; Al Julandani D; Alvarez MB; Bader-Meunier B; Balay-Dustrude EE; Balboni I; Baxter SK; Berard RA; Bhattad S; Bolaria R; Boneparth A; Cassidy EA; Co DO; Collins KP; Dancey P; Dickinson AM; Edelheit BS; Espada G; Flanagan ER; Imundo LF; Jindal AK; Kim H-A; Klaus G; Lake C; Lapin WB; Lawson EF; Marmor I; Mombourquette J; Ogunjimi B; Olveda R; Ombrello MJ; Onel K; Poholek C; Ramanan AV; Ravelli A; Robinson AD; Rouster-Stevens K; Saad N; Schneider R; Selmanovic V; Pasic IS; Shenoi S; Shilo NR; Soep JB; Sura A; Taber SF; Tesher M; Tibaldi J; Torok KS; Tsin CM; Vasquez-Canizares N; Nunez DSV; Way EE; Whitehead B; Zemel LS; Sharma S; Fernandez-Vina MA; Mellins ED
• Article: ADVANCED SCIENCE. 2024;11(41):e2404510

  Molecular Profiling Defines Three Subtypes of Synovial Sarcoma

  Chen Y; Su Y; Cao X; Siavelis I; Leo IR; Zeng J; Tsagkozis P; Hesla AC; Papakonstantinou A; Liu X; Huang W-K; Zhao B; Haglund C; Ehnman M; Johansson H; Lin Y; Lehtioe J; Zhang Y; Larsson O; Li X; de Flon FH
• Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2024;45(1):31

  Normalized Interferon Signatures and Clinical Improvements by IFNAR1 Blocking Antibody (Anifrolumab) in Patients with Type I Interferonopathies

  Kretzschmar G; Paez LP; Tan Z; Wang J; Gonzalez L; Mugabo CH; Johnsson A; Chen Y; Mikes J; Lakshmikanth T; James A; Goldbach-Mansky R; Fischer M; Palmblad K; Alehashemi S; Horne A; Brodin P
• Article: SCIENTIFIC REPORTS. 2024;14(1):24512

  Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination

  Yalcinkaya A; Cavalli M; Aranda-Guillen M; Cederholm A; Guner A; Rietrae I; Mildner H; Behere A; Eriksson O; Gonzalez L; Mugabo CH; Johnsson A; Lakshmikanth T; Brodin P; Wadelius M; Hallberg P; Landegren N
• Journal article: JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY. 2024;13(Supplement_4):8-9

  Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C)

  Dick JK; Sangala JA; Krishna VD; Khaimraj A; Hamel L; Erickson SM; Hicks D; Soigner Y; Covill LE; Johnson AK; Ehrhardt MJ; Ernste K; Brodin P; Koup RA; Khaitan A; Baehr C; Thielen BK; Henzler CM; Skipper C; Miller JS; Bryceson YT; Wu J; John CC; Panoskaltsis-Mortari A; Orioles A; Steiner ME; Cheeran MC-J; Pravetoni M; Hart GT
• Corrigendum: NATURE. 2024;634(8033):e5

  Immune system adaptation during gender-affirming testosterone treatment (vol 633, pg 155, 2024)

  Lakshmikanth T; Consiglio C; Sardh F; Forlin R; Wang J; Tan Z; Barcenilla H; Rodriguez L; Sugrue J; Noori P; Ivanchenko M; Paez LP; Gonzalez L; Mugabo CH; Johnsson A; Ryberg H; Hallgren A; Pou C; Chen Y; Mikes J; James A; Dahlqvist P; Wahlberg J; Hagelin A; Holmberg M; Degerblad M; Isaksson M; Duffy D; Kampe O; Landegren N; Brodin P
• Journal article: NATURE REVIEWS IMMUNOLOGY. 2024;24(10):771

  Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy.

  James A; Brodin P
• Journal article: NATURE REVIEWS IMMUNOLOGY. 2024;24(10):697-698

  Immunological studies in trans-individuals undergoing gender affirming hormone therapy

  James A; Brodin P
• Article: NATURE. 2024;633(8028):155-164

  Immune system adaptation during gender-affirming testosterone treatment

  Lakshmikanth T; Consiglio C; Sardh F; Forlin R; Wang J; Tan Z; Barcenilla H; Rodriguez L; Sugrue J; Noori P; Ivanchenko M; Paez LP; Gonzalez L; Mugabo CH; Johnsson A; Ryberg H; Hallgren A; Pou C; Chen Y; Mikes J; James A; Dahlqvist P; Wahlberg J; Hagelin A; Holmberg M; Degerblad M; Isaksson M; Duffy D; Kampe O; Landegren N; Brodin P
• Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2024;221(9):e20231725

  SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency

  Chan Y-H; Lundberg V; Le Pen J; Yuan J; Lee D; Pinci F; Volpi S; Nakajima K; Bondet V; Akesson S; Khobrekar NV; Bodansky A; Du L; Melander T; Mariaggi A-A; Seeleuthner Y; Saleh TS; Chakravarty D; Marits P; Dobbs K; Vonlanthen S; Hennings V; Thorn K; Rinchai D; Bizien L; Chaldebas M; Sobh A; Ozcelik T; Keles S; AlKhater SA; Prando C; Meyts I; Wilson MR; Rosain J; Jouanguy E; Aubart M; Abel L; Mogensen TH; Pan-Hammarstrom Q; Gao D; Duffy D; Cobat A; Berg S; Notarangelo LD; Harschnitz O; Rice CM; Studer L; Casanova J-L; Ekwall O; Zhang S-Y
• Article: JOURNAL OF PHYSIOLOGY-LONDON. 2024;602(17):4171-4193

  Muscle memory in humans: evidence for myonuclear permanence and long-term transcriptional regulation after strength training

  Cumming KT; Reitzner SM; Hanslien M; Skilnand K; Seynnes OR; Horwath O; Psilander N; Sundberg CJ; Raastad T
• Article: RHEUMATOLOGY. 2024;63(SI2):si122-si128

  Comparison of EULAR/PRINTO/PReS Ankara 2008 and 2022 ACR/EULAR classification criteria for granulomatosis with polyangiitis in children.

  Kaya Akca U; Batu ED; Jelusic M; Calatroni M; Bakry R; Frkovic M; Vinšová N; Campos RT; Horne A; Caglayan S; Vaglio A; Moroni G; Emmi G; Ghiggeri GM; Koker O; Sinico RA; Kim S; Gagro A; Matucci-Cerinic C; Çomak E; Ekici Tekin Z; Arslanoglu Aydin E; Heshin-Bekenstein M; Acar BC; Gattorno M; Akman S; Sozeri B; Palmblad K; Al-Mayouf SM; Silva CA; Doležalová P; Merkel PA; Ozen S
• Article: BLOOD. 2024;144(8):873-887

  Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis

  Chiang SCC; Covill LE; Tesi B; Campbell TM; Schlums H; Nejati-Zendegani J; Mordrup K; Wood S; Theorell J; Sekine T; Al-Herz W; Akar HH; Belen FB; Chan MY; Devecioglu O; Aksu T; Ifversen M; Malinowska I; Sabel M; Unal E; Unal S; Introne WJ; Krzewski K; Gilmour KC; Ehl S; Ljunggren H-G; Nordenskjold M; Horne A; Henter J-I; Meeths M; Bryceson YT
• Doctoral thesis: 2024

  Multiomic analysis of T cells in response to cancers and microbes

  Tan, Ziyang
• Journal article: BMC MEDICINE. 2024;22(1):295

  Foetal gluten immunogenic peptides during pregnancy: a new determinant on the coeliac exposome

  Moreno MDL; Gonzalez-Rovira M; Martinez-Pancorbo C; Martin-Camean M; Najar-Moyano AM; Romero M; de la Hoz E; Lopez-Beltran C; Mellado E; Bartha JL; Brodin P; Rodriguez-Herrera A; Sainz-Bueno JA; Sousa C
• Article: BMC BIOLOGY. 2024;22(1):147

  DNA methylation of exercise-responsive genes differs between trained and untrained men

  Geiger C; Needhamsen M; Emanuelsson EB; Norrbom J; Steindorf K; Sundberg CJ; Reitzner SM; Lindholm ME
• Article: PHYSIOLOGICAL REPORTS. 2024;12(14):e16161

  Levels of circulating angiotensin-converting enzyme 2 are affected by acute exercise and correlate with markers of physical fitness in male athletes

  Reitzner SM; Emanuelsson EB; Sundberg CJ
• Article: DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY. 2024;66(7):902-909

  Circulating immune cell populations at rest and in response to acute endurance exercise in young adults with cerebral palsy

  Kruse A; Imery I; Corell L; Hjalmarsson E; Fernandez-Gonzalo R; Von Walden F; Reitzner SM
• Article: NATURE METHODS. 2024;21(6):1044-1052

  Molecular pixelation: spatial proteomics of single cells by sequencing

  Karlsson F; Kallas T; Thiagarajan D; Karlsson M; Schweitzer M; Navarro JF; Leijonancker L; Geny S; Pettersson E; Rhomberg-Kauert J; Larsson L; van Ooijen H; Petkov S; Gonzalez-Granillo M; Bunz J; Dahlberg J; Simonetti M; Sathe P; Brodin P; Barrio AM; Fredriksson S
• Conference publication: PHYSIOLOGY. 2024;39(S1):646

  Remodeling of the Human Skeletal Muscle Proteome Found After Long-Term Endurance Training but Not After Strength Training

  Emanuelsson E; Arif M; Reitzner S; Perez S; Lindholm M; Mardinoglu A; Daub C; Sundberg CJ; Chapman M
• Article: ACTA PHYSIOLOGICA. 2024;240(5):e14129

  The effect of neuromuscular electrical stimulation on the human skeletal muscle transcriptome.

  Flodin J; Reitzner SM; Emanuelsson EB; Sundberg CJ; Ackermann P
• Article: BIORXIV. 2024;:2024.04.16.589585

  Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C).

  Dick JK; Sangala JA; Krishna VD; Khaimraj A; Hamel L; Erickson SM; Hicks D; Soigner Y; Covill LE; Johnson A; Ehrhardt MJ; Ernste K; Brodin P; Koup RA; Khaitan A; Baehr C; Thielen BK; Henzler CM; Skipper C; Miller JS; Bryceson YT; Wu J; John CC; Panoskaltsis-Mortari A; Orioles A; Steiner ME; Cheeran MC-J; Pravetoni M; Hart GT
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;99(4):e13346

  Gut bacteria at 6 months of age are associated with immune cell status in 1-year-old children

  Nilsen M; Nygaard UC; Brodin P; Carlsen KCL; Fredheim C; Haugen G; Hedlin G; Jonassen CM; Jonsmoen ULA; Lakshmikanth T; Nordlund B; Olin A; Rehbinder EM; Skjerven HO; Snipen L; Staff AC; Soederhaell C; Vettukattil R; Rudi K
• Journal article: CANCER RESEARCH. 2024;84(6):6378

  Systems-level immunomonitoring in children with solid tumors

  Chen Q; Zhao B; Tan Z; Hedberg G; Wang J; Gonzalez L; Mugabo C; Johnsson A; Paez L; Rodriguez L; James A; Chen Y; Mikes J; Barcenilla H; Wang C; Davis MM; Carlson L-M; Pal N; Herold N; Blomgren K; Repsilber D; Lakshmikanth T; Kogner P; Ljungblad L; Brodin P
• Preprint: BIORXIV. 2024

  Cluster-free annotation of single cells using Earth mover’s distance-based classification

  Forlin R; Tajvar P; Wang N; Dimarogonas D; Brodin P
• Preprint: RESEARCH SQUARE. 2024

  Fetal-maternal interactions with gluten immunogenic peptides during pregnancy: a new determinant on the coeliac exposome

  Moreno MDL; González-Rovira M; Martínez-Pancorbo C; Martín-Cameán M; Nájar-Moyano AM; Romero M; Hoz E; López-Beltrán C; Mellado E; Bartha JL; Brodin P; Rodríguez-Herrera A; Sainz-Bueno JL; Sousa C
• Editorial comment: TRENDS IN MOLECULAR MEDICINE. 2024;30(3):200-201

  Immune system perturbations in patients with long COVID

  Rodriguez L; Brodin P
• Article: NPJ VACCINES. 2024;9(1):42

  No link between type I interferon autoantibody positivity and adverse reactions to COVID-19 vaccines

  Yalcinkaya A; Cavalli M; Cederholm A; Aranda-Guillen M; Behere A; Mildner H; Lakshmikanth T; Gonzalez L; Mugabo CH; Johnsson A; Ekwall O; Kampe O; Bensing S; Brodin P; Hallberg P; Wadelius M; Landegren N
• Article: NATURE. 2024;626(8000):827-835

  Smoking changes adaptive immunity with persistent effects

  Saint-Andre V; Charbit B; Biton A; Rouilly V; Posseme C; Bertrand A; Rotival M; Bergstedt J; Patin E; Albert ML; Quintana-Murci L; Duffy D
• Preprint: MEDRXIV. 2024

  Restrained memory CD8⁺T cell responses favors viral persistence and elevated IgG responses in patients with severe Long COVID

  Rodriguez L; Tan Z; Lakshmikanth T; Wang J; Barcenilla H; Swank Z; Zuo F; Abolhassani H; Pavlovitch-Bedzyk AJ; Wang C; Gonzalez L; Mugabo CH; Johnsson A; Chen Y; James A; Mikes J; Kleberg L; Sundling C; Björnson M; Bonnier MN; Ståhlberg M; Runold M; Björkander S; Melén E; Meyts I; Weyenbergh JV; Hammarström Q-P; Davis M; Walt D; Landegren N; COVID Human Genetic Effort; Aiuti A; Casari G; Casanova J-L; Jamoulle M; Bruchfeld J; Brodin P
• Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2024;221(2):e20231353

  Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children

  Bastard P; Gervais A; Taniguchi M; Saare L; Sarekannu K; Le Voyer T; Philippot Q; Rosain J; Bizien L; Asano T; Garcia-Prat M; Parra-Martinez A; Migaud M; Tsumura M; Conti F; Belot A; Riviere JG; Morio T; Tanaka J; Javouhey E; Haerynck F; Duvlis S; Ozcelik T; Keles S; Tandjaoui-Lambiotte Y; Escoda S; Husain M; Pan-Hammarstrom Q; Hammarstrom L; Ahlijah G; Haidar AA; Soudee C; Arseguel V; Abolhassani H; Sahanic S; Tancevski I; Nukui Y; Hayakawa S; Chrousos GP; Michos A; Tatsi E-B; Filippatos F; Rodriguez-Palmero A; Troya J; Tipu I; Meyts I; Roussel L; Ostrowski SR; Schidlowski L; Prando C; Condino-Neto A; Cheikh N; Bousfiha AA; El Bakkouri J; Peterson P; Pujol A; Levy R; Quartier P; Vinh DC; Boisson B; Beziat V; Zhang S-Y; Borghesi A; Pession A; Andreakos E; Marr N; Mentis A-FA; Mogensen TH; Rodriguez-Gallego C; Soler-Palacin P; Colobran R; Tillmann V; Neven B; Trouillet-Assant S; Brodin P; Abel L; Jouanguy E; Zhang Q; Martinon-Torres F; Salas A; Gomez-Carballa A; Gonzalez-Granado LI; Kisand K; Okada S; Puel A; Cobat A; Casanova J-L
• Article: PEDIATRIC RESEARCH. 2024;95(3):762-769

  Antisecretory factor in breastmilk is associated with reduced incidence of sepsis in preterm infants

  Gustafsson A; Johansson E; Henckel E; Olin A; Rodriguez L; Brodin P; Lange S; Bohlin K
• Article: CYTOMETRY PART B-CLINICAL CYTOMETRY. 2024;105(2):124-138

  Standardized high-dimensional spectral cytometry protocol and panels for whole blood immune phenotyping in clinical and translational studies.

  Dott T; Culina S; Chemali R; Mansour CA; Dubois F; Jagla B; Doisne JM; Rogge L; Huetz F; Jönsson F; Commere P-H; Di Santo J; Terrier B; Quintana-Murci L; Duffy D; Hasan M; Milieu Intérieur Consortium
• Conference publication: 2024;:a1.1-a1a1

  1 The effect of neuromuscular electrical stimulation on human skeletal muscle

  Flodin J; Reitzner S; Emanuelsson E; Sundberg C-J; Ackermann P
• Article: BMJ-BRITISH MEDICAL JOURNAL. 2024;384:e075630

  Neurological development in children born moderately or late preterm: national cohort study

  Mitha A; Chen R; Razaz N; Johansson S; Stephansson O; Altman M; Bolk J
• Article: ISCIENCE. 2024;27(1):108638

  Remodeling of the human skeletal muscle proteome found after long-term endurance training but not after strength training

  Emanuelsson EB; Arif M; Reitzner SM; Perez S; Lindholm ME; Mardinoglu A; Daub C; Sundberg CJ; Chapman MA
• Article: SCIENCE. 2024;383(6680):eadg7942

  Persistent complement dysregulation with signs of thromboinflammation in active Long Covid

  Cervia-Hasler C; Brueningk SC; Hoch T; Fan B; Muzio G; Thompson RC; Ceglarek L; Meledin R; Westermann P; Emmenegger M; Taeschler P; Zurbuchen Y; Pons M; Menges D; Ballouz T; Cervia-Hasler S; Adamo S; Merad M; Charney AW; Puhan M; Brodin P; Nilsson J; Aguzzi A; Raeber ME; Messner CB; Beckmann ND; Borgwardt K; Boyman O
• Preprint: BIORXIV. 2024

  High-throughput analysis of membrane fluidity unveils a hidden dimension in immune cell states

  Andronico L; Jiang Y; Carannante V; Iskrak S; Sandoz P; Mikes J; Klymchenko A; Buggert M; Österborg A; Önfelt B; Brodin P; Sezgin E
• Corrigendum: GENOME MEDICINE. 2024;16(1):6

  Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 (vol 15, 22, 2023)

  Matuozzo D; Talouarn E; Marchal A; Zhang P; Manry J; Seeleuthner Y; Zhang Y; Bolze A; Chaldebas M; Milisavljevic B; Gervais A; Bastard P; Asano T; Bizien L; Barzaghi F; Abolhassani H; Tayoun AA; Aiuti A; Darazam IA; Allende LM; Alonso-Arias R; Arias AA; Aytekin G; Bergman P; Bondesan S; Bryceson YT; Bustos IG; Cabrera-Marante O; Carcel S; Carrera P; Casari G; Chaibi K; Colobran R; Condino-Neto A; Covill LE; Delmonte OM; Zein LE; Flores C; Gregersen PK; Gut M; Haerynck F; Halwani R; Hancerli S; Hammarstroem L; Hatipoglu N; Karbuz A; Keles S; Kyheng C; Leon-Lopez R; Franco JL; Mansouri D; Martinez-Picado J; Akcan OM; Migeotte I; Morange P-E; Morelle G; Martin-Nalda A; Novelli G; Novelli A; Ozcelik T; Palabiyik F; Pan-Hammarstroem Q; de Diego RP; Planas-Serra L; Pleguezuelo DE; Prando C; Pujol A; Reyes LF; Riviere JG; Rodriguez-Gallego C; Rojas J; Rovere-Querini P; Schlueter A; Shahrooei M; Sobh A; Soler-Palacin P; Tandjaoui-Lambiotte Y; Tipu I; Tresoldi C; Troya J; van de Beek D; Zatz M; Zawadzki P; Al-Muhsen SZ; Alosaimi MF; Alsohime FM; Baris-Feldman H; Butte MJ; Constantinescu SN; Cooper MA; Dalgard CL; Fellay J; Heath JR; Lau Y-L; Lifton RP; Maniatis T; Mogensen TH; von Bernuth H; Lermine A; Vidaud M; Boland A; Deleuze J-F; Nussbaum R; Kahn-Kirby A; Mentre F; Tubiana S; Gorochov G; Tubach F; Hausfater P; Meyts I; Zhang S-Y; Puel A; Notarangelo LD; Boisson-Dupuis S; Su HC; Boisson B; Jouanguy E; Casanova J-L; Zhang Q; Abel L; Cobat A
• Review: NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY. 2024;21(1):35-45

  The maternal gut microbiome in pregnancy: implications for the developing immune system

  Koren O; Konnikova L; Brodin P; Mysorekar IU; Collado MC
• Article: MOLECULAR METABOLISM. 2024;79:101857

  Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise- A systems biology approach

  Reitzner SM; Emanuelsson EB; Arif M; Kaczkowski B; Kwon ATJ; Mardinoglu A; Arner E; Chapman MA; Sundberg CJ
• Article: SCIENCE IMMUNOLOGY. 2023;8(90):eabp8966

  Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs

  Bastard P; Vazquez S; Liu J; Laurie MT; Wang CY; Gervais A; Le Voyer T; Bizien L; Zamecnik C; Philippot Q; Rosain J; Catherinot E; Willmore A; Mitchell AM; Bair R; Garcon P; Kenney H; Fekkar A; Salagianni M; Poulakou G; Siouti E; Sahanic S; Tancevski I; Weiss G; Nagl L; Manry J; Duvlis S; Arroyo-Sanchez D; Paz Artal E; Rubio L; Perani C; Bezzi M; Sottini A; Quaresima V; Roussel L; Vinh DC; Felipe Reyes L; Garzaro M; Hatipoglu N; Boutboul D; Tandjaoui-Lambiotte Y; Borghesi A; Aliberti A; Cassaniti I; Venet F; Monneret G; Halwani R; Sharif-Askari NS; Danielson J; Burrel S; Morbieu C; Stepanovskyy Y; Bondarenko A; Volokha A; Boyarchuk O; Gagro A; Neuville M; Neven B; Keles S; Hernu R; Bal A; Novelli A; Novelli G; Saker K; Ailioaie O; Antoli A; Jeziorski E; Rocamora-Blanch G; Teixeira C; Delaunay C; Lhuillier M; Le Turnier P; Zhang Y; Mahevas M; Pan-Hammarstrom Q; Abolhassani H; Bompoil T; Dorgham K; Group FCS; Gorochov G; Laouenan C; Rodriguez-Gallego C; Ng LFP; Renia L; Pujol A; Belot A; Raffi F; Allende LM; Martinez-Picado J; Ozcelik T; Keles S; Imberti L; Notarangelo LD; Troya J; Solanich X; Zhang S-Y; Puel A; Wilson MR; Trouillet-Assants S; Abe L; Jouanguy E; Ye CJ; Cobat A; Thompson LM; Andreakos E; Zhang Q; Anderson MS; Casanova J-L; DeRisi JL
• Article: GUT MICROBES. 2023;15(2):2287618

  Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response.

  Delavy M; Sertour N; Patin E; Le Chatelier E; Cole N; Dubois F; Xie Z; Saint-André V; Manichanh C; Walker AW; Quintana-Murci L; Duffy D; d'Enfert C; Bougnoux M-E; Consortium MI
• Conference publication: 2023 62ND IEEE CONFERENCE ON DECISION AND CONTROL, CDC. 2023;:715-720

  Modelling Pathogen Response of the Human Immune System in a Reduced State Space

  Tajvar P; Forlin R; Brodin P; Dimarogonas DV
• Article: ADVANCED SCIENCE. 2023;10(35):e2300123

  Identification and Characterization of CD8⁺CD27⁺CXCR3^- T Cell Dysregulation and Progression-Associated Biomarkers in Systemic Lupus Erythematosus

  Zhang L; Du F; Jin Q; Sun L; Wang B; Tan Z; Meng X; Huang B; Zhan Y; Su W; Song R; Wu C; Chen L; Chen X; Ding X
• Article: NATURE. 2023;623(7988):803-813

  Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

  Le Voyer T; Parent AV; Liu X; Cederholm A; Gervais A; Rosain J; Nguyen T; Lorenzo MP; Rackaityte E; Rinchai D; Zhang P; Bizien L; Hancioglu G; Ghillani-Dalbin P; Charuel J-L; Philippot Q; Gueye MS; Renkilaraj MRLM; Ogishi M; Soudee C; Migaud M; Rozenberg F; Momenilandi M; Riller Q; Imberti L; Delmonte OM; Mueller G; Keller B; Orrego J; Gallego WAF; Rubin T; Emiroglu M; Parvaneh N; Eriksson D; Aranda-Guillen M; Berrios DI; Vong L; Katelaris CH; Mustillo P; Raedler J; Bohlen J; Celik JB; Astudillo C; Winter S; McLean C; Guffroy A; DeRisi JL; Yu D; Miller C; Feng Y; Guichard A; Beziat V; Bustamante J; Pan-Hammarstrom Q; Zhang Y; Rosen LB; Holland SM; Bosticardo M; Kenney H; Castagnoli R; Slade CA; Boztug K; Mahlaoui N; Latour S; Abraham RS; Lougaris V; Hauck F; Sediva A; Atschekzei F; Sogkas G; Poli MC; Slatter MA; Palterer B; Keller MD; Pinzon-Charry A; Sullivan A; Droney L; Suan D; Wong M; Kane A; Hu H; Ma C; Grombirikova H; Ciznar P; Dalal I; Aladjidi N; Hie M; Lazaro E; Franco J; Keles S; Malphettes M; Pasquet M; Maccari ME; Meinhardt A; Ikinciogullari A; Shahrooei M; Celmeli F; Frosk P; Goodnow CC; Gray PE; Belot A; Kuehn HS; Rosenzweig SD; Miyara M; Licciardi F; Servettaz A; Barlogis V; Le Guenno G; Herrmann V-M; Kuijpers T; Ducoux G; Sarrot-Reynauld F; Schuetz C; Cunningham-Rundles C; Rieux-Laucat F; Tangye SG; Sobacchi C; Doffinger R; Warnatz K; Grimbacher B; Fieschi C; Berteloot L; Bryant VL; Assant ST; Su H; Neven B; Abel L; Zhang Q; Boisson B; Cobat A; Jouanguy E; Kampe O; Bastard P; Roifman CM; Landegren N; Notarangelo LD; Anderson MS; Casanova J-L; Puel A
• Preprint: MEDRXIV. 2023

  Demographic and genetic factors shape the epitope specificity of the human antibody repertoire against viruses

  Olin A; Jaquaniello A; Roux M; Tan Z; Pou C; Dubois F; Charbit B; Liu D; Bloch E; Clave E; Araujo IL; Toubert A; White M; Rotival M; Brodin P; Duffy D; Quintana-Murci L; Patin E; Consortium MI
• Journal article: CIRCULATION. 2023;148:a16646

  Evidence of Protein Dysregulation in Patients With Post-Acute COVID-19 Syndrome With- and Without Postural Orthostatic Tachycardia Syndrome

  Zhao A; Mahdi A; Fredengren E; Fedorowski A; Braunschweig F; Brodin P; Nygren-Bonnier M; Runold M; Bruchfeld J
• Doctoral thesis: 2023

  Immune variation in infectious disease and during development early in life

  Rodriguez, Lucie Solène Tiaré
• Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(10):1714-1732

  The 2022 EULAR/ACR Points to Consider at the Early Stages of Diagnosis and Management of Suspected Haemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome (HLH/MAS)

  Shakoory B; Geerlinks A; Wilejto M; Kernan K; Hines M; Romano M; Piskin D; Ravelli A; Sinha R; Aletaha D; Allen C; Bassiri H; Behrens EM; Carcillo J; Carl L; Chatham W; Cohen JI; Cron RQ; Drewniak E; Grom AA; Henderson LA; Horne A; Jordan MB; Nichols KE; Schulert G; Vastert S; Demirkaya E; Goldbach-Mansky R; de Benedetti F; Marsh RA; Canna SW
• Review: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(10):1271-1285

  The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS)

  Shakoory B; Geerlinks A; Wilejto M; Kernan K; Hines M; Romano M; Piskin D; Ravelli A; Sinha R; Aletaha D; Allen C; Bassiri H; Behrens EM; Carcillo J; Carl L; Chatham W; Cohen JI; Cron RQ; Drewniak E; Grom AA; Henderson LA; Horne A; Jordan MB; Nichols KE; Schulert G; Vastert S; Demirkaya E; Goldbach-Mansky R; de Benedetti F; Marsh RA; Canna SW
• Review: SEMINARS IN IMMUNOLOGY. 2023;69:101794

  Immune responses to SARS-CoV-2 infection and vaccination in children

  Brodin P
• Article: ACTA PHYSIOLOGICA. 2023;239(1):e13982

  FiNuTyper: Design and validation of an automated deep learning-based platform for simultaneous fiber and nucleus type analysis in human skeletal muscle

  Lundquist A; Lazar E; Han NS; Emanuelsson EB; Reitzner SM; Chapman MA; Shirokova V; Alkass K; Druid H; Petri S; Sundberg CJ; Bergmann O
• Journal article: JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2023;159:104065

  Immune system adaptation during gender-affirming testosterone treatment

  Consiglio C; Tadepally L; Sardh F; Forlin R; Wang J; Tan Z; Barcenilla H; Rodriguez L; Sugrue J; Noori P; Paez LP; Gonzalez L; Mugabo CH; Johnsson A; Hallgren A; Pou C; Chen Y; Mikes J; James A; Dahlqvist P; Wahlberg J; Hagelin A; Holmberg M; Degerblad M; Isaksson M; Duffy D; Kampe O; Landegren N; Brodin P
• Article: ISCIENCE. 2023;26(8):107422

  Integrated analysis of whole blood oxylipin and cytokine responses after bacterial, viral, and T cell stimulation reveals new immune networks.

  Villain E; Chanson A; Mainka M; Kampschulte N; Le Faouder P; Bertrand-Michel J; Brandolini-Bulon M; Charbit B; Musvosvi M; Bilek N; Scriba TJ; Quintana-Murci L; Schebb NH; Duffy D; Gladine C; Milieu Interieur Consortium
• Review: TRENDS IN IMMUNOLOGY. 2023;44(8):577-584

  Making human immune systems more interpretable through systems immunology

  Forlin R; James A; Brodin P
• Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2023;58(7):709-717

  Identification of irritable bowel syndrome in the Swedish National Patient Register: a validation study

  Tornkvist NT; Backman A-S; Linder M; Altman M; Simren M; Olen O; Tornblom H
• Article: IMMUNITY. 2023;56(6):1255-1268.e5

  Age-dependent differences in efferocytosis determine the outcome of opsonophagocytic protection from invasive pathogens

  Bee GCW; Lokken-Toyli KL; Yeung ST; Rodriguez L; Zangari T; Anderson EE; Ghosh S; Rothlin CV; Brodin P; Khanna KM; Weiser JN
• Preprint: BIORXIV. 2023

  Scalablein-vitroimmunostimulation of human blood for in-depth profiling of acute immune response effects

  Reitzner SM; Brodin P; Mikeš J
• Preprint: BIORXIV. 2023

  Molecular Pixelation: Single cell spatial proteomics by sequencing

  Karlsson F; Kallas T; Thiagarajan D; Karlsson M; Schweitzer M; Navarro JF; Leijonancker L; Geny S; Pettersson E; Rhomberg-Kauert J; Granillo MG; Bunz J; Dahlberg J; Simonetti M; Sathe P; Brodin P; Barrio AM; Fredriksson S
• Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2023;41(16_suppl):3110

  First-in-human (FIH) phase I dose escalation study (part A) of the first oral allosteric modulator of phosphoinositide 3-kinase inhibitor delta (PI3Kδ) roginolisib in patients with advanced cancer and dose confirmation in uveal melanoma (part B).

  Di Giacomo AM; Santangelo F; Amato G; Simonetti E; Graham J; Lahn MMF; Di Conza G; Hammett T; Zorrilla R; Durini M; Tan Z; Tadepally L; Brodin P; Occhipinti M; Simonelli M; Carlo-Stella C; Santoro A; Spiliopoulou P; Evans TRJ; Maio M
• Article: ACR OPEN RHEUMATOLOGY. 2023;5(5):277-284

  Risk of Psychiatric Disorders in Juvenile Idiopathic Arthritis: Population- and Sibling-Controlled Cohort and Cross-Sectional Analyses

  Delcoigne B; Horne A; Askling J; Askling J
• Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2023;220(5):e20220170

  Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia

  Garcia-Garcia A; de Diego RP; Flores C; Rinchai D; Sole-Violan J; Deya-Martinez A; Garcia-Solis B; Lorenzo-Salazar JM; Hernandez-Brito E; Lanz A-L; Moens L; Bucciol G; Almuqamam M; Domachowske J; Colino E; Santos-Perez JL; Marco F; Pignata C; Bousfiha A; Turvey S; Bauer S; Haerynck F; Ocejo-Vinyals JG; Lendinez F; Prader S; Naumann-Bartsch N; Pachlopnik Schmid J; Biggs C; Hildebrand K; Dreesman A; Cardenes MA; Ailal F; Benhsaien I; Giardino G; Molina-Fuentes A; Fortuny C; Madhavarapu S; Conway D; Prando C; Schidlowski L; Alvarez MTMDS; Alfaro R; de Castro FR; Meyts I; Hauck F; Puel A; Bastard P; Boisson B; Jouanguy E; Abel L; Cobat A; Zhang Q; Casanova J-L; Alsina L; Rodriguez-Gallego C
• Article: PAEDIATRIC AND PERINATAL EPIDEMIOLOGY. 2023;37(4):276-286

  The Stockholm-Gotland perinatal cohort-A population-based cohort including longitudinal data throughout pregnancy and the postpartum period

  Johansson K; Granfors M; Petersson G; Bolk J; Altman M; Cnattingius S; Liu X; Sandstrom A; Stephansson O
• Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(Supplement_1):233.07

  Immune system perturbations in patients with severe long COVID

  Rodriguez L; Tan Z; Lakshmikanth T; Wang J; Barcenilla H; Gonzalez L; Mugabo C; Johnsson A; Chen Y; Mikes J; Landegren N; Runold M; Bruchfeld J; Brodin P
• Article: LANCET REGIONAL HEALTH-EUROPE. 2023;28:100608

  Ambient air pollution exposure linked to long COVID among young adults: a nested survey in a population-based cohort in Sweden

  Yu Z; Ekstrom S; Bellander T; Ljungman P; Pershagen G; Eneroth K; Kull I; Bergstrom A; Georgelis A; Stafoggia M; Gruzieva O; Melen E
• Preprint: BIORXIV. 2023

  Molecular profiling of high-level athlete skeletal muscle after acute exercise – a systems biology approach

  Reitzner S; Emanuelsson E; Arif M; Kaczkowski B; Kwon ATJ; Mardinoglu A; Arner E; Chapman M; Sundberg CJ
• Article: GENOME MEDICINE. 2023;15(1):22

  Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

  Matuozzo D; Talouarn E; Marchal A; Zhang P; Manry J; Seeleuthner Y; Zhang Y; Bolze A; Chaldebas M; Milisavljevic B; Gervais A; Bastard P; Asano T; Bizien L; Barzaghi F; Abolhassani H; Abou Tayoun A; Aiuti A; Alavi Darazam I; Allende LM; Alonso-Arias R; Arias AA; Aytekin G; Bergman P; Bondesan S; Bryceson YT; Bustos IG; Cabrera-Marante O; Carcel S; Carrera P; Casari G; Chaibi K; Colobran R; Condino-Neto A; Covill LE; Delmonte OM; El Zein L; Flores C; Gregersen PK; Gut M; Haerynck F; Halwani R; Hancerli S; Hammarstroem L; Hatipoglu N; Karbuz A; Keles S; Kyheng C; Leon-Lopez R; Franco JL; Mansouri D; Martinez-Picado J; Metin Akcan O; Migeotte I; Morange P-E; Morelle G; Martin-Nalda A; Novelli G; Novelli A; Ozcelik T; Palabiyik F; Pan-Hammarstroem Q; de Diego RP; Planas-Serra L; Pleguezuelo DE; Prando C; Pujol A; Reyes LF; Riviere JG; Rodriguez-Gallego C; Rojas J; Rovere-Querini P; Schlueter A; Shahrooei M; Sobh A; Soler-Palacin P; Tandjaoui-Lambiotte Y; Tipu I; Tresoldi C; Troya J; van de Beek D; Zatz M; Zawadzki P; Al-Muhsen SZ; Alosaimi MF; Alsohime FM; Baris-Feldman H; Butte MJ; Constantinescu SN; Cooper MA; Dalgard CL; Fellay J; Heath JR; Lau Y-L; Lifton RP; Maniatis T; Mogensen TH; von Bernuth H; Lermine A; Vidaud M; Boland A; Deleuze J-F; Nussbaum R; Kahn-Kirby A; Mentre F; Tubiana S; Gorochov G; Tubach F; Hausfater P; Effort COVIDHG; Meyts I; Zhang S-Y; Puel A; Notarangelo LD; Boisson-Dupuis S; Su HC; Boisson B; Jouanguy E; Casanova J-L; Zhang Q; Abel L; Cobat A
• Article: LANCET RHEUMATOLOGY. 2023;5(4):e184-e199

  Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study

  Channon-Wells S; Vito O; McArdle AJ; Seaby EG; Patel H; Shah P; Pazukhina E; Wilson C; Broderick C; D'Souza G; Keren I; Nijman RG; Tremoulet A; Munblit D; Ulloa-Gutierrez R; Carter MJ; Ramnarayan P; De T; Hoggart C; Whittaker E; Herberg JA; Kaforou M; Cunnington AJ; Blyuss O; Levin M
• Review: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;151(4):832-840

  Inherited and acquired errors of type I interferon immunity govern susceptibility to COVID-19 and multisystem inflammatory syndrome in children.

  Bucciol G; COVID Human Genetic Effort; Meyts I
• Article: ACTA PAEDIATRICA. 2023;112(4):667-674

  Low Apgar score and need for resuscitation increased the probability of receiving therapeutic hypothermia more strongly than acidosis at birth

  Lagerstrom I; Daugeliene D; Bolk J; Cnattingius S; Skiold B; Altman M; Johansson S
• Review: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;151(4):818-831

  Impact of SARS-CoV-2 infection and COVID-19 on patients with inborn errors of immunity

  Tangye SG
• Preprint: BIORXIV. 2023

  Circulating immune cell populations at rest and in response to acute endurance exercise in young adults with cerebral palsy

  Kruse A; Imery I; Corell L; Hjalmarsson E; Fernandez-Gonzalo R; von Walden F; Reitzner S
• Editorial comment: SCIENCE. 2023;379(6632):538-539

  Exaggerated responses to a virus long gone Multisystem inflammatory syndrome in children is caused by abnormal cell activation

  Brodin P
• Article: SCIENCE. 2023;379(6632):1-20

  Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children

  Lee D; Le Pen J; Yatim A; Dong B; Aquino Y; Ogishi M; Pescarmona R; Talouarn E; Rinchai D; Zhang P; Perret M; Liu Z; Jordan I; Bozdemir SE; Bayhan GI; Beaufils C; Bizien L; Bisiaux A; Lei W; Hasan M; Chen J; Gaughan C; Asthana A; Libri V; Luna JM; Jaffre F; Hoffmann HH; Michailidis E; Moreews M; Seeleuthner Y; Bilguvar K; Mane S; Flores C; Zhang Y; Arias AA; Bailey R; Schluter A; Milisavljevic B; Bigio B; Le Voyer T; Materna M; Gervais A; Moncada-Velez M; Pala F; Lazarov T; Levy R; Neehus A-L; Rosain J; Peel J; Chan Y-H; Morin M-P; Pino-Ramirez RM; Belkaya S; Lorenzo L; Anton J; Delafontaine S; Toubiana J; Bajolle F; Fumado V; DeDiego ML; Fidouh N; Rozenberg F; Perez-Tur J; Chen S; Evans T; Geissmann F; Lebon P; Weiss SR; Bonnet D; Duval X; Pan-Hammarstrom Q; Planas AM; Meyts I; Haerynck F; Pujol A; Sancho-Shimizu V; Dalgard CL; Bustamante J; Puel A; Boisson-Dupuis S; Boisson B; Maniatis T; Zhang Q; Bastard P; Notarangelo L; Beziat V; de Diego RP; Rodriguez-Gallego C; Su HC; Lifton RP; Jouanguy E; Cobat A; Alsina L; Keles S; Haddad E; Abel L; Belot A; Quintana-Murci L; Rice CM; Silverman RH; Zhang S-Y; Casanova J-L
• Article: OXFORD OPEN IMMUNOLOGY. 2023;4(1):iqad003

  Achieving symptom relief in patients with myalgic encephalomyelitis by targeting the neuro-immune interface and optimizing disease tolerance.

  Rodriguez L; Pou C; Lakshmikanth T; Zhang J; Mugabo CH; Wang J; Mikes J; Olin A; Chen Y; Rorbach J; Juto J-E; Li TQ; Julin P; Brodin P
• Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2023;41(16)

  First-in-human (FIH) phase I dose escalation study (part A) of the first oral allosteric modulator of phosphoinositide 3-kinase inhibitor delta (PI3Kδ) roginolisib in patients with advanced cancer and dose confirmation in uveal melanoma (part B).

  Di Giacomo AM; Santangelo F; Amato G; Simonetti E; Graham J; Lahn MMF; Di Conza G; Hammett T; Zorrilla R; Durini M; Tan Z; Tadepally L; Brodin P; Occhipinti M; Simonelli M; Carlo-Stella C; Santoro A; Spiliopoulou P; Evans TRJ; Maio M
• Conference publication: ANNALS OF NUTRITION AND METABOLISM. 2023;79:340

  The effects of 20-week exercise on whole-blood genome-wide DNA methylation profile in children with overweight/obesity

  Anguita-Ruiz A; Plaza-Florido A; Altmae S; Aguilera CM; Reitzner SM; Sundberg CJ; Ortega FB
• Article: PLOS ONE. 2023;18(12):e0295838

  Anakinra or tocilizumab in patients admitted to hospital with severe covid-19 at high risk of deterioration (IMMCoVA): A randomized, controlled, open-label trial

  Sunden-Cullberg J; Chen P; Habel H; Skorup P; Janols H; Rasmuson J; Niward K; Balkhed AO; Chatzidionysiou K; Asgeirsson H; Blennow O; Parke A; Svensson A-K; Muvva JR; Ljunggren H-G; Horne A-C; Aden U; Henter J-I; Sonnerborg A; Vesterbacka J; Nowak P; Lampa J
• Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)

  Immune system perturbations in patients with severe long COVID

  Rodriguez L; Tan Z; Lakshmikanth T; Wang J; Barcenilla H; Gonzalez L; Mugabo C; Johnsson A; Chen Y; Mikes J; Landegren N; Runold M; Bruchfeld J; Brodin P
• Conference publication: ARTHRITIS & RHEUMATOLOGY. 2023;75:4913-4915

  Anifrolumab Normalizes the Type I Interferon Signature in a Cohort of Patients with Type I Interferonopathies

  Alehashemi S; Baumgardner A; Shakoory B; de Jesus AA; Park S; Uss K; Robles MP; Palmblad K; Horne A; Brodin P; Akoghlanian S; Abraham R; Mustillo P; Barillas-Arias L; Heras A; Muskardin TW; Lawrence MG; Mannem HC; Nolan BE; Canna S; Reinhardt A; Binstadt B; Goldbach-Mansky R
• Review: CAMBRIDGE PRISMS: PRECISION MEDICINE. 2023;1:e25

  Making inroads to precision medicine for the treatment of autoimmune diseases: Harnessing genomic studies to better diagnose and treat complex disorders.

  Baglaenko Y; Wagner C; Bhoj VG; Brodin P; Gershwin ME; Graham D; Invernizzi P; Kidd KK; Korsunsky I; Levy M; Mammen AL; Nizet V; Ramirez-Valle F; Stites EC; Williams MS; Wilson M; Rose NR; Ladd V; Sirota M
• Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(1):136-150

  Three Adult Cases of STAT1 Gain-of-Function with Chronic Mucocutaneous Candidiasis Treated with JAK Inhibitors

  Borgstrom EW; Edvinsson M; Perez LP; Norlin AC; Enoksson SL; Hansen S; Fasth A; Friman V; Kampe O; Mansson R; Estupinan HY; Qing W; Tan Z; Lakshmikanth T; Smith CIE; Brodin P; Bergman P
• Preprint: BIORXIV. 2022

  FiNuTyper: an automated deep learning-based platform for simultaneous fiber and nucleus type analysis in human skeletal muscle

  Lundquist A; Lázár E; Han NS; Emanuelsson E; Reitzner S; Chapman M; Alkass K; Druid H; Petri S; Sundberg CJ; Bergmann O
• Editorial comment: BMJ-BRITISH MEDICAL JOURNAL. 2022;379:o2750

  The challenges of doing paediatric research during the first year of the covid-19 pandemic

  Buonsenso D; Roland D; Yock-Corrales A; Gonzalez-Dambrauskas S; Brodin P; Santiago-Garcia B; Soriano-Arandes A; Koenraads M; De Luca D; Whittaker E
• Article: CELL REPORTS MEDICINE. 2022;3(11):100804

  Enhanced TLR3 responsiveness in hepatitis C virus resistant women from the Irish anti-D cohort

  Sugrue JA; Posseme C; Tan Z; Pou C; Charbit B; Bondet V; Bourke NM; Brodin P; Duffy D; O'Farrelly C
• Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2022;219(11):e20220514

  Autoantibodies against type I IFNs in patients with critical influenza pneumonia

  Zhang Q; Pizzorno A; Miorin L; Bastard P; Gervais A; Le Voyer T; Bizien L; Manry J; Rosain J; Philippot Q; Goavec K; Padey B; Cupic A; Laurent E; Saker K; Vanker M; Saerekannu K; Garcia-Salum T; Ferres M; Le Corre N; Sanchez-Cespedes J; Balsera-Manzanero M; Carratala J; Retamar-Gentil P; Abelenda-Alonso G; Valiente A; Tiberghien P; Zins M; Debette S; Meyts I; Haerynck F; Castagnoli R; Notarangelo LD; Gonzalez-Granado LI; Dominguez-Pinilla N; Andreakos E; Triantafyllia V; Rodriguez-Gallego C; Sole-Violan J; Ruiz-Hernandez JJ; Rodriguez de Castro F; Ferreres J; Briones M; Wauters J; Vanderbeke L; Feys S; Kuo C-Y; Lei W-T; Ku C-L; Tal G; Etzioni A; Hanna S; Fournet T; Casalegno J-S; Queromes G; Argaud L; Javouhey E; Rosa-Calatrava M; Cordero E; Aydillo T; Medina RA; Kisand K; Puel A; Jouanguy E; Abel L; Cobat A; Trouillet-Assant S; Garcia-Sastre A; Casanova J-L
• Article: NATURE COMMUNICATIONS. 2022;13(1):5895

  The immune factors driving DNA methylation variation in human blood

  Bergstedt J; Azzou SAK; Tsuo K; Jaquaniello A; Urrutia A; Rotival M; Lin DTS; MacIsaac JL; Kobor MS; Albert ML; Duffy D; Patin E; Quintana-Murci L
• Editorial comment: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(7):1354-1359

  Decoding the Human Genetic and Immunological Basis of COVID-19 mRNA Vaccine-Induced Myocarditis

  Bolze A; Mogensen TH; Zhang S-Y; Abel L; Andreakos E; Arkin LM; Borghesi A; Brodin P; Hagin D; Novelli G; Okada S; Peter J; Renia L; Severe K; Tiberghien P; Vinh DC; Cirulli ET; Casanova J-L; Hsieh EWY
• Article: MOLECULAR ONCOLOGY. 2022;16(19):3452-3464

  Prostate cancer disease recurrence after radical prostatectomy is associated with HLA type and local cytomegalovirus immunity

  Classon J; Zamboni M; Engblom C; Alkass K; Mantovani G; Pou C; Nkulikiyimfura D; Brodin P; Druid H; Mold J; Frisen J
• Article: BMC PEDIATRICS. 2022;22(1):565

  Transplantation of maternal intestinal flora to the newborn after elective cesarean section (SECFLOR): study protocol for a double blinded randomized controlled trial

  Carpen N; Brodin P; de Vos WM; Salonen A; Kolho K-L; Andersson S; Helve O
• Journal article: CLINICAL CANCER RESEARCH. 2022;28(18_Supplement):a039

  Abstract A039: IGFBP5 is induced by tumor-suppressive naïve stromal cells and regulates GAS2-associated apoptosis in rhabdomyosarcoma

  Ehnman M; Katkhada K; Meng LZ; Zhang Y; Zhao B; Tong S; Kallai A; Östman A; Tobin N
• Article: SCIENTIFIC REPORTS. 2022;12(1):14937

  Selective transfer of maternal antibodies in preterm and fullterm children

  Dolatshahi S; Butler AL; Pou C; Henckel E; Bernhardsson AK; Gustafsson A; Bohlin K; Shin SA; Lauffenburger DA; Brodin P; Alter G
• Article: ACR OPEN RHEUMATOLOGY. 2022;4(9):804-810

  Treatment of Multisystem Inflammatory Syndrome in Children: Understanding Differences in Results of Comparative Effectiveness Studies.

  Melgar M; Seaby EG; McArdle AJ; Young CC; Campbell AP; Murray NL; Patel MM; Levin M; Randolph AG; Son MBF; BATS Consortium and the Overcoming COVID-19 Invest
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9S):392-393

  Skeletal Muscle Proteomics Comparison Between Long-term Trained And Untrained Men And Women

  Chapman M; Emanuelsson E; Arif M; Lakhia Z; Reitzner S; Mardinoglu A; Sundberg CJ
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9S):628

  Metabolomic Response To Acute Endurance And Resistance Exercise In Life-long Trained Athletes And Untrained Individuals

  Reitzner SM; Arif M; Emanuelsson E; Chapman M; Mardinoglu A; Sundberg CJ
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9S):389

  MRI Characterization Of Skeletal Muscle Size And Fatty Infiltration In Long-term Trained And Untrained Individuals

  Emanuelsson EB; Berry D; Reitzner SM; Arif M; Mardinoglu A; Gustafsson T; Ward S; Sundberg CJ; Chapman MA
• Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2022;219(8):e20220131

  Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

  Zhang Q; Matuozzo D; Le Pen J; Lee D; Moens L; Asano T; Bohlen J; Liu Z; Moncada-Velez M; Kendir-Demirkol Y; Jing H; Bizien L; Marchal A; Abolhassani H; Delafontaine S; Bucciol G; Bayhan GI; Keles S; Kiykim A; Hancerli S; Haerynck F; Florkin B; Hatipoglu N; Ozcelik T; Morelle G; Zatz M; Ng LFP; Lye DC; Young BE; Leo Y-S; Dalgard CL; Lifton RP; Renia L; Meyts I; Jouanguy E; Hammarstrom L; Pan-Hammarstrom Q; Boisson B; Bastard P; Su HC; Boisson-Dupuis S; Abel L; Rice CM; Zhang S-Y; Cobat A; Casanova J-L
• Article: ALLERGY. 2022;77(8):2415-2430

  Autoantibodies in COVID-19 correlate with antiviral humoral responses and distinct immune signatures

  Taeschler P; Cervia C; Zurbuchen Y; Hasler S; Pou C; Tan Z; Adamo S; Raeber ME; Bachli E; Rudiger A; Stussi-Helbling M; Huber LC; Brodin P; Nilsson J; Probst-Muller E; Boyman O
• Article: LANCET REGIONAL HEALTH-EUROPE. 2022;19:100443

  Risk factors for multisystem inflammatory syndrome in children - A population-based cohort study of over 2 million children

  Rhedin S; Lundholm C; Horne A; Smew AI; Osvald EC; Haddadi A; Alfven T; Kahn R; Krol P; Brew BH; Almqvist C
• Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2022;219(7):e20220202

  Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency

  Campbell TM; Liu Z; Zhang Q; Moncada-Velez M; Covill LE; Zhang P; Darazam IA; Bastard P; Bizien L; Bucciol G; Enoksson SL; Jouanguy E; Karabela SN; Khan T; Kendir-Demirkol Y; Augusto Arias A; Mansouri D; Marits P; Marr N; Migeotte I; Moens L; Ozcelik T; Pellier I; Sendel A; Senoglu S; Shahrooei M; Smith CIE; Vandernoot I; Willekens K; Yasar KK; Bergman P; Abel L; Cobat A; Casanova J-L; Meyts I; Bryceson YT
• Article: PHYSIOLOGICAL REPORTS. 2022;10(14):e15398

  MRI characterization of skeletal muscle size and fatty infiltration in long--term trained and untrained individuals

  Emanuelsson EB; Berry DB; Reitzner SM; Arif M; Mardinoglu A; Gustafsson T; Ward SR; Sundberg CJ; Chapman MA
• Letter: LANCET GASTROENTEROLOGY & HEPATOLOGY. 2022;7(7):594-595

  Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens

  Brodin P; Arditi M
• Article: ACTA PAEDIATRICA. 2022;111(7):1331-1337

  Validation of central nervous system-induced seizures and other neurological variables in the Swedish Neonatal Quality Register

  Westergren H; Hesla HM; Altman M; Wickstrom R
• Article: CELL REPORTS. 2022;39(13):110989

  Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation

  Posseme C; Llibre A; Charbit B; Bondet V; Rouilly V; Saint-Andre V; Boussier J; Bergstedt J; Smith N; Townsend L; Sugrue JA; Cheallaigh CN; Conlon N; Rotival M; Kobor MS; Mottez E; Pol S; Patin E; Albert ML; Quintana-Murci L; Duffy D
• Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2022;40(16_suppl):3107

  First-in-human (FIH) phase I study of the highly selective phosphoinositide 3-kinase inhibitor delta (PI3Kδ) inhibitor IOA-244 in patients with advanced cancer: Safety, activity, pharmacokinetic (PK), and pharmacodynamic (PD) results.

  Di Giacomo AM; Santangelo F; Amato G; Simonetti E; Graham J; Lahn MMF; van der Veen LA; Johnson Z; Pickering CA; Durini M; Tan Z; Tadepally L; Brodin P; Occhipinti M; Simonelli M; Carlo-Stella C; Santoro A; Spiliopoulou P; Evans TRJ; Maio M
• Review: SCIENCE. 2022;376(6596):945-950

  Immune-microbe interactions early in life: A determinant of health and disease long term

  Brodin P
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(21):e2200413119

  The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

  Manry J; Bastard P; Gervais A; Le Voyer T; Rosain J; Philippot Q; Michailidis E; Hoffmann H-H; Eto S; Garcia-Prat M; Bizien L; Parra-Martinez A; Yang R; Haljasmagi L; Migaud M; Sarekannu K; Maslovskaja J; de Prost N; Tandjaoui-Lambiotte Y; Luyt C-E; Amador-Borrero B; Gaudet A; Poissy J; Morel P; Richard P; Cognasse F; Troya J; Trouillet-Assant S; Belot A; Saker K; Garcon P; Riviere JG; Lagier J-C; Gentile S; Rosen LB; Shaw E; Morio T; Tanaka J; Dalmau D; Tharaux P-L; Sene D; Stepanian A; Megarbane B; Triantafyllia V; Fekkar A; Heath JR; Franco JL; Anaya J-M; Sole-Violan J; Imberti L; Biondi A; Bonfanti P; Castagnoli R; Delmonte OM; Zhang Y; Snow AL; Holland SM; Biggs CM; Moncada-Velez M; Arias AA; Lorenzo L; Boucherit S; Anglicheau D; Planas AM; Haerynck F; Duvlis S; Ozcelik T; Keles S; Bousfiha AA; El Bakkouri J; Ramirez-Santana C; Paul S; Pan-Hammarstrom Q; Hammarstrom L; Dupont A; Kurolap A; Metz CN; Aiuti A; Casari G; Lampasona V; Ciceri F; Barreiros LA; Dominguez-Garrido E; Vidigal M; Zatz M; van de Beek D; Sahanic S; Tancevski I; Stepanovskyy Y; Boyarchuk O; Nukui Y; Tsumura M; Vidaur L; Tangye SG; Burrel S; Duffy D; Quintana-Murci L; Klocperk A; Kann NY; Shcherbina A; Lau Y-L; Leung D; Coulongeat M; Marlet J; Koning R; Reyes LF; Chauvineau-Grenier A; Venet F; Monneret G; Nussenzweig MC; Arrestier R; Boudhabhay I; Baris-Feldman H; Hagin D; Wauters J; Meyts I; Dyer AH; Kennelly S; Bourkeh NM; Halwan R; Sharif-Askar FS; Dorgham K; Sallette J; Sedkaoui SM; AlKhater S; Rigo-Bonnin R; Morandeira F; Roussel L; Vinh DC; Erikstrup C; Condino-Neto A; Prando C; Bondarenko A; Spaan AN; Gilardin L; Fellay J; Lyonnet S; Bilguvar K; Lifton RP; Mane S; Anderson MS; Boisson B; Beziat V; Zhang S-Y; Andreakos E; Hermine O; Pujol A; Peterson P; Mogensen TH; Rowen L; Mond J; Debette S; de Lamballerie X; Burdet C; Bouadma L; Zins M; Soler-Palacin P; Colobran R; Gorochov G; Solanich X; Susen S; Martinez-Picado J; Raoult D; Vasse M; Gregersen PK; Piemonti L; Rodriguez-Gallego C; D Notarangelo L; Su HC; Kisand K; Okada S; Puel A; Jouanguy E; Rice CM; Tiberghien P; Zhang Q; Casanova J-L; Abel L; Cobat A
• Article: ALLERGY. 2022;77(5):1583-1595

  Longitudinal analyses of development of the immune system during the first five years of life in relation to lifestyle

  Olin A; Acevedo N; Lakshmikanth T; Chen Y; Johansson C; Alm J; Scheynius A; Brodin P
• Letter: NATURE MEDICINE. 2022;28(5):879-882

  Studying severe long COVID to understand post-infectious disorders beyond COVID-19

  Brodin P; Casari G; Townsend L; O'Farrelly C; Tancevski I; Loeffler-Ragg J; Mogensen TH; Casanova JL
• Review: CRITICAL CARE MEDICINE. 2022;50(5):860-872

  Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults

  Hines MR; Greenwood TVB; Beutel G; Beutel K; Hays JA; Horne A; Janka G; Jordan MB; van Laar JAM; Lachmann G; Lehmberg K; Machowicz R; Miettunen P; La Rosee P; Shakoory B; Zinter MS; Henter J-I
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: GLOBAL. 2022;1(2):37-42

  Lung function before and after COVID-19 in young adults: A population-based study.

  Mogensen I; Hallberg J; Björkander S; Du L; Zuo F; Hammarström L; Pan-Hammarström Q; Ekström S; Georgelis A; Palmberg L; Janson C; Bergström A; Melén E; Kull I; BAMSE COVID-19 Study Group
• Preprint: BIORXIV. 2022

  Data availability of open T-cell receptor repertoire data, a systematic assessment

  Huang Y-N; Patel NA; Mehta JH; Ginjala S; Brodin P; Gray C; Patel Y; Cowell L; Burkhardt A; Mangul S
• Article: GENES AND IMMUNITY. 2022;23(2):93-98

  Rhesus negative males have an enhanced IFNγ-mediated immune response to influenza A virus.

  Sugrue JA; Smith M; Posseme C; Charbit B; Milieu Interieur Consortium; Bourke NM; Duffy D; O'Farrelly C
• Article: CHILD PSYCHIATRY & HUMAN DEVELOPMENT. 2022;53(2):354-364

  A Two-to-Five Year Follow-Up of a Pediatric Acute-Onset Neuropsychiatric Syndrome Cohort

  Gromark C; Hesselmark E; Djupedal IG; Silverberg M; Horne A; Harris RA; Serlachius E; Mataix-Cols D
• Article: JAMA NETWORK OPEN. 2022;5(4):e228109

  Association of Short-term Air Pollution Exposure With SARS-CoV-2 Infection Among Young Adults in Sweden

  Yu Z; Bellander T; Bergstrom A; Dillner J; Eneroth K; Engardt M; Georgelis A; Kull I; Ljungman P; Pershagen G; Stafoggia M; Melen E; Gruzieva O
• Review: NATURE. 2022;603(7902):587-598

  Human genetic and immunological determinants of critical COVID-19 pneumonia

  Zhang Q; Bastard P; Cobat A; Casanova J-L
• Preprint: BIORXIV. 2022

  Graph deep learning reveals multiple signal pathways activated in anti-citrullinated protein antibodies stimulated synoviocytes

  Sun M; Chen Y; Brodin P; Catrina A
• Preprint: RESEARCH SQUARE. 2022

  Three adult cases of STAT1-gain-of-function with chronic mucocutaneous candidiasis treated with JAK inhibitors

  Borgström EW; Edvinsson M; Perez LP; Norlin A-C; Hansen S; Fasth A; Friman V; Kämpe O; Månsson R; Tan Z; Smith CIE; Brodin P; Bergman P
• Article: GENOME MEDICINE. 2022;14(1):28

  Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes.

  Caron B; Patin E; Rotival M; Charbit B; Albert ML; Quintana-Murci L; Duffy D; Rausell A; Milieu Intérieur Consortium
• Article: RHEUMATOLOGY. 2022;61(3):1228-1232

  Juvenile idiopathic arthritis, marriage and parenthood: a nationwide matched cohort study

  Bruze G; Askling J; Horne A; Neovius M
• Review: IMMUNITY. 2022;55(2):201-209

  SARS-CoV-2 infections in children: Understanding diverse outcomes

  Brodin P
• Corrigendum: NATURE IMMUNOLOGY. 2022;23(2):341

  A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection (Oct, 10.1038/s41590-021-01030-z, 2021)

  Andreakos E; Abel L; Vinh DC; Kaja E; Drolet BA; Zhang Q; O'Farrelly C; Novelli G; Rodriguez-Gallego C; Haerynck F; Prando C; Pujol A; Su HC; Casanova J-L; Spaan AN
• Article: NATURE IMMUNOLOGY. 2022;23(2):159-164

  A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection

  Andreakos E; Abel L; Vinh DC; Kaja E; Drolet BA; Zhang Q; O'Farrelly C; Novelli G; Rodriguez-Gallego C; Haerynck F; Prando C; Pujol A; Su HC; Casanova J-L; Spaan AN; Bastard P; Biggs CM; Bigio B; Boisson B; Bolze A; Bondarenko A; Brodin P; Chakravorty S; Christodoulou J; Cobat A; Condino-Neto A; Constantinescu SN; Feldman HB; Fellay J; Halwani R; Jouanguy E; Lau Y-L; Meyts I; Mogensen TH; Okada S; Okamoto K; Ozcelik T; Pan-Hammarstrom Q; Planas AM; Puel A; Quintana-Murci L; Renia L; Resnick I; Sediva A; Shcherbina A; Slaby O; Tancevski I; Turvey SE; Uddin KMF; van de Beek D; Zatz M; Zawadzki P; Zhang S-Y
• Article: ACTA PAEDIATRICA. 2022;111(2):354-362

  Population-based study of multisystem inflammatory syndrome associated with COVID-19 found that 36% of children had persistent symptoms

  Kahn R; Berg S; Berntson L; Berthold E; Brodin P; Backstrom F; Compagno M; Fasth A; Framme JL; Horne A; Hattting J; Krol P; Kukka AJ; Mossberg M; Mansson B; Nordenhall C; Nordstrom SI; Nystrom FK; Palmblad K; Rasti R; Rudolph A; Rydenman K; Sundberg E; Save-Soderbergh E; Altman M
• Preprint: MEDRXIV. 2022

  Autoantibodies in COVID-19 correlate with anti-viral humoral responses and distinct immune signatures

  Taeschler P; Cervia C; Zurbuchen Y; Hasler S; Pou C; Tan Z; Adamo S; Raeber ME; Bächli E; Rudiger A; Stüssi-Helbling M; Huber LC; Brodin P; Nilsson J; Probst-Müller E; Boyman O
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(1):65-75.e8

  SARS-CoV-2-specific B- and T-cell immunity in a population-based study of young Swedish adults

  Bjorkander S; Du L; Zuo F; Ekstrom S; Wang Y; Wan H; Sherina N; Schoutens L; Andrell J; Andersson N; Georgelis A; Bergstrom A; Marcotte H; Kull I; Hammarstrom L; Melen E; Pan-Hammarstrom Q
• Conference publication: CLINICAL CANCER RESEARCH. 2022;28(18)

  IGFBP5 is induced by tumor-suppressive naive stromal cells and regulates GAS2-associated apoptosis in rhabdomyosarcoma

  Ehnman M; Katkhada K; Meng LZ; Zhang Y; Zhao B; Tong S; Kallai A; Ostman A; Tobin N
• Journal article: FRONTIERS IN SYSTEMS BIOLOGY. 2022;2:918792

  Data Availability of Open T-Cell Receptor Repertoire Data, a Systematic Assessment

  Huang Y-N; Patel NA; Mehta JH; Ginjala S; Brodin P; Gray CM; Patel YM; Cowell LG; Burkhardt AM; Mangul S
• Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2022;40(16)

  First-in-human (FIH) phase I study of the highly selective phosphoinositide 3-kinase inhibitor delta (PI3Kδ) inhibitor IOA-244 in patients with advanced cancer: Safety, activity, pharmacokinetic (PK), and pharmacodynamic (PD) results.

  Di Giacomo AM; Santangelo F; Amato G; Simonetti E; Graham J; Lahn MMF; Van der Veen LA; Johnson Z; Pickering CA; Durini M; Tan Z; Tadepally L; Brodin P; Occhipinti M; Simonelli M; Carlo-Stella C; Santoro A; Spiliopoulou P; Evans TRJ; Maio M
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9):389

  MRI Characterization Of Skeletal Muscle Size And Fatty Infiltration In Long-term Trained And Untrained Individuals

  Emanuelsson EB; Berry D; Reitzner SM; Arif M; Mardinoglu A; Gustafsson T; Ward S; Sundberg CJ; Chapman MA
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9):628

  Metabolomic Response To Acute Endurance And Resistance Exercise In Life-long Trained Athletes And Untrained Individuals

  Reitzner SM; Arif M; Emanuelsson E; Chapman M; Mardinoglu A; Sundberg CJ
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9):392-393

  Skeletal Muscle Proteomics Comparison Between Long-term Trained And Untrained Men And Women

  Chapman M; Emanuelsson E; Arif M; Lakhia Z; Reitzner S; Mardinoglu A; Sundberg CJ
• Article: PEDIATRIC RHEUMATOLOGY. 2021;19(1):173

  Immunoprofiling of active and inactive systemic juvenile idiopathic arthritis reveals distinct biomarkers: a single-center study

  Qu H; Sundberg E; Aulin C; Neog M; Palmblad K; Horne AC; Granath F; Ek A; Melen E; Olsson M; Harris HE
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(12):2791-2796

  From Your Nose to Your Toes: A Review of Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic-Associated Pernio

  Arkin LM; Moon JJ; Tran JM; Asgan S; O'Farrelly C; Casanova J-L; Cowen EW; Mays JW; Singh AM; Drolet BA
• Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2021;32(8):1833-1842

  Virological and immunological features of SARS-COV-2 infected children with distinct symptomatology

  Cotugno N; Ruggiero A; Pascucci GR; Bonfante F; Petrara MR; Pighi C; Cifaldi L; Zangari P; Bernardi S; Cursi L; Santilli V; Manno EC; Amodio D; Linardos G; Piccioni L; Barbieri MA; Perrotta D; Campana A; Dona D; Giaquinto C; Concato C; Brodin P; Rossi P; De Rossi A; Palma P
• Article: JOURNAL OF RHEUMATOLOGY. 2021;48(10):1596-1602

  Efficacy of Moderately Dosed Etoposide in Macrophage Activation Syndrome-Hemophagocytic Lymphohistiocytosis

  Horne A; Greenwood TVB; Chiang SCC; Meeths M; Bjorklund C; Ekelund M; Erensjo P; Berg S; Hagelberg S; Bryceson YT; Andersson U; Henter J-I
• Article: SCIENCE IMMUNOLOGY. 2021;6(62):eabl4340

  Autoantibodies neutralizing type I IFNs are present in ∼4% of uninfected individuals over 70 years old and account for ∼20% of COVID-19 deaths

  Bastard P; Gervais A; Le Voyer T; Rosain J; Philippot Q; Manry J; Michailidis E; Hoffmann H-H; Eto S; Garcia-Prat M; Bizien L; Parra-Martinez A; Yang R; Haljasmagi L; Migaud M; Sarekannu K; Maslovskaja J; de Prost N; Tandjaoui-Lambiotte Y; Luyt C-E; Amador-Borrero B; Gaudet A; Poissy J; Morel P; Richard P; Cognasse F; Troya J; Trouillet-Assant S; Belot A; Saker K; Garcon P; Riviere JG; Lagier J-C; Gentile S; Rosen LB; Shaw E; Morio T; Tanaka J; Dalmau D; Tharaux P-L; Sene D; Stepanian A; Megarbane B; Triantafyllia V; Fekkar A; Heath JR; Franco JL; Anaya J-M; Sole-Violan J; Imberti L; Biondi A; Bonfanti P; Castagnoli R; Delmonte OM; Zhang Y; Snow AL; Holland SM; Biggs CM; Moncada-Velez M; Arias AA; Lorenzo L; Boucherit S; Coulibaly B; Anglicheau D; Planas AM; Haerynck F; Duvlis S; Nussbaum RL; Ozcelik T; Keles S; Bousfiha AA; El Bakkouri J; Ramirez-Santana C; Paul S; Pan-Hammarstrom Q; Hammarstrom L; Dupont A; Kurolap A; Metz CN; Aiuti A; Casari G; Lampasona V; Ciceri F; Barreiros LA; Dominguez-Garrido E; Vidigal M; Zatz M; van de Beek D; Sahanic S; Tancevski I; Stepanovskyy Y; Boyarchuk O; Nukui Y; Tsumura M; Vidaur L; Tangye SG; Burrel S; Duffy D; Quintana-Murci L; Klocperk A; Kann NY; Shcherbina A; Lau Y-L; Leung D; Coulongeat M; Marlet J; Koning R; Reyes LF; Chauvineau-Grenier A; Venet F; Monneret G; Nussenzweig MC; Arrestier R; Boudhabhay I; Baris-Feldman H; Hagin D; Wauters J; Meyts I; Dyer AH; Kennelly SP; Bourke NM; Halwani R; Sharif-Askari NS; Dorgham K; Sallette J; Sedkaoui SM; AlKhater S; Rigo-Bonnin R; Morandeira F; Roussel L; Vinh DC; Ostrowski SR; Condino-Neto A; Prando C; Bondarenko A; Spaan AN; Gilardin L; Fellay J; Lyonnet S; Bilguvar K; Lifton RP; Mane S; Anderson MS; Boisson B; Beziat V; Zhang S-Y; Andreakos E; Hermine O; Pujol A; Peterson P; Mogensen TH; Rowen L; Mond J; Debette S; de Lamballerie X; Duval X; Mentre F; Zins M; Soler-Palacin P; Colobran R; Gorochov G; Solanich X; Susen S; Martinez-Picado J; Raoult D; Vasse M; Gregersen PK; Piemonti L; Rodriguez-Gallego C; Notarangelo LD; Su HC; Kisand K; Okada S; Puel A; Jouanguy E; Rice CM; Tiberghien P; Zhang Q; Cobat A; Abel L; Casanova J-L
• Article: SCIENCE IMMUNOLOGY. 2021;6(62):eabl4348

  X-linked recessive TLR7 deficiency in ∼1% of men under 60 years old with life-threatening COVID-19

  Asano T; Boisson B; Onodi F; Matuozzo D; Moncada-Velez M; Renkilaraj MRLM; Zhang P; Meertens L; Bolze A; Materna M; Korniotis S; Gervais A; Talouarn E; Bigio B; Seeleuthner Y; Bilguvar K; Zhang Y; Neehus A-L; Ogishi M; Pelham SJ; Le Voyer T; Rosain J; Philippot Q; Soler-Palacin P; Colobran R; Martin-Nalda A; Riviere JG; Tandjaoui-Lambiotte Y; Chaibi K; Shahrooei M; Darazam IA; Olyaei NA; Mansouri D; Palabiyik F; Ozcelik T; Novelli G; Novelli A; Casari G; Aiuti A; Carrera P; Bondesan S; Barzaghi F; Rovere-Querini P; Tresoldi C; Franco JL; Rojas J; Reyes LF; Bustos IG; Arias AA; Morelle G; Kyheng C; Troya J; Planas-Serra L; Schluter A; Gut M; Pujol A; Allende LM; Rodriguez-Gallego C; Flores C; Cabrera-Marante O; Pleguezuelo DE; de Diego RP; Keles S; Aytekin G; Akcan OM; Bryceson YT; Bergman P; Brodin P; Smole D; Smith CIE; Norlin A-C; Campbell TM; Covill LE; Hammarstrom L; Pan-Hammarstrom Q; Abolhassani H; Mane S; Marr N; Ata M; Al Ali F; Khan T; Spaan AN; Dalgard CL; Bonfanti P; Biondi A; Tubiana S; Burdet C; Nussbaum R; Kahn-Kirby A; Snow AL; Bustamante J; Puel A; Boisson-Dupuis S; Zhang S-Y; Beziat V; Lifton RP; Bastard P; Notarangelo LD; Abel L; Su HC; Jouanguy E; Amara A; Soumelis V; Cobat A; Zhang Q; Casanova J-L
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;148(2):407-419

  Lung function fluctuation patterns unveil asthma and COPD phenotypes unrelated to type 2 inflammation

  Delgado-Eckert E; James A; Meier-Girard D; Kupczyk M; Andersson LI; Bossios A; Mikus M; Ono J; Izuhara K; Middelveld R; Dahlen B; Gaga M; Siafakas NM; Papi A; Beghe B; Joos G; Rabe KF; Sterk PJ; Bel EH; Johnston SL; Chanez P; Gjomarkaj M; Howarth PH; Nizankowska-Mogilnicka E; Dahlen S-E; Frey U
• Article: LANCET RHEUMATOLOGY. 2021;3(8):E563-E573

  Definition and validation of serum biomarkers for optimal differentiation of hyperferritinaemic cytokine storm conditions in children: a retrospective cohort study

  Kessel C; Fall N; Grom A; de Jager W; Vastert S; Strippoli R; Bracaglia C; Sundberg E; Horne A; Ehl S; Ammann S; Wouters C; Lehmberg K; De Benedetti F; Park C; Hinze C; Wittkowski H; Kessel K; Beutel K; Foell D; Holzinger D
• Article: JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. 2021;40(1):240

  A vision of immuno-oncology: the Siena think tank of the Italian network for tumor biotherapy (NIBIT) foundation

  Maio M; Lahn M; Di Giacomo AM; Covre A; Calabro L; Ibrahim R; Fox B
• Article: CELL. 2021;184(15):3884-3898.e11

  Bifidobacteria-mediated immune system imprinting early in life

  Henrick BM; Rodriguez L; Lakshmikanth T; Pou C; Henckel E; Arzoomand A; Olin A; Wang J; Mikes J; Tan Z; Chen Y; Ehrlich AM; Bernhardsson AK; Mugabo CH; Ambrosiani Y; Gustafsson A; Chew S; Brown HK; Prambs J; Bohlin K; Mitchell RD; Underwood MA; Smilowitz JT; German JB; Frese SA; Brodin P
• Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;148(1):96-98

  Severe COVID-19 in an APS1 patient with interferon autoantibodies treated with plasmapheresis

  Lemarquis A; Campbell T; Aranda-Guillen M; Hennings V; Brodin P; Kampe O; Blennow K; Zetterberg H; Wenneras C; Eriksson K; Landegren N; Bryceson Y; Berg S; Ekwall O
• Article: NEW ENGLAND JOURNAL OF MEDICINE. 2021;385(1):11-22

  Treatment of Multisystem Inflammatory Syndrome in Children

  McArdle AJ; Vito O; Patel H; Seaby EG; Shah P; Wilson C; Broderick C; Nijman R; Tremoulet AH; Munblit D; Ulloa-Gutierrez R; Carter MJ; De T; Hoggart C; Whittaker E; Herberg JA; Kaforou M; Cunnington AJ; Levin M
• Review: JOURNAL OF EXPERIMENTAL MEDICINE. 2021;218(6):e20210446

  SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?

  Sancho-Shimizu V; Brodin P; Cobat A; Biggs CM; Toubiana J; Lucas CL; Henrickson SE; Belot A; Tangye SG; Milner JD; Levin M; Abel L; Bogunovic D; Casanova J-L; Zhang S-Y
• Editorial comment: NATURE METHODS. 2021;18(6):588-591

  Diversity in immunogenomics: the value and the challenge

  Peng K; Safonova Y; Shugay M; Popejoy AB; Rodriguez OL; Breden F; Brodin P; Burkhardt AM; Bustamante C; Cao-Lormeau V-M; Corcoran MM; Duffy D; Fuentes-Guajardo M; Fujita R; Greiff V; Jonsson VD; Liu X; Quintana-Murci L; Rossetti M; Xie J; Yaari G; Zhang W; Abedalthagafi MS; Adekoya KO; Ahmed RA; Chang W-C; Gray C; Nakamura Y; Lees WD; Khatri P; Alachkar H; Scheepers C; Watson CT; Karlsson Hedestam GB; Mangul S
• Article: JOURNAL OF PEDIATRICS. 2021;233:43-50.e5

  Neonatal Morbidities in Infants Born Late Preterm at 35-36 Weeks of Gestation: A Swedish Nationwide Population-based Study

  Mitha A; Chen R; Altman M; Johansson S; Stephansson O; Bolk J
• Article: LAKARTIDNINGEN. 2021;118:21136

  Viktigt att uppmärksamma MIS-A inom vuxensjukvården.

  Brodin P
• Article: MOLECULAR MEDICINE. 2021;27(1):48

  Therapeutic administration of etoposide coincides with reduced systemic HMGB1 levels in macrophage activation syndrome

  Palmblad K; Schierbeck H; Sundberg E; Horne A-C; Harris HE; Henter J-I; Andersson U
• Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2021;72(5):e119-e124

  Long-term Follow-up for Missed Cases of Eosinophilic Esophagitis in Children With Previous Foreign Body in the Esophagus

  Thulin H; Nilsson C; Svensson JF; Olen O; Altman M
• Preprint: BIORXIV. 2021

  Stimulation with mycobacterial glycolipids and PPD reveals different innate immune response profiles in active and latent TB

  Silva C; Sundling C; Folkeson E; Fröberg G; Nobrega C; Canto-Gomes J; Chambers B; Lakshmikanth T; Brodin P; Bruchfeld J; Nigou J; Correia-Neves M; Källenius G
• Article: PSYCHONEUROENDOCRINOLOGY. 2021;126:105162

  Autoantibodies against the C-terminus of Lipopolysaccharide binding protein are elevated in young adults with psychiatric disease

  Just D; Rasmusson AJ; Nilsson P; Noreland M; Malmstrom E; Brodin P; Manberg A; Cunningham JL
• Article: ERJ OPEN RESEARCH. 2021;7(2):917-2020

  Nasal upregulation of CST1 in dog-sensitised children with severe allergic airway disease

  Kack U; Einarsdottir E; van Hage M; Asarnoj A; James A; Nopp A; Krjutskov K; Katayama S; Kere J; Lilja G; Soderhall C; Konradsen JR
• Article: CELL REPORTS. 2021;34(11):108852

  Virological and immunological features of SARS-CoV-2-infected children who develop neutralizing antibodies

  Cotugno N; Ruggiero A; Bonfante F; Petrara MR; Zicari S; Pascucci GR; Zangari P; De Ioris MA; Santilli V; Manno EC; Amodio D; Bortolami A; Pagliari M; Concato C; Linardos G; Campana A; Dona D; Giaquinto C; Brodin P; Rossi P; De Rossi A; Palma P
• Journal article: PEDIATRICS. 2021;147(3_MeetingAbstract):684-685

  B. infantis EVC001 Colonization in Breastfed Infants Modulates Cytokine Profile Linked to Autoimmune and Allergic Diseases

  Henrick BM; Chew S; Prambs J; Brown HK; Underwood M; Smilowitz JT; Brodin P; German B
• Editorial comment: ACTA PAEDIATRICA. 2021;110(2):641-642

  YKL-40 is a proposed biomarker of inflammation and remodelling elevated in children with bronchopulmonary dysplasia compared to asthma

  James AJ; Nordlund B; Konradsen JR; Ebersjo C; Dahlen S-E; Berggren Brostrom E; Hedlin G
• Article: PEDIATRIC RESEARCH. 2021;89(3):604-612

  Dramatic changes in blood protein levels during the first week of life in extremely preterm infants

  Zhong W; Danielsson H; Tebani A; Karlsson MJ; Elfvin A; Hellgren G; Brusselaers N; Brodin P; Hellstrom A; Fagerberg L; Uhlen M
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2021;80(2):194-202

  Natural killer cells and type II interferon in Ro/SSA and La/SSB autoantibody-exposed newborns at risk of congenital heart block

  Ivanchenko M; Thorlacius GE; Hedlund M; Ottosson V; Meneghel L; Bjorkander S; Ossoinak A; Tingstrom J; Bremme K; Sverremark-Ekstrom E; Gemzell-Danielsson K; Sonesson S-E; Chemin K; Wahren-Herlenius M
• Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2021;51(2):262-272

  Multimorbidity in asthma, association with allergy, inflammatory markers and symptom burden, results from the Swedish GA²LEN study

  Blondal V; Malinovschi A; Sundbom F; James A; Middelveld R; Franklin KA; Lundback B; Janson C
• Article: CHILDREN-BASEL. 2021;8(2):80

  A Novel Association between YKL-40, a Marker of Structural Lung Disease, and Short Telomere Length in 10-Year-Old Children with Bronchopulmonary Dysplasia

  Henckel E; James A; Konradsen JR; Nordlund B; Kjellberg M; Berggren-Brostrom E; Hedlin G; Degerman S; Bohlin K
• Article: IMMUNITY & AGEING. 2021;18(1):5

  Aging and CMV discordance are associated with increased immune diversity between monozygotic twins

  Yan Z; Maecker HT; Brodin P; Nygaard UC; Lyu SC; Davis MM; Nadeau KC; Andorf S
• Article: FRONTIERS IN IMMUNOLOGY. 2021;12:727300

  High Dimensional Immune Profiling Reveals Different Response Patterns in Active and Latent Tuberculosis Following Stimulation With Mycobacterial Glycolipids

  Silva CS; Sundling C; Folkesson E; Froberg G; Nobrega C; Canto-Gomes J; Chambers BJ; Lakshmikanth T; Brodin P; Bruchfeld J; Nigou J; Correia-Neves M; Kallenius G
• Article: NATURE MEDICINE. 2021;27(1):28-33

  Immune determinants of COVID-19 disease presentation and severity

  Brodin P
• Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2021;203(1):37-53

  Urinary Leukotriene E₄ and Prostaglandin D₂ Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation A Clinical Observational Study

  Kolmert J; Gomez C; Balgoma D; Sjodin M; Bood J; Konradsen JR; Ericsson M; Thorngren J-O; James A; Mikus M; Sousa AR; Riley JH; Bates S; Bakke PS; Pandis I; Caruso M; Chanez P; Fowler SJ; Geiser T; Howarth P; Horvath I; Krug N; Montuschi P; Sanak M; Behndig A; Shaw DE; Knowles RG; Holweg CTJ; Wheelock AM; Dahlen B; Nordlund B; Alving K; Hedlin G; Chung KF; Adcock IM; Sterk PJ; Djukanovic R; Dahlen S-E; Wheelock CE
• Other: MOLECULAR MEDICINE. 2020;26(1):131

  High systemic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome (Retraction of Vol 20, Pg 538, 2014)

  Palmblad K; Schierbeck H; Sundberg E; Horne A-C; Harris HE; Henter J-I; Antoine DJ; Andersson U
• Article: MED. 2020;1(1):14-20

  Life-Threatening COVID-19: Defective Interferons Unleash Excessive Inflammation.

  Zhang Q; Bastard P; Bolze A; Jouanguy E; Zhang S-Y; COVID Human Genetic Effort; Cobat A; Notarangelo LD; Su HC; Abel L; Casanova J-L
• Article: SCIENTIFIC REPORTS. 2020;10(1):20425

  High CD45 expression of CD8+and CD4+T cells correlates with the size of HIV-1 reservoir in blood

  Petkov S; Bekele Y; Lakshmikanth T; Hejdeman B; Zazzi M; Brodin P; Chiodi F
• Article: CELL. 2020;183(4):968-981.e7

  The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19

  Consiglio CR; Cotugno N; Sardh F; Pou C; Amodio D; Rodriguez L; Tan Z; Zicari S; Ruggiero A; Pascucci GR; Santilli V; Campbell T; Bryceson Y; Eriksson D; Wang J; Marchesi A; Lakshmikanth T; Campana A; Villani A; Rossi P; Landegren N; Palma P; Brodin P
• Preprint: BIORXIV. 2020

  Bifidobacteria-mediated immune system imprinting early in life

  Henrick B; Rodriguez L; Lakshmikanth T; Pou C; Henckel E; Olin A; Wang J; Mikes J; Tan Z; Chen Y; Ehrlich A; Bernhardsson AK; Mugabo CH; Ambrosiani Y; Gustafsson A; Chew S; Brown H; Prambs J; Bohlin K; Mitchell R; Underwood M; Smilowitz J; German B; Frese S; Brodin P
• Article: ELIFE. 2020;9:e59996

  Cytotoxic T-cells mediate exercise-induced reductions in tumor growth

  Rundqvist H; Velica P; Barbieri L; Gameiro PA; Bargiela D; Gojkovic M; Mijwel S; Reitzner SM; Wulliman D; Ahlstedt E; Ule J; Ostman A; Johnson RS
• Article: SCIENCE. 2020;370(6515):eabd4585

  Autoantibodies against type I IFNs in patients with life-threatening COVID-19

  Bastard P; Rosen LB; Zhang Q; Michailidis E; Hoffmann H-H; Zhang Y; Dorgham K; Philippot Q; Rosain J; Beziat V; Manry J; Shaw E; Haljasmagi L; Peterson P; Lorenzo L; Bizien L; Trouillet-Assant S; Dobbs K; de Jesus AA; Belot A; Kallaste A; Catherinot E; Tandjaoui-Lambiotte Y; Le Pen J; Kerner G; Bigio B; Seeleuthner Y; Yang R; Bolze A; Spaan AN; Delmonte OM; Abers MS; Aiuti A; Casari G; Lampasona V; Piemonti L; Ciceri F; Bilguvar K; Lifton RP; Vasse M; Smadja DM; Migaud M; Hadjadj J; Terrier B; Duffy D; Quintana-Murci L; van de Beek D; Roussel L; Vinh DC; Tangye SG; Haerynck F; Dalmau D; Martinez-Picado J; Brodin P; Nussenzweig MC; Boisson-Dupuis S; Rodriguez-Gallego C; Vogt G; Mogensen TH; Oler AJ; Gu J; Burbelo PD; Cohen JI; Biondi A; Bettini LR; D'Angio M; Bonfanti P; Rossignol P; Mayaux J; Rieux-Laucat F; Husebye ES; Fusco F; Ursini MV; Imberti L; Sottini A; Paghera S; Quiros-Roldan E; Rossi C; Castagnoli R; Montagna D; Licari A; Marseglia GL; Duval X; Ghosn J; Tsang JS; Goldbach-Mansky R; Kisand K; Lionakis MS; Puel A; Zhang S-Y; Holland SM; Gorochov G; Jouanguy E; Rice CM; Cobat A; Notarangelo LD; Abel L; Su HC; Casanova J-L
• Article: SCIENCE. 2020;370(6515):eabd4570

  Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

  Zhang Q; Bastard P; Liu Z; Le Pen J; Moncada-Velez M; Chen J; Ogishi M; Sabli IKD; Hodeib S; Korol C; Rosain J; Bilguvar K; Ye J; Bolze A; Bigio B; Yang R; Arias AA; Zhou Q; Zhang Y; Onodi F; Korniotis S; Karpf L; Philippot Q; Chbihi M; Bonnet-Madin L; Dorgham K; Smith N; Schneider WM; Razooky BS; Hoffmann H-H; Michailidis E; Moens L; Han JE; Lorenzo L; Bizien L; Meade P; Neehus A-L; Ugurbil AC; Corneau A; Kerner G; Zhang P; Rapaport F; Seeleuthner Y; Manry J; Masson C; Schmitt Y; Schlueter A; Le Voyer T; Khan T; Li J; Fellay J; Roussel L; Shahrooei M; Alosaimi MF; Mansouri D; Al-Saud H; Al-Mulla F; Almourfi F; Al-Muhsen SZ; Alsohime F; Al Turki S; Hasanato R; van de Beek D; Biondi A; Bettini LR; D'Angio M; Bonfanti P; Imberti L; Sottini A; Paghera S; Quiros-Roldan E; Rossi C; Oler AJ; Tompkins MF; Alba C; Vandernoot I; Goffard J-C; Smits G; Migeotte I; Haerynck F; Soler-Palacin P; Martin-Nalda A; Colobran R; Morange P-E; Keles S; Colkesen F; Ozcelik T; Yasar KK; Senoglu S; Karabela SN; Rodriguez-Gallego C; Novelli G; Hraiech S; Tandjaoui-Lambiotte Y; Duval X; Laouenan C; Snow AL; Dalgard CL; Milner JD; Vinh DC; Mogensen TH; Marr N; Spaan AN; Boisson B; Boisson-Dupuis S; Bustamante J; Puel A; Ciancanelli MJ; Meyts I; Maniatis T; Soumelis V; Amara A; Nussenzweig M; Garcia-Sastre A; Krammer F; Pujol A; Duffy D; Lifton RP; Zhang S-Y; Gorochov G; Beziat V; Jouanguy E; Sancho-Shimizu V; Rice CM; Abel L; Notarangelo LD; Cobat A; Su HC; Casanova J-L
• Editorial comment: JOURNAL OF CLINICAL IMMUNOLOGY. 2020;40(7):958-959

  Unraveling the Immune Response in Severe COVID-19

  Rodriguez L; Brodin P
• Article: NATURE COMMUNICATIONS. 2020;11(1):4487

  Integration of molecular profiles in a longitudinal wellness profiling cohort

  Tebani A; Gummesson A; Zhong W; Koistinen IS; Lakshmikanth T; Olsson LM; Boulund F; Neiman M; Stenlund H; Hellstrom C; Karlsson MJ; Arif M; Dodig-Crnkovic T; Mardinoglu A; Lee S; Zhang C; Chen Y; Olin A; Mikes J; Danielsson H; von Feilitzen K; Jansson P-A; Angeras O; Huss M; Kjellqvist S; Odeberg J; Edfors F; Tremaroli V; Forsstrom B; Schwenk JM; Nilsson P; Moritz T; Backhed F; Engstrand L; Brodin P; Bergstrom G; Uhlen M; Fagerberg L
• Article: CELL REPORTS MEDICINE. 2020;1(5):100078

  Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19

  Rodriguez L; Pekkarinen PT; Lakshmikanth T; Tan Z; Consiglio CR; Pou C; Chen Y; Mugabo CH; Nguyen NA; Nowlan K; Strandin T; Levanov L; Mikes J; Wang J; Kantele A; Hepojoki J; Vapalahti O; Heinonen S; Kekalainen E; Brodin P
• Doctoral thesis: 2020

  Exercise-induced molecular mechanisms in untrained and life-long highly trained individuals

  Reitzner, Stefan Markus
• Article: BLOOD ADVANCES. 2020;4(15):3754-3766

  Stem cell transplantation for children with hemophagocytic lymphohistiocytosis: results from the HLH-2004 study

  Bergsten E; Horne A; Myrberg IH; Arico M; Astigarraga I; Ishii E; Janka G; Ladisch S; Lehmberg K; McClain KL; Minkov M; Nanduri V; Rosso DA; Sieni E; Winiarski J; Henter J-I
• Editorial comment: CURRENT OPINION IN IMMUNOLOGY. 2020;65:iv

  Editorial overview: Evolutionary and systems immunology - methods to understand human immune system variation.

  Brodin P; Quintana-Murci L
• Article: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2020;52(8):1679-1690

  Exercise Induces Different Molecular Responses in Trained and Untrained Human Muscle

  Moberg M; Lindholm ME; Reitzner SM; Ekblom B; Sundberg C-J; Psilander N
• Review: CURRENT OPINION IN IMMUNOLOGY. 2020;65:28-31

  Technologies for assessing vaccine responses in the very young

  Brodin P
• Preprint: BIORXIV. 2020

  Single-cell classification using learned cell phenotypes

  Chen Y; Lakshmikanth T; Mikes J; Brodin P
• Article: CELL REPORTS. 2020;32(3):107923

  Human Immune System Variation during 1 Year

  Lakshmikanth T; Muhammad SA; Olin A; Chen Y; Mikes J; Fagerberg L; Gummesson A; Bergstrom G; Uhlen M; Brodin P
• Article: RHEUMATOLOGY. 2020;59(7):1651-1661

  Viral antigens elicit augmented immune responses in primary Sjogren's syndrome

  Bjork A; Thorlacius GE; Mofors J; Andersson ER; Ivanchenko M; Tingstrom J; James T; Brokstad KA; Cox RJ; Jonsson R; Kvarnstrom M; Wahren-Herlenius M
• Article: ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION. 2020;105(4):F375-F379

  Diagnostic values of the femoral pulse palpation test

  Nystrom FK; Petersson G; Stephansson O; Johansson S; Altman M
• Article: CELL REPORTS. 2020;31(12):107808

  Skeletal Muscle Transcriptomic Comparison between Long-Term Trained and Untrained Men and Women

  Chapman MA; Arif M; Emanuelsson EB; Reitzner SM; Lindholm ME; Mardinoglu A; Sundberg CJ
• Editorial comment: CELL. 2020;181(6):1194-1199

  A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection.

  Casanova J-L; Su HC; COVID Human Genetic Effort
• Article: LAKARTIDNINGEN. 2020;117:20094

  [Severe inflammation in children - cause for awareness during the current pandemic].

  Horne A; Nordenhäll L
• Editorial comment: ACTA PAEDIATRICA. 2020;109(6):1082-1083

  Why is COVID-19 so mild in children?

  Brodin P
• Review: HUMAN GENETICS. 2020;139(6-7):795-799

  New approaches to the study of immune responses in humans

  Brodin P
• Article: PEDIATRIC BLOOD & CANCER. 2020;67(4):e28184

  Diagnostic challenges for a novel SH2D1A mutation associated with X-linked lymphoproliferative disease

  Torralba-Raga L; Tesi B; Chiang SCC; Schlums H; Nordenskjoeld M; Horne A; Henter J-I; Meeths M; Abdelhaleem M; Weitzman S; Bryceson Y
• Editorial comment: CELL. 2020;180(5):820-821

  Stressful Beginnings with Long-Term Consequences

  Consiglio CR; Brodin P
• Article: GENOME MEDICINE. 2020;12(1):25

  Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.

  Merid SK; Novoloaca A; Sharp GC; Küpers LK; Kho AT; Roy R; Gao L; Annesi-Maesano I; Jain P; Plusquin M; Kogevinas M; Allard C; Vehmeijer FO; Kazmi N; Salas LA; Rezwan FI; Zhang H; Sebert S; Czamara D; Rifas-Shiman SL; Melton PE; Lawlor DA; Pershagen G; Breton CV; Huen K; Baiz N; Gagliardi L; Nawrot TS; Corpeleijn E; Perron P; Duijts L; Nohr EA; Bustamante M; Ewart SL; Karmaus W; Zhao S; Page CM; Herceg Z; Jarvelin M-R; Lahti J; Baccarelli AA; Anderson D; Kachroo P; Relton CL; Bergström A; Eskenazi B; Soomro MH; Vineis P; Snieder H; Bouchard L; Jaddoe VW; Sørensen TIA; Vrijheid M; Arshad SH; Holloway JW; Håberg SE; Magnus P; Dwyer T; Binder EB; DeMeo DL; Vonk JM; Newnham J; Tantisira KG; Kull I; Wiemels JL; Heude B; Sunyer J; Nystad W; Munthe-Kaas MC; Räikkönen K; Oken E; Huang R-C; Weiss ST; Antó JM; Bousquet J; Kumar A; Söderhäll C; Almqvist C; Cardenas A; Gruzieva O; Xu C-J; Reese SE; Kere J; Brodin P; Solomon O; Wielscher M; Holland N; Ghantous A; Hivert M-F; Felix JF; Koppelman GH; London SJ; Melén E
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;145(3):808-817.e2

  IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways

  Manson ML; Safholm J; James A; Johnsson A-K; Bergman P; Al-Ameri M; Orre A-C; Karrman-Mardh C; Dahlen S-E; Adner M
• Other: MOLECULAR MEDICINE. 2020;26(1):17

  High systematic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome (Expression of Concern of Vol 20, Pg 538, 2014)

  Palmblad K; Schierbeck H; Sundberg E; Horne A-C; Harris HE; Henter J-I; Antoine DJ; Andersson U
• Review: CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. 2020;20(1):71-79

  Systemic and breath biomarkers for asthma: an update

  Mogensen I; James A; Malinovschi A
• Article: RMD OPEN. 2020;6(1):e000989

  Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero

  Hedlund M; Thorlacius GE; Ivanchenko M; Ottosson V; Kyriakidis N; Lagnefeldt L; Tingstrom J; Sirsjo A; Bengtsson AA; Aronsson E; Gemzell-Danielsson K; Ronnblom L; Bergman G; Espinosa A; Sonesson S-E; Eloranta M-L; Wahren-Herlenius M
• Article: SCIENCE. 2019;366(6472):eaax9198

  A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

  Uhlen M; Karlsson MJ; Zhong W; Tebani A; Pou C; Mikes J; Lakshmikanth T; Forsstrom B; Edfors F; Odeberg J; Mardinoglu A; Zhang C; von Feilitzen K; Mulder J; Sjostedt E; Hober A; Oksvold P; Zwahlen M; Ponten F; Lindskog C; Sivertsson A; Fagerberg L; Brodin P
• Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2019;216(12):2778-2799

  A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

  Lam MT; Coppola S; Krumbach OHF; Prencipe G; Insalaco A; Cifaldi C; Brigida I; Zara E; Scala S; Di Cesare S; Martinelli S; Di Rocco M; Pascarella A; Niceta M; Pantaleoni F; Ciolfi A; Netter P; Carisey AF; Diehl M; Akbarzadeh M; Conti F; Merli P; Pastore A; Mortera SL; Camerini S; Farina L; Buchholzer M; Pannone L; Cao TN; Coban-Akdemir ZH; Jhangiani SN; Muzny DM; Gibbs RA; Basso-Ricci L; Chiriaco M; Dvorsky R; Putignani L; Carsetti R; Janning P; Stray-Pedersen A; Erichsen HC; Horne A; Bryceson YT; Torralba-Raga L; Ramme K; Rosti V; Bracaglia C; Messia V; Palma P; Finocchi A; Locatelli F; Chinn IK; Lupski JR; Mace EM; Cancrini C; Aiuti A; Ahmadian MR; Orange JS; De Benedetti F; Tartaglia M
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(12):1621-1631

  Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts

  Sun M; Rethi B; Krishnamurthy A; Joshua V; Circiumaru A; Hensvold AH; Ossipova E; Gronwall C; Liu Y; Engstrom M; Catrina SB; Steen J; Malmstrom V; Klareskog L; Svensson C; Ospelt C; Wahamaa H; Catrina AI
• Review: JAMA PEDIATRICS. 2019;173(11):1032-1040

  Association of Use of the Neonatal Early-Onset Sepsis Calculator With Reduction in Antibiotic Therapy and Safety A Systematic Review and Meta-analysis

  Achten NB; Klingenberg C; Benitz WE; Stocker M; Schlapbach LJ; Giannoni E; Bokelaar R; Driessen GJA; Brodin P; Uthaya S; van Rossum AMC; Plotz FB
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(5):1198-1213

  IL-17-high asthma with features of a psoriasis immunophenotype

  Oestling J; van Geest M; Schofield JPR; Jevnikar Z; Wilson S; Ward J; Lutter R; Shaw DE; Bakke PS; Caruso M; Dahlen S-E; Fowler SJ; Horvath I; Krug N; Montuschi P; Sanak M; Sandstrom T; Sun K; Pandis I; Auffray C; Sousa AR; Guo Y; Adcock IM; Howarth P; Chung KF; Bigler J; Sterk PJ; Skipp PJ; Djukanovic R; Vaarala O; Ahmed H; Auffray C; Bakke P; Bansal AT; Baribaud F; Bates S; Bel EH; Bigler J; Bisgaard H; Boedigheimer MJ; Bonnelykke K; Brandsma J; Brinkman P; Bucchioni E; Burg D; Bush A; Caruso M; Chaiboonchoe A; Chanez P; Chung KF; Compton CH; Corfield J; D'Amico A; Dahlen SE; De Meulder B; Djukanovic R; Erpenbeck VJ; Erzen D; Fichtner K; Fitch N; Fleming LJ; Formaggio E; Fowler SJ; Frey U; Gahlemann M; Geiser T; Guo Y; Hashimoto S; Haughney J; Hedlin G; Hekking PW; Higenbottam T; Hohlfeld JM; Holweg C; Horvath I; Howarth P; James AJ; Knowles R; Knox AJ; Krug N; Lefaudeux D; Loza MJ; Lutter R; Manta A; Masefield S; Matthews JG; Mazein A; Meiser A; Middelveld RJM; Miralpeix M; Montuschi P; Mores N; Murray CS; Musial J; Myles D; Pahus L; Pandis I; Pavlidis S; Powell P; Pratico G; Valls MP; Rao N; Riley J; Roberts A; Roberts G; Rowe A; Sandstrom T; Seibold W; Selby A; Shaw DE; Sigmund R; Singer F; Skipp PJ; Sousa AR; Sterk PJ; Sun K; Thornton B; van Aalderen WM; van Geest M; Vestbo J; Vissing NH; Wagener AH; Wagers SS; Weiszhart Z; Wheelock CE; Wilson SJ
• Review: LAKARTIDNINGEN. 2019;116:FSR7

  [Born a few weeks too early; does it matter?].

  Bonnevier A; Björklund L; Elfvin A; Håkansson S; Altman M
• Article: JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY. 2019;29(8):625-633

  Establishing a Pediatric Acute-Onset Neuropsychiatric Syndrome Clinic: Baseline Clinical Features of the Pediatric Acute-Onset Neuropsychiatric Syndrome Cohort at Karolinska Institutet

  Gromark C; Harris RA; Wickstrom R; Horne A; Silverberg-Morse M; Serlachius E; Mataix-Cols D
• Article: PLOS BIOLOGY. 2019;17(10):e3000383

  Cell generation dynamics underlying naive T-cell homeostasis in adult humans

  Mold JE; Reu P; Olin A; Bernard S; Michaelsson J; Rane S; Yates A; Khosravi A; Salehpour M; Possnert G; Brodin P; Frisen J
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(10):1357-1362

  Development and initial validation of the MS score for diagnosis of macrophage activation syndrome in systemic juvenile idiopathic arthritis

  Minoia F; Bovis F; Davi S; Horne A; Fischbach M; Frosch M; Huber A; Jelusic M; Sawhney S; McCurdy DK; Silva CA; Rigante D; Unsal E; Ruperto N; Martini A; Cron RQ; Ravelli A
• Editorial comment: ACTA PAEDIATRICA. 2019;108(7):1357-1358

  Leucocytosis is associated with retinopathy of prematurity in extremely preterm infants

  Lundgren P; Klevebro S; Brodin P; Smith LEH; Hallberg B; Hellstrom A
• Editorial comment: NATURE MEDICINE. 2019;25(7):1026

  Seeking the ultimate challenge

  Brodin P
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(1):70-82

  Stratification of asthma phenotypes by airway proteomic signatures

  Schofield JPR; Burg D; Nicholas B; Strazzeri F; Brandsma J; Staykova D; Folisi C; Bansal AT; Xian Y; Guo Y; Rowe A; Corfield J; Wilson S; Ward J; Lutter R; Shaw DE; Bakke PS; Caruso M; Dahlen S-E; Fowler SJ; Horvath I; Howarth P; Krug N; Montuschi P; Sanak M; Sandstrom T; Sun K; Pandis I; Riley J; Auffray C; De Meulder B; Lefaudeux D; Sousa AR; Adcock IM; Chung KF; Sterk PJ; Skipp PJ; Djukanovic R; Ahmed H; Allen D; Badorrek P; Ballereau S; Baribaud F; Batuwitage MK; Bedding A; Behndig AF; Berglind A; Berton A; Bigler J; Boedigheimer MJ; Bonnelykke K; Brinkman P; Bush A; Campagna D; Casaulta C; Chaiboonchoe A; Davison T; De Meulder B; Delin I; Dennison P; Dodson P; El Hadjam L; Erzen D; Faulenbach C; Fichtner K; Fitch N; Formaggio E; Gahlemann M; Galffy G; Garissi D; Garret T; Gent J; Guillmant-Farry E; Henriksson E; Hoda U; Hohlfeld JM; Hu X; James A; Johnson K; Jullian N; Kerry G; Klueglich M; Knowles R; Konradsen JR; Kretsos K; Krueger L; Lantz A-S; Larminie C; Latzin P; Lefaudeux D; Lemonnier N; Lowe LA; Lutter R; Manta A; Mazein A; McEvoy L; Menzies-Gow A; Mores N; Murray CS; Nething K; Nihlen U; Niven R; Nordlund B; Nsubuga S; Pellet J; Pison C; Pratico G; Puig Valls M; Riemann K; Rocha JP; Rossios C; Santini G; Saqi M; Scott S; Sehgal N; Selby A; Soderman P; Sogbesan A; Spycher F; Stephan S; Stokholm J; Sunther M; Szentkereszty M; Tamasi L; Tariq K; Valente S; van Aalderen WM; van Drunen CM; Van Eyll J; Vyas A; Yu W; Zetterquist W; Zolkipli Z; Zwinderman AH; Adriaens N; Aliprantis A; Alving K; Bakke P; Balgoma D; Barber C; Baribaud F; Bates S; Bautmans A; Beleta J; Bochenek G; Brandsma J; Braun A; Burg D; Carayannopoulos L; Rocha JPCDP; Chaleckis R; D'Amico A; De Alba J; De Lepeleire I; Dekker T; Dijkhuis A; Draper A; Edwards J; Emma R; Ericsson M; Flood B; Gallart H; Gomez C; Gove K; Gozzard N; Haughney J; Hewitt L; Hohlfeld J; Holweg C; Hu R; Hu S; Kamphuis J; Kennington EJ; Kerry D; Knobel H; Kolmert J; Kots M; Kuo S; Kupczyk M; Lambrecht B; Lone-Latif S; Loza MJ; Marouzet L; Martin J; Masefield S; Mathon C; Meah S; Meiser A; Metcalf L; Mikus M; Miralpeix M; Monk P; Naz S; Nicholas B; Nilsson P; Ostling J; Pacino A; Palkonen S; Pavlidis S; Pennazza G; Petren A; Pink S; Postle A; Powell P; Rahman-Amin M; Rao N; Ravanetti L; Ray E; Reinke S; Reynolds L; Riley J; Robberechts M; Roberts A; Russell K; Rutgers M; Santoninco M; Schoelch C; Schofield JPR; Sjodin M; Skipp PJ; Smids B; Smith C; Smith J; Smith KM; Staykova D; Sun K; Thorngren J-O; Thornton B; Thorsen J; van de Pol M; van Geest M; Versnel J; Vink A; Wald F; Walker S; Ward J; Weiszhart Z; Wetzel K; Wheelock CE; Wiegman C; Williams S; Wilson SJ; Woodcock A; Yang X; Yeyasingham E; Prins J-B; Gahlemann M; Visintin L; Evans H; Puhl M; Buzermaniene L; Hudson V; Bond L; de Boer P; Widdershoven G; Sigmund R; Roberts A; Supple D; Hamerlijnck D; Negus J; Kamphuis J; Sergison L; Visintin L; de Boer P; Onstein S; MacNee W; Bernardini R; Bont L; Wecksell P-A; de Boer P; Gahlemann M; Sigmund R
• Article: ELIFE. 2019;8:e43578

  Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'

  Landegren N; Rosen LB; Freyhult E; Eriksson D; Fall T; Smith G; Ferre EMN; Brodin P; Sharon D; Snyder M; Lionakis M; Anderson M; Kampe O
• Letter: IMMUNITY. 2019;50(6):1335-1336

  A Call for Blood-In Human Immunology

  Brodin P; Duffy D; Quintana-Murci L
• Article: BLOOD. 2019;133(23):2465-2477

  Recommendations for the management of hemophagocytic lymphohistiocytosis in adults

  La Rosee P; Horne A; Hines M; Greenwood TVB; Machowicz R; Berliner N; Birndt S; Gil-Herrera J; Girschikofsky M; Jordan MB; Kumar A; van Laar JAM; Lachmann G; Nichols KE; Ramanan AV; Wang Y; Wang Z; Janka G; Henter J-I
• Article: JOURNAL OF IMMUNOLOGY. 2019;202(11):3143-3150

  Citrullination Controls Dendritic Cell Transdifferentiation into Osteoclasts

  Krishnamurthy A; Ytterberg AJ; Sun M; Sakuraba K; Steen J; Joshua V; Tarasova NK; Malmstrom V; Wahamaa H; Rethi B; Catrina AI
• Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2019;190:44-53

  Modulation of exercise training related adaptation of body composition and regulatory pathways by anabolic steroids

  Reitzner SM; Hengevoss J; Isenmann E; Diel P
• Letter: EUROPEAN RESPIRATORY JOURNAL. 2019;53(6):1900453

  Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

  Perotin J-M; Schofield JPR; Wilson SJ; Ward J; Brandsma J; Strazzeri F; Bansal A; Yang X; Rowe A; Corfield J; Lutter R; Shaw DE; Bakke PS; Caruso M; Dahlen B; Fowler SJ; Horvath I; Howarth P; Krug N; Montuschi P; Sanak M; Sandstrom T; Sun K; Pandis I; Auffray C; De Meulder B; Lefaudeux D; Riley JH; Sousa AR; Dahlen S-E; Adcock IM; Chung KF; Sterk PJ; Skipp PJ; Collins JE; Davies DE; Djukanovic R; Adcock IM; Ahmed H; Auffray C; Bakke P; Banssal AT; Baribaud F; Bates S; Bel EH; Bigler J; Bisgaard H; Boedigheimer MJ; Bonnelykke K; Brandsma J; Brinkman P; Bucchioni E; Burg D; Bush A; Caruso M; Chaiboonchoe A; Chanez P; Chung KF; Compton CH; Corfield J; D'Amico A; Dahlen SE; De Meulder B; Djukanovic R; Erpenbeck VJ; Erzen D; Fichtner K; Fitch N; Fleming LJ; Formaggio E; Fowler SJ; Frey U; Gahlemann M; Geiser T; Guo Y; Hashimoto S; Haughney J; Hedlin G; Hekking PW; Higenbottam T; Hohlfeld JM; Holweg C; Horvath I; Howarth P; James AJ; Knowles R; Knox AJ; Krug N; Lefaudeux D; Loza MJ; Lutter R; Manta A; Masefield S; Matthews JG; Mazein A; Meiser A; Middelveld RJM; Miralpeix M; Montuschi P; Mores N; Murray CS; Musial J; Myles D; Pahus L; Pandis I; Pavlidis S; Powell P; Pratico G; Puig Valls M; Rao N; Riley J; Roberts A; Roberts G; Rowe A; Sandstrom T; Seibold W; Selby A; Shaw DE; Sigmund R; Singer F; Skipp PJ; Sousa AR; Sterk PJ; Sun K; Thornton B; van Aalderen WM; van Geest M; Vestbo J; Vissing NH; Wagener AH; Wagers SS; Weiszhart Z; Wheelock CE; Wilson SJ; Aliprantis A; Allen D; Alving K; Badorrek P; Balgoma D; Ballereau S; Barber C; Batuwitage MK; Bautmans A; Bedding A; Behndig AF; Beleta J; Berglind A; Berton A; Bochenek G; Braun A; Campagna D; Carayannopoulos L; Casaulta C; Chaleckis R; Dahlen B; Davison T; De Alba J; De Lepeleire I; Dekker T; Delin I; Dennison P; Dijkhuis A; Dodson P; Dyson K; Edwards J; El Hadjam L; Emma R; Ericsson M; Faulenbach C; Flood B; Galffy G; Gallart H; Garissi D; Gent J; de Verdier MG; Gibeon D; Gomez C; Gove K; Guillmant-Farry E; Henriksson E; Hewitt L; Hoda U; Hu R; Hu S; Hu X; Jeyasingham E; Johnson K; Jullian N; Kamphuis J; Kennington EJ; Kerry D; Kerry G; Klueglich M; Knobel H; Kolmert J; Konradsen JR; Kots M; Kretsos K; Krueger L; Kuo S; Kupczyk M; Lambrecht B; Lantz A-S; Larminie C; Larsson LX; Latzin P; Lazarinis N; Lemonnier N; Lone-Latif S; Lowe LA; Manta A; Marouzet L; Martin J; Mathon C; McEvoy L; Meah S; Menzies-Gow A; Metcalf L; Mikus M; Monk P; Naz S; Nething K; Nicholas B; Nihlen U; Nilsson P; Niven R; Nordlund B; Nsubuga S; Ostling J; Pacino A; Palkonen S; Pellet J; Pennazza G; Petren A; Pink S; Pison C; Postle A; Rahman-Amin M; Ravanetti L; Ray E; Reinke S; Reynolds L; Riemann K; Robberechts M; Rocha JP; Rossios C; Russell K; Rutgers M; Santini G; Santoninco M; Saqi M; Schoelch C; Schofield JPR; Scott S; Sehgal N; Sjodin M; Smids B; Smith C; Smith J; Smith KM; Soderman P; Sogbessan A; Spycher F; Staykova D; Stephan S; Stokholm J; Strandberg K; Sunther M; Szentkereszty M; Tamasi L; Tariq K; Thorngren J-O; Thorsen J; Valente S; van de Pol M; van Drunen CM; Van Eyll J; Versnel J; Vink A; von Garnier C; Vyas A; Wald F; Walker S; Ward J; Wetzel K; Wiegman C; Williams S; Yang X; Yeyasingham E; Yu W; Zetterquist W; Zolkipli Z; Zwinderman AH; Prins J-B; Gahlemann M; Visintin L; Evans H; Puhl M; Buzermaniene L; Hudson V; Bond L; de Boer P; Widdershoven G; Sigmund R; Roberts A; Supple D; Hamerlijnck D; Negus J; Kamphuis J; Sergison L; Visintin L; de Boer P; Onstein S; MacNee W; Bernardini R; Bont L; Wecksell P-A; de Boer P; Gahlemann M; Sigmund R; Draper A; Gozzard N
• Doctoral thesis: 2019

  Cellular and molecular factors in the pathogenesis of systemic autoimmunity and comorbidities

  Ivanchenko, Margarita
• Article: JCI INSIGHT. 2019;4(9):126492

  B cell profiling in malaria reveals expansion and remodeling of CD11c⁺ B cell subsets

  Sundling C; Ronnberg C; Yman V; Asghar M; Jahnmatz P; Lakshmikanth T; Chen Y; Mikes J; Forsell MN; Sonden K; Achour A; Brodin P; Persson KEM; Farnert A
• Article: NATURE MEDICINE. 2019;25(4):591-596

  The repertoire of maternal anti-viral antibodies in human newborns

  Pou C; Nkulikiyimfura D; Henckel E; Olin A; Lakshmikanth T; Mikes J; Wang J; Chen Y; Bernhardsson AK; Gustafsson A; Bohlin K; Brodin P
• Review: FEBS JOURNAL. 2019;286(8):1514-1522

  The biology of the cell - insights from mass cytometry

  Brodin P
• Letter: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2019;195(3):305-309

  FoxP3⁺CXCR5⁺CD4⁺ T cell frequencies are increased in peripheral blood of patients with primary Sjogren's syndrome

  Ivanchenko M; Aqrawi LA; Bjork A; Wahren-Herlenius M; Chemin K
• Article: JCI INSIGHT. 2019;4(3):e125442

  Mass cytometry identifies distinct CD4⁺ T cell clusters distinguishing HIV-1-infected patients according to antiretroviral therapy initiation

  Bekele Y; Lakshmikanth T; Chen Y; Mikes J; Nasi A; Petkov S; Hejdeman B; Brodin P; Chiodi F
• Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2019;49(2):155-162

  Fixed airflow obstruction relates to eosinophil activation in asthmatics

  Mogensen I; Alving K; Dahlen S-E; James A; Forsberg B; Ono J; Ohta S; Venge P; Borres MP; Izuhara K; Janson C; Malinovschi A
• Letter: ALLERGY. 2019;74(2):406-411

  Treatable traits in the European U-BIOPRED adult asthma cohorts

  Simpson AJ; Hekking P-P; Shaw DE; Fleming LJ; Roberts G; Riley JH; Bates S; Sousa AR; Bansal AT; Pandis I; Sun K; Bakke PS; Caruso M; Dahlen B; Dahlen S-E; Horvath I; Krug N; Montuschi P; Sandstrom T; Singer F; Adcock IM; Wagers SS; Djukanovic R; Chung KF; Sterk PJ; Fowler SJ; Adcock IM; Ahmed H; Auffray C; Bakke P; Bansal AT; Baribaud F; Bates S; Bel EH; Bigler J; Bisgaard H; Boedigheimer MJ; Bonnelykke K; Brandsma J; Brinkman P; Bucchioni E; Burg D; Bush A; Caruso M; Chaiboonchoe A; Chanez P; Chung FK; Compton CH; Corfield J; D'Amico A; Dahlen B; Dahlen SE; De Meulder B; Djukanovic R; Erpenbeck VJ; Erzen D; Fichtner K; Fitch N; Fleming LJ; Formaggio E; Fowler SJ; Frey U; Gahlemann M; Geiser T; Goss V; Guo Y; Hashimoto S; Haughney J; Hedlin G; Hekking PW; Higenbottam T; Hohlfeld JM; Holweg C; Horvath I; Howarth P; James AJ; Knowles R; Knox AJ; Krug N; Lefaudeux D; Loza MJ; Lutter R; Manta A; Masefield S; Matthews JG; Mazein A; Meiser A; Middelveld RJM; Miralpeix M; Montuschi P; Mores N; Murray CS; Musial J; Myles D; Pahus L; Pandis I; Pavlidis S; Postle A; Powel P; Pratico G; Puig Valls M; Rao N; Riley J; Roberts A; Roberts G; Rowe A; Sandstrom T; Schofield JPR; Seibold W; Selby A; Shaw DE; Sigmund R; Singer F; Skipp PJ; Sousa AR; Sterk PJ; Sun K; van Aalderen WM; van Geest M; Vestbo J; Vissing NH; Wagener AH; Wagers SS; Weiszhart Z; Wheelock CE; Wilson SJ
• Editorial comment: NATURE REVIEWS IMMUNOLOGY. 2019;19(2):87-88

  Systems-level patterns emerge

  Brodin P
• Article: EBIOMEDICINE. 2019;40:517-527

  B cell alterations during BAFF inhibition with belimumab in SLE

  Ramskold D; Parodis I; Lakshmikanth T; Sippl N; Khademi M; Chen Y; Zickert A; Mikes J; Achour A; Amara K; Piehl F; Brodin P; Gunnarsson I; Malmstrom V
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(2):577-590

  Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

  Jevnikar Z; Ostling J; Calven J; Thorn K; Israelsson E; Oberg L; Singhania A; Lau LCK; Wilson SJ; Ward JA; Chauhan A; Sousa AR; De Meulder B; Loza MJ; Baribaud F; Sterk PJ; Chung KF; Sun K; Guo Y; Adcock IM; Payne D; Dahlen B; Chanez P; Shaw DE; Krug N; Hohlfeld JM; Sandstrom T; Djukanovic R; James A; Hinks TSC; Howarth PH; Vaarala O; van Geest M; Olsson H
• Article: METHODS IN MOLECULAR BIOLOGY. 2019;1989:111-123

  Automated Cell Processing for Mass Cytometry Experiments.

  Mikes J; Olin A; Lakshmikanth T; Chen Y; Brodin P
• Article: METHODS IN MOLECULAR BIOLOGY. 2019;1913:33-48

  Systems-Level Immune Monitoring by Mass Cytometry.

  Lakshmikanth T; Brodin P
• Article: RMD OPEN. 2019;5(2):e001055

  Juvenile idiopathic arthritis and risk of cancer before and after the introduction of biological therapies

  Horne A; Delcoigne B; Palmblad K; Askling J
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2019;89(1):e12732

  Effect of CTLA4-Ig (abatacept) treatment on T cells and B cells in peripheral blood of patients with polymyositis and dermatomyositis

  Tang Q; Ramskold D; Krystufkova O; Mann HF; Wick C; Dastmalchi M; Lakshmikanth T; Chen Y; Mikes J; Alexanderson H; Achour A; Brodin P; Vencovsky J; Lundberg IE; Malmstrom V
• Article: ARTHRITIS RESEARCH & THERAPY. 2018;20(1):285

  Pharmacovigilance in juvenile idiopathic arthritis patients treated with biologic or synthetic drugs: combined data of more than 15,000 patients from Pharmachild and national registries

  Swart J; Giancane G; Horneff G; Magnusson B; Hofer M; Alexeeva E; Panaviene V; Bader-Meunier B; Anton J; Nielsen S; De Benedetti F; Kamphuis S; Stanevica V; Tracahana M; Ailioaie LM; Tsitsami E; Klein A; Minden K; Foeldvari I; Haas JP; Klotsche J; Horne AC; Consolaro A; Bovis F; Bagnasco F; Pistorio A; Martini A; Wulffraat N; Ruperto N
• Letter: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(12):1840-1842

  Clinical associations and expression pattern of the autoimmunity susceptibility factor DIORA-1 in patients with primary Sjogren's syndrome

  Aqrawi LA; Mentlein L; Meneghel L; Bjork A; Thorlacius GE; Ivanchenko M; Sepulveda JIR; Skarstein K; Kvarnstrom M; Brauner S; Espinosa A; Wahren-Herlenius M
• Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2018;194(3):315-326

  The Sjogren's syndrome-associated autoantigen Ro52/TRIM21 modulates follicular B cell homeostasis and immunoglobulin production

  Brauner S; Ivanchenko M; Thorlacius GE; Ambrosi A; Wahren-Herlenius M
• Article: NEUROGASTROENTEROLOGY AND MOTILITY. 2018;30(11):e13436

  Pre- and perinatal stress and irritable bowel syndrome in young adults - A nationwide register-based cohort study

  Olen O; Stephansson O; Backman A-S; Tornblom H; Simren M; Altman M
• Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2018;33(10):1011-1020

  Moderate neonatal hypoglycemia and adverse neurological development at 2-6 years of age

  Wickstrom R; Skiold B; Petersson G; Stephansson O; Altman M
• Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2018;48(9):1147-1154

  IgE sensitization to food allergens and airborne allergens in relation to biomarkers of type 2 inflammation in asthma

  Patelis A; Alving K; Middelveld R; James A; Ono J; Ohta S; Izuhara K; Borres MP; Forsberg B; Janson C; Malinovschi A
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2018;6(5):1508-1517

  Recommendations for the Use of Etoposide-Based Therapy and Bone Marrow Transplantation for the Treatment of HLH: Consensus Statements by the HLH Steering Committee of the Histiocyte Society

  Ehl S; Astigarraga I; Greenwood TVB; Hines M; Horne A; Ishii E; Janka G; Jordan MB; La Rosee P; Lehmberg K; Machowicz R; Nichols KE; Sieni E; Wang Z; Henter J-I
• Article: CELL. 2018;174(5):1277-1292.e14

  Stereotypic Immune System Development in Newborn Children

  Olin A; Henckel E; Chen Y; Lakshmikanth T; Pou C; Mikes J; Gustafsson A; Bernhardsson AK; Zhang C; Bohlin K; Brodin P
• Article: CLINICAL IMMUNOLOGY. 2018;193:70-79

  Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains

  Ju C-H; Blum LK; Kongpachith S; Lingampalli N; Mao R; Brodin P; Dekker CL; Davis MM; Robinson WH
• Article: ERJ OPEN RESEARCH. 2018;4(3):33-2018

  Altered Fc galactosylation in IgG4 is a potential serum marker for chronic lung disease

  Heyder T; Wiklundh E; Eklund A; James A; Dahlen S-E; Grunewald J; Zubarev RA; Lundström SL
• Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2018;192(3):259-270

  Diminished CXCR5 expression in peripheral blood of patients with Sjogren's syndrome may relate to both genotype and salivary gland homing

  Aqrawi LA; Ivanchenko M; Bjork A; Sepulveda JIR; Imgenberg-Kreuz J; Kvarnstrom M; Haselmayer P; Jensen JL; Nordmark G; Chemin K; Skarstein K; Wahren-Herlenius M
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2018;50(5S):845

  Expression Of Markers Of Browning In White Adipose Tissue In Life-long Endurance Trained Athletes

  Reitzner SM; Kissling S; Chapman M; Sundberg CJ
• Review: ANNUAL REVIEW OF IMMUNOLOGY. 2018;36:843-864

  Rebooting Human Immunology

  Davis MM; Brodin P
• Letter: CLINICAL AND EXPERIMENTAL ALLERGY. 2018;48(4):475-478

  IL-6 pathway upregulation in subgroup of severe asthma is associated with neutrophilia and poor lung function

  Turan N; Edwards MJ; Bates S; Shaw D; Chung KF; Loza MJ; James A; Van Oosterhout A
• Article: PHYSIOLOGICAL REPORTS. 2018;6(5):e13624

  Expression of striated activator of rho-signaling in human skeletal muscle following acute exercise and long-term training

  Reitzner SM; Norrbom J; Sundberg CJ; Gidlund E-K
• Article: CELL METABOLISM. 2018;27(2):378-392.e5

  Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation

  Agudelo LZ; Ferreira DMS; Cervenka I; Bryzgalova G; Dadvar S; Jannig PR; Pettersson-Klein AT; Lakshmikanth T; Sustarsic EG; Porsmyr-Palmertz M; Correia JC; Izadi M; Martinez-Redondo V; Ueland PM; Midttun O; Gerhart-Hines Z; Brodin P; Pereira T; Berggren P-O; Ruas JL
• Article: SCIENTIFIC REPORTS. 2018;8(1):28

  Discovering viral genomes in human metagenomic data by predicting unknown protein families

  Barrientos-Somarribas M; Messina DN; Pou C; Lysholm F; Bjerkner A; Allander T; Andersson B; Sonnhammer ELL
• Article: FRONTIERS IN MOLECULAR BIOSCIENCES. 2018;5:81

  Continuous Immune Cell Differentiation Inferred From Single-Cell Measurements Following Allogeneic Stem Cell Transplantation

  Chen Y; Lakshmikanth T; Olin A; Mikes J; Remberger M; Brodin P
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2018;50(5):845

  Expression Of Markers Of Browning In White Adipose Tissue In Life-long Endurance Trained Athletes

  Reitzner SM; Kissling S; Chapman M; Sundberg CJ
• Article: BLOOD. 2017;130(25):2728-2738

  Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study

  Bergsten E; Horne A; Arico M; Astigarraga I; Egeler RM; Filipovich AH; Ishii E; Janka G; Ladisch S; Lehmberg K; McClain KL; Minkov M; Montgomery S; Nanduri V; Rosso D; Henter J-I
• Article: SCIENTIFIC REPORTS. 2017;7(1):16327

  STRT-seq-2i: dual-index 5′ single cell and nucleus RNA-seq on an addressable microwell array

  Hochgerner H; Lonnerberg P; Hodge R; Mikes J; Heskol A; Hubschle H; Lin P; Picelli S; La Manno G; Ratz M; Dunne J; Husain S; Lein E; Srinivasan M; Zeisel A; Linnarsson S
• Article: ALLERGY. 2017;72(11):1753-1760

  Serum periostin relates to type-2 inflammation and lung function in asthma: Data from the large population-based cohort Swedish GA(2)LEN

  James A; Janson C; Malinovschi A; Holweg C; Alving K; Ono J; Ohta S; Ek A; Middelveld R; Dahlen B; Forsberg B; Izuhara K; Dahlen S-E
• Article: JOURNAL OF AUTOIMMUNITY. 2017;84:29-45

  Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis

  Gronwall C; Amara K; Hardt U; Krishnamurthy A; Steen J; Engstrom M; Sun M; Ytterberg AJ; Zubarev RA; Scheel-Toellner D; Greenberg JD; Klareskog L; Catrina AI; Malmstrom V; Silverman GJ
• Article: JOURNAL OF PEDIATRICS. 2017;189:72-78.e3

  Development and Initial Validation of the Macrophage Activation Syndrome/Primary Hemophagocytic Lymphohistiocytosis Score, a Diagnostic Tool that Differentiates Primary Hemophagocytic Lymphohistiocytosis from Macrophage Activation Syndrome

  Minoia F; Bovis F; Davi S; Insalaco A; Lehmberg K; Shenoi S; Weitzman S; Espada G; Gao Y-J; Anton J; Kitoh T; Kasapcopur O; Sanner H; Merino R; Astigarraga I; Alessio M; Jeng M; Chasnyk V; Nichols KE; Zeng H; Li C; Micalizzi C; Ruperto N; Martini A; Cron RQ; Ravelli A; Horne A
• Article: JOURNAL OF ORAL & FACIAL PAIN AND HEADACHE. 2017;31(4):353-361

  Parenting a Child with Juvenile Idiopathic Arthritis, Orofacial Pain, and Dysfunction: A Qualitative Study

  Leksell E; Hallberg U; Horne A; Ernberg M; Hedenberg-Magnusson B
• Article: PEDIATRIC PULMONOLOGY. 2017;52(9):1179-1186

  Differences and similarities between bronchopulmonary dysplasia and asthma in schoolchildren

  Nordlund B; James A; Ebersjo C; Hedlin G; Brostrom EB
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(3):135-142

  The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education

  Ganesan S; Luu TT; Chambers BJ; Meinke S; Brodin P; Vivier E; Wetzel DM; Koleske AJ; Kadri N; Hoglund P
• Article: CELL REPORTS. 2017;20(9):2238-2250

  Mass Cytometry and Topological Data Analysis Reveal Immune Parameters Associated with Complications after Allogeneic Stem Cell Transplantation

  Lakshmikanth T; Olin A; Chen Y; Mikes J; Fredlund E; Remberger M; Omazic B; Brodin P
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(30):E6097-E6106

  Continuous immunotypes describe human immune variation and predict diverse responses

  Kaczorowski KJ; Shekhar K; Nkulikiyimfura D; Dekker CL; Maecker H; Davis MM; Chakraborty AK; Brodin P
• Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2017;47(7):909-917

  Assessment of in vivo mast cell reactivity in patients with systemic mastocytosis

  Gulen T; Westerberg CM; Lyberg K; Ekoff M; Kolmert J; Bood J; Ohd J; James A; Dahlen S-E; Nilsson G; Dahlen B
• Article: NATURE COMMUNICATIONS. 2017;8:15627

  Expression of CD226 is associated to but not required for NK cell education

  Wagner AK; Kadri N; Snall J; Brodin P; Gilfillan S; Colonna M; Bernhardt GN; Hoglund P; Karre K; Chambers BJ
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2017;49(5S):1087

  Acute Exercise Increases STARS mRNA in Human Skeletal Muscle

  Reitzner S; Gidlund E-K; Sundberg CJ
• Article: SCIENTIFIC REPORTS. 2017;7:43989

  Immunogenicity is preferentially induced in sparse dendritic cell cultures

  Nasi A; Bollampalli VP; Sun M; Chen Y; Amu S; Nylen S; Eidsmo L; Rothfuchs AG; Rethi B
• Editorial comment: CELL HOST & MICROBE. 2017;21(3):309-310

  Life-Saving Degeneracy in the Human Immune System

  Brodin P
• Article: JOURNAL OF PERINATOLOGY. 2017;37(3):236-242

  Durations of second stage of labor and pushing, and adverse neonatal outcomes: a population-based cohort study

  Sandstrom A; Altman M; Cnattingius S; Johansson S; Ahlberg M; Stephansson O
• Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2017;28(1):79-85

  A longitudinal assessment of circulating YKL-40 levels in preschool children with wheeze

  James A; Hammar KS; Reinius L; Konradsen JR; Dahlen S-E; Soderhall C; Hedlin G
• Review: CURRENT TREATMENT OPTIONS IN NEUROLOGY. 2017;19(1):3

  How to Treat Involvement of the Central Nervous System in Hemophagocytic Lymphohistiocytosis?

  Horne A; Wickstrom R; Jordan MB; Yeh EA; Naqvi A; Henter J-I; Janka G
• Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1130

  Mass Cytometry Identifies Distinct Lung CD4⁺ T Cell Patterns in Lofgren's Syndrome and Non-Lofgren's Syndrome Sarcoidosis

  Kaiser Y; Lakshmikanth T; Chen Y; Mikes J; Eklund A; Brodin P; Achour A; Grunewald J
• Article: FRONTIERS IN IMMUNOLOGY. 2017;8:717

  Combining Flow and Mass Cytometry in the Search for Biomarkers in Chronic Graft-versus-Host Disease

  Stikvoort A; Chen Y; Radestad E; Torlen J; Lakshmikanth T; Bjorklund A; Mikes J; Achour A; Gertow J; Sundberg B; Remberger M; Sundin M; Mattsson J; Brodin P; Uhlin M
• Review: NATURE REVIEWS IMMUNOLOGY. 2017;17(1):21-29

  Human immune system variation

  Brodin P; Davis MM
• Article: ALLERGY. 2016;71(12):1728-1735

  Rhinovirus-specific antibody responses in preschool children with acute wheeze reflect severity of respiratory symptoms

  Stenberg-Hammar K; Niespodziana K; Soederhaell C; James A; Cabauatan CR; Konradsen JR; Melen E; van Hage M; Valenta R; Hedlin G
• Article: BRITISH JOURNAL OF CANCER. 2016;115(8):1008-1014

  Virome characterisation from Guthrie cards in children who later developed acute lymphoblastic leukaemia

  Bogdanovic G; Pou C; Barrientos-Somarribas M; Bjerkner A; Honkaniemi E; Allander T; Andersson B; Gustafsson B
• Article: RETROVIROLOGY. 2016;13(1):51

  Lack of concordance between residual viremia and viral variants driving de novo infection of CD4⁺ T cells on ART

  Puertas MC; Noguera-Julian M; Massanella M; Pou C; Buzon MJ; Clotet B; Stevenson M; Paredes R; Blanco J; Martinez-Picado J
• Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46(7):1758-1769

  In vivo engineering of mobilized stem cell grafts with the immunomodulatory drug FTY720 for allogeneic transplantation

  Lakshmikanth T; Heuts F; Muvva SSVJR; Wallin RPA; Persson A-K; Fauriat C; Applequist SE; Ljunggren H-G; Hoglund P; Karre K; Svensson M; Juarez JG
• Review: BLOOD. 2016;127(22):2672-2681

  Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages

  Emile J-F; Abla O; Fraitag S; Horne A; Haroche J; Donadieu J; Requena-Caballero L; Jordan MB; Abdel-Wahab O; Allen CE; Charlotte F; Diamond EL; Egeler RM; Fischer A; Gil Herrera J; Henter J-I; Janku F; Merad M; Picarsic J; Rodriguez-Galindo C; Rollins BJ; Tazi A; Vassallo R; Weiss LM
• Review: NATURE REVIEWS RHEUMATOLOGY. 2016;12(5):259-268

  Macrophage activation syndrome in the era of biologic therapy

  Grom AA; Horne A; De Benedetti F
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(4):721-729

  Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss

  Krishnamurthy A; Joshua V; Hensvold AH; Jin T; Sun M; Vivar N; Ytterberg AJ; Engstrom M; Fernandes-Cerqueira C; Amara K; Magnusson M; Wigerblad G; Kato J; Jimenez-Andrade JM; Tyson K; Rapecki S; Lundberg K; Catrina S-B; Jakobsson P-J; Svensson C; Malmstrom V; Klareskog L; Wahamaa H; Catrina AI
• Review: TRENDS IN IMMUNOLOGY. 2016;37(3):233-243

  Immune Adaptation to Environmental Influence: The Case of NK Cells and HCMV

  Roelle A; Brodin P
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(3):481-489

  2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative

  Ravelli A; Minoia F; Davi S; Horne A; Bovis F; Pistorio A; Arico M; Avcin T; Behrens EM; De Benedetti F; Filipovic L; Grom AA; Henter J-I; Ilowite NT; Jordan MB; Khubchandani R; Kitoh T; Lehmberg K; Lovell DJ; Miettunen P; Nichols KE; Ozen S; Schmid JP; Ramanan AV; Russo R; Schneider R; Sterba G; Uziel Y; Wallace C; Wouters C; Wulffraat N; Demirkaya E; Brunner HI; Martini A; Ruperto N; Cron RQ
• Article: ARTHRITIS & RHEUMATOLOGY. 2016;68(3):566-576

  2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative

  Ravelli A; Minoia F; Davi S; Horne A; Bovis F; Pistorio A; Arico M; Avcin T; Behrens EM; De Benedetti F; Filipovic L; Grom AA; Henter J-I; Ilowite NT; Jordan MB; Khubchandani R; Kitoh T; Lehmberg K; Lovell DJ; Miettunen P; Nichols KE; Ozen S; Schmid JP; Ramanan AV; Russo R; Schneider R; Sterba G; Uziel Y; Wallace C; Wouters C; Wulffraat N; Demirkaya E; Brunner HI; Martini A; Ruperto N; Cron RQ
• Article: CANCER IMMUNOLOGY RESEARCH. 2016;4(2):113-123

  Retuning of Mouse NK Cells after Interference with MHC Class I Sensing Adjusts Self-Tolerance but Preserves Anticancer Response

  Wagner AK; Wickstrom SL; Tallerico R; Salam S; Lakshmikanth T; Brauner H; Hoglund P; Carbone E; Johansson MH; Karre K
• Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193(2):131-142

  Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease

  James AJ; Reinius LE; Verhoek M; Gomes A; Kupczyk M; Hammar U; Ono J; Ohta S; Izuhara K; Bel E; Kere J; Soderhall C; Dahlen B; Boot RG; Dahlen S-E
• Review: CURRENT TREATMENT OPTIONS IN ALLERGY. 2016;3(4):439-452

  Biomarkers for the Phenotyping and Monitoring of Asthma in Children.

  James A; Hedlin G
• Article: RMD OPEN. 2016;2(1):e000161

  Expert consensus on dynamics of laboratory tests for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis

  Ravelli A; Minoia F; Davi S; Horne A; Bovis F; Pistorio A; Arico M; Avcin T; Behrens EM; De Benedetti F; Filipovic A; Grom AA; Henter J-I; Ilowite NT; Jordan MB; Khubchandani R; Kitoh T; Lehmberg K; Lovell DJ; Miettunen P; Nichols KE; Ozen S; Schmid JP; Ramanan AV; Russo R; Schneider R; Sterba G; Uziel Y; Wallace C; Wouters C; Wulffraat N; Demirkaya E; Brunner HI; Martini A; Ruperto N; Cron RQ
• Article: PLOS ONE. 2016;11(1):e0146687

  A Follow-Up of the Multicenter Collaborative Study on HIV-1 Drug Resistance and Tropism Testing Using 454 Ultra Deep Pyrosequencing.

  St John EP; Simen BB; Turenchalk GS; Braverman MS; Abbate I; Aerssens J; Bouchez O; Gabriel C; Izopet J; Meixenberger K; Di Giallonardo F; Schlapbach R; Paredes R; Sakwa J; Schmitz-Agheguian GG; Thielen A; Victor M; Metzner KJ; Däumer MP; 454 HIV-1 Alpha Study Group
• Editorial comment: IMMUNITY. 2015;43(6):1035-1037

  Powerful Populations Respond to Viruses and Vaccines

  Brodin P
• Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2015;26(8):772-779

  Predicting asthma morbidity in children using proposed markers of Th2-type inflammation

  Konradsen JR; Skantz E; Nordlund B; Lidegran M; James A; Ono J; Ohta S; Izuhara K; Dahlen S-E; Alving K; Hedlin G
• Article: HAEMATOLOGICA. 2015;100(11):1477-1485

  Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy

  Nakasone H; Remberger M; Tian L; Brodin P; Sahaf B; Wu F; Mattsson J; Lowsky R; Negrin R; Miklos DB; Meyer E
• Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2015;30(11):1209-1215

  Prolonged second stage of labor is associated with low Apgar score.

  Altman M; Sandström A; Petersson G; Frisell T; Cnattingius S; Stephansson O
• Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2015;70(10):2885-2888

  Primary resistance to integrase strand-transfer inhibitors in Europe.

  Casadellà M; van Ham PM; Noguera-Julian M; van Kessel A; Pou C; Hofstra LM; Santos JR; Garcia F; Struck D; Alexiev I; Bakken Kran AM; Hoepelman AI; Kostrikis LG; Somogyi S; Liitsola K; Linka M; Nielsen C; Otelea D; Paraskevis D; Poljak M; Puchhammer-Stöckl E; Staneková D; Stanojevic M; Van Laethem K; Zidovec Lepej S; Clotet B; Boucher CAB; Paredes R; Wensing AMJ; SPREAD programme
• Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2015;70(9):2639-2647

  Determinants of virological failure and antiretroviral drug resistance in Mozambique.

  Rupérez M; Pou C; Maculuve S; Cedeño S; Luis L; Rodríguez J; Letang E; Moltó J; Macete E; Clotet B; Alonso P; Menéndez C; Naniche D; Paredes R
• Article: PROSTAGLANDINS & OTHER LIPID MEDIATORS. 2015;121(Pt A):83-90

  On the biosynthesis of 15-HETE and eoxin C₄ by human airway epithelial cells

  Brunnstrom A; Tryselius Y; Feltenmark S; Andersson E; Leksell H; James A; Mannervik B; Dahlen B; Claesson H-E
• Article: JOURNAL OF INTERNAL MEDICINE. 2015;278(3):323-332

  Reduced expression of TRIM21/Ro52 predicts poor prognosis in diffuse large B-cell lymphoma patients with and without rheumatic disease

  Brauner S; Zhou W; Backlin C; Green TM; Folkersen L; Ivanchenko M; Lofstrom B; Xu-Monette ZY; Young KH; Pedersen LM; Moller MB; Sundstrom C; Enblad G; Baecklund E; Wahren-Herlenius M
• Article: JOURNAL OF HUMAN LACTATION. 2015;31(3):393-400

  Early Provision of Mother's Own Milk and Other Predictors of Successful Breast Milk Feeding after Very Preterm Birth: A Regional Observational Study

  Wilson E; Christensson K; Brandt L; Altman M; Bonamy A-K
• Article: AIDS. 2015;29(12):1493-1504

  Clinical value of ultradeep HIV-1 genotyping and tropism testing in late presenters with advanced disease.

  Casadellà M; Manzardo C; Noguera-Julian M; Ferrer E; Domingo P; Pérez-Álvarez S; Podzamczer D; Plana M; Clotet B; Gatell JM; Miró JM; Paredes R; ADVANZ and ADVANZ-3 Investigators
• Article: JOURNAL OF RHEUMATOLOGY. 2015;42(6):994-1001

  Dissecting the Heterogeneity of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis

  Minoia F; Davi S; Horne A; Bovis F; Demirkaya E; Akikusa J; Ayaz NA; Al-Mayouf SM; Barone P; Bica B; Bolt I; Breda L; De Cunto C; Enciso S; Gallizzi R; Griffin T; Hennon T; Horneff G; Jeng M; Kapovic AM; Lipton JM; Manzoni SM; Rumba-Rozenfelde I; Magalhaes CS; Sewairi WM; Stine KC; Vougiouka O; Weaver LK; Davidsone Z; De Inocencio J; Ioseliani M; Lattanzi B; Tezer H; Buoncompagni A; Picco P; Ruperto N; Martini A; Cron RQ; Ravelli A
• Article: ACTA PAEDIATRICA. 2015;104(3):259-263

  Perinatal conditions related to growth restriction and inflammation are associated with an increased risk of bronchopulmonary dysplasia

  Eriksson L; Haglund B; Odlind V; Altman M; Ewald U; Kieler H
• Article: PEDIATRIC BLOOD & CANCER. 2015;62(2):346-352

  Incidence and Clinical Presentation of Primary Hemophagocytic Lymphohistiocytosis in Sweden

  Meeths M; Horne A; Sabel M; Bryceson YT; Henter J-I
• Article: DIABETOLOGIA. 2015;58(2):346-354

  A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models

  Larsson PG; Lakshmikanth T; Laitinen OH; Utorova R; Jacobson S; Oikarinen M; Domsgen E; Koivunen MRL; Chaux P; Devard N; Lecouturier V; Almond J; Knip M; Hyoty H; Flodstrom-Tullberg M
• Article: CELL. 2015;160(1-2):37-47

  Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

  Brodin P; Jojic V; Gao T; Bhattacharya S; Angel CJL; Furman D; Shen-Orr S; Dekker CL; Swan GE; Butte AJ; Maecker HT; Davis MM
• Article: BMJ-BRITISH MEDICAL JOURNAL. 2014;349:g6572

  Maternal overweight and obesity in early pregnancy and risk of infant mortality: a population based cohort study in Sweden

  Johansson S; Villamor E; Altman M; Bonamy A-KE; Granath F; Cnattingius S
• Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(11):3160-3169

  Clinical Features, Treatment, and Outcome of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis A Multinational, Multicenter Study of 362 Patients

  Minoia F; Davi S; Horne A; Demirkaya E; Bovis F; Li C; Lehmberg K; Weitzman S; Insalaco A; Wouters C; Shenoi S; Espada G; Ozen S; Anton J; Khubchandani R; Russo R; Pal P; Kasapcopur O; Miettunen P; Maritsi D; Merino R; Shakoory B; Alessio M; Chasnyk V; Sanner H; Gao Y-J; Zeng H; Kitoh T; Avcin T; Fischbach M; Frosch M; Grom A; Huber A; Jelusic M; Sawhney S; Uziel Y; Ruperto N; Martini A; Cron RQ; Ravelli A
• Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2014;740:302-311

  Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle

  Manson ML; Safholm J; Al-Ameri M; Bergman P; Orre A-C; Sward K; James A; Dahlen S-E; Adner M
• Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(10):2871-2880

  Performance of Current Guidelines for Diagnosis of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis

  Davi S; Minoia F; Pistorio A; Horne A; Consolaro A; Rosina S; Bovis F; Cimaz R; Gamir ML; Ilowite NT; Kone-Paut I; Feitosa de Oliveira SK; McCurdy D; Silva CA; Sztajnbok F; Tsitsami E; Unsal E; Weiss JE; Wulffraat N; Abinun M; Aggarwal A; Apaz MT; Astigarraga I; Corona F; Cuttica R; D'Angelo G; Eisenstein EM; Hashad S; Lepore L; Mulaosmanovic V; Nielsen S; Prahalad S; Rigante D; Stanevicha V; Sterba G; Susic G; Takei S; Trauzeddel R; Zletni M; Ruperto N; Martini A; Cron RQ; Ravelli A
• Article: CLINICAL INFECTIOUS DISEASES. 2014;59(4):578-588

  Improved prediction of salvage antiretroviral therapy outcomes using ultrasensitive HIV-1 drug resistance testing.

  Pou C; Noguera-Julian M; Pérez-Álvarez S; García F; Delgado R; Dalmau D; Álvarez-Tejado M; Gonzalez D; Sayada C; Chueca N; Pulido F; Ibáñez L; Rodríguez C; Casadellà M; Santos JR; Ruiz L; Clotet B; Paredes R
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(2):306-313

  Effects of selective COX-2 inhibition on allergen-induced bronchoconstriction and airway inflammation in asthma

  Daham K; James A; Balgoma D; Kupczyk M; Billing B; Lindeberg A; Henriksson E; FitzGerald GA; Wheelock CE; Dahlen S-E; Dahlen B
• Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(2):475-478

  Bitter taste receptor (TAS2R) agonists inhibit IgE-dependent mast cell activation

  Ekoff M; Choi J-H; James A; Dahlen B; Nilsson G; Dahlen S-E
• Article: JOURNAL OF VIROLOGICAL METHODS. 2014;204:31-37

  An international multicenter study on HIV-1 drug resistance testing by 454 ultra-deep pyrosequencing.

  Simen BB; Braverman MS; Abbate I; Aerssens J; Bidet Y; Bouchez O; Gabriel C; Izopet J; Kessler HH; Stelzl E; Di Giallonardo F; Schlapbach R; Radonic A; Paredes R; Recordon-Pinson P; Sakwa J; St John EP; Schmitz-Agheguian GG; Metzner KJ; Däumer MP; 454 HIV Alphastudy Group
• Article: PEDIATRIC PULMONOLOGY. 2014;49(7):665-672

  Prenatal Inflammatory Risk Factors for Development of Bronchopulmonary Dysplasia

  Eriksson L; Haglund B; Odlind V; Altman M; Kieler H
• Letter: LAKARTIDNINGEN. 2014;111(11):494-495

  [23 physicians comments on circumcision of small boys: The Swedish Medical Association should take a more humble approach].

  Altman M; Altman D; Fischler B; Björkstén B; Bruchfeld A; Böhm F; Chrapkowska C; Finder M; Finkel Y; Halmin M; Heyman M; Ilicki A; Kahn R; Karpman D; Katz-Salamon M; Lagercrantz H; Mårtensson T; Nisell H; Rosling H; Sarman I; Wackernagel D; Wennergren G; Wilczek M
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(1):202-207

  Automatic Classification of Cellular Expression by Nonlinear Stochastic Embedding (ACCENSE)

  Shekhar K; Brodin P; Davis MM; Chakraborty AK
• Article: PEPTIDES. 2014;51:100-109

  Enhanced expression of neuropeptide S (NPS) receptor in eosinophils from severe asthmatics and subjects with total IgE above 100 IU/ml

  Ilmarinen P; James A; Moilanen E; Pulkkinen V; Daham K; Saarelainen S; Laitinen T; Dahlen S-E; Kere J; Dahlen B; Kankaanranta H
• Article: PLOS ONE. 2014;9(12):e111758

  Mechanical Stress Downregulates MHC Class I Expression on Human Cancer Cell Membrane

  La Rocca R; Tallerico R; Hassan AT; Das G; Tadepally L; Matteucci M; Liberale C; Mesuraca M; Scumaci D; Gentile F; Cojoc G; Perozziello G; Ammendolia A; Gallo A; Karre K; Cuda G; Candeloro P; Di Fabrizio E; Carbone E
• Article: VIROLOGY JOURNAL. 2013;10:350

  Stable HIV-1 integrase diversity during initial HIV-1 RNA decay suggests complete blockade of plasma HIV-1 replication by effective raltegravir-containing salvage therapy.

  Noguera-Julian M; Casadellà M; Pou C; Rodríguez C; Pérez-Álvarez S; Puig J; Clotet B; Paredes R
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;132(2):328-35.e5

  The chitinase-like protein YKL-40: A possible biomarker of inflammation and airway remodeling in severe pediatric asthma

  Konradsen JR; James A; Nordlund B; Reinius LE; Soderhall C; Melen E; Wheelock A; Carlsen KCL; Lidegran M; Verhoek M; Boot RG; Dahlen B; Dahlen SE; Hedlin G
• Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2013;51(8):2754-2757

  RECall for automated genotypic tropism testing.

  Pou C; Bellido R; Casadellà M; Puig T; Clotet B; Harrigan R; Paredes R
• Article: THORAX. 2013;68(7):611-618

  Detection of exacerbations in asthma based on electronic diary data: results from the 1-year prospective BIOAIR study

  Kupczyk M; Haque S; Sterk PJ; Nizankowska-Mogilnicka E; Papi A; Bel EH; Chanez P; Dahlen B; Gaga M; Gjomarkaj M; Howarth PH; Johnston SL; Joos GF; Kanniess F; Tzortzaki E; James A; Middelveld RJM; Dahlen S-E
• Article: EUROPEAN RESPIRATORY JOURNAL. 2013;42(1):65-78

  Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics

  Orsmark-Pietrast C; James A; Konradsen JR; Nordlund B; Soderhall C; Pulkkinen V; Pedroletti C; Daham K; Kupczyk M; Dahlen B; Kere J; Dahlen S-E; Hedlin G; Melen E
• Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2013;68(6):1382-1387

  Switching the third drug of antiretroviral therapy to maraviroc in aviraemic subjects: a pilot, prospective, randomized clinical trial.

  Bonjoch A; Pou C; Pérez-Álvarez N; Bellido R; Casadellà M; Puig J; Noguera-Julian M; Clotet B; Negredo E; Paredes R
• Article: RESPIRATORY RESEARCH. 2013;14(1):47

  Adhesion molecules in subjects with COPD and healthy non-smokers: a cross sectional parallel group study

  Blidberg K; Palmberg L; James A; Billing B; Henriksson E; Lantz A-S; Larsson K; Dahlen B
• Article: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2013;9(4):307-317

  Systems level immune response analysis and personalized medicine

  Brodin P; Valentini D; Uhlin M; Mattsson J; Zumla A; Maeurer MJ
• Article: DIABETOLOGIA. 2013;56(4):867-874

  Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice

  Larsson PG; Lakshmikanth T; Svedin E; King C; Flodstrom-Tullberg M
• Article: IMMUNOBIOLOGY. 2013;218(4):543-547

  HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Δ32/Δ32.

  Ballana E; Riveira-Munoz E; Pou C; Bach V; Parera M; Noguera M; Santos JR; Badia R; Casadellà M; Clotet B; Paredes R; Martínez MA; Brander C; Esté JA
• Article: PAEDIATRIC AND PERINATAL EPIDEMIOLOGY. 2013;27(2):172-181

  Risk Factors for Acute Respiratory Morbidity in Moderately Preterm Infants

  Altman M; Vanpee M; Cnattingius S; Norman M
• Article: TRAFFIC. 2013;14(2):205-218

  Multiple Sorting Systems for Secretory Granules Ensure the Regulated Secretion of Peptide Hormones

  Sun M; Watanabe T; Bochimoto H; Sakai Y; Torii S; Takeuchi T; Hosaka M
• Article: FRONTIERS IN IMMUNOLOGY. 2013;4:65

  Natural killer cell inhibitory receptor expression in humans and mice: a closer look

  Sternberg-Simon M; Brodin P; Pickman Y; Onfelt B; Karre K; Malmberg K-J; Hoglund P; Mehr R
• Article: PLOS ONE. 2013;8(8):e67085

  HIV-1 tropism testing in subjects achieving undetectable HIV-1 RNA: diagnostic accuracy, viral evolution and compartmentalization.

  Pou C; Codoñer FM; Thielen A; Bellido R; Pérez-Álvarez S; Cabrera C; Dalmau J; Curriu M; Lie Y; Noguera-Julian M; Puig J; Martínez-Picado J; Blanco J; Coakley E; Däumer M; Clotet B; Paredes R
• Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2013;162(2):135-142

  The Influence of Aspirin on Release of Eoxin C4, Leukotriene C4 and 15-HETE, in Eosinophilic Granulocytes Isolated from Patients with Asthma

  James A; Daham K; Backman L; Brunnstrom A; Tingvall T; Kumlin M; Edenius C; Dahlen S-E; Dahlen B; Claesson H-E
• Article: INTERNATIONAL JOURNAL OF HEMATOLOGY. 2012;96(6):798-800

  Major surgery in a neutropenic patient undergoing allogeneic stem cell transplantation for high risk myelofibrosis

  Brodin P; Gilg S; Lundell L; Mattsson J
• Editorial comment: ONCOIMMUNOLOGY. 2012;1(4):541-543

  A novel facet of tumor suppression by p53 Induction of tumor immunogenicity

  Li H; Lakshmikanth T; Carbone E; Selivanova G
• Article: ALLERGY. 2012;67(7):958-961

  Corticosteroid treatment selectively decreases mast cells in the smooth muscle and epithelium of asthmatic bronchi

  James A; Gyllfors P; Henriksson E; Dahlen SE; Adner M; Nilsson G; Dahlen B
• Article: ONCOGENESIS. 2012;1(3):e3

  MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma

  Sonkoly E; Loven J; Xu N; Meisgen F; Wei T; Brodin P; Jaks V; Kasper M; Shimokawa T; Harada M; Heilborn J; Hedblad M-A; Hippe A; Grander D; Homey B; Zaphiropoulos PG; Arsenian-Henriksson M; Stahle M; Pivarcsi A
• Article: ACTA PAEDIATRICA. 2012;101(3):313-318

  Risk factors for early death in children with haemophagocytic lymphohistiocytosis

  Trottestam H; Berglof E; Horne A; Onelov E; Beutel K; Lehmberg K; Sieni E; Silfverberg T; Arico M; Janka G; Henter J-I
• Article: JOURNAL OF IMMUNOLOGY. 2012;188(5):2218-2226

  Skewing of the NK Cell Repertoire by MHC Class I via Quantitatively Controlled Enrichment and Contraction of Specific Ly49 Subsets

  Brodin P; Lakshmikanth T; Karre K; Hoglund P
• Article: BMJ OPEN. 2012;2(4):e001152

  Cause-specific infant mortality in a population-based Swedish study of term and post-term births: the contribution of gestational age and birth weight

  Altman M; Bonamy A-KE; Wikstrom A-K; Cnattingius S
• Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2012;67(1):32-38

  A non-infectious cell-based phenotypic assay for the assessment of HIV-1 susceptibility to protease inhibitors.

  Buzon MJ; Erkizia I; Pou C; Minuesa G; Puertas MC; Esteve A; Castello A; Santos JR; Prado JG; Izquierdo-Useros N; Pattery T; Van Houtte M; Carrasco L; Clotet B; Ruiz L; Martinez-Picado J
• Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2012;158(3):299-306

  Challenge of Isolated Sputum Cells Supports in vivo Origin of Intolerance Reaction to Aspirin/Non-Steroidal Anti-Inflammatory Drugs in Asthma

  Higashi A; Kumlin M; Higashi N; Daham K; Gaber F; Lindeberg A; James A; Skedinger M; Delin I; Gyllfors P; Dahlen S-E; Dahlen B
• Article: PLOS ONE. 2012;7(2):e32714

  In-depth characterization of viral isolates from plasma and cells compared with plasma circulating quasispecies in early HIV-1 infection.

  Dalmau J; Codoñer FM; Erkizia I; Pino M; Pou C; Paredes R; Clotet B; Martinez-Picado J; Prado JG
• Doctoral thesis: 2011

  MHC class I molecules in natural killer cell education and tolerance

  Brodin, Petter
• Article: BLOOD. 2011;118(17):4577-4584

  Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol

  Trottestam H; Horne A; Arico M; Egeler RM; Filipovich AH; Gadner H; Imashuku S; Ladisch S; Webb D; Janka G; Henter J-I
• Article: CELL CYCLE. 2011;10(19):3346-3358

  Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2

  Li H; Lakshmikanth T; Garofalo C; Enge M; Spinnler C; Anichini A; Szekely L; Karre K; Carbone E; Selivanova G
• Article: PLOS PATHOGENS. 2011;7(10):e1002314

  Deep molecular characterization of HIV-1 dynamics under suppressive HAART.

  Buzón MJ; Codoñer FM; Frost SDW; Pou C; Puertas MC; Massanella M; Dalmau J; Llibre JM; Stevenson M; Blanco J; Clotet B; Paredes R; Martinez-Picado J
• Article: JOURNAL OF INFECTIOUS DISEASES. 2011;204(5):741-752

  A376S in the connection subdomain of HIV-1 reverse transcriptase confers increased risk of virological failure to nevirapine therapy.

  Paredes R; Puertas MC; Bannister W; Kisic M; Cozzi-Lepri A; Pou C; Bellido R; Betancor G; Bogner J; Gargalianos P; Bánhegyi D; Clotet B; Lundgren J; Menéndez-Arias L; Martinez-Picado J; EuroSIDA Study Group
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2011;131(7):1521-1529

  MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2

  Xu N; Brodin P; Wei T; Meisgen F; Eidsmo L; Nagy N; Kemeny L; Stahle M; Sonkoly E; Pivarcsi A
• Doctoral thesis: 2011

  Moderately preterm infants : studies on length of hospital stay and neonatal outcome

  Altman, Maria
• Article: JOURNAL OF PEDIATRICS. 2011;158(2):239-44.e1

  Neonatal Morbidity in Moderately Preterm Infants: A Swedish National Population-Based Study

  Altman M; Vanpee M; Cnattingius S; Norman M
• Article: PLOS ONE. 2011;6(5):e19461

  Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects.

  Codoñer FM; Pou C; Thielen A; García F; Delgado R; Dalmau D; Álvarez-Tejado M; Ruiz L; Clotet B; Paredes R
• Article: ANTIVIRAL RESEARCH. 2010;88(3):281-286

  Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure.

  Codoñer FM; Pou C; Thielen A; García F; Delgado R; Dalmau D; Santos JR; Buzón MJ; Martínez-Picado J; Alvarez-Tejado M; Clotet B; Ruiz L; Paredes R
• Article: PLOS ONE. 2010;5(10):e13174

  Natural Killer Cell Tolerance Persists Despite Significant Reduction of Self MHC Class I on Normal Target Cells in Mice

  Brodin P; Lakshmikanth T; Mehr R; Johansson MH; Duru AD; Achour A; Salmon-Divon M; Karre K; Hoglund P; Johansson S
• Review: NATURE REVIEWS IMMUNOLOGY. 2010;10(10):724-734

  Current perspectives of natural killer cell education by MHC class I molecules

  Hoeglund P; Brodin P
• Review: TRENDS IN IMMUNOLOGY. 2010;31(9):339-345

  New views on natural killer cell-based immunotherapy for melanoma treatment

  Burke S; Lakshmikanth T; Colucci F; Carbone E
• Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2010;40(3):813-823

  In vivo tumor cell rejection induced by NK cell inhibitory receptor blockade: Maintained tolerance to normal cells even in the presence of IL-2

  Vahlne G; Lindholm K; Meier A; Wickstrom S; Lakshmikanth T; Brennan F; Wilken M; Nielsen R; Romagne F; Wagtmann NR; Karre K; Johansson MH
• Article: JOURNAL OF BIOMEDICAL OPTICS. 2010;15(2):027007

  Monitoring human leukocyte antigen class I molecules by micro-Raman spectroscopy at single-cell level

  Das G; La Rocca R; Lakshmikanth T; Gentile F; Tallerico R; Zambetti LP; Devitt J; Candeloro P; De Angelis F; Carbone E; Di Fabrizio E
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(4):1553-1558

  MYCN-regulated microRNAs repress estrogen receptor-α (ESR1) expression and neuronal differentiation in human neuroblastoma

  Loven J; Zinin N; Wahlstrom T; Muller I; Brodin P; Fredlund E; Ribacke U; Pivarcsi A; Pahlman S; Henriksson M
• Article: ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION. 2009;94(6):F414-F418

  Moderately preterm infants and determinants of length of hospital stay

  Altman M; Vanpee M; Cnattingius S; Norman M
• Article: JOURNAL OF NEUROSCIENCE. 2009;29(43):13503-13515

  Classical Major Histocompatibility Complex Class I Molecules in Motoneurons: New Actors at the Neuromuscular Junction

  Thams S; Brodin P; Plantman S; Saxelin R; Karre K; Cullheim S
• Article: PLOS ONE. 2009;4(6):e6046

  Probing Natural Killer Cell Education by Ly49 Receptor Expression Analysis and Computational Modelling in Single MHC Class I Mice

  Johansson S; Salmon-Divon M; Johansson MH; Pickman Y; Brodin P; Karre K; Mehr R; Hoglund P
• Doctoral thesis: 2009

  Clinical and epidemiological studies of haemophagocytic lymphohistiocytosis

  Horne, AnnaCarin
• Article: JOURNAL OF CLINICAL INVESTIGATION. 2009;119(5):1251-1263

  NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

  Lakshmikanth T; Burke S; Ali TH; Kimpfler S; Ursini F; Ruggeri L; Capanni M; Umansky V; Paschen A; Sucker A; Pende D; Groh V; Biassoni R; Hoglund P; Kato M; Shibuya K; Schadendorf D; Anichini A; Ferrone S; Velardi A; Karre K; Shibuya A; Carbone E; Colucci F
• Article: JOURNAL OF IMMUNOLOGY. 2009;182(8):4529-4537

  Early Hematopoietic Zinc Finger Protein Prevents Tumor Cell Recognition by Natural Killer Cells

  La Rocca R; Fulciniti M; Lakshmikanth T; Mesuraca M; Ali TH; Mazzei V; Amodio N; Catalano L; Rotoli B; Ouerfelli O; Grieco M; Gulletta E; Bond HM; Morrone G; Ferrone S; Carbone E
• Review: TRENDS IN IMMUNOLOGY. 2009;30(4):143-149

  NK cell education: not an on-off switch but a tunable rheostat

  Brodin P; Karre K; Hoglund P
• Article: IMMUNITY. 2009;30(3):337-347

  A Role for cis Interaction between the Inhibitory Ly49A Receptor and MHIC Class I for Natural Killer Cell Education

  Chalifour A; Scarpellino L; Back J; Brodin P; Devevre E; Gros F; Levy F; Leclercq G; Hoglund P; Beermann F; Held W
• Article: BLOOD. 2009;113(11):2434-2441

  The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells

  Brodin P; Lakshmikanth T; Johansson S; Karre K; Hoglund P
• Article: JOURNAL OF MEDICAL GENETICS. 2009;46(3):159-167

  The protective effect of farm animal exposure on childhood allergy is modified by NPSR1 polymorphisms

  Bruce S; Nyberg F; Melen E; James A; Pulkkinen V; Orsmark-Pietras C; Bergstrom A; Dahlen B; Wickman M; von Mutius E; Doekes G; Lauener R; Riedler J; Eder W; van Hage M; Pershagen G; Scheynius A; Kere J
• Article: JOURNAL OF IMMUNOLOGY. 2009;182(3):1460-1468

  Distinct and Overlapping Patterns of Cytokine Regulation of Thymic and Bone Marrow-Derived NK Cell Development

  Cheng M; Charoudeh HN; Brodin P; Tang Y; Lakshmikanth T; Hoglund P; Jacobsen SEW; Sitnicka E
• Article: THORAX. 2008;63(12):1076-1082

  Increased levels of cysteinyl-leukotrienes in saliva, induced sputum, urine and blood from patients with aspirin-intolerant asthma

  Gaber F; Daham K; Higashi A; Higashi N; Gulich A; Delin I; James A; Skedinger M; Gyllfors P; Nord M; Dahlen S-E; Kumlin M; Dahlen B
• Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(11):2934-2937

  Beyond licensing and disarming: A quantitative view on NK-cell education

  Brodin P; Hoglund P
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;143(1):75-83

  Characterization of PRF1, STX11 and UNC13D genotype-phenotype correlations in familial hemophagocytic lymphohistiocytosis

  Horne A; Ramme KG; Rudd E; Zheng C; Wali Y; al-Lamki Z; Guergey A; Yalman N; Nordenskjold M; Henter J-I
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;140(3):327-335

  Frequency and spectrum of central nervous system involvement in 193 children with haemophagocytic lymphohistiocytosis

  Horne A; Trottestam H; Arico M; Egeler RM; Filipovich AH; Gadner H; Imashuku S; Ladisch S; Webb D; Janka G; Henter J-I
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(1):1-11

  IFN-γ production and degranulation are differentially regulated in response to stimulation in murine natural killer cells

  Vahlne G; Becker S; Brodin P; Johansson MH
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(1):30-36

  Critical role of Qa1^b in the protection of mature dendritic cells from NK cell-mediated killing

  Persson CM; Assarsson E; Vahlne G; Brodin P; Chambers BJ
• Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;119(5):1267-1268

  Assessment of in vivo 5-lipoxygenase activity by analysis of leukotriene B₄ in saliva:: Effects of treatment with zileuton

  Gaber F; James A; Delin I; Wetterholm A; Sampson AP; Dahlen B; Dahlen S-E; Kumlin M
• Published conference paper: MICROELECTRONIC ENGINEERING. 2007;84(5-8):1729-1732

  Preliminary study of micromechanical stress delivery for cell biology studies

  Matteucci M; Lakshmikanth T; Shibu K; De Angelis F; Schadendorf D; Venuta S; Carbone E; Di Fabrizio E
• Review: PEDIATRIC BLOOD & CANCER. 2007;48(2):124-131

  HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis

  Henter J-I; Horne A; Arico M; Egeler RM; Filipovich AH; Imashuku S; Ladisch S; McClain K; Webb D; Winiarski J; Janka G
• Article: ACTA PAEDIATRICA. 2006;95(10):1228-1233

  Shorter hospital stay for moderately preterm infants

  Altman M; Vanpee M; Bendito A; Norman M
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2005;129(5):658-666

  Subtyping of natural killer cell cytotoxicity deficiencies in haemophagocytic lymphohistocytosis provides therapeutic guidance

  Horne A; Zheng CY; Lorenz I; Löfstedt M; Montgomery SM; Janka G; Henter JI; Schneider EM
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2005;129(5):622-630

  Haematopoietic stem cell transplantation in haemophagocytic lymphohistiocytosis

  Horne A; Janka G; Egeler RM; Gadner H; Imashuku S; Ladisch S; Locatelli F; Montgomery SM; Webb D; Winiarski J; Filipovich AH; Henter JI
• Article: NATIONAL ACADEMY SCIENCE LETTERS-INDIA. 2005;28(9-10):353-355

  Detection of haemocyanin in native PAGE gels

  Krupanidhi S; Lakshmikanth T
• Article: BLOOD. 2002;100(7):2367-2373

  Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation

  Henter JI; Samuelsson-Horne A; Aricò M; Egeler RM; Elinder G; Filipovich AH; Gadner H; Imashuku S; Komp D; Ladisch S; Webb D; Janka G
• Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2001;68(3):590-597

  Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis

  Ericson KG; Fadeel B; Nilsson-Ardnor S; Söderhäll C; Samuelsson A; Janka G; Schneider M; Gürgey A; Yalman N; Révész T; Egeler RM; Jahnukainen K; Storm-Mathiesen I; Haraldsson A; Poole J; de Saint Basile G; Nordenskjöld M; Henter JI
• Review: LAKARTIDNINGEN. 2000;97(12):1405-1408

  [Familial hemophagocytic lymphohistiocytosis: diagnosis, treatment and pathophysiological mechanisms].

  Henter JI; Samuelsson A; Ericson K; Nilsson-Ardnor S; Elinder G; Fadeel B
• Visa fler

Medarbetare och kontakt

Gruppledare

• 

  Petter Brodin

  Professor/Specialistläkare | Docent

  Telefon +46852481396

  E-postadress petter.brodin@ki.se

Alla medarbetare i gruppen

• 

  Maria Altman

  Anknuten till Forskning | Docent

  E-postadress maria.altman@ki.se
• Aron Arzoomand

  Doktorand

  E-postadress aron.arzoomand@ki.se
• Hugo Barcenilla

  Forskningsspecialist

  E-postadress hugo.barcenilla@ki.se
• Anna Karin Bernhardsson

  Forskningssköterska

  E-postadress anna.karin.bernhardsson@ki.se
• 

  Petter Brodin

  Professor/Specialistläkare | Docent

  Telefon +46852481396

  E-postadress petter.brodin@ki.se
• Alexis Chasseur

  Postdoktor

  E-postadress alexis.chasseur@ki.se
• Qi Chen

  Assistent Klinisk

  E-postadress qi.chen.2@ki.se
• 

  Yang Chen

  Senior Forskningsspecialist

  E-postadress yang.chen@ki.se
• Rikard Forlin

  Doktorand | Assistent Klinisk

  E-postadress rikard.forlin@ki.se
• Laura Gonzalez

  Laboratorietekniker

  E-postadress laura.gonzalez@ki.se
• Annacarin Horne

  Anknuten till Forskning

  E-postadress annacarin.horne@ki.se
• Rita Ivanchenko

  Postdoktor

  E-postadress rita.ivanchenko@ki.se
• Anna James

  Forskare

  Telefon +46852487514

  E-postadress anna.james@ki.se
• Anette Johnsson

  Laboratorietekniker

  E-postadress anette.johnsson@ki.se
• Genia Kretzschmar

  Doktorand

  E-postadress genia.kretzschmar@ki.se
• Florens Lohrmann

  Postdoktorala Studier

  E-postadress florens.lohrmann@ki.se
• 

  Jaromir Mikes

  Senior Forskningsspecialist

  Telefon +46852486945

  E-postadress jaromir.mikes@ki.se
• Erika Negrini

  Laboratorietekniker

  E-postadress erika.negrini@ki.se
• 

  Stefan Reitzner

  Biträdande Lektor

  E-postadress stefan.reitzner@ki.se
• Lucie Rodriguez

  Anknuten till Forskning

  E-postadress lucie.rodriguez@ki.se
• 

  Meng Sun

  Forskningsspecialist

  E-postadress meng.sun@ki.se
• 

  Lakshmikanth Tadepally

  Senior Forskningsspecialist

  Telefon +46852481231

  E-postadress lakshmikanth.tadepally@ki.se
• Ziyang Tan

  Postdoktor

  E-postadress ziyang.tan@ki.se
• Joël Tekoniemi

  Laboratorietekniker

  E-postadress joel.tekoniemi@ki.se
• Jun Wang

  Senior Forskningsinfrastrukturspecialist

  E-postadress jun.wang@ki.se
• 

  Binbin Zhao

  Doktorand

  E-postadress binbin.zhao@ki.se
• Baohui Zhu

  Postdoktor

  E-postadress baohui.zhu@ki.se

Pediatric Systems Immunology

Petter Brodin

Professor/Specialistläkare

Telefon: +46852481396

E-post: petter.brodin@ki.se

Så dramatiskt utvecklas vårt immunförsvar efter födseln

Foto: Ulf Sirborn

Så dramatiskt utvecklas vårt immunförsvar efter födseln

När ett barn lämnar mammans mage startar en dramatisk förändring av barnets immunförsvar. Förändringen är en respons på de bakterier, virus och liknande som finns i barnets nya miljö, och sker likartat hos alla barn. Resultaten publiceras av forskare från Karolinska Institutet i en artikel i Cell. Användningen av ny teknik inom immuncellsanalys har gjort studien möjlig.

Skyddande antikroppar finns även hos för tidigt födda

Foto: Ulf Sirborn

Skyddande antikroppar finns även hos för tidigt födda

Även mycket för tidigt födda barn bär på ett skydd mot virus i form av antikroppar överförda från mamman. Det visar en analys av så kallade maternella antikroppar hos nyfödda barn, publicerad i tidskriften Nature Medicine av forskare vid Karolinska Institutet. Resultaten bör förändra vårt sätt att se på infektionskänslighet hos nyfödda, enligt forskarna

Lakshmikanth Tadepally

Ph.D. Immunologist. Head of Facility, National Mass cytometry Facility

Telefon: +46852481231

E-post: lakshmikanth.tadepally@ki.se

Yang Chen

Ph.D. Senior Data scientist

E-post: yang.chen@ki.se

Jaromir Mikes

Ph.D. Head of FACS facility

Telefon: +46852486945

E-post: jaromir.mikes@ki.se