Pediatric Systems Immunology – Petter Brodin's research group

Publications

All publications from group members

• Journal article: JOURNAL OF IMMUNOLOGY. 2024;213(10):1452-1466

  NK Cell and Monocyte Dysfunction in Multisystem Inflammatory Syndrome in Children

  Dick JK; Sangala JA; Krishna VD; Khaimraj A; Hamel L; Erickson SM; Hicks D; Soigner Y; Covill LE; Johnson AK; Ehrhardt MJ; Ernste K; Brodin P; Koup RA; Khaitan A; Baehr C; Thielen BK; Henzler CM; Skipper C; Miller JS; Bryceson YT; Wu J; John CC; Panoskaltsis-Mortari A; Orioles A; Steiner ME; Cheeran MCJ; Pravetoni M; Hart GT
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: IN PRACTICE. 2024;12(11):2996-3013.e7

  Interleukin (IL)-1/IL-6-Inhibitor-Associated Drug Reaction With Eosinophilia and Systemic Symptoms (DReSS) in Systemic Inflammatory Illnesses.

  Saper VE; Tian L; Verstegen RHJ; Conrad CK; Cidon M; Hopper RK; Kuo CS; Osoegawa K; Baszis K; Bingham CA; Ferguson I; Hahn T; Horne A; Isupova EA; Jones JT; Kasapcopur Ö; Klein-Gitelman MS; Kostik MM; Ozen S; Phadke O; Prahalad S; Randell RL; Sener S; Stingl C; Abdul-Aziz R; Akoghlanian S; Al Julandani D; Alvarez MB; Bader-Meunier B; Balay-Dustrude EE; Balboni I; Baxter SK; Berard RA; Bhattad S; Bolaria R; Boneparth A; Cassidy EA; Co DO; Collins KP; Dancey P; Dickinson AM; Edelheit BS; Espada G; Flanagan ER; Imundo LF; Jindal AK; Kim H-A; Klaus G; Lake C; Lapin WB; Lawson EF; Marmor I; Mombourquette J; Ogunjimi B; Olveda R; Ombrello MJ; Onel K; Poholek C; Ramanan AV; Ravelli A; Reinhardt A; Robinson AD; Rouster-Stevens K; Saad N; Schneider R; Selmanovic V; Sefic Pasic I; Shenoi S; Shilo NR; Soep JB; Sura A; Taber SF; Tesher M; Tibaldi J; Torok KS; Tsin CM; Vasquez-Canizares N; Villacis Nunez DS; Way EE; Whitehead B; Zemel LS; Sharma S; Fernández-Viña MA; Mellins ED; CARRA Registry Investigators
• Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2024;45(1):31

  Normalized Interferon Signatures and Clinical Improvements by IFNAR1 Blocking Antibody (Anifrolumab) in Patients with Type I Interferonopathies

  Kretzschmar G; Paez LP; Tan Z; Wang J; Gonzalez L; Mugabo CH; Johnsson A; Chen Y; Mikes J; Lakshmikanth T; James A; Goldbach-Mansky R; Fischer M; Palmblad K; Alehashemi S; Horne A; Brodin P
• Article: SCIENTIFIC REPORTS. 2024;14(1):24512

  Autoantibodies to protein S may explain rare cases of coagulopathy following COVID-19 vaccination

  Yalcinkaya A; Cavalli M; Aranda-Guillen M; Cederholm A; Guner A; Rietrae I; Mildner H; Behere A; Eriksson O; Gonzalez L; Mugabo CH; Johnsson A; Lakshmikanth T; Brodin P; Wadelius M; Hallberg P; Landegren N
• Journal article: JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY. 2024;13(Supplement_4):8-9

  Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C)

  Dick JK; Sangala JA; Krishna VD; Khaimraj A; Hamel L; Erickson SM; Hicks D; Soigner Y; Covill LE; Johnson AK; Ehrhardt MJ; Ernste K; Brodin P; Koup RA; Khaitan A; Baehr C; Thielen BK; Henzler CM; Skipper C; Miller JS; Bryceson YT; Wu J; John CC; Panoskaltsis-Mortari A; Orioles A; Steiner ME; Cheeran MC-J; Pravetoni M; Hart GT
• Corrigendum: NATURE. 2024;634(8033):E5

  Immune system adaptation during gender-affirming testosterone treatment (vol 633, pg 155, 2024)

  Lakshmikanth T; Consiglio C; Sardh F; Forlin R; Wang J; Tan Z; Barcenilla H; Rodriguez L; Sugrue J; Noori P; Ivanchenko M; Paez LP; Gonzalez L; Mugabo CH; Johnsson A; Ryberg H; Hallgren A; Pou C; Chen Y; Mikes J; James A; Dahlqvist P; Wahlberg J; Hagelin A; Holmberg M; Degerblad M; Isaksson M; Duffy D; Kampe O; Landegren N; Brodin P
• Journal article: NATURE REVIEWS IMMUNOLOGY. 2024;24(10):697-698

  Immunological studies in trans-individuals undergoing gender affirming hormone therapy

  James A; Brodin P
• Journal article: NATURE REVIEWS IMMUNOLOGY. 2024;24(10):771

  Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy.

  James A; Brodin P
• Article: PEDIATRIC INFECTIOUS DISEASE JOURNAL. 2024

  Cytokine Profile in Children Following SARS-CoV-2 Infection: Preliminary Findings.

  Buonsenso D; Camporesi A; Di Sante G; Sali M; Boza MDCP; Morello R; Valentini P; Raffaelli F; Rodriguez L; Gonzalez L; Johnsson A; Mugabo CH; Lakshmikanth T; Brodin P
• Article: NATURE. 2024;633(8028):155-164

  Immune system adaptation during gender-affirming testosterone treatment

  Lakshmikanth T; Consiglio C; Sardh F; Forlin R; Wang J; Tan Z; Barcenilla H; Rodriguez L; Sugrue J; Noori P; Ivanchenko M; Paez LP; Gonzalez L; Mugabo CH; Johnsson A; Ryberg H; Hallgren A; Pou C; Chen Y; Mikes J; James A; Dahlqvist P; Wahlberg J; Hagelin A; Holmberg M; Degerblad M; Isaksson M; Duffy D; Kampe O; Landegren N; Brodin P
• Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2024;221(9):e20231725

  SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency

  Chan Y-H; Lundberg V; Le Pen J; Yuan J; Lee D; Pinci F; Volpi S; Nakajima K; Bondet V; Akesson S; Khobrekar NV; Bodansky A; Du L; Melander T; Mariaggi A-A; Seeleuthner Y; Saleh TS; Chakravarty D; Marits P; Dobbs K; Vonlanthen S; Hennings V; Thorn K; Rinchai D; Bizien L; Chaldebas M; Sobh A; Ozcelik T; Keles S; AlKhater SA; Prando C; Meyts I; Wilson MR; Rosain J; Jouanguy E; Aubart M; Abel L; Mogensen TH; Pan-Hammarstrom Q; Gao D; Duffy D; Cobat A; Berg S; Notarangelo LD; Harschnitz O; Rice CM; Studer L; Casanova J-L; Ekwall O; Zhang S-Y
• Article: RHEUMATOLOGY. 2024;63(SI2):si122-si128

  Comparison of EULAR/PRINTO/PReS Ankara 2008 and 2022 ACR/EULAR classification criteria for granulomatosis with polyangiitis in children.

  Kaya Akca U; Batu ED; Jelusic M; Calatroni M; Bakry R; Frkovic M; Vinšová N; Campos RT; Horne A; Caglayan S; Vaglio A; Moroni G; Emmi G; Ghiggeri GM; Koker O; Sinico RA; Kim S; Gagro A; Matucci-Cerinic C; Çomak E; Ekici Tekin Z; Arslanoglu Aydin E; Heshin-Bekenstein M; Acar BC; Gattorno M; Akman S; Sozeri B; Palmblad K; Al-Mayouf SM; Silva CA; Doležalová P; Merkel PA; Ozen S
• Article: JOURNAL OF PHYSIOLOGY. 2024;602(17):4171-4193

  Muscle memory in humans: evidence for myonuclear permanence and long-term transcriptional regulation after strength training

  Cumming KT; Reitzner SM; Hanslien M; Skilnand K; Seynnes OR; Horwath O; Psilander N; Sundberg CJ; Raastad T
• Article: BLOOD. 2024;144(8):873-887

  Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis.

  Chiang SCC; Covill LE; Tesi B; Campbell TM; Schlums H; Nejati-Zendegani J; Mördrup K; Wood S; Theorell J; Sekine T; Al-Herz W; Akar HH; Belen FB; Chan MY; Devecioglu O; Aksu T; Ifversen M; Malinowska I; Sabel M; Unal E; Unal S; Introne WJ; Krzewski K; Gilmour KC; Ehl S; Ljunggren H-G; Nordenskjöld M; Horne A; Henter J-I; Meeths M; Bryceson YT
• Thesis / dissertation: 2024

  Multiomic analysis of T cells in response to cancers and microbes

  Tan, Ziyang
• Review: RHEUMATOLOGY. 2024;:keae391

  Current treatment in macrophage activation syndrome worldwide: a systematic literature review to inform the METAPHOR project

  Baldo F; Erkens RGA; Mizuta M; Rogani G; Lucioni F; Bracaglia C; Foell D; Gattorno M; Jelusic M; Anton J; Brogan P; Canna S; Chandrakasan S; Cron RQ; De Benedetti F; Grom A; Heshin-Bekenstein M; Horne A; Khubchandani R; Ozen S; Quartier P; Ravelli A; Shimizu M; Schulert G; Scott C; Sinha R; Ruperto N; Swart JF; Vastert S; Minoia F
• Article: BLOOD. 2024;:2308-2318

  Diagnostic Guidelines for Familial Hemophagocytic Lymphohistiocytosis Revisited.

  Henter J-I; Sieni E; Eriksson J; Bergsten E; Hed Myrberg I; Canna S; Coniglio ML; Cron RQ; Kernan KF; Kumar AR; Lehmberg K; Minoia F; Naqvi A; Ravelli A; Tang Y; Bottai M; Bryceson YT; Horne A; Jordan MB
• Journal article: BMC MEDICINE. 2024;22(1):295

  Foetal gluten immunogenic peptides during pregnancy: a new determinant on the coeliac exposome

  Moreno MDL; Gonzalez-Rovira M; Martinez-Pancorbo C; Martin-Camean M; Najar-Moyano AM; Romero M; de la Hoz E; Lopez-Beltran C; Mellado E; Bartha JL; Brodin P; Rodriguez-Herrera A; Sainz-Bueno JA; Sousa C
• Article: BMC BIOLOGY. 2024;22(1):147

  DNA methylation of exercise-responsive genes differs between trained and untrained men

  Geiger C; Needhamsen M; Emanuelsson EB; Norrbom J; Steindorf K; Sundberg CJ; Reitzner SM; Lindholm ME
• Article: PHYSIOLOGICAL REPORTS. 2024;12(14):e16161

  Levels of circulating angiotensin-converting enzyme 2 are affected by acute exercise and correlate with markers of physical fitness in male athletes

  Reitzner SM; Emanuelsson EB; Sundberg CJ
• Article: DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY. 2024;66(7):902-909

  Circulating immune cell populations at rest and in response to acute endurance exercise in young adults with cerebral palsy

  Kruse A; Imery I; Corell L; Hjalmarsson E; Fernandez-Gonzalo R; Von Walden F; Reitzner SM
• Article: NATURE METHODS. 2024;21(6):1044-1052

  Molecular pixelation: spatial proteomics of single cells by sequencing

  Karlsson F; Kallas T; Thiagarajan D; Karlsson M; Schweitzer M; Navarro JF; Leijonancker L; Geny S; Pettersson E; Rhomberg-Kauert J; Larsson L; van Ooijen H; Petkov S; Gonzalez-Granillo M; Bunz J; Dahlberg J; Simonetti M; Sathe P; Brodin P; Barrio AM; Fredriksson S
• Conference publication: PHYSIOLOGY. 2024;39(S1):646

  Remodeling of the Human Skeletal Muscle Proteome Found After Long-Term Endurance Training but Not After Strength Training

  Emanuelsson E; Arif M; Reitzner S; Perez S; Lindholm M; Mardinoglu A; Daub C; Sundberg CJ; Chapman M
• Article: ACTA PHYSIOLOGICA. 2024;240(5):e14129

  The effect of neuromuscular electrical stimulation on the human skeletal muscle transcriptome.

  Flodin J; Reitzner SM; Emanuelsson EB; Sundberg CJ; Ackermann P
• Journal article: BIORXIV. 2024;:2024.04.16.589585

  Antibody-mediated cellular responses are dysregulated in Multisystem Inflammatory Syndrome in Children (MIS-C).

  Dick JK; Sangala JA; Krishna VD; Khaimraj A; Hamel L; Erickson SM; Hicks D; Soigner Y; Covill LE; Johnson A; Ehrhardt MJ; Ernste K; Brodin P; Koup RA; Khaitan A; Baehr C; Thielen BK; Henzler CM; Skipper C; Miller JS; Bryceson YT; Wu J; John CC; Panoskaltsis-Mortari A; Orioles A; Steiner ME; Cheeran MC-J; Pravetoni M; Hart GT
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2024;99(4):e13346

  Gut bacteria at 6 months of age are associated with immune cell status in 1-year-old children

  Nilsen M; Nygaard UC; Brodin P; Carlsen KCL; Fredheim C; Haugen G; Hedlin G; Jonassen CM; Jonsmoen ULA; Lakshmikanth T; Nordlund B; Olin A; Rehbinder EM; Skjerven HO; Snipen L; Staff AC; Soederhaell C; Vettukattil R; Rudi K
• Journal article: CANCER RESEARCH. 2024;84(6):6378

  Systems-level immunomonitoring in children with solid tumors

  Chen Q; Zhao B; Tan Z; Hedberg G; Wang J; Gonzalez L; Mugabo C; Johnsson A; Paez L; Rodriguez L; James A; Chen Y; Mikes J; Barcenilla H; Wang C; Davis MM; Carlson L-M; Pal N; Herold N; Blomgren K; Repsilber D; Lakshmikanth T; Kogner P; Ljungblad L; Brodin P
• Preprint: BIORXIV. 2024

  Cluster-free annotation of single cells using Earth mover’s distance-based classification

  Forlin R; Tajvar P; Wang N; Dimarogonas D; Brodin P
• Preprint: RESEARCH SQUARE. 2024

  Fetal-maternal interactions with gluten immunogenic peptides during pregnancy: a new determinant on the coeliac exposome

  Moreno MDL; González-Rovira M; Martínez-Pancorbo C; Martín-Cameán M; Nájar-Moyano AM; Romero M; Hoz E; López-Beltrán C; Mellado E; Bartha JL; Brodin P; Rodríguez-Herrera A; Sainz-Bueno JL; Sousa C
• Editorial comment: TRENDS IN MOLECULAR MEDICINE. 2024;30(3):200-201

  Immune system perturbations in patients with long COVID

  Rodriguez L; Brodin P
• Article: NATURE. 2024;626(8000):827-835

  Smoking changes adaptive immunity with persistent effects

  Saint-Andre V; Charbit B; Biton A; Rouilly V; Posseme C; Bertrand A; Rotival M; Bergstedt J; Patin E; Albert ML; Quintana-Murci L; Duffy D
• Article: NPJ VACCINES. 2024;9(1):42

  No link between type I interferon autoantibody positivity and adverse reactions to COVID-19 vaccines

  Yalcinkaya A; Cavalli M; Cederholm A; Aranda-Guillen M; Behere A; Mildner H; Lakshmikanth T; Gonzalez L; Mugabo CH; Johnsson A; Ekwall O; Kampe O; Bensing S; Brodin P; Hallberg P; Wadelius M; Landegren N
• Preprint: MEDRXIV. 2024

  Restrained memory CD8⁺T cell responses favors viral persistence and elevated IgG responses in patients with severe Long COVID

  Rodriguez L; Tan Z; Lakshmikanth T; Wang J; Barcenilla H; Swank Z; Zuo F; Abolhassani H; Pavlovitch-Bedzyk AJ; Wang C; Gonzalez L; Mugabo CH; Johnsson A; Chen Y; James A; Mikes J; Kleberg L; Sundling C; Björnson M; Bonnier MN; Ståhlberg M; Runold M; Björkander S; Melén E; Meyts I; Weyenbergh JV; Hammarström Q-P; Davis M; Walt D; Landegren N; COVID Human Genetic Effort; Aiuti A; Casari G; Casanova J-L; Jamoulle M; Bruchfeld J; Brodin P
• Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2024;221(2):e20231353

  Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children

  Bastard P; Gervais A; Taniguchi M; Saare L; Sarekannu K; Le Voyer T; Philippot Q; Rosain J; Bizien L; Asano T; Garcia-Prat M; Parra-Martinez A; Migaud M; Tsumura M; Conti F; Belot A; Riviere JG; Morio T; Tanaka J; Javouhey E; Haerynck F; Duvlis S; Ozcelik T; Keles S; Tandjaoui-Lambiotte Y; Escoda S; Husain M; Pan-Hammarstrom Q; Hammarstrom L; Ahlijah G; Haidar AA; Soudee C; Arseguel V; Abolhassani H; Sahanic S; Tancevski I; Nukui Y; Hayakawa S; Chrousos GP; Michos A; Tatsi E-B; Filippatos F; Rodriguez-Palmero A; Troya J; Tipu I; Meyts I; Roussel L; Ostrowski SR; Schidlowski L; Prando C; Condino-Neto A; Cheikh N; Bousfiha AA; El Bakkouri J; Peterson P; Pujol A; Levy R; Quartier P; Vinh DC; Boisson B; Beziat V; Zhang S-Y; Borghesi A; Pession A; Andreakos E; Marr N; Mentis A-FA; Mogensen TH; Rodriguez-Gallego C; Soler-Palacin P; Colobran R; Tillmann V; Neven B; Trouillet-Assant S; Brodin P; Abel L; Jouanguy E; Zhang Q; Martinon-Torres F; Salas A; Gomez-Carballa A; Gonzalez-Granado LI; Kisand K; Okada S; Puel A; Cobat A; Casanova J-L
• Article: PEDIATRIC RESEARCH. 2024;95(3):762-769

  Antisecretory factor in breastmilk is associated with reduced incidence of sepsis in preterm infants

  Gustafsson A; Johansson E; Henckel E; Olin A; Rodriguez L; Brodin P; Lange S; Bohlin K
• Article: CYTOMETRY. PART A : THE JOURNAL OF THE INTERNATIONAL SOCIETY FOR ANALYTICAL CYTOLOGY. 2024;105(2):124-138

  Standardized high-dimensional spectral cytometry protocol and panels for whole blood immune phenotyping in clinical and translational studies.

  Dott T; Culina S; Chemali R; Mansour CA; Dubois F; Jagla B; Doisne JM; Rogge L; Huetz F; Jönsson F; Commere P-H; Di Santo J; Terrier B; Quintana-Murci L; Duffy D; Hasan M; Milieu Intérieur Consortium
• Conference publication: 2024;:a1.1-a1a1

  1 The effect of neuromuscular electrical stimulation on human skeletal muscle

  Flodin J; Reitzner S; Emanuelsson E; Sundberg C-J; Ackermann P
• Article: SCIENCE. 2024;383(6680):eadg7942

  Persistent complement dysregulation with signs of thromboinflammation in active Long Covid

  Cervia-Hasler C; Brueningk SC; Hoch T; Fan B; Muzio G; Thompson RC; Ceglarek L; Meledin R; Westermann P; Emmenegger M; Taeschler P; Zurbuchen Y; Pons M; Menges D; Ballouz T; Cervia-Hasler S; Adamo S; Merad M; Charney AW; Puhan M; Brodin P; Nilsson J; Aguzzi A; Raeber ME; Messner CB; Beckmann ND; Borgwardt K; Boyman O
• Article: ISCIENCE. 2024;27(1):108638

  Remodeling of the human skeletal muscle proteome found after long-term endurance training but not after strength training

  Emanuelsson EB; Arif M; Reitzner SM; Perez S; Lindholm ME; Mardinoglu A; Daub C; Sundberg CJ; Chapman MA
• Preprint: BIORXIV. 2024

  High-throughput analysis of membrane fluidity unveils a hidden dimension in immune cell states

  Andronico L; Jiang Y; Carannante V; Iskrak S; Sandoz P; Mikes J; Klymchenko A; Buggert M; Österborg A; Önfelt B; Brodin P; Sezgin E
• Corrigendum: GENOME MEDICINE. 2024;16(1):6

  Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 (vol 15, 22, 2023)

  Matuozzo D; Talouarn E; Marchal A; Zhang P; Manry J; Seeleuthner Y; Zhang Y; Bolze A; Chaldebas M; Milisavljevic B; Gervais A; Bastard P; Asano T; Bizien L; Barzaghi F; Abolhassani H; Tayoun AA; Aiuti A; Darazam IA; Allende LM; Alonso-Arias R; Arias AA; Aytekin G; Bergman P; Bondesan S; Bryceson YT; Bustos IG; Cabrera-Marante O; Carcel S; Carrera P; Casari G; Chaibi K; Colobran R; Condino-Neto A; Covill LE; Delmonte OM; Zein LE; Flores C; Gregersen PK; Gut M; Haerynck F; Halwani R; Hancerli S; Hammarstroem L; Hatipoglu N; Karbuz A; Keles S; Kyheng C; Leon-Lopez R; Franco JL; Mansouri D; Martinez-Picado J; Akcan OM; Migeotte I; Morange P-E; Morelle G; Martin-Nalda A; Novelli G; Novelli A; Ozcelik T; Palabiyik F; Pan-Hammarstroem Q; de Diego RP; Planas-Serra L; Pleguezuelo DE; Prando C; Pujol A; Reyes LF; Riviere JG; Rodriguez-Gallego C; Rojas J; Rovere-Querini P; Schlueter A; Shahrooei M; Sobh A; Soler-Palacin P; Tandjaoui-Lambiotte Y; Tipu I; Tresoldi C; Troya J; van de Beek D; Zatz M; Zawadzki P; Al-Muhsen SZ; Alosaimi MF; Alsohime FM; Baris-Feldman H; Butte MJ; Constantinescu SN; Cooper MA; Dalgard CL; Fellay J; Heath JR; Lau Y-L; Lifton RP; Maniatis T; Mogensen TH; von Bernuth H; Lermine A; Vidaud M; Boland A; Deleuze J-F; Nussbaum R; Kahn-Kirby A; Mentre F; Tubiana S; Gorochov G; Tubach F; Hausfater P; Meyts I; Zhang S-Y; Puel A; Notarangelo LD; Boisson-Dupuis S; Su HC; Boisson B; Jouanguy E; Casanova J-L; Zhang Q; Abel L; Cobat A
• Article: MOLECULAR METABOLISM. 2024;79:101857

  Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise- A systems biology approach

  Reitzner SM; Emanuelsson EB; Arif M; Kaczkowski B; Kwon ATJ; Mardinoglu A; Arner E; Chapman MA; Sundberg CJ
• Review: NATURE REVIEWS GASTROENTEROLOGY AND HEPATOLOGY. 2024;21(1):35-45

  The maternal gut microbiome in pregnancy: implications for the developing immune system

  Koren O; Konnikova L; Brodin P; Mysorekar IU; Collado MC
• Article: SCIENCE IMMUNOLOGY. 2023;8(90):eabp8966

  Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs

  Bastard P; Vazquez S; Liu J; Laurie MT; Wang CY; Gervais A; Le Voyer T; Bizien L; Zamecnik C; Philippot Q; Rosain J; Catherinot E; Willmore A; Mitchell AM; Bair R; Garcon P; Kenney H; Fekkar A; Salagianni M; Poulakou G; Siouti E; Sahanic S; Tancevski I; Weiss G; Nagl L; Manry J; Duvlis S; Arroyo-Sanchez D; Paz Artal E; Rubio L; Perani C; Bezzi M; Sottini A; Quaresima V; Roussel L; Vinh DC; Felipe Reyes L; Garzaro M; Hatipoglu N; Boutboul D; Tandjaoui-Lambiotte Y; Borghesi A; Aliberti A; Cassaniti I; Venet F; Monneret G; Halwani R; Sharif-Askari NS; Danielson J; Burrel S; Morbieu C; Stepanovskyy Y; Bondarenko A; Volokha A; Boyarchuk O; Gagro A; Neuville M; Neven B; Keles S; Hernu R; Bal A; Novelli A; Novelli G; Saker K; Ailioaie O; Antoli A; Jeziorski E; Rocamora-Blanch G; Teixeira C; Delaunay C; Lhuillier M; Le Turnier P; Zhang Y; Mahevas M; Pan-Hammarstrom Q; Abolhassani H; Bompoil T; Dorgham K; Group FCS; Gorochov G; Laouenan C; Rodriguez-Gallego C; Ng LFP; Renia L; Pujol A; Belot A; Raffi F; Allende LM; Martinez-Picado J; Ozcelik T; Keles S; Imberti L; Notarangelo LD; Troya J; Solanich X; Zhang S-Y; Puel A; Wilson MR; Trouillet-Assants S; Abe L; Jouanguy E; Ye CJ; Cobat A; Thompson LM; Andreakos E; Zhang Q; Anderson MS; Casanova J-L; DeRisi JL
• Article: GUT MICROBES. 2023;15(2):2287618

  Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response.

  Delavy M; Sertour N; Patin E; Le Chatelier E; Cole N; Dubois F; Xie Z; Saint-André V; Manichanh C; Walker AW; Quintana-Murci L; Duffy D; d'Enfert C; Bougnoux M-E; Consortium MI
• Conference publication: 2023;00:715-720

  Modelling Pathogen Response of the Human Immune System in a Reduced State Space

  Tajvar P; Forlin R; Brodin P; Dimarogonas DV
• Article: ADVANCED SCIENCE. 2023;10(35):e2300123

  Identification and Characterization of CD8⁺CD27⁺CXCR3^- T Cell Dysregulation and Progression-Associated Biomarkers in Systemic Lupus Erythematosus

  Zhang L; Du F; Jin Q; Sun L; Wang B; Tan Z; Meng X; Huang B; Zhan Y; Su W; Song R; Wu C; Chen L; Chen X; Ding X
• Article: NATURE. 2023;623(7988):803-813

  Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

  Le Voyer T; Parent AV; Liu X; Cederholm A; Gervais A; Rosain J; Nguyen T; Lorenzo MP; Rackaityte E; Rinchai D; Zhang P; Bizien L; Hancioglu G; Ghillani-Dalbin P; Charuel J-L; Philippot Q; Gueye MS; Renkilaraj MRLM; Ogishi M; Soudee C; Migaud M; Rozenberg F; Momenilandi M; Riller Q; Imberti L; Delmonte OM; Mueller G; Keller B; Orrego J; Gallego WAF; Rubin T; Emiroglu M; Parvaneh N; Eriksson D; Aranda-Guillen M; Berrios DI; Vong L; Katelaris CH; Mustillo P; Raedler J; Bohlen J; Celik JB; Astudillo C; Winter S; McLean C; Guffroy A; DeRisi JL; Yu D; Miller C; Feng Y; Guichard A; Beziat V; Bustamante J; Pan-Hammarstrom Q; Zhang Y; Rosen LB; Holland SM; Bosticardo M; Kenney H; Castagnoli R; Slade CA; Boztug K; Mahlaoui N; Latour S; Abraham RS; Lougaris V; Hauck F; Sediva A; Atschekzei F; Sogkas G; Poli MC; Slatter MA; Palterer B; Keller MD; Pinzon-Charry A; Sullivan A; Droney L; Suan D; Wong M; Kane A; Hu H; Ma C; Grombirikova H; Ciznar P; Dalal I; Aladjidi N; Hie M; Lazaro E; Franco J; Keles S; Malphettes M; Pasquet M; Maccari ME; Meinhardt A; Ikinciogullari A; Shahrooei M; Celmeli F; Frosk P; Goodnow CC; Gray PE; Belot A; Kuehn HS; Rosenzweig SD; Miyara M; Licciardi F; Servettaz A; Barlogis V; Le Guenno G; Herrmann V-M; Kuijpers T; Ducoux G; Sarrot-Reynauld F; Schuetz C; Cunningham-Rundles C; Rieux-Laucat F; Tangye SG; Sobacchi C; Doffinger R; Warnatz K; Grimbacher B; Fieschi C; Berteloot L; Bryant VL; Assant ST; Su H; Neven B; Abel L; Zhang Q; Boisson B; Cobat A; Jouanguy E; Kampe O; Bastard P; Roifman CM; Landegren N; Notarangelo LD; Anderson MS; Casanova J-L; Puel A
• Preprint: MEDRXIV. 2023

  A systematic investigation into the non-genetic and genetic factors affecting the human anti-viral antibody repertoire

  Olin A; Jaquaniello A; Tan Z; Pou C; Dubois F; Charbit B; Bloch E; White M; Rotival M; Brodin P; Duffy D; Patin E; Quintana-Murci L; Consortium MI
• Journal article: CIRCULATION. 2023;148:a16646

  Evidence of Protein Dysregulation in Patients With Post-Acute COVID-19 Syndrome With- and Without Postural Orthostatic Tachycardia Syndrome

  Zhao A; Mahdi A; Fredengren E; Fedorowski A; Braunschweig F; Brodin P; Nygren-Bonnier M; Runold M; Bruchfeld J
• Thesis / dissertation: 2023

  Immune variation in infectious disease and during development early in life

  Rodriguez, Lucie Solène Tiaré
• Review: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(10):1271-1285

  The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS)

  Shakoory B; Geerlinks A; Wilejto M; Kernan K; Hines M; Romano M; Piskin D; Ravelli A; Sinha R; Aletaha D; Allen C; Bassiri H; Behrens EM; Carcillo J; Carl L; Chatham W; Cohen JI; Cron RQ; Drewniak E; Grom AA; Henderson LA; Horne A; Jordan MB; Nichols KE; Schulert G; Vastert S; Demirkaya E; Goldbach-Mansky R; de Benedetti F; Marsh RA; Canna SW
• Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(10):1714-1732

  The 2022 EULAR/ACR Points to Consider at the Early Stages of Diagnosis and Management of Suspected Haemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome (HLH/MAS)

  Shakoory B; Geerlinks A; Wilejto M; Kernan K; Hines M; Romano M; Piskin D; Ravelli A; Sinha R; Aletaha D; Allen C; Bassiri H; Behrens EM; Carcillo J; Carl L; Chatham W; Cohen JI; Cron RQ; Drewniak E; Grom AA; Henderson LA; Horne A; Jordan MB; Nichols KE; Schulert G; Vastert S; Demirkaya E; Goldbach-Mansky R; de Benedetti F; Marsh RA; Canna SW
• Review: SEMINARS IN IMMUNOLOGY. 2023;69:101794

  Immune responses to SARS-CoV-2 infection and vaccination in children

  Brodin P
• Journal article: JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2023;159:104065-30

  Immune system adaptation during gender-affirming testosterone treatment

  Consiglio C; Tadepally L; Sardh F; Forlin R; Wang J; Tan Z; Barcenilla H; Rodriguez L; Sugrue J; Noori P; Paez LP; Gonzalez L; Mugabo CH; Johnsson A; Hallgren A; Pou C; Chen Y; Mikes J; James A; Dahlqvist P; Wahlberg J; Hagelin A; Holmberg M; Degerblad M; Isaksson M; Duffy D; Kampe O; Landegren N; Brodin P
• Article: ACTA PHYSIOLOGICA. 2023;239(1):e13982

  FiNuTyper: Design and validation of an automated deep learning-based platform for simultaneous fiber and nucleus type analysis in human skeletal muscle

  Lundquist A; Lazar E; Han NS; Emanuelsson EB; Reitzner SM; Chapman MA; Shirokova V; Alkass K; Druid H; Petri S; Sundberg CJ; Bergmann O
• Article: ISCIENCE. 2023;26(8):107422

  Integrated analysis of whole blood oxylipin and cytokine responses after bacterial, viral, and T cell stimulation reveals new immune networks.

  Villain E; Chanson A; Mainka M; Kampschulte N; Le Faouder P; Bertrand-Michel J; Brandolini-Bulon M; Charbit B; Musvosvi M; Bilek N; Scriba TJ; Quintana-Murci L; Schebb NH; Duffy D; Gladine C; Milieu Interieur Consortium
• Review: TRENDS IN IMMUNOLOGY. 2023;44(8):577-584

  Making human immune systems more interpretable through systems immunology

  Forlin R; James A; Brodin P
• Article: IMMUNITY. 2023;56(6):1255-1268.e5

  Age-dependent differences in efferocytosis determine the outcome of opsonophagocytic protection from invasive pathogens

  Bee GCW; Lokken-Toyli KL; Yeung ST; Rodriguez L; Zangari T; Anderson EE; Ghosh S; Rothlin CV; Brodin P; Khanna KM; Weiser JN
• Preprint: BIORXIV. 2023

  Scalablein-vitroimmunostimulation of human blood for in-depth profiling of acute immune response effects

  Reitzner SM; Brodin P; Mikeš J
• Preprint: BIORXIV. 2023

  Molecular Pixelation: Single cell spatial proteomics by sequencing

  Karlsson F; Kallas T; Thiagarajan D; Karlsson M; Schweitzer M; Navarro JF; Leijonancker L; Geny S; Pettersson E; Rhomberg-Kauert J; Granillo MG; Bunz J; Dahlberg J; Simonetti M; Sathe P; Brodin P; Barrio AM; Fredriksson S
• Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2023;41(16_suppl):3110

  First-in-human (FIH) phase I dose escalation study (part A) of the first oral allosteric modulator of phosphoinositide 3-kinase inhibitor delta (PI3Kδ) roginolisib in patients with advanced cancer and dose confirmation in uveal melanoma (part B).

  Di Giacomo AM; Santangelo F; Amato G; Simonetti E; Graham J; Lahn MMF; Di Conza G; Hammett T; Zorrilla R; Durini M; Tan Z; Tadepally L; Brodin P; Occhipinti M; Simonelli M; Carlo-Stella C; Santoro A; Spiliopoulou P; Evans TRJ; Maio M
• Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1_Supplement):233.07

  Immune system perturbations in patients with severe long COVID

  Rodriguez L; Tan Z; Lakshmikanth T; Wang J; Barcenilla H; Gonzalez L; Mugabo C; Johnsson A; Chen Y; Mikes J; Landegren N; Runold M; Bruchfeld J; Brodin P
• Article: ACR OPEN RHEUMATOLOGY. 2023;5(5):277-284

  Risk of Psychiatric Disorders in Juvenile Idiopathic Arthritis: Population- and Sibling-Controlled Cohort and Cross-Sectional Analyses

  Delcoigne B; Horne A; Askling J; Askling J
• Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2023;220(5):e20220170

  Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia

  Garcia-Garcia A; de Diego RP; Flores C; Rinchai D; Sole-Violan J; Deya-Martinez A; Garcia-Solis B; Lorenzo-Salazar JM; Hernandez-Brito E; Lanz A-L; Moens L; Bucciol G; Almuqamam M; Domachowske J; Colino E; Santos-Perez JL; Marco F; Pignata C; Bousfiha A; Turvey S; Bauer S; Haerynck F; Ocejo-Vinyals JG; Lendinez F; Prader S; Naumann-Bartsch N; Pachlopnik Schmid J; Biggs C; Hildebrand K; Dreesman A; Cardenes MA; Ailal F; Benhsaien I; Giardino G; Molina-Fuentes A; Fortuny C; Madhavarapu S; Conway D; Prando C; Schidlowski L; Alvarez MTMDS; Alfaro R; de Castro FR; Meyts I; Hauck F; Puel A; Bastard P; Boisson B; Jouanguy E; Abel L; Cobat A; Zhang Q; Casanova J-L; Alsina L; Rodriguez-Gallego C
• Article: THE LANCET REGIONAL HEALTH. EUROPE. 2023;28:100608

  Ambient air pollution exposure linked to long COVID among young adults: a nested survey in a population-based cohort in Sweden

  Yu Z; Ekstrom S; Bellander T; Ljungman P; Pershagen G; Eneroth K; Kull I; Bergstrom A; Georgelis A; Stafoggia M; Gruzieva O; Melen E
• Preprint: BIORXIV. 2023

  Molecular profiling of high-level athlete skeletal muscle after acute exercise – a systems biology approach

  Reitzner S; Emanuelsson E; Arif M; Kaczkowski B; Kwon ATJ; Mardinoglu A; Arner E; Chapman M; Sundberg CJ
• Article: GENOME MEDICINE. 2023;15(1):22

  Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

  Matuozzo D; Talouarn E; Marchal A; Zhang P; Manry J; Seeleuthner Y; Zhang Y; Bolze A; Chaldebas M; Milisavljevic B; Gervais A; Bastard P; Asano T; Bizien L; Barzaghi F; Abolhassani H; Abou Tayoun A; Aiuti A; Alavi Darazam I; Allende LM; Alonso-Arias R; Arias AA; Aytekin G; Bergman P; Bondesan S; Bryceson YT; Bustos IG; Cabrera-Marante O; Carcel S; Carrera P; Casari G; Chaibi K; Colobran R; Condino-Neto A; Covill LE; Delmonte OM; El Zein L; Flores C; Gregersen PK; Gut M; Haerynck F; Halwani R; Hancerli S; Hammarstroem L; Hatipoglu N; Karbuz A; Keles S; Kyheng C; Leon-Lopez R; Franco JL; Mansouri D; Martinez-Picado J; Metin Akcan O; Migeotte I; Morange P-E; Morelle G; Martin-Nalda A; Novelli G; Novelli A; Ozcelik T; Palabiyik F; Pan-Hammarstroem Q; de Diego RP; Planas-Serra L; Pleguezuelo DE; Prando C; Pujol A; Reyes LF; Riviere JG; Rodriguez-Gallego C; Rojas J; Rovere-Querini P; Schlueter A; Shahrooei M; Sobh A; Soler-Palacin P; Tandjaoui-Lambiotte Y; Tipu I; Tresoldi C; Troya J; van de Beek D; Zatz M; Zawadzki P; Al-Muhsen SZ; Alosaimi MF; Alsohime FM; Baris-Feldman H; Butte MJ; Constantinescu SN; Cooper MA; Dalgard CL; Fellay J; Heath JR; Lau Y-L; Lifton RP; Maniatis T; Mogensen TH; von Bernuth H; Lermine A; Vidaud M; Boland A; Deleuze J-F; Nussbaum R; Kahn-Kirby A; Mentre F; Tubiana S; Gorochov G; Tubach F; Hausfater P; Effort COVIDHG; Meyts I; Zhang S-Y; Puel A; Notarangelo LD; Boisson-Dupuis S; Su HC; Boisson B; Jouanguy E; Casanova J-L; Zhang Q; Abel L; Cobat A
• Review: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;151(4):832-840

  Inherited and acquired errors of type I interferon immunity govern susceptibility to COVID-19 and multisystem inflammatory syndrome in children.

  Bucciol G; COVID Human Genetic Effort; Meyts I
• Review: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;151(4):818-831

  Impact of SARS-CoV-2 infection and COVID-19 on patients with inborn errors of immunity

  Tangye SG
• Article: THE LANCET RHEUMATOLOGY. 2023;5(4):e184-e199

  Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study

  Channon-Wells S; Vito O; McArdle AJ; Seaby EG; Patel H; Shah P; Pazukhina E; Wilson C; Broderick C; D'Souza G; Keren I; Nijman RG; Tremoulet A; Munblit D; Ulloa-Gutierrez R; Carter MJ; Ramnarayan P; De T; Hoggart C; Whittaker E; Herberg JA; Kaforou M; Cunnington AJ; Blyuss O; Levin M
• Preprint: BIORXIV. 2023

  Circulating immune cell populations at rest and in response to acute endurance exercise in young adults with cerebral palsy

  Kruse A; Imery I; Corell L; Hjalmarsson E; Fernandez-Gonzalo R; von Walden F; Reitzner S
• Editorial comment: SCIENCE. 2023;379(6632):538-539

  Exaggerated responses to a virus long gone Multisystem inflammatory syndrome in children is caused by abnormal cell activation

  Brodin P
• Article: SCIENCE. 2023;379(6632):eabo3627-20

  Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children

  Lee D; Le Pen J; Yatim A; Dong B; Aquino Y; Ogishi M; Pescarmona R; Talouarn E; Rinchai D; Zhang P; Perret M; Liu Z; Jordan I; Bozdemir SE; Bayhan GI; Beaufils C; Bizien L; Bisiaux A; Lei W; Hasan M; Chen J; Gaughan C; Asthana A; Libri V; Luna JM; Jaffre F; Hoffmann HH; Michailidis E; Moreews M; Seeleuthner Y; Bilguvar K; Mane S; Flores C; Zhang Y; Arias AA; Bailey R; Schluter A; Milisavljevic B; Bigio B; Le Voyer T; Materna M; Gervais A; Moncada-Velez M; Pala F; Lazarov T; Levy R; Neehus A-L; Rosain J; Peel J; Chan Y-H; Morin M-P; Pino-Ramirez RM; Belkaya S; Lorenzo L; Anton J; Delafontaine S; Toubiana J; Bajolle F; Fumado V; DeDiego ML; Fidouh N; Rozenberg F; Perez-Tur J; Chen S; Evans T; Geissmann F; Lebon P; Weiss SR; Bonnet D; Duval X; Pan-Hammarstrom Q; Planas AM; Meyts I; Haerynck F; Pujol A; Sancho-Shimizu V; Dalgard CL; Bustamante J; Puel A; Boisson-Dupuis S; Boisson B; Maniatis T; Zhang Q; Bastard P; Notarangelo L; Beziat V; de Diego RP; Rodriguez-Gallego C; Su HC; Lifton RP; Jouanguy E; Cobat A; Alsina L; Keles S; Haddad E; Abel L; Belot A; Quintana-Murci L; Rice CM; Silverman RH; Zhang S-Y; Casanova J-L
• Article: OXFORD OPEN IMMUNOLOGY. 2023;4(1):iqad003

  Achieving symptom relief in patients with myalgic encephalomyelitis by targeting the neuro-immune interface and optimizing disease tolerance.

  Rodriguez L; Pou C; Lakshmikanth T; Zhang J; Mugabo CH; Wang J; Mikes J; Olin A; Chen Y; Rorbach J; Juto J-E; Li TQ; Julin P; Brodin P
• Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2023;41(16)

  First-in-human (FIH) phase I dose escalation study (part A) of the first oral allosteric modulator of phosphoinositide 3-kinase inhibitor delta (PI3Kδ) roginolisib in patients with advanced cancer and dose confirmation in uveal melanoma (part B).

  Di Giacomo AM; Santangelo F; Amato G; Simonetti E; Graham J; Lahn MMF; Di Conza G; Hammett T; Zorrilla R; Durini M; Tan Z; Tadepally L; Brodin P; Occhipinti M; Simonelli M; Carlo-Stella C; Santoro A; Spiliopoulou P; Evans TRJ; Maio M
• Conference publication: ANNALS OF NUTRITION AND METABOLISM. 2023;79:340

  The effects of 20-week exercise on whole-blood genome-wide DNA methylation profile in children with overweight/obesity

  Anguita-Ruiz A; Plaza-Florido A; Altmae S; Aguilera CM; Reitzner SM; Sundberg CJ; Ortega FB
• Conference publication: ARTHRITIS & RHEUMATOLOGY. 2023;75:4913-4915

  Anifrolumab Normalizes the Type I Interferon Signature in a Cohort of Patients with Type I Interferonopathies

  Alehashemi S; Baumgardner A; Shakoory B; de Jesus AA; Park S; Uss K; Robles MP; Palmblad K; Horne A; Brodin P; Akoghlanian S; Abraham R; Mustillo P; Barillas-Arias L; Heras A; Muskardin TW; Lawrence MG; Mannem HC; Nolan BE; Canna S; Reinhardt A; Binstadt B; Goldbach-Mansky R
• Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2023;43(1):136-150

  Three Adult Cases of STAT1 Gain-of-Function with Chronic Mucocutaneous Candidiasis Treated with JAK Inhibitors

  Borgstrom EW; Edvinsson M; Perez LP; Norlin AC; Enoksson SL; Hansen S; Fasth A; Friman V; Kampe O; Mansson R; Estupinan HY; Qing W; Tan Z; Lakshmikanth T; Smith CIE; Brodin P; Bergman P
• Review: CAMBRIDGE PRISMS: PRECISION MEDICINE. 2023;1:e25

  Making inroads to precision medicine for the treatment of autoimmune diseases: Harnessing genomic studies to better diagnose and treat complex disorders.

  Baglaenko Y; Wagner C; Bhoj VG; Brodin P; Gershwin ME; Graham D; Invernizzi P; Kidd KK; Korsunsky I; Levy M; Mammen AL; Nizet V; Ramirez-Valle F; Stites EC; Williams MS; Wilson M; Rose NR; Ladd V; Sirota M
• Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)

  Immune system perturbations in patients with severe long COVID

  Rodriguez L; Tan Z; Lakshmikanth T; Wang J; Barcenilla H; Gonzalez L; Mugabo C; Johnsson A; Chen Y; Mikes J; Landegren N; Runold M; Bruchfeld J; Brodin P
• Article: PLOS ONE. 2023;18(12):e0295838

  Anakinra or tocilizumab in patients admitted to hospital with severe covid-19 at high risk of deterioration (IMMCoVA): A randomized, controlled, open-label trial

  Sunden-Cullberg J; Chen P; Habel H; Skorup P; Janols H; Rasmuson J; Niward K; Balkhed AO; Chatzidionysiou K; Asgeirsson H; Blennow O; Parke A; Svensson A-K; Muvva JR; Ljunggren H-G; Horne A-C; Aden U; Henter J-I; Sonnerborg A; Vesterbacka J; Nowak P; Lampa J
• Preprint: BIORXIV. 2022

  FiNuTyper: an automated deep learning-based platform for simultaneous fiber and nucleus type analysis in human skeletal muscle

  Lundquist A; Lázár E; Han NS; Emanuelsson E; Reitzner S; Chapman M; Alkass K; Druid H; Petri S; Sundberg CJ; Bergmann O
• Article: CELL REPORTS MEDICINE. 2022;3(11):100804

  Enhanced TLR3 responsiveness in hepatitis C virus resistant women from the Irish anti-D cohort

  Sugrue JA; Posseme C; Tan Z; Pou C; Charbit B; Bondet V; Bourke NM; Brodin P; Duffy D; O'Farrelly C
• Editorial comment: THE BMJ. 2022;379:o2750

  The challenges of doing paediatric research during the first year of the covid-19 pandemic

  Buonsenso D; Roland D; Yock-Corrales A; Gonzalez-Dambrauskas S; Brodin P; Santiago-Garcia B; Soriano-Arandes A; Koenraads M; De Luca D; Whittaker E
• Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2022;219(11):e20220514

  Autoantibodies against type I IFNs in patients with critical influenza pneumonia

  Zhang Q; Pizzorno A; Miorin L; Bastard P; Gervais A; Le Voyer T; Bizien L; Manry J; Rosain J; Philippot Q; Goavec K; Padey B; Cupic A; Laurent E; Saker K; Vanker M; Saerekannu K; Garcia-Salum T; Ferres M; Le Corre N; Sanchez-Cespedes J; Balsera-Manzanero M; Carratala J; Retamar-Gentil P; Abelenda-Alonso G; Valiente A; Tiberghien P; Zins M; Debette S; Meyts I; Haerynck F; Castagnoli R; Notarangelo LD; Gonzalez-Granado LI; Dominguez-Pinilla N; Andreakos E; Triantafyllia V; Rodriguez-Gallego C; Sole-Violan J; Ruiz-Hernandez JJ; Rodriguez de Castro F; Ferreres J; Briones M; Wauters J; Vanderbeke L; Feys S; Kuo C-Y; Lei W-T; Ku C-L; Tal G; Etzioni A; Hanna S; Fournet T; Casalegno J-S; Queromes G; Argaud L; Javouhey E; Rosa-Calatrava M; Cordero E; Aydillo T; Medina RA; Kisand K; Puel A; Jouanguy E; Abel L; Cobat A; Trouillet-Assant S; Garcia-Sastre A; Casanova J-L
• Article: NATURE COMMUNICATIONS. 2022;13(1):5895

  The immune factors driving DNA methylation variation in human blood

  Bergstedt J; Azzou SAK; Tsuo K; Jaquaniello A; Urrutia A; Rotival M; Lin DTS; MacIsaac JL; Kobor MS; Albert ML; Duffy D; Patin E; Quintana-Murci L
• Article: MOLECULAR ONCOLOGY. 2022;16(19):3452-3464

  Prostate cancer disease recurrence after radical prostatectomy is associated with HLA type and local cytomegalovirus immunity

  Classon J; Zamboni M; Engblom C; Alkass K; Mantovani G; Pou C; Nkulikiyimfura D; Brodin P; Druid H; Mold J; Frisen J
• Editorial comment: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(7):1354-1359

  Decoding the Human Genetic and Immunological Basis of COVID-19 mRNA Vaccine-Induced Myocarditis

  Bolze A; Mogensen TH; Zhang S-Y; Abel L; Andreakos E; Arkin LM; Borghesi A; Brodin P; Hagin D; Novelli G; Okada S; Peter J; Renia L; Severe K; Tiberghien P; Vinh DC; Cirulli ET; Casanova J-L; Hsieh EWY
• Article: BMC PEDIATRICS. 2022;22(1):565

  Transplantation of maternal intestinal flora to the newborn after elective cesarean section (SECFLOR): study protocol for a double blinded randomized controlled trial

  Carpen N; Brodin P; de Vos WM; Salonen A; Kolho K-L; Andersson S; Helve O
• Journal article: CLINICAL CANCER RESEARCH. 2022;28(18_Supplement):a039

  Abstract A039: IGFBP5 is induced by tumor-suppressive naïve stromal cells and regulates GAS2-associated apoptosis in rhabdomyosarcoma

  Ehnman M; Katkhada K; Meng LZ; Zhang Y; Zhao B; Tong S; Kallai A; Östman A; Tobin N
• Article: SCIENTIFIC REPORTS. 2022;12(1):14937

  Selective transfer of maternal antibodies in preterm and fullterm children

  Dolatshahi S; Butler AL; Pou C; Henckel E; Bernhardsson AK; Gustafsson A; Bohlin K; Shin SA; Lauffenburger DA; Brodin P; Alter G
• Article: ACR OPEN RHEUMATOLOGY. 2022;4(9):804-810

  Treatment of Multisystem Inflammatory Syndrome in Children: Understanding Differences in Results of Comparative Effectiveness Studies.

  Melgar M; Seaby EG; McArdle AJ; Young CC; Campbell AP; Murray NL; Patel MM; Levin M; Randolph AG; Son MBF; BATS Consortium and the Overcoming COVID-19 Invest
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9S):392-393

  Skeletal Muscle Proteomics Comparison Between Long-term Trained And Untrained Men And Women

  Chapman M; Emanuelsson E; Arif M; Lakhia Z; Reitzner S; Mardinoglu A; Sundberg CJ
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9S):628

  Metabolomic Response To Acute Endurance And Resistance Exercise In Life-long Trained Athletes And Untrained Individuals

  Reitzner SM; Arif M; Emanuelsson E; Chapman M; Mardinoglu A; Sundberg CJ
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9S):389

  MRI Characterization Of Skeletal Muscle Size And Fatty Infiltration In Long-term Trained And Untrained Individuals

  Emanuelsson EB; Berry D; Reitzner SM; Arif M; Mardinoglu A; Gustafsson T; Ward S; Sundberg CJ; Chapman MA
• Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;77(8):2415-2430

  Autoantibodies in COVID-19 correlate with antiviral humoral responses and distinct immune signatures

  Taeschler P; Cervia C; Zurbuchen Y; Hasler S; Pou C; Tan Z; Adamo S; Raeber ME; Bachli E; Rudiger A; Stussi-Helbling M; Huber LC; Brodin P; Nilsson J; Probst-Muller E; Boyman O
• Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2022;219(8):e20220131

  Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

  Zhang Q; Matuozzo D; Le Pen J; Lee D; Moens L; Asano T; Bohlen J; Liu Z; Moncada-Velez M; Kendir-Demirkol Y; Jing H; Bizien L; Marchal A; Abolhassani H; Delafontaine S; Bucciol G; Bayhan GI; Keles S; Kiykim A; Hancerli S; Haerynck F; Florkin B; Hatipoglu N; Ozcelik T; Morelle G; Zatz M; Ng LFP; Lye DC; Young BE; Leo Y-S; Dalgard CL; Lifton RP; Renia L; Meyts I; Jouanguy E; Hammarstrom L; Pan-Hammarstrom Q; Boisson B; Bastard P; Su HC; Boisson-Dupuis S; Abel L; Rice CM; Zhang S-Y; Cobat A; Casanova J-L
• Article: THE LANCET REGIONAL HEALTH. EUROPE. 2022;19:100443

  Risk factors for multisystem inflammatory syndrome in children - A population-based cohort study of over 2 million children

  Rhedin S; Lundholm C; Horne A; Smew AI; Osvald EC; Haddadi A; Alfven T; Kahn R; Krol P; Brew BH; Almqvist C
• Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2022;219(7):e20220202

  Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency

  Campbell TM; Liu Z; Zhang Q; Moncada-Velez M; Covill LE; Zhang P; Darazam IA; Bastard P; Bizien L; Bucciol G; Enoksson SL; Jouanguy E; Karabela SN; Khan T; Kendir-Demirkol Y; Augusto Arias A; Mansouri D; Marits P; Marr N; Migeotte I; Moens L; Ozcelik T; Pellier I; Sendel A; Senoglu S; Shahrooei M; Smith CIE; Vandernoot I; Willekens K; Yasar KK; Bergman P; Abel L; Cobat A; Casanova J-L; Meyts I; Bryceson YT
• Article: PHYSIOLOGICAL REPORTS. 2022;10(14):e15398

  MRI characterization of skeletal muscle size and fatty infiltration in long--term trained and untrained individuals

  Emanuelsson EB; Berry DB; Reitzner SM; Arif M; Mardinoglu A; Gustafsson T; Ward SR; Sundberg CJ; Chapman MA
• Letter: THE LANCET GASTROENTEROLOGY AND HEPATOLOGY. 2022;7(7):594-595

  Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens

  Brodin P; Arditi M
• Article: CELL REPORTS. 2022;39(13):110989

  Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation

  Posseme C; Llibre A; Charbit B; Bondet V; Rouilly V; Saint-Andre V; Boussier J; Bergstedt J; Smith N; Townsend L; Sugrue JA; Cheallaigh CN; Conlon N; Rotival M; Kobor MS; Mottez E; Pol S; Patin E; Albert ML; Quintana-Murci L; Duffy D
• Journal article: FRONTIERS IN SYSTEMS BIOLOGY. 2022;2:918792

  Data Availability of Open T-Cell Receptor Repertoire Data, a Systematic Assessment

  Huang Y-N; Patel NA; Mehta JH; Ginjala S; Brodin P; Gray CM; Patel YM; Cowell LG; Burkhardt AM; Mangul S
• Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2022;40(16_suppl):3107

  First-in-human (FIH) phase I study of the highly selective phosphoinositide 3-kinase inhibitor delta (PI3Kδ) inhibitor IOA-244 in patients with advanced cancer: Safety, activity, pharmacokinetic (PK), and pharmacodynamic (PD) results.

  Di Giacomo AM; Santangelo F; Amato G; Simonetti E; Graham J; Lahn MMF; van der Veen LA; Johnson Z; Pickering CA; Durini M; Tan Z; Tadepally L; Brodin P; Occhipinti M; Simonelli M; Carlo-Stella C; Santoro A; Spiliopoulou P; Evans TRJ; Maio M
• Review: SCIENCE. 2022;376(6596):945-950

  Immune-microbe interactions early in life: A determinant of health and disease long term

  Brodin P
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(21):e2200413119

  The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

  Manry J; Bastard P; Gervais A; Le Voyer T; Rosain J; Philippot Q; Michailidis E; Hoffmann H-H; Eto S; Garcia-Prat M; Bizien L; Parra-Martinez A; Yang R; Haljasmagi L; Migaud M; Sarekannu K; Maslovskaja J; de Prost N; Tandjaoui-Lambiotte Y; Luyt C-E; Amador-Borrero B; Gaudet A; Poissy J; Morel P; Richard P; Cognasse F; Troya J; Trouillet-Assant S; Belot A; Saker K; Garcon P; Riviere JG; Lagier J-C; Gentile S; Rosen LB; Shaw E; Morio T; Tanaka J; Dalmau D; Tharaux P-L; Sene D; Stepanian A; Megarbane B; Triantafyllia V; Fekkar A; Heath JR; Franco JL; Anaya J-M; Sole-Violan J; Imberti L; Biondi A; Bonfanti P; Castagnoli R; Delmonte OM; Zhang Y; Snow AL; Holland SM; Biggs CM; Moncada-Velez M; Arias AA; Lorenzo L; Boucherit S; Anglicheau D; Planas AM; Haerynck F; Duvlis S; Ozcelik T; Keles S; Bousfiha AA; El Bakkouri J; Ramirez-Santana C; Paul S; Pan-Hammarstrom Q; Hammarstrom L; Dupont A; Kurolap A; Metz CN; Aiuti A; Casari G; Lampasona V; Ciceri F; Barreiros LA; Dominguez-Garrido E; Vidigal M; Zatz M; van de Beek D; Sahanic S; Tancevski I; Stepanovskyy Y; Boyarchuk O; Nukui Y; Tsumura M; Vidaur L; Tangye SG; Burrel S; Duffy D; Quintana-Murci L; Klocperk A; Kann NY; Shcherbina A; Lau Y-L; Leung D; Coulongeat M; Marlet J; Koning R; Reyes LF; Chauvineau-Grenier A; Venet F; Monneret G; Nussenzweig MC; Arrestier R; Boudhabhay I; Baris-Feldman H; Hagin D; Wauters J; Meyts I; Dyer AH; Kennelly S; Bourkeh NM; Halwan R; Sharif-Askar FS; Dorgham K; Sallette J; Sedkaoui SM; AlKhater S; Rigo-Bonnin R; Morandeira F; Roussel L; Vinh DC; Erikstrup C; Condino-Neto A; Prando C; Bondarenko A; Spaan AN; Gilardin L; Fellay J; Lyonnet S; Bilguvar K; Lifton RP; Mane S; Anderson MS; Boisson B; Beziat V; Zhang S-Y; Andreakos E; Hermine O; Pujol A; Peterson P; Mogensen TH; Rowen L; Mond J; Debette S; de Lamballerie X; Burdet C; Bouadma L; Zins M; Soler-Palacin P; Colobran R; Gorochov G; Solanich X; Susen S; Martinez-Picado J; Raoult D; Vasse M; Gregersen PK; Piemonti L; Rodriguez-Gallego C; D Notarangelo L; Su HC; Kisand K; Okada S; Puel A; Jouanguy E; Rice CM; Tiberghien P; Zhang Q; Casanova J-L; Abel L; Cobat A
• Review: CRITICAL CARE MEDICINE. 2022;50(5):860-872

  Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults

  Hines MR; Greenwood TVB; Beutel G; Beutel K; Hays JA; Horne A; Janka G; Jordan MB; van Laar JAM; Lachmann G; Lehmberg K; Machowicz R; Miettunen P; La Rosee P; Shakoory B; Zinter MS; Henter J-I
• Letter: NATURE MEDICINE. 2022;28(5):879-882

  Studying severe long COVID to understand post-infectious disorders beyond COVID-19

  Brodin P; Casari G; Townsend L; O'Farrelly C; Tancevski I; Loeffler-Ragg J; Mogensen TH; Casanova JL
• Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;77(5):1583-1595

  Longitudinal analyses of development of the immune system during the first five years of life in relation to lifestyle

  Olin A; Acevedo N; Lakshmikanth T; Chen Y; Johansson C; Alm J; Scheynius A; Brodin P
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: GLOBAL. 2022;1(2):37-42

  Lung function before and after COVID-19 in young adults: A population-based study.

  Mogensen I; Hallberg J; Björkander S; Du L; Zuo F; Hammarström L; Pan-Hammarström Q; Ekström S; Georgelis A; Palmberg L; Janson C; Bergström A; Melén E; Kull I; BAMSE COVID-19 Study Group
• Preprint: BIORXIV. 2022

  Data availability of open T-cell receptor repertoire data, a systematic assessment

  Huang Y-N; Patel NA; Mehta JH; Ginjala S; Brodin P; Gray C; Patel Y; Cowell L; Burkhardt A; Mangul S
• Article: GENES AND IMMUNITY. 2022;23(2):93-98

  Rhesus negative males have an enhanced IFNγ-mediated immune response to influenza A virus.

  Sugrue JA; Smith M; Posseme C; Charbit B; Milieu Interieur Consortium; Bourke NM; Duffy D; O'Farrelly C
• Article: CHILD PSYCHIATRY AND HUMAN DEVELOPMENT. 2022;53(2):354-364

  A Two-to-Five Year Follow-Up of a Pediatric Acute-Onset Neuropsychiatric Syndrome Cohort

  Gromark C; Hesselmark E; Djupedal IG; Silverberg M; Horne A; Harris RA; Serlachius E; Mataix-Cols D
• Article: JAMA NETWORK OPEN. 2022;5(4):e228109

  Association of Short-term Air Pollution Exposure With SARS-CoV-2 Infection Among Young Adults in Sweden

  Yu Z; Bellander T; Bergstrom A; Dillner J; Eneroth K; Engardt M; Georgelis A; Kull I; Ljungman P; Pershagen G; Stafoggia M; Melen E; Gruzieva O
• Review: NATURE. 2022;603(7902):587-598

  Human genetic and immunological determinants of critical COVID-19 pneumonia

  Zhang Q; Bastard P; Cobat A; Casanova J-L
• Preprint: BIORXIV. 2022

  Graph deep learning reveals multiple signal pathways activated in anti-citrullinated protein antibodies stimulated synoviocytes

  Sun M; Chen Y; Brodin P; Catrina A
• Preprint: RESEARCH SQUARE. 2022

  Three adult cases of STAT1-gain-of-function with chronic mucocutaneous candidiasis treated with JAK inhibitors

  Borgström EW; Edvinsson M; Perez LP; Norlin A-C; Hansen S; Fasth A; Friman V; Kämpe O; Månsson R; Tan Z; Smith CIE; Brodin P; Bergman P
• Article: GENOME MEDICINE. 2022;14(1):28

  Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes.

  Caron B; Patin E; Rotival M; Charbit B; Albert ML; Quintana-Murci L; Duffy D; Rausell A; Milieu Intérieur Consortium
• Article: RHEUMATOLOGY. 2022;61(3):1228-1232

  Juvenile idiopathic arthritis, marriage and parenthood: a nationwide matched cohort study

  Bruze G; Askling J; Horne A; Neovius M
• Review: IMMUNITY. 2022;55(2):201-209

  SARS-CoV-2 infections in children: Understanding diverse outcomes

  Brodin P
• Article: NATURE IMMUNOLOGY. 2022;23(2):159-164

  A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection

  Andreakos E; Abel L; Vinh DC; Kaja E; Drolet BA; Zhang Q; O'Farrelly C; Novelli G; Rodriguez-Gallego C; Haerynck F; Prando C; Pujol A; Su HC; Casanova J-L; Spaan AN; Bastard P; Biggs CM; Bigio B; Boisson B; Bolze A; Bondarenko A; Brodin P; Chakravorty S; Christodoulou J; Cobat A; Condino-Neto A; Constantinescu SN; Feldman HB; Fellay J; Halwani R; Jouanguy E; Lau Y-L; Meyts I; Mogensen TH; Okada S; Okamoto K; Ozcelik T; Pan-Hammarstrom Q; Planas AM; Puel A; Quintana-Murci L; Renia L; Resnick I; Sediva A; Shcherbina A; Slaby O; Tancevski I; Turvey SE; Uddin KMF; van de Beek D; Zatz M; Zawadzki P; Zhang S-Y
• Corrigendum: NATURE IMMUNOLOGY. 2022;23(2):341

  A global effort to dissect the human genetic basis of resistance to SARS-CoV-2 infection (Oct, 10.1038/s41590-021-01030-z, 2021)

  Andreakos E; Abel L; Vinh DC; Kaja E; Drolet BA; Zhang Q; O'Farrelly C; Novelli G; Rodriguez-Gallego C; Haerynck F; Prando C; Pujol A; Su HC; Casanova J-L; Spaan AN
• Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2022;111(2):354-362

  Population-based study of multisystem inflammatory syndrome associated with COVID-19 found that 36% of children had persistent symptoms

  Kahn R; Berg S; Berntson L; Berthold E; Brodin P; Backstrom F; Compagno M; Fasth A; Framme JL; Horne A; Hattting J; Krol P; Kukka AJ; Mossberg M; Mansson B; Nordenhall C; Nordstrom SI; Nystrom FK; Palmblad K; Rasti R; Rudolph A; Rydenman K; Sundberg E; Save-Soderbergh E; Altman M
• Preprint: MEDRXIV. 2022

  Autoantibodies in COVID-19 correlate with anti-viral humoral responses and distinct immune signatures

  Taeschler P; Cervia C; Zurbuchen Y; Hasler S; Pou C; Tan Z; Adamo S; Raeber ME; Bächli E; Rudiger A; Stüssi-Helbling M; Huber LC; Brodin P; Nilsson J; Probst-Müller E; Boyman O
• Conference publication: CLINICAL CANCER RESEARCH. 2022;28(18)

  IGFBP5 is induced by tumor-suppressive naive stromal cells and regulates GAS2-associated apoptosis in rhabdomyosarcoma

  Ehnman M; Katkhada K; Meng LZ; Zhang Y; Zhao B; Tong S; Kallai A; Ostman A; Tobin N
• Conference publication: JOURNAL OF CLINICAL ONCOLOGY. 2022;40(16)

  First-in-human (FIH) phase I study of the highly selective phosphoinositide 3-kinase inhibitor delta (PI3Kδ) inhibitor IOA-244 in patients with advanced cancer: Safety, activity, pharmacokinetic (PK), and pharmacodynamic (PD) results.

  Di Giacomo AM; Santangelo F; Amato G; Simonetti E; Graham J; Lahn MMF; Van der Veen LA; Johnson Z; Pickering CA; Durini M; Tan Z; Tadepally L; Brodin P; Occhipinti M; Simonelli M; Carlo-Stella C; Santoro A; Spiliopoulou P; Evans TRJ; Maio M
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9):389

  MRI Characterization Of Skeletal Muscle Size And Fatty Infiltration In Long-term Trained And Untrained Individuals

  Emanuelsson EB; Berry D; Reitzner SM; Arif M; Mardinoglu A; Gustafsson T; Ward S; Sundberg CJ; Chapman MA
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9):628

  Metabolomic Response To Acute Endurance And Resistance Exercise In Life-long Trained Athletes And Untrained Individuals

  Reitzner SM; Arif M; Emanuelsson E; Chapman M; Mardinoglu A; Sundberg CJ
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2022;54(9):392-393

  Skeletal Muscle Proteomics Comparison Between Long-term Trained And Untrained Men And Women

  Chapman M; Emanuelsson E; Arif M; Lakhia Z; Reitzner S; Mardinoglu A; Sundberg CJ
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(1):65-75.e8

  SARS-CoV-2-specific B- and T-cell immunity in a population-based study of young Swedish adults

  Bjorkander S; Du L; Zuo F; Ekstrom S; Wang Y; Wan H; Sherina N; Schoutens L; Andrell J; Andersson N; Georgelis A; Bergstrom A; Marcotte H; Kull I; Hammarstrom L; Melen E; Pan-Hammarstrom Q
• Article: PEDIATRIC RHEUMATOLOGY. 2021;19(1):173

  Immunoprofiling of active and inactive systemic juvenile idiopathic arthritis reveals distinct biomarkers: a single-center study

  Qu H; Sundberg E; Aulin C; Neog M; Palmblad K; Horne AC; Granath F; Ek A; Melen E; Olsson M; Harris HE
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(12):2791-2796

  From Your Nose to Your Toes: A Review of Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic-Associated Pernio

  Arkin LM; Moon JJ; Tran JM; Asgan S; O'Farrelly C; Casanova J-L; Cowen EW; Mays JW; Singh AM; Drolet BA
• Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2021;32(8):1833-1842

  Virological and immunological features of SARS-COV-2 infected children with distinct symptomatology

  Cotugno N; Ruggiero A; Pascucci GR; Bonfante F; Petrara MR; Pighi C; Cifaldi L; Zangari P; Bernardi S; Cursi L; Santilli V; Manno EC; Amodio D; Linardos G; Piccioni L; Barbieri MA; Perrotta D; Campana A; Dona D; Giaquinto C; Concato C; Brodin P; Rossi P; De Rossi A; Palma P
• Article: JOURNAL OF RHEUMATOLOGY. 2021;48(10):1596-1602

  Efficacy of Moderately Dosed Etoposide in Macrophage Activation Syndrome-Hemophagocytic Lymphohistiocytosis

  Horne A; Greenwood TVB; Chiang SCC; Meeths M; Bjorklund C; Ekelund M; Erensjo P; Berg S; Hagelberg S; Bryceson YT; Andersson U; Henter J-I
• Article: SCIENCE IMMUNOLOGY. 2021;6(62):eabl4348

  X-linked recessive TLR7 deficiency in ∼1% of men under 60 years old with life-threatening COVID-19

  Asano T; Boisson B; Onodi F; Matuozzo D; Moncada-Velez M; Renkilaraj MRLM; Zhang P; Meertens L; Bolze A; Materna M; Korniotis S; Gervais A; Talouarn E; Bigio B; Seeleuthner Y; Bilguvar K; Zhang Y; Neehus A-L; Ogishi M; Pelham SJ; Le Voyer T; Rosain J; Philippot Q; Soler-Palacin P; Colobran R; Martin-Nalda A; Riviere JG; Tandjaoui-Lambiotte Y; Chaibi K; Shahrooei M; Darazam IA; Olyaei NA; Mansouri D; Palabiyik F; Ozcelik T; Novelli G; Novelli A; Casari G; Aiuti A; Carrera P; Bondesan S; Barzaghi F; Rovere-Querini P; Tresoldi C; Franco JL; Rojas J; Reyes LF; Bustos IG; Arias AA; Morelle G; Kyheng C; Troya J; Planas-Serra L; Schluter A; Gut M; Pujol A; Allende LM; Rodriguez-Gallego C; Flores C; Cabrera-Marante O; Pleguezuelo DE; de Diego RP; Keles S; Aytekin G; Akcan OM; Bryceson YT; Bergman P; Brodin P; Smole D; Smith CIE; Norlin A-C; Campbell TM; Covill LE; Hammarstrom L; Pan-Hammarstrom Q; Abolhassani H; Mane S; Marr N; Ata M; Al Ali F; Khan T; Spaan AN; Dalgard CL; Bonfanti P; Biondi A; Tubiana S; Burdet C; Nussbaum R; Kahn-Kirby A; Snow AL; Bustamante J; Puel A; Boisson-Dupuis S; Zhang S-Y; Beziat V; Lifton RP; Bastard P; Notarangelo LD; Abel L; Su HC; Jouanguy E; Amara A; Soumelis V; Cobat A; Zhang Q; Casanova J-L
• Article: SCIENCE IMMUNOLOGY. 2021;6(62):eabl4340

  Autoantibodies neutralizing type I IFNs are present in ∼4% of uninfected individuals over 70 years old and account for ∼20% of COVID-19 deaths

  Bastard P; Gervais A; Le Voyer T; Rosain J; Philippot Q; Manry J; Michailidis E; Hoffmann H-H; Eto S; Garcia-Prat M; Bizien L; Parra-Martinez A; Yang R; Haljasmagi L; Migaud M; Sarekannu K; Maslovskaja J; de Prost N; Tandjaoui-Lambiotte Y; Luyt C-E; Amador-Borrero B; Gaudet A; Poissy J; Morel P; Richard P; Cognasse F; Troya J; Trouillet-Assant S; Belot A; Saker K; Garcon P; Riviere JG; Lagier J-C; Gentile S; Rosen LB; Shaw E; Morio T; Tanaka J; Dalmau D; Tharaux P-L; Sene D; Stepanian A; Megarbane B; Triantafyllia V; Fekkar A; Heath JR; Franco JL; Anaya J-M; Sole-Violan J; Imberti L; Biondi A; Bonfanti P; Castagnoli R; Delmonte OM; Zhang Y; Snow AL; Holland SM; Biggs CM; Moncada-Velez M; Arias AA; Lorenzo L; Boucherit S; Coulibaly B; Anglicheau D; Planas AM; Haerynck F; Duvlis S; Nussbaum RL; Ozcelik T; Keles S; Bousfiha AA; El Bakkouri J; Ramirez-Santana C; Paul S; Pan-Hammarstrom Q; Hammarstrom L; Dupont A; Kurolap A; Metz CN; Aiuti A; Casari G; Lampasona V; Ciceri F; Barreiros LA; Dominguez-Garrido E; Vidigal M; Zatz M; van de Beek D; Sahanic S; Tancevski I; Stepanovskyy Y; Boyarchuk O; Nukui Y; Tsumura M; Vidaur L; Tangye SG; Burrel S; Duffy D; Quintana-Murci L; Klocperk A; Kann NY; Shcherbina A; Lau Y-L; Leung D; Coulongeat M; Marlet J; Koning R; Reyes LF; Chauvineau-Grenier A; Venet F; Monneret G; Nussenzweig MC; Arrestier R; Boudhabhay I; Baris-Feldman H; Hagin D; Wauters J; Meyts I; Dyer AH; Kennelly SP; Bourke NM; Halwani R; Sharif-Askari NS; Dorgham K; Sallette J; Sedkaoui SM; AlKhater S; Rigo-Bonnin R; Morandeira F; Roussel L; Vinh DC; Ostrowski SR; Condino-Neto A; Prando C; Bondarenko A; Spaan AN; Gilardin L; Fellay J; Lyonnet S; Bilguvar K; Lifton RP; Mane S; Anderson MS; Boisson B; Beziat V; Zhang S-Y; Andreakos E; Hermine O; Pujol A; Peterson P; Mogensen TH; Rowen L; Mond J; Debette S; de Lamballerie X; Duval X; Mentre F; Zins M; Soler-Palacin P; Colobran R; Gorochov G; Solanich X; Susen S; Martinez-Picado J; Raoult D; Vasse M; Gregersen PK; Piemonti L; Rodriguez-Gallego C; Notarangelo LD; Su HC; Kisand K; Okada S; Puel A; Jouanguy E; Rice CM; Tiberghien P; Zhang Q; Cobat A; Abel L; Casanova J-L
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;148(2):407-419

  Lung function fluctuation patterns unveil asthma and COPD phenotypes unrelated to type 2 inflammation

  Delgado-Eckert E; James A; Meier-Girard D; Kupczyk M; Andersson LI; Bossios A; Mikus M; Ono J; Izuhara K; Middelveld R; Dahlen B; Gaga M; Siafakas NM; Papi A; Beghe B; Joos G; Rabe KF; Sterk PJ; Bel EH; Johnston SL; Chanez P; Gjomarkaj M; Howarth PH; Nizankowska-Mogilnicka E; Dahlen S-E; Frey U
• Article: THE LANCET RHEUMATOLOGY. 2021;3(8):E563-E573

  Definition and validation of serum biomarkers for optimal differentiation of hyperferritinaemic cytokine storm conditions in children: a retrospective cohort study

  Kessel C; Fall N; Grom A; de Jager W; Vastert S; Strippoli R; Bracaglia C; Sundberg E; Horne A; Ehl S; Ammann S; Wouters C; Lehmberg K; De Benedetti F; Park C; Hinze C; Wittkowski H; Kessel K; Beutel K; Foell D; Holzinger D
• Article: JOURNAL OF EXPERIMENTAL AND CLINICAL CANCER RESEARCH. 2021;40(1):240

  A vision of immuno-oncology: the Siena think tank of the Italian network for tumor biotherapy (NIBIT) foundation

  Maio M; Lahn M; Di Giacomo AM; Covre A; Calabro L; Ibrahim R; Fox B
• Article: CELL. 2021;184(15):3884-3898.e11

  Bifidobacteria-mediated immune system imprinting early in life

  Henrick BM; Rodriguez L; Lakshmikanth T; Pou C; Henckel E; Arzoomand A; Olin A; Wang J; Mikes J; Tan Z; Chen Y; Ehrlich AM; Bernhardsson AK; Mugabo CH; Ambrosiani Y; Gustafsson A; Chew S; Brown HK; Prambs J; Bohlin K; Mitchell RD; Underwood MA; Smilowitz JT; German JB; Frese SA; Brodin P
• Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;148(1):96-98

  Severe COVID-19 in an APS1 patient with interferon autoantibodies treated with plasmapheresis

  Lemarquis A; Campbell T; Aranda-Guillen M; Hennings V; Brodin P; Kampe O; Blennow K; Zetterberg H; Wenneras C; Eriksson K; Landegren N; Bryceson Y; Berg S; Ekwall O
• Article: NEW ENGLAND JOURNAL OF MEDICINE. 2021;385(1):11-22

  Treatment of Multisystem Inflammatory Syndrome in Children

  McArdle AJ; Vito O; Patel H; Seaby EG; Shah P; Wilson C; Broderick C; Nijman R; Tremoulet AH; Munblit D; Ulloa-Gutierrez R; Carter MJ; De T; Hoggart C; Whittaker E; Herberg JA; Kaforou M; Cunnington AJ; Levin M
• Review: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2021;218(6):e20210446

  SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?

  Sancho-Shimizu V; Brodin P; Cobat A; Biggs CM; Toubiana J; Lucas CL; Henrickson SE; Belot A; Tangye SG; Milner JD; Levin M; Abel L; Bogunovic D; Casanova J-L; Zhang S-Y
• Editorial comment: NATURE METHODS. 2021;18(6):588-591

  Diversity in immunogenomics: the value and the challenge

  Peng K; Safonova Y; Shugay M; Popejoy AB; Rodriguez OL; Breden F; Brodin P; Burkhardt AM; Bustamante C; Cao-Lormeau V-M; Corcoran MM; Duffy D; Fuentes-Guajardo M; Fujita R; Greiff V; Jonsson VD; Liu X; Quintana-Murci L; Rossetti M; Xie J; Yaari G; Zhang W; Abedalthagafi MS; Adekoya KO; Ahmed RA; Chang W-C; Gray C; Nakamura Y; Lees WD; Khatri P; Alachkar H; Scheepers C; Watson CT; Karlsson Hedestam GB; Mangul S
• Article: LAKARTIDNINGEN. 2021;118:21136

  Viktigt att uppmärksamma MIS-A inom vuxensjukvården.

  Brodin P
• Article: MOLECULAR MEDICINE. 2021;27(1):48

  Therapeutic administration of etoposide coincides with reduced systemic HMGB1 levels in macrophage activation syndrome

  Palmblad K; Schierbeck H; Sundberg E; Horne A-C; Harris HE; Henter J-I; Andersson U
• Preprint: BIORXIV. 2021

  Stimulation with mycobacterial glycolipids and PPD reveals different innate immune response profiles in active and latent TB

  Silva C; Sundling C; Folkeson E; Fröberg G; Nobrega C; Canto-Gomes J; Chambers B; Lakshmikanth T; Brodin P; Bruchfeld J; Nigou J; Correia-Neves M; Källenius G
• Article: PSYCHONEUROENDOCRINOLOGY. 2021;126:105162

  Autoantibodies against the C-terminus of Lipopolysaccharide binding protein are elevated in young adults with psychiatric disease

  Just D; Rasmusson AJ; Nilsson P; Noreland M; Malmstrom E; Brodin P; Manberg A; Cunningham JL
• Article: ERJ OPEN RESEARCH. 2021;7(2):917-2020

  Nasal upregulation of CST1 in dog-sensitised children with severe allergic airway disease

  Kack U; Einarsdottir E; van Hage M; Asarnoj A; James A; Nopp A; Krjutskov K; Katayama S; Kere J; Lilja G; Soderhall C; Konradsen JR
• Article: CELL REPORTS. 2021;34(11):108852

  Virological and immunological features of SARS-CoV-2-infected children who develop neutralizing antibodies

  Cotugno N; Ruggiero A; Bonfante F; Petrara MR; Zicari S; Pascucci GR; Zangari P; De Ioris MA; Santilli V; Manno EC; Amodio D; Bortolami A; Pagliari M; Concato C; Linardos G; Campana A; Dona D; Giaquinto C; Brodin P; Rossi P; De Rossi A; Palma P
• Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2021;51(2):262-272

  Multimorbidity in asthma, association with allergy, inflammatory markers and symptom burden, results from the Swedish GA²LEN study

  Blondal V; Malinovschi A; Sundbom F; James A; Middelveld R; Franklin KA; Lundback B; Janson C
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2021;80(2):194-202

  Natural killer cells and type II interferon in Ro/SSA and La/SSB autoantibody-exposed newborns at risk of congenital heart block

  Ivanchenko M; Thorlacius GE; Hedlund M; Ottosson V; Meneghel L; Bjorkander S; Ossoinak A; Tingstrom J; Bremme K; Sverremark-Ekstrom E; Gemzell-Danielsson K; Sonesson S-E; Chemin K; Wahren-Herlenius M
• Article: PEDIATRIC RESEARCH. 2021;89(3):604-612

  Dramatic changes in blood protein levels during the first week of life in extremely preterm infants

  Zhong W; Danielsson H; Tebani A; Karlsson MJ; Elfvin A; Hellgren G; Brusselaers N; Brodin P; Hellstrom A; Fagerberg L; Uhlen M
• Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2021;110(2):641-642

  YKL-40 is a proposed biomarker of inflammation and remodelling elevated in children with bronchopulmonary dysplasia compared to asthma

  James AJ; Nordlund B; Konradsen JR; Ebersjo C; Dahlen S-E; Berggren Brostrom E; Hedlin G
• Article: CHILDREN. 2021;8(2):80

  A Novel Association between YKL-40, a Marker of Structural Lung Disease, and Short Telomere Length in 10-Year-Old Children with Bronchopulmonary Dysplasia

  Henckel E; James A; Konradsen JR; Nordlund B; Kjellberg M; Berggren-Brostrom E; Hedlin G; Degerman S; Bohlin K
• Article: IMMUNITY AND AGEING. 2021;18(1):5

  Aging and CMV discordance are associated with increased immune diversity between monozygotic twins

  Yan Z; Maecker HT; Brodin P; Nygaard UC; Lyu SC; Davis MM; Nadeau KC; Andorf S
• Article: FRONTIERS IN IMMUNOLOGY. 2021;12:727300

  High Dimensional Immune Profiling Reveals Different Response Patterns in Active and Latent Tuberculosis Following Stimulation With Mycobacterial Glycolipids

  Silva CS; Sundling C; Folkesson E; Froberg G; Nobrega C; Canto-Gomes J; Chambers BJ; Lakshmikanth T; Brodin P; Bruchfeld J; Nigou J; Correia-Neves M; Kallenius G
• Article: NATURE MEDICINE. 2021;27(1):28-33

  Immune determinants of COVID-19 disease presentation and severity

  Brodin P
• Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2021;203(1):37-53

  Urinary Leukotriene E₄ and Prostaglandin D₂ Metabolites Increase in Adult and Childhood Severe Asthma Characterized by Type 2 Inflammation A Clinical Observational Study

  Kolmert J; Gomez C; Balgoma D; Sjodin M; Bood J; Konradsen JR; Ericsson M; Thorngren J-O; James A; Mikus M; Sousa AR; Riley JH; Bates S; Bakke PS; Pandis I; Caruso M; Chanez P; Fowler SJ; Geiser T; Howarth P; Horvath I; Krug N; Montuschi P; Sanak M; Behndig A; Shaw DE; Knowles RG; Holweg CTJ; Wheelock AM; Dahlen B; Nordlund B; Alving K; Hedlin G; Chung KF; Adcock IM; Sterk PJ; Djukanovic R; Dahlen S-E; Wheelock CE
• Other: MOLECULAR MEDICINE. 2020;26(1):131

  High systemic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome (Retraction of Vol 20, Pg 538, 2014)

  Palmblad K; Schierbeck H; Sundberg E; Horne A-C; Harris HE; Henter J-I; Antoine DJ; Andersson U
• Article: MED. 2020;1(1):14-20

  Life-Threatening COVID-19: Defective Interferons Unleash Excessive Inflammation.

  Zhang Q; Bastard P; Bolze A; Jouanguy E; Zhang S-Y; COVID Human Genetic Effort; Cobat A; Notarangelo LD; Su HC; Abel L; Casanova J-L
• Article: SCIENTIFIC REPORTS. 2020;10(1):20425

  High CD45 expression of CD8+and CD4+T cells correlates with the size of HIV-1 reservoir in blood

  Petkov S; Bekele Y; Lakshmikanth T; Hejdeman B; Zazzi M; Brodin P; Chiodi F
• Article: CELL. 2020;183(4):968-981.e7

  The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19

  Consiglio CR; Cotugno N; Sardh F; Pou C; Amodio D; Rodriguez L; Tan Z; Zicari S; Ruggiero A; Pascucci GR; Santilli V; Campbell T; Bryceson Y; Eriksson D; Wang J; Marchesi A; Lakshmikanth T; Campana A; Villani A; Rossi P; Landegren N; Palma P; Brodin P
• Preprint: BIORXIV. 2020

  Bifidobacteria-mediated immune system imprinting early in life

  Henrick B; Rodriguez L; Lakshmikanth T; Pou C; Henckel E; Olin A; Wang J; Mikes J; Tan Z; Chen Y; Ehrlich A; Bernhardsson AK; Mugabo CH; Ambrosiani Y; Gustafsson A; Chew S; Brown H; Prambs J; Bohlin K; Mitchell R; Underwood M; Smilowitz J; German B; Frese S; Brodin P
• Article: SCIENCE. 2020;370(6515):eabd4585

  Autoantibodies against type I IFNs in patients with life-threatening COVID-19

  Bastard P; Rosen LB; Zhang Q; Michailidis E; Hoffmann H-H; Zhang Y; Dorgham K; Philippot Q; Rosain J; Beziat V; Manry J; Shaw E; Haljasmagi L; Peterson P; Lorenzo L; Bizien L; Trouillet-Assant S; Dobbs K; de Jesus AA; Belot A; Kallaste A; Catherinot E; Tandjaoui-Lambiotte Y; Le Pen J; Kerner G; Bigio B; Seeleuthner Y; Yang R; Bolze A; Spaan AN; Delmonte OM; Abers MS; Aiuti A; Casari G; Lampasona V; Piemonti L; Ciceri F; Bilguvar K; Lifton RP; Vasse M; Smadja DM; Migaud M; Hadjadj J; Terrier B; Duffy D; Quintana-Murci L; van de Beek D; Roussel L; Vinh DC; Tangye SG; Haerynck F; Dalmau D; Martinez-Picado J; Brodin P; Nussenzweig MC; Boisson-Dupuis S; Rodriguez-Gallego C; Vogt G; Mogensen TH; Oler AJ; Gu J; Burbelo PD; Cohen JI; Biondi A; Bettini LR; D'Angio M; Bonfanti P; Rossignol P; Mayaux J; Rieux-Laucat F; Husebye ES; Fusco F; Ursini MV; Imberti L; Sottini A; Paghera S; Quiros-Roldan E; Rossi C; Castagnoli R; Montagna D; Licari A; Marseglia GL; Duval X; Ghosn J; Tsang JS; Goldbach-Mansky R; Kisand K; Lionakis MS; Puel A; Zhang S-Y; Holland SM; Gorochov G; Jouanguy E; Rice CM; Cobat A; Notarangelo LD; Abel L; Su HC; Casanova J-L
• Article: ELIFE. 2020;9:e59996

  Cytotoxic T-cells mediate exercise-induced reductions in tumor growth

  Rundqvist H; Velica P; Barbieri L; Gameiro PA; Bargiela D; Gojkovic M; Mijwel S; Reitzner SM; Wulliman D; Ahlstedt E; Ule J; Ostman A; Johnson RS
• Article: SCIENCE. 2020;370(6515):eabd4570

  Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

  Zhang Q; Bastard P; Liu Z; Le Pen J; Moncada-Velez M; Chen J; Ogishi M; Sabli IKD; Hodeib S; Korol C; Rosain J; Bilguvar K; Ye J; Bolze A; Bigio B; Yang R; Arias AA; Zhou Q; Zhang Y; Onodi F; Korniotis S; Karpf L; Philippot Q; Chbihi M; Bonnet-Madin L; Dorgham K; Smith N; Schneider WM; Razooky BS; Hoffmann H-H; Michailidis E; Moens L; Han JE; Lorenzo L; Bizien L; Meade P; Neehus A-L; Ugurbil AC; Corneau A; Kerner G; Zhang P; Rapaport F; Seeleuthner Y; Manry J; Masson C; Schmitt Y; Schlueter A; Le Voyer T; Khan T; Li J; Fellay J; Roussel L; Shahrooei M; Alosaimi MF; Mansouri D; Al-Saud H; Al-Mulla F; Almourfi F; Al-Muhsen SZ; Alsohime F; Al Turki S; Hasanato R; van de Beek D; Biondi A; Bettini LR; D'Angio M; Bonfanti P; Imberti L; Sottini A; Paghera S; Quiros-Roldan E; Rossi C; Oler AJ; Tompkins MF; Alba C; Vandernoot I; Goffard J-C; Smits G; Migeotte I; Haerynck F; Soler-Palacin P; Martin-Nalda A; Colobran R; Morange P-E; Keles S; Colkesen F; Ozcelik T; Yasar KK; Senoglu S; Karabela SN; Rodriguez-Gallego C; Novelli G; Hraiech S; Tandjaoui-Lambiotte Y; Duval X; Laouenan C; Snow AL; Dalgard CL; Milner JD; Vinh DC; Mogensen TH; Marr N; Spaan AN; Boisson B; Boisson-Dupuis S; Bustamante J; Puel A; Ciancanelli MJ; Meyts I; Maniatis T; Soumelis V; Amara A; Nussenzweig M; Garcia-Sastre A; Krammer F; Pujol A; Duffy D; Lifton RP; Zhang S-Y; Gorochov G; Beziat V; Jouanguy E; Sancho-Shimizu V; Rice CM; Abel L; Notarangelo LD; Cobat A; Su HC; Casanova J-L
• Editorial comment: JOURNAL OF CLINICAL IMMUNOLOGY. 2020;40(7):958-959

  Unraveling the Immune Response in Severe COVID-19

  Rodriguez L; Brodin P
• Article: NATURE COMMUNICATIONS. 2020;11(1):4487

  Integration of molecular profiles in a longitudinal wellness profiling cohort

  Tebani A; Gummesson A; Zhong W; Koistinen IS; Lakshmikanth T; Olsson LM; Boulund F; Neiman M; Stenlund H; Hellstrom C; Karlsson MJ; Arif M; Dodig-Crnkovic T; Mardinoglu A; Lee S; Zhang C; Chen Y; Olin A; Mikes J; Danielsson H; von Feilitzen K; Jansson P-A; Angeras O; Huss M; Kjellqvist S; Odeberg J; Edfors F; Tremaroli V; Forsstrom B; Schwenk JM; Nilsson P; Moritz T; Backhed F; Engstrand L; Brodin P; Bergstrom G; Uhlen M; Fagerberg L
• Article: CELL REPORTS MEDICINE. 2020;1(5):100078

  Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19

  Rodriguez L; Pekkarinen PT; Lakshmikanth T; Tan Z; Consiglio CR; Pou C; Chen Y; Mugabo CH; Nguyen NA; Nowlan K; Strandin T; Levanov L; Mikes J; Wang J; Kantele A; Hepojoki J; Vapalahti O; Heinonen S; Kekalainen E; Brodin P
• Thesis / dissertation: 2020

  Exercise-induced molecular mechanisms in untrained and life-long highly trained individuals

  Reitzner, Stefan Markus
• Article: BLOOD ADVANCES. 2020;4(15):3754-3766

  Stem cell transplantation for children with hemophagocytic lymphohistiocytosis: results from the HLH-2004 study

  Bergsten E; Horne A; Myrberg IH; Arico M; Astigarraga I; Ishii E; Janka G; Ladisch S; Lehmberg K; McClain KL; Minkov M; Nanduri V; Rosso DA; Sieni E; Winiarski J; Henter J-I
• Editorial comment: CURRENT OPINION IN IMMUNOLOGY. 2020;65:iv

  Editorial overview: Evolutionary and systems immunology - methods to understand human immune system variation.

  Brodin P; Quintana-Murci L
• Review: CURRENT OPINION IN IMMUNOLOGY. 2020;65:28-31

  Technologies for assessing vaccine responses in the very young

  Brodin P
• Article: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2020;52(8):1679-1690

  Exercise Induces Different Molecular Responses in Trained and Untrained Human Muscle

  Moberg M; Lindholm ME; Reitzner SM; Ekblom B; Sundberg C-J; Psilander N
• Preprint: BIORXIV. 2020

  Single-cell classification using learned cell phenotypes

  Chen Y; Lakshmikanth T; Mikes J; Brodin P
• Article: CELL REPORTS. 2020;32(3):107923

  Human Immune System Variation during 1 Year

  Lakshmikanth T; Muhammad SA; Olin A; Chen Y; Mikes J; Fagerberg L; Gummesson A; Bergstrom G; Uhlen M; Brodin P
• Article: RHEUMATOLOGY. 2020;59(7):1651-1661

  Viral antigens elicit augmented immune responses in primary Sjogren's syndrome

  Bjork A; Thorlacius GE; Mofors J; Andersson ER; Ivanchenko M; Tingstrom J; James T; Brokstad KA; Cox RJ; Jonsson R; Kvarnstrom M; Wahren-Herlenius M
• Article: CELL REPORTS. 2020;31(12):107808

  Skeletal Muscle Transcriptomic Comparison between Long-Term Trained and Untrained Men and Women

  Chapman MA; Arif M; Emanuelsson EB; Reitzner SM; Lindholm ME; Mardinoglu A; Sundberg CJ
• Editorial comment: CELL. 2020;181(6):1194-1199

  A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection.

  Casanova J-L; Su HC; COVID Human Genetic Effort
• Article: LAKARTIDNINGEN. 2020;117:20094

  [Severe inflammation in children - cause for awareness during the current pandemic].

  Horne A; Nordenhäll L
• Review: HUMAN GENETICS. 2020;139(6-7):795-799

  New approaches to the study of immune responses in humans

  Brodin P
• Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2020;109(6):1082-1083

  Why is COVID-19 so mild in children?

  Brodin P
• Article: PEDIATRIC BLOOD AND CANCER. 2020;67(4):e28184

  Diagnostic challenges for a novel SH2D1A mutation associated with X-linked lymphoproliferative disease

  Torralba-Raga L; Tesi B; Chiang SCC; Schlums H; Nordenskjoeld M; Horne A; Henter J-I; Meeths M; Abdelhaleem M; Weitzman S; Bryceson Y
• Editorial comment: CELL. 2020;180(5):820-821

  Stressful Beginnings with Long-Term Consequences

  Consiglio CR; Brodin P
• Article: GENOME MEDICINE. 2020;12(1):25

  Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.

  Merid SK; Novoloaca A; Sharp GC; Küpers LK; Kho AT; Roy R; Gao L; Annesi-Maesano I; Jain P; Plusquin M; Kogevinas M; Allard C; Vehmeijer FO; Kazmi N; Salas LA; Rezwan FI; Zhang H; Sebert S; Czamara D; Rifas-Shiman SL; Melton PE; Lawlor DA; Pershagen G; Breton CV; Huen K; Baiz N; Gagliardi L; Nawrot TS; Corpeleijn E; Perron P; Duijts L; Nohr EA; Bustamante M; Ewart SL; Karmaus W; Zhao S; Page CM; Herceg Z; Jarvelin M-R; Lahti J; Baccarelli AA; Anderson D; Kachroo P; Relton CL; Bergström A; Eskenazi B; Soomro MH; Vineis P; Snieder H; Bouchard L; Jaddoe VW; Sørensen TIA; Vrijheid M; Arshad SH; Holloway JW; Håberg SE; Magnus P; Dwyer T; Binder EB; DeMeo DL; Vonk JM; Newnham J; Tantisira KG; Kull I; Wiemels JL; Heude B; Sunyer J; Nystad W; Munthe-Kaas MC; Räikkönen K; Oken E; Huang R-C; Weiss ST; Antó JM; Bousquet J; Kumar A; Söderhäll C; Almqvist C; Cardenas A; Gruzieva O; Xu C-J; Reese SE; Kere J; Brodin P; Solomon O; Wielscher M; Holland N; Ghantous A; Hivert M-F; Felix JF; Koppelman GH; London SJ; Melén E
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;145(3):808-817.e2

  IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways

  Manson ML; Safholm J; James A; Johnsson A-K; Bergman P; Al-Ameri M; Orre A-C; Karrman-Mardh C; Dahlen S-E; Adner M
• Other: MOLECULAR MEDICINE. 2020;26(1):17

  High systematic levels of the cytokine-inducing HMGB1 isoform secreted in severe macrophage activation syndrome (Expression of Concern of Vol 20, Pg 538, 2014)

  Palmblad K; Schierbeck H; Sundberg E; Horne A-C; Harris HE; Henter J-I; Antoine DJ; Andersson U
• Review: CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY. 2020;20(1):71-79

  Systemic and breath biomarkers for asthma: an update

  Mogensen I; James A; Malinovschi A
• Article: RMD OPEN. 2020;6(1):e000989

  Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero

  Hedlund M; Thorlacius GE; Ivanchenko M; Ottosson V; Kyriakidis N; Lagnefeldt L; Tingstrom J; Sirsjo A; Bengtsson AA; Aronsson E; Gemzell-Danielsson K; Ronnblom L; Bergman G; Espinosa A; Sonesson S-E; Eloranta M-L; Wahren-Herlenius M
• Article: SCIENCE. 2019;366(6472):eaax9198

  A genome-wide transcriptomic analysis of protein-coding genes in human blood cells

  Uhlen M; Karlsson MJ; Zhong W; Tebani A; Pou C; Mikes J; Lakshmikanth T; Forsstrom B; Edfors F; Odeberg J; Mardinoglu A; Zhang C; von Feilitzen K; Mulder J; Sjostedt E; Hober A; Oksvold P; Zwahlen M; Ponten F; Lindskog C; Sivertsson A; Fagerberg L; Brodin P
• Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2019;216(12):2778-2799

  A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function

  Lam MT; Coppola S; Krumbach OHF; Prencipe G; Insalaco A; Cifaldi C; Brigida I; Zara E; Scala S; Di Cesare S; Martinelli S; Di Rocco M; Pascarella A; Niceta M; Pantaleoni F; Ciolfi A; Netter P; Carisey AF; Diehl M; Akbarzadeh M; Conti F; Merli P; Pastore A; Mortera SL; Camerini S; Farina L; Buchholzer M; Pannone L; Cao TN; Coban-Akdemir ZH; Jhangiani SN; Muzny DM; Gibbs RA; Basso-Ricci L; Chiriaco M; Dvorsky R; Putignani L; Carsetti R; Janning P; Stray-Pedersen A; Erichsen HC; Horne A; Bryceson YT; Torralba-Raga L; Ramme K; Rosti V; Bracaglia C; Messia V; Palma P; Finocchi A; Locatelli F; Chinn IK; Lupski JR; Mace EM; Cancrini C; Aiuti A; Ahmadian MR; Orange JS; De Benedetti F; Tartaglia M
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(12):1621-1631

  Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts

  Sun M; Rethi B; Krishnamurthy A; Joshua V; Circiumaru A; Hensvold AH; Ossipova E; Gronwall C; Liu Y; Engstrom M; Catrina SB; Steen J; Malmstrom V; Klareskog L; Svensson C; Ospelt C; Wahamaa H; Catrina AI
• Review: JAMA PEDIATRICS. 2019;173(11):1032-1040

  Association of Use of the Neonatal Early-Onset Sepsis Calculator With Reduction in Antibiotic Therapy and Safety A Systematic Review and Meta-analysis

  Achten NB; Klingenberg C; Benitz WE; Stocker M; Schlapbach LJ; Giannoni E; Bokelaar R; Driessen GJA; Brodin P; Uthaya S; van Rossum AMC; Plotz FB
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(5):1198-1213

  IL-17-high asthma with features of a psoriasis immunophenotype

  Oestling J; van Geest M; Schofield JPR; Jevnikar Z; Wilson S; Ward J; Lutter R; Shaw DE; Bakke PS; Caruso M; Dahlen S-E; Fowler SJ; Horvath I; Krug N; Montuschi P; Sanak M; Sandstrom T; Sun K; Pandis I; Auffray C; Sousa AR; Guo Y; Adcock IM; Howarth P; Chung KF; Bigler J; Sterk PJ; Skipp PJ; Djukanovic R; Vaarala O; Ahmed H; Auffray C; Bakke P; Bansal AT; Baribaud F; Bates S; Bel EH; Bigler J; Bisgaard H; Boedigheimer MJ; Bonnelykke K; Brandsma J; Brinkman P; Bucchioni E; Burg D; Bush A; Caruso M; Chaiboonchoe A; Chanez P; Chung KF; Compton CH; Corfield J; D'Amico A; Dahlen SE; De Meulder B; Djukanovic R; Erpenbeck VJ; Erzen D; Fichtner K; Fitch N; Fleming LJ; Formaggio E; Fowler SJ; Frey U; Gahlemann M; Geiser T; Guo Y; Hashimoto S; Haughney J; Hedlin G; Hekking PW; Higenbottam T; Hohlfeld JM; Holweg C; Horvath I; Howarth P; James AJ; Knowles R; Knox AJ; Krug N; Lefaudeux D; Loza MJ; Lutter R; Manta A; Masefield S; Matthews JG; Mazein A; Meiser A; Middelveld RJM; Miralpeix M; Montuschi P; Mores N; Murray CS; Musial J; Myles D; Pahus L; Pandis I; Pavlidis S; Powell P; Pratico G; Valls MP; Rao N; Riley J; Roberts A; Roberts G; Rowe A; Sandstrom T; Seibold W; Selby A; Shaw DE; Sigmund R; Singer F; Skipp PJ; Sousa AR; Sterk PJ; Sun K; Thornton B; van Aalderen WM; van Geest M; Vestbo J; Vissing NH; Wagener AH; Wagers SS; Weiszhart Z; Wheelock CE; Wilson SJ
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(10):1357-1362

  Development and initial validation of the MS score for diagnosis of macrophage activation syndrome in systemic juvenile idiopathic arthritis

  Minoia F; Bovis F; Davi S; Horne A; Fischbach M; Frosch M; Huber A; Jelusic M; Sawhney S; McCurdy DK; Silva CA; Rigante D; Unsal E; Ruperto N; Martini A; Cron RQ; Ravelli A
• Article: PLOS BIOLOGY. 2019;17(10):e3000383

  Cell generation dynamics underlying naive T-cell homeostasis in adult humans

  Mold JE; Reu P; Olin A; Bernard S; Michaelsson J; Rane S; Yates A; Khosravi A; Salehpour M; Possnert G; Brodin P; Frisen J
• Article: JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY. 2019;29(8):625-633

  Establishing a Pediatric Acute-Onset Neuropsychiatric Syndrome Clinic: Baseline Clinical Features of the Pediatric Acute-Onset Neuropsychiatric Syndrome Cohort at Karolinska Institutet

  Gromark C; Harris RA; Wickstrom R; Horne A; Silverberg-Morse M; Serlachius E; Mataix-Cols D
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;144(1):70-82

  Stratification of asthma phenotypes by airway proteomic signatures

  Schofield JPR; Burg D; Nicholas B; Strazzeri F; Brandsma J; Staykova D; Folisi C; Bansal AT; Xian Y; Guo Y; Rowe A; Corfield J; Wilson S; Ward J; Lutter R; Shaw DE; Bakke PS; Caruso M; Dahlen S-E; Fowler SJ; Horvath I; Howarth P; Krug N; Montuschi P; Sanak M; Sandstrom T; Sun K; Pandis I; Riley J; Auffray C; De Meulder B; Lefaudeux D; Sousa AR; Adcock IM; Chung KF; Sterk PJ; Skipp PJ; Djukanovic R; Ahmed H; Allen D; Badorrek P; Ballereau S; Baribaud F; Batuwitage MK; Bedding A; Behndig AF; Berglind A; Berton A; Bigler J; Boedigheimer MJ; Bonnelykke K; Brinkman P; Bush A; Campagna D; Casaulta C; Chaiboonchoe A; Davison T; De Meulder B; Delin I; Dennison P; Dodson P; El Hadjam L; Erzen D; Faulenbach C; Fichtner K; Fitch N; Formaggio E; Gahlemann M; Galffy G; Garissi D; Garret T; Gent J; Guillmant-Farry E; Henriksson E; Hoda U; Hohlfeld JM; Hu X; James A; Johnson K; Jullian N; Kerry G; Klueglich M; Knowles R; Konradsen JR; Kretsos K; Krueger L; Lantz A-S; Larminie C; Latzin P; Lefaudeux D; Lemonnier N; Lowe LA; Lutter R; Manta A; Mazein A; McEvoy L; Menzies-Gow A; Mores N; Murray CS; Nething K; Nihlen U; Niven R; Nordlund B; Nsubuga S; Pellet J; Pison C; Pratico G; Puig Valls M; Riemann K; Rocha JP; Rossios C; Santini G; Saqi M; Scott S; Sehgal N; Selby A; Soderman P; Sogbesan A; Spycher F; Stephan S; Stokholm J; Sunther M; Szentkereszty M; Tamasi L; Tariq K; Valente S; van Aalderen WM; van Drunen CM; Van Eyll J; Vyas A; Yu W; Zetterquist W; Zolkipli Z; Zwinderman AH; Adriaens N; Aliprantis A; Alving K; Bakke P; Balgoma D; Barber C; Baribaud F; Bates S; Bautmans A; Beleta J; Bochenek G; Brandsma J; Braun A; Burg D; Carayannopoulos L; Rocha JPCDP; Chaleckis R; D'Amico A; De Alba J; De Lepeleire I; Dekker T; Dijkhuis A; Draper A; Edwards J; Emma R; Ericsson M; Flood B; Gallart H; Gomez C; Gove K; Gozzard N; Haughney J; Hewitt L; Hohlfeld J; Holweg C; Hu R; Hu S; Kamphuis J; Kennington EJ; Kerry D; Knobel H; Kolmert J; Kots M; Kuo S; Kupczyk M; Lambrecht B; Lone-Latif S; Loza MJ; Marouzet L; Martin J; Masefield S; Mathon C; Meah S; Meiser A; Metcalf L; Mikus M; Miralpeix M; Monk P; Naz S; Nicholas B; Nilsson P; Ostling J; Pacino A; Palkonen S; Pavlidis S; Pennazza G; Petren A; Pink S; Postle A; Powell P; Rahman-Amin M; Rao N; Ravanetti L; Ray E; Reinke S; Reynolds L; Riley J; Robberechts M; Roberts A; Russell K; Rutgers M; Santoninco M; Schoelch C; Schofield JPR; Sjodin M; Skipp PJ; Smids B; Smith C; Smith J; Smith KM; Staykova D; Sun K; Thorngren J-O; Thornton B; Thorsen J; van de Pol M; van Geest M; Versnel J; Vink A; Wald F; Walker S; Ward J; Weiszhart Z; Wetzel K; Wheelock CE; Wiegman C; Williams S; Wilson SJ; Woodcock A; Yang X; Yeyasingham E; Prins J-B; Gahlemann M; Visintin L; Evans H; Puhl M; Buzermaniene L; Hudson V; Bond L; de Boer P; Widdershoven G; Sigmund R; Roberts A; Supple D; Hamerlijnck D; Negus J; Kamphuis J; Sergison L; Visintin L; de Boer P; Onstein S; MacNee W; Bernardini R; Bont L; Wecksell P-A; de Boer P; Gahlemann M; Sigmund R
• Editorial comment: NATURE MEDICINE. 2019;25(7):1026

  Seeking the ultimate challenge

  Brodin P
• Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2019;108(7):1357-1358

  Leucocytosis is associated with retinopathy of prematurity in extremely preterm infants

  Lundgren P; Klevebro S; Brodin P; Smith LEH; Hallberg B; Hellstrom A
• Article: ELIFE. 2019;8:e43578

  Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'

  Landegren N; Rosen LB; Freyhult E; Eriksson D; Fall T; Smith G; Ferre EMN; Brodin P; Sharon D; Snyder M; Lionakis M; Anderson M; Kampe O
• Letter: IMMUNITY. 2019;50(6):1335-1336

  A Call for Blood-In Human Immunology

  Brodin P; Duffy D; Quintana-Murci L
• Article: BLOOD. 2019;133(23):2465-2477

  Recommendations for the management of hemophagocytic lymphohistiocytosis in adults

  La Rosee P; Horne A; Hines M; Greenwood TVB; Machowicz R; Berliner N; Birndt S; Gil-Herrera J; Girschikofsky M; Jordan MB; Kumar A; van Laar JAM; Lachmann G; Nichols KE; Ramanan AV; Wang Y; Wang Z; Janka G; Henter J-I
• Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2019;190:44-53

  Modulation of exercise training related adaptation of body composition and regulatory pathways by anabolic steroids

  Reitzner SM; Hengevoss J; Isenmann E; Diel P
• Article: JOURNAL OF IMMUNOLOGY. 2019;202(11):3143-3150

  Citrullination Controls Dendritic Cell Transdifferentiation into Osteoclasts

  Krishnamurthy A; Ytterberg AJ; Sun M; Sakuraba K; Steen J; Joshua V; Tarasova NK; Malmstrom V; Wahamaa H; Rethi B; Catrina AI
• Letter: EUROPEAN RESPIRATORY JOURNAL. 2019;53(6):1900453

  Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

  Perotin J-M; Schofield JPR; Wilson SJ; Ward J; Brandsma J; Strazzeri F; Bansal A; Yang X; Rowe A; Corfield J; Lutter R; Shaw DE; Bakke PS; Caruso M; Dahlen B; Fowler SJ; Horvath I; Howarth P; Krug N; Montuschi P; Sanak M; Sandstrom T; Sun K; Pandis I; Auffray C; De Meulder B; Lefaudeux D; Riley JH; Sousa AR; Dahlen S-E; Adcock IM; Chung KF; Sterk PJ; Skipp PJ; Collins JE; Davies DE; Djukanovic R; Adcock IM; Ahmed H; Auffray C; Bakke P; Banssal AT; Baribaud F; Bates S; Bel EH; Bigler J; Bisgaard H; Boedigheimer MJ; Bonnelykke K; Brandsma J; Brinkman P; Bucchioni E; Burg D; Bush A; Caruso M; Chaiboonchoe A; Chanez P; Chung KF; Compton CH; Corfield J; D'Amico A; Dahlen SE; De Meulder B; Djukanovic R; Erpenbeck VJ; Erzen D; Fichtner K; Fitch N; Fleming LJ; Formaggio E; Fowler SJ; Frey U; Gahlemann M; Geiser T; Guo Y; Hashimoto S; Haughney J; Hedlin G; Hekking PW; Higenbottam T; Hohlfeld JM; Holweg C; Horvath I; Howarth P; James AJ; Knowles R; Knox AJ; Krug N; Lefaudeux D; Loza MJ; Lutter R; Manta A; Masefield S; Matthews JG; Mazein A; Meiser A; Middelveld RJM; Miralpeix M; Montuschi P; Mores N; Murray CS; Musial J; Myles D; Pahus L; Pandis I; Pavlidis S; Powell P; Pratico G; Puig Valls M; Rao N; Riley J; Roberts A; Roberts G; Rowe A; Sandstrom T; Seibold W; Selby A; Shaw DE; Sigmund R; Singer F; Skipp PJ; Sousa AR; Sterk PJ; Sun K; Thornton B; van Aalderen WM; van Geest M; Vestbo J; Vissing NH; Wagener AH; Wagers SS; Weiszhart Z; Wheelock CE; Wilson SJ; Aliprantis A; Allen D; Alving K; Badorrek P; Balgoma D; Ballereau S; Barber C; Batuwitage MK; Bautmans A; Bedding A; Behndig AF; Beleta J; Berglind A; Berton A; Bochenek G; Braun A; Campagna D; Carayannopoulos L; Casaulta C; Chaleckis R; Dahlen B; Davison T; De Alba J; De Lepeleire I; Dekker T; Delin I; Dennison P; Dijkhuis A; Dodson P; Dyson K; Edwards J; El Hadjam L; Emma R; Ericsson M; Faulenbach C; Flood B; Galffy G; Gallart H; Garissi D; Gent J; de Verdier MG; Gibeon D; Gomez C; Gove K; Guillmant-Farry E; Henriksson E; Hewitt L; Hoda U; Hu R; Hu S; Hu X; Jeyasingham E; Johnson K; Jullian N; Kamphuis J; Kennington EJ; Kerry D; Kerry G; Klueglich M; Knobel H; Kolmert J; Konradsen JR; Kots M; Kretsos K; Krueger L; Kuo S; Kupczyk M; Lambrecht B; Lantz A-S; Larminie C; Larsson LX; Latzin P; Lazarinis N; Lemonnier N; Lone-Latif S; Lowe LA; Manta A; Marouzet L; Martin J; Mathon C; McEvoy L; Meah S; Menzies-Gow A; Metcalf L; Mikus M; Monk P; Naz S; Nething K; Nicholas B; Nihlen U; Nilsson P; Niven R; Nordlund B; Nsubuga S; Ostling J; Pacino A; Palkonen S; Pellet J; Pennazza G; Petren A; Pink S; Pison C; Postle A; Rahman-Amin M; Ravanetti L; Ray E; Reinke S; Reynolds L; Riemann K; Robberechts M; Rocha JP; Rossios C; Russell K; Rutgers M; Santini G; Santoninco M; Saqi M; Schoelch C; Schofield JPR; Scott S; Sehgal N; Sjodin M; Smids B; Smith C; Smith J; Smith KM; Soderman P; Sogbessan A; Spycher F; Staykova D; Stephan S; Stokholm J; Strandberg K; Sunther M; Szentkereszty M; Tamasi L; Tariq K; Thorngren J-O; Thorsen J; Valente S; van de Pol M; van Drunen CM; Van Eyll J; Versnel J; Vink A; von Garnier C; Vyas A; Wald F; Walker S; Ward J; Wetzel K; Wiegman C; Williams S; Yang X; Yeyasingham E; Yu W; Zetterquist W; Zolkipli Z; Zwinderman AH; Prins J-B; Gahlemann M; Visintin L; Evans H; Puhl M; Buzermaniene L; Hudson V; Bond L; de Boer P; Widdershoven G; Sigmund R; Roberts A; Supple D; Hamerlijnck D; Negus J; Kamphuis J; Sergison L; Visintin L; de Boer P; Onstein S; MacNee W; Bernardini R; Bont L; Wecksell P-A; de Boer P; Gahlemann M; Sigmund R; Draper A; Gozzard N
• Thesis / dissertation: 2019

  Cellular and molecular factors in the pathogenesis of systemic autoimmunity and comorbidities

  Ivanchenko, Margarita
• Article: JCI INSIGHT. 2019;4(9):126492

  B cell profiling in malaria reveals expansion and remodeling of CD11c⁺ B cell subsets

  Sundling C; Ronnberg C; Yman V; Asghar M; Jahnmatz P; Lakshmikanth T; Chen Y; Mikes J; Forsell MN; Sonden K; Achour A; Brodin P; Persson KEM; Farnert A
• Article: NATURE MEDICINE. 2019;25(4):591-596

  The repertoire of maternal anti-viral antibodies in human newborns

  Pou C; Nkulikiyimfura D; Henckel E; Olin A; Lakshmikanth T; Mikes J; Wang J; Chen Y; Bernhardsson AK; Gustafsson A; Bohlin K; Brodin P
• Review: THE FEBS JOURNAL. 2019;286(8):1514-1522

  The biology of the cell - insights from mass cytometry

  Brodin P
• Letter: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2019;195(3):305-309

  FoxP3⁺CXCR5⁺CD4⁺ T cell frequencies are increased in peripheral blood of patients with primary Sjogren's syndrome

  Ivanchenko M; Aqrawi LA; Bjork A; Wahren-Herlenius M; Chemin K
• Article: JCI INSIGHT. 2019;4(3):e125442

  Mass cytometry identifies distinct CD4⁺ T cell clusters distinguishing HIV-1-infected patients according to antiretroviral therapy initiation

  Bekele Y; Lakshmikanth T; Chen Y; Mikes J; Nasi A; Petkov S; Hejdeman B; Brodin P; Chiodi F
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(2):577-590

  Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

  Jevnikar Z; Ostling J; Calven J; Thorn K; Israelsson E; Oberg L; Singhania A; Lau LCK; Wilson SJ; Ward JA; Chauhan A; Sousa AR; De Meulder B; Loza MJ; Baribaud F; Sterk PJ; Chung KF; Sun K; Guo Y; Adcock IM; Payne D; Dahlen B; Chanez P; Shaw DE; Krug N; Hohlfeld JM; Sandstrom T; Djukanovic R; James A; Hinks TSC; Howarth PH; Vaarala O; van Geest M; Olsson H
• Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2019;49(2):155-162

  Fixed airflow obstruction relates to eosinophil activation in asthmatics

  Mogensen I; Alving K; Dahlen S-E; James A; Forsberg B; Ono J; Ohta S; Venge P; Borres MP; Izuhara K; Janson C; Malinovschi A
• Editorial comment: NATURE REVIEWS IMMUNOLOGY. 2019;19(2):87-88

  Systems-level patterns emerge

  Brodin P
• Article: EBIOMEDICINE. 2019;40:517-527

  B cell alterations during BAFF inhibition with belimumab in SLE

  Ramskold D; Parodis I; Lakshmikanth T; Sippl N; Khademi M; Chen Y; Zickert A; Mikes J; Achour A; Amara K; Piehl F; Brodin P; Gunnarsson I; Malmstrom V
• Letter: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;74(2):406-411

  Treatable traits in the European U-BIOPRED adult asthma cohorts

  Simpson AJ; Hekking P-P; Shaw DE; Fleming LJ; Roberts G; Riley JH; Bates S; Sousa AR; Bansal AT; Pandis I; Sun K; Bakke PS; Caruso M; Dahlen B; Dahlen S-E; Horvath I; Krug N; Montuschi P; Sandstrom T; Singer F; Adcock IM; Wagers SS; Djukanovic R; Chung KF; Sterk PJ; Fowler SJ; Adcock IM; Ahmed H; Auffray C; Bakke P; Bansal AT; Baribaud F; Bates S; Bel EH; Bigler J; Bisgaard H; Boedigheimer MJ; Bonnelykke K; Brandsma J; Brinkman P; Bucchioni E; Burg D; Bush A; Caruso M; Chaiboonchoe A; Chanez P; Chung FK; Compton CH; Corfield J; D'Amico A; Dahlen B; Dahlen SE; De Meulder B; Djukanovic R; Erpenbeck VJ; Erzen D; Fichtner K; Fitch N; Fleming LJ; Formaggio E; Fowler SJ; Frey U; Gahlemann M; Geiser T; Goss V; Guo Y; Hashimoto S; Haughney J; Hedlin G; Hekking PW; Higenbottam T; Hohlfeld JM; Holweg C; Horvath I; Howarth P; James AJ; Knowles R; Knox AJ; Krug N; Lefaudeux D; Loza MJ; Lutter R; Manta A; Masefield S; Matthews JG; Mazein A; Meiser A; Middelveld RJM; Miralpeix M; Montuschi P; Mores N; Murray CS; Musial J; Myles D; Pahus L; Pandis I; Pavlidis S; Postle A; Powel P; Pratico G; Puig Valls M; Rao N; Riley J; Roberts A; Roberts G; Rowe A; Sandstrom T; Schofield JPR; Seibold W; Selby A; Shaw DE; Sigmund R; Singer F; Skipp PJ; Sousa AR; Sterk PJ; Sun K; van Aalderen WM; van Geest M; Vestbo J; Vissing NH; Wagener AH; Wagers SS; Weiszhart Z; Wheelock CE; Wilson SJ
• Article: METHODS IN MOLECULAR BIOLOGY. 2019;1989:111-123

  Automated Cell Processing for Mass Cytometry Experiments.

  Mikes J; Olin A; Lakshmikanth T; Chen Y; Brodin P
• Article: METHODS IN MOLECULAR BIOLOGY. 2019;1913:33-48

  Systems-Level Immune Monitoring by Mass Cytometry.

  Lakshmikanth T; Brodin P
• Article: RMD OPEN. 2019;5(2):e001055

  Juvenile idiopathic arthritis and risk of cancer before and after the introduction of biological therapies

  Horne A; Delcoigne B; Palmblad K; Askling J
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2019;89(1):e12732

  Effect of CTLA4-Ig (abatacept) treatment on T cells and B cells in peripheral blood of patients with polymyositis and dermatomyositis

  Tang Q; Ramskold D; Krystufkova O; Mann HF; Wick C; Dastmalchi M; Lakshmikanth T; Chen Y; Mikes J; Alexanderson H; Achour A; Brodin P; Vencovsky J; Lundberg IE; Malmstrom V
• Article: ARTHRITIS RESEARCH & THERAPY. 2018;20(1):285

  Pharmacovigilance in juvenile idiopathic arthritis patients treated with biologic or synthetic drugs: combined data of more than 15,000 patients from Pharmachild and national registries

  Swart J; Giancane G; Horneff G; Magnusson B; Hofer M; Alexeeva E; Panaviene V; Bader-Meunier B; Anton J; Nielsen S; De Benedetti F; Kamphuis S; Stanevica V; Tracahana M; Ailioaie LM; Tsitsami E; Klein A; Minden K; Foeldvari I; Haas JP; Klotsche J; Horne AC; Consolaro A; Bovis F; Bagnasco F; Pistorio A; Martini A; Wulffraat N; Ruperto N
• Letter: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(12):1840-1842

  Clinical associations and expression pattern of the autoimmunity susceptibility factor DIORA-1 in patients with primary Sjogren's syndrome

  Aqrawi LA; Mentlein L; Meneghel L; Bjork A; Thorlacius GE; Ivanchenko M; Sepulveda JIR; Skarstein K; Kvarnstrom M; Brauner S; Espinosa A; Wahren-Herlenius M
• Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2018;194(3):315-326

  The Sjogren's syndrome-associated autoantigen Ro52/TRIM21 modulates follicular B cell homeostasis and immunoglobulin production

  Brauner S; Ivanchenko M; Thorlacius GE; Ambrosi A; Wahren-Herlenius M
• Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2018;48(9):1147-1154

  IgE sensitization to food allergens and airborne allergens in relation to biomarkers of type 2 inflammation in asthma

  Patelis A; Alving K; Middelveld R; James A; Ono J; Ohta S; Izuhara K; Borres MP; Forsberg B; Janson C; Malinovschi A
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY: IN PRACTICE. 2018;6(5):1508-1517

  Recommendations for the Use of Etoposide-Based Therapy and Bone Marrow Transplantation for the Treatment of HLH: Consensus Statements by the HLH Steering Committee of the Histiocyte Society

  Ehl S; Astigarraga I; Greenwood TVB; Hines M; Horne A; Ishii E; Janka G; Jordan MB; La Rosee P; Lehmberg K; Machowicz R; Nichols KE; Sieni E; Wang Z; Henter J-I
• Article: CELL. 2018;174(5):1277-1292.e14

  Stereotypic Immune System Development in Newborn Children

  Olin A; Henckel E; Chen Y; Lakshmikanth T; Pou C; Mikes J; Gustafsson A; Bernhardsson AK; Zhang C; Bohlin K; Brodin P
• Article: CLINICAL IMMUNOLOGY. 2018;193:70-79

  Plasmablast antibody repertoires in elderly influenza vaccine responders exhibit restricted diversity but increased breadth of binding across influenza strains

  Ju C-H; Blum LK; Kongpachith S; Lingampalli N; Mao R; Brodin P; Dekker CL; Davis MM; Robinson WH
• Article: ERJ OPEN RESEARCH. 2018;4(3):33-2018

  Altered Fc galactosylation in IgG4 is a potential serum marker for chronic lung disease

  Heyder T; Wiklundh E; Eklund A; James A; Dahlen S-E; Grunewald J; Zubarev RA; Lundström SL
• Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2018;192(3):259-270

  Diminished CXCR5 expression in peripheral blood of patients with Sjogren's syndrome may relate to both genotype and salivary gland homing

  Aqrawi LA; Ivanchenko M; Bjork A; Sepulveda JIR; Imgenberg-Kreuz J; Kvarnstrom M; Haselmayer P; Jensen JL; Nordmark G; Chemin K; Skarstein K; Wahren-Herlenius M
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2018;50(5S):845

  Expression Of Markers Of Browning In White Adipose Tissue In Life-long Endurance Trained Athletes

  Reitzner SM; Kissling S; Chapman M; Sundberg CJ
• Review: ANNUAL REVIEW OF IMMUNOLOGY. 2018;36:843-864

  Rebooting Human Immunology

  Davis MM; Brodin P
• Letter: CLINICAL AND EXPERIMENTAL ALLERGY. 2018;48(4):475-478

  IL-6 pathway upregulation in subgroup of severe asthma is associated with neutrophilia and poor lung function

  Turan N; Edwards MJ; Bates S; Shaw D; Chung KF; Loza MJ; James A; Van Oosterhout A
• Article: PHYSIOLOGICAL REPORTS. 2018;6(5):e13624

  Expression of striated activator of rho-signaling in human skeletal muscle following acute exercise and long-term training

  Reitzner SM; Norrbom J; Sundberg CJ; Gidlund E-K
• Article: CELL METABOLISM. 2018;27(2):378-392.e5

  Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation

  Agudelo LZ; Ferreira DMS; Cervenka I; Bryzgalova G; Dadvar S; Jannig PR; Pettersson-Klein AT; Lakshmikanth T; Sustarsic EG; Porsmyr-Palmertz M; Correia JC; Izadi M; Martinez-Redondo V; Ueland PM; Midttun O; Gerhart-Hines Z; Brodin P; Pereira T; Berggren P-O; Ruas JL
• Article: SCIENTIFIC REPORTS. 2018;8(1):28

  Discovering viral genomes in human metagenomic data by predicting unknown protein families

  Barrientos-Somarribas M; Messina DN; Pou C; Lysholm F; Bjerkner A; Allander T; Andersson B; Sonnhammer ELL
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2018;50(5):845

  Expression Of Markers Of Browning In White Adipose Tissue In Life-long Endurance Trained Athletes

  Reitzner SM; Kissling S; Chapman M; Sundberg CJ
• Article: FRONTIERS IN MOLECULAR BIOSCIENCES. 2018;5:81

  Continuous Immune Cell Differentiation Inferred From Single-Cell Measurements Following Allogeneic Stem Cell Transplantation

  Chen Y; Lakshmikanth T; Olin A; Mikes J; Remberger M; Brodin P
• Article: BLOOD. 2017;130(25):2728-2738

  Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study

  Bergsten E; Horne A; Arico M; Astigarraga I; Egeler RM; Filipovich AH; Ishii E; Janka G; Ladisch S; Lehmberg K; McClain KL; Minkov M; Montgomery S; Nanduri V; Rosso D; Henter J-I
• Article: SCIENTIFIC REPORTS. 2017;7(1):16327

  STRT-seq-2i: dual-index 5′ single cell and nucleus RNA-seq on an addressable microwell array

  Hochgerner H; Lonnerberg P; Hodge R; Mikes J; Heskol A; Hubschle H; Lin P; Picelli S; La Manno G; Ratz M; Dunne J; Husain S; Lein E; Srinivasan M; Zeisel A; Linnarsson S
• Article: JOURNAL OF AUTOIMMUNITY. 2017;84:29-45

  Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis

  Gronwall C; Amara K; Hardt U; Krishnamurthy A; Steen J; Engstrom M; Sun M; Ytterberg AJ; Zubarev RA; Scheel-Toellner D; Greenberg JD; Klareskog L; Catrina AI; Malmstrom V; Silverman GJ
• Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;72(11):1753-1760

  Serum periostin relates to type-2 inflammation and lung function in asthma: Data from the large population-based cohort Swedish GA(2)LEN

  James A; Janson C; Malinovschi A; Holweg C; Alving K; Ono J; Ohta S; Ek A; Middelveld R; Dahlen B; Forsberg B; Izuhara K; Dahlen S-E
• Article: JOURNAL OF PEDIATRICS. 2017;189:72-78.e3

  Development and Initial Validation of the Macrophage Activation Syndrome/Primary Hemophagocytic Lymphohistiocytosis Score, a Diagnostic Tool that Differentiates Primary Hemophagocytic Lymphohistiocytosis from Macrophage Activation Syndrome

  Minoia F; Bovis F; Davi S; Insalaco A; Lehmberg K; Shenoi S; Weitzman S; Espada G; Gao Y-J; Anton J; Kitoh T; Kasapcopur O; Sanner H; Merino R; Astigarraga I; Alessio M; Jeng M; Chasnyk V; Nichols KE; Zeng H; Li C; Micalizzi C; Ruperto N; Martini A; Cron RQ; Ravelli A; Horne A
• Article: PEDIATRIC PULMONOLOGY. 2017;52(9):1179-1186

  Differences and similarities between bronchopulmonary dysplasia and asthma in schoolchildren

  Nordlund B; James A; Ebersjo C; Hedlin G; Brostrom EB
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(3):135-142

  The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education

  Ganesan S; Luu TT; Chambers BJ; Meinke S; Brodin P; Vivier E; Wetzel DM; Koleske AJ; Kadri N; Hoglund P
• Article: JOURNAL OF ORAL AND FACIAL PAIN AND HEADACHE. 2017;31(4):353-361

  Parenting a Child with Juvenile Idiopathic Arthritis, Orofacial Pain, and Dysfunction: A Qualitative Study

  Leksell E; Hallberg U; Horne A; Ernberg M; Hedenberg-Magnusson B
• Article: CELL REPORTS. 2017;20(9):2238-2250

  Mass Cytometry and Topological Data Analysis Reveal Immune Parameters Associated with Complications after Allogeneic Stem Cell Transplantation

  Lakshmikanth T; Olin A; Chen Y; Mikes J; Fredlund E; Remberger M; Omazic B; Brodin P
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2017;114(30):E6097-E6106

  Continuous immunotypes describe human immune variation and predict diverse responses

  Kaczorowski KJ; Shekhar K; Nkulikiyimfura D; Dekker CL; Maecker H; Davis MM; Chakraborty AK; Brodin P
• Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2017;47(7):909-917

  Assessment of in vivo mast cell reactivity in patients with systemic mastocytosis

  Gulen T; Westerberg CM; Lyberg K; Ekoff M; Kolmert J; Bood J; Ohd J; James A; Dahlen S-E; Nilsson G; Dahlen B
• Article: NATURE COMMUNICATIONS. 2017;8:15627

  Expression of CD226 is associated to but not required for NK cell education

  Wagner AK; Kadri N; Snall J; Brodin P; Gilfillan S; Colonna M; Bernhardt GN; Hoglund P; Karre K; Chambers BJ
• Conference publication: MEDICINE & SCIENCE IN SPORTS & EXERCISE. 2017;49(5S):1087

  Acute Exercise Increases STARS mRNA in Human Skeletal Muscle

  Reitzner S; Gidlund E-K; Sundberg CJ
• Article: SCIENTIFIC REPORTS. 2017;7:43989

  Immunogenicity is preferentially induced in sparse dendritic cell cultures

  Nasi A; Bollampalli VP; Sun M; Chen Y; Amu S; Nylen S; Eidsmo L; Rothfuchs AG; Rethi B
• Editorial comment: CELL HOST AND MICROBE. 2017;21(3):309-310

  Life-Saving Degeneracy in the Human Immune System

  Brodin P
• Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2017;28(1):79-85

  A longitudinal assessment of circulating YKL-40 levels in preschool children with wheeze

  James A; Hammar KS; Reinius L; Konradsen JR; Dahlen S-E; Soderhall C; Hedlin G
• Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1130

  Mass Cytometry Identifies Distinct Lung CD4⁺ T Cell Patterns in Lofgren's Syndrome and Non-Lofgren's Syndrome Sarcoidosis

  Kaiser Y; Lakshmikanth T; Chen Y; Mikes J; Eklund A; Brodin P; Achour A; Grunewald J
• Review: NATURE REVIEWS IMMUNOLOGY. 2017;17(1):21-29

  Human immune system variation

  Brodin P; Davis MM
• Review: CURRENT TREATMENT OPTIONS IN NEUROLOGY. 2017;19(1):3

  How to Treat Involvement of the Central Nervous System in Hemophagocytic Lymphohistiocytosis?

  Horne A; Wickstrom R; Jordan MB; Yeh EA; Naqvi A; Henter J-I; Janka G
• Article: FRONTIERS IN IMMUNOLOGY. 2017;8:717

  Combining Flow and Mass Cytometry in the Search for Biomarkers in Chronic Graft-versus-Host Disease

  Stikvoort A; Chen Y; Radestad E; Torlen J; Lakshmikanth T; Bjorklund A; Mikes J; Achour A; Gertow J; Sundberg B; Remberger M; Sundin M; Mattsson J; Brodin P; Uhlin M
• Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2016;71(12):1728-1735

  Rhinovirus-specific antibody responses in preschool children with acute wheeze reflect severity of respiratory symptoms

  Stenberg-Hammar K; Niespodziana K; Soederhaell C; James A; Cabauatan CR; Konradsen JR; Melen E; van Hage M; Valenta R; Hedlin G
• Article: BRITISH JOURNAL OF CANCER. 2016;115(8):1008-1014

  Virome characterisation from Guthrie cards in children who later developed acute lymphoblastic leukaemia

  Bogdanovic G; Pou C; Barrientos-Somarribas M; Bjerkner A; Honkaniemi E; Allander T; Andersson B; Gustafsson B
• Article: RETROVIROLOGY. 2016;13(1):51

  Lack of concordance between residual viremia and viral variants driving de novo infection of CD4⁺ T cells on ART

  Puertas MC; Noguera-Julian M; Massanella M; Pou C; Buzon MJ; Clotet B; Stevenson M; Paredes R; Blanco J; Martinez-Picado J
• Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2016;46(7):1758-1769

  In vivo engineering of mobilized stem cell grafts with the immunomodulatory drug FTY720 for allogeneic transplantation

  Lakshmikanth T; Heuts F; Muvva SSVJR; Wallin RPA; Persson A-K; Fauriat C; Applequist SE; Ljunggren H-G; Hoglund P; Karre K; Svensson M; Juarez JG
• Review: BLOOD. 2016;127(22):2672-2681

  Revised classification of histiocytoses and neoplasms of the macrophage-dendritic cell lineages

  Emile J-F; Abla O; Fraitag S; Horne A; Haroche J; Donadieu J; Requena-Caballero L; Jordan MB; Abdel-Wahab O; Allen CE; Charlotte F; Diamond EL; Egeler RM; Fischer A; Gil Herrera J; Henter J-I; Janku F; Merad M; Picarsic J; Rodriguez-Galindo C; Rollins BJ; Tazi A; Vassallo R; Weiss LM
• Review: NATURE REVIEWS. RHEUMATOLOGY. 2016;12(5):259-268

  Macrophage activation syndrome in the era of biologic therapy

  Grom AA; Horne A; De Benedetti F
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(4):721-729

  Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss

  Krishnamurthy A; Joshua V; Hensvold AH; Jin T; Sun M; Vivar N; Ytterberg AJ; Engstrom M; Fernandes-Cerqueira C; Amara K; Magnusson M; Wigerblad G; Kato J; Jimenez-Andrade JM; Tyson K; Rapecki S; Lundberg K; Catrina S-B; Jakobsson P-J; Svensson C; Malmstrom V; Klareskog L; Wahamaa H; Catrina AI
• Review: TRENDS IN IMMUNOLOGY. 2016;37(3):233-243

  Immune Adaptation to Environmental Influence: The Case of NK Cells and HCMV

  Roelle A; Brodin P
• Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(3):481-489

  2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative

  Ravelli A; Minoia F; Davi S; Horne A; Bovis F; Pistorio A; Arico M; Avcin T; Behrens EM; De Benedetti F; Filipovic L; Grom AA; Henter J-I; Ilowite NT; Jordan MB; Khubchandani R; Kitoh T; Lehmberg K; Lovell DJ; Miettunen P; Nichols KE; Ozen S; Schmid JP; Ramanan AV; Russo R; Schneider R; Sterba G; Uziel Y; Wallace C; Wouters C; Wulffraat N; Demirkaya E; Brunner HI; Martini A; Ruperto N; Cron RQ
• Article: ARTHRITIS & RHEUMATOLOGY. 2016;68(3):566-576

  2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative

  Ravelli A; Minoia F; Davi S; Horne A; Bovis F; Pistorio A; Arico M; Avcin T; Behrens EM; De Benedetti F; Filipovic L; Grom AA; Henter J-I; Ilowite NT; Jordan MB; Khubchandani R; Kitoh T; Lehmberg K; Lovell DJ; Miettunen P; Nichols KE; Ozen S; Schmid JP; Ramanan AV; Russo R; Schneider R; Sterba G; Uziel Y; Wallace C; Wouters C; Wulffraat N; Demirkaya E; Brunner HI; Martini A; Ruperto N; Cron RQ
• Article: CANCER IMMUNOLOGY RESEARCH. 2016;4(2):113-123

  Retuning of Mouse NK Cells after Interference with MHC Class I Sensing Adjusts Self-Tolerance but Preserves Anticancer Response

  Wagner AK; Wickstrom SL; Tallerico R; Salam S; Lakshmikanth T; Brauner H; Hoglund P; Carbone E; Johansson MH; Karre K
• Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2016;193(2):131-142

  Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease

  James AJ; Reinius LE; Verhoek M; Gomes A; Kupczyk M; Hammar U; Ono J; Ohta S; Izuhara K; Bel E; Kere J; Soderhall C; Dahlen B; Boot RG; Dahlen S-E
• Article: RMD OPEN. 2016;2(1):e000161

  Expert consensus on dynamics of laboratory tests for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

  Ravelli A; Minoia F; Davì S; Horne A; Bovis F; Pistorio A; Aricò M; Avcin T; Behrens EM; De Benedetti F; Filipovic A; Grom AA; Henter J-I; Ilowite NT; Jordan MB; Khubchandani R; Kitoh T; Lehmberg K; Lovell DJ; Miettunen P; Nichols KE; Ozen S; Pachlopnik Schmid J; Ramanan AV; Russo R; Schneider R; Sterba G; Uziel Y; Wallace C; Wouters C; Wulffraat N; Demirkaya E; Brunner HI; Martini A; Ruperto N; Cron RQ
• Review: CURRENT TREATMENT OPTIONS IN ALLERGY. 2016;3(4):439-452

  Biomarkers for the Phenotyping and Monitoring of Asthma in Children.

  James A; Hedlin G
• Article: PLOS ONE. 2016;11(1):e0146687

  A Follow-Up of the Multicenter Collaborative Study on HIV-1 Drug Resistance and Tropism Testing Using 454 Ultra Deep Pyrosequencing.

  St John EP; Simen BB; Turenchalk GS; Braverman MS; Abbate I; Aerssens J; Bouchez O; Gabriel C; Izopet J; Meixenberger K; Di Giallonardo F; Schlapbach R; Paredes R; Sakwa J; Schmitz-Agheguian GG; Thielen A; Victor M; Metzner KJ; Däumer MP; 454 HIV-1 Alpha Study Group
• Editorial comment: IMMUNITY. 2015;43(6):1035-1037

  Powerful Populations Respond to Viruses and Vaccines

  Brodin P
• Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2015;26(8):772-779

  Predicting asthma morbidity in children using proposed markers of Th2-type inflammation

  Konradsen JR; Skantz E; Nordlund B; Lidegran M; James A; Ono J; Ohta S; Izuhara K; Dahlen S-E; Alving K; Hedlin G
• Article: HAEMATOLOGICA. 2015;100(11):1477-1485

  Risks and benefits of sex-mismatched hematopoietic cell transplantation differ according to conditioning strategy

  Nakasone H; Remberger M; Tian L; Brodin P; Sahaf B; Wu F; Mattsson J; Lowsky R; Negrin R; Miklos DB; Meyer E
• Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2015;70(10):2885-2888

  Primary resistance to integrase strand-transfer inhibitors in Europe.

  Casadellà M; van Ham PM; Noguera-Julian M; van Kessel A; Pou C; Hofstra LM; Santos JR; Garcia F; Struck D; Alexiev I; Bakken Kran AM; Hoepelman AI; Kostrikis LG; Somogyi S; Liitsola K; Linka M; Nielsen C; Otelea D; Paraskevis D; Poljak M; Puchhammer-Stöckl E; Staneková D; Stanojevic M; Van Laethem K; Zidovec Lepej S; Clotet B; Boucher CAB; Paredes R; Wensing AMJ; SPREAD programme
• Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2015;70(9):2639-2647

  Determinants of virological failure and antiretroviral drug resistance in Mozambique.

  Rupérez M; Pou C; Maculuve S; Cedeño S; Luis L; Rodríguez J; Letang E; Moltó J; Macete E; Clotet B; Alonso P; Menéndez C; Naniche D; Paredes R
• Article: JOURNAL OF INTERNAL MEDICINE. 2015;278(3):323-332

  Reduced expression of TRIM21/Ro52 predicts poor prognosis in diffuse large B-cell lymphoma patients with and without rheumatic disease

  Brauner S; Zhou W; Backlin C; Green TM; Folkersen L; Ivanchenko M; Lofstrom B; Xu-Monette ZY; Young KH; Pedersen LM; Moller MB; Sundstrom C; Enblad G; Baecklund E; Wahren-Herlenius M
• Article: PROSTAGLANDINS AND OTHER LIPID MEDIATORS. 2015;121(Pt A):83-90

  On the biosynthesis of 15-HETE and eoxin C₄ by human airway epithelial cells

  Brunnstrom A; Tryselius Y; Feltenmark S; Andersson E; Leksell H; James A; Mannervik B; Dahlen B; Claesson H-E
• Article: AIDS. 2015;29(12):1493-1504

  Clinical value of ultradeep HIV-1 genotyping and tropism testing in late presenters with advanced disease.

  Casadellà M; Manzardo C; Noguera-Julian M; Ferrer E; Domingo P; Pérez-Álvarez S; Podzamczer D; Plana M; Clotet B; Gatell JM; Miró JM; Paredes R; ADVANZ and ADVANZ-3 Investigators
• Article: JOURNAL OF RHEUMATOLOGY. 2015;42(6):994-1001

  Dissecting the Heterogeneity of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis

  Minoia F; Davi S; Horne A; Bovis F; Demirkaya E; Akikusa J; Ayaz NA; Al-Mayouf SM; Barone P; Bica B; Bolt I; Breda L; De Cunto C; Enciso S; Gallizzi R; Griffin T; Hennon T; Horneff G; Jeng M; Kapovic AM; Lipton JM; Manzoni SM; Rumba-Rozenfelde I; Magalhaes CS; Sewairi WM; Stine KC; Vougiouka O; Weaver LK; Davidsone Z; De Inocencio J; Ioseliani M; Lattanzi B; Tezer H; Buoncompagni A; Picco P; Ruperto N; Martini A; Cron RQ; Ravelli A
• Article: DIABETOLOGIA. 2015;58(2):346-354

  A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models

  Larsson PG; Lakshmikanth T; Laitinen OH; Utorova R; Jacobson S; Oikarinen M; Domsgen E; Koivunen MRL; Chaux P; Devard N; Lecouturier V; Almond J; Knip M; Hyoty H; Flodstrom-Tullberg M
• Article: PEDIATRIC BLOOD AND CANCER. 2015;62(2):346-352

  Incidence and Clinical Presentation of Primary Hemophagocytic Lymphohistiocytosis in Sweden

  Meeths M; Horne A; Sabel M; Bryceson YT; Henter J-I
• Article: CELL. 2015;160(1-2):37-47

  Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

  Brodin P; Jojic V; Gao T; Bhattacharya S; Angel CJL; Furman D; Shen-Orr S; Dekker CL; Swan GE; Butte AJ; Maecker HT; Davis MM
• Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(11):3160-3169

  Clinical Features, Treatment, and Outcome of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis A Multinational, Multicenter Study of 362 Patients

  Minoia F; Davi S; Horne A; Demirkaya E; Bovis F; Li C; Lehmberg K; Weitzman S; Insalaco A; Wouters C; Shenoi S; Espada G; Ozen S; Anton J; Khubchandani R; Russo R; Pal P; Kasapcopur O; Miettunen P; Maritsi D; Merino R; Shakoory B; Alessio M; Chasnyk V; Sanner H; Gao Y-J; Zeng H; Kitoh T; Avcin T; Fischbach M; Frosch M; Grom A; Huber A; Jelusic M; Sawhney S; Uziel Y; Ruperto N; Martini A; Cron RQ; Ravelli A
• Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2014;740:302-311

  Bitter taste receptor agonists mediate relaxation of human and rodent vascular smooth muscle

  Manson ML; Safholm J; Al-Ameri M; Bergman P; Orre A-C; Sward K; James A; Dahlen S-E; Adner M
• Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(10):2871-2880

  Performance of Current Guidelines for Diagnosis of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis

  Davi S; Minoia F; Pistorio A; Horne A; Consolaro A; Rosina S; Bovis F; Cimaz R; Gamir ML; Ilowite NT; Kone-Paut I; Feitosa de Oliveira SK; McCurdy D; Silva CA; Sztajnbok F; Tsitsami E; Unsal E; Weiss JE; Wulffraat N; Abinun M; Aggarwal A; Apaz MT; Astigarraga I; Corona F; Cuttica R; D'Angelo G; Eisenstein EM; Hashad S; Lepore L; Mulaosmanovic V; Nielsen S; Prahalad S; Rigante D; Stanevicha V; Sterba G; Susic G; Takei S; Trauzeddel R; Zletni M; Ruperto N; Martini A; Cron RQ; Ravelli A
• Article: CLINICAL INFECTIOUS DISEASES. 2014;59(4):578-588

  Improved prediction of salvage antiretroviral therapy outcomes using ultrasensitive HIV-1 drug resistance testing.

  Pou C; Noguera-Julian M; Pérez-Álvarez S; García F; Delgado R; Dalmau D; Álvarez-Tejado M; Gonzalez D; Sayada C; Chueca N; Pulido F; Ibáñez L; Rodríguez C; Casadellà M; Santos JR; Ruiz L; Clotet B; Paredes R
• Article: JOURNAL OF VIROLOGICAL METHODS. 2014;204:31-37

  An international multicenter study on HIV-1 drug resistance testing by 454 ultra-deep pyrosequencing.

  Simen BB; Braverman MS; Abbate I; Aerssens J; Bidet Y; Bouchez O; Gabriel C; Izopet J; Kessler HH; Stelzl E; Di Giallonardo F; Schlapbach R; Radonic A; Paredes R; Recordon-Pinson P; Sakwa J; St John EP; Schmitz-Agheguian GG; Metzner KJ; Däumer MP; 454 HIV Alphastudy Group
• Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(2):475-478

  Bitter taste receptor (TAS2R) agonists inhibit IgE-dependent mast cell activation

  Ekoff M; Choi J-H; James A; Dahlen B; Nilsson G; Dahlen S-E
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2014;134(2):306-313

  Effects of selective COX-2 inhibition on allergen-induced bronchoconstriction and airway inflammation in asthma

  Daham K; James A; Balgoma D; Kupczyk M; Billing B; Lindeberg A; Henriksson E; FitzGerald GA; Wheelock CE; Dahlen S-E; Dahlen B
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(1):202-207

  Automatic Classification of Cellular Expression by Nonlinear Stochastic Embedding (ACCENSE)

  Shekhar K; Brodin P; Davis MM; Chakraborty AK
• Article: PLOS ONE. 2014;9(12):e111758

  Mechanical Stress Downregulates MHC Class I Expression on Human Cancer Cell Membrane

  La Rocca R; Tallerico R; Hassan AT; Das G; Tadepally L; Matteucci M; Liberale C; Mesuraca M; Scumaci D; Gentile F; Cojoc G; Perozziello G; Ammendolia A; Gallo A; Karre K; Cuda G; Candeloro P; Di Fabrizio E; Carbone E
• Article: PEPTIDES. 2014;51:100-109

  Enhanced expression of neuropeptide S (NPS) receptor in eosinophils from severe asthmatics and subjects with total IgE above 100 IU/ml

  Ilmarinen P; James A; Moilanen E; Pulkkinen V; Daham K; Saarelainen S; Laitinen T; Dahlen S-E; Kere J; Dahlen B; Kankaanranta H
• Article: VIROLOGY JOURNAL. 2013;10:350

  Stable HIV-1 integrase diversity during initial HIV-1 RNA decay suggests complete blockade of plasma HIV-1 replication by effective raltegravir-containing salvage therapy.

  Noguera-Julian M; Casadellà M; Pou C; Rodríguez C; Pérez-Álvarez S; Puig J; Clotet B; Paredes R
• Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2013;51(8):2754-2757

  RECall for automated genotypic tropism testing.

  Pou C; Bellido R; Casadellà M; Puig T; Clotet B; Harrigan R; Paredes R
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2013;132(2):328-35.e5

  The chitinase-like protein YKL-40: A possible biomarker of inflammation and airway remodeling in severe pediatric asthma

  Konradsen JR; James A; Nordlund B; Reinius LE; Soderhall C; Melen E; Wheelock A; Carlsen KCL; Lidegran M; Verhoek M; Boot RG; Dahlen B; Dahlen SE; Hedlin G
• Article: THORAX. 2013;68(7):611-618

  Detection of exacerbations in asthma based on electronic diary data: results from the 1-year prospective BIOAIR study

  Kupczyk M; Haque S; Sterk PJ; Nizankowska-Mogilnicka E; Papi A; Bel EH; Chanez P; Dahlen B; Gaga M; Gjomarkaj M; Howarth PH; Johnston SL; Joos GF; Kanniess F; Tzortzaki E; James A; Middelveld RJM; Dahlen S-E
• Article: EUROPEAN RESPIRATORY JOURNAL. 2013;42(1):65-78

  Transcriptome analysis reveals upregulation of bitter taste receptors in severe asthmatics

  Orsmark-Pietrast C; James A; Konradsen JR; Nordlund B; Soderhall C; Pulkkinen V; Pedroletti C; Daham K; Kupczyk M; Dahlen B; Kere J; Dahlen S-E; Hedlin G; Melen E
• Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2013;68(6):1382-1387

  Switching the third drug of antiretroviral therapy to maraviroc in aviraemic subjects: a pilot, prospective, randomized clinical trial.

  Bonjoch A; Pou C; Pérez-Álvarez N; Bellido R; Casadellà M; Puig J; Noguera-Julian M; Clotet B; Negredo E; Paredes R
• Article: RESPIRATORY RESEARCH. 2013;14(1):47

  Adhesion molecules in subjects with COPD and healthy non-smokers: a cross sectional parallel group study

  Blidberg K; Palmberg L; James A; Billing B; Henriksson E; Lantz A-S; Larsson K; Dahlen B
• Article: IMMUNOBIOLOGY. 2013;218(4):543-547

  HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Δ32/Δ32.

  Ballana E; Riveira-Munoz E; Pou C; Bach V; Parera M; Noguera M; Santos JR; Badia R; Casadellà M; Clotet B; Paredes R; Martínez MA; Brander C; Esté JA
• Article: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2013;9(4):307-317

  Systems level immune response analysis and personalized medicine

  Brodin P; Valentini D; Uhlin M; Mattsson J; Zumla A; Maeurer MJ
• Article: DIABETOLOGIA. 2013;56(4):867-874

  Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice

  Larsson PG; Lakshmikanth T; Svedin E; King C; Flodstrom-Tullberg M
• Article: TRAFFIC. 2013;14(2):205-218

  Multiple Sorting Systems for Secretory Granules Ensure the Regulated Secretion of Peptide Hormones

  Sun M; Watanabe T; Bochimoto H; Sakai Y; Torii S; Takeuchi T; Hosaka M
• Article: PLOS ONE. 2013;8(8):e67085

  HIV-1 tropism testing in subjects achieving undetectable HIV-1 RNA: diagnostic accuracy, viral evolution and compartmentalization.

  Pou C; Codoñer FM; Thielen A; Bellido R; Pérez-Álvarez S; Cabrera C; Dalmau J; Curriu M; Lie Y; Noguera-Julian M; Puig J; Martínez-Picado J; Blanco J; Coakley E; Däumer M; Clotet B; Paredes R
• Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2013;162(2):135-142

  The Influence of Aspirin on Release of Eoxin C4, Leukotriene C4 and 15-HETE, in Eosinophilic Granulocytes Isolated from Patients with Asthma

  James A; Daham K; Backman L; Brunnstrom A; Tingvall T; Kumlin M; Edenius C; Dahlen S-E; Dahlen B; Claesson H-E
• Article: FRONTIERS IN IMMUNOLOGY. 2013;4:65

  Natural killer cell inhibitory receptor expression in humans and mice: a closer look

  Sternberg-Simon M; Brodin P; Pickman Y; Onfelt B; Karre K; Malmberg K-J; Hoglund P; Mehr R
• Article: INTERNATIONAL JOURNAL OF HEMATOLOGY. 2012;96(6):798-800

  Major surgery in a neutropenic patient undergoing allogeneic stem cell transplantation for high risk myelofibrosis

  Brodin P; Gilg S; Lundell L; Mattsson J
• Editorial comment: ONCOIMMUNOLOGY. 2012;1(4):541-543

  A novel facet of tumor suppression by p53 Induction of tumor immunogenicity

  Li H; Lakshmikanth T; Carbone E; Selivanova G
• Article: ALLERGY. EUROPEAN JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2012;67(7):958-961

  Corticosteroid treatment selectively decreases mast cells in the smooth muscle and epithelium of asthmatic bronchi

  James A; Gyllfors P; Henriksson E; Dahlen SE; Adner M; Nilsson G; Dahlen B
• Article: ONCOGENESIS. 2012;1(3):e3

  MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma

  Sonkoly E; Loven J; Xu N; Meisgen F; Wei T; Brodin P; Jaks V; Kasper M; Shimokawa T; Harada M; Heilborn J; Hedblad M-A; Hippe A; Grander D; Homey B; Zaphiropoulos PG; Arsenian-Henriksson M; Stahle M; Pivarcsi A
• Article: JOURNAL OF IMMUNOLOGY. 2012;188(5):2218-2226

  Skewing of the NK Cell Repertoire by MHC Class I via Quantitatively Controlled Enrichment and Contraction of Specific Ly49 Subsets

  Brodin P; Lakshmikanth T; Karre K; Hoglund P
• Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2012;101(3):313-318

  Risk factors for early death in children with haemophagocytic lymphohistiocytosis

  Trottestam H; Berglof E; Horne A; Onelov E; Beutel K; Lehmberg K; Sieni E; Silfverberg T; Arico M; Janka G; Henter J-I
• Article: PLOS ONE. 2012;7(2):e32714

  In-depth characterization of viral isolates from plasma and cells compared with plasma circulating quasispecies in early HIV-1 infection.

  Dalmau J; Codoñer FM; Erkizia I; Pino M; Pou C; Paredes R; Clotet B; Martinez-Picado J; Prado JG
• Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2012;67(1):32-38

  A non-infectious cell-based phenotypic assay for the assessment of HIV-1 susceptibility to protease inhibitors.

  Buzon MJ; Erkizia I; Pou C; Minuesa G; Puertas MC; Esteve A; Castello A; Santos JR; Prado JG; Izquierdo-Useros N; Pattery T; Van Houtte M; Carrasco L; Clotet B; Ruiz L; Martinez-Picado J
• Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2012;158(3):299-306

  Challenge of Isolated Sputum Cells Supports in vivo Origin of Intolerance Reaction to Aspirin/Non-Steroidal Anti-Inflammatory Drugs in Asthma

  Higashi A; Kumlin M; Higashi N; Daham K; Gaber F; Lindeberg A; James A; Skedinger M; Delin I; Gyllfors P; Dahlen S-E; Dahlen B
• Thesis / dissertation: 2011

  MHC class I molecules in natural killer cell education and tolerance

  Brodin, Petter
• Article: BLOOD. 2011;118(17):4577-4584

  Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol

  Trottestam H; Horne A; Arico M; Egeler RM; Filipovich AH; Gadner H; Imashuku S; Ladisch S; Webb D; Janka G; Henter J-I
• Article: PLOS PATHOGENS. 2011;7(10):e1002314

  Deep molecular characterization of HIV-1 dynamics under suppressive HAART.

  Buzón MJ; Codoñer FM; Frost SDW; Pou C; Puertas MC; Massanella M; Dalmau J; Llibre JM; Stevenson M; Blanco J; Clotet B; Paredes R; Martinez-Picado J
• Article: CELL CYCLE. 2011;10(19):3346-3358

  Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2

  Li H; Lakshmikanth T; Garofalo C; Enge M; Spinnler C; Anichini A; Szekely L; Karre K; Carbone E; Selivanova G
• Article: JOURNAL OF INFECTIOUS DISEASES. 2011;204(5):741-752

  A376S in the connection subdomain of HIV-1 reverse transcriptase confers increased risk of virological failure to nevirapine therapy.

  Paredes R; Puertas MC; Bannister W; Kisic M; Cozzi-Lepri A; Pou C; Bellido R; Betancor G; Bogner J; Gargalianos P; Bánhegyi D; Clotet B; Lundgren J; Menéndez-Arias L; Martinez-Picado J; EuroSIDA Study Group
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2011;131(7):1521-1529

  MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2

  Xu N; Brodin P; Wei T; Meisgen F; Eidsmo L; Nagy N; Kemeny L; Stahle M; Sonkoly E; Pivarcsi A
• Article: PLOS ONE. 2011;6(5):e19461

  Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects.

  Codoñer FM; Pou C; Thielen A; García F; Delgado R; Dalmau D; Álvarez-Tejado M; Ruiz L; Clotet B; Paredes R
• Article: ANTIVIRAL RESEARCH. 2010;88(3):281-286

  Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure.

  Codoñer FM; Pou C; Thielen A; García F; Delgado R; Dalmau D; Santos JR; Buzón MJ; Martínez-Picado J; Alvarez-Tejado M; Clotet B; Ruiz L; Paredes R
• Article: PLOS ONE. 2010;5(10):e13174

  Natural Killer Cell Tolerance Persists Despite Significant Reduction of Self MHC Class I on Normal Target Cells in Mice

  Brodin P; Lakshmikanth T; Mehr R; Johansson MH; Duru AD; Achour A; Salmon-Divon M; Karre K; Hoglund P; Johansson S
• Review: NATURE REVIEWS IMMUNOLOGY. 2010;10(10):724-734

  Current perspectives of natural killer cell education by MHC class I molecules

  Hoeglund P; Brodin P
• Review: TRENDS IN IMMUNOLOGY. 2010;31(9):339-345

  New views on natural killer cell-based immunotherapy for melanoma treatment

  Burke S; Lakshmikanth T; Colucci F; Carbone E
• Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2010;40(3):813-823

  In vivo tumor cell rejection induced by NK cell inhibitory receptor blockade: Maintained tolerance to normal cells even in the presence of IL-2

  Vahlne G; Lindholm K; Meier A; Wickstrom S; Lakshmikanth T; Brennan F; Wilken M; Nielsen R; Romagne F; Wagtmann NR; Karre K; Johansson MH
• Article: JOURNAL OF BIOMEDICAL OPTICS. 2010;15(2):027007

  Monitoring human leukocyte antigen class I molecules by micro-Raman spectroscopy at single-cell level

  Das G; La Rocca R; Lakshmikanth T; Gentile F; Tallerico R; Zambetti LP; Devitt J; Candeloro P; De Angelis F; Carbone E; Di Fabrizio E
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(4):1553-1558

  MYCN-regulated microRNAs repress estrogen receptor-α (ESR1) expression and neuronal differentiation in human neuroblastoma

  Loven J; Zinin N; Wahlstrom T; Muller I; Brodin P; Fredlund E; Ribacke U; Pivarcsi A; Pahlman S; Henriksson M
• Article: JOURNAL OF NEUROSCIENCE. 2009;29(43):13503-13515

  Classical Major Histocompatibility Complex Class I Molecules in Motoneurons: New Actors at the Neuromuscular Junction

  Thams S; Brodin P; Plantman S; Saxelin R; Karre K; Cullheim S
• Article: PLOS ONE. 2009;4(6):e6046

  Probing Natural Killer Cell Education by Ly49 Receptor Expression Analysis and Computational Modelling in Single MHC Class I Mice

  Johansson S; Salmon-Divon M; Johansson MH; Pickman Y; Brodin P; Karre K; Mehr R; Hoglund P
• Thesis / dissertation: 2009

  Clinical and epidemiological studies of haemophagocytic lymphohistiocytosis

  Horne, AnnaCarin
• Article: JOURNAL OF CLINICAL INVESTIGATION. 2009;119(5):1251-1263

  NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

  Lakshmikanth T; Burke S; Ali TH; Kimpfler S; Ursini F; Ruggeri L; Capanni M; Umansky V; Paschen A; Sucker A; Pende D; Groh V; Biassoni R; Hoglund P; Kato M; Shibuya K; Schadendorf D; Anichini A; Ferrone S; Velardi A; Karre K; Shibuya A; Carbone E; Colucci F
• Article: JOURNAL OF IMMUNOLOGY. 2009;182(8):4529-4537

  Early Hematopoietic Zinc Finger Protein Prevents Tumor Cell Recognition by Natural Killer Cells

  La Rocca R; Fulciniti M; Lakshmikanth T; Mesuraca M; Ali TH; Mazzei V; Amodio N; Catalano L; Rotoli B; Ouerfelli O; Grieco M; Gulletta E; Bond HM; Morrone G; Ferrone S; Carbone E
• Review: TRENDS IN IMMUNOLOGY. 2009;30(4):143-149

  NK cell education: not an on-off switch but a tunable rheostat

  Brodin P; Karre K; Hoglund P
• Article: IMMUNITY. 2009;30(3):337-347

  A Role for cis Interaction between the Inhibitory Ly49A Receptor and MHIC Class I for Natural Killer Cell Education

  Chalifour A; Scarpellino L; Back J; Brodin P; Devevre E; Gros F; Levy F; Leclercq G; Hoglund P; Beermann F; Held W
• Article: BLOOD. 2009;113(11):2434-2441

  The strength of inhibitory input during education quantitatively tunes the functional responsiveness of individual natural killer cells

  Brodin P; Lakshmikanth T; Johansson S; Karre K; Hoglund P
• Article: JOURNAL OF MEDICAL GENETICS. 2009;46(3):159-167

  The protective effect of farm animal exposure on childhood allergy is modified by NPSR1 polymorphisms

  Bruce S; Nyberg F; Melen E; James A; Pulkkinen V; Orsmark-Pietras C; Bergstrom A; Dahlen B; Wickman M; von Mutius E; Doekes G; Lauener R; Riedler J; Eder W; van Hage M; Pershagen G; Scheynius A; Kere J
• Article: JOURNAL OF IMMUNOLOGY. 2009;182(3):1460-1468

  Distinct and Overlapping Patterns of Cytokine Regulation of Thymic and Bone Marrow-Derived NK Cell Development

  Cheng M; Charoudeh HN; Brodin P; Tang Y; Lakshmikanth T; Hoglund P; Jacobsen SEW; Sitnicka E
• Article: THORAX. 2008;63(12):1076-1082

  Increased levels of cysteinyl-leukotrienes in saliva, induced sputum, urine and blood from patients with aspirin-intolerant asthma

  Gaber F; Daham K; Higashi A; Higashi N; Gulich A; Delin I; James A; Skedinger M; Gyllfors P; Nord M; Dahlen S-E; Kumlin M; Dahlen B
• Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2008;38(11):2934-2937

  Beyond licensing and disarming: A quantitative view on NK-cell education

  Brodin P; Hoglund P
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;143(1):75-83

  Characterization of PRF1, STX11 and UNC13D genotype-phenotype correlations in familial hemophagocytic lymphohistiocytosis

  Horne A; Ramme KG; Rudd E; Zheng C; Wali Y; al-Lamki Z; Guergey A; Yalman N; Nordenskjold M; Henter J-I
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2008;140(3):327-335

  Frequency and spectrum of central nervous system involvement in 193 children with haemophagocytic lymphohistiocytosis

  Horne A; Trottestam H; Arico M; Egeler RM; Filipovich AH; Gadner H; Imashuku S; Ladisch S; Webb D; Janka G; Henter J-I
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(1):1-11

  IFN-γ production and degranulation are differentially regulated in response to stimulation in murine natural killer cells

  Vahlne G; Becker S; Brodin P; Johansson MH
• Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;67(1):30-36

  Critical role of Qa1^b in the protection of mature dendritic cells from NK cell-mediated killing

  Persson CM; Assarsson E; Vahlne G; Brodin P; Chambers BJ
• Published conference paper: MICROELECTRONIC ENGINEERING. 2007;84(5-8):1729-1732

  Preliminary study of micromechanical stress delivery for cell biology studies

  Matteucci M; Lakshmikanth T; Shibu K; De Angelis F; Schadendorf D; Venuta S; Carbone E; Di Fabrizio E
• Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2007;119(5):1267-1268

  Assessment of in vivo 5-lipoxygenase activity by analysis of leukotriene B₄ in saliva:: Effects of treatment with zileuton

  Gaber F; James A; Delin I; Wetterholm A; Sampson AP; Dahlen B; Dahlen S-E; Kumlin M
• Review: PEDIATRIC BLOOD AND CANCER. 2007;48(2):124-131

  HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis

  Henter J-I; Horne A; Arico M; Egeler RM; Filipovich AH; Imashuku S; Ladisch S; McClain K; Webb D; Winiarski J; Janka G
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2005;129(5):658-666

  Subtyping of natural killer cell cytotoxicity deficiencies in haemophagocytic lymphohistocytosis provides therapeutic guidance

  Horne A; Zheng CY; Lorenz I; Löfstedt M; Montgomery SM; Janka G; Henter JI; Schneider EM
• Article: BRITISH JOURNAL OF HAEMATOLOGY. 2005;129(5):622-630

  Haematopoietic stem cell transplantation in haemophagocytic lymphohistiocytosis

  Horne A; Janka G; Egeler RM; Gadner H; Imashuku S; Ladisch S; Locatelli F; Montgomery SM; Webb D; Winiarski J; Filipovich AH; Henter JI
• Article: NATIONAL ACADEMY SCIENCE LETTERS. 2005;28(9-10):353-355

  Detection of haemocyanin in native PAGE gels

  Krupanidhi S; Lakshmikanth T
• Article: BLOOD. 2002;100(7):2367-2373

  Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation

  Henter JI; Samuelsson-Horne A; Aricò M; Egeler RM; Elinder G; Filipovich AH; Gadner H; Imashuku S; Komp D; Ladisch S; Webb D; Janka G
• Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2001;68(3):590-597

  Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis

  Ericson KG; Fadeel B; Nilsson-Ardnor S; Söderhäll C; Samuelsson A; Janka G; Schneider M; Gürgey A; Yalman N; Révész T; Egeler RM; Jahnukainen K; Storm-Mathiesen I; Haraldsson A; Poole J; de Saint Basile G; Nordenskjöld M; Henter JI
• Review: LAKARTIDNINGEN. 2000;97(12):1405-1408

  [Familial hemophagocytic lymphohistiocytosis: diagnosis, treatment and pathophysiological mechanisms].

  Henter JI; Samuelsson A; Ericson K; Nilsson-Ardnor S; Elinder G; Fadeel B
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Staff and contact

Group leader

• 

  Petter Brodin

  Professor/Specialist Physician | Docent

  Telephone +46852481396

  E-mail petter.brodin@ki.se

All members of the group

• Aron Arzoomand

  Clinical Assistant | Phd Student

  E-mail aron.arzoomand@ki.se
• Hugo Barcenilla

  Research Specialist

  E-mail hugo.barcenilla@ki.se
• Anna Karin Bernhardsson

  Research Nurse

  E-mail anna.karin.bernhardsson@ki.se
• 

  Petter Brodin

  Professor/Specialist Physician | Docent

  Telephone +46852481396

  E-mail petter.brodin@ki.se
• Alexis Chasseur

  Postdoctoral Researcher

  E-mail alexis.chasseur@ki.se
• Qi Chen

  Clinical Assistant

  E-mail qi.chen.2@ki.se
• 

  Yang Chen

  Senior Research Specialist

  E-mail yang.chen@ki.se
• Rikard Forlin

  Phd Student | Clinical Assistant

  E-mail rikard.forlin@ki.se
• Laura Gonzalez

  Laboratory Technician

  E-mail laura.gonzalez@ki.se
• Annacarin Horne

  Affiliated to Research

  E-mail annacarin.horne@ki.se
• Rita Ivanchenko

  Postdoctoral Researcher

  E-mail rita.ivanchenko@ki.se
• Anna James

  Researcher

  Telephone +46852487514

  E-mail anna.james@ki.se
• Anette Johnsson

  Laboratory Technician

  E-mail anette.johnsson@ki.se
• Genia Kretzschmar

  Phd Student

  E-mail genia.kretzschmar@ki.se
• Florens Lohrmann

  Postdoctoral Studies

  E-mail florens.lohrmann@ki.se
• Aman Mebrahtu

  Affiliated to Research

  E-mail aman.mebrahtu@ki.se
• 

  Jaromir Mikes

  Senior Research Specialist

  Telephone +46852486945

  E-mail jaromir.mikes@ki.se
• Erika Negrini

  Laboratory Technician

  E-mail erika.negrini@ki.se
• 

  Stefan Reitzner

  Assistant Professor

  E-mail stefan.reitzner@ki.se
• Lucie Rodriguez

  Affiliated to Research

  E-mail lucie.rodriguez@ki.se
• 

  Meng Sun

  Research Specialist

  E-mail meng.sun@ki.se
• 

  Lakshmikanth Tadepally

  Senior Research Specialist

  Telephone +46852481231

  E-mail lakshmikanth.tadepally@ki.se
• Ziyang Tan

  Postdoctoral Researcher

  E-mail ziyang.tan@ki.se
• Joël Tekoniemi

  Laboratory Technician

  E-mail joel.tekoniemi@ki.se
• Jun Wang

  Senior Research Infrastructure Specialist

  E-mail jun.wang@ki.se
• 

  Binbin Zhao

  Phd Student

  E-mail binbin.zhao@ki.se