Utforskar olika cellsignaleringsfenomen och deras inverkan på kritiska biologiska och medicinska processer med avancerad ljusmikroskopi – Per Uhléns grupp

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Article: SCIENCE. 2024;386(6724):907-915
Whole-brain spatial transcriptional analysis at cellular resolution
Kanatani S; Kreutzmann JC; Li Y; West Z; Larsen LL; Nikou DV; Eidhof I; Walton A; Zhang S; Rodriguez-Kirby LR; Skytte JL; Salinas CG; Takamatsu K; Li X; Tanaka DH; Kaczynska D; Fukumoto K; Karamzadeh R; Xiang Y; Uesaka N; Tanabe T; Adner M; Hartman J; Miyakawa A; Sundstrom E; Castelo-Branco G; Roostalu U; Hecksher-Sorensen J; Uhlen P
Editorial comment: NATURE METHODS. 2022;19(5):527-529
Imaging cleared tissues made easy
Kanatani S; Uhlen P
Article: NATURE COMMUNICATIONS. 2022;13(1):1537
GIT1 protects against breast cancer growth through negative regulation of Notch
Zhang S; Miyakawa A; Wickstrom M; Dyberg C; Louhivuori L; Varas-Godoy M; Kemppainen K; Kanatani S; Kaczynska D; Ellstrom ID; Elfman L; Kronqvist P; Repo H; Mikoshiba K; Sahlgren C; Johnsen JI; Uhlen P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(7):e2108768119
Disrupted Cacna1c gene expression perturbs spontaneous Ca²⁺ activity causing abnormal brain development and increased anxiety
Smedler E; Louhivuori L; Romanov RA; Masini D; Ellstrom ID; Wang C; Caramia M; West Z; Zhang S; Rebellato P; Malmersjo S; Brusini I; Kanatani S; Fisone G; Harkany T; Uhlen P
Article: NATURE BIOMEDICAL ENGINEERING. 2020;4(9):875-888
Three-dimensional single-cell imaging for the analysis of RNA and protein expression in intact tumour biopsies
Tanaka N; Kanatani S; Kaczynska D; Fukumoto K; Louhivuori L; Mizutani T; Kopper O; Kronqvist P; Robertson S; Lindh C; Kis L; Pronk R; Niwa N; Matsumoto K; Oya M; Miyakawa A; Falk A; Hartman J; Sahlgren C; Clevers H; Uhlen P
Editorial comment: NATURE BIOMEDICAL ENGINEERING. 2018;2(10):717-718
Predicting a tumour's drug uptake
Louhivuori L; Kanatani S; Uhlen P
Editorial comment: TRENDS IN CANCER. 2018;4(5):337-341
Improved Pathological Examination of Tumors with 3D Light-Sheet Microscopy
Uhlen P; Tanaka N
Article: BRITISH JOURNAL OF CANCER. 2018;118(7):995-999
Mapping of the three-dimensional lymphatic microvasculature in bladder tumours using light-sheet microscopy
Tanaka N; Kaczynska D; Kanatani S; Sahlgren C; Mitura P; Stepulak A; Miyakawa A; Wiklund P; Uhlen P
Article: NATURE BIOMEDICAL ENGINEERING. 2017;1(10):796-806
Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity
Tanaka N; Kanatani S; Tomer R; Sahlgren C; Kronqvist P; Kaczynska D; Louhivuori L; Kis L; Lindh C; Mitura P; Stepulak A; Corvigno S; Hartman J; Micke P; Mezheyeuski A; Strell C; Carlson JW; Moro CF; Dahlstrand H; Ostman A; Matsumoto K; Wiklund P; Oya M; Miyakawa A; Deisseroth K; Uhlen P
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2014;1840(3):964-969
Frequency decoding of calcium oscillations
Smedler E; Uhlen P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(16):E1524-E1532
Neural progenitors organize in small-world networks to promote cell proliferation
Malmersjo S; Rebellato P; Smedler E; Planert H; Kanatani S; Liste I; Nanou E; Sunner H; Abdelhady S; Zhang S; Andang M; El Manira A; Silberberg G; Arenas E; Uhlen P
Journal article: SCIENCES STKE [ELECTRONIC RESOURCE] : SIGNAL TRANSDUCTION KNOWLEDGE ENVIRONMENT. 2004;2004(258):pl15
Spectral analysis of calcium oscillations.
Uhlén P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(23):13420-13424
Ouabain, a steroid hormone that signals with slow calcium oscillations
Aizman O; Uhlén P; Lal M; Brismar H; Aperia A
Article: NATURE. 2000;405(6787):694-697
α-Haemolysin of uropathogenic E-coli induces Ca²⁺ oscillations in renal epithelial cells
Uhlén P; Laestadius Å; Jahnukainen T; Söderblom T; Bäckhed F; Celsi G; Brismar H; Normark S; Aperia A; Richter-Dahlfors A
Article: NATURE NEUROSCIENCE. 2000;3(3):226-230
Anatomical and physiological evidence for D₁ and D₂ dopamine receptor colocalization in neostriatal neurons
Aizman O; Brismar H; Uhlén P; Zettergren E; Levey AI; Forssberg H; Greengard P; Aperia A

Utforskar olika cellsignaleringsfenomen och deras inverkan på kritiska biologiska och medicinska processer med avancerad ljusmikroskopi – Per Uhléns grupp

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