Dagliyans grupp

Publikationer

Utvalda publikationer

• Journal article: SCIENCE ADVANCES. 2023;9(46):eadh1110

  Engineering memory with an extrinsically disordered kinase

  Ripoli C; Dagliyan O; Renna P; Pastore F; Paciello F; Sollazzo R; Rinaudo M; Battistoni M; Martini S; Tramutola A; Sattin A; Barone E; Saneyoshi T; Fellin T; Hayashi Y; Grassi C
• Journal article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023;24(2):917

  A Bioengineering Strategy to Control ADAM10 Activity in Living Cells

  Pastore F; Battistoni M; Sollazzo R; Renna P; Paciello F; Li Puma DD; Barone E; Dagliyan O; Ripoli C; Grassi C
• Journal article: BIOENGINEERING & TRANSLATIONAL MEDICINE. 2022;7(2):e10292

  Engineering a switchable single-chain TEV protease to control protein maturation in living neurons

  Renna P; Ripoli C; Dagliyan O; Pastore F; Rinaudo M; Re A; Paciello F; Grassi C
• Journal article: NATURE COMMUNICATIONS. 2022;13(1):430

  Expression of the transcription factor PU.1 induces the generation of microglia-like cells in human cortical organoids

  Cakir B; Tanaka Y; Kiral FR; Xiang Y; Dagliyan O; Wang J; Lee M; Greaney AM; Yang WS; DuBoulay C; Kural MH; Patterson B; Zhong M; Kim J; Bai Y; Min W; Niklason LE; Patra P; Park I-H
• Journal article: CELL. 2021;184(22):5670-5685.e23

  Biosensors based on peptide exposure show single molecule conformations in live cells

  Liu B; Stone OJ; Pablo M; Herron JC; Nogueira AT; Dagliyan O; Grimm JB; Lavis LD; Elston TC; Hahn KM
• Journal article: NATURE. 2021;590(7844):115-121

  Bidirectional perisomatic inhibitory plasticity of a Fos neuronal network.

  Yap E-L; Pettit NL; Davis CP; Nagy MA; Harmin DA; Golden E; Dagliyan O; Lin C; Rudolph S; Sharma N; Griffith EC; Harvey CD; Greenberg ME
• Journal article: NATURE METHODS. 2020;17(9):928-936

  Rational design and implementation of a chemically inducible heterotrimerization system

  Wu HD; Kikuchi M; Dagliyan O; Aragaki AK; Nakamura H; Dokholyan NV; Umehara T; Inoue T
• Journal article: CELL REPORTS. 2020;31(11):107764

  Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers.

  Ozkan-Dagliyan I; Diehl JN; George SD; Schaefer A; Papke B; Klotz-Noack K; Waters AM; Goodwin CM; Gautam P; Pierobon M; Peng S; Gilbert TSK; Lin KH; Dagliyan O; Wennerberg K; Petricoin EF; Tran NL; Bhagwat SV; Tiu RV; Peng S-B; Herring LE; Graves LM; Sers C; Wood KC; Cox AD; Der CJ
• Journal article: CURRENT OPINION IN STRUCTURAL BIOLOGY. 2019;57:17-22

  Controlling protein conformation with light

  Dagliyan O; Hahne KM
• Journal article: NATURE PROTOCOLS. 2019;14(6):1863-1883

  Engineering proteins for allosteric control by light or ligands

  Dagliyan O; Dokholyan NV; Hahn KM
• Journal article: NATURE COMMUNICATIONS. 2018;9(1):4042

  Computational design of chemogenetic and optogenetic split proteins

  Dagliyan O; Krokhotin A; Ozkan-Dagliyan I; Deiters A; Der CJ; Hahn KM; Dokholyan NV
• Journal article: PLOS COMPUTATIONAL BIOLOGY. 2018;14(8):e1006321

  Profiling cellular morphodynamics by spatiotemporal spectrum decomposition

  Ma X; Dagliyan O; Hahn KM; Danuser G
• Journal article: ACS SYNTHETIC BIOLOGY. 2017;6(7):1257-1262

  Engineering Pak1 Allosteric Switches

  Dagliyan O; Karginov AV; Yagishita S; Gale ME; Wang H; DerMardirossian C; Wells CM; Dokholyan NV; Kasai H; Hahn KM
• Journal article: SCIENCE. 2016;354(6318):1441-1444

  Engineering extrinsic disorder to control protein activity in living cells

  Dagliyan O; Tarnawski M; Chu P-H; Shirvanyants D; Schlichting I; Dokholyan NV; Hahn KM
• Journal article: NATURE CHEMICAL BIOLOGY. 2016;12(10):802-809

  FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions

  Hodgson L; Spiering D; Sabouri-Ghomi M; Dagliyan O; DerMardirossian C; Danuser G; Hahn KM
• Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2016;291(8):3682-3692

  Gain-of-Function Mutation W493R in the Epithelial Sodium Channel Allosterically Reconfigures Intersubunit Coupling

  Shobair M; Dagliyan O; Kota P; Dang YL; He H; Stutts MJ; Dokholyan NV
• Journal article: JOURNAL OF MOLECULAR BIOLOGY. 2014;426(10):2082-2097

  Intrinsic Disorder Mediates Cooperative Signal Transduction in STIM1

  Furukawa Y; Teraguchi S; Ikegami T; Dagliyan O; Jin L; Hall D; Dokholyan NV; Namba K; Akira S; Kurosaki T; Baba Y; Standley DM
• Journal article: JOURNAL OF MOLECULAR CELL BIOLOGY. 2014;6(2):104-115

  Computational approaches to understanding protein aggregation in neurodegeneration

  Redler RL; Shirvanyants D; Dagliyan O; Ding F; Kim DN; Kota P; Proctor EA; Ramachandran S; Tandon A; Dokholyan NV
• Journal article: BIOCHEMISTRY. 2013;52(40):7082-7090

  Identification of Novel Integrin Binding Partners for Calcium and Integrin Binding Protein 1 (CIB1): Structural and Thermodynamic Basis of CIB1 Promiscuity

  Freeman TCJ; Black JL; Bray HG; Dagliyan O; Wu YI; Tripathy A; Dokholyan NV; Leisner TM; Parise LV
• Journal article: CHEMISTRY AND BIOLOGY. 2013;20(6):847-856

  Knowledge-Based Design of a Biosensor to Quantify Localized ERK Activation in Living Cells

  Kummer L; Hsu C-W; Dagliyan O; MacNevin C; Kaufholz M; Zimmermann B; Dokholyan NV; Hahn KM; Plueckthun A
• Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(17):6800-6804

  Rational design of a ligand-controlled protein conformational switch

  Dagliyan O; Shirvanyants D; Karginov AV; Ding F; Fee L; Chandrasekaran SN; Freisinger CM; Smolen GA; Huttenlocher A; Hahn KM; Dokholyan NV
• Journal article: PLOS ONE. 2012;7(2):e31787

  Structure Based Discovery of Small Molecules to Regulate the Activity of Human Insulin Degrading Enzyme

  Cakir B; Dagliyan O; Dagyildiz E; Baris I; Kavakli IH; Kizilel S; Turkay M
• Journal article: STRUCTURE. 2011;19(12):1837-1845

  Structural and Dynamic Determinants of Protein-Peptide Recognition

  Dagliyan O; Proctor EA; D'Auria KM; Ding F; Dokholyan NV
• Journal article: PLOS ONE. 2011;6(2):e14579

  Optimization Based Tumor Classification from Microarray Gene Expression Data

  Dagliyan O; Uney-Yuksektepe F; Kavakli IH; Turkay M
• Journal article: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2009;49(10):2403-2411

  Classification of Cytochrome P450 Inhibitors with Respect to Binding Free Energy and pIC₅₀ Using Common Molecular Descriptors

  Dagliyan O; Kavakli IH; Turkay M
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Medarbetare och kontakt

Gruppledare

• 

  Onur Dagliyan

  Biträdande Lektor

  E-postadress onur.dagliyan@ki.se

Alla medarbetare i gruppen

• 

  Onur Dagliyan

  Biträdande Lektor

  E-postadress onur.dagliyan@ki.se
• Lukas Hahn

  Anknuten till Forskning

  E-postadress lukas.hahn@ki.se
• 

  Rajitha Indukuri

  Postdoktor

  E-postadress rajitha.indukuri@ki.se
• 

  Tara Maharjan

  Anknuten till Forskning

  E-postadress tara.maharjan@ki.se
• 

  Batuhan Uygar

  Doktorand

  E-postadress batuhan.uygar@ki.se
• 

  Hang Zeng

  Anknuten till Forskning | Postdoctoral researcher

  E-postadress hang.zeng@ki.se
• Yu Zhang

  Doktorand

  E-postadress yu.zhang.2@ki.se
• 

  Jiao Zhu

  Anknuten till Forskning

  E-postadress jiao.zhu@ki.se
• Zeynep Özahishali

  Extern Student | Forskningsassistent

  E-postadress zeynep.ozahishali@ki.se

Besöksadress

Karolinska Insitutet, MBB, Division of Molecular Neurobiology, Biomedicum 6C, Stokcholm, Sweden