Översättning av mRNA i cancer – Ola Larssons forskargrupp

Publikationer

Utvalda publikationer

• Article: CELL REPORTS. 2022;40(3):111092

  Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR

  Krokowski D; Jobava R; Szkop KJ; Chen C-W; Fu X; Venus S; Guan B-J; Wu J; Gao Z; Banaszuk W; Tchorzewski M; Mu T; Ropelewski P; Merrick WC; Mao Y; Sevval AI; Miranda H; Qian S-B; Manifava M; Ktistakis NT; Vourekas A; Jankowsky E; Topisirovic I; Larsson O; Hatzoglou M
• Article: EMBO JOURNAL. 2019;38(23):e101323

  Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression

  Lorent J; Kusnadi EP; van Hoef V; Rebello RJ; Leibovitch M; Ristau J; Chen S; Lawrence MG; Szkop KJ; Samreen B; Balanathan P; Rapino F; Close P; Bukczynska P; Scharmann K; Takizawa I; Risbridger GP; Selth LA; Leidel SA; Lin Q; Topisirovic I; Larsson O; Furic L
• Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2019;200(3):348-358

  Distinct Cancer-Promoting Stromal Gene Expression Depending on Lung Function

  Sandri BJ; Masvidal L; Murie C; Bartish M; Avdulov S; Higgins L; Markowski T; Peterson M; Bergh J; Yang P; Rolny C; Limper AH; Griffin TJ; Bitterman PB; Wendt CH; Larsson O
• Article: NUCLEIC ACIDS RESEARCH. 2019;47(12):e70

  Generally applicable transcriptome-wide analysis of translation using anota2seq

  Oertlin C; Lorent J; Murie C; Furic L; Topisirovic I; Larsson O
• Article: NUCLEIC ACIDS RESEARCH. 2018;46(1):e3

  Polysome-profiling in small tissue samples

  Liang S; Bellato HM; Lorent J; Lupinacci FCS; Oertlin C; van Hoef V; Andrade VP; Roffe M; Masvidal L; Hajj GNM; Larsson O
• Article: MOLECULAR CELL. 2017;68(5):885-900.e6

  A Unique ISR Program Determines Cellular Responses to Chronic Stress

  Guan B-J; van Hoef V; Jobava R; Elroy-Stein O; Valasek LS; Cargnello M; Gao X-H; Krokowski D; Merrick WC; Kimball SR; Komar AA; Koromilas AE; Wynshaw-Boris A; Topisirovic I; Larsson O; Hatzoglou M
• Article: GENOME RESEARCH. 2016;26(5):636-648

  nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs

  Gandin V; Masvidal L; Hulea L; Gravel S-P; Cargnello M; McLaughlan S; Cai Y; Balanathan P; Morita M; Rajakumar A; Furic L; Pollak M; Porco JAJ; St-Pierre J; Pelletier J; Larsson O; Topisirovic I
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(23):8977-8982

  Distinct perturbation of the translatome by the antidiabetic drug metformin

  Larsson O; Morita M; Topisirovic I; Alain T; Blouin M-J; Pollak M; Sonenberg N
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(50):21487-21492

  Identification of differential translation in genome wide studies

  Larsson O; Sonenberg N; Nadon R
• Article: CANCER RESEARCH. 2007;67(14):6814-6824

  Eukaryotic translation initiation factor 4E-Induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors

  Larsson O; Li S; Issaenko OA; Avdulov S; Peterson M; Smith K; Bitterman PB; Polunovsky VA

Medarbetare och kontakt

Gruppledare

• 

  Ola Larsson

  Senior Forskare | Prefekt | Docent

  Telefon +46852481228

  E-postadress ola.larsson@ki.se

Alla medarbetare i gruppen

• Margarita Bartish

  Anknuten till Forskning

  E-postadress margarita.bartish@ki.se
• Solenne Bleuse

  Postdoktorala Studier

  E-postadress solenne.bleuse@ki.se
• 

  Sherwin Chan

  Biträdande Lektor

  E-postadress sherwin.chan@ki.se
• Arash Darzian Rostami

  Doktorand

  E-postadress arash.darzian.rostami@ki.se
• Adrian Garcia Moreno

  Postdoktorala Studier

  E-postadress adrian.garcia.moreno@ki.se
• Kiana Hosseinpour Moghaddam

  Doktorand

  E-postadress kiana.hosseinpour.moghaddam@ki.se
• 

  Ola Larsson

  Senior Forskare | Prefekt | Docent

  Telefon +46852481228

  E-postadress ola.larsson@ki.se
• Krzysztof Szkop

  Postdoktorala Studier

  E-postadress krzysztof.szkop@ki.se
• Kathleen Watt

  Postdoktorala Studier

  E-postadress kathleen.watt@ki.se
• 

  Alana Panzenhagen

  Postdoktorala Studier

  E-postadress alana.panzenhagen@ki.se