Ola Larssons forskargrupp

Mer information finns på den engelska sidan.

Gruppmedlemmar

Ola Larsson, gruppledare
Sherwin Chan, biträdande lektor
Kathleen Watt, post-doc
Solenne Bleuse, post-doc
Krzyszof Szkop, post-doc
Arash Rostami, doktorand
Inci Aksoylu, doktorand
Kiana Hosseinpour Moghaddam, doktorand

Utvalda publikationer

Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR.
Krokowski D, Jobava R, Szkop KJ, Chen CW, Fu X, Venus S, Guan BJ, Wu J, Gao Z, Banaszuk W, Tchorzewski M, Mu T, Ropelewski P, Merrick WC, Mao Y, Sevval AI, Miranda H, Qian SB, Manifava M, Ktistakis NT, Vourekas A, Jankowsky E, Topisirovic I, Larsson O, Hatzoglou M
Cell Rep 2022 Jul;40(3):111092

Translational offsetting as a mode of estrogen receptor α-dependent regulation of gene expression.
Lorent J, Kusnadi EP, van Hoef V, Rebello RJ, Leibovitch M, Ristau J, Chen S, Lawrence MG, Szkop KJ, Samreen B, Balanathan P, Rapino F, Close P, Bukczynska P, Scharmann K, Takizawa I, Risbridger GP, Selth LA, Leidel SA, Lin Q, Topisirovic I, Larsson O, Furic L
EMBO J 2019 Dec;38(23):e101323

Distinct Cancer-Promoting Stromal Gene Expression Depending on Lung Function.
Sandri BJ, Masvidal L, Murie C, Bartish M, Avdulov S, Higgins L, Markowski T, Peterson M, Bergh J, Yang P, Rolny C, Limper AH, Griffin TJ, Bitterman PB, Wendt CH, Larsson O
Am J Respir Crit Care Med 2019 Aug;200(3):348-358

Generally applicable transcriptome-wide analysis of translation using anota2seq.
Oertlin C, Lorent J, Murie C, Furic L, Topisirovic I, Larsson O
Nucleic Acids Res 2019 Jul;47(12):e70

Polysome-profiling in small tissue samples.
Liang S, Bellato HM, Lorent J, Lupinacci FCS, Oertlin C, van Hoef V, Andrade VP, Roffé M, Masvidal L, Hajj GNM, Larsson O
Nucleic Acids Res 2018 Jan;46(1):e3

A Unique ISR Program Determines Cellular Responses to Chronic Stress.
Guan BJ, van Hoef V, Jobava R, Elroy-Stein O, Valasek LS, Cargnello M, Gao XH, Krokowski D, Merrick WC, Kimball SR, Komar AA, Koromilas AE, Wynshaw-Boris A, Topisirovic I, Larsson O, Hatzoglou M
Mol Cell 2017 Dec;68(5):885-900.e6

nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs.
Gandin V, Masvidal L, Hulea L, Gravel SP, Cargnello M, McLaughlan S, Cai Y, Balanathan P, Morita M, Rajakumar A, Furic L, Pollak M, Porco JA, St-Pierre J, Pelletier J, Larsson O, Topisirovic I
Genome Res 2016 May;26(5):636-48

Distinct perturbation of the translatome by the antidiabetic drug metformin.
Larsson O, Morita M, Topisirovic I, Alain T, Blouin MJ, Pollak M, et al
Proc. Natl. Acad. Sci. U.S.A. 2012 Jun;109(23):8977-82

Identification of differential translation in genome wide studies.
Larsson O, Sonenberg N, Nadon R
Proc. Natl. Acad. Sci. U.S.A. 2010 Dec;107(50):21487-92

Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors.
Larsson O, Li S, Issaenko OA, Avdulov S, Peterson M, Smith K, Bitterman PB, Polunovsky VA
Cancer Res 2007 Jul;67(14):6814-24