Molekylär och nätverks-neurofarmakologi – Gilberto Fisones grupp

Vi studerar molekylära och cellulära avvikelser samt avvikelser i kretsar som är involverade i neurodegenerativa och neuropsykiatriska sjukdomar. Vi är särskilt intresserade av de motoriska och icke-motoriska symtomen vid Parkinsons sjukdom och av de komplikationer som är förknippade med administrering av antiparkinsonläkemedel.

Publikationer

Utvalda publikationer

Article: BIOMEDICINES. 2021;9(6):598

A Guide to the Generation of a 6-Hydroxydopamine Mouse Model of Parkinson's Disease for the Study of Non-Motor Symptoms.

Masini D; Plewnia C; Bertho M; Scalbert N; Caggiano V; Fisone G
Article: MOVEMENT DISORDERS. 2021;36(5):1137-1146

Involvement of Autophagy in Levodopa-Induced Dyskinesia.

Feyder M; Plewnia C; Lieberman OJ; Spigolon G; Piccin A; Urbina L; Dehay B; Li Q; Nilsson P; Altun M; Santini E; Sulzer D; Bezard E; Borgkvist A; Fisone G
Review: FRONTIERS IN PHARMACOLOGY. 2019;10:1414

Sleep Disorders in Rodent Models of Parkinson's Disease.

Medeiros DDC; Lopes Aguiar C; Moraes MFD; Fisone G
Article: NEUROBIOLOGY OF DISEASE. 2018;110:37-46

cJun N-terminal kinase (JNK) mediates cortico-striatal signaling in a model of Parkinson's disease.

Spigolon G; Cavaccini A; Trusel M; Tonini R; Fisone G
Article: NATURE. 2018;553(7689):455-460

Midbrain circuits that set locomotor speed and gait selection.

Caggiano V; Leiras R; Goñi-Erro H; Masini D; Bellardita C; Bouvier J; Caldeira V; Fisone G; Kiehn O
Article: NATURE BIOTECHNOLOGY. 2017;35(5):444-452

Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model.

Rivetti di Val Cervo P; Romanov RA; Spigolon G; Masini D; Martín-Montañez E; Toledo EM; La Manno G; Feyder M; Pifl C; Ng Y-H; Sánchez SP; Linnarsson S; Wernig M; Harkany T; Fisone G; Arenas E
Article: TRANSLATIONAL PSYCHIATRY. 2017;7(4):e1088

The histamine H3 receptor antagonist thioperamide rescues circadian rhythm and memory function in experimental parkinsonism.

Masini D; Lopes-Aguiar C; Bonito-Oliva A; Papadia D; Andersson R; Fisahn A; Fisone G
Article: BIOLOGICAL PSYCHIATRY. 2016;79(5):362-371

A Role for Mitogen- and Stress-Activated Kinase 1 in L-DOPA-Induced Dyskinesia and ∆FosB Expression.

Feyder M; Södersten E; Santini E; Vialou V; LaPlant Q; Watts EL; Spigolon G; Hansen K; Caboche J; Nestler EJ; Fisone G

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