Lennart Nilsson
Professor Emeritus/Emerita | Docent
E-postadress: lennart.nilsson@ki.se
Telefon: +46852481099
Besöksadress: Blickagången 16, 14151 Flemingsberg
Postadress: H7 Medicin, Huddinge, H7 Bionut Avdelningsgemensamt, 171 77 Stockholm
Om mig
- Jag är i min forskning intresserad av grundläggande mekanismer för cellens väsentliga funktioner och hur de påverkas av olika yttre omständigheter såsom mutationer och olika substanser, t.ex. läkemedel. Förutom med min egen forskning arbetar jag med forskarutbildningsfrågor, som jag de senaste 10 åren har erfarenhet av ur flera perspektiv: som studierektor för forskarutbildning vid min institution och som ledamot av disputationskommittén, samt senast som ledamot i Styrelsen för forskarutbildning (2012-2016). Jag har även som huvudhandledare handlett 13 doktorander till disputation
Forskning är centralt för forskarutbildningen, och det är viktigt att doktoranderna får avancerad metod- och ämneskunskap, med både bredd och djup. Inte bara processen, utan framförallt människorna i den är viktiga. Vi måste kunna attrahera de mest lämpliga studenterna med fallenhet och genuint intresse för forskning och sedan ge dem bästa möjliga förutsättningar
Angelägna frågor
KI i stort
- Rekryteringsprocesser och karriärsystem som främjar kvalitet, transparens och förutsägbarhet
Forskarutbildning
- Framtidens avhandlingar – med färre och mer omfattande arbeten behöver avhandlingens format ses över
- Goda forskningsmiljöer för alla doktorander – program, forskarskolor är viktiga instrument
Förtroendeuppdrag
- Deputy head of department, Dept. of Biosciences and Nutrition (2013-)
- Executive Editor BBA General Subjects (2016- )
- Pro-dean of Doctoral Education, KI (2016-2018)
- Member of the Board of Doctoral Education, KI (2012-2016)
- Member of the management group of the Dept. of Biosciences and Nutrition, KI (2009-)
- Chairman of the National committee for molecular biosciences of KVA (2003-2013), Secretary (2014-2017) Vice-President (2008-2010) and President (2010-2012) of the Int. Soc. for Quantum Biology and Pharmacology Secretary (1996-2000), member (2000-2003) of Europ. Biophys. Soc. Assoc. Exec. Comm. Secretary (1980-1992), Chairman (1992-1995), Board member (2004-2011) of the Swed. Bioph. Soc.
Utbildning
- Civ.ing, KTH-F, 1976
- TeknD, teoretisk fysik, KTH, 1983
- Postdoc, Harvard University, 1983-1984
- Docent, biofysik, KI, 1987
- Professor, KI, 1998
Akademiska priser och utmärkelser
- Lindbomska belöningen, KVA, 1998
Forskningsbeskrivning
- Min forskning har som huvudtema igenkänning och informationsöverföring i protein-nukleinsyrekomplex, och vi använder oss av datorbaserad modellering och simulering av komplexen i atomär detalj. Exempel på system vi studerar är transkriptionsfaktorer och tRNA:mRNA på ribosomen.
Artiklar
- Article: NATURE COMMUNICATIONS. 2024;15(1):1865
- Article: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 2024;1868(2):130534
- Article: JOURNAL OF CHEMICAL THEORY AND COMPUTATION. 2023;19(11):3346-3358
- Article: STRUCTURE. 2022;30(5):733-742.e7
- Article: ANALYTICAL CHEMISTRY. 2019;91(17):11129-11137
- Article: ACS CHEMICAL NEUROSCIENCE. 2019;10(3):1462-1477
- Article: ACS OMEGA. 2019;4(2):3029-3044
- Article: METHODS IN MOLECULAR BIOLOGY. 2019;2036:113-126
- Article: PLOS ONE. 2019;14(2):e0211651
- Article: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 2018;1862(6):1452-1461
- Article: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2018;58(4):773-783
- Article: ELIFE. 2018;7:e32963
- Article: JOURNAL OF PHYSICAL CHEMISTRY B. 2018;122(3):1152-1160
- Article: SCIENTIFIC REPORTS. 2017;7(1):11043
- Article: JOURNAL OF COMPUTATIONAL CHEMISTRY. 2017;38(15):1147-1157
- Article: ACS OMEGA. 2017;2(5):2165-2177
- Article: BIOPHYSICAL CHEMISTRY. 2016;218:7-13
- Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2016;24(20):4826-4834
- Article: SCIENTIFIC REPORTS. 2016;6:30369
- Article: JOURNAL OF COMPUTATIONAL CHEMISTRY. 2016;37(10):896-912
- Article: NATURE COMMUNICATIONS. 2015;6:10050
- Article: JOURNAL OF PHYSICAL CHEMISTRY B. 2015;119(3):1114-1128
- Article: NUCLEIC ACIDS RESEARCH. 2014;42(18):11329-11338
- Article: BIOPOLYMERS. 2014;101(10):985-991
- Article: ORGANIC & BIOMOLECULAR CHEMISTRY. 2014;12(34):6684-6693
- Article: JOURNAL OF CHEMICAL THEORY AND COMPUTATION. 2014;10(8):3532-3540
- Article: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2014;54(4):1129-1142
- Article: BIOCHEMISTRY. 2013;52(34):5730-5745
- Article: RNA. 2013;19(7):916-926
- Article: JOURNAL OF CHEMICAL THEORY AND COMPUTATION. 2013;9(1):834-846
- Article: MOLECULAR MICROBIOLOGY. 2012;86(4):787-804
- Article: BIOCHEMISTRY. 2012;51(41):8189-8207
- Article: JOURNAL OF CHEMICAL THEORY AND COMPUTATION. 2012;8(4):1493-1502
- Article: JOURNAL OF CHEMICAL THEORY AND COMPUTATION. 2012;8(1):348-362
- Article: PLOS ONE. 2012;7(1):e30510
- Article: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 2012;80(1):294-306
- Article: RNA. 2011;17(12):2177-2188
- Article: PHYSICAL BIOLOGY. 2011;8(5):056001
- Article: JOURNAL OF COMPUTATIONAL CHEMISTRY. 2011;32(9):1929-1943
- Article: PLOS ONE. 2011;6(4):e18767
- Article: PLOS ONE. 2011;6(3):e17587
- Article: PLOS ONE. 2011;6(5):e20116
- Article: PLOS ONE. 2010;5(12):e15594
- Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(34):25875-25879
- Article: JOURNAL OF CHEMICAL THEORY AND COMPUTATION. 2010;6(6):1871-1883
- Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2010;18(10):3518-3534
- Article: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 2009;77(4):842-856
- Article: PLOS COMPUTATIONAL BIOLOGY. 2009;5(8):e1000461
- Article: JOURNAL OF COMPUTATIONAL CHEMISTRY. 2009;30(9):1490-1498
- Article: JOURNAL OF PHYSICAL CHEMISTRY B. 2009;113(24):8210-8213
- Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2009;1792(2):132-139
- Article: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 2008;73(2):325-337
- Article: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 2008;26(2):163-173
- Article: NUCLEIC ACIDS RESEARCH. 2008;36(12):4211-4219
- Article: BIOCHEMISTRY. 2008;47(18):5205-5215
- Article: JOURNAL OF MOLECULAR BIOLOGY. 2008;377(3):691-705
- Article: NUCLEIC ACIDS RESEARCH. 2008;36(5):1508-1516
- Article: JOURNAL OF MOLECULAR BIOLOGY. 2007;372(3):798-816
- Article: JOURNAL OF PHYSICAL CHEMISTRY B. 2007;111(32):9621-9627
- Article: BIOCHEMISTRY. 2007;46(29):8537-8549
- Article: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 2007;24(6):525-536
- Article: BIOCHEMISTRY. 2007;46(11):3366-3377
- Article: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2007;36(3):213-224
- Article: BIOPHYSICAL JOURNAL. 2006;91(9):3151-3161
- Article: JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS. 2006;24(1):1-15
- Article: BIOCHEMISTRY. 2006;45(24):7483-7492
- Article: NUCLEIC ACIDS RESEARCH. 2006;34(1):275-285
- Article: COMPUTATIONAL AND THEORETICAL CHEMISTRY. 2006;758(2-3):139-148
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2005;102(39):13867-13872
- Article: JOURNAL OF CHEMICAL THEORY AND COMPUTATION. 2005;1(5):986-993
- Article: MOLECULAR ENDOCRINOLOGY. 2005;19(8):1960-1977
- Article: BIOPHYSICAL JOURNAL. 2005;89(2):842-857
- Article: JOURNAL OF PHYSICAL CHEMISTRY B. 2005;109(18):9119-9131
- Article: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 2005;59(2):170-182
- Article: RNA. 2005;11(5):609-618
- Article: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2004;33(7):651-655
- Article: BIOCHEMICAL JOURNAL. 2004;381(Pt 2):489-494
- Article: HUMAN MUTATION. 2004;23(6):599-611
- Article: STRUCTURE. 2004;12(2):289-300
- Article: BIOPHYSICAL JOURNAL. 2003;85(6):3646-3658
- Article: BIOPHYSICAL JOURNAL. 2003;85(6):3445-3459
- Article: JOURNAL OF COMPUTATIONAL CHEMISTRY. 2003;24(12):1383-1389
- Article: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 2002;49(1):24-36
- Article: JOURNAL OF COMPUTATIONAL CHEMISTRY. 2002;23(13):1211-1219
- Article: CHEMICAL PHYSICS LETTERS. 2002;363(1-2):39-44
- Article: JOURNAL OF PHYSICAL CHEMISTRY B. 2002;106(36):9440-9445
- Article: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2002;31(4):306-316
- Article: BIOPHYSICAL JOURNAL. 2002;82(3):1554-1569
- Article: JOURNAL OF PHYSICAL CHEMISTRY A. 2001;105(43):9954-9960
- Article: CLINICAL ENDOCRINOLOGY. 2001;55(3):363-371
- Article: JOURNAL OF PHYSICAL CHEMISTRY B. 2001;105(33):8028-8035
- Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2001;123(30):7414-7422
- Article: JOURNAL OF MOLECULAR BIOLOGY. 2001;310(2):449-470
- Article: JOURNAL OF CHEMICAL PHYSICS. 2001;114(14):5993-5999
- Article: INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY. 2001;83(3-4):230-244
- Article: BIOPOLYMERS. 2001;61(1):61-76
- Article: BIOPHYSICAL JOURNAL. 2000;79(5):2276-2289
- Article: BIOPHYSICAL JOURNAL. 2000;79(3):1537-1553
- Article: BIOPHYSICAL JOURNAL. 2000;79(3):1213-1227
- Article: JOURNAL OF MEDICINAL CHEMISTRY. 2000;43(9):1780-1792
- Article: CHEMICAL PHYSICS LETTERS. 1999;311(6):459-466
- Article: BIOPHYSICAL JOURNAL. 1999;77(4):1801-1810
- Article: BIOPHYSICAL JOURNAL. 1999;77(4):1782-1800
- Article: BIOPHYSICAL JOURNAL. 1999;77(3):1284-1305
- Article: JOURNAL OF COMPUTATIONAL CHEMISTRY. 1999;20(8):877-885
- Article: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 1999;35(1):101-113
- Article: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 1999;28(2):102-111
- Article: PROTEIN ENGINEERING DESIGN & SELECTION. 1998;11(7):589-600
- Article: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 1998;31(4):417-433
- Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 1998;120(4):619-631
- Article: BIOPHYSICAL JOURNAL. 1998;74(1):394-402
- Article: MOLECULAR IMMUNOLOGY. 1997;34(16-17):1215-1226
- Article: BIOPOLYMERS. 1996;39(6):765-768
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996;93(19):10173-10176
- Article: JOURNAL OF BIOMOLECULAR NMR. 1996;7(4):305-314
- Article: STRUCTURE. 1996;4(5):519-529
- Article: JOURNAL OF CHEMICAL PHYSICS. 1996;104(15):6052-6057
- Article: JOURNAL OF PHYSICAL CHEMISTRY. 1996;100(7):2480-2488
- Article: JOURNAL OF PHYSICAL CHEMISTRY. 1996;100(7):2550-2554
- Article: BIOPHYSICAL JOURNAL. 1995;69(6):2277-2285
- Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 1995;117(44):10832-10840
- Article: JOURNAL OF MOLECULAR BIOLOGY. 1995;253(3):453-472
- Article: JOURNAL OF PHYSICAL CHEMISTRY. 1995;99(40):14876-14884
- Article: JOURNAL OF PHYSICAL CHEMISTRY. 1995;99(35):13056-13058
- Article: BIOPHYSICAL JOURNAL. 1995;69(2):329-339
- Article: BIOCHEMISTRY. 1995;34(5):1475-1481
- Article: BIOPHYSICAL JOURNAL. 1995;68(2):402-426
- Article: PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS. 1995;21(1):57-67
- Article: HUMAN MOLECULAR GENETICS. 1995;4(1):51-58
- Visa fler
Alla övriga publikationer
- Review: FEBS JOURNAL. 2015;282(20):3899-3917
- Other: BIOPHYSICAL JOURNAL. 2015;108(12):2755-2756
- Editorial comment: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1850(5):859-860
- Other: BIOPHYSICAL JOURNAL. 2013;104(9):1840-1841
- Review: JOURNAL OF COMPUTATIONAL CHEMISTRY. 2009;30(10):1545-1614
- Review: CURRENT OPINION IN STRUCTURAL BIOLOGY. 2008;18(2):194-199
- Published conference paper: THEORETICAL CHEMISTRY ACCOUNTS. 2007;117(2):267-273
- Editorial comment: CHEMICAL PHYSICS LETTERS. 2004;393(1-3):282-283
- Review: QUARTERLY REVIEWS OF BIOPHYSICS. 2003;36(3):257-306
- Review: ACCOUNTS OF CHEMICAL RESEARCH. 2002;35(6):465-472
- Corrigendum: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 1999;28(4):356
- Published conference paper: COMPUTATIONAL AND THEORETICAL CHEMISTRY. 1997;419:51-55
Anställningar
- Professor Emeritus/Emerita, Medicin, Huddinge, Karolinska Institutet, 2024-2024
Examina och utbildning
- Docent, Biofysik, Karolinska Institutet, 1987