Johan Hartmans forskargrupp

Publikationer

Utvalda publikationer

• Article: EUROPEAN JOURNAL OF CANCER. 2023;191:112953

  Transcriptional intra-tumour heterogeneity predicted by deep learning in routine breast histopathology slides provides independent prognostic information.

  Wang Y; Ali MA; Vallon-Christersson J; Humphreys K; Hartman J; Rantalainen M
• Article: NATURE BIOTECHNOLOGY. 2023;41(8):1085-1088

  Solid-phase capture and profiling of open chromatin by spatial ATAC.

  Llorens-Bobadilla E; Zamboni M; Marklund M; Bhalla N; Chen X; Hartman J; Frisén J; Ståhl PL
• Article: NATURE COMMUNICATIONS. 2023;14(1):982

  Reconstructing clonal tree for phylo-phenotypic characterization of cancer using single-cell transcriptomics.

  Jun S-H; Toosi H; Mold J; Engblom C; Chen X; O'Flanagan C; Hagemann-Jensen M; Sandberg R; Aparicio S; Hartman J; Roth A; Lagergren J
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(1):e2209856120

  Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction.

  Chen X; Sifakis EG; Robertson S; Neo SY; Jun S-H; Tong L; Hui Min AT; Lövrot J; Hellgren R; Margolin S; Bergh J; Foukakis T; Lagergren J; Lundqvist A; Ma R; Hartman J
• Article: CANCERS. 2022;14(11):2615

  Real World Evaluation of the Prosigna/PAM50 Test in a Node-Negative Postmenopausal Swedish Population: A Multicenter Study.

  Kjällquist U; Acs B; Margolin S; Karlsson E; Kessler LE; Garcia Hernandez S; Ekholm M; Lundgren C; Olsson E; Lindman H; Foukakis T; Matikas A; Hartman J
• Article: ANNALS OF ONCOLOGY. 2022;33(1):89-98

  Improved breast cancer histological grading using deep learning.

  Wang Y; Acs B; Robertson S; Liu B; Solorzano L; Wählby C; Hartman J; Rantalainen M
• Article: CANCER RESEARCH. 2021;81(19):5115-5126

  Predicting Molecular Phenotypes from Histopathology Images: A Transcriptome-Wide Expression-Morphology Analysis in Breast Cancer.

  Wang Y; Kartasalo K; Weitz P; Ács B; Valkonen M; Larsson C; Ruusuvuori P; Hartman J; Rantalainen M
• Article: CANCERS. 2021;13(5):1166

  Variability in Breast Cancer Biomarker Assessment and the Effect on Oncological Treatment Decisions: A Nationwide 5-Year Population-Based Study.

  Acs B; Fredriksson I; Rönnlund C; Hagerling C; Ehinger A; Kovács A; Røge R; Bergh J; Hartman J
• Article: JOURNAL OF CLINICAL INVESTIGATION. 2020;130(3):1185-1198

  CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment.

  Neo SY; Yang Y; Record J; Ma R; Chen X; Chen Z; Tobin NP; Blake E; Seitz C; Thomas R; Wagner AK; Andersson J; de Boniface J; Bergh J; Murray S; Alici E; Childs R; Johansson M; Westerberg LS; Haglund F; Hartman J; Lundqvist A
• Preprint: RESEARCH SQUARE. 2019

  CUTseq is a versatile method for preparing multiplexed DNA sequencing libraries from low-input samples

  Zhang X; Garnerone S; Simonetti M; Harbers L; Nicoś M; Mirzazadeh R; Venesio T; Sapino A; Hartman J; Marchiò C; Bienko M; Crosetto N
• Article: CELL. 2018;173(4):879-893.e13

  Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing.

  Kim C; Gao R; Sei E; Brandt R; Hartman J; Hatschek T; Crosetto N; Foukakis T; Navin NE
• Article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(4):1355-1370

  Evolutionary history of metastatic breast cancer reveals minimal seeding from axillary lymph nodes.

  Ullah I; Karthik G-M; Alkodsi A; Kjällquist U; Stålhammar G; Lövrot J; Martinez N-F; Lagergren J; Hautaniemi S; Hartman J; Bergh J
• Review: TRANSLATIONAL RESEARCH. 2018;194:19-35

  Digital image analysis in breast pathology-from image processing techniques to artificial intelligence.

  Robertson S; Azizpour H; Smith K; Hartman J
• Article: JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. 2017;109(3):1-14

  Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.

  Ma R; Karthik G-M; Lövrot J; Haglund F; Rosin G; Katchy A; Zhang X; Viberg L; Frisell J; Williams C; Linder S; Fredriksson I; Hartman J
• Article: SCIENTIFIC REPORTS. 2016;6:38037

  Sequencing-based breast cancer diagnostics as an alternative to routine biomarkers.

  Rantalainen M; Klevebring D; Lindberg J; Ivansson E; Rosin G; Kis L; Celebioglu F; Fredriksson I; Czene K; Frisell J; Hartman J; Bergh J; Grönberg H
• Article: MODERN PATHOLOGY. 2016;29(4):318-329

  Digital image analysis outperforms manual biomarker assessment in breast cancer.

  Stålhammar G; Fuentes Martinez N; Lippert M; Tobin NP; Mølholm I; Kis L; Rosin G; Rantalainen M; Pedersen L; Bergh J; Grunkin M; Hartman J
• Article: CANCER LETTERS. 2015;367(1):76-87

  mTOR inhibitors counteract tamoxifen-induced activation of breast cancer stem cells.

  Karthik G-M; Ma R; Lövrot J; Kis LL; Lindh C; Blomquist L; Fredriksson I; Bergh J; Hartman J

Medarbetare och kontakt

Gruppledare

• 

  Johan Hartman

  Professor/Överläkare | Docent

  Telefon +46852481217

  E-postadress johan.hartman@ki.se

Alla medlemmar i gruppen

• Balazs Acs

  Anknuten till Forskning

  E-postadress balazs.acs@ki.se
• 

  Ceren Boyaci

  Doktorand

  E-postadress ceren.boyaci@ki.se
• 

  Xinsong Chen

  Forskningsspecialist | Postdoktor | Doktorand

  E-postadress xinsong.chen@ki.se
• Eugenia Colon

  Anknuten till Forskning

  E-postadress eugenia.colon.2@ki.se
• 

  Johan Hartman

  Professor/Överläkare | Docent

  Telefon +46852481217

  E-postadress johan.hartman@ki.se
• Emelie Karlsson

  Forskningssamordnare

  Telefon +46852481215

  E-postadress emelie.karlsson.2@ki.se
• Tianyi Li

  Postdoktor

  Telefon +46852482881

  E-postadress tianyi.li.2@ki.se
• 

  Stephanie Robertson

  Anknuten till Forskning

  E-postadress stephanie.robertson@ki.se
• Caroline Rönnlund

  Doktorand

  E-postadress caroline.ronnlund@ki.se
• Sanna Steen

  Anknuten till Forskning

  E-postadress sanna.steen.2@ki.se
• 

  Wenwen Sun

  Postdoktorala Studier

  E-postadress wenwen.sun@ki.se
• Qiao Yang

  Doktorand

  E-postadress qiao.yang@ki.se