Wanda Christ

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: PLOS PATHOGENS. 2025;21(4):e1013042
IL-6 trans-signaling mediates cytokine secretion and barrier dysfunction in hantavirus-infected cells and correlate to severity in HFRS
Maleki KT; Niemetz L; Christ W; Bystroem JW; Thunberg T; Ahlm C; Klingstroem J
Article: ACS CHEMICAL NEUROSCIENCE. 2024;15(22):4095-4104
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
Christ W; Kapell S; Sobkowiak MJ; Mermelekas G; Evertsson B; Sork H; Saher O; Bazaz S; Gustafsson O; Cardenas EI; Villa V; Ricciarelli R; Sandberg JK; Bergquist J; Sturchio A; Svenningsson P; Malm T; Espay AJ; Pernemalm M; Lindeen A; Klingstrom J; El Andaloussi S; Ezzat K
Article: HEALTH SECURITY. 2024;22(5):394-397
Logistics for Rapid Isolation of Viruses From Humans
Bacchus P; Christ W; Frisell A; Greilert-Norin N; Marking U; Havervall S; Leopoldson F; Markstrom A-C; Potapeiko A; Gisselsson D; Thalin C; Klingstrom J; Brave A; Blom K; Groenheit R
Article: MOLECULAR THERAPY. 2024;32(9):3012-3024
Discovery of a novel inhibitor of macropinocytosis with antiviral activity
Porebski B; Christ W; Corman A; Haraldsson M; Barz M; Lidemalm L; Haggblad M; Ilmain J; Wright SC; Murga M; Schlegel J; Jarvius M; Lapins M; Sezgin E; Bhabha G; Lauschke VM; Carreras-Puigvert J; Lafarga M; Klingstrom J; Huhn D; Fernandez-Capetillo O
Article: JOURNAL OF INFECTIOUS DISEASES. 2024;230(2):e318-e326
Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19
Strunz B; Maucourant C; Mehta A; Wan H; Du L; Sun D; Chen P; Nordlander A; Gao Y; Cornillet M; Bister J; Kvedaraite E; Christ W; Klingstrom J; Geanon D; Parke A; Ekwall-Larson A; Rivino L; MacAry PA; Aleman S; Buggert M; Ljunggren H-G; Pan-Hammarstrom Q; Lund-Johansen F; Stralin K; Bjorkstrom NK
Article: PLOS PATHOGENS. 2024;20(7):e1012390
Innate lymphoid cells are activated in HFRS, and their function can be modulated by hantavirus-induced type I interferons
Garcia M; Garcia AC; Weigel W; Christ W; Lira-Junior R; Wirth L; Tauriainen J; Maleki K; Vanoni G; Vaheri A; Makela S; Mustonen J; Nordgren J; Smed-Sorensen A; Strandin T; Mjosberg J; Klingstrom J
Article: VIRUS RESEARCH. 2024;339:199271
SARS-CoV-2 variant-specific differences in inhibiting the effects of the PKR-activated integrated stress response
Christ W; Klingstrom J; Tynell J
Article: NATURE COMMUNICATIONS. 2023;14(1):5921
Comprehensive proteomics and meta-analysis of COVID-19 host response
Babacic H; Christ W; Araujo JE; Mermelekas G; Sharma N; Tynell J; Garcia M; Varnaite R; Asgeirsson H; Glans H; Lehtioe J; Gredmark-Russ S; Klingstroem J; Pernemalm M
Article: CELL REPORTS. 2023;42(8):112835
Super-resolution proximity labeling reveals anti-viral protein network and its structural changes against SARS-CoV-2 viral proteins
Lee Y-B; Jung M; Kim J; Charles A; Christ W; Kang J; Kang M-G; Kwak C; Klingstrom J; Smed-Sorensen A; Kim J-S; Mun JY; Rhee H-W
Article: NATURE COMMUNICATIONS. 2023;14(1):2164
Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19
Yu M; Charles A; Cagigi A; Christ W; osterberg B; Falck-Jones S; Azizmohammadi L; ahlberg E; Falck-Jones R; Svensson J; Nie M; Warnqvist A; Hellgren F; Lenart K; Arcoverde Cerveira R; Ols S; Lindgren G; Lin A; Maecker H; Bell M; Johansson N; Albert J; Sundling C; Czarnewski P; Klingstroem J; Faernert A; Lore K; Smed-Soerensen A
Article: NATURE COMMUNICATIONS. 2023;14(1):1577
Correlates of protection and viral load trajectories in omicron breakthrough infections in triple vaccinated healthcare workers
Marking U; Havervall S; Norin NG; Bladh O; Christ W; Gordon M; Ng H; Blom K; Phillipson M; Mangsbo S; Alm JJ; Smed-Sorensen A; Nilsson P; Hober S; Aberg M; Klingstroem J; Thalin C
Article: EMBO MOLECULAR MEDICINE. 2022;14(8):e15230
Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants
Monteil V; Eaton B; Postnikova E; Murphy M; Braunsfeld B; Crozier I; Kricek F; Niederhofer J; Schwarzbock A; Breid H; Devignot S; Klingstrom J; Thalin C; Kellner MJ; Christ W; Havervall S; Mereiter S; Knapp S; Jimenez AS; Bugajska-Schretter A; Dohnal A; Ruf C; Gugenberger R; Hagelkruys A; Montserrat N; Kozieradzki I; Ali OH; Stadlmann J; Holbrook MR; Schmaljohn C; Oostenbrink C; Shoemaker RH; Mirazimi A; Wirnsberger G; Penninger JM
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2022;42(6):1130-1136
Neutralizing SARS-CoV-2 Antibodies in Commercial Immunoglobulin Products Give Patients with X-Linked Agammaglobulinemia Limited Passive Immunity to the Omicron Variant
Lindahl H; Klingstrom J; Da Silva Rodrigues R; Christ W; Chen P; Ljunggren H-G; Buggert M; Aleman S; Smith CIE; Bergman P
Article: IMMUNITY INFLAMMATION AND DISEASE. 2022;10(4):e595
Long-term SARS-CoV-2-specific and cross-reactive cellular immune responses correlate with humoral responses, disease severity, and symptomatology
Lauren I; Havervall S; Ng H; Lord M; Pettke A; Greilert-Norin N; Gabrielsson L; Chourlia A; Amoedo-Leite C; Josyula VS; Eltahir M; Kerzeli I; Falk AJ; Hober J; Christ W; Wiberg A; Hedhammar M; Tegel H; Burman J; Xu F; Pin E; Manberg A; Klingstrom J; Christoffersson G; Hober S; Nilsson P; Philipson M; Donnes P; Lindsay R; Thalin C; Mangsbo S
Article: CELL REPORTS. 2022;38(10):110503
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Hammer Q; Dunst J; Christ W; Picarazzi F; Wendorff M; Momayyezi P; Huhn O; Netskar HK; Maleki KT; Garcia M; Sekine T; Sohlberg E; Azzimato V; Aouadi M; Degenhardt F; Franke A; Spallotta F; Mori M; Michaelsson J; Bjorkstrom NK; Rueckert T; Romagnani C; Horowitz A; Klingstrom J; Ljunggren H-G; Malmberg K-J
Article: SCIENCE. 2022;375(6584):1041-1047
Broad anti-SARS-CoV-2 antibody immunity induced by heterologous ChAdOx1/mRNA-1273 vaccination
Kaku CI; Champney ER; Normark J; Garcia M; Johnson CE; Ahlm C; Christ W; Sakharkar M; Ackerman ME; Klingstrom J; Forsell MNE; Walker LM
Article: VACCINES. 2022;10(3):359
Duration of SARS-CoV-2 Immune Responses Up to Six Months Following Homologous or Heterologous Primary Immunization with ChAdOx1 nCoV-19 and BNT162b2 mRNA Vaccines
Marking U; Havervall S; Greilert-Norin N; Ng H; Blom K; Nilsson P; Phillipson M; Hober S; Nilsson C; Mangsbo S; Christ W; Klingstrom J; Gordon M; Aberg M; Thalin C
Article: NEW BIOTECHNOLOGY. 2022;66:46-52
A cell-free high throughput assay for assessment of SARS-CoV-2 neutralizing antibodies
Mravinacova S; Jonsson M; Christ W; Klingstrom J; Yousef J; Hellstrom C; Hedhammar M; Havervall S; Thalin C; Pin E; Tegel H; Nilsson P; Manberg A; Hober S
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2022;11(4):e1388
Impact of SARS-CoV-2 infection on vaccine-induced immune responses over time
Havervall S; Marking U; Greilert-Norin N; Gordon M; Ng H; Christ W; Phillipson M; Nilsson P; Hober S; Blom K; Klingstrom J; Mangsbo S; Aberg M; Thalin C
Article: PLOS ONE. 2022;17(1):e0262169
SARS-CoV-2 induces a durable and antigen specific humoral immunity after asymptomatic to mild COVID-19 infection
Havervall S; Falk AJ; Klingstrom J; Ng H; Greilert-Norin N; Gabrielsson L; Salomonsson A-C; Isaksson E; Rudberg A-S; Hellstrom C; Andersson E; Olofsson J; Skoglund L; Yousef J; Pin E; Christ W; Olausson M; Hedhammar M; Tegel H; Mangsbo S; Phillipson M; Manberg A; Hober S; Nilsson P; Thalin C
Article: BMC INFECTIOUS DISEASES. 2021;21(1):494
Shedding of infectious SARS-CoV-2 by hospitalized COVID-19 patients in relation to serum antibody responses
Glans H; Gredmark-Russ S; Olausson M; Falck-Jones S; Varnaite R; Christ W; Maleki KT; Karlberg ML; Broddesson S; Falck-Jones R; Bell M; Johansson N; Farnert A; Smed-Sorensen A; Klingstroem J; Brave A
Article: CELL REPORTS MEDICINE. 2021;2(3):100220
MAIT cell activation is associated with disease severity markers in acute hantavirus infection
Maleki KT; Tauriainen J; Garcia M; Kerkman PF; Christ W; Dias J; Bystrom JW; Leeansyah E; Forsell MN; Ljunggren H-G; Ahlm C; Bjorkstrom NK; Sandberg JK; Klingstrom J
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306
SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation
Sandberg JT; Varnaite R; Christ W; Chen P; Muvva JR; Maleki KT; Garcia M; Dzidic M; Folkesson E; Skagerberg M; Ahlen G; Frelin L; Sallberg M; Eriksson LI; Rooyackers O; Sonnerborg A; Buggert M; Bjorkstrom NK; Aleman S; Stralin K; Klingstrom J; Ljunggren H-G; Blom K; Gredmark-Russ S
Article: JOURNAL OF IMMUNOLOGY. 2020;205(9):2437-2446
Expansion of SARS-CoV-2-Specific Antibody-Secreting Cells and Generation of Neutralizing Antibodies in Hospitalized COVID-19 Patients
Varnaite R; Garcia M; Glans H; Maleki KT; Sandberg JT; Tynell J; Christ W; Lagerqvist N; Asgeirsson H; Ljunggren H-G; Ahlen G; Frelin L; Sallberg M; Blom K; Klingstrom J; Gredmark-Russ S
Article: JOURNAL OF VIROLOGY. 2020;94(3):e01168-e01119
Puumala and Andes Orthohantaviruses Cause Transient Protein Kinase R-Dependent Formation of Stress Granules
Christ W; Tynell J; Klingstrom J
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2020;9(12):e1224
Innate lymphoid cell composition associates with COVID-19 disease severity
Garcia M; Kokkinou E; Carrasco Garcia A; Parrot T; Palma Medina LM; Maleki KT; Christ W; Varnaite R; Filipovic I; Ljunggren H-G; Bjorkstrom NK; Folkesson E; Rooyackers O; Eriksson LI; Sonnerborg A; Aleman S; Stralin K; Gredmark-Russ S; Klingstrom J; Mjosberg J
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Doctoral thesis: 2024
Hantaviruses and SARS-CoV-2 : cell stress and novel antivirals
Christ W
Letter: LANCET INFECTIOUS DISEASES. 2022;22(7):943-945
Immune responses after omicron infection in triple-vaccinated health-care workers with and without previous SARS-CoV-2 infection
Blom K; Marking U; Havervall S; Norin NG; Gordon M; Garcia M; Tecleab T; Christ W; Forsell M; Phillipson M; Nilsson P; Mangsbo S; Hober S; Aberg M; Klingstrom J; Thalin C
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2021;385(11):1049-1051
Heterologous ChAdOx1 nCoV-19 and mRNA-1273 Vaccination
Normark J; Vikstrom L; Gwon Y-D; Persson I-L; Edin A; Bjorsell T; Dernstedt A; Christ W; Tevell S; Evander M; Klingstrom J; Ahlm C; Forsell M

Anställningar

Postdoktor, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2024-2026
Doktorand, Medicin, Huddinge, Karolinska Institutet, 2019-2024

Examina och utbildning

Medicine Doktorsexamen, Karolinska Institutet, 2024

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