Federico Iovino

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: MOLECULAR MEDICINE. 2025;31(1):170
Bacteriophage-derived endolysins restore antibiotic susceptibility in β-lactam- and macrolide-resistant Streptococcus pneumoniae infections
Vander Elst N; Farmen K; Knorr L; Merlijn L; Iovino F
Article: JAMA NETWORK OPEN. 2024;7(12):e2445497
Adult Work Ability Following Diagnosis of Bacterial Meningitis in Childhood
Mohanty S; Johansson Kostenniemi U; Silfverdal SA; Salomonsson S; Iovino F; Bencina G; Tsoumani E; Bruze G
Article: NEUROBIOLOGY OF DISEASE. 2024;195:106484
Spatio-temporal brain invasion pattern of Streptococcus pneumoniae and dynamic changes in the cellular environment in bacteremia-derived meningitis.
Farmen K; Tofiño-Vian M; Wellfelt K; Olsson L; Iovino F
Article: ISCIENCE. 2024;27(4):109583
The single D380 amino acid substitution increases pneumolysin cytotoxicity towards neuronal cells
Serra S; Iannotti V; Ferrante M; Tofiño-Vian M; Baxendale J; Silberberg G; Kohler TP; Hammerschmidt S; Ulijasz AT; Iovino F
Article: JAMA NETWORK OPEN. 2024;7(1):e2352402
Increased Risk of Long-Term Disabilities Following Childhood Bacterial Meningitis in Sweden.
Mohanty S; Johansson Kostenniemi U; Silfverdal SA; Salomonsson S; Iovino F; Sarpong EM; Bencina G; Bruze G
Article: MBIO. 2022;13(5):e0188622-e01822
Dysfunctional Glymphatic System with Disrupted Aquaporin 4 Expression Pattern on Astrocytes Causes Bacterial Product Accumulation in the CSF during Pneumococcal Meningitis
Generoso JS; Thorsdottir S; Collodel A; Dominguini D; Santo RRE; Petronilho F; Barichello T; Iovino F
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022;119(23):e2122386119
Membrane particles evoke a serotype-independent cross-protection against pneumococcal infection that is dependent on the conserved lipoproteins MalX and PrsA
Narciso AR; Iovino F; Thorsdottir S; Mellroth P; Codemo M; Spoerry C; Righetti F; Muschiol S; Normark S; Nannapaneni P; Henriques-Normark B
Article: PLOS PATHOGENS. 2021;17(3):e1009432
Neuronal death in pneumococcal meningitis is triggered by pneumolysin and RrgA interactions with β-actin
Tabusi M; Thorsdottir S; Lysandrou M; Narciso AR; Minoia M; Srambickal CV; Widengren J; Henriques-Normark B; Iovino F
Article: EMBO MOLECULAR MEDICINE. 2020;12(11):e12695
Mannose receptor-derived peptides neutralize pore-forming toxins and reduce inflammation and development of pneumococcal disease
Subramanian K; Iovino F; Tsikourkitoudi V; Merkl P; Ahmed S; Berry SB; Aschtgen M-S; Svensson M; Bergman P; Sotiriou GA; Henriques-Normark B
Article: CHEMICAL COMMUNICATIONS. 2020;56(51):6989-6992
Silica-coated phosphorescent nanoprobes for selective cell targeting and dynamic bioimaging of pathogen-host cell interactions
Iovino F; Merkl P; Spyrogianni A; Henriques-Normark B; Sotiriou GA
Article: BIOSENSORS & BIOELECTRONICS. 2019;132:286-293
Luminescent CeO₂:Eu³⁺ nanocrystals for robust in situ H₂O₂ real-time detection in bacterial cell cultures
Henning DF; Merkl P; Yun C; Iovino F; Xie L; Mouzourakis E; Moularas C; Deligiannakis Y; Henriques-Normark B; Leifer K; Sotiriou GA
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1968:35-39
Immunofluorescent Staining and High-Resolution Microscopy to Study the Pneumococcal Cell.
Iovino F; Henriques-Normark B
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1968:195-202
IVIS Spectrum CT to Image the Progression of Pneumococcal Infections In Vivo.
Sierakowiak A; Henriques-Normark B; Iovino F
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1968:173-181
In Vivo Mouse Models to Study Pneumococcal Host Interaction and Invasive Pneumococcal Disease.
Iovino F; Sender V; Henriques-Normark B
Article: METHODS IN MOLECULAR BIOLOGY. 2019;1968:53-59
High-Resolution and Super-Resolution Immunofluorescent Microscopy Ex Vivo to Study Pneumococcal Interactions with the Host.
Iovino F; Henriques-Normark B
Article: JOURNAL OF INFECTIOUS DISEASES. 2018;218(3):476-484
Receptor Blockade: A Novel Approach to Protect the Brain From Pneumococcal Invasion
Iovino F; Thorsdottir S; Henriques-Normark B
Article: MBIO. 2018;9(2):e00559-e00518
Immunomodulatory Effects of Pneumococcal Extracellular Vesicles on Cellular and Humoral Host Defenses
Codemo M; Muschiol S; Iovino F; Nannapaneni P; Plant L; Wai SN; Henriques-Normark B
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2017;214(6):1619-1630
pIgR and PEC AM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion
Iovino F; Engelen-Lee J-Y; Brouwer M; van de Beek D; van der Ende A; Seron MV; Mellroth P; Muschiol S; Bergstrand J; Widengren J; Henriques-Normark B
Article: JOURNAL OF CLINICAL INVESTIGATION. 2016;126(8):2821-2826
Pneumococcal meningitis is promoted by single cocci expressing pilus adhesin RrgA
Iovino F; Hammarlof DL; Garriss G; Brovall S; Nannapaneni P; Henriques-Normark B
Article: INFECTION AND IMMUNITY. 2014;82(9):3555-3566
Platelet Endothelial Cell Adhesion Molecule-1, a Putative Receptor for the Adhesion of Streptococcus pneumoniae to the Vascular Endothelium of the Blood-Brain Barrier
Iovino F; Molema G; Bijlsma JJE
Article: MBIO. 2014;5(4):e00984-e00914
The Proteasome-Ubiquitin System Is Required for Efficient Killing of Intracellular Streptococcus pneumoniae by Brain Endothelial Cells
Iovino F; Gradstedt H; Bijlsma JJ
Article: PLOS ONE. 2014;9(5):e97914
Streptococcus pneumoniae Interacts with pIgR Expressed by the Brain Microvascular Endothelium but Does Not Co-Localize with PAF Receptor
Iovino F; Molema G; Bijlsma JJE
Article: PLOS ONE. 2013;8(7):e68408
Interactions between Blood-Borne Streptococcus pneumoniae and the Blood-Brain Barrier Preceding Meningitis
Iovino F; Orihuela CJ; Moorlag HE; Molema G; Bijlsma JJE
Article: PLOS ONE. 2013;8(6):e65626
Streptococcus pneumoniae Invades Endothelial Host Cells via Multiple Pathways and Is Killed in a Lysosome Dependent Manner
Gradstedt H; Iovino F; Bijlsma JJE
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Anställningar

Senior Forskare, Neurovetenskap, Karolinska Institutet, 2023-
Postdoctoral researcher, Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, 2013-2015

Examina och utbildning

Docent, Medicinsk mikrobiologi, Karolinska Institutet, 2021
PhD degree, Medical Microbiology, Medical Microbiology, University of Groningen, 2013

Uppdrag

Sektionsansvarig, Principal Investigator representative, Neuroscience, Karolinska Institutet, 2022-
Sektionsansvarig, Safety representative, Neuroscience, Karolinska Institutet, 2022-

Priser och utmärkelser

World Expert Recognition, Expertscape, https://nyheter.ki.se/federico-iovino-utsedd-till-world-expert-av-expertscape, 2021
Prize for research in Clinical Neurology, Bjarne Ahlström Memorial Fund, https://news.ki.se/federico-iovino-awarded-the-bjarne-ahlstrom-minnesfonds-pris-2020-for-research-in-clinical, 2020

Handledning

Simona Serra, 2023
Niels Vander Elst, 2023
Miguel Tofiño-Vian, 2021
Kristine Farmen, 2021

Redaktör för vetenskaplig tidskrift

"In vitro and In vivo models for CNS infections", part of the “Methods in Molecular Biology” series, Chefredaktör, 2022
Frontiers in Cellular and Infection Microbiology, Medlem i redaktionskommittén, 2021
Section Clinical Infectious Diseases, Encyclopedia of Infection and Immunity (Elsevier), Biträdande redaktör, https://www.sciencedirect.com/referencework/9780323903035/encyclopedia-of-infection-and-immunity, 2020
"Streptococcus pneumoniae", part of the “Methods in Molecular Biology” series, Chefredaktör, https://www.springer.com/gp/book/9781493991983, 2018

Sakkunniggranskning för vetenskaplig tidskrift

Nature Communications, Cell Systems, PNAS, eBioMedicine (The Lancet), Scientific Reports (Nature publishing group), BMC Journal of Biomedical Science, PLOS One, Journal of Neuroinflammation, Molecular Neurobiology, Brain Research, Cellular and Molecular Neurobiology, Journal of Neuroimmunology, Neurotoxicology and Teratology, Neuroscience Letters, Journal of Innate Immunity, Journal of Immunology, mBio (American Society of Microbiology), PLOS Pathogens, Infection & Immunity, Molecular Microbiology, Journal of Bacteriology, The International Journal of Medical Microbiology, Microbiology (Microbiology Society), Microbial Pathogenesis, Pathogens and Disease (FEMS), Virulence, Frontiers in Cellular and Infection Microbiology, Frontiers in Immunology, Frontiers in Pediatrics, Frontiers in Bioengineering and Biotechnology, Current Research in Microbial Sciences, Infection and Drug Resistance, Heliyon (Cell Press), Experimental and Molecular Pathology, Annals of Medicine, BMJ (British Medical Journal) Case Reports, Journal of Pediatric Infectious Disease Society., Anonymous peer review, 2018

Expert

Evaluator of research applications in international competition, Grant reviewer / Evaluation panel member, European Society of Clinical Microbiology and Infectious Diseases, 2021

Artiklar

Anställningar

Examina och utbildning

Uppdrag

Priser och utmärkelser

Handledning

Redaktör för vetenskaplig tidskrift

Sakkunniggranskning för vetenskaplig tidskrift

Expert

Nyheter från KI

Kalenderhändelser från KI