Ulrika Marklund
Senior Forskare | Docent
E-postadress: ulrika.marklund@ki.se
Telefon: +46852483519
Besöksadress: Solnavägen 9, 6C, 17177 Stockholm
Postadress: C2 Medicinsk biokemi och biofysik, C2 Molekylär neurobiologi Marklund, 171 77 Stockholm
Om mig
My major research interest has always been centered around the development
and function of neural cell types. During my PhD at the Department of Cell
and Molecular Biology at KI, I studied transcriptional determinants of
specific neuronal identities including the dopaminergic and serotonergic
neurons of the brain. I thereafter transitioned my research focus to the
“Brain in the gut” – the Enteric Nervous System, during a postdoc at
National Institute for Medical Research in Mill Hill, London, UK. Since 2013,
I have led my own research group at the Department of Medical Biochemistry
and Biophysics./
1996-2001 Master in Molecular Biology, Umeå University
1999-2000 ERASMUS exchange year, University of Manchester, UK
2002-2008 PhD candidate, Dept Cell and Molecular Biology, Karolinska
Institutet
2009-2010 Postdoc, National Institute for Medical Research- Mill Hill,
London, UK
Forskningsbeskrivning
My research team focuses on neural cell diversity in the Enteric Nervous
System (ENS). By determining the variety of ENS cell subtypes, the
functions they normally serve and their developmental specification we aim to
improve diagnostic and therapeutic principles for gut disorders. The lab
addresses these basic but critical questions by transcriptome analysis
coupled with viral-based activity/gene manipulations using the mouse model.
Artiklar
- Journal article: NATURE NEUROSCIENCE. 2024;:1-2
- Article: STEM CELL REPORTS. 2021;16(11):2718-2735
- Article: JOURNAL OF CLINICAL INVESTIGATION. 2021;131(6):145837
- Article: NATURE NEUROSCIENCE. 2021;24(1):34-46
- Article: FRONTIERS IN MOLECULAR NEUROSCIENCE. 2019;12:6
- Article: CELL. 2018;174(4):999-1014.e22
- Article: ELIFE. 2018;7:e34465
- Article: GASTROENTEROLOGY. 2018;154(3):624-636
- Article: SCIENCE. 2017;357(6346):eaal3753
- Article: JOURNAL OF NEUROSCIENCE. 2016;36(15):4339-4350
- Article: SCIENCE. 2014;345(6192):82-87
- Article: STEM CELLS AND DEVELOPMENT. 2014;23(1):5-15
- Article: DEVELOPMENT. 2010;137(23):4051-4060
- Article: JOURNAL OF CELL SCIENCE. 2010;123(17):2931-2942
- Article: DEVELOPMENT. 2010;137(3):437-445
- Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(18):7613-7618
- Article: CELL. 2006;124(2):393-405
- Article: NATURE NEUROSCIENCE. 2003;6(9):933-938
Alla övriga publikationer
- Editorial comment: NATURE REVIEWS GASTROENTEROLOGY AND HEPATOLOGY. 2022;19(2):85-86
- Thesis / dissertation: 2008
Forskningsbidrag
- Swedish Research Council1 January 2023 - 31 December 2027
- Swedish Research Council1 January 2021 - 31 December 2024
- Knut and Alice Wallenberg Foundation1 January 2020
- Swedish Research Council1 January 2017 - 31 December 2020
- Swedish Research Council1 January 2013 - 31 December 2016
Anställningar
- Senior Forskare, Medicinsk biokemi och biofysik, Karolinska Institutet, 2022-
Examina och utbildning
- Docent, Neurovetenskap, Karolinska Institutet, 2024
- Filosofie Doktorsexamen, Institutionen för cell- och molekylärbiologi, Karolinska Institutet, 2008