Caroline Ingre's research group

ALS

ALS (amyotrophic lateral sclerosis) is a fatal neuromuscular disease that is characterized by a degeneration of upper and lower motorneurons. The patients experience a weakness usually starting in the upper or lower extremities spreading to other regions weakening both speech and swallowing. Besides the muscle weakness, cognitive dysfunction and behavioral changes are seen in about 50% of the patients and some develop fulminant frontotemporal dementia.