imaging of brain with alzheimer

Our research is focused on the most common forms of dementia including Alzheimer’s disease (AD), dementia with Lewy bodies (DLB), vascular dementia (VaD), frontotemporal lobar degeneration (FTD) and dementia in Parkinson’s disease (PDD).

Research focus

Structural and functional neuroimaging play an important role in understanding the underlying mechanisms of different dementia disorders, potentially contributing to their management and diagnosis. We have a strong focus in different magnetic resonance imaging (MRI) techniques, such as structural MRI, magnetic resonance spectroscopy (MRS), functional MRI, diffusion tensor imaging (DTI), arterial spin labeling (ASL) and susceptibility weighted imaging (SWI). In addition to MRI, we work with other imaging modalities, such as positron emission tomography (PET) and computed tomography (CT).

We work with advanced tools to analysis neuroimaging data such as multivariate methods, machine learning and graph theory. Currently, a large part of the research within the group is focused on unraveling the heterogeneity in AD and to understand the substantial overlap between the different disorders. We believe it is important to work with the latest neuroimaging techniques to obtain a better understanding of the underlying mechanisms of the different diseases, to improve early diagnosis and differential diagnosis.


We have several collaborations within our own department (NVS), with other departments at KI and with other universities in Sweden (Uppsala, Lund, Gothenburg and KTH). We also have strong collaborations with several foreign universities such as the University of Eastern Finland, University of Perugia, University of Stavanger, LaLaguna in Spain, the Mayo Clinic in Rochester and King's College London.

Research support

With special thanks to the following donors for the support they provide or earlier provided to our research:

  • The Swedish Research Council
  • The Swedish Foundation for Strategic Research (SSF)
  • Karolinska Institutet
  • Swedish Alzheimer Association
  • Swedish Brain Foundation
  • ALF
  • StatNeuro, KI
  • HMT
  • Åke Wibergs Stiftelse
  • Stiftelsen Olle Engkvist Byggmästare
  • Birgitta och Sten Westerberg


Selected publications

Staff and contact

Group leader

All members of the group