Residual conditions after polio and neuromuscular diseases – Eva Melin's research group

Our research encompasses both genetic and pathological mechanisms, as well as rehabilitation of residual conditions following polio and other neuromuscular diseases. The research includes, among other things, studies of pain, fatigue, quality of life, and inflammation.

Our research covers both genetic and pathological mechanisms, as well as the rehabilitation of residual conditions following polio and other neuromuscular diseases.

The research includes, amongst other things, studies of pain, fatigue, quality of life and inflammation.

Current projects

Managing fatigue

Managing Fatigue is a digital, structured self-help programme designed to reduce the impact of fatigue on everyday life. The project is being evaluated as part of a research collaboration between Lund University and Karolinska Institutet to investigate whether an internet-based programme can reduce debilitating fatigue and improve activity levels, participation and life satisfaction among people with late effects of polio.

Smärtbarometern (the Pain Barometer)

A clinical and research-oriented tool designed to assess and measure how pain affects activity and participation in everyday life for people living with post-polio syndrome.

Muscle examined using the NeuroFlexor

Muscle changes are being investigated in people with a history of polio, using the NeuroFlexor device. We are also investigating how mechanical properties of muscles (such as elasticity), as measured by the NeuroFlexor, correlate with muscle atrophy, muscle strength, muscle fatigue and pain.

Evaluation of the efficacy of IVIG

A review of previous IVIG treatments to assess responders and non-responders.

Cytokines/neurofilaments

A study of the presence of inflammatory cytokines and neurofilaments, particularly in relation to fatigue and pain in post-polio patients.

Rehab with culture

Rehabilitation involving cultural activities for patients who require a language interpreter and are unable to take part in standard pain rehabilitation groups.

Publications

Selected publications