Anaesthesia and Intensive care – Rebecka Rubenson Wahlin/Anna Schandl's research group

The research group focuses on improving care, treatment and outcomes for patients undergoing surgery and intensive care through clinical, translational and data-driven research. The work includes development and evaluation of treatment strategies, studies of current clinical practice, and identification of short- and long-term complications following critical illness and surgery.

Part of the:

Our research

The group conducts research in perioperative and intensive care. The work is based on clinically relevant research questions and includes the development of new therapies, evaluation of current practices, and investigation of short- and long-term outcomes in critically ill and surgical patients.

The group has several ongoing projects evaluating fluid therapy and coagulopathy in critically ill patients, investigating treatments for perioperative hypotension, examining morbidity in intensive care unit survivors, and developing AI-based decision support for intensive care through the aICU programme.

The clinical research unit is an integral part of the research activities at the Perioperative and Intensive Care Department at Södersjukhuset. The unit consists of two research nurses with extensive experience in clinical research, study monitoring, complex data collection and biobanking.

Collaborations

The research group has established national and international collaborations in the perioperative- and intensive care field, among some: 

Research support 

  • AFA försäkring
  • ALF medicine
  • Cancerfonden
  • Forte
  • LÖF
  • Region Stockholm
  • Innovationsfonden
  • Operations- och intensivvårdsfonden
  • Olof Norlanders Minnesstiftelse
  • Hirsch Fellowship
  • Digital Futures

Publications

All publications from group members

Selected publications

Restriction of Intravenous Fluid in ICU Patients with Septic Shock.
Meyhoff TS, Hjortrup PB, Cronhjort M, Joelsson-Alm E, et al. 
N Engl J Med 2022 Jun;386(26):2459-2470

Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial.
Munch MW, Wahlin RR, Cronhjort M, Hollenberg J, et al.
JAMA 2021 Nov;326(18):1807-1817

Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia.
Granholm A, Kjær MN, Cronhjort M, Wahlin RR, et al.
Intensive Care Med 2022 May;48(5):580-589

Development of an ICU discharge instrument predicting psychological morbidity: a multinational study.
Milton A, Schandl A, Soliman IW, et al.
Intensive Care Med 2018 Dec;44(12):2038-2047

Intensive care nurses' lived experience of altruism and sacrifices during the Covid-19 pandemic: A phenomenological study.
Slettmyr A, Arman M, Andermo S, Schandl A, et al.
J Adv Nurs 2023 Jan;79(1):244-253

Glycemic Control and Risk of Sepsis and Subsequent Mortality in Type 2 Diabetes.
Balintescu A, Lind M, Franko MA, Oldner A, Cronhjort M, et al.
Diabetes Care 2022 Jan;45(1):127-133

Stabilizing life: A grounded theory of surviving critical illness.
Vogel G, Joelsson-Alm E, Forinder U, Svensen C, Sandgren A
Intensive Crit Care Nurs 2021 Dec;67():103096

An observational study of intermediate- or high-dose thromboprophylaxis for critically ill COVID-19 patients.
Jonmarker S, Litorell J, Dahlberg M, Stackelberg O, Everhov ÅH, Söderberg M, Rubenson-Wahlin R, Günther M, Mårtensson J, Hollenberg J, Joelsson-Alm E, Cronhjort M
Acta Anaesthesiol Scand 2022 Mar;66(3):365-374

Family members' experiences of COVID-19 visiting restrictions in the intensive care unit-A qualitative study.
Forsberg T, Isaksson M, Schelin C, Lyngå P, Schandl A
J Clin Nurs 2023 Jan;():

Dosing of thromboprophylaxis and mortality in critically ill COVID-19 patients.
Jonmarker S, Hollenberg J, Dahlberg M, Stackelberg O, Litorell J, Everhov ÅH, Järnbert-Pettersson H, Söderberg M, Grip J, Schandl A, Günther M, Cronhjort M
Crit Care 2020 Nov;24(1):653

Staff and contact

Group leader

All members of the group

Profile image

Eva Kristina Alm

University Nurse | Docent

Research projects

The aICU initiative

Developing next-generation decision support tools for intensive care.
Learn more about the project.

CRITICAL COVID-19 DATABASE

A database including extensive information on patients with critical COVID-19 

NORA 

A cohort of 1004 surgically treated patients undergoing surgery investigating the effects of norepinephrine on hypotension

PREPICS

A cohort of 800 intensive care unit survivors followed during the first year after critical illness with the aim of identifying predictors of HRQL reductions  

ROTEM

Early identification of severe coagulopathy among trauma and/or sepsis patients