Today, there is a wealth of large databases describing the health and demographics of different populations. The availability of data alone, however, is not sufficient to understand the underlying causes and life course of common diseases and disorders. We apply modern statistical and epidemiological methods to extract and create new data and information from these data sources. To fully understand how the information can answer our various research questions, we need expertise from a spectrum of research disciplines. These include international experts in biostatistics, data science and data management, epidemiology, public health, clinical expertise, biology and genetics.