Neuroimmunology of cancer – Sébastien Talbot

Our neuroimmunology lab investigates the interaction between sensory neurons and immune responses in cancer. Our research aims to demonstrate how sensory neurons can influence tumor growth through immune system modulation. We explore therapies that inhibit these neurons or their downstream effects to enhance the immune response against tumors. Our ultimate goal is to develop novel cancer treatments that target neuro-immune interactions.

Publications

All publications from group members

Journal article: NATURE REVIEWS CANCER. 2025;:573-589
Neuro-immune cross-talk in cancer
Amit M; Eichwald T; Roger A; Anderson J; Chang A; Vermeer PD; Dixon KO; Scheff NN; Talbot S
Journal article: BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 2025;1871(5):167824
Aminolevulinate/iron exposure elicited Nrf-2-mediated cytoprotection in DARS2 deficient fibroblasts with impaired energy and antioxidant metabolisms.
Huang W-L; Eichwald T; Stover A; Gazanfari M; Schwartz PH; Latini A; Abdenur JE
Journal article: BRAIN SCIENCES. 2025;15(6):646
Pain Hypersensitivity and Increased Urinary Tetrahydrobiopterin Levels in Mice Submitted to High-Fat Diet
Eichwald T; Scheffer DDL; Barros L; Solano A; Menegassi VDS; Staats Pires AC; Spivakoski CS; Da Silva RA; Gaspar JM; Ronsoni MF; Latini A
Editorial comment: NATURE REVIEWS IMMUNOLOGY. 2025;25(5):318
Macrophages promote nerve growth in both tumours and spinal cord
Baleviciute A; Talbot S
Editorial comment: CANCER CELL. 2025;43(1):1-5
Integrating priorities at the intersection of cancer and neuroscience
Hwang WL; Perrault EN; Birbrair A; Mattson BJ; Gutmann DH; Mabbott DJ; Cukierman E; Repasky EA; Sloan EK; Zong H; Demir IE; Saloman JL; Borniger JC; Hu J; Dietrich J; Breunig JJ; Cifcibas K; Kasm KAA; Valiente M; Wintermark M; Acharya MM; Scheff NN; D'Silva NJ; Vermeer PD; Wong RJ; Talbot S; Hervey-Jumper SL; Wang TC; Ye Y; Pan Y; Bunimovich YL; Amit M
Article: CELL REPORTS. 2024;43(12):115045
Cytokines reprogram airway sensory neurons in asthma
Crosson T; Bhat S; Wang J-C; Salaun C; Fontaine E; Roversi K; Herzog H; Rafei M; Blunck R; Talbot S
Review: CURRENT OPINION IN IMMUNOLOGY. 2024;91:102507
Decoding the neuroimmune axis in the atopic march: mechanisms and implications
Brabenec L; Gupta S; Eichwald T; Rafei M; Talbot S
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2024;12(11):e009962
Morphine treatment restricts response to immunotherapy in oral squamous cell carcinoma
Mcilvried LA; Martel Matos AA; Yuan MM; Atherton MA; Obuekwe F; Nilsen ML; Nikpoor AR; Talbot S; Bruno TC; Taggart DN; Johnson LK; Ferris RL; Zandberg DP; Scheff NN
Review: NATURE REVIEWS DRUG DISCOVERY. 2024;23(10):780-796
Targeting the peripheral neural-tumour microenvironment for cancer therapy
Yaniv D; Mattson B; Talbot S; Gleber-Netto FO; Amit M
Preprint: BIORXIV. 2024;BIORXIV
Cytokines reprogram airway sensory neurons in asthma.
Crosson T; Bhat S; Wang J-C; Salaun C; Fontaine E; Roversi K; Herzog H; Rafei M; Blunck R; Talbot S
Preprint: BIORXIV. 2024;BIORXIV
TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION.
Restaino AC; Ahmadi M; Nikpoor AR; Walz A; Balood M; Eichwald T; Talbot S; Vermeer PD
Preprint: BIORXIV. 2024;BIORXIV
NOCICEPTOR NEURONS CONTROL POLLUTION-MEDIATED NEUTROPHILIC ASTHMA.
Wang J-C; Crosson T; Nikpoor AR; Gupta S; Rafei M; Talbot S
Journal article: ANESTHESIA AND ANALGESIA. 2024;140(5):1073-1082
Detection and Evaluation of Procalcitonin Variants As Diagnostic Tools in Systemic Inflammation
Kintrup S; Brabenec L; Zurek-Leffers F-M; Hellenthal KEM; Cyran L; Meybohm P; Gerke V; Wagner N-M
Editorial comment: TRENDS IN IMMUNOLOGY. 2024;45(8):574-576
Aching to defend: spleen innervation drives humoral immunity
Eichwald T; Talbot S
Review: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2024;154(1):11-19
Interactions between skin-resident dendritic and Langerhans cells and pain-sensing neurons.
Wilcox NC; Taheri G; Halievski K; Talbot S; Silva JR; Ghasemlou N
Preprint: BIORXIV. 2024;BIORXIV
BASOPHILS ACTIVATE PRURICEPTOR-LIKE VAGAL SENSORY NEURONS.
Wang J-C; Nikpoor AR; Crosson T; Kaufmann E; Rafei M; Talbot S
Article: BIORXIV. 2024;:2023.10.18.562990
Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a male mouse model of head-and-neck cancer.
Barr J; Walz A; Restaino AC; Amit M; Barclay SM; Vichaya EG; Spanos WC; Dantzer R; Talbot S; Vermeer PD
Journal article: CANCER RESEARCH. 2024;84(7_Supplement):sy31-02-sy31-02
Abstract SY31-02: Nociceptor neurons control anti-tumor immunity
Eichwald T; Balood M; Ahmadi M; Roversi K; Wong D; Mandl J; Rafei M; Ghasemlou N; Vermeer P; Amit M; Talbot S
Editorial comment: CANCER DISCOVERY. 2024;14(4):669-673
Next Directions in the Neuroscience of Cancers Arising outside the CNS
Amit M; Anastasaki C; Dantzer R; Demir IE; Deneen B; Dixon KO; Egeblad M; Gibson EM; Hervey-Jumper SL; Hondermarck H; Magnon C; Monje M; Na'ara S; Pan Y; Repasky EA; Scheff NN; Sloan EK; Talbot S; Tracey KJ; Trotman LC; Valiente M; Van Aelst L; Venkataramani V; Venkatesh HS; Vermeer PD; Winkler F; Wong RJ; Gutmann DH; Borniger JC
Journal article: MOLECULAR GENETICS AND METABOLISM. 2024;141(4):108187
Bioenergetics and antioxidant status in human TFAM deficient fibroblasts
Gazanfari M; Huang W-L; Eichwald T; Stover A; Schwartz PH; Latini A; Abdenur J
Article: CANCER SCIENCE. 2024;115(4):1102-1113
An engineered Accum-E7 protein-based vaccine with dual anti-cervical cancer activity.
Bikorimana J-P; Abusarah J; Gonçalves M; Farah R; Saad W; Talbot S; Stanga D; Beaudoin S; Plouffe S; Rafei M
Review: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2024;153(4):924-938
Navigating the blurred path of mixed neuroimmune signaling
Gupta S; Viotti A; Eichwald T; Roger A; Kaufmann E; Othman R; Ghasemlou N; Rafei M; Foster SL; Talbot S
Article: ISCIENCE. 2024;27(3):109248
A1-reprogrammed mesenchymal stromal cells prime potent antitumoral responses.
Gonçalves MP; Farah R; Bikorimana J-P; Abusarah J; El-Hachem N; Saad W; Talbot S; Stanga D; Beaudoin S; Plouffe S; Rafei M
Journal article: NEUROTOXICOLOGY. 2023;97:12-24
ALDH2 inhibition by lead and ethanol elicits redox imbalance and mitochondrial dysfunction in SH-SY5Y human neuroblastoma cell line: Reversion by Alda-1.
Deza-Ponzio R; Albrecht PA; Fernandez-Hubeid LE; Eichwald T; Cejas RB; Garay YC; Rivera-Meza M; Latini A; Irazoqui FJ; Virgolini MB
Journal article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2023;11(1):31
A model of porcine polymicrobial septic shock
Zurek-Leffers FM; Lehmann F; Brabenec L; Kintrup S; Hellenthal KEM; Mersjann K; Kneifel F; Hessler M; Arnemann P-H; Kampmeier T-G; Ertmer C; Kellner P; Wagner N-M
Article: SCIENCE ADVANCES. 2023;9(19):eade4443
Functional neuronal circuits promote disease progression in cancer
Restaino AC; Walz A; Vermeer SJ; Barr J; Kovacs A; Fettig RR; Vermeer DW; Reavis H; Williamson CS; Lucido CT; Eichwald T; Omran DK; Jung E; Schwartz LE; Bell M; Muirhead DM; Hooper JE; Spanos WC; Drapkin R; Talbot S; Vermeer PD
Editorial comment: IMMUNITY. 2023;56(5):906-908
Decoding nociceptor-DC dialogues
Crosson T; Talbot S
Journal article: ANTIOXIDANTS. 2023;12(5):1037
Tetrahydrobiopterin: Beyond Its Traditional Role as a Cofactor.
Eichwald T; da Silva LDB; Staats Pires AC; Niero L; Schnorrenberger E; Filho CC; Espíndola G; Huang W-L; Guillemin GJ; Abdenur JE; Latini A
Article: CELLS. 2023;12(8):1189
A Preliminary Study of Mild Heat Stress on Inflammasome Activation in Murine Macrophages
Foster SL; Dutton AJ; Yerzhan A; March LB; Barry K; Seehus CR; Huang X; Talbot S; Woolf CJ
Journal article: MOLECULAR GENETICS AND METABOLISM. 2023;138(3):107440
ENHANCED ENERGY METABOLISM AND CYTOPROTECTION IN AMINOLEVULINATE/IRON-EXPOSED DARS2 DEFICIENT FIBROBLASTS
Latini A; Huang W-L; Eichwald T; Stover A; Schwartz P; Abdenur J
Journal article: ANTIOXIDANTS. 2023;12(3):554
Anti-Inflammatory Effect of Caffeine on Muscle under Lipopolysaccharide-Induced Inflammation
Eichwald T; Solano AF; Souza J; de Miranda TB; Carvalho LB; Sanna PLDS; da Silva RAF; Latini A
Journal article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(3):e163735
A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents
He S; Zambelli VO; Sinharoy P; Brabenec L; Bian Y; Rwere F; Hell RCR; Neto BS; Hung B; Yu X; Zhao M; Luo Z; Wu C; Xu L; Svensson KJ; McAllister SL; Stary CM; Wagner N-M; Zhang Y; Gross ER
Article: ISCIENCE. 2022;25(12):105537
The CIt protocol: A blueprint to potentiate the immunogenicity of immunoproteasome-reprogrammed mesenchymal stromal cells
Bikorimana J-P; El-Hachem N; Abusarah J; Eliopoulos N; Talbot S; Shammaa R; Rafei M
Article: NATURE. 2022;611(7935):405-412
Nociceptor neurons affect cancer immunosurveillance
Balood M; Ahmadi M; Eichwald T; Ahmadi A; Majdoubi A; Roversi K; Roversi K; Lucido CT; Restaino AC; Huang S; Ji L; Huang K-C; Semerena E; Thomas SC; Trevino AE; Merrison H; Parrin A; Doyle B; Vermeer DW; Spanos WC; Williamson CS; Seehus CR; Foster SL; Dai H; Shu CJ; Rangachari M; Thibodeau J; Del RSV; Drapkin R; Rafei M; Ghasemlou N; Vermeer PD; Woolf CJ; Talbot S
Journal article: FREE RADICAL BIOLOGY AND MEDICINE. 2022;192:85
Tetrahydrobiopterin metabolism is impaired in chemically-induced, idiopathic and genetic mitochondrial deficiencies
Cruz L; Pasa T; Scheffer D; Eichwald T; Stover A; Schwartz P; Huang W-L; Walz R; De Paul AL; Abdenur J; Latini A
Journal article: LIFE SCIENCES. 2022;307:120889
Procalcitonin mediates vascular dysfunction in obesity
Brabenec L; Hellenthal KEM; Mueller M; Kintrup S; Zurek-Leffers F; Kardell M; Otto M; Wagner N-M
Article: BIO-PROTOCOL. 2022;12(19):e4527
LIST: A Newly Developed Laser-assisted Cell Bioprinting Technology
Roversi K; Orimi HE; Erfanian M; Talbot S; Boutopoulos C
Journal article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022;206(4):488-500
Targeting Procalcitonin Protects Vascular Barrier Integrity
Brabenec L; Mueller M; Hellenthal KEM; Karsten OS; Pryvalov H; Otto M; Holthenrich A; Matos ALL; Weiss R; Kintrup S; Hessler M; Dell'Aquila A; Thomas K; Nass J; Margraf A; Nottebaum AF; Rossaint J; Zarbock A; Vestweber D; Gerke V; Wagner N-M
Article: CELLS. 2022;11(15):2263
CD146 Defines a Mesenchymal Stromal Cell Subpopulation with Enhanced Suppressive Properties
Bikorimana J-P; Saad W; Abusarah J; Lahrichi M; Talbot S; Shammaa R; Rafei M
Article: AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. 2022;67(1):e1-18
Advancing Lung Immunology Research An Official American Thoracic Society Workshop Report
Rahimi RA; Cho JL; Jakubzick CV; Khader SA; Lambrecht BN; Lloyd CM; Molofsky AB; Talbot S; Bonham CA; Drake WP; Sperling AI; Singer BD
Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2022;(184)
Teasing Out the Interplay Between Natural Killer Cells and Nociceptor Neurons
Ahmadi A; Balood M; Roversi K; Ahmadi M; Rafei M; Talbot S
Journal article: CELLS. 2022;11(12):1935
Regulation and Dysregulation of Endothelial Permeability during Systemic Inflammation
Hellenthal KEM; Brabenec L; Wagner N-M
Article: CELLS. 2022;11(11):1816
LSD1 Inhibition Enhances the Immunogenicity of Mesenchymal Stromal Cells by Eliciting a dsRNA Stress Response
Mardani F; Saad W; El-Hachem N; Bikorimana J-P; Kurdi M; Shammaa R; Talbot S; Rafei M
Article: BIOELECTRONIC MEDICINE. 2022;8(1):7
Anatomical differences in nociceptor neurons sensitivity.
Crosson T; Talbot S
Article: SMALL. 2022;18(14):e2103364
Nanophotonics Enable Targeted Photothermal Silencing of Nociceptor Neurons
Roversi K; Tabatabaei M; Desjardins-Lecavalier N; Balood M; Crosson T; Costantino S; Griffith M; Talbot S; Boutopoulos C
Article: CELL REPORTS MEDICINE. 2022;3(3):100534
Promoting antigen escape from dendritic cell endosomes potentiates anti-tumoral immunity
Bikorimana J-P; Salame N; Beaudoin S; Balood M; Crosson T; Abusarah J; Talbot S; Lobenberg R; Plouffe S; Rafei M
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(2):ab12
Nociceptor Neurons Control Pollution-exacerbated Asthma
Crosson T; Eichwald T; Roversi K; Ahmadi M; Ahmadi A; Balood M; Talbot S
Journal article: NEUROTOXICITY RESEARCH. 2022;40(1):276-285
Protective Effects of Probucol on Different Brain Cells Exposed to Manganese
da Silva EB; Eichwald T; Glaser V; Varela KG; Baptistella AR; de Carvalho D; Remor AP
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(2):ab132
Nociceptor neurons protect from allergen-induced anaphylaxis
Eichwald T; Wang J-C; Poirier F; Crosson T; Ahmadi M; Balood M; Ahmadi A; Roversi K; Talbot S
Article: METHODS IN MOLECULAR BIOLOGY. 2022;2506:297-314
Analysis of Airway Vagal Neurons.
Wang J-C; Crosson T; Talbot S
Article: JCI INSIGHT. 2021;6(24):e148510
Nociceptor neurons promote IgE class switch in B cells
Mathur S; Wang J-C; Seehus CR; Poirier F; Crosson T; Hsieh Y-C; Doyle B; Lee S; Woolf CJ; Foster SL; Talbot S
Article: CELL REPORTS MEDICINE. 2021;2(12):100455
Engineering immunoproteasome-expressing mesenchymal stromal cells: A potent cellular vaccine for lymphoma and melanoma in mice
Abusarah J; Khodayarian F; El-Hachem N; Salame N; Olivier M; Balood M; Roversi K; Talbot S; Bikorimana J-P; Chen J; Jolicoeur M; Trudeau L-E; Kamyabiazar S; Annabi B; Robert F; Pelletier J; El-Kadiry A-E; Shammaa R; Rafei M
Journal article: LIFE SCIENCES. 2021;284:119925
Development of heart failure with preserved ejection fraction in type 2 diabetic mice is ameliorated by preserving vascular function
Otto M; Brabenec L; Mueller M; Kintrup S; Hellenthal KEM; Holtmeier R; Steinbuch SC; Karsten OS; Pryvalov H; Rossaint J; Gross ER; Wagner N-M
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2021;178(19):3905-3923
Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker
Tochitsky I; Jo S; Andrews N; Kotoda M; Doyle B; Shim J; Talbot S; Roberson D; Lee J; Haste L; Jordan SM; Levy BD; Bean BP; Woolf CJ
Journal article: BIOMOLECULES. 2021;11(10):1401
TRP Channels as Sensors of Aldehyde and Oxidative Stress
Hellenthal KEM; Brabenec L; Gross ER; Wagner N-M
Article: MICROMACHINES. 2021;12(8):865
Bioprinting of Adult Dorsal Root Ganglion (DRG) Neurons Using Laser-Induced Side Transfer (LIST)
Roversi K; Ebrahimi Orimi H; Falchetti M; Lummertz da Rocha E; Talbot S; Boutopoulos C
Journal article: PLANTA MEDICA. 2021;87(08):611-619
BNO 1095, a Standardized Dry Extract from the Fruits of Vitex agnus-castus , Impairs Angiogenesis-related Endothelial Cell Functions In Vitro
Bischoff-Kont I; Brabenec L; Ingelfinger R; Nausch B; Fuerst R
Preprint: RESEARCH SQUARE. 2021
Nociceptor neurons impair cancer immunosurveillance
Talbot S; Balood M; Ahmadi M; Eichwald T; Majdoubi A; Merrison H; Parrin A; Doyle B; Lucido C; Vermeer D; Huang S; Ji L; Dai H; Shu C; Roversi K; Thomas S; Seehus C; Foster S; Ahmadi A; Rafei M; Rangachari M; Thibodeau J; Ghasemlou N; Rincon SD; Drapkin R; Vermeer P; Woolf C
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;147(6):2330-2342
FcεR1-expressing nociceptors trigger allergic airway inflammation
Crosson T; Wang J-C; Doyle B; Merrison H; Balood M; Parrin A; Pascal M; Mindt BC; Seehus CR; Ozcan A; Huang X; Semenara E; Lai NYY; Majdoubi A; Abdulnour R-EE; Rajchgot T; Rafei M; Foster SL; Thibodeau J; Fritz JH; Levy BD; Woolf CJ; Talbot S
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;147(2):ab149
Nociceptor Neurons Control Pollution-exacerbated Asthma
Wang J-C; Crosson T; Eichwald T; Roversi K; Ahmadi M; Balood M; Talbot S
Journal article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;147(2):ab54
Vagal sensory neurons sense allergens to regulate Type 2 inflammation
Crosson T; WANG J-C; Roversi K; Eichwald T; Balood M; Ahmadi M; Talbot S
Article: NATURE BIOTECHNOLOGY. 2021;39(2):179-185
Epineural optogenetic activation of nociceptors initiates and amplifies inflammation
Michoud F; Seehus C; Schoenle P; Brun N; Taub D; Zhang Z; Jain A; Furfaro I; Akouissi O; Moon R; Meier P; Galan K; Doyle B; Tetreault M; Talbot S; Browne LE; Huang Q; Woolf CJ; Lacour SP
Review: FRONTIERS IN IMMUNOLOGY. 2021;12:759679
Neuro-Immunity and Gut Dysbiosis Drive Parkinson's Disease-Induced Pain
Roversi K; Callai-Silva N; Roversi K; Griffith M; Boutopoulos C; Prediger RD; Talbot S
Journal article: ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH. 2020;27(36):45874-45882
Exposure to the herbicide 2,4-dichlorophenoxyacetic acid impairs mitochondrial function, oxidative status, and behavior in adult zebrafish
Thiel NA; Sachett A; Schneider SE; Garbinato C; Decui L; Eichwald T; Conterato GMM; Latini A; Piato A; Siebel AM
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2020;145(6):1693-1696.e4
Vagal sensory neurons drive mucous cell metaplasia
Talbot S; Doyle B; Huang J; Wang J-C; Ahmadi M; Roberson DP; Yekkirala A; Foster SL; Browne LE; Bean BP; Levy BD; Woolf CJ
Preprint: BIORXIV. 2020
Tumor-infiltrating nerves create an electro-physiologically active microenvironment and contribute to treatment resistance
Kovacs A; Vermeer D; Madeo M; Reavis H; Vermeer S; Williamson C; Rickel A; Stamp J; Lucido C; Cain J; Bell M; Morgan M; Yoon J-Y; Mitchell M; Tulina N; Stuckelberger S; Budina A; Omran D; Jung E; Schwartz L; Eichwald T; Hong Z; Weimer J; Hooper J; Godwin A; Talbot S; Drapkin R; Vermeer P
Article: FRONTIERS IN PHARMACOLOGY. 2020;11:237
A Novel Sulfonyl-Based Small Molecule Exhibiting Anti-cancer Properties
El-Kadiry AE-H; Abusarah J; Cui YE; El-Hachem N; Hammond-Martel I; Wurtele H; Thomas S; Ahmadi M; Balood M; Talbot S; Rafei M
Editorial comment: FRONTIERS IN NEUROSCIENCE. 2020;14:56
Editorial: Obesity and Diabetes: Implications for Brain-Immunometabolism
Gaspar JM; Talbot S; Latini A
Review: FRONTIERS IN HUMAN NEUROSCIENCE. 2020;14:181
Neuro-Immunity Controls Obesity-Induced Pain
Eichwald T; Talbot S
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:1953
Lack of the E3 Ubiquitin Ligase March1 Affects CD8 T Cell Fate and Exacerbates Insulin Resistance in Obese Mice
Majdoubi A; Lee JS; Kishta OA; Balood M; Moulefera MA; Ishido S; Talbot S; Cheong C; Alquier T; Thibodeau J
Preprint: SSRN ELECTRONIC JOURNAL. 2020
Nociceptor Neurons Decrease Cancer Immunosurveillance
Balood M; Ahmadi M; Majdoubi A; Eichwald T; Merrison H; Parrin A; Doyle B; Vermeer D; Wang C-C; Thanawala M; Roversi K; Thomas SC; Seehus CR; Foster SL; Latini A; Rafei M; Rangachari M; Del Rincon S; Shu CJ; Drapkin R; Thibodeau J; Woolf CJ; Vermeer PD; Talbot S
Journal article: REVISTA BRASILEIRA DE SAÚDE OCUPACIONAL. 2020;45:e1
Ação interinstitucional e participação social na atuação da Comissão Intersetorial de Saúde do Trabalhador e da Trabalhadora: relato de caso
Steffani JA; Wames MMM; Eichwald T; Dallacosta FM; Rossoni C; Cetolin SF
Article: JOURNAL OF IMMUNOLOGY. 2019;203(11):2887-2898
Downregulation of MHC Class II by Ubiquitination Is Required for the Migration of CD206⁺ Dendritic Cells to Skin-Draining Lymph Nodes
Majdoubi A; Lee JS; Balood M; Sabourin A; DeMontigny A; Kishta OA; Moulefera MA; Galbas T; Yun TJ; Talbot S; Ishido S; Cheong C; Thibodeau J
Article: ELIFE. 2019;8:e48118
Novel charged sodium and calcium channel inhibitor active against neurogenic inflammation
Lee S; Jo S; Talbot S; Zhang H-XB; Kotoda M; Andrews NA; Puopolo M; Liu PW; Jacquemont T; Pascal M; Heckman LM; Jain A; Lee J; Woolf CJ; Bean BP
Journal article: JOURNAL OF INTERNAL MEDICINE. 2019;286(3):268-289
Profiling of how nociceptor neurons detect danger - new and old foes
Crosson T; Roversi K; Balood M; Othman R; Ahmadi M; Wang J-C; Pereira PJS; Tabatabaei M; Couture R; Eichwald T; Latini A; Prediger RD; Rangachari M; Seehus CR; Fosters SL; Talbot S
Corrigendum: NATURE. 2019;572(7769):E18
Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
Cronin SJF; Seehus C; Weidinger A; Talbot S; Reissig S; Seifert M; Pierson Y; McNeill E; Longhi MS; Turnes BL; Kreslavsky T; Kogler M; Hoffmann D; Ticevic M; da Luz Scheffer D; Tortola L; Cikes D; Jais A; Rangachari M; Rao S; Paolino M; Novatchkova M; Aichinger M; Barrett L; Latremoliere A; Wirnsberger G; Lametschwandtner G; Busslinger M; Zicha S; Latini A; Robson SC; Waisman A; Andrews N; Costigan M; Channon KM; Weiss G; Kozlov AV; Tebbe M; Johnsson K; Woolf CJ; Penninger JM
Journal article: REGULATORY TOXICOLOGY AND PHARMACOLOGY. 2019;104:98-107
Sex differences in subacute manganese intoxication: Oxidative parameters and metal deposition in peripheral organs of adult Wistar rats
Richter Schmitz CR; Eichwaldd T; Branco Flores MV; Varela KG; Mantovani A; Steffani JA; Glaser V; de Carvalho D; Remor AP
Journal article: PHYSIOLOGY & BEHAVIOR. 2019;204:309-323
Epigenetic modifications induced by exercise: Drug-free intervention to improve cognitive deficits associated with obesity
Barros L; Eichwald T; Solano AF; Scheffer D; da Silva RA; Gaspar JM; Latini A
Article: STEM CELL REPORTS. 2019;12(1):29-41
Neurite Collapse and Altered ER Ca²⁺ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation
Korecka JA; Talbot R; Osborn TM; de Leeuw SM; Levy SA; Ferrari EJ; Moskites A; Atkinson E; Jodelka FM; Hinrich AJ; Hastings ML; Woolf CJ; Hallett PJ; Isacson O
Editorial comment: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY. 2019;2019:2715326-2
Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration
Latini A; Pereira PJS; Couture R; Campos MM; Talbot S
Review: FRONTIERS IN NEUROSCIENCE. 2019;13:25
Neurons and Microglia; A Sickly-Sweet Duo in Diabetic Pain Neuropathy
Rajchgot T; Thomas SC; Wang J-C; Ahmadi M; Balood M; Crosson T; Dias JP; Couture R; Claing A; Talbot S
Journal article: FRONTIERS IN NEUROSCIENCE. 2019;13:323
Deep Brain Stimulation for Obesity: A Review and Future Directions
Formolo DA; Gaspar JM; Melo HM; Eichwald T; Zepeda RJ; Latini A; Okun MS; Walz R
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:3115
Endogenous T Cell Receptor Rearrangement Represses Aggressive Central Nervous System Autoimmunity in a TcR-Transgenic Model on the Non-Obese Diabetic Background
Yeola AP; Doss PMIA; Baillargeon J; Akbar I; Mailhot B; Balood M; Talbot S; Anderson AC; Lacroix S; Rangachari M
Journal article: REVISTA INTERDISCIPLINAR DE ESTUDOS EM SAÚDE. 2018;7(2):193-210
INTOXICAÇÃO SUBAGUDA AO MANGANÊS EM RATOS WISTAR ADULTOS: AVALIAÇÃO DE PARÂMETROS OXIDATIVOS NO SNC E DEPOSIÇÃO DO METAL EM DIFERENTES TECIDOS
Flores MVB; Eichwald T; Mantovani A; Glaser V; Schimitz CRR; Rossoni C; Steffani JA; Perinetto D; Carvalho D; Remor AP
Article: NATURE. 2018;563(7732):564-568
The metabolite BH4 controls T cell proliferation in autoimmunity and cancer
Cronin SJF; Seehus C; Weidinger A; Talbot S; Reissig S; Seifert M; Pierson Y; McNeill E; Longhi MS; Turnes BL; Kreslavsky T; Kogler M; Hoffmann D; Ticevic M; Scheffer DDL; Tortola L; Cikes D; Jais A; Rangachari M; Rao S; Paolino M; Novatchkova M; Aichinger M; Barrett L; Latremoliere A; Wirnsberger G; Lametschwandtner G; Busslinger M; Zicha S; Latini A; Robson SC; Waisman A; Andrews N; Costigan M; Channon KM; Weiss G; Kozlov AV; Tebbe M; Johnsson K; Woolf CJ; Penninger JM
Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;140(2):447-453.e3
Substance P activates Mas-related G protein-coupled receptors to induce itch
Azimi E; Reddy VB; Seadi Pereira PJ; Talbot S; Woolf CJ; Lerner EA
Review: FRONTIERS IN IMMUNOLOGY. 2017;8:1463
Sense and Immunity: Context-Dependent Neuro-Immune Interplay
Foster SL; Seehus CR; Woolf CJ; Talbot S
Article: JCI INSIGHT. 2016;1(16):e89362
Dual action of neurokinin-1 antagonists on Mas-related GPCRs
Azimi E; Reddy VB; Shade K-TC; Anthony RM; Talbot S; Pereira PJS; Lerner EA
Article: CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY. 2016;94(7):752-757
Beneficial effects of kinin B1 receptor antagonism on plasma fatty acid alterations and obesity in Zucker diabetic fatty rats
Talbot S; Dias JP; El Midaoui A; Couture R
Review: ANNUAL REVIEW OF IMMUNOLOGY. 2016;34:421-447
Neuroimmunity: Physiology and Pathology
Talbot S; Foster SL; Woolf CJ
Article: BIOELECTRONIC MEDICINE. 2016;3:18-28
Neuronal Circuits Modulate Antigen Flow Through Lymph Nodes.
Hanes WM; Olofsson PS; Talbot S; Tsaava T; Ochani M; Imperato GH; Levine YA; Roth J; Pascal MA; Foster SL; Wang P; Woolf C; Chavan SS; Tracey KJ
Article: JOURNAL OF NEUROSCIENCE. 2015;35(49):16272-16281
GRPR/PI3Kγ: Partners in Central Transmission of Itch
Pereira PJS; Machado GDB; Danesi GM; Canevese FF; Reddy VB; Pereira TCB; Bogo MR; Cheng Y-C; Laedermann C; Talbot S; Lerner EA; Campos MM
Article: NEURON. 2015;87(2):341-354
Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation
Talbot S; Abdulnour R-EE; Burkett PR; Lee S; Cronin SJF; Pascal MA; Laedermann C; Foster SL; Tran JV; Lai N; Chiu IM; Ghasemlou N; DiBiase M; Roberson D; Von Hehn C; Agac B; Haworth O; Seki H; Penninger JM; Kuchroo VK; Bean BP; Levy BD; Woolf CJ
Article: J DIABETES METAB. 2015;6(6):1-7
Effects of Alpha-Lipoic Acid on Oxidative Stress and Kinin Receptor Expression in Obese Zucker Diabetic Fatty Rats.
Midaoui AE; Talbot S; Lahjouji K; Dias JP; Fantus IG; Couture R
Editorial comment: IMMUNITY. 2015;42(3):403-405
CNS Injury: IL-33 Sounds the Alarm
Foster SL; Talbot S; Woolf CJ
Article: BEHAVIOURAL BRAIN RESEARCH. 2013;241:17-26
Brain kinin B₁ receptor contributes to the onset of stereotypic nocifensive behavior in rat
Gariepy HDB; Talbot S; Senecal J; Couture R
Article: JOURNAL OF NEUROINFLAMMATION. 2012;9:214
Activation of kinin B1 receptor evokes hyperthermia through a vagal sensory mechanism in the rat
Talbot S; Gariepy HDB; Saint-Denis J; Couture R
Article: EXPERIMENTAL NEUROLOGY. 2012;234(2):373-381
Emerging role of microglial kinin B1 receptor in diabetic pain neuropathy
Talbot S; Couture R
Article: TOXICOLOGY. 2012;293(1-3):125-131
An ex vivo approach to the differential parenchymal responses induced by cigarette whole smoke and its vapor phase
Lin JC-J; Roy J-P; Verreault J; Talbot S; Cote F; Couture R; Morin A
Article: JOURNAL OF NEUROINFLAMMATION. 2012;9:16
Activation of TRPV1 by capsaicin induces functional Kinin B₁ receptor in rat spinal cord microglia
Talbot S; Dias JP; Lahjouji K; Bogo MR; Campos MM; Gaudreau P; Couture R
Article: PLOS ONE. 2012;7(3):e33864
Ocular Application of the Kinin B₁ Receptor Antagonist LF22-0542 Inhibits Retinal Inflammation and Oxidative Stress in Streptozotocin-Diabetic Rats
Pouliot M; Talbot S; Senecal J; Dotigny F; Vaucher E; Couture R
Article: PEPTIDES. 2011;32(7):1447-1456
Cigarette smoke-induced kinin B1 receptor promotes NADPH oxidase activity in cultured human alveolar epithelial cells
Talbot S; Lin JC-J; Lahjouji K; Roy J-P; Senecal J; Morin A; Couture R
Article: PEPTIDES. 2010;31(10):1940-1945
Mechanism of cigarette smoke-induced kinin B₁ receptor expression in rat airways
Lin JC-J; Talbot S; Lahjouji K; Roy J-P; Senecal J; Couture R; Morin A
Article: PLOS ONE. 2010;5(9):e12622
Kinin B₁ Receptor Enhances the Oxidative Stress in a Rat Model of Insulin Resistance: Outcome in Hypertension, Allodynia and Metabolic Complications
Dias JP; Talbot S; Senecal J; Carayon P; Couture R
Article: JOURNAL OF NEUROINFLAMMATION. 2010;7(1):36
Key role for spinal dorsal horn microglial kinin B₁ receptor in early diabetic pain neuropathy
Talbot S; Chahmi E; Dias JP; Couture R
Article: JOURNAL OF NEUROINFLAMMATION. 2009;6:11
Cellular localization of kinin B₁ receptor in the spinal cord of streptozotocin-diabetic rats with a fluorescent [N^α-Bodipy]-des-Arg⁹-bradykinin
Talbot S; Theberge-Turmel P; Liazoghli D; Senecal J; Gaudreau P; Couture R
Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2008;52(3):278-285
Effects of angiotensin-1 converting enzyme inhibition on oxidative stress and bradykinin receptor expression during doxorubicin-induced cardiomyopathy in rats
Richard C; Lauzier B; Delemasure S; Talbot S; Ghibu S; Collin B; Senecal J; Menetrier F; Vergely C; Couture R; Rochette L
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2008;589(1-3):66-72
Blockade of sensory abnormalities and kinin B₁ receptor expression by N-Acetyl-L-Cysteine and ramipril in a rat model of insulin resistance
Ismael MA; Talbot S; Carbonneau CL; Beausejour CM; Couture R
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2008;154(1):136-143
Retinal plasma extravasation in streptozotocin-diabetic rats mediated by kinin B₁ and B₂ receptors
Abdouh M; Talbot S; Couture R; Hassessian HM
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2007;557(2-3):115-123
Differential regulation of the signaling and trafficking of the two prostaglandin D₂ receptors, prostanoid DP receptor and CRTH2
Gallant MA; Slipetz D; Hamelin E; Rochdi MD; Talbot S; de Brum-Fernandes AJ; Parent J-L
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Karolinska Intitutet, Physiology and Pharmacology, B5, Solnavägen 9, Solna, 171 65, Sweden

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Karolinska Development (Sweden), Physiology and Pharmacology, Solnavägen 9, Solna, 171 65, Sweden