Sepsis and microcirculation – Sara Tehrani's research group

Publications

All publications from group members

• Review: JOURNAL OF VASCULAR RESEARCH. 2025;:1-16

  Noninvasive Bedside Approaches for Assessing Microvascular Dysfunction

  Widaeus J; Fredriksson I; Tehrani S
• Article: TH OPEN. 2025;09:a26469016

  Risk Factors for Recurrent Thrombosis in Patients with Antiphospholipid Syndrome-A Single-Centre Cohort Study

  Karandyszowska N; Faustini F; Alagunduz H; Widaeus J; Carlens F; Jensen A-L; Oksanen A; Magnusson M; Gunnarsson I; Svenungsson E; Antovic A; Bruzelius M
• Article: JACC: CASE REPORTS. 2025;30(14):103611

  Transient Coronary Microvascular Dysfunction in Septic Shock.

  Lörstad S; Tehrani S; Ekenbäck C; Shahgaldi K; Åstrand P; Aspberg J; Persson J
• Article: JOURNAL OF INTENSIVE CARE MEDICINE. 2025;40(3):320-330

  Development of an Extended Cardiovascular SOFA Score Component Reflecting Cardiac Dysfunction with Improved Survival Prediction in Sepsis: An Exploratory Analysis in the Sepsis and Elevated Troponin (SET) Study

  Lorstad S; Wang Y; Tehrani S; Shekarestan S; Astrand P; Gille-Johnson P; Jernberg T; Persson J
• Article: ATHEROSCLEROSIS. 2024;390:117335

  Use of heated tobacco products (IQOS) causes an acute increase in arterial stiffness and platelet thrombus formation

  Lyytinen G; Melnikov G; Brynedal A; Anesater E; Antoniewicz L; Blomberg A; Wallen H; Bosson JA; Hedman L; Tehrani S; Lundback M
• Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2023;208(12):1293-1304

  High-Dose Inhaled Nitric Oxide in Acute Hypoxemic Respiratory Failure Due to COVID-19 A Multicenter Phase II Trial

  Di Fenza R; Shetty NS; Gianni S; Parcha V; Giammatteo V; Fakhr BS; Tornberg D; Wall O; Harbut P; Lai PS; Li JZ; Paganoni S; Cenci S; Mueller AL; Houle TT; Akeju O; Bittner EA; Bose S; Scott LK; Carroll RW; Ichinose F; Hedenstierna M; Arora P; Berra L
• Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2023;78(11):2735-2742

  Effects of remdesivir on SARS-CoV-2 viral dynamics and mortality in viraemic patients hospitalized for COVID-19

  Hagman K; Hedenstierna M; Widaeus J; Arvidsson E; Hammas B; Grillner L; Jakobsson J; Gille-Johnson P; Ursing J
• Conference publication: JOURNAL OF VASCULAR RESEARCH. 2023;60(SUPP1):10-11

  Microvascular dysfunction in patients with critical COVID-19

  Tehrani S; Gille-Johnson P
• Article: AMERICAN JOURNAL OF MEDICINE. 2023;136(8):814-823.e8

  First Sampled High-Sensitive Cardiac Troponin T is Associated With One-Year Mortality in Sepsis Patients and 30-to 365-Day Mortality in Sepsis Survivors

  Lorstad S; Shekarestan S; Jernberg T; Tehrani S; Astrand P; Gille-Johnson P; Persson J
• Article: CARDIOVASCULAR TOXICOLOGY. 2023;23(7-8):255-264

  Electronic Cigarette Vaping with Nicotine Causes Increased Thrombogenicity and Impaired Microvascular Function in Healthy Volunteers: A Randomised Clinical Trial

  Lyytinen G; Brynedal A; Anesater E; Antoniewicz L; Blomberg A; Wallen H; Bosson JA; Hedman L; Mobarrez F; Tehrani S; Lundback M
• Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2023;82:1115

  THROMBOCYTOPENIA AND IMPAIRED KIDNEY FUNCTION ARE MAJOR RISK FACTORS FOR RECURRENT THROMBOSIS IN PATIENTS WITH ANTIPHOSPHOLIPID SYNDROME

  Karandyszowska N; Alagunduz H; Widaeus J; Carlens F; Warnqvist A; Magnussion M; Gunnarsson I; Svenungsson E; Bruzelius M; Antovic A
• Conference publication: EUROPEAN HEART JOURNAL. 2022;43:1486

  First sampled plasma troponin T is associated with one-year mortality in sepsis and septic shock, independent of age, gender, comorbidities, and clinically relevant biomarkers

  Loerstad S; Shekarestan S; Tehrani S; Jernberg T; Astrand P; Gille-Johnson P; Persson J
• Conference publication: 2022;:a42.2-a4a43

  PO.2.37 Risk factors for recurrent thrombosis and cause of death in patients with antiphospholipid syndrome; a Swedish cohort study

  Karandyszowska N; Alagündüz H; Oesman J; Magnusson M; Svenungsson E; Bruzelius M; Antovic A
• Article: OPEN FORUM INFECTIOUS DISEASES. 2022;9(9):ofac463

  Correlation of SARS-CoV-2 Nasopharyngeal CT Values With Viremia and Mortality in Adults Hospitalized With COVID-19

  Hagman K; Hedenstierna M; Widaeus J; Arvidsson E; Hammas B; Grillner L; Jakobsson J; Gille-Johnson P; Ursing J
• Article: CRITICAL CARE EXPLORATIONS. 2022;4(2):e0643

  Impaired Microvascular Function in Patients With Critical COVID-19

  Gille-Johnson P; Kessler I; Tehrani S
• Article: SHOCK. 2021;56(6):964-968

  Microvascular Dysfunction in Patients with Critical Covid-19, a Pilot Study

  Tehrani S; Gille-Johnson P
• Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2021;58:oa2576

  Electronic cigarettes containing nicotine increase thrombotic activity and impair microcirculation

  Lyytinen G; Bryndal A; Anesater E; Antoniewicz L; Blomberg A; Wallen H; Bosson J; Hedman L; Mobarrez F; Tehrani S; Lundback M
• Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2021;58:oa2585

  Late Breaking Abstract - Brief use of heated tobacco products causes increased arterial stiffness and thrombotic activity

  Lyytinen G; Bryndal A; Anesater E; Antoniewicz L; Blomberg A; Bosson J; Mobarrez F; Hedman L; Tehrani S; Lundback M
• Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2021;80:1184

  RISK FOR CONCOMITANT AUTOIMMUNITY IN PATIENTS WITH ANTIPHOSPHOLIPID SYNDROME; A SWEDISH COHORT STUDY

  Karandyszowska N; Oesman J; Alagunduz H; Magnusson M; Svenungsson E; Bruzelius M; Antovic A
• Conference publication: JOURNAL OF VASCULAR RESEARCH. 2021;58:4

  Microvascular Dysfunction in Patients with Severe COVID-19, A Pilot Study

  Tehrani S; Gille-Johnson P
• Article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2021;102:415-421

  Risk factors for death in adult COVID-19 patients: Frailty predicts fatal outcome in older patients

  Tehrani S; Killander A; Astrand P; Jakobsson J; Gille-Johnson P
• Article: THROMBOSIS RESEARCH. 2020;196:78-86

  High levels of endothelial and platelet microvesicles in patients with type 1 diabetes irrespective of microvascular complications

  Bergen K; Mobarrez F; Jorneskog G; Wallen H; Tehrani S
• Article: DIABETES & VASCULAR DISEASE RESEARCH. 2020;17(3):1479164120928303-147916412092830

  Skin microvascular reactivity correlates to clinical microangiopathy in type 1 diabetes: A pilot study

  Tehrani S; Bergen K; Azizi L; Jorneskog G
• Preprint: SSRN ELECTRONIC JOURNAL. 2020

  Risk Factors for Mortality in Adult and Elderly COVID-19 Patients in a Swedish University Hospital

  Tehrani S; Killander A; Åstrand P; Jakobsson J; Gille-Johnson P
• Article: THROMBOSIS RESEARCH. 2018;172:158-164

  Phosphatidylserine expressing microvesicles in relation to microvascular complications in type 1 diabetes

  Bergen K; Mobarrez F; Joerneskog G; Wallen H; Tehrani S
• Article: GROWTH HORMONE & IGF RESEARCH. 2016;29:78-82

  High-dose atorvastatin is associated with lower IGF-1 levels in patients with type 1 diabetes

  Bergen K; Brismar K; Tehrani S
• Conference publication: DIABETES. 2016;65:A548

  Circulating Microparticles in Patients with Type 1 Diabetes

  Bergen K; Mobarrez F; Jorneskog G; Wallen H; Tehrani S
• Article: THROMBOSIS AND HAEMOSTASIS. 2015;113(2):312-318

  Fibrin clot properties and haemostatic function in men and women with type 1 diabetes

  Tehrani S; Jorneskog G; Agren A; Lins P-E; Wallen H; Antovic A
• Doctoral thesis: 2013

  Hemostasis and microvascular function in type 1 diabetes : effects of treatment with statin and aspirin

  Tehrani S
• Article: DIABETES & VASCULAR DISEASE RESEARCH. 2013;10(6):483-488

  Impaired endothelium-dependent skin microvascular function during high-dose atorvastatin treatment in patients with type 1 diabetes

  Tehrani S; Mobarrez F; Lins P-E; Adamson U; Wallen HN; Jorneskog G
• Conference publication: DIABETES. 2013;62:A107

  Fibrin Clot Structure in Type 1 Diabetes: No Gender Differences but Relations to Microangiopathy

  Tehrani S; Jorneskog G; Agren A; Lins P-E; Wallen H; Antovic A
• Meeting abstract: THROMBOSIS RESEARCH. 2013;131:S72

  Gender aspects of fibrin clot structure in patients with type 1 diabetes mellitus

  Tehrani S; Wallen NH; Elgue G; Majeed K; Henriksson P; Agren A; Adamson U; Lins P-E; Jorneskog G; Antovic A
• Article: DIABETES CARE. 2012;35(2):404-408

  High-Dose Aspirin Is Required to Influence Plasma Fibrin Network Structure in Patients With Type 1 Diabetes

  Tehrani S; Antovic A; Mobarrez F; Mageed K; Lins P-E; Adamson U; Wallen HN; Jorneskog G
• Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2011;9:141

  A high dose of aspirin is required for positive influence on plasma fibrin network in patients with type 1 diabetes

  Tehrani S; Antovic A; Mobarrez F; Mageed K; Lins P-E; Adamson U; Wallen H; Jorneskog G
• Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2011;9:486

  Impaired microvascular function during atorvastatin therapy in patients with type 1 diabetes

  Tehrani S; Mobarrez F; Antovic A; Lins P-E; Adamson U; Henriksson P; Wallen H; Jorneskog G
• Conference publication: DIABETES. 2011;60:A99

  A High Dose of Aspirin Is Required for Positive Influence on Plasma Fibrin Network in Patients with Type 1 Diabetes

  Tehrani S; Antovic A; Mobarrez F; Mageed K; Lins P-E; Adamson U; Wallen H; Jorneskog G
• Article: THROMBOSIS RESEARCH. 2010;126(3):e225-e231

  Atorvastatin has antithrombotic effects in patients with type 1 diabetes and dyslipidemia

  Tehrani S; Mobarrez F; Antovic A; Santesson P; Lins P-E; Adamson U; Henriksson P; Wallen NH; Jorneskog G
• Conference publication: DIABETES. 2010;59:A287

  Impaired Glycemic Control and Skin Microvascular Reactivity during Atorvastatin Therapy in Patients with Type 1 Diabetes

  Tehrani S; Santesson P; Mobarrez F; Antovic A; Lins P-E; Adamson U; Wallen H; Jorneskog G
• Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2009;7:240

  Effects of atorvastatin on haemostasis in patients with type 1 diabetes

  Tehrani S; Mobarrez F; Antovic A; Santesson P; Lins P; Adamson U; Henriksson P; Wallen H; Jorneskog G
• Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2009;7:295

  Glycemic control is of major importance for fibrin clot structure in type 1 diabetes

  Antovic A; Mobarrez F; Tehrani S; Lins P; Adamson U; Wallen N; Jorneskog G
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Staff and contact

Group leader

• 

  Sara Tehrani

  Affiliated to Research

  E-mail sara.tehrani@ki.se

All members of the group

• Henry Ng

  Affiliated to Research

  E-mail henry.ng@ki.se
• 

  Samantha Rutherford Lörstad

  Phd Student

  E-mail samantha.rutherford.lorstad@ki.se
• 

  Sara Tehrani

  Affiliated to Research

  E-mail sara.tehrani@ki.se
• 

  Jacob Widaeus

  Phd Student

  E-mail jacob.widaeus@ki.se