Quantitative Biology of the Nucleus – Magda Bienko Group

Our research interest lies in chromosome organization and its influence on gene expression.

Illustration of human chromosomes.

Laboratory for Quantitative Biology of the Nucleus

Our research interest lies in 3D genome organization and its influence on gene expression. We are developing and applying state-of-the-art quantitative methods to measure DNA and RNA molecules at high-resolution in hundreds of single cells. We are building upon powerful methods for in situ quantification of DNA and RNA molecules, and integrating them with newly developed single-cell genomic assays to measure chromosome positioning, epigenetic states, and gene expression in a high-throughput fashion. We are also developing new sequencing-based methods for studying genome-wide chromatin localization patterns in the nucleus. We are combining technology development and experimental work with mathematical modeling and quantitative analyses to cast light on the fascinating question how two meters of DNA can fit in the microscopic volume of a cell’s nucleus.

Our group is a multicultural and multidisciplinary blend of enthusiastic people, willing to join forces and share their knowledge to make meaningful scientific advancements in a creative and collaborative work atmosphere. We welcome students from different background – including biology, biotechnology, medicine, physics, mathematics, and engineering – willing to learn an interdisciplinary and collaborative approach to fundamental questions in biology.

For more detailed information about our lab visit bienkocrosettolabs.org.

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All members of the group


Su Wang, Postdoc/Bienko group (January 2019 – April 2022)

Eleni Gelali, PhD student/Bienko group (January 2015 – February 2022)

Eleonora Oliani, Research Assistant/Bienko group (September 2020 – January 2022)

Gabriele Girelli, PhD student/Bienko group (September 2015 – December 2021)

Gesa Voigt, University of Göttingen, Germany (August 2021)

Gertjan Laenen, Taddei lab, Institut Curie, Paris, France (August 2021)

Ana Mota, PhD student/Bienko group (January 2017 – December 2021)

Michele Simonetti, PhD student/Crosetto group (January 2016 – December 2021)

Federico Agostini, Postdoc/Bienko group (July 2018 – September 2021)

Sofia Onorato, Erasmus student/Crosetto group (April 2021 – August 2021)

Eleanor Mackey, Bachelor student/Bienko group (June 2021 – August 2021)

Dora Grassini, Visiting MD/Crosetto group (March 2021 – August 2021)

Ning Zhang, Postdoc/Crosetto group (May 2019 – May 2021)

Maud Schweitzer, Research Assistant/Crosetto group (January 2019 – April 2021)

Thu Nguyen, Bachelor student/Crosetto group (August 2020 – Jan 2021)

Silvano Garnerone, Senior scientist/Crosetto group (Feb 2015 – Dec 2020)

Tomasz Kallas, PhD student/Bienko group (Jan 2015 – Dec 2020)

Niki Vontzou, Master student/Bienko group (May 2020 – July 2020)

Marcin Nicoś, Postdoc/Crosetto group (Jan 2018 – Jun 2020)

Joaquín Custodio, Postdoc/Bienko group (May 2015 – Jun 2020)

Carla Rossell, Research Assistant/Crosetto group (June 2018 – Jun 2020)

Radosław Grochowski, Visiting Student/Crosetto group (Oct 2019 – April 2020)

Gustaw Eriksson, Master student/Crosetto group (Aug 2019 – April 2020)

Sólrún Kolbeinsdóttir, Research Assistant/Crosetto group (November 2018 – April 2020)

Merula Stout, Erasmus student/Crosetto group (Aug 2019 – Mar 2020)

Spark Yaddav, Visiting student/Bienko group (Dec 2019 – Mar 2020)

Xiaolu Zhang, Postdoc/Crosetto group (2015 – 2019)

Reza Mirzazadeh, PhD student/Crosetto group (2015 – 2019)

Cecilia Derory, Erasmus student from France/Crosetto group (May – Sep 2019)

Ricardo Daniel Estrada Moreno, Summer IFMSA student from Mexico/Crosetto group (Jul 2019 – Sep 2019)

Mukhar Jain, Bachelor’s student from India/Bienko group (Jun 2019 – Jul 2019)

Sudhish P, Bachelor’s student from India/Bienko group (Jun 2019 – Jul 2019)

Gabriel Felicio Dos Santos, M.D. student from Brazil/Crosetto group (Jul 2019)

Jesko Wagner, Bachelor’s student from Germany/Crosetto group (Feb 2019 – Jun 2019)

Xinge Li, PhD student/Bienko group (Sep 2016 – Oct 2018)

Katalin Ferenc, Research assistant/Crosetto group (Jun – Aug 2018)

Julie Roux, Erasmus student from France/Crosetto group (May – Sep 2018)

Julie Miltenburg, Erasmus student from the Netherlands/Bienko group (Feb – Jul 2018)

Dominika Stanko, Summer student from Poland/Bienko group (Jul – Aug 2017)

Chiara De Camillo, Erasmus student from Italy/Crosetto group (Jun – Aug 2017)

Katalin Ferenc, Master’s student at Karolinska Institutet/Crosetto group (Feb – Aug 2017)

Theresa Noemi Vonderheit, Erasmus student from Germany/Crosetto group (Feb – Jul 2017)

Masahiro Matsumoto, Visiting researcher from Sony Inc., Japan/Crosetto group (Oct 2016 – Nov 2017)

Diana Hernandez, Master’s student from Karolinska Institutet/Bienko group (Jan – Oct 2017)

Oliwia Koczy, Summer student from Poland/Crosetto group (Jul – Aug 2016)

Olivia Frenoy, Erasmus student from France/Bienko group (Apr – Aug 2016)

Pontus Hojer, Master’s student at KTH/Bienko group (Jun – Aug 2016)