Pathophysiological mechanisms of cardiovascular and inflammatory diseases – Research group Peder Olofsson

We study cellular and molecular mechanisms of cardiovascular and inflammatory diseases with the aim to contribute building blocks for improved therapy and better outcomes.

Part of the Department of Medicine, Solna

Our research

Overactive inflammation causes increased morbidity and mortality, not least in cardiovascular disease, the most common cause of death in the world.

By combining studies of molecular mechanisms in model systems and large-scale analysis (omics) of our own clinical cohorts, we aim to elucidate the mechanisms behind cardiovascular and inflammatory diseases. A better understanding of the physiological mechanisms that drive disease development promises better opportunities for treatment and prevention.

The figure shows that the group combines immunology, neuroscience, vascular biology and bioinformatics.
The Olofsson group combines immunology, neuroscience, vascular biology and bioinformatics and strives to define pathophysiological molecular mechanisms with clinical relevance to contribute to improved treatment and prevention of cardiovascular and inflammatory diseases. Illustration: Laura Tarnawski.

Teams

The disease mechanisms are complex and in the group there are six teams that work together with complementary perspectives to study inflammation and blood vessel biology.

Detailed cellular and molecular characterization can provide important insights into physiological mechanisms (www.proteinatlas.org).

Staff and contact

Group leader

All members of the group