Computational and Affective Psychiatry Lab (CAP Lab) – Marc Guitart Masip's Research Group

The research group uses computational models of behaviour to investigate the cognitive and computational mechanisms underlying psychiatric disorders and their relation to brain processes. By parametrising individual differences, the group identifies cognitive phenotypes in patients and examines their relation to clinical outcomes. The research aims to generate knowledge that can help improve clinical practice in psychiatry.

The research group focuses on computational psychiatry and affective decision-making processes. Using behavioural experiments, computational models, and neuroimaging, the group investigates how psychiatric symptoms emerge from disrupted brain computations. The research examines how the brain forms expectations, learns from reward, and regulates motivation, and how individual differences in these processes relate to affective disorders, particularly recurrent depression and bipolar disorder.

By combining longitudinal digital assessments with mechanistic modelling, the group develops quantitative cognitive phenotypes and investigates how these can improve diagnosis, predict illness trajectories, and guide personalised treatment.

Publications

All publications from group members