Autoimmune diseases – Research group Olle Kämpe

Our research group focuses mainly on model diseases, such as rare diseases like Addison's disease.

More about our research

Rare disease provides broader knowledge.
Olle Kämpe is professor of clinical endocrinology and is researching autoimmunity. By studying specific diseases such as Addison's disease and APS-1, he wants to increase a broader understanding of how and why the body's immune system attacks its own tissues. His research has resulted in new diagnostic methods, and may eventually lead to new treatments.
(Karolinska Institutet, 2014.)

The search for a vaccine (video).
Is it possible to stop “Addison's disease” and other autoimmune diseases? That is the hope of Olle Kämpe, who is a clinical researcher at Karolinska Institutet. It is not known what initiates an auto immune reaction, just that it starts several years before the patients come to clinical care. Kämpe and his group has discovered that the immune system in all patients with Addison's disease reacted to the very same substance – the enzyme 21-hydroxylase. Kämpe and this team are working on a promising treatment for patients with Addison's. You’ll meet Olle Kämpe and his patient Eva Raffner.
(The Wallenberg Foundations, 2024.)

Publications

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Staff and contact

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Keywords:
Autoimmunity and Inflammation Endocrinology and Diabetes Medical Genetics and Genomics Rheumatology
Content reviewer:
20-03-2025